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Center for Computational Systems Medicine
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FusionGeneSummary

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FusionProtFeature

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FusionGeneSequence

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FusionGenePPI

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RelatedDrugs

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RelatedDiseases

Fusion gene ID: 19098

FusionGeneSummary for KMT2A_KMT2A

check button Fusion gene summary
Fusion gene informationFusion gene name: KMT2A_KMT2A
Fusion gene ID: 19098
HgeneTgene
Gene symbol

KMT2A

KMT2A

Gene ID

4297

4297

Gene namelysine methyltransferase 2Alysine methyltransferase 2A
SynonymsALL-1|CXXC7|HRX|HTRX1|MLL|MLL1|MLL1A|TRX1|WDSTSALL-1|CXXC7|HRX|HTRX1|MLL|MLL1|MLL1A|TRX1|WDSTS
Cytomap

11q23.3

11q23.3

Type of geneprotein-codingprotein-coding
Descriptionhistone-lysine N-methyltransferase 2ACXXC-type zinc finger protein 7lysine (K)-specific methyltransferase 2Alysine N-methyltransferase 2Amixed lineage leukemia 1myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)trithorax-likehistone-lysine N-methyltransferase 2ACXXC-type zinc finger protein 7lysine (K)-specific methyltransferase 2Alysine N-methyltransferase 2Amixed lineage leukemia 1myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)trithorax-like
Modification date2018051920180519
UniProtAcc

Q03164

Q03164

Ensembl transtripts involved in fusion geneENST00000534358, ENST00000389506, 
ENST00000354520, ENST00000420751, 
ENST00000534358, ENST00000389506, 
ENST00000354520, ENST00000420751, 
Fusion gene scores* DoF score31 X 72 X 6=1339215 X 40 X 1=600
# samples 12958
** MAII scorelog2(129/13392*10)=-3.37592846223973
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(58/600*10)=-0.0489096004809464
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: KMT2A [Title/Abstract] AND KMT2A [Title/Abstract] AND fusion [Title/Abstract]

Functional or gene categories assigned by FusionGDB annotationOncogene involved fusion gene, in-frame and retained their domain.
Transcription factor involved fusion gene, inframe and retained DNA-binding domain.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneKMT2A

GO:0045944

positive regulation of transcription by RNA polymerase II

20861184

HgeneKMT2A

GO:0051568

histone H3-K4 methylation

19556245

HgeneKMT2A

GO:0065003

protein-containing complex assembly

15199122

HgeneKMT2A

GO:0080182

histone H3-K4 trimethylation

20861184

TgeneKMT2A

GO:0045944

positive regulation of transcription by RNA polymerase II

20861184

TgeneKMT2A

GO:0051568

histone H3-K4 methylation

19556245

TgeneKMT2A

GO:0065003

protein-containing complex assembly

15199122

TgeneKMT2A

GO:0080182

histone H3-K4 trimethylation

20861184


check button Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
Data typeSourceCancer typeSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChiTaRS3.1AY187942KMT2Achr11

118353215

+KMT2Achr11

118339488

+
ChiTaRS3.1AF272371KMT2Achr11

118359411

+KMT2Achr11

118352667

-
ChiTaRS3.1AY187945KMT2Achr11

118355030

+KMT2Achr11

118339488

+
ChiTaRS3.1AF232001KMT2Achr11

118363838

+KMT2Achr11

118352667

-
ChiTaRS3.1AF272382KMT2Achr11

118350944

+KMT2Achr11

118352667

-
ChiTaRS3.1AF272381KMT2Achr11

118360593

+KMT2Achr11

118352667

-
ChiTaRS3.1AF272380KMT2Achr11

118359411

+KMT2Achr11

118352668

-
ChiTaRS3.1AY187943KMT2Achr11

118353215

+KMT2Achr11

118339488

+
ChiTaRS3.1AY187944KMT2Achr11

118355030

+KMT2Achr11

118339488

+
ChiTaRS3.1AF232000KMT2Achr11

118359411

+KMT2Achr11

118352664

-
ChiTaRS3.1AF024540KMT2Achr11

118353215

+KMT2Achr11

118339488

+
ChiTaRS3.1BQ423051KMT2Achr11

118394603

-KMT2Achr11

118395263

+
ChiTaRS3.1AF272372KMT2Achr11

118353210

+KMT2Achr11

118352428

+
ChiTaRS3.1DB147747KMT2Achr11

118391992

+KMT2Achr11

118372433

+
ChiTaRS3.1AF272379KMT2Achr11

118355590

+KMT2Achr11

118352667

-
* LD: Li Ding group's fusion gene list
  RV: Roel Verhaak group's fusion gene list
  ChiTaRs fusion database

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000534358ENST00000534358KMT2Achr11

118353215

+KMT2Achr11

118339488

+
In-frameENST00000534358ENST00000389506KMT2Achr11

118353215

+KMT2Achr11

118339488

+
In-frameENST00000534358ENST00000354520KMT2Achr11

118353215

+KMT2Achr11

118339488

+
5CDS-intronENST00000534358ENST00000420751KMT2Achr11

118353215

+KMT2Achr11

118339488

+
In-frameENST00000389506ENST00000534358KMT2Achr11

118353215

+KMT2Achr11

118339488

+
In-frameENST00000389506ENST00000389506KMT2Achr11

118353215

+KMT2Achr11

118339488

+
In-frameENST00000389506ENST00000354520KMT2Achr11

118353215

+KMT2Achr11

118339488

+
5CDS-intronENST00000389506ENST00000420751KMT2Achr11

118353215

+KMT2Achr11

118339488

+
In-frameENST00000354520ENST00000534358KMT2Achr11

118353215

+KMT2Achr11

118339488

+
In-frameENST00000354520ENST00000389506KMT2Achr11

118353215

+KMT2Achr11

118339488

+
In-frameENST00000354520ENST00000354520KMT2Achr11

118353215

+KMT2Achr11

118339488

+
5CDS-intronENST00000354520ENST00000420751KMT2Achr11

118353215

+KMT2Achr11

118339488

+
intron-3CDSENST00000420751ENST00000534358KMT2Achr11

118353215

+KMT2Achr11

118339488

+
intron-3CDSENST00000420751ENST00000389506KMT2Achr11

118353215

+KMT2Achr11

118339488

+
intron-3CDSENST00000420751ENST00000354520KMT2Achr11

118353215

+KMT2Achr11

118339488

+
intron-intronENST00000420751ENST00000420751KMT2Achr11

118353215

+KMT2Achr11

118339488

+
Frame-shiftENST00000534358ENST00000534358KMT2Achr11

118359411

+KMT2Achr11

118352667

-
Frame-shiftENST00000534358ENST00000389506KMT2Achr11

118359411

+KMT2Achr11

118352667

-
Frame-shiftENST00000534358ENST00000354520KMT2Achr11

118359411

+KMT2Achr11

118352667

-
5CDS-intronENST00000534358ENST00000420751KMT2Achr11

118359411

+KMT2Achr11

118352667

-
Frame-shiftENST00000389506ENST00000534358KMT2Achr11

118359411

+KMT2Achr11

118352667

-
Frame-shiftENST00000389506ENST00000389506KMT2Achr11

118359411

+KMT2Achr11

118352667

-
Frame-shiftENST00000389506ENST00000354520KMT2Achr11

118359411

+KMT2Achr11

118352667

-
5CDS-intronENST00000389506ENST00000420751KMT2Achr11

118359411

+KMT2Achr11

118352667

-
Frame-shiftENST00000354520ENST00000534358KMT2Achr11

118359411

+KMT2Achr11

118352667

-
Frame-shiftENST00000354520ENST00000389506KMT2Achr11

118359411

+KMT2Achr11

118352667

-
Frame-shiftENST00000354520ENST00000354520KMT2Achr11

118359411

+KMT2Achr11

118352667

-
5CDS-intronENST00000354520ENST00000420751KMT2Achr11

118359411

+KMT2Achr11

118352667

-
intron-3CDSENST00000420751ENST00000534358KMT2Achr11

118359411

+KMT2Achr11

118352667

-
intron-3CDSENST00000420751ENST00000389506KMT2Achr11

118359411

+KMT2Achr11

118352667

-
intron-3CDSENST00000420751ENST00000354520KMT2Achr11

118359411

+KMT2Achr11

118352667

-
intron-intronENST00000420751ENST00000420751KMT2Achr11

118359411

+KMT2Achr11

118352667

-
In-frameENST00000534358ENST00000534358KMT2Achr11

118355030

+KMT2Achr11

118339488

+
In-frameENST00000534358ENST00000389506KMT2Achr11

118355030

+KMT2Achr11

118339488

+
In-frameENST00000534358ENST00000354520KMT2Achr11

118355030

+KMT2Achr11

118339488

+
5CDS-intronENST00000534358ENST00000420751KMT2Achr11

118355030

+KMT2Achr11

118339488

+
In-frameENST00000389506ENST00000534358KMT2Achr11

118355030

+KMT2Achr11

118339488

+
In-frameENST00000389506ENST00000389506KMT2Achr11

118355030

+KMT2Achr11

118339488

+
In-frameENST00000389506ENST00000354520KMT2Achr11

118355030

+KMT2Achr11

118339488

+
5CDS-intronENST00000389506ENST00000420751KMT2Achr11

118355030

+KMT2Achr11

118339488

+
In-frameENST00000354520ENST00000534358KMT2Achr11

118355030

+KMT2Achr11

118339488

+
In-frameENST00000354520ENST00000389506KMT2Achr11

118355030

+KMT2Achr11

118339488

+
In-frameENST00000354520ENST00000354520KMT2Achr11

118355030

+KMT2Achr11

118339488

+
5CDS-intronENST00000354520ENST00000420751KMT2Achr11

118355030

+KMT2Achr11

118339488

+
3UTR-3CDSENST00000420751ENST00000534358KMT2Achr11

118355030

+KMT2Achr11

118339488

+
3UTR-3CDSENST00000420751ENST00000389506KMT2Achr11

118355030

+KMT2Achr11

118339488

+
3UTR-3CDSENST00000420751ENST00000354520KMT2Achr11

118355030

+KMT2Achr11

118339488

+
3UTR-intronENST00000420751ENST00000420751KMT2Achr11

118355030

+KMT2Achr11

118339488

+
Frame-shiftENST00000534358ENST00000534358KMT2Achr11

118363838

+KMT2Achr11

118352667

-
Frame-shiftENST00000534358ENST00000389506KMT2Achr11

118363838

+KMT2Achr11

118352667

-
Frame-shiftENST00000534358ENST00000354520KMT2Achr11

118363838

+KMT2Achr11

118352667

-
5CDS-intronENST00000534358ENST00000420751KMT2Achr11

118363838

+KMT2Achr11

118352667

-
Frame-shiftENST00000389506ENST00000534358KMT2Achr11

118363838

+KMT2Achr11

118352667

-
Frame-shiftENST00000389506ENST00000389506KMT2Achr11

118363838

+KMT2Achr11

118352667

-
Frame-shiftENST00000389506ENST00000354520KMT2Achr11

118363838

+KMT2Achr11

118352667

-
5CDS-intronENST00000389506ENST00000420751KMT2Achr11

118363838

+KMT2Achr11

118352667

-
Frame-shiftENST00000354520ENST00000534358KMT2Achr11

118363838

+KMT2Achr11

118352667

-
Frame-shiftENST00000354520ENST00000389506KMT2Achr11

118363838

+KMT2Achr11

118352667

-
Frame-shiftENST00000354520ENST00000354520KMT2Achr11

118363838

+KMT2Achr11

118352667

-
5CDS-intronENST00000354520ENST00000420751KMT2Achr11

118363838

+KMT2Achr11

118352667

-
intron-3CDSENST00000420751ENST00000534358KMT2Achr11

118363838

+KMT2Achr11

118352667

-
intron-3CDSENST00000420751ENST00000389506KMT2Achr11

118363838

+KMT2Achr11

118352667

-
intron-3CDSENST00000420751ENST00000354520KMT2Achr11

118363838

+KMT2Achr11

118352667

-
intron-intronENST00000420751ENST00000420751KMT2Achr11

118363838

+KMT2Achr11

118352667

-
In-frameENST00000534358ENST00000534358KMT2Achr11

118350944

+KMT2Achr11

118352667

-
In-frameENST00000534358ENST00000389506KMT2Achr11

118350944

+KMT2Achr11

118352667

-
In-frameENST00000534358ENST00000354520KMT2Achr11

118350944

+KMT2Achr11

118352667

-
5CDS-intronENST00000534358ENST00000420751KMT2Achr11

118350944

+KMT2Achr11

118352667

-
In-frameENST00000389506ENST00000534358KMT2Achr11

118350944

+KMT2Achr11

118352667

-
In-frameENST00000389506ENST00000389506KMT2Achr11

118350944

+KMT2Achr11

118352667

-
In-frameENST00000389506ENST00000354520KMT2Achr11

118350944

+KMT2Achr11

118352667

-
5CDS-intronENST00000389506ENST00000420751KMT2Achr11

118350944

+KMT2Achr11

118352667

-
In-frameENST00000354520ENST00000534358KMT2Achr11

118350944

+KMT2Achr11

118352667

-
In-frameENST00000354520ENST00000389506KMT2Achr11

118350944

+KMT2Achr11

118352667

-
In-frameENST00000354520ENST00000354520KMT2Achr11

118350944

+KMT2Achr11

118352667

-
5CDS-intronENST00000354520ENST00000420751KMT2Achr11

118350944

+KMT2Achr11

118352667

-
intron-3CDSENST00000420751ENST00000534358KMT2Achr11

118350944

+KMT2Achr11

118352667

-
intron-3CDSENST00000420751ENST00000389506KMT2Achr11

118350944

+KMT2Achr11

118352667

-
intron-3CDSENST00000420751ENST00000354520KMT2Achr11

118350944

+KMT2Achr11

118352667

-
intron-intronENST00000420751ENST00000420751KMT2Achr11

118350944

+KMT2Achr11

118352667

-
Frame-shiftENST00000534358ENST00000534358KMT2Achr11

118360593

+KMT2Achr11

118352667

-
Frame-shiftENST00000534358ENST00000389506KMT2Achr11

118360593

+KMT2Achr11

118352667

-
Frame-shiftENST00000534358ENST00000354520KMT2Achr11

118360593

+KMT2Achr11

118352667

-
5CDS-intronENST00000534358ENST00000420751KMT2Achr11

118360593

+KMT2Achr11

118352667

-
Frame-shiftENST00000389506ENST00000534358KMT2Achr11

118360593

+KMT2Achr11

118352667

-
Frame-shiftENST00000389506ENST00000389506KMT2Achr11

118360593

+KMT2Achr11

118352667

-
Frame-shiftENST00000389506ENST00000354520KMT2Achr11

118360593

+KMT2Achr11

118352667

-
5CDS-intronENST00000389506ENST00000420751KMT2Achr11

118360593

+KMT2Achr11

118352667

-
Frame-shiftENST00000354520ENST00000534358KMT2Achr11

118360593

+KMT2Achr11

118352667

-
Frame-shiftENST00000354520ENST00000389506KMT2Achr11

118360593

+KMT2Achr11

118352667

-
Frame-shiftENST00000354520ENST00000354520KMT2Achr11

118360593

+KMT2Achr11

118352667

-
5CDS-intronENST00000354520ENST00000420751KMT2Achr11

118360593

+KMT2Achr11

118352667

-
intron-3CDSENST00000420751ENST00000534358KMT2Achr11

118360593

+KMT2Achr11

118352667

-
intron-3CDSENST00000420751ENST00000389506KMT2Achr11

118360593

+KMT2Achr11

118352667

-
intron-3CDSENST00000420751ENST00000354520KMT2Achr11

118360593

+KMT2Achr11

118352667

-
intron-intronENST00000420751ENST00000420751KMT2Achr11

118360593

+KMT2Achr11

118352667

-
Frame-shiftENST00000534358ENST00000534358KMT2Achr11

118359411

+KMT2Achr11

118352668

-
Frame-shiftENST00000534358ENST00000389506KMT2Achr11

118359411

+KMT2Achr11

118352668

-
Frame-shiftENST00000534358ENST00000354520KMT2Achr11

118359411

+KMT2Achr11

118352668

-
5CDS-intronENST00000534358ENST00000420751KMT2Achr11

118359411

+KMT2Achr11

118352668

-
Frame-shiftENST00000389506ENST00000534358KMT2Achr11

118359411

+KMT2Achr11

118352668

-
Frame-shiftENST00000389506ENST00000389506KMT2Achr11

118359411

+KMT2Achr11

118352668

-
Frame-shiftENST00000389506ENST00000354520KMT2Achr11

118359411

+KMT2Achr11

118352668

-
5CDS-intronENST00000389506ENST00000420751KMT2Achr11

118359411

+KMT2Achr11

118352668

-
Frame-shiftENST00000354520ENST00000534358KMT2Achr11

118359411

+KMT2Achr11

118352668

-
Frame-shiftENST00000354520ENST00000389506KMT2Achr11

118359411

+KMT2Achr11

118352668

-
Frame-shiftENST00000354520ENST00000354520KMT2Achr11

118359411

+KMT2Achr11

118352668

-
5CDS-intronENST00000354520ENST00000420751KMT2Achr11

118359411

+KMT2Achr11

118352668

-
intron-3CDSENST00000420751ENST00000534358KMT2Achr11

118359411

+KMT2Achr11

118352668

-
intron-3CDSENST00000420751ENST00000389506KMT2Achr11

118359411

+KMT2Achr11

118352668

-
intron-3CDSENST00000420751ENST00000354520KMT2Achr11

118359411

+KMT2Achr11

118352668

-
intron-intronENST00000420751ENST00000420751KMT2Achr11

118359411

+KMT2Achr11

118352668

-
Frame-shiftENST00000534358ENST00000534358KMT2Achr11

118359411

+KMT2Achr11

118352664

-
Frame-shiftENST00000534358ENST00000389506KMT2Achr11

118359411

+KMT2Achr11

118352664

-
Frame-shiftENST00000534358ENST00000354520KMT2Achr11

118359411

+KMT2Achr11

118352664

-
5CDS-intronENST00000534358ENST00000420751KMT2Achr11

118359411

+KMT2Achr11

118352664

-
Frame-shiftENST00000389506ENST00000534358KMT2Achr11

118359411

+KMT2Achr11

118352664

-
Frame-shiftENST00000389506ENST00000389506KMT2Achr11

118359411

+KMT2Achr11

118352664

-
Frame-shiftENST00000389506ENST00000354520KMT2Achr11

118359411

+KMT2Achr11

118352664

-
5CDS-intronENST00000389506ENST00000420751KMT2Achr11

118359411

+KMT2Achr11

118352664

-
Frame-shiftENST00000354520ENST00000534358KMT2Achr11

118359411

+KMT2Achr11

118352664

-
Frame-shiftENST00000354520ENST00000389506KMT2Achr11

118359411

+KMT2Achr11

118352664

-
Frame-shiftENST00000354520ENST00000354520KMT2Achr11

118359411

+KMT2Achr11

118352664

-
5CDS-intronENST00000354520ENST00000420751KMT2Achr11

118359411

+KMT2Achr11

118352664

-
intron-3CDSENST00000420751ENST00000534358KMT2Achr11

118359411

+KMT2Achr11

118352664

-
intron-3CDSENST00000420751ENST00000389506KMT2Achr11

118359411

+KMT2Achr11

118352664

-
intron-3CDSENST00000420751ENST00000354520KMT2Achr11

118359411

+KMT2Achr11

118352664

-
intron-intronENST00000420751ENST00000420751KMT2Achr11

118359411

+KMT2Achr11

118352664

-
3UTR-3UTRENST00000534358ENST00000534358KMT2Achr11

118394603

-KMT2Achr11

118395263

+
3UTR-intronENST00000534358ENST00000389506KMT2Achr11

118394603

-KMT2Achr11

118395263

+
3UTR-3UTRENST00000534358ENST00000354520KMT2Achr11

118394603

-KMT2Achr11

118395263

+
3UTR-intronENST00000534358ENST00000420751KMT2Achr11

118394603

-KMT2Achr11

118395263

+
3UTR-3UTRENST00000389506ENST00000534358KMT2Achr11

118394603

-KMT2Achr11

118395263

+
3UTR-intronENST00000389506ENST00000389506KMT2Achr11

118394603

-KMT2Achr11

118395263

+
3UTR-3UTRENST00000389506ENST00000354520KMT2Achr11

118394603

-KMT2Achr11

118395263

+
3UTR-intronENST00000389506ENST00000420751KMT2Achr11

118394603

-KMT2Achr11

118395263

+
3UTR-3UTRENST00000354520ENST00000534358KMT2Achr11

118394603

-KMT2Achr11

118395263

+
3UTR-intronENST00000354520ENST00000389506KMT2Achr11

118394603

-KMT2Achr11

118395263

+
3UTR-3UTRENST00000354520ENST00000354520KMT2Achr11

118394603

-KMT2Achr11

118395263

+
3UTR-intronENST00000354520ENST00000420751KMT2Achr11

118394603

-KMT2Achr11

118395263

+
intron-3UTRENST00000420751ENST00000534358KMT2Achr11

118394603

-KMT2Achr11

118395263

+
intron-intronENST00000420751ENST00000389506KMT2Achr11

118394603

-KMT2Achr11

118395263

+
intron-3UTRENST00000420751ENST00000354520KMT2Achr11

118394603

-KMT2Achr11

118395263

+
intron-intronENST00000420751ENST00000420751KMT2Achr11

118394603

-KMT2Achr11

118395263

+
Frame-shiftENST00000534358ENST00000534358KMT2Achr11

118353210

+KMT2Achr11

118352428

+
Frame-shiftENST00000534358ENST00000389506KMT2Achr11

118353210

+KMT2Achr11

118352428

+
Frame-shiftENST00000534358ENST00000354520KMT2Achr11

118353210

+KMT2Achr11

118352428

+
5CDS-intronENST00000534358ENST00000420751KMT2Achr11

118353210

+KMT2Achr11

118352428

+
Frame-shiftENST00000389506ENST00000534358KMT2Achr11

118353210

+KMT2Achr11

118352428

+
Frame-shiftENST00000389506ENST00000389506KMT2Achr11

118353210

+KMT2Achr11

118352428

+
Frame-shiftENST00000389506ENST00000354520KMT2Achr11

118353210

+KMT2Achr11

118352428

+
5CDS-intronENST00000389506ENST00000420751KMT2Achr11

118353210

+KMT2Achr11

118352428

+
Frame-shiftENST00000354520ENST00000534358KMT2Achr11

118353210

+KMT2Achr11

118352428

+
Frame-shiftENST00000354520ENST00000389506KMT2Achr11

118353210

+KMT2Achr11

118352428

+
Frame-shiftENST00000354520ENST00000354520KMT2Achr11

118353210

+KMT2Achr11

118352428

+
5CDS-intronENST00000354520ENST00000420751KMT2Achr11

118353210

+KMT2Achr11

118352428

+
intron-3CDSENST00000420751ENST00000534358KMT2Achr11

118353210

+KMT2Achr11

118352428

+
intron-3CDSENST00000420751ENST00000389506KMT2Achr11

118353210

+KMT2Achr11

118352428

+
intron-3CDSENST00000420751ENST00000354520KMT2Achr11

118353210

+KMT2Achr11

118352428

+
intron-intronENST00000420751ENST00000420751KMT2Achr11

118353210

+KMT2Achr11

118352428

+
intron-3CDSENST00000534358ENST00000534358KMT2Achr11

118391992

+KMT2Achr11

118372433

+
intron-3CDSENST00000534358ENST00000389506KMT2Achr11

118391992

+KMT2Achr11

118372433

+
intron-3CDSENST00000534358ENST00000354520KMT2Achr11

118391992

+KMT2Achr11

118372433

+
intron-intronENST00000534358ENST00000420751KMT2Achr11

118391992

+KMT2Achr11

118372433

+
intron-3CDSENST00000389506ENST00000534358KMT2Achr11

118391992

+KMT2Achr11

118372433

+
intron-3CDSENST00000389506ENST00000389506KMT2Achr11

118391992

+KMT2Achr11

118372433

+
intron-3CDSENST00000389506ENST00000354520KMT2Achr11

118391992

+KMT2Achr11

118372433

+
intron-intronENST00000389506ENST00000420751KMT2Achr11

118391992

+KMT2Achr11

118372433

+
intron-3CDSENST00000354520ENST00000534358KMT2Achr11

118391992

+KMT2Achr11

118372433

+
intron-3CDSENST00000354520ENST00000389506KMT2Achr11

118391992

+KMT2Achr11

118372433

+
intron-3CDSENST00000354520ENST00000354520KMT2Achr11

118391992

+KMT2Achr11

118372433

+
intron-intronENST00000354520ENST00000420751KMT2Achr11

118391992

+KMT2Achr11

118372433

+
intron-3CDSENST00000420751ENST00000534358KMT2Achr11

118391992

+KMT2Achr11

118372433

+
intron-3CDSENST00000420751ENST00000389506KMT2Achr11

118391992

+KMT2Achr11

118372433

+
intron-3CDSENST00000420751ENST00000354520KMT2Achr11

118391992

+KMT2Achr11

118372433

+
intron-intronENST00000420751ENST00000420751KMT2Achr11

118391992

+KMT2Achr11

118372433

+
Frame-shiftENST00000534358ENST00000534358KMT2Achr11

118355590

+KMT2Achr11

118352667

-
Frame-shiftENST00000534358ENST00000389506KMT2Achr11

118355590

+KMT2Achr11

118352667

-
Frame-shiftENST00000534358ENST00000354520KMT2Achr11

118355590

+KMT2Achr11

118352667

-
5CDS-intronENST00000534358ENST00000420751KMT2Achr11

118355590

+KMT2Achr11

118352667

-
Frame-shiftENST00000389506ENST00000534358KMT2Achr11

118355590

+KMT2Achr11

118352667

-
Frame-shiftENST00000389506ENST00000389506KMT2Achr11

118355590

+KMT2Achr11

118352667

-
Frame-shiftENST00000389506ENST00000354520KMT2Achr11

118355590

+KMT2Achr11

118352667

-
5CDS-intronENST00000389506ENST00000420751KMT2Achr11

118355590

+KMT2Achr11

118352667

-
intron-3CDSENST00000354520ENST00000534358KMT2Achr11

118355590

+KMT2Achr11

118352667

-
intron-3CDSENST00000354520ENST00000389506KMT2Achr11

118355590

+KMT2Achr11

118352667

-
intron-3CDSENST00000354520ENST00000354520KMT2Achr11

118355590

+KMT2Achr11

118352667

-
intron-intronENST00000354520ENST00000420751KMT2Achr11

118355590

+KMT2Achr11

118352667

-
intron-3CDSENST00000420751ENST00000534358KMT2Achr11

118355590

+KMT2Achr11

118352667

-
intron-3CDSENST00000420751ENST00000389506KMT2Achr11

118355590

+KMT2Achr11

118352667

-
intron-3CDSENST00000420751ENST00000354520KMT2Achr11

118355590

+KMT2Achr11

118352667

-
intron-intronENST00000420751ENST00000420751KMT2Achr11

118355590

+KMT2Achr11

118352667

-

Top

FusionProtFeatures for KMT2A_KMT2A


check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
KMT2A

Q03164

KMT2A

Q03164


check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

.

* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneKMT2Achr11:118353215chr11:118339488ENST00000354520+835137_14313623932Compositional biasNote=Poly-Gly
HgeneKMT2Achr11:118353215chr11:118339488ENST00000354520+83517_10213623932Compositional biasNote=Ala/Gly/Ser-rich
HgeneKMT2Achr11:118353215chr11:118339488ENST00000354520+835561_56413623932Compositional biasNote=Poly-Pro
HgeneKMT2Achr11:118353215chr11:118339488ENST00000354520+835568_57113623932Compositional biasNote=Poly-Pro
HgeneKMT2Achr11:118353215chr11:118339488ENST00000389506+836137_14313623970Compositional biasNote=Poly-Gly
HgeneKMT2Achr11:118353215chr11:118339488ENST00000389506+83617_10213623970Compositional biasNote=Ala/Gly/Ser-rich
HgeneKMT2Achr11:118353215chr11:118339488ENST00000389506+836561_56413623970Compositional biasNote=Poly-Pro
HgeneKMT2Achr11:118353215chr11:118339488ENST00000389506+836568_57113623970Compositional biasNote=Poly-Pro
HgeneKMT2Achr11:118353215chr11:118339488ENST00000534358+836137_14313623973Compositional biasNote=Poly-Gly
HgeneKMT2Achr11:118353215chr11:118339488ENST00000534358+83617_10213623973Compositional biasNote=Ala/Gly/Ser-rich
HgeneKMT2Achr11:118353215chr11:118339488ENST00000534358+836561_56413623973Compositional biasNote=Poly-Pro
HgeneKMT2Achr11:118353215chr11:118339488ENST00000534358+836568_57113623973Compositional biasNote=Poly-Pro
HgeneKMT2Achr11:118355030chr11:118339488ENST00000354520+935137_14314063932Compositional biasNote=Poly-Gly
HgeneKMT2Achr11:118355030chr11:118339488ENST00000354520+93517_10214063932Compositional biasNote=Ala/Gly/Ser-rich
HgeneKMT2Achr11:118355030chr11:118339488ENST00000354520+935561_56414063932Compositional biasNote=Poly-Pro
HgeneKMT2Achr11:118355030chr11:118339488ENST00000354520+935568_57114063932Compositional biasNote=Poly-Pro
HgeneKMT2Achr11:118355030chr11:118339488ENST00000389506+936137_14314063970Compositional biasNote=Poly-Gly
HgeneKMT2Achr11:118355030chr11:118339488ENST00000389506+93617_10214063970Compositional biasNote=Ala/Gly/Ser-rich
HgeneKMT2Achr11:118355030chr11:118339488ENST00000389506+936561_56414063970Compositional biasNote=Poly-Pro
HgeneKMT2Achr11:118355030chr11:118339488ENST00000389506+936568_57114063970Compositional biasNote=Poly-Pro
HgeneKMT2Achr11:118355030chr11:118339488ENST00000534358+936137_14314063973Compositional biasNote=Poly-Gly
HgeneKMT2Achr11:118355030chr11:118339488ENST00000534358+93617_10214063973Compositional biasNote=Ala/Gly/Ser-rich
HgeneKMT2Achr11:118355030chr11:118339488ENST00000534358+936561_56414063973Compositional biasNote=Poly-Pro
HgeneKMT2Achr11:118355030chr11:118339488ENST00000534358+936568_57114063973Compositional biasNote=Poly-Pro
HgeneKMT2Achr11:118353215chr11:118339488ENST00000354520+835169_18013623932DNA bindingNote=A.T hook 1
HgeneKMT2Achr11:118353215chr11:118339488ENST00000354520+835217_22713623932DNA bindingNote=A.T hook 2
HgeneKMT2Achr11:118353215chr11:118339488ENST00000354520+835301_30913623932DNA bindingNote=A.T hook 3
HgeneKMT2Achr11:118353215chr11:118339488ENST00000389506+836169_18013623970DNA bindingNote=A.T hook 1
HgeneKMT2Achr11:118353215chr11:118339488ENST00000389506+836217_22713623970DNA bindingNote=A.T hook 2
HgeneKMT2Achr11:118353215chr11:118339488ENST00000389506+836301_30913623970DNA bindingNote=A.T hook 3
HgeneKMT2Achr11:118353215chr11:118339488ENST00000534358+836169_18013623973DNA bindingNote=A.T hook 1
HgeneKMT2Achr11:118353215chr11:118339488ENST00000534358+836217_22713623973DNA bindingNote=A.T hook 2
HgeneKMT2Achr11:118353215chr11:118339488ENST00000534358+836301_30913623973DNA bindingNote=A.T hook 3
HgeneKMT2Achr11:118355030chr11:118339488ENST00000354520+935169_18014063932DNA bindingNote=A.T hook 1
HgeneKMT2Achr11:118355030chr11:118339488ENST00000354520+935217_22714063932DNA bindingNote=A.T hook 2
HgeneKMT2Achr11:118355030chr11:118339488ENST00000354520+935301_30914063932DNA bindingNote=A.T hook 3
HgeneKMT2Achr11:118355030chr11:118339488ENST00000389506+936169_18014063970DNA bindingNote=A.T hook 1
HgeneKMT2Achr11:118355030chr11:118339488ENST00000389506+936217_22714063970DNA bindingNote=A.T hook 2
HgeneKMT2Achr11:118355030chr11:118339488ENST00000389506+936301_30914063970DNA bindingNote=A.T hook 3
HgeneKMT2Achr11:118355030chr11:118339488ENST00000534358+936169_18014063973DNA bindingNote=A.T hook 1
HgeneKMT2Achr11:118355030chr11:118339488ENST00000534358+936217_22714063973DNA bindingNote=A.T hook 2
HgeneKMT2Achr11:118355030chr11:118339488ENST00000534358+936301_30914063973DNA bindingNote=A.T hook 3
HgeneKMT2Achr11:118353215chr11:118339488ENST00000354520+8351147_119513623932Zinc fingerCXXC-type
HgeneKMT2Achr11:118353215chr11:118339488ENST00000389506+8361147_119513623970Zinc fingerCXXC-type
HgeneKMT2Achr11:118353215chr11:118339488ENST00000534358+8361147_119513623973Zinc fingerCXXC-type
HgeneKMT2Achr11:118355030chr11:118339488ENST00000354520+9351147_119514063932Zinc fingerCXXC-type
HgeneKMT2Achr11:118355030chr11:118339488ENST00000389506+9361147_119514063970Zinc fingerCXXC-type
HgeneKMT2Achr11:118355030chr11:118339488ENST00000534358+9361147_119514063973Zinc fingerCXXC-type
TgeneKMT2Achr11:118350944chr11:118352667ENST00000354520+035137_14303932Compositional biasNote=Poly-Gly
TgeneKMT2Achr11:118350944chr11:118352667ENST00000354520+03517_10203932Compositional biasNote=Ala/Gly/Ser-rich
TgeneKMT2Achr11:118350944chr11:118352667ENST00000354520+035561_56403932Compositional biasNote=Poly-Pro
TgeneKMT2Achr11:118350944chr11:118352667ENST00000354520+035568_57103932Compositional biasNote=Poly-Pro
TgeneKMT2Achr11:118350944chr11:118352667ENST00000389506+036137_14303970Compositional biasNote=Poly-Gly
TgeneKMT2Achr11:118350944chr11:118352667ENST00000389506+03617_10203970Compositional biasNote=Ala/Gly/Ser-rich
TgeneKMT2Achr11:118350944chr11:118352667ENST00000389506+036561_56403970Compositional biasNote=Poly-Pro
TgeneKMT2Achr11:118350944chr11:118352667ENST00000389506+036568_57103970Compositional biasNote=Poly-Pro
TgeneKMT2Achr11:118350944chr11:118352667ENST00000534358+036137_143-83973Compositional biasNote=Poly-Gly
TgeneKMT2Achr11:118350944chr11:118352667ENST00000534358+03617_102-83973Compositional biasNote=Ala/Gly/Ser-rich
TgeneKMT2Achr11:118350944chr11:118352667ENST00000534358+036561_564-83973Compositional biasNote=Poly-Pro
TgeneKMT2Achr11:118350944chr11:118352667ENST00000534358+036568_571-83973Compositional biasNote=Poly-Pro
TgeneKMT2Achr11:118353215chr11:118339488ENST00000354520+035561_5641443932Compositional biasNote=Poly-Pro
TgeneKMT2Achr11:118353215chr11:118339488ENST00000354520+035568_5711443932Compositional biasNote=Poly-Pro
TgeneKMT2Achr11:118353215chr11:118339488ENST00000389506+036561_5641443970Compositional biasNote=Poly-Pro
TgeneKMT2Achr11:118353215chr11:118339488ENST00000389506+036568_5711443970Compositional biasNote=Poly-Pro
TgeneKMT2Achr11:118353215chr11:118339488ENST00000534358+036561_5641443973Compositional biasNote=Poly-Pro
TgeneKMT2Achr11:118353215chr11:118339488ENST00000534358+036568_5711443973Compositional biasNote=Poly-Pro
TgeneKMT2Achr11:118355030chr11:118339488ENST00000354520+035561_5641443932Compositional biasNote=Poly-Pro
TgeneKMT2Achr11:118355030chr11:118339488ENST00000354520+035568_5711443932Compositional biasNote=Poly-Pro
TgeneKMT2Achr11:118355030chr11:118339488ENST00000389506+036561_5641443970Compositional biasNote=Poly-Pro
TgeneKMT2Achr11:118355030chr11:118339488ENST00000389506+036568_5711443970Compositional biasNote=Poly-Pro
TgeneKMT2Achr11:118355030chr11:118339488ENST00000534358+036561_5641443973Compositional biasNote=Poly-Pro
TgeneKMT2Achr11:118355030chr11:118339488ENST00000534358+036568_5711443973Compositional biasNote=Poly-Pro
TgeneKMT2Achr11:118350944chr11:118352667ENST00000354520+035169_18003932DNA bindingNote=A.T hook 1
TgeneKMT2Achr11:118350944chr11:118352667ENST00000354520+035217_22703932DNA bindingNote=A.T hook 2
TgeneKMT2Achr11:118350944chr11:118352667ENST00000354520+035301_30903932DNA bindingNote=A.T hook 3
TgeneKMT2Achr11:118350944chr11:118352667ENST00000389506+036169_18003970DNA bindingNote=A.T hook 1
TgeneKMT2Achr11:118350944chr11:118352667ENST00000389506+036217_22703970DNA bindingNote=A.T hook 2
TgeneKMT2Achr11:118350944chr11:118352667ENST00000389506+036301_30903970DNA bindingNote=A.T hook 3
TgeneKMT2Achr11:118350944chr11:118352667ENST00000534358+036169_180-83973DNA bindingNote=A.T hook 1
TgeneKMT2Achr11:118350944chr11:118352667ENST00000534358+036217_227-83973DNA bindingNote=A.T hook 2
TgeneKMT2Achr11:118350944chr11:118352667ENST00000534358+036301_309-83973DNA bindingNote=A.T hook 3
TgeneKMT2Achr11:118353215chr11:118339488ENST00000354520+035169_1801443932DNA bindingNote=A.T hook 1
TgeneKMT2Achr11:118353215chr11:118339488ENST00000354520+035217_2271443932DNA bindingNote=A.T hook 2
TgeneKMT2Achr11:118353215chr11:118339488ENST00000354520+035301_3091443932DNA bindingNote=A.T hook 3
TgeneKMT2Achr11:118353215chr11:118339488ENST00000389506+036169_1801443970DNA bindingNote=A.T hook 1
TgeneKMT2Achr11:118353215chr11:118339488ENST00000389506+036217_2271443970DNA bindingNote=A.T hook 2
TgeneKMT2Achr11:118353215chr11:118339488ENST00000389506+036301_3091443970DNA bindingNote=A.T hook 3
TgeneKMT2Achr11:118353215chr11:118339488ENST00000534358+036169_1801443973DNA bindingNote=A.T hook 1
TgeneKMT2Achr11:118353215chr11:118339488ENST00000534358+036217_2271443973DNA bindingNote=A.T hook 2
TgeneKMT2Achr11:118353215chr11:118339488ENST00000534358+036301_3091443973DNA bindingNote=A.T hook 3
TgeneKMT2Achr11:118355030chr11:118339488ENST00000354520+035169_1801443932DNA bindingNote=A.T hook 1
TgeneKMT2Achr11:118355030chr11:118339488ENST00000354520+035217_2271443932DNA bindingNote=A.T hook 2
TgeneKMT2Achr11:118355030chr11:118339488ENST00000354520+035301_3091443932DNA bindingNote=A.T hook 3
TgeneKMT2Achr11:118355030chr11:118339488ENST00000389506+036169_1801443970DNA bindingNote=A.T hook 1
TgeneKMT2Achr11:118355030chr11:118339488ENST00000389506+036217_2271443970DNA bindingNote=A.T hook 2
TgeneKMT2Achr11:118355030chr11:118339488ENST00000389506+036301_3091443970DNA bindingNote=A.T hook 3
TgeneKMT2Achr11:118355030chr11:118339488ENST00000534358+036169_1801443973DNA bindingNote=A.T hook 1
TgeneKMT2Achr11:118355030chr11:118339488ENST00000534358+036217_2271443973DNA bindingNote=A.T hook 2
TgeneKMT2Achr11:118355030chr11:118339488ENST00000534358+036301_3091443973DNA bindingNote=A.T hook 3
TgeneKMT2Achr11:118350944chr11:118352667ENST00000354520+0351703_174803932DomainBromo%3B divergent
TgeneKMT2Achr11:118350944chr11:118352667ENST00000354520+0352018_207403932DomainFYR N-terminal
TgeneKMT2Achr11:118350944chr11:118352667ENST00000354520+0353666_374703932DomainFYR C-terminal
TgeneKMT2Achr11:118350944chr11:118352667ENST00000354520+0353829_394503932DomainSET
TgeneKMT2Achr11:118350944chr11:118352667ENST00000354520+0353953_396903932DomainPost-SET
TgeneKMT2Achr11:118350944chr11:118352667ENST00000389506+0361703_174803970DomainBromo%3B divergent
TgeneKMT2Achr11:118350944chr11:118352667ENST00000389506+0362018_207403970DomainFYR N-terminal
TgeneKMT2Achr11:118350944chr11:118352667ENST00000389506+0363666_374703970DomainFYR C-terminal
TgeneKMT2Achr11:118350944chr11:118352667ENST00000389506+0363829_394503970DomainSET
TgeneKMT2Achr11:118350944chr11:118352667ENST00000389506+0363953_396903970DomainPost-SET
TgeneKMT2Achr11:118350944chr11:118352667ENST00000534358+0361703_1748-83973DomainBromo%3B divergent
TgeneKMT2Achr11:118350944chr11:118352667ENST00000534358+0362018_2074-83973DomainFYR N-terminal
TgeneKMT2Achr11:118350944chr11:118352667ENST00000534358+0363666_3747-83973DomainFYR C-terminal
TgeneKMT2Achr11:118350944chr11:118352667ENST00000534358+0363829_3945-83973DomainSET
TgeneKMT2Achr11:118350944chr11:118352667ENST00000534358+0363953_3969-83973DomainPost-SET
TgeneKMT2Achr11:118353215chr11:118339488ENST00000354520+0351703_17481443932DomainBromo%3B divergent
TgeneKMT2Achr11:118353215chr11:118339488ENST00000354520+0352018_20741443932DomainFYR N-terminal
TgeneKMT2Achr11:118353215chr11:118339488ENST00000354520+0353666_37471443932DomainFYR C-terminal
TgeneKMT2Achr11:118353215chr11:118339488ENST00000354520+0353829_39451443932DomainSET
TgeneKMT2Achr11:118353215chr11:118339488ENST00000354520+0353953_39691443932DomainPost-SET
TgeneKMT2Achr11:118353215chr11:118339488ENST00000389506+0361703_17481443970DomainBromo%3B divergent
TgeneKMT2Achr11:118353215chr11:118339488ENST00000389506+0362018_20741443970DomainFYR N-terminal
TgeneKMT2Achr11:118353215chr11:118339488ENST00000389506+0363666_37471443970DomainFYR C-terminal
TgeneKMT2Achr11:118353215chr11:118339488ENST00000389506+0363829_39451443970DomainSET
TgeneKMT2Achr11:118353215chr11:118339488ENST00000389506+0363953_39691443970DomainPost-SET
TgeneKMT2Achr11:118353215chr11:118339488ENST00000534358+0361703_17481443973DomainBromo%3B divergent
TgeneKMT2Achr11:118353215chr11:118339488ENST00000534358+0362018_20741443973DomainFYR N-terminal
TgeneKMT2Achr11:118353215chr11:118339488ENST00000534358+0363666_37471443973DomainFYR C-terminal
TgeneKMT2Achr11:118353215chr11:118339488ENST00000534358+0363829_39451443973DomainSET
TgeneKMT2Achr11:118353215chr11:118339488ENST00000534358+0363953_39691443973DomainPost-SET
TgeneKMT2Achr11:118355030chr11:118339488ENST00000354520+0351703_17481443932DomainBromo%3B divergent
TgeneKMT2Achr11:118355030chr11:118339488ENST00000354520+0352018_20741443932DomainFYR N-terminal
TgeneKMT2Achr11:118355030chr11:118339488ENST00000354520+0353666_37471443932DomainFYR C-terminal
TgeneKMT2Achr11:118355030chr11:118339488ENST00000354520+0353829_39451443932DomainSET
TgeneKMT2Achr11:118355030chr11:118339488ENST00000354520+0353953_39691443932DomainPost-SET
TgeneKMT2Achr11:118355030chr11:118339488ENST00000389506+0361703_17481443970DomainBromo%3B divergent
TgeneKMT2Achr11:118355030chr11:118339488ENST00000389506+0362018_20741443970DomainFYR N-terminal
TgeneKMT2Achr11:118355030chr11:118339488ENST00000389506+0363666_37471443970DomainFYR C-terminal
TgeneKMT2Achr11:118355030chr11:118339488ENST00000389506+0363829_39451443970DomainSET
TgeneKMT2Achr11:118355030chr11:118339488ENST00000389506+0363953_39691443970DomainPost-SET
TgeneKMT2Achr11:118355030chr11:118339488ENST00000534358+0361703_17481443973DomainBromo%3B divergent
TgeneKMT2Achr11:118355030chr11:118339488ENST00000534358+0362018_20741443973DomainFYR N-terminal
TgeneKMT2Achr11:118355030chr11:118339488ENST00000534358+0363666_37471443973DomainFYR C-terminal
TgeneKMT2Achr11:118355030chr11:118339488ENST00000534358+0363829_39451443973DomainSET
TgeneKMT2Achr11:118355030chr11:118339488ENST00000534358+0363953_39691443973DomainPost-SET
TgeneKMT2Achr11:118350944chr11:118352667ENST00000354520+0353906_390703932RegionS-adenosyl-L-methionine binding
TgeneKMT2Achr11:118350944chr11:118352667ENST00000389506+0363906_390703970RegionS-adenosyl-L-methionine binding
TgeneKMT2Achr11:118350944chr11:118352667ENST00000534358+0363906_3907-83973RegionS-adenosyl-L-methionine binding
TgeneKMT2Achr11:118353215chr11:118339488ENST00000354520+0353906_39071443932RegionS-adenosyl-L-methionine binding
TgeneKMT2Achr11:118353215chr11:118339488ENST00000389506+0363906_39071443970RegionS-adenosyl-L-methionine binding
TgeneKMT2Achr11:118353215chr11:118339488ENST00000534358+0363906_39071443973RegionS-adenosyl-L-methionine binding
TgeneKMT2Achr11:118355030chr11:118339488ENST00000354520+0353906_39071443932RegionS-adenosyl-L-methionine binding
TgeneKMT2Achr11:118355030chr11:118339488ENST00000389506+0363906_39071443970RegionS-adenosyl-L-methionine binding
TgeneKMT2Achr11:118355030chr11:118339488ENST00000534358+0363906_39071443973RegionS-adenosyl-L-methionine binding
TgeneKMT2Achr11:118350944chr11:118352667ENST00000354520+0351147_119503932Zinc fingerCXXC-type
TgeneKMT2Achr11:118350944chr11:118352667ENST00000354520+0351431_148203932Zinc fingerPHD-type 1
TgeneKMT2Achr11:118350944chr11:118352667ENST00000354520+0351479_153303932Zinc fingerPHD-type 2
TgeneKMT2Achr11:118350944chr11:118352667ENST00000354520+0351566_162703932Zinc fingerPHD-type 3
TgeneKMT2Achr11:118350944chr11:118352667ENST00000354520+0351870_191003932Zinc fingerC2HC pre-PHD-type
TgeneKMT2Achr11:118350944chr11:118352667ENST00000354520+0351931_197803932Zinc fingerPHD-type 4
TgeneKMT2Achr11:118350944chr11:118352667ENST00000389506+0361147_119503970Zinc fingerCXXC-type
TgeneKMT2Achr11:118350944chr11:118352667ENST00000389506+0361431_148203970Zinc fingerPHD-type 1
TgeneKMT2Achr11:118350944chr11:118352667ENST00000389506+0361479_153303970Zinc fingerPHD-type 2
TgeneKMT2Achr11:118350944chr11:118352667ENST00000389506+0361566_162703970Zinc fingerPHD-type 3
TgeneKMT2Achr11:118350944chr11:118352667ENST00000389506+0361870_191003970Zinc fingerC2HC pre-PHD-type
TgeneKMT2Achr11:118350944chr11:118352667ENST00000389506+0361931_197803970Zinc fingerPHD-type 4
TgeneKMT2Achr11:118350944chr11:118352667ENST00000534358+0361147_1195-83973Zinc fingerCXXC-type
TgeneKMT2Achr11:118350944chr11:118352667ENST00000534358+0361431_1482-83973Zinc fingerPHD-type 1
TgeneKMT2Achr11:118350944chr11:118352667ENST00000534358+0361479_1533-83973Zinc fingerPHD-type 2
TgeneKMT2Achr11:118350944chr11:118352667ENST00000534358+0361566_1627-83973Zinc fingerPHD-type 3
TgeneKMT2Achr11:118350944chr11:118352667ENST00000534358+0361870_1910-83973Zinc fingerC2HC pre-PHD-type
TgeneKMT2Achr11:118350944chr11:118352667ENST00000534358+0361931_1978-83973Zinc fingerPHD-type 4
TgeneKMT2Achr11:118353215chr11:118339488ENST00000354520+0351147_11951443932Zinc fingerCXXC-type
TgeneKMT2Achr11:118353215chr11:118339488ENST00000354520+0351431_14821443932Zinc fingerPHD-type 1
TgeneKMT2Achr11:118353215chr11:118339488ENST00000354520+0351479_15331443932Zinc fingerPHD-type 2
TgeneKMT2Achr11:118353215chr11:118339488ENST00000354520+0351566_16271443932Zinc fingerPHD-type 3
TgeneKMT2Achr11:118353215chr11:118339488ENST00000354520+0351870_19101443932Zinc fingerC2HC pre-PHD-type
TgeneKMT2Achr11:118353215chr11:118339488ENST00000354520+0351931_19781443932Zinc fingerPHD-type 4
TgeneKMT2Achr11:118353215chr11:118339488ENST00000389506+0361147_11951443970Zinc fingerCXXC-type
TgeneKMT2Achr11:118353215chr11:118339488ENST00000389506+0361431_14821443970Zinc fingerPHD-type 1
TgeneKMT2Achr11:118353215chr11:118339488ENST00000389506+0361479_15331443970Zinc fingerPHD-type 2
TgeneKMT2Achr11:118353215chr11:118339488ENST00000389506+0361566_16271443970Zinc fingerPHD-type 3
TgeneKMT2Achr11:118353215chr11:118339488ENST00000389506+0361870_19101443970Zinc fingerC2HC pre-PHD-type
TgeneKMT2Achr11:118353215chr11:118339488ENST00000389506+0361931_19781443970Zinc fingerPHD-type 4
TgeneKMT2Achr11:118353215chr11:118339488ENST00000534358+0361147_11951443973Zinc fingerCXXC-type
TgeneKMT2Achr11:118353215chr11:118339488ENST00000534358+0361431_14821443973Zinc fingerPHD-type 1
TgeneKMT2Achr11:118353215chr11:118339488ENST00000534358+0361479_15331443973Zinc fingerPHD-type 2
TgeneKMT2Achr11:118353215chr11:118339488ENST00000534358+0361566_16271443973Zinc fingerPHD-type 3
TgeneKMT2Achr11:118353215chr11:118339488ENST00000534358+0361870_19101443973Zinc fingerC2HC pre-PHD-type
TgeneKMT2Achr11:118353215chr11:118339488ENST00000534358+0361931_19781443973Zinc fingerPHD-type 4
TgeneKMT2Achr11:118355030chr11:118339488ENST00000354520+0351147_11951443932Zinc fingerCXXC-type
TgeneKMT2Achr11:118355030chr11:118339488ENST00000354520+0351431_14821443932Zinc fingerPHD-type 1
TgeneKMT2Achr11:118355030chr11:118339488ENST00000354520+0351479_15331443932Zinc fingerPHD-type 2
TgeneKMT2Achr11:118355030chr11:118339488ENST00000354520+0351566_16271443932Zinc fingerPHD-type 3
TgeneKMT2Achr11:118355030chr11:118339488ENST00000354520+0351870_19101443932Zinc fingerC2HC pre-PHD-type
TgeneKMT2Achr11:118355030chr11:118339488ENST00000354520+0351931_19781443932Zinc fingerPHD-type 4
TgeneKMT2Achr11:118355030chr11:118339488ENST00000389506+0361147_11951443970Zinc fingerCXXC-type
TgeneKMT2Achr11:118355030chr11:118339488ENST00000389506+0361431_14821443970Zinc fingerPHD-type 1
TgeneKMT2Achr11:118355030chr11:118339488ENST00000389506+0361479_15331443970Zinc fingerPHD-type 2
TgeneKMT2Achr11:118355030chr11:118339488ENST00000389506+0361566_16271443970Zinc fingerPHD-type 3
TgeneKMT2Achr11:118355030chr11:118339488ENST00000389506+0361870_19101443970Zinc fingerC2HC pre-PHD-type
TgeneKMT2Achr11:118355030chr11:118339488ENST00000389506+0361931_19781443970Zinc fingerPHD-type 4
TgeneKMT2Achr11:118355030chr11:118339488ENST00000534358+0361147_11951443973Zinc fingerCXXC-type
TgeneKMT2Achr11:118355030chr11:118339488ENST00000534358+0361431_14821443973Zinc fingerPHD-type 1
TgeneKMT2Achr11:118355030chr11:118339488ENST00000534358+0361479_15331443973Zinc fingerPHD-type 2
TgeneKMT2Achr11:118355030chr11:118339488ENST00000534358+0361566_16271443973Zinc fingerPHD-type 3
TgeneKMT2Achr11:118355030chr11:118339488ENST00000534358+0361870_19101443973Zinc fingerC2HC pre-PHD-type
TgeneKMT2Achr11:118355030chr11:118339488ENST00000534358+0361931_19781443973Zinc fingerPHD-type 4

- In-frame and not-retained protein feature among the 13 regional features.
>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneKMT2Achr11:118350944chr11:118352667ENST00000354520+135137_14303932Compositional biasNote=Poly-Gly
HgeneKMT2Achr11:118350944chr11:118352667ENST00000354520+13517_10203932Compositional biasNote=Ala/Gly/Ser-rich
HgeneKMT2Achr11:118350944chr11:118352667ENST00000354520+135561_56403932Compositional biasNote=Poly-Pro
HgeneKMT2Achr11:118350944chr11:118352667ENST00000354520+135568_57103932Compositional biasNote=Poly-Pro
HgeneKMT2Achr11:118350944chr11:118352667ENST00000389506+136137_14303970Compositional biasNote=Poly-Gly
HgeneKMT2Achr11:118350944chr11:118352667ENST00000389506+13617_10203970Compositional biasNote=Ala/Gly/Ser-rich
HgeneKMT2Achr11:118350944chr11:118352667ENST00000389506+136561_56403970Compositional biasNote=Poly-Pro
HgeneKMT2Achr11:118350944chr11:118352667ENST00000389506+136568_57103970Compositional biasNote=Poly-Pro
HgeneKMT2Achr11:118350944chr11:118352667ENST00000534358+136137_143-83973Compositional biasNote=Poly-Gly
HgeneKMT2Achr11:118350944chr11:118352667ENST00000534358+13617_102-83973Compositional biasNote=Ala/Gly/Ser-rich
HgeneKMT2Achr11:118350944chr11:118352667ENST00000534358+136561_564-83973Compositional biasNote=Poly-Pro
HgeneKMT2Achr11:118350944chr11:118352667ENST00000534358+136568_571-83973Compositional biasNote=Poly-Pro
HgeneKMT2Achr11:118350944chr11:118352667ENST00000354520+135169_18003932DNA bindingNote=A.T hook 1
HgeneKMT2Achr11:118350944chr11:118352667ENST00000354520+135217_22703932DNA bindingNote=A.T hook 2
HgeneKMT2Achr11:118350944chr11:118352667ENST00000354520+135301_30903932DNA bindingNote=A.T hook 3
HgeneKMT2Achr11:118350944chr11:118352667ENST00000389506+136169_18003970DNA bindingNote=A.T hook 1
HgeneKMT2Achr11:118350944chr11:118352667ENST00000389506+136217_22703970DNA bindingNote=A.T hook 2
HgeneKMT2Achr11:118350944chr11:118352667ENST00000389506+136301_30903970DNA bindingNote=A.T hook 3
HgeneKMT2Achr11:118350944chr11:118352667ENST00000534358+136169_180-83973DNA bindingNote=A.T hook 1
HgeneKMT2Achr11:118350944chr11:118352667ENST00000534358+136217_227-83973DNA bindingNote=A.T hook 2
HgeneKMT2Achr11:118350944chr11:118352667ENST00000534358+136301_309-83973DNA bindingNote=A.T hook 3
HgeneKMT2Achr11:118350944chr11:118352667ENST00000354520+1351703_174803932DomainBromo%3B divergent
HgeneKMT2Achr11:118350944chr11:118352667ENST00000354520+1352018_207403932DomainFYR N-terminal
HgeneKMT2Achr11:118350944chr11:118352667ENST00000354520+1353666_374703932DomainFYR C-terminal
HgeneKMT2Achr11:118350944chr11:118352667ENST00000354520+1353829_394503932DomainSET
HgeneKMT2Achr11:118350944chr11:118352667ENST00000354520+1353953_396903932DomainPost-SET
HgeneKMT2Achr11:118350944chr11:118352667ENST00000389506+1361703_174803970DomainBromo%3B divergent
HgeneKMT2Achr11:118350944chr11:118352667ENST00000389506+1362018_207403970DomainFYR N-terminal
HgeneKMT2Achr11:118350944chr11:118352667ENST00000389506+1363666_374703970DomainFYR C-terminal
HgeneKMT2Achr11:118350944chr11:118352667ENST00000389506+1363829_394503970DomainSET
HgeneKMT2Achr11:118350944chr11:118352667ENST00000389506+1363953_396903970DomainPost-SET
HgeneKMT2Achr11:118350944chr11:118352667ENST00000534358+1361703_1748-83973DomainBromo%3B divergent
HgeneKMT2Achr11:118350944chr11:118352667ENST00000534358+1362018_2074-83973DomainFYR N-terminal
HgeneKMT2Achr11:118350944chr11:118352667ENST00000534358+1363666_3747-83973DomainFYR C-terminal
HgeneKMT2Achr11:118350944chr11:118352667ENST00000534358+1363829_3945-83973DomainSET
HgeneKMT2Achr11:118350944chr11:118352667ENST00000534358+1363953_3969-83973DomainPost-SET
HgeneKMT2Achr11:118353215chr11:118339488ENST00000354520+8351703_174813623932DomainBromo%3B divergent
HgeneKMT2Achr11:118353215chr11:118339488ENST00000354520+8352018_207413623932DomainFYR N-terminal
HgeneKMT2Achr11:118353215chr11:118339488ENST00000354520+8353666_374713623932DomainFYR C-terminal
HgeneKMT2Achr11:118353215chr11:118339488ENST00000354520+8353829_394513623932DomainSET
HgeneKMT2Achr11:118353215chr11:118339488ENST00000354520+8353953_396913623932DomainPost-SET
HgeneKMT2Achr11:118353215chr11:118339488ENST00000389506+8361703_174813623970DomainBromo%3B divergent
HgeneKMT2Achr11:118353215chr11:118339488ENST00000389506+8362018_207413623970DomainFYR N-terminal
HgeneKMT2Achr11:118353215chr11:118339488ENST00000389506+8363666_374713623970DomainFYR C-terminal
HgeneKMT2Achr11:118353215chr11:118339488ENST00000389506+8363829_394513623970DomainSET
HgeneKMT2Achr11:118353215chr11:118339488ENST00000389506+8363953_396913623970DomainPost-SET
HgeneKMT2Achr11:118353215chr11:118339488ENST00000534358+8361703_174813623973DomainBromo%3B divergent
HgeneKMT2Achr11:118353215chr11:118339488ENST00000534358+8362018_207413623973DomainFYR N-terminal
HgeneKMT2Achr11:118353215chr11:118339488ENST00000534358+8363666_374713623973DomainFYR C-terminal
HgeneKMT2Achr11:118353215chr11:118339488ENST00000534358+8363829_394513623973DomainSET
HgeneKMT2Achr11:118353215chr11:118339488ENST00000534358+8363953_396913623973DomainPost-SET
HgeneKMT2Achr11:118355030chr11:118339488ENST00000354520+9351703_174814063932DomainBromo%3B divergent
HgeneKMT2Achr11:118355030chr11:118339488ENST00000354520+9352018_207414063932DomainFYR N-terminal
HgeneKMT2Achr11:118355030chr11:118339488ENST00000354520+9353666_374714063932DomainFYR C-terminal
HgeneKMT2Achr11:118355030chr11:118339488ENST00000354520+9353829_394514063932DomainSET
HgeneKMT2Achr11:118355030chr11:118339488ENST00000354520+9353953_396914063932DomainPost-SET
HgeneKMT2Achr11:118355030chr11:118339488ENST00000389506+9361703_174814063970DomainBromo%3B divergent
HgeneKMT2Achr11:118355030chr11:118339488ENST00000389506+9362018_207414063970DomainFYR N-terminal
HgeneKMT2Achr11:118355030chr11:118339488ENST00000389506+9363666_374714063970DomainFYR C-terminal
HgeneKMT2Achr11:118355030chr11:118339488ENST00000389506+9363829_394514063970DomainSET
HgeneKMT2Achr11:118355030chr11:118339488ENST00000389506+9363953_396914063970DomainPost-SET
HgeneKMT2Achr11:118355030chr11:118339488ENST00000534358+9361703_174814063973DomainBromo%3B divergent
HgeneKMT2Achr11:118355030chr11:118339488ENST00000534358+9362018_207414063973DomainFYR N-terminal
HgeneKMT2Achr11:118355030chr11:118339488ENST00000534358+9363666_374714063973DomainFYR C-terminal
HgeneKMT2Achr11:118355030chr11:118339488ENST00000534358+9363829_394514063973DomainSET
HgeneKMT2Achr11:118355030chr11:118339488ENST00000534358+9363953_396914063973DomainPost-SET
HgeneKMT2Achr11:118350944chr11:118352667ENST00000354520+1353906_390703932RegionS-adenosyl-L-methionine binding
HgeneKMT2Achr11:118350944chr11:118352667ENST00000389506+1363906_390703970RegionS-adenosyl-L-methionine binding
HgeneKMT2Achr11:118350944chr11:118352667ENST00000534358+1363906_3907-83973RegionS-adenosyl-L-methionine binding
HgeneKMT2Achr11:118353215chr11:118339488ENST00000354520+8353906_390713623932RegionS-adenosyl-L-methionine binding
HgeneKMT2Achr11:118353215chr11:118339488ENST00000389506+8363906_390713623970RegionS-adenosyl-L-methionine binding
HgeneKMT2Achr11:118353215chr11:118339488ENST00000534358+8363906_390713623973RegionS-adenosyl-L-methionine binding
HgeneKMT2Achr11:118355030chr11:118339488ENST00000354520+9353906_390714063932RegionS-adenosyl-L-methionine binding
HgeneKMT2Achr11:118355030chr11:118339488ENST00000389506+9363906_390714063970RegionS-adenosyl-L-methionine binding
HgeneKMT2Achr11:118355030chr11:118339488ENST00000534358+9363906_390714063973RegionS-adenosyl-L-methionine binding
HgeneKMT2Achr11:118350944chr11:118352667ENST00000354520+1351147_119503932Zinc fingerCXXC-type
HgeneKMT2Achr11:118350944chr11:118352667ENST00000354520+1351431_148203932Zinc fingerPHD-type 1
HgeneKMT2Achr11:118350944chr11:118352667ENST00000354520+1351479_153303932Zinc fingerPHD-type 2
HgeneKMT2Achr11:118350944chr11:118352667ENST00000354520+1351566_162703932Zinc fingerPHD-type 3
HgeneKMT2Achr11:118350944chr11:118352667ENST00000354520+1351870_191003932Zinc fingerC2HC pre-PHD-type
HgeneKMT2Achr11:118350944chr11:118352667ENST00000354520+1351931_197803932Zinc fingerPHD-type 4
HgeneKMT2Achr11:118350944chr11:118352667ENST00000389506+1361147_119503970Zinc fingerCXXC-type
HgeneKMT2Achr11:118350944chr11:118352667ENST00000389506+1361431_148203970Zinc fingerPHD-type 1
HgeneKMT2Achr11:118350944chr11:118352667ENST00000389506+1361479_153303970Zinc fingerPHD-type 2
HgeneKMT2Achr11:118350944chr11:118352667ENST00000389506+1361566_162703970Zinc fingerPHD-type 3
HgeneKMT2Achr11:118350944chr11:118352667ENST00000389506+1361870_191003970Zinc fingerC2HC pre-PHD-type
HgeneKMT2Achr11:118350944chr11:118352667ENST00000389506+1361931_197803970Zinc fingerPHD-type 4
HgeneKMT2Achr11:118350944chr11:118352667ENST00000534358+1361147_1195-83973Zinc fingerCXXC-type
HgeneKMT2Achr11:118350944chr11:118352667ENST00000534358+1361431_1482-83973Zinc fingerPHD-type 1
HgeneKMT2Achr11:118350944chr11:118352667ENST00000534358+1361479_1533-83973Zinc fingerPHD-type 2
HgeneKMT2Achr11:118350944chr11:118352667ENST00000534358+1361566_1627-83973Zinc fingerPHD-type 3
HgeneKMT2Achr11:118350944chr11:118352667ENST00000534358+1361870_1910-83973Zinc fingerC2HC pre-PHD-type
HgeneKMT2Achr11:118350944chr11:118352667ENST00000534358+1361931_1978-83973Zinc fingerPHD-type 4
HgeneKMT2Achr11:118353215chr11:118339488ENST00000354520+8351431_148213623932Zinc fingerPHD-type 1
HgeneKMT2Achr11:118353215chr11:118339488ENST00000354520+8351479_153313623932Zinc fingerPHD-type 2
HgeneKMT2Achr11:118353215chr11:118339488ENST00000354520+8351566_162713623932Zinc fingerPHD-type 3
HgeneKMT2Achr11:118353215chr11:118339488ENST00000354520+8351870_191013623932Zinc fingerC2HC pre-PHD-type
HgeneKMT2Achr11:118353215chr11:118339488ENST00000354520+8351931_197813623932Zinc fingerPHD-type 4
HgeneKMT2Achr11:118353215chr11:118339488ENST00000389506+8361431_148213623970Zinc fingerPHD-type 1
HgeneKMT2Achr11:118353215chr11:118339488ENST00000389506+8361479_153313623970Zinc fingerPHD-type 2
HgeneKMT2Achr11:118353215chr11:118339488ENST00000389506+8361566_162713623970Zinc fingerPHD-type 3
HgeneKMT2Achr11:118353215chr11:118339488ENST00000389506+8361870_191013623970Zinc fingerC2HC pre-PHD-type
HgeneKMT2Achr11:118353215chr11:118339488ENST00000389506+8361931_197813623970Zinc fingerPHD-type 4
HgeneKMT2Achr11:118353215chr11:118339488ENST00000534358+8361431_148213623973Zinc fingerPHD-type 1
HgeneKMT2Achr11:118353215chr11:118339488ENST00000534358+8361479_153313623973Zinc fingerPHD-type 2
HgeneKMT2Achr11:118353215chr11:118339488ENST00000534358+8361566_162713623973Zinc fingerPHD-type 3
HgeneKMT2Achr11:118353215chr11:118339488ENST00000534358+8361870_191013623973Zinc fingerC2HC pre-PHD-type
HgeneKMT2Achr11:118353215chr11:118339488ENST00000534358+8361931_197813623973Zinc fingerPHD-type 4
HgeneKMT2Achr11:118355030chr11:118339488ENST00000354520+9351431_148214063932Zinc fingerPHD-type 1
HgeneKMT2Achr11:118355030chr11:118339488ENST00000354520+9351479_153314063932Zinc fingerPHD-type 2
HgeneKMT2Achr11:118355030chr11:118339488ENST00000354520+9351566_162714063932Zinc fingerPHD-type 3
HgeneKMT2Achr11:118355030chr11:118339488ENST00000354520+9351870_191014063932Zinc fingerC2HC pre-PHD-type
HgeneKMT2Achr11:118355030chr11:118339488ENST00000354520+9351931_197814063932Zinc fingerPHD-type 4
HgeneKMT2Achr11:118355030chr11:118339488ENST00000389506+9361431_148214063970Zinc fingerPHD-type 1
HgeneKMT2Achr11:118355030chr11:118339488ENST00000389506+9361479_153314063970Zinc fingerPHD-type 2
HgeneKMT2Achr11:118355030chr11:118339488ENST00000389506+9361566_162714063970Zinc fingerPHD-type 3
HgeneKMT2Achr11:118355030chr11:118339488ENST00000389506+9361870_191014063970Zinc fingerC2HC pre-PHD-type
HgeneKMT2Achr11:118355030chr11:118339488ENST00000389506+9361931_197814063970Zinc fingerPHD-type 4
HgeneKMT2Achr11:118355030chr11:118339488ENST00000534358+9361431_148214063973Zinc fingerPHD-type 1
HgeneKMT2Achr11:118355030chr11:118339488ENST00000534358+9361479_153314063973Zinc fingerPHD-type 2
HgeneKMT2Achr11:118355030chr11:118339488ENST00000534358+9361566_162714063973Zinc fingerPHD-type 3
HgeneKMT2Achr11:118355030chr11:118339488ENST00000534358+9361870_191014063973Zinc fingerC2HC pre-PHD-type
HgeneKMT2Achr11:118355030chr11:118339488ENST00000534358+9361931_197814063973Zinc fingerPHD-type 4
TgeneKMT2Achr11:118353215chr11:118339488ENST00000354520+035137_1431443932Compositional biasNote=Poly-Gly
TgeneKMT2Achr11:118353215chr11:118339488ENST00000354520+03517_1021443932Compositional biasNote=Ala/Gly/Ser-rich
TgeneKMT2Achr11:118353215chr11:118339488ENST00000389506+036137_1431443970Compositional biasNote=Poly-Gly
TgeneKMT2Achr11:118353215chr11:118339488ENST00000389506+03617_1021443970Compositional biasNote=Ala/Gly/Ser-rich
TgeneKMT2Achr11:118353215chr11:118339488ENST00000534358+036137_1431443973Compositional biasNote=Poly-Gly
TgeneKMT2Achr11:118353215chr11:118339488ENST00000534358+03617_1021443973Compositional biasNote=Ala/Gly/Ser-rich
TgeneKMT2Achr11:118355030chr11:118339488ENST00000354520+035137_1431443932Compositional biasNote=Poly-Gly
TgeneKMT2Achr11:118355030chr11:118339488ENST00000354520+03517_1021443932Compositional biasNote=Ala/Gly/Ser-rich
TgeneKMT2Achr11:118355030chr11:118339488ENST00000389506+036137_1431443970Compositional biasNote=Poly-Gly
TgeneKMT2Achr11:118355030chr11:118339488ENST00000389506+03617_1021443970Compositional biasNote=Ala/Gly/Ser-rich
TgeneKMT2Achr11:118355030chr11:118339488ENST00000534358+036137_1431443973Compositional biasNote=Poly-Gly
TgeneKMT2Achr11:118355030chr11:118339488ENST00000534358+03617_1021443973Compositional biasNote=Ala/Gly/Ser-rich


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FusionGeneSequence for KMT2A_KMT2A


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.

* Fusion transcript sequences (only coding sequence (CDS) region).

* Fusion transcript sequences (Full-length transcript).

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FusionGenePPI for KMT2A_KMT2A


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page

.

check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors
KMT2APPIE, PPP1R15A, KMT2A, ASH2L, HCFC1, HCFC2, MEN1, RBBP5, WDR5, AVP, INS, OXT, MAP3K5, HDAC1, CTBP1, CBX4, BMI1, CREBBP, SMARCB1, CXXC1, MYB, CTNNB1, SNW1, E2F2, E2F4, E2F6, PSIP1, MLLT4, POLR2A, KAT8, RNF2, TP53, SBF1, MTM1, SET, HIST1H3A, HIST1H4A, KAT6A, ELL, AFF1, AFF4, CDK9, CCNT1, CTR9, LEO1, PAF1, CDC73, WDR61, MLLT3, DOT1L, SKP2, HIST3H3, SVIL, HIST2H3C, SIN3A, MLLT1, RUNX1, CBFB, H3F3A, SIRT7, ASB2, TCEB1, TCEB2, CBX8, TOP1, TAF6, NCL, HECW2, LGR4, CSNK2A2, SENP3, SYMPK, PKN1, PIH1D1, KRAS, TAF1, CHD3, SMARCA2, SMARCC2, SMARCC1, HDAC2, RBBP4, RBBP7, TBP, MBD3, SAP30, RAN, TAF9, TASP1, HIST1H2BG, EWSR1, DYNLT1, KIF11, ING4, ZNF131, ASB7KMT2APPIE, PPP1R15A, KMT2A, ASH2L, HCFC1, HCFC2, MEN1, RBBP5, WDR5, AVP, INS, OXT, MAP3K5, HDAC1, CTBP1, CBX4, BMI1, CREBBP, SMARCB1, CXXC1, MYB, CTNNB1, SNW1, E2F2, E2F4, E2F6, PSIP1, MLLT4, POLR2A, KAT8, RNF2, TP53, SBF1, MTM1, SET, HIST1H3A, HIST1H4A, KAT6A, ELL, AFF1, AFF4, CDK9, CCNT1, CTR9, LEO1, PAF1, CDC73, WDR61, MLLT3, DOT1L, SKP2, HIST3H3, SVIL, HIST2H3C, SIN3A, MLLT1, RUNX1, CBFB, H3F3A, SIRT7, ASB2, TCEB1, TCEB2, CBX8, TOP1, TAF6, NCL, HECW2, LGR4, CSNK2A2, SENP3, SYMPK, PKN1, PIH1D1, KRAS, TAF1, CHD3, SMARCA2, SMARCC2, SMARCC1, HDAC2, RBBP4, RBBP7, TBP, MBD3, SAP30, RAN, TAF9, TASP1, HIST1H2BG, EWSR1, DYNLT1, KIF11, ING4, ZNF131, ASB7


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with
TgeneKMT2Achr11:118350944chr11:118352667ENST00000354520+0351584_160003932histone H3K4me3
TgeneKMT2Achr11:118350944chr11:118352667ENST00000389506+0361584_160003970histone H3K4me3
TgeneKMT2Achr11:118350944chr11:118352667ENST00000534358+0361584_1600-83973histone H3K4me3
TgeneKMT2Achr11:118353215chr11:118339488ENST00000354520+0351584_16001443932histone H3K4me3
TgeneKMT2Achr11:118353215chr11:118339488ENST00000389506+0361584_16001443970histone H3K4me3
TgeneKMT2Achr11:118353215chr11:118339488ENST00000534358+0361584_16001443973histone H3K4me3
TgeneKMT2Achr11:118355030chr11:118339488ENST00000354520+0351584_16001443932histone H3K4me3
TgeneKMT2Achr11:118355030chr11:118339488ENST00000389506+0361584_16001443970histone H3K4me3
TgeneKMT2Achr11:118355030chr11:118339488ENST00000534358+0361584_16001443973histone H3K4me3
TgeneKMT2Achr11:118350944chr11:118352667ENST00000354520+0353764_377103932WDR5
TgeneKMT2Achr11:118350944chr11:118352667ENST00000389506+0363764_377103970WDR5
TgeneKMT2Achr11:118350944chr11:118352667ENST00000534358+0363764_3771-83973WDR5
TgeneKMT2Achr11:118353215chr11:118339488ENST00000354520+0353764_37711443932WDR5
TgeneKMT2Achr11:118353215chr11:118339488ENST00000389506+0363764_37711443970WDR5
TgeneKMT2Achr11:118353215chr11:118339488ENST00000534358+0363764_37711443973WDR5
TgeneKMT2Achr11:118355030chr11:118339488ENST00000354520+0353764_37711443932WDR5
TgeneKMT2Achr11:118355030chr11:118339488ENST00000389506+0363764_37711443970WDR5
TgeneKMT2Achr11:118355030chr11:118339488ENST00000534358+0363764_37711443973WDR5


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
HgeneKMT2Achr11:118350944chr11:118352667ENST00000354520+1351584_160003932histone H3K4me3
HgeneKMT2Achr11:118350944chr11:118352667ENST00000389506+1361584_160003970histone H3K4me3
HgeneKMT2Achr11:118350944chr11:118352667ENST00000534358+1361584_1600-83973histone H3K4me3
HgeneKMT2Achr11:118353215chr11:118339488ENST00000354520+8351584_160013623932histone H3K4me3
HgeneKMT2Achr11:118353215chr11:118339488ENST00000389506+8361584_160013623970histone H3K4me3
HgeneKMT2Achr11:118353215chr11:118339488ENST00000534358+8361584_160013623973histone H3K4me3
HgeneKMT2Achr11:118355030chr11:118339488ENST00000354520+9351584_160014063932histone H3K4me3
HgeneKMT2Achr11:118355030chr11:118339488ENST00000389506+9361584_160014063970histone H3K4me3
HgeneKMT2Achr11:118355030chr11:118339488ENST00000534358+9361584_160014063973histone H3K4me3
HgeneKMT2Achr11:118350944chr11:118352667ENST00000354520+1353764_377103932WDR5
HgeneKMT2Achr11:118350944chr11:118352667ENST00000389506+1363764_377103970WDR5
HgeneKMT2Achr11:118350944chr11:118352667ENST00000534358+1363764_3771-83973WDR5
HgeneKMT2Achr11:118353215chr11:118339488ENST00000354520+8353764_377113623932WDR5
HgeneKMT2Achr11:118353215chr11:118339488ENST00000389506+8363764_377113623970WDR5
HgeneKMT2Achr11:118353215chr11:118339488ENST00000534358+8363764_377113623973WDR5
HgeneKMT2Achr11:118355030chr11:118339488ENST00000354520+9353764_377114063932WDR5
HgeneKMT2Achr11:118355030chr11:118339488ENST00000389506+9363764_377114063970WDR5
HgeneKMT2Achr11:118355030chr11:118339488ENST00000534358+9363764_377114063973WDR5


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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RelatedDrugs for KMT2A_KMT2A


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for KMT2A_KMT2A


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneKMT2AC0023418leukemia2CTD_human
HgeneKMT2AC0023467Leukemia, Myelocytic, Acute2CTD_human
HgeneKMT2AC0023470Myeloid Leukemia2CTD_human
HgeneKMT2AC1961102Precursor Cell Lymphoblastic Leukemia Lymphoma2CTD_human
HgeneKMT2AC0001418Adenocarcinoma1CTD_human
HgeneKMT2AC0005695Bladder Neoplasm1CTD_human
HgeneKMT2AC0007138Carcinoma, Transitional Cell1CTD_human
HgeneKMT2AC0008625Chromosome Aberrations1CTD_human
HgeneKMT2AC0023448Lymphoid leukemia1CTD_human
HgeneKMT2AC0023465Acute monocytic leukemia1CTD_human
HgeneKMT2AC0023479Acute myelomonocytic leukemia1CTD_human
HgeneKMT2AC0036341Schizophrenia1PSYGENET
HgeneKMT2AC0038356Stomach Neoplasms1CTD_human
HgeneKMT2AC0149925Small cell carcinoma of lung1CTD_human
HgeneKMT2AC2239176Liver carcinoma1CTD_human
TgeneKMT2AC0023418leukemia2CTD_human
TgeneKMT2AC0023467Leukemia, Myelocytic, Acute2CTD_human
TgeneKMT2AC0023470Myeloid Leukemia2CTD_human
TgeneKMT2AC1961102Precursor Cell Lymphoblastic Leukemia Lymphoma2CTD_human
TgeneKMT2AC0001418Adenocarcinoma1CTD_human
TgeneKMT2AC0005695Bladder Neoplasm1CTD_human
TgeneKMT2AC0007138Carcinoma, Transitional Cell1CTD_human
TgeneKMT2AC0008625Chromosome Aberrations1CTD_human
TgeneKMT2AC0023448Lymphoid leukemia1CTD_human
TgeneKMT2AC0023465Acute monocytic leukemia1CTD_human
TgeneKMT2AC0023479Acute myelomonocytic leukemia1CTD_human
TgeneKMT2AC0036341Schizophrenia1PSYGENET
TgeneKMT2AC0038356Stomach Neoplasms1CTD_human
TgeneKMT2AC0149925Small cell carcinoma of lung1CTD_human
TgeneKMT2AC2239176Liver carcinoma1CTD_human