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Fusion gene ID: 18890 |
FusionGeneSummary for KIF3A_PDLIM4 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: KIF3A_PDLIM4 | Fusion gene ID: 18890 | Hgene | Tgene | Gene symbol | KIF3A | PDLIM4 | Gene ID | 11127 | 8572 |
| Gene name | kinesin family member 3A | PDZ and LIM domain 4 | |
| Synonyms | FLA10|KLP-20 | RIL | |
| Cytomap | 5q31.1 | 5q31.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | kinesin-like protein KIF3Akinesin family protein 3Amicrotubule plus end-directed kinesin motor 3A | PDZ and LIM domain protein 4LIM domain proteinLIM protein RILenigma homologreversion-induced LIM protein | |
| Modification date | 20180527 | 20180519 | |
| UniProtAcc | Q9Y496 | P50479 | |
| Ensembl transtripts involved in fusion gene | ENST00000378746, ENST00000378735, ENST00000403231, ENST00000487055, | ENST00000253754, ENST00000379018, ENST00000484620, | |
| Fusion gene scores | * DoF score | 3 X 3 X 2=18 | 3 X 1 X 3=9 |
| # samples | 4 | 3 | |
| ** MAII score | log2(4/18*10)=1.15200309344505 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | log2(3/9*10)=1.73696559416621 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
| Context | PubMed: KIF3A [Title/Abstract] AND PDLIM4 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | Tumor suppressor gene involved fusion gene, in-frame but not retained their domain. Tumor suppressor gene involved fusion gene, retained protein feature but frameshift. DDR (DNA damage repair) gene involved fusion gene, in-frame but not retained their domain. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Tgene | PDLIM4 | GO:0031532 | actin cytoskeleton reorganization | 21636573 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | STAD | TCGA-HU-8238-01A | KIF3A | chr5 | 132073106 | - | PDLIM4 | chr5 | 131598302 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000378746 | ENST00000253754 | KIF3A | chr5 | 132073106 | - | PDLIM4 | chr5 | 131598302 | + |
| In-frame | ENST00000378746 | ENST00000379018 | KIF3A | chr5 | 132073106 | - | PDLIM4 | chr5 | 131598302 | + |
| 5CDS-intron | ENST00000378746 | ENST00000484620 | KIF3A | chr5 | 132073106 | - | PDLIM4 | chr5 | 131598302 | + |
| In-frame | ENST00000378735 | ENST00000253754 | KIF3A | chr5 | 132073106 | - | PDLIM4 | chr5 | 131598302 | + |
| In-frame | ENST00000378735 | ENST00000379018 | KIF3A | chr5 | 132073106 | - | PDLIM4 | chr5 | 131598302 | + |
| 5CDS-intron | ENST00000378735 | ENST00000484620 | KIF3A | chr5 | 132073106 | - | PDLIM4 | chr5 | 131598302 | + |
| In-frame | ENST00000403231 | ENST00000253754 | KIF3A | chr5 | 132073106 | - | PDLIM4 | chr5 | 131598302 | + |
| In-frame | ENST00000403231 | ENST00000379018 | KIF3A | chr5 | 132073106 | - | PDLIM4 | chr5 | 131598302 | + |
| 5CDS-intron | ENST00000403231 | ENST00000484620 | KIF3A | chr5 | 132073106 | - | PDLIM4 | chr5 | 131598302 | + |
| intron-3CDS | ENST00000487055 | ENST00000253754 | KIF3A | chr5 | 132073106 | - | PDLIM4 | chr5 | 131598302 | + |
| intron-3CDS | ENST00000487055 | ENST00000379018 | KIF3A | chr5 | 132073106 | - | PDLIM4 | chr5 | 131598302 | + |
| intron-intron | ENST00000487055 | ENST00000484620 | KIF3A | chr5 | 132073106 | - | PDLIM4 | chr5 | 131598302 | + |
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FusionProtFeatures for KIF3A_PDLIM4 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| KIF3A | PDLIM4 |
| Microtubule-based anterograde translocator formembranous organelles. Plus end-directed microtubule slidingactivity in vitro. Plays a role in primary cilia formation. Playsa role in centriole cohesion and subdistal appendage organizationand function. Regulates the formation of the subdistal appendagevia recruitement of DCTN1 to the centriole. Also required forciliary basal feet formation and microtubule anchoring to mothercentriole. {ECO:0000250|UniProtKB:P28741}. | Isoform 1: Suppresses SRC activation by recognizing andbinding to active SRC and facilitating PTPN13-mediateddephosphorylation of SRC 'Tyr-419' leading to its inactivation.Inactivated SRC dissociates from this protein allowing theinitiation of a new SRC inactivation cycle (PubMed:19307596).Involved in reorganization of the actin cytoskeleton(PubMed:21636573). In nonmuscle cells, binds to ACTN1 (alpha-actinin-1), increases the affinity of ACTN1 to F-actin(filamentous actin), and promotes formation of actin stressfibers. Involved in regulation of the synaptic AMPA receptortransport in dendritic spines of hippocampal pyramidal neuronsdirecting the receptors toward an insertion at the postsynapticmembrane. Links endosomal surface-internalized GRIA1-containingAMPA receptors to the alpha-actinin/actin cytoskeleton. IncreasesAMPA receptor-mediated excitatory postsynaptic currents in neurons(By similarity). {ECO:0000250|UniProtKB:P36202,ECO:0000269|PubMed:19307596, ECO:0000269|PubMed:21636573}. Isoform 2: Involved in reorganization of the actincytoskeleton and in regulation of cell migration. In response tooxidative stress, binds to NQO1, which stabilizes it and protectsit from ubiquitin-independent degradation by the core 20Sproteasome. Stabilized protein is able to heterodimerize withisoform 1 changing the subcellular location of it fromcytoskeleton and nuclei to cytosol, leading to loss of isoforms 1ability to induce formation of actin stress fibers. Counteractsthe effects produced by isoform 1 on organization of actincytoskeleton and cell motility to fine-tune actin cytoskeletonrearrangement and to attenuate cell migration.{ECO:0000269|PubMed:21636573}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | >PDLIM4 | chr5:132073106 | chr5:131598302 | ENST00000253754 | + | 0 | 7 | 253_312 | 31 | 331 | Domain | LIM zinc-binding |
| Tgene | >PDLIM4 | chr5:132073106 | chr5:131598302 | ENST00000379018 | + | 0 | 6 | 253_312 | 31 | 247 | Domain | LIM zinc-binding |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >KIF3A | chr5:132073106 | chr5:131598302 | ENST00000378746 | - | 1 | 17 | 355_590 | 2 | 700 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | >KIF3A | chr5:132073106 | chr5:131598302 | ENST00000378746 | - | 1 | 17 | 14_345 | 2 | 700 | Domain | Kinesin motor |
| Hgene | >KIF3A | chr5:132073106 | chr5:131598302 | ENST00000378746 | - | 1 | 17 | 100_107 | 2 | 700 | Nucleotide binding | ATP |
| Hgene | >KIF3A | chr5:132073106 | chr5:131598302 | ENST00000378746 | - | 1 | 17 | 697_699 | 2 | 700 | Region | Note=Globular |
| Tgene | PDLIM4 | chr5:132073106 | chr5:131598302 | ENST00000253754 | + | 0 | 7 | 1_84 | 31 | 331 | Domain | PDZ |
| Tgene | PDLIM4 | chr5:132073106 | chr5:131598302 | ENST00000379018 | + | 0 | 6 | 1_84 | 31 | 247 | Domain | PDZ |
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FusionGeneSequence for KIF3A_PDLIM4 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_KIF3A_ENST00000378746_chr5_132073106_-_PDLIM4_ENST00000253754_chr5_131598302_+_302aa MPVHAGSKAALAALCPGDLIQAINGESTELMTHLEAQNRIKGCHDHLTLSVSRPEGRSWPSAPDDSKAQAHRIHIDPEIQDGSPTTSRRP SGTGTGPEDGRPSLGSPYGQPPRFPVPHNGSSEATLPAQMSTLHVSPPPSADPARGLPRSRDCRVDLGSEVYRMLREPAEPVAAEPKQSG SFRYLQGMLEAGEGGDWPGPGGPRNLKPTASKLGAPLSGLQGLPECTRCGHGIVGTIVKARDKLYHPECFMCSDCGLNLKQRGYFFLDER >In-frame_KIF3A_ENST00000378746_chr5_132073106_-_PDLIM4_ENST00000379018_chr5_131598302_+_218aa MPVHAGSKAALAALCPGDLIQAINGESTELMTHLEAQNRIKGCHDHLTLSVSRPEGRSWPSAPDDSKAQAHRIHIDPEIQDGSPTTSRRP SGTGTGPEDGRPSLGSPYGQPPRFPVPHNGSSEATLPAQMSTLHVSPPPSADPARGLPRSRDCRVDLGSEVYRMLREPAEPVAAEPKQSG >In-frame_KIF3A_ENST00000378735_chr5_132073106_-_PDLIM4_ENST00000253754_chr5_131598302_+_302aa MPVHAGSKAALAALCPGDLIQAINGESTELMTHLEAQNRIKGCHDHLTLSVSRPEGRSWPSAPDDSKAQAHRIHIDPEIQDGSPTTSRRP SGTGTGPEDGRPSLGSPYGQPPRFPVPHNGSSEATLPAQMSTLHVSPPPSADPARGLPRSRDCRVDLGSEVYRMLREPAEPVAAEPKQSG SFRYLQGMLEAGEGGDWPGPGGPRNLKPTASKLGAPLSGLQGLPECTRCGHGIVGTIVKARDKLYHPECFMCSDCGLNLKQRGYFFLDER >In-frame_KIF3A_ENST00000378735_chr5_132073106_-_PDLIM4_ENST00000379018_chr5_131598302_+_218aa MPVHAGSKAALAALCPGDLIQAINGESTELMTHLEAQNRIKGCHDHLTLSVSRPEGRSWPSAPDDSKAQAHRIHIDPEIQDGSPTTSRRP SGTGTGPEDGRPSLGSPYGQPPRFPVPHNGSSEATLPAQMSTLHVSPPPSADPARGLPRSRDCRVDLGSEVYRMLREPAEPVAAEPKQSG >In-frame_KIF3A_ENST00000403231_chr5_132073106_-_PDLIM4_ENST00000253754_chr5_131598302_+_302aa MPVHAGSKAALAALCPGDLIQAINGESTELMTHLEAQNRIKGCHDHLTLSVSRPEGRSWPSAPDDSKAQAHRIHIDPEIQDGSPTTSRRP SGTGTGPEDGRPSLGSPYGQPPRFPVPHNGSSEATLPAQMSTLHVSPPPSADPARGLPRSRDCRVDLGSEVYRMLREPAEPVAAEPKQSG SFRYLQGMLEAGEGGDWPGPGGPRNLKPTASKLGAPLSGLQGLPECTRCGHGIVGTIVKARDKLYHPECFMCSDCGLNLKQRGYFFLDER >In-frame_KIF3A_ENST00000403231_chr5_132073106_-_PDLIM4_ENST00000379018_chr5_131598302_+_218aa MPVHAGSKAALAALCPGDLIQAINGESTELMTHLEAQNRIKGCHDHLTLSVSRPEGRSWPSAPDDSKAQAHRIHIDPEIQDGSPTTSRRP SGTGTGPEDGRPSLGSPYGQPPRFPVPHNGSSEATLPAQMSTLHVSPPPSADPARGLPRSRDCRVDLGSEVYRMLREPAEPVAAEPKQSG |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_KIF3A_ENST00000378746_chr5_132073106_-_PDLIM4_ENST00000253754_chr5_131598302_+_906nt ATGCCGGTCCATGCTGGCAGCAAGGCTGCATTGGCTGCCCTGTGCCCAGGAGACCTGATCCAGGCCATCAATGGTGAGAGCACAGAGCTC ATGACACACCTGGAGGCACAGAACCGCATCAAGGGCTGCCACGATCACCTCACACTGTCTGTGAGCAGGCCTGAGGGTAGGAGCTGGCCC AGTGCCCCTGATGACAGCAAGGCTCAGGCACACAGGATCCACATCGATCCTGAGATCCAGGACGGCAGCCCAACAACCAGCAGGCGGCCC TCAGGCACCGGGACTGGGCCAGAAGATGGCAGACCAAGCCTGGGATCTCCATATGGACAACCCCCTCGCTTTCCAGTCCCTCACAATGGC AGCAGCGAGGCCACCCTGCCAGCCCAGATGAGCACCCTGCATGTGTCTCCACCCCCCAGCGCTGACCCAGCCAGAGGCCTCCCGCGGAGC CGGGACTGCAGAGTCGACCTGGGCTCCGAGGTGTACAGGATGCTGCGGGAGCCAGCCGAGCCCGTGGCCGCGGAGCCCAAGCAGTCAGGC TCCTTCCGCTACTTGCAGGGCATGCTAGAGGCCGGCGAGGGCGGGGATTGGCCCGGGCCTGGCGGCCCCCGGAACCTCAAGCCCACGGCC AGCAAGCTGGGCGCTCCGCTGAGCGGCCTGCAGGGGCTGCCCGAGTGCACGCGCTGCGGCCACGGCATCGTGGGCACCATCGTCAAGGCA CGGGACAAGCTCTACCATCCCGAGTGCTTCATGTGCAGTGACTGCGGCCTGAACCTCAAGCAGCGTGGTTACTTCTTTCTGGACGAGCGG CTCTACTGTGAGAGCCACGCCAAGGCGCGCGTGAAGCCGCCCGAGGGCTACGACGTGGTGGCGGTGTACCCCAATGCCAAGGTGGAACTC >In-frame_KIF3A_ENST00000378746_chr5_132073106_-_PDLIM4_ENST00000379018_chr5_131598302_+_654nt ATGCCGGTCCATGCTGGCAGCAAGGCTGCATTGGCTGCCCTGTGCCCAGGAGACCTGATCCAGGCCATCAATGGTGAGAGCACAGAGCTC ATGACACACCTGGAGGCACAGAACCGCATCAAGGGCTGCCACGATCACCTCACACTGTCTGTGAGCAGGCCTGAGGGTAGGAGCTGGCCC AGTGCCCCTGATGACAGCAAGGCTCAGGCACACAGGATCCACATCGATCCTGAGATCCAGGACGGCAGCCCAACAACCAGCAGGCGGCCC TCAGGCACCGGGACTGGGCCAGAAGATGGCAGACCAAGCCTGGGATCTCCATATGGACAACCCCCTCGCTTTCCAGTCCCTCACAATGGC AGCAGCGAGGCCACCCTGCCAGCCCAGATGAGCACCCTGCATGTGTCTCCACCCCCCAGCGCTGACCCAGCCAGAGGCCTCCCGCGGAGC CGGGACTGCAGAGTCGACCTGGGCTCCGAGGTGTACAGGATGCTGCGGGAGCCAGCCGAGCCCGTGGCCGCGGAGCCCAAGCAGTCAGGC TCCTTCCGCTACTTGCAGGGCATGCTAGAGGCCGGCGAGGGCGGGGCACCATCGTCAAGGCACGGGACAAGCTCTACCATCCCGAGTGCT >In-frame_KIF3A_ENST00000378735_chr5_132073106_-_PDLIM4_ENST00000253754_chr5_131598302_+_906nt ATGCCGGTCCATGCTGGCAGCAAGGCTGCATTGGCTGCCCTGTGCCCAGGAGACCTGATCCAGGCCATCAATGGTGAGAGCACAGAGCTC ATGACACACCTGGAGGCACAGAACCGCATCAAGGGCTGCCACGATCACCTCACACTGTCTGTGAGCAGGCCTGAGGGTAGGAGCTGGCCC AGTGCCCCTGATGACAGCAAGGCTCAGGCACACAGGATCCACATCGATCCTGAGATCCAGGACGGCAGCCCAACAACCAGCAGGCGGCCC TCAGGCACCGGGACTGGGCCAGAAGATGGCAGACCAAGCCTGGGATCTCCATATGGACAACCCCCTCGCTTTCCAGTCCCTCACAATGGC AGCAGCGAGGCCACCCTGCCAGCCCAGATGAGCACCCTGCATGTGTCTCCACCCCCCAGCGCTGACCCAGCCAGAGGCCTCCCGCGGAGC CGGGACTGCAGAGTCGACCTGGGCTCCGAGGTGTACAGGATGCTGCGGGAGCCAGCCGAGCCCGTGGCCGCGGAGCCCAAGCAGTCAGGC TCCTTCCGCTACTTGCAGGGCATGCTAGAGGCCGGCGAGGGCGGGGATTGGCCCGGGCCTGGCGGCCCCCGGAACCTCAAGCCCACGGCC AGCAAGCTGGGCGCTCCGCTGAGCGGCCTGCAGGGGCTGCCCGAGTGCACGCGCTGCGGCCACGGCATCGTGGGCACCATCGTCAAGGCA CGGGACAAGCTCTACCATCCCGAGTGCTTCATGTGCAGTGACTGCGGCCTGAACCTCAAGCAGCGTGGTTACTTCTTTCTGGACGAGCGG CTCTACTGTGAGAGCCACGCCAAGGCGCGCGTGAAGCCGCCCGAGGGCTACGACGTGGTGGCGGTGTACCCCAATGCCAAGGTGGAACTC >In-frame_KIF3A_ENST00000378735_chr5_132073106_-_PDLIM4_ENST00000379018_chr5_131598302_+_654nt ATGCCGGTCCATGCTGGCAGCAAGGCTGCATTGGCTGCCCTGTGCCCAGGAGACCTGATCCAGGCCATCAATGGTGAGAGCACAGAGCTC ATGACACACCTGGAGGCACAGAACCGCATCAAGGGCTGCCACGATCACCTCACACTGTCTGTGAGCAGGCCTGAGGGTAGGAGCTGGCCC AGTGCCCCTGATGACAGCAAGGCTCAGGCACACAGGATCCACATCGATCCTGAGATCCAGGACGGCAGCCCAACAACCAGCAGGCGGCCC TCAGGCACCGGGACTGGGCCAGAAGATGGCAGACCAAGCCTGGGATCTCCATATGGACAACCCCCTCGCTTTCCAGTCCCTCACAATGGC AGCAGCGAGGCCACCCTGCCAGCCCAGATGAGCACCCTGCATGTGTCTCCACCCCCCAGCGCTGACCCAGCCAGAGGCCTCCCGCGGAGC CGGGACTGCAGAGTCGACCTGGGCTCCGAGGTGTACAGGATGCTGCGGGAGCCAGCCGAGCCCGTGGCCGCGGAGCCCAAGCAGTCAGGC TCCTTCCGCTACTTGCAGGGCATGCTAGAGGCCGGCGAGGGCGGGGCACCATCGTCAAGGCACGGGACAAGCTCTACCATCCCGAGTGCT >In-frame_KIF3A_ENST00000403231_chr5_132073106_-_PDLIM4_ENST00000253754_chr5_131598302_+_906nt ATGCCGGTCCATGCTGGCAGCAAGGCTGCATTGGCTGCCCTGTGCCCAGGAGACCTGATCCAGGCCATCAATGGTGAGAGCACAGAGCTC ATGACACACCTGGAGGCACAGAACCGCATCAAGGGCTGCCACGATCACCTCACACTGTCTGTGAGCAGGCCTGAGGGTAGGAGCTGGCCC AGTGCCCCTGATGACAGCAAGGCTCAGGCACACAGGATCCACATCGATCCTGAGATCCAGGACGGCAGCCCAACAACCAGCAGGCGGCCC TCAGGCACCGGGACTGGGCCAGAAGATGGCAGACCAAGCCTGGGATCTCCATATGGACAACCCCCTCGCTTTCCAGTCCCTCACAATGGC AGCAGCGAGGCCACCCTGCCAGCCCAGATGAGCACCCTGCATGTGTCTCCACCCCCCAGCGCTGACCCAGCCAGAGGCCTCCCGCGGAGC CGGGACTGCAGAGTCGACCTGGGCTCCGAGGTGTACAGGATGCTGCGGGAGCCAGCCGAGCCCGTGGCCGCGGAGCCCAAGCAGTCAGGC TCCTTCCGCTACTTGCAGGGCATGCTAGAGGCCGGCGAGGGCGGGGATTGGCCCGGGCCTGGCGGCCCCCGGAACCTCAAGCCCACGGCC AGCAAGCTGGGCGCTCCGCTGAGCGGCCTGCAGGGGCTGCCCGAGTGCACGCGCTGCGGCCACGGCATCGTGGGCACCATCGTCAAGGCA CGGGACAAGCTCTACCATCCCGAGTGCTTCATGTGCAGTGACTGCGGCCTGAACCTCAAGCAGCGTGGTTACTTCTTTCTGGACGAGCGG CTCTACTGTGAGAGCCACGCCAAGGCGCGCGTGAAGCCGCCCGAGGGCTACGACGTGGTGGCGGTGTACCCCAATGCCAAGGTGGAACTC >In-frame_KIF3A_ENST00000403231_chr5_132073106_-_PDLIM4_ENST00000379018_chr5_131598302_+_654nt ATGCCGGTCCATGCTGGCAGCAAGGCTGCATTGGCTGCCCTGTGCCCAGGAGACCTGATCCAGGCCATCAATGGTGAGAGCACAGAGCTC ATGACACACCTGGAGGCACAGAACCGCATCAAGGGCTGCCACGATCACCTCACACTGTCTGTGAGCAGGCCTGAGGGTAGGAGCTGGCCC AGTGCCCCTGATGACAGCAAGGCTCAGGCACACAGGATCCACATCGATCCTGAGATCCAGGACGGCAGCCCAACAACCAGCAGGCGGCCC TCAGGCACCGGGACTGGGCCAGAAGATGGCAGACCAAGCCTGGGATCTCCATATGGACAACCCCCTCGCTTTCCAGTCCCTCACAATGGC AGCAGCGAGGCCACCCTGCCAGCCCAGATGAGCACCCTGCATGTGTCTCCACCCCCCAGCGCTGACCCAGCCAGAGGCCTCCCGCGGAGC CGGGACTGCAGAGTCGACCTGGGCTCCGAGGTGTACAGGATGCTGCGGGAGCCAGCCGAGCCCGTGGCCGCGGAGCCCAAGCAGTCAGGC TCCTTCCGCTACTTGCAGGGCATGCTAGAGGCCGGCGAGGGCGGGGCACCATCGTCAAGGCACGGGACAAGCTCTACCATCCCGAGTGCT |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_KIF3A_ENST00000378746_chr5_132073106_-_PDLIM4_ENST00000253754_chr5_131598302_+_2350nt GCGCAGGCGTAATTCAAGGGCCGAGAGAGCCTGAGACTGGGCTTGGGGCGGGGCGAGCTCGGAATGCGGCTGCGCACTGGGCGCTCTCGC CCGAGAAGCCGCAGTCTCGAGAGCGTCAACGAGGTGTTTCGGTAGTCTCTGGCCATCCTTTCTGCGCACCCGGTGTCGCTGGGCTGCACC CCGGGCGGGGACGTCCGCCGGGCACGGGAGGGGGCCAAGATGCCGGTCCATGCTGGCAGCAAGGCTGCATTGGCTGCCCTGTGCCCAGGA GACCTGATCCAGGCCATCAATGGTGAGAGCACAGAGCTCATGACACACCTGGAGGCACAGAACCGCATCAAGGGCTGCCACGATCACCTC ACACTGTCTGTGAGCAGGCCTGAGGGTAGGAGCTGGCCCAGTGCCCCTGATGACAGCAAGGCTCAGGCACACAGGATCCACATCGATCCT GAGATCCAGGACGGCAGCCCAACAACCAGCAGGCGGCCCTCAGGCACCGGGACTGGGCCAGAAGATGGCAGACCAAGCCTGGGATCTCCA TATGGACAACCCCCTCGCTTTCCAGTCCCTCACAATGGCAGCAGCGAGGCCACCCTGCCAGCCCAGATGAGCACCCTGCATGTGTCTCCA CCCCCCAGCGCTGACCCAGCCAGAGGCCTCCCGCGGAGCCGGGACTGCAGAGTCGACCTGGGCTCCGAGGTGTACAGGATGCTGCGGGAG CCAGCCGAGCCCGTGGCCGCGGAGCCCAAGCAGTCAGGCTCCTTCCGCTACTTGCAGGGCATGCTAGAGGCCGGCGAGGGCGGGGATTGG CCCGGGCCTGGCGGCCCCCGGAACCTCAAGCCCACGGCCAGCAAGCTGGGCGCTCCGCTGAGCGGCCTGCAGGGGCTGCCCGAGTGCACG CGCTGCGGCCACGGCATCGTGGGCACCATCGTCAAGGCACGGGACAAGCTCTACCATCCCGAGTGCTTCATGTGCAGTGACTGCGGCCTG AACCTCAAGCAGCGTGGTTACTTCTTTCTGGACGAGCGGCTCTACTGTGAGAGCCACGCCAAGGCGCGCGTGAAGCCGCCCGAGGGCTAC GACGTGGTGGCGGTGTACCCCAATGCCAAGGTGGAACTCGTCTGAGCTGGGACCCTGCTCCCACGCCTGCTTCTTAAGGTCCCTGCTCGG CCGGTGTAAATATGTTTCACCCTGTCCCTCTAATAAAGCTCCTCTGCTCCACCTTGAACCTGTCACCTGGCCTGCCACCCTCCTGCGCAG GCCATGCATGGCTCCCGAGTACAGTAGTATCTGCTTAGGTGCCAGGCATGTCCTAGGCTCTGGGTGCAGTAGTGAGCAGGACGGGTACCA TGCTGCCCTGAAGGGGGCCACAGCCTGGGTGGAAGGCAGACCTGAATCACAACGGGCCAGCTCTAGTAATACGAAGGTGAGGTCTGGGAT GCTGCGTGCGGCGCGACGACAGGAGGTATGACCTGGGTGGGGTCAGGGAAAGTCTTAGCTGAGAACTAAGAGATGAGGGAGGCACAAACT CTGCACGGGGGAACTGTGTGTGCAAAGGTGAGCTGGGGGCGAGAAAGGCCTCTGTGGCCGTCATCGGCACTAGCGGGTTGGGGGTGGTGG TGGGGTGCTGGCAGCCTCAGGAGCGATCGCTCCCCTGGAGAGGGTGATTGAGTGTGGAGATCACCGGGGCCGCCGCGGGCCGTCTGCACT TCTGTTCCAGGTTTTTCTGGCATTTTCTGTTCCAGGTTTCTTCCACCCACGAGCACTTTATTCTCCTCCGAGACCCCCTTTTCTTCCCCT TCCTCTCTCCCCCACCAGGGGGCGCGCTTAAATTTCCAGACAGAGACCAGAAGGAAGGTTTAGAAAGAAAAGAACACTTGCCCAGGGCAG CTTTGCCCTCCAAGAGGCTCCCTCCTGTCTCTAAGTCAATTCCACCCCTCCTCGAAGTCCCGGCTTCCACCCCTCTCCTCAGAGTCCCGG CGTTTACCTCGTGGTGTGTTTGCCTTGGGCCTTTCATGCCCCGGCTGCACACATCGTCTGTGAATTGTGGCTGTTCACTCCCGAGGATGT GTCCTAGACTCCGGGTCGCGTGGATCTACCCTCTAGTTTACTTGCTCGGGAGAAGAAACTGACTCGTTTTATTTAGTGCCTATTTAGCGA GCCCAGAGTAACGTACATTTGTGCTGTTTTCAATTTTGTGCTATCGCAAATCACAAAAAAACTGTTATCAATTCACATTCATCATCAGCA CGAGACCCATTTCCTTGTGCTCCTGCCAGCTCAGGATATTATGTTTCTTTTTTCATTTTTGCCAGTCTGTTAAGTAAAATGTCATATGCG >In-frame_KIF3A_ENST00000378746_chr5_132073106_-_PDLIM4_ENST00000379018_chr5_131598302_+_1110nt GCGCAGGCGTAATTCAAGGGCCGAGAGAGCCTGAGACTGGGCTTGGGGCGGGGCGAGCTCGGAATGCGGCTGCGCACTGGGCGCTCTCGC CCGAGAAGCCGCAGTCTCGAGAGCGTCAACGAGGTGTTTCGGTAGTCTCTGGCCATCCTTTCTGCGCACCCGGTGTCGCTGGGCTGCACC CCGGGCGGGGACGTCCGCCGGGCACGGGAGGGGGCCAAGATGCCGGTCCATGCTGGCAGCAAGGCTGCATTGGCTGCCCTGTGCCCAGGA GACCTGATCCAGGCCATCAATGGTGAGAGCACAGAGCTCATGACACACCTGGAGGCACAGAACCGCATCAAGGGCTGCCACGATCACCTC ACACTGTCTGTGAGCAGGCCTGAGGGTAGGAGCTGGCCCAGTGCCCCTGATGACAGCAAGGCTCAGGCACACAGGATCCACATCGATCCT GAGATCCAGGACGGCAGCCCAACAACCAGCAGGCGGCCCTCAGGCACCGGGACTGGGCCAGAAGATGGCAGACCAAGCCTGGGATCTCCA TATGGACAACCCCCTCGCTTTCCAGTCCCTCACAATGGCAGCAGCGAGGCCACCCTGCCAGCCCAGATGAGCACCCTGCATGTGTCTCCA CCCCCCAGCGCTGACCCAGCCAGAGGCCTCCCGCGGAGCCGGGACTGCAGAGTCGACCTGGGCTCCGAGGTGTACAGGATGCTGCGGGAG CCAGCCGAGCCCGTGGCCGCGGAGCCCAAGCAGTCAGGCTCCTTCCGCTACTTGCAGGGCATGCTAGAGGCCGGCGAGGGCGGGGCACCA TCGTCAAGGCACGGGACAAGCTCTACCATCCCGAGTGCTTCATGTGCAGTGACTGCGGCCTGAACCTCAAGCAGCGTGGTTACTTCTTTC TGGACGAGCGGCTCTACTGTGAGAGCCACGCCAAGGCGCGCGTGAAGCCGCCCGAGGGCTACGACGTGGTGGCGGTGTACCCCAATGCCA AGGTGGAACTCGTCTGAGCTGGGACCCTGCTCCCACGCCTGCTTCTTAAGGTCCCTGCTCGGCCGGTGTAAATATGTTTCACCCTGTCCC >In-frame_KIF3A_ENST00000378735_chr5_132073106_-_PDLIM4_ENST00000253754_chr5_131598302_+_2284nt CGGCTGCGCACTGGGCGCTCTCGCCCGAGAAGCCGCAGTCTCGAGAGCGTCAACGAGGTGTTTCGGTAGTCTCTGGCCATCCTTTCTGCG CACCCGGTGTCGCTGGGCTGCACCCCGGGCGGGGACGTCCGCCGGGCACGGGAGGGGGCCAAGATGCCGGTCCATGCTGGCAGCAAGGCT GCATTGGCTGCCCTGTGCCCAGGAGACCTGATCCAGGCCATCAATGGTGAGAGCACAGAGCTCATGACACACCTGGAGGCACAGAACCGC ATCAAGGGCTGCCACGATCACCTCACACTGTCTGTGAGCAGGCCTGAGGGTAGGAGCTGGCCCAGTGCCCCTGATGACAGCAAGGCTCAG GCACACAGGATCCACATCGATCCTGAGATCCAGGACGGCAGCCCAACAACCAGCAGGCGGCCCTCAGGCACCGGGACTGGGCCAGAAGAT GGCAGACCAAGCCTGGGATCTCCATATGGACAACCCCCTCGCTTTCCAGTCCCTCACAATGGCAGCAGCGAGGCCACCCTGCCAGCCCAG ATGAGCACCCTGCATGTGTCTCCACCCCCCAGCGCTGACCCAGCCAGAGGCCTCCCGCGGAGCCGGGACTGCAGAGTCGACCTGGGCTCC GAGGTGTACAGGATGCTGCGGGAGCCAGCCGAGCCCGTGGCCGCGGAGCCCAAGCAGTCAGGCTCCTTCCGCTACTTGCAGGGCATGCTA GAGGCCGGCGAGGGCGGGGATTGGCCCGGGCCTGGCGGCCCCCGGAACCTCAAGCCCACGGCCAGCAAGCTGGGCGCTCCGCTGAGCGGC CTGCAGGGGCTGCCCGAGTGCACGCGCTGCGGCCACGGCATCGTGGGCACCATCGTCAAGGCACGGGACAAGCTCTACCATCCCGAGTGC TTCATGTGCAGTGACTGCGGCCTGAACCTCAAGCAGCGTGGTTACTTCTTTCTGGACGAGCGGCTCTACTGTGAGAGCCACGCCAAGGCG CGCGTGAAGCCGCCCGAGGGCTACGACGTGGTGGCGGTGTACCCCAATGCCAAGGTGGAACTCGTCTGAGCTGGGACCCTGCTCCCACGC CTGCTTCTTAAGGTCCCTGCTCGGCCGGTGTAAATATGTTTCACCCTGTCCCTCTAATAAAGCTCCTCTGCTCCACCTTGAACCTGTCAC CTGGCCTGCCACCCTCCTGCGCAGGCCATGCATGGCTCCCGAGTACAGTAGTATCTGCTTAGGTGCCAGGCATGTCCTAGGCTCTGGGTG CAGTAGTGAGCAGGACGGGTACCATGCTGCCCTGAAGGGGGCCACAGCCTGGGTGGAAGGCAGACCTGAATCACAACGGGCCAGCTCTAG TAATACGAAGGTGAGGTCTGGGATGCTGCGTGCGGCGCGACGACAGGAGGTATGACCTGGGTGGGGTCAGGGAAAGTCTTAGCTGAGAAC TAAGAGATGAGGGAGGCACAAACTCTGCACGGGGGAACTGTGTGTGCAAAGGTGAGCTGGGGGCGAGAAAGGCCTCTGTGGCCGTCATCG GCACTAGCGGGTTGGGGGTGGTGGTGGGGTGCTGGCAGCCTCAGGAGCGATCGCTCCCCTGGAGAGGGTGATTGAGTGTGGAGATCACCG GGGCCGCCGCGGGCCGTCTGCACTTCTGTTCCAGGTTTTTCTGGCATTTTCTGTTCCAGGTTTCTTCCACCCACGAGCACTTTATTCTCC TCCGAGACCCCCTTTTCTTCCCCTTCCTCTCTCCCCCACCAGGGGGCGCGCTTAAATTTCCAGACAGAGACCAGAAGGAAGGTTTAGAAA GAAAAGAACACTTGCCCAGGGCAGCTTTGCCCTCCAAGAGGCTCCCTCCTGTCTCTAAGTCAATTCCACCCCTCCTCGAAGTCCCGGCTT CCACCCCTCTCCTCAGAGTCCCGGCGTTTACCTCGTGGTGTGTTTGCCTTGGGCCTTTCATGCCCCGGCTGCACACATCGTCTGTGAATT GTGGCTGTTCACTCCCGAGGATGTGTCCTAGACTCCGGGTCGCGTGGATCTACCCTCTAGTTTACTTGCTCGGGAGAAGAAACTGACTCG TTTTATTTAGTGCCTATTTAGCGAGCCCAGAGTAACGTACATTTGTGCTGTTTTCAATTTTGTGCTATCGCAAATCACAAAAAAACTGTT ATCAATTCACATTCATCATCAGCACGAGACCCATTTCCTTGTGCTCCTGCCAGCTCAGGATATTATGTTTCTTTTTTCATTTTTGCCAGT >In-frame_KIF3A_ENST00000378735_chr5_132073106_-_PDLIM4_ENST00000379018_chr5_131598302_+_1044nt CGGCTGCGCACTGGGCGCTCTCGCCCGAGAAGCCGCAGTCTCGAGAGCGTCAACGAGGTGTTTCGGTAGTCTCTGGCCATCCTTTCTGCG CACCCGGTGTCGCTGGGCTGCACCCCGGGCGGGGACGTCCGCCGGGCACGGGAGGGGGCCAAGATGCCGGTCCATGCTGGCAGCAAGGCT GCATTGGCTGCCCTGTGCCCAGGAGACCTGATCCAGGCCATCAATGGTGAGAGCACAGAGCTCATGACACACCTGGAGGCACAGAACCGC ATCAAGGGCTGCCACGATCACCTCACACTGTCTGTGAGCAGGCCTGAGGGTAGGAGCTGGCCCAGTGCCCCTGATGACAGCAAGGCTCAG GCACACAGGATCCACATCGATCCTGAGATCCAGGACGGCAGCCCAACAACCAGCAGGCGGCCCTCAGGCACCGGGACTGGGCCAGAAGAT GGCAGACCAAGCCTGGGATCTCCATATGGACAACCCCCTCGCTTTCCAGTCCCTCACAATGGCAGCAGCGAGGCCACCCTGCCAGCCCAG ATGAGCACCCTGCATGTGTCTCCACCCCCCAGCGCTGACCCAGCCAGAGGCCTCCCGCGGAGCCGGGACTGCAGAGTCGACCTGGGCTCC GAGGTGTACAGGATGCTGCGGGAGCCAGCCGAGCCCGTGGCCGCGGAGCCCAAGCAGTCAGGCTCCTTCCGCTACTTGCAGGGCATGCTA GAGGCCGGCGAGGGCGGGGCACCATCGTCAAGGCACGGGACAAGCTCTACCATCCCGAGTGCTTCATGTGCAGTGACTGCGGCCTGAACC TCAAGCAGCGTGGTTACTTCTTTCTGGACGAGCGGCTCTACTGTGAGAGCCACGCCAAGGCGCGCGTGAAGCCGCCCGAGGGCTACGACG TGGTGGCGGTGTACCCCAATGCCAAGGTGGAACTCGTCTGAGCTGGGACCCTGCTCCCACGCCTGCTTCTTAAGGTCCCTGCTCGGCCGG >In-frame_KIF3A_ENST00000403231_chr5_132073106_-_PDLIM4_ENST00000253754_chr5_131598302_+_2131nt ATGCCGGTCCATGCTGGCAGCAAGGCTGCATTGGCTGCCCTGTGCCCAGGAGACCTGATCCAGGCCATCAATGGTGAGAGCACAGAGCTC ATGACACACCTGGAGGCACAGAACCGCATCAAGGGCTGCCACGATCACCTCACACTGTCTGTGAGCAGGCCTGAGGGTAGGAGCTGGCCC AGTGCCCCTGATGACAGCAAGGCTCAGGCACACAGGATCCACATCGATCCTGAGATCCAGGACGGCAGCCCAACAACCAGCAGGCGGCCC TCAGGCACCGGGACTGGGCCAGAAGATGGCAGACCAAGCCTGGGATCTCCATATGGACAACCCCCTCGCTTTCCAGTCCCTCACAATGGC AGCAGCGAGGCCACCCTGCCAGCCCAGATGAGCACCCTGCATGTGTCTCCACCCCCCAGCGCTGACCCAGCCAGAGGCCTCCCGCGGAGC CGGGACTGCAGAGTCGACCTGGGCTCCGAGGTGTACAGGATGCTGCGGGAGCCAGCCGAGCCCGTGGCCGCGGAGCCCAAGCAGTCAGGC TCCTTCCGCTACTTGCAGGGCATGCTAGAGGCCGGCGAGGGCGGGGATTGGCCCGGGCCTGGCGGCCCCCGGAACCTCAAGCCCACGGCC AGCAAGCTGGGCGCTCCGCTGAGCGGCCTGCAGGGGCTGCCCGAGTGCACGCGCTGCGGCCACGGCATCGTGGGCACCATCGTCAAGGCA CGGGACAAGCTCTACCATCCCGAGTGCTTCATGTGCAGTGACTGCGGCCTGAACCTCAAGCAGCGTGGTTACTTCTTTCTGGACGAGCGG CTCTACTGTGAGAGCCACGCCAAGGCGCGCGTGAAGCCGCCCGAGGGCTACGACGTGGTGGCGGTGTACCCCAATGCCAAGGTGGAACTC GTCTGAGCTGGGACCCTGCTCCCACGCCTGCTTCTTAAGGTCCCTGCTCGGCCGGTGTAAATATGTTTCACCCTGTCCCTCTAATAAAGC TCCTCTGCTCCACCTTGAACCTGTCACCTGGCCTGCCACCCTCCTGCGCAGGCCATGCATGGCTCCCGAGTACAGTAGTATCTGCTTAGG TGCCAGGCATGTCCTAGGCTCTGGGTGCAGTAGTGAGCAGGACGGGTACCATGCTGCCCTGAAGGGGGCCACAGCCTGGGTGGAAGGCAG ACCTGAATCACAACGGGCCAGCTCTAGTAATACGAAGGTGAGGTCTGGGATGCTGCGTGCGGCGCGACGACAGGAGGTATGACCTGGGTG GGGTCAGGGAAAGTCTTAGCTGAGAACTAAGAGATGAGGGAGGCACAAACTCTGCACGGGGGAACTGTGTGTGCAAAGGTGAGCTGGGGG CGAGAAAGGCCTCTGTGGCCGTCATCGGCACTAGCGGGTTGGGGGTGGTGGTGGGGTGCTGGCAGCCTCAGGAGCGATCGCTCCCCTGGA GAGGGTGATTGAGTGTGGAGATCACCGGGGCCGCCGCGGGCCGTCTGCACTTCTGTTCCAGGTTTTTCTGGCATTTTCTGTTCCAGGTTT CTTCCACCCACGAGCACTTTATTCTCCTCCGAGACCCCCTTTTCTTCCCCTTCCTCTCTCCCCCACCAGGGGGCGCGCTTAAATTTCCAG ACAGAGACCAGAAGGAAGGTTTAGAAAGAAAAGAACACTTGCCCAGGGCAGCTTTGCCCTCCAAGAGGCTCCCTCCTGTCTCTAAGTCAA TTCCACCCCTCCTCGAAGTCCCGGCTTCCACCCCTCTCCTCAGAGTCCCGGCGTTTACCTCGTGGTGTGTTTGCCTTGGGCCTTTCATGC CCCGGCTGCACACATCGTCTGTGAATTGTGGCTGTTCACTCCCGAGGATGTGTCCTAGACTCCGGGTCGCGTGGATCTACCCTCTAGTTT ACTTGCTCGGGAGAAGAAACTGACTCGTTTTATTTAGTGCCTATTTAGCGAGCCCAGAGTAACGTACATTTGTGCTGTTTTCAATTTTGT GCTATCGCAAATCACAAAAAAACTGTTATCAATTCACATTCATCATCAGCACGAGACCCATTTCCTTGTGCTCCTGCCAGCTCAGGATAT >In-frame_KIF3A_ENST00000403231_chr5_132073106_-_PDLIM4_ENST00000379018_chr5_131598302_+_891nt ATGCCGGTCCATGCTGGCAGCAAGGCTGCATTGGCTGCCCTGTGCCCAGGAGACCTGATCCAGGCCATCAATGGTGAGAGCACAGAGCTC ATGACACACCTGGAGGCACAGAACCGCATCAAGGGCTGCCACGATCACCTCACACTGTCTGTGAGCAGGCCTGAGGGTAGGAGCTGGCCC AGTGCCCCTGATGACAGCAAGGCTCAGGCACACAGGATCCACATCGATCCTGAGATCCAGGACGGCAGCCCAACAACCAGCAGGCGGCCC TCAGGCACCGGGACTGGGCCAGAAGATGGCAGACCAAGCCTGGGATCTCCATATGGACAACCCCCTCGCTTTCCAGTCCCTCACAATGGC AGCAGCGAGGCCACCCTGCCAGCCCAGATGAGCACCCTGCATGTGTCTCCACCCCCCAGCGCTGACCCAGCCAGAGGCCTCCCGCGGAGC CGGGACTGCAGAGTCGACCTGGGCTCCGAGGTGTACAGGATGCTGCGGGAGCCAGCCGAGCCCGTGGCCGCGGAGCCCAAGCAGTCAGGC TCCTTCCGCTACTTGCAGGGCATGCTAGAGGCCGGCGAGGGCGGGGCACCATCGTCAAGGCACGGGACAAGCTCTACCATCCCGAGTGCT TCATGTGCAGTGACTGCGGCCTGAACCTCAAGCAGCGTGGTTACTTCTTTCTGGACGAGCGGCTCTACTGTGAGAGCCACGCCAAGGCGC GCGTGAAGCCGCCCGAGGGCTACGACGTGGTGGCGGTGTACCCCAATGCCAAGGTGGAACTCGTCTGAGCTGGGACCCTGCTCCCACGCC |
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FusionGenePPI for KIF3A_PDLIM4 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| KIF3A | MAP3K10, MAP3K11, USP7, GRB2, PLEKHA5, DISC1, ARRB1, RANBP2, VHL, KIF3B, KIFAP3, NEK1, APP, LIG4, NOTCH1, CFTR, CASP1, OBFC1, DTNBP1, FASN, NTRK1, MED4, SCLT1, RAN, DHX34, GAK, KIF3C, RPA1, NUF2, CTNNBL1, FAM192A, SSH2, KIAA1279, H3F3B, TYW3, LYPLA2, HEPHL1, ATG9B, VSIG8, PKP3, DUSP14, EXOC3, PADI3, MFHAS1, HENMT1, SELENBP1, SSX2, LYG2, MAP1LC3B2, TRIM29, ZNF785, FAM26D, PLCD1, ALOX15B, APTX, RGS20, ACPP, TNFRSF8, ANXA8, ARL8A, PI4K2A, LRRC15, PREP, DSG4, SERPINB5, PKP1, HSDL2, DNPEP, XRCC4, DNAJC9, SSNA1, SLC9A3R2, CEP170, INTU | PDLIM4 | RBPMS, ZNF408, EWSR1, KIR3DL2, G3BP1 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for KIF3A_PDLIM4 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for KIF3A_PDLIM4 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | KIF3A | C0004096 | Asthma | 1 | CTD_human |
| Hgene | KIF3A | C0005941 | Bone Diseases, Developmental | 1 | CTD_human |
| Hgene | KIF3A | C0152427 | Polydactyly | 1 | CTD_human |
| Hgene | KIF3A | C0376634 | Craniofacial Abnormalities | 1 | CTD_human |
| Tgene | PDLIM4 | C0032460 | Polycystic Ovary Syndrome | 1 | CTD_human |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
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