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Fusion gene ID: 18784 |
FusionGeneSummary for KIF11_HIF1AN |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: KIF11_HIF1AN | Fusion gene ID: 18784 | Hgene | Tgene | Gene symbol | KIF11 | HIF1AN | Gene ID | 3832 | 55662 |
| Gene name | kinesin family member 11 | hypoxia inducible factor 1 subunit alpha inhibitor | |
| Synonyms | EG5|HKSP|KNSL1|MCLMR|TRIP5 | FIH1 | |
| Cytomap | 10q23.33 | 10q24.31 | |
| Type of gene | protein-coding | protein-coding | |
| Description | kinesin-like protein KIF11TR-interacting protein 5TRIP-5kinesin-like protein 1kinesin-like spindle protein HKSPkinesin-related motor protein Eg5thyroid receptor-interacting protein 5 | hypoxia-inducible factor 1-alpha inhibitorFIH-1factor inhibiting HIF-1factor inhibiting HIF1hypoxia inducible factor 1 alpha subunit inhibitorhypoxia-inducible factor asparagine hydroxylasepeptide-aspartate beta-dioxygenase | |
| Modification date | 20180527 | 20180523 | |
| UniProtAcc | P52732 | Q9NWT6 | |
| Ensembl transtripts involved in fusion gene | ENST00000260731, | ENST00000299163, ENST00000528044, | |
| Fusion gene scores | * DoF score | 4 X 4 X 4=64 | 3 X 2 X 3=18 |
| # samples | 4 | 3 | |
| ** MAII score | log2(4/64*10)=-0.678071905112638 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(3/18*10)=0.736965594166206 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
| Context | PubMed: KIF11 [Title/Abstract] AND HIF1AN [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | KIF11 | GO:0090307 | mitotic spindle assembly | 19001501 |
| Tgene | HIF1AN | GO:0036138 | peptidyl-histidine hydroxylation | 21251231 |
| Tgene | HIF1AN | GO:0042264 | peptidyl-aspartic acid hydroxylation | 21177872 |
| Tgene | HIF1AN | GO:0042265 | peptidyl-asparagine hydroxylation | 12080085|12215170|14734545|21177872 |
| Tgene | HIF1AN | GO:0045663 | positive regulation of myoblast differentiation | 18299578 |
| Tgene | HIF1AN | GO:0045746 | negative regulation of Notch signaling pathway | 18299578 |
| Tgene | HIF1AN | GO:0055114 | oxidation-reduction process | 12080085|12215170 |
| Tgene | HIF1AN | GO:0061428 | negative regulation of transcription from RNA polymerase II promoter in response to hypoxia | 11641274 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | SARC | TCGA-JV-A75J-01A | KIF11 | chr10 | 94376589 | + | HIF1AN | chr10 | 102296168 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000260731 | ENST00000299163 | KIF11 | chr10 | 94376589 | + | HIF1AN | chr10 | 102296168 | + |
| 5CDS-3UTR | ENST00000260731 | ENST00000528044 | KIF11 | chr10 | 94376589 | + | HIF1AN | chr10 | 102296168 | + |
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FusionProtFeatures for KIF11_HIF1AN |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| KIF11 | HIF1AN |
| Motor protein required for establishing a bipolarspindle during mitosis (PubMed:19001501). Required in non-mitoticcells for transport of secretory proteins from the Golgi complexto the cell surface (PubMed:23857769).{ECO:0000269|PubMed:19001501, ECO:0000269|PubMed:23857769}. | Hydroxylates HIF-1 alpha at 'Asn-803' in the C-terminaltransactivation domain (CAD). Functions as an oxygen sensor and,under normoxic conditions, the hydroxylation prevents interactionof HIF-1 with transcriptional coactivators including Cbp/p300-interacting transactivator. Involved in transcriptional repressionthrough interaction with HIF1A, VHL and histone deacetylases.Hydroxylates specific Asn residues within ankyrin repeat domains(ARD) of NFKB1, NFKBIA, NOTCH1, ASB4, PPP1R12A and several otherARD-containing proteins. Also hydroxylates Asp and His residueswithin ARDs of ANK1 and TNKS2, respectively. Negatively regulatesNOTCH1 activity, accelerating myogenic differentiation. Positivelyregulates ASB4 activity, promoting vascular differentiation.{ECO:0000269|PubMed:12042299, ECO:0000269|PubMed:12080085,ECO:0000269|PubMed:17003112, ECO:0000269|PubMed:17573339,ECO:0000269|PubMed:18299578, ECO:0000269|PubMed:19245366,ECO:0000269|PubMed:21177872, ECO:0000269|PubMed:21251231}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | KIF11 | chr10:94376589 | chr10:102296168 | ENST00000260731 | + | 9 | 22 | 18_359 | 376 | 1057 | Domain | Kinesin motor |
| Hgene | KIF11 | chr10:94376589 | chr10:102296168 | ENST00000260731 | + | 9 | 22 | 105_112 | 376 | 1057 | Nucleotide binding | ATP |
| Tgene | >HIF1AN | chr10:94376589 | chr10:102296168 | ENST00000299163 | + | 0 | 8 | 142_312 | 59 | 350 | Domain | JmjC |
| Tgene | >HIF1AN | chr10:94376589 | chr10:102296168 | ENST00000299163 | + | 0 | 8 | 181_183 | 59 | 350 | Region | Substrate binding |
| Tgene | >HIF1AN | chr10:94376589 | chr10:102296168 | ENST00000299163 | + | 0 | 8 | 201_203 | 59 | 350 | Region | Substrate binding |
| Tgene | >HIF1AN | chr10:94376589 | chr10:102296168 | ENST00000299163 | + | 0 | 8 | 238_239 | 59 | 350 | Region | Substrate binding |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >KIF11 | chr10:94376589 | chr10:102296168 | ENST00000260731 | + | 9 | 22 | 364_480 | 376 | 1057 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | >KIF11 | chr10:94376589 | chr10:102296168 | ENST00000260731 | + | 9 | 22 | 736_763 | 376 | 1057 | Coiled coil | Ontology_term=ECO:0000255 |
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FusionGeneSequence for KIF11_HIF1AN |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_KIF11_ENST00000260731_chr10_94376589_+_HIF1AN_ENST00000299163_chr10_102296168_+_667aa MASQPNSSAKKKEEKGKNIQVVVRCRPFNLAERKASAHSIVECDPVRKEVSVRTGGLADKSSRKTYTFDMVFGASTKQIDVYRSVVCPIL DEVIMGYNCTIFAYGQTGTGKTFTMEGERSPNEEYTWEEDPLAGIIPRTLHQIFEKLTDNGTEFSVKVSLLEIYNEELFDLLNPSSDVSE RLQMFDDPRNKRGVIIKGLEEITVHNKDEVYQILEKGAAKRTTAATLMNAYSSRSHSVFSVTIHMKETTIDGEELVKIGKLNLVDLAGSE NIGRSGAVDKRAREAGNINQSLLTLGRVITALVERTPHVPYRESKLTRILQDSLGGRTRTSIIATISPASLNLEETLSTLEYAHRAKNIL NKPEVNQKLTKKALIKEPVVLTDTNLVYPALKWDLEYLQENIGNGDFSVYSASTHKFLYYDEKKMANFQNFKPRSNREEMKFHEFVEKLQ DIQQRGGEERLYLQQTLNDTVGRKIVMDFLGFNWNWINKQQGKRGWGQLTSNLLLIGMEGNVTPAHYDEQQNFFAQIKGYKRCILFPPDQ FECLYPYPVHHPCDRQSQVDFDNPDYERFPNFQNVVGYETVVGPGDVLYIPMYWWHHIESLLNGGITITVNFWYKGAPTPKRIEYPLKAH |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_KIF11_ENST00000260731_chr10_94376589_+_HIF1AN_ENST00000299163_chr10_102296168_+_2001nt ATGGCGTCGCAGCCAAATTCGTCTGCGAAGAAGAAAGAGGAGAAGGGGAAGAACATCCAGGTGGTGGTGAGATGCAGACCATTTAATTTG GCAGAGCGGAAAGCTAGCGCCCATTCAATAGTAGAATGTGATCCTGTACGAAAAGAAGTTAGTGTACGAACTGGAGGATTGGCTGACAAG AGCTCAAGGAAAACATACACTTTTGATATGGTGTTTGGAGCATCTACTAAACAGATTGATGTTTACCGAAGTGTTGTTTGTCCAATTCTG GATGAAGTTATTATGGGCTATAATTGCACTATCTTTGCGTATGGCCAAACTGGCACTGGAAAAACTTTTACAATGGAAGGTGAAAGGTCA CCTAATGAAGAGTATACCTGGGAAGAGGATCCCTTGGCTGGTATAATTCCACGTACCCTTCATCAAATTTTTGAGAAACTTACTGATAAT GGTACTGAATTTTCAGTCAAAGTGTCTCTGTTGGAGATCTATAATGAAGAGCTTTTTGATCTTCTTAATCCATCATCTGATGTTTCTGAG AGACTACAGATGTTTGATGATCCCCGTAACAAGAGAGGAGTGATAATTAAAGGTTTAGAAGAAATTACAGTACACAACAAGGATGAAGTC TATCAAATTTTAGAAAAGGGGGCAGCAAAAAGGACAACTGCAGCTACTCTGATGAATGCATACTCTAGTCGTTCCCACTCAGTTTTCTCT GTTACAATACATATGAAAGAAACTACGATTGATGGAGAAGAGCTTGTTAAAATCGGAAAGTTGAACTTGGTTGATCTTGCAGGAAGTGAA AACATTGGCCGTTCTGGAGCTGTTGATAAGAGAGCTCGGGAAGCTGGAAATATAAATCAATCCCTGTTGACTTTGGGAAGGGTCATTACT GCCCTTGTAGAAAGAACACCTCATGTTCCTTATCGAGAATCTAAACTAACTAGAATCCTCCAGGATTCTCTTGGAGGGCGTACAAGAACA TCTATAATTGCAACAATTTCTCCTGCATCTCTCAATCTTGAGGAAACTCTGAGTACATTGGAATATGCTCATAGAGCAAAGAACATATTG AATAAGCCTGAAGTGAATCAGAAACTCACCAAAAAAGCTCTTATTAAGGAGCCTGTGGTGCTGACCGACACAAATCTTGTGTATCCTGCC CTGAAATGGGACCTTGAATACCTGCAAGAGAATATTGGCAATGGAGACTTCTCTGTGTACAGTGCCAGCACCCACAAGTTCTTGTACTAT GATGAGAAGAAGATGGCCAATTTCCAGAACTTTAAGCCGAGGTCCAACAGGGAAGAAATGAAATTTCATGAGTTCGTTGAGAAACTGCAG GATATACAGCAGCGAGGAGGGGAAGAGAGGTTGTATCTGCAGCAAACGCTCAATGACACTGTGGGCAGGAAGATTGTCATGGACTTCTTA GGTTTTAACTGGAACTGGATTAATAAGCAACAGGGAAAGCGTGGCTGGGGGCAGCTTACCTCTAACCTGCTGCTCATTGGCATGGAAGGA AATGTGACACCTGCTCACTATGATGAGCAGCAGAACTTTTTTGCTCAGATAAAAGGTTACAAACGATGCATCTTATTCCCTCCGGATCAG TTCGAGTGCCTCTACCCATACCCTGTTCATCACCCATGTGACAGACAGAGCCAGGTGGACTTTGACAATCCCGACTACGAGAGGTTCCCT AATTTCCAAAATGTGGTTGGTTACGAAACAGTGGTTGGCCCTGGTGATGTTCTTTACATCCCAATGTACTGGTGGCATCACATAGAGTCA TTACTAAATGGGGGGATTACCATCACTGTGAACTTCTGGTATAAGGGGGCTCCCACCCCTAAGAGAATTGAATATCCTCTCAAAGCTCAT CAGAAAGTGGCCATAATGAGAAACATTGAGAAGATGCTTGGAGAGGCCTTGGGGAACCCACAAGAGGTGGGGCCCTTGTTGAACACAATG |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_KIF11_ENST00000260731_chr10_94376589_+_HIF1AN_ENST00000299163_chr10_102296168_+_13952nt AGACTCCGGCCCCTGTCGGCCGCCAAGCCCCTCCGCCCCTCACAGCGCCCAGGTCCGCGGCCGGGCCTTGATTTTTTGGCGGGGACCGTC ATGGCGTCGCAGCCAAATTCGTCTGCGAAGAAGAAAGAGGAGAAGGGGAAGAACATCCAGGTGGTGGTGAGATGCAGACCATTTAATTTG GCAGAGCGGAAAGCTAGCGCCCATTCAATAGTAGAATGTGATCCTGTACGAAAAGAAGTTAGTGTACGAACTGGAGGATTGGCTGACAAG AGCTCAAGGAAAACATACACTTTTGATATGGTGTTTGGAGCATCTACTAAACAGATTGATGTTTACCGAAGTGTTGTTTGTCCAATTCTG GATGAAGTTATTATGGGCTATAATTGCACTATCTTTGCGTATGGCCAAACTGGCACTGGAAAAACTTTTACAATGGAAGGTGAAAGGTCA CCTAATGAAGAGTATACCTGGGAAGAGGATCCCTTGGCTGGTATAATTCCACGTACCCTTCATCAAATTTTTGAGAAACTTACTGATAAT GGTACTGAATTTTCAGTCAAAGTGTCTCTGTTGGAGATCTATAATGAAGAGCTTTTTGATCTTCTTAATCCATCATCTGATGTTTCTGAG AGACTACAGATGTTTGATGATCCCCGTAACAAGAGAGGAGTGATAATTAAAGGTTTAGAAGAAATTACAGTACACAACAAGGATGAAGTC TATCAAATTTTAGAAAAGGGGGCAGCAAAAAGGACAACTGCAGCTACTCTGATGAATGCATACTCTAGTCGTTCCCACTCAGTTTTCTCT GTTACAATACATATGAAAGAAACTACGATTGATGGAGAAGAGCTTGTTAAAATCGGAAAGTTGAACTTGGTTGATCTTGCAGGAAGTGAA AACATTGGCCGTTCTGGAGCTGTTGATAAGAGAGCTCGGGAAGCTGGAAATATAAATCAATCCCTGTTGACTTTGGGAAGGGTCATTACT GCCCTTGTAGAAAGAACACCTCATGTTCCTTATCGAGAATCTAAACTAACTAGAATCCTCCAGGATTCTCTTGGAGGGCGTACAAGAACA TCTATAATTGCAACAATTTCTCCTGCATCTCTCAATCTTGAGGAAACTCTGAGTACATTGGAATATGCTCATAGAGCAAAGAACATATTG AATAAGCCTGAAGTGAATCAGAAACTCACCAAAAAAGCTCTTATTAAGGAGCCTGTGGTGCTGACCGACACAAATCTTGTGTATCCTGCC CTGAAATGGGACCTTGAATACCTGCAAGAGAATATTGGCAATGGAGACTTCTCTGTGTACAGTGCCAGCACCCACAAGTTCTTGTACTAT GATGAGAAGAAGATGGCCAATTTCCAGAACTTTAAGCCGAGGTCCAACAGGGAAGAAATGAAATTTCATGAGTTCGTTGAGAAACTGCAG GATATACAGCAGCGAGGAGGGGAAGAGAGGTTGTATCTGCAGCAAACGCTCAATGACACTGTGGGCAGGAAGATTGTCATGGACTTCTTA GGTTTTAACTGGAACTGGATTAATAAGCAACAGGGAAAGCGTGGCTGGGGGCAGCTTACCTCTAACCTGCTGCTCATTGGCATGGAAGGA AATGTGACACCTGCTCACTATGATGAGCAGCAGAACTTTTTTGCTCAGATAAAAGGTTACAAACGATGCATCTTATTCCCTCCGGATCAG TTCGAGTGCCTCTACCCATACCCTGTTCATCACCCATGTGACAGACAGAGCCAGGTGGACTTTGACAATCCCGACTACGAGAGGTTCCCT AATTTCCAAAATGTGGTTGGTTACGAAACAGTGGTTGGCCCTGGTGATGTTCTTTACATCCCAATGTACTGGTGGCATCACATAGAGTCA TTACTAAATGGGGGGATTACCATCACTGTGAACTTCTGGTATAAGGGGGCTCCCACCCCTAAGAGAATTGAATATCCTCTCAAAGCTCAT CAGAAAGTGGCCATAATGAGAAACATTGAGAAGATGCTTGGAGAGGCCTTGGGGAACCCACAAGAGGTGGGGCCCTTGTTGAACACAATG ATCAAGGGCCGATACAACTAGCCTGCCAGGGGTCAAGGCCTCCTGCCAGGTGACTGCTATCCCGTCCACACCGCTTCATTGATGAGGACA GGAGACTCCAAGCGCTAGTATTGCACGCTGCACTTAATGGACTGGACTCTTGCCATGGCCCAGGAGTCAGGTGTTTGGAGCGAGGCAGGG CAGTTGGCACTCCACTCCTATTTGGAGGGACTTCATACCCTTGCCTCTTGTGCCCCAGCACCTTCTCTCTCTGCCCCCCGCCTAAAGTCC TGCATTCAGTGTGTGGAGTCCCAGCTTTTGGTTGTCATCATGTCTGTGTGTATGTTAGTCTGTCAACTTCGGAATGTGTGCGTGTGTGTG CATGCACACGCATGTATGTATCTGTTCCCTGTTCCTTCTGGGTCAGGCTGTCACTTCCGGCTCTCAGCCCTATCTCCTGCAACCTCAGTG CCTCAGCCTGAGAGAGAGATGAGATGCTCTTGGACTCCCCACTGCATCTGGGCTGCAGGGCCAGAGCTAGTCTGACCATTAGGTCAGTCT GCCTCCTGACAGTTTTTGCGTAGTCAAGCTCTAGGCGGTATGGGAATGGCTACCGGGACTCTAATGGGGTGAAAGAGAGGGGAGGCTTGC CTTTGAGAGCCTATATAGCCTTCCTGTGAGAGAGGATTAGATAGGGTTCCAACTGGGCCTACAAGCTCAAGCCATACATAAAAGGACCTT GGGACATAAGAACCAATGATTGTGCATAAGTTCTAAATTAGAGACACATATAGTTTCTCTCTTTCAGCACCAGCTCTTGCCCCTATGCTG GGTACCAAGGGAGTTCTCCTAGCTGTGGCTTCTCTAGGTTCTAGGGGTGCAAGCCTCTGTGTGTTTGTTTGTGTGTGTCTGTGTGTGCGT ATCCACACTAGGGGTGCAAGCCTCTGGGTGTGTGTGTGTGTGTGCGTGCGTGTGTGTGTGTGTGTCCGTGTGTGTGTGTGTGTGTGTCCA CACTGGCCAGCCTCCCTACTTACCAAGGTTCTCCACTGCTTACCTTTTCCAGTGGGACAGTACAGTGTGAGCCCCCGGGAAGTACTGCCT GACCTATCCTAAGCTTTTACACTTGGATTTTAGCCATCATATGTTGGCCAGGTCTCACTGCAGCCTGCCCGAGGCTAACTGGCTAGAGCC TCCAGGCCCTATGATGCTCCCTGCCCAGGCCATATCCTTTATTCCTGCTGAGCTTCCTGGCTGAATAGATGAAATGGGGTCAAGCCCAGG CAGCTCATTCACTACCTGTGATCCACCTCAGGGCACGGGCAAACACATAGGCTTGCGTCTTAAAGCCAGCTCCTCTGCCAGACCCCGTTG TAATGTGCCACAACACCCTCAATAGTCAGGGCAACTGGTGGAGCATGGAAGTCGAATTTCCTTTTCTGTTAGGAGCTACTCCTGGGAACC CCTCTCAGGGCTGCAGCTTACAGGTGGGCAGCTGTGATTGCACAACTTGAAGGGCCATCATTCACATCTATTCAGTGGGAGTGGGGTCCC TGGGATTGGGCAGTGTGGTGGCCCTGTGTCTCCTCACCTCTGCTCCTGTCTTCATCACCTTCTCTCTGGAAGGGAAGAGGAGTTGGAAGG TCTCTGGTTTTCTTTTCTTTTTTTTTTTTTTTGCCAAAGGTTTACTTCCAGCATCTGAGCTCTGGCTCTCACCCCTGAAGCTCAGTTATA GTGCACTGATGAACTGAGAGGATGCGTGTGGATGTGTGTGCATGCCTGAGTGCGTTTTTTGGGGAGGGGTGTTTATTTTTAGTACCCCAT TCTGGGGTTCTCTGATGCAGTGTGGATGTGAAGATATGGTACCTTCTCAAGTGTAGCTCTTTCAAATATAGTCAATGCTGGGAAATGTGA TTGCAGTGATCTCTATCTCTCCACTTCTTTTGGGAAAGAGGAGCACAGGAGCGGAGGAAAAACTTGGCCACAGTCACACTTGGAAAGATA GTAGATTATTTTCGTTCTCCTCAGCAGGTCTGCTGTATTCCTCGCTCAGCGCTCAAAGATGTGGGTGATGTGTCAAGGAGGCATGCACTC AGCTGGTCCTTGCTGAGTTATTTGCTGACACAGGTCTCACTAAGGTGGCTGAGGGGTGGGAGGGAGAAGGCTAATCTTGGAACCTTCACA GGATTGGCCTTGATCCTTGGGTAACACAAGAGTGATTCCTGATTTTTAGACACCTAATATGTGCCTAGTGCTTTTCTCTTTGTTCCTCAC TATCCTGCAAGGTAGGTATTCTCACTTACAGATGAATAAATGGGCTCAGAGAGATTAGGTGATTAGTGACAATCAGTTGTAACTTAGCAC TGTTAGGCTGCAAACCCCTTGCTCCTTCCTTTCCACCAAACTATGTTGATTTTCCTTCCTTACCTCCCTCCTTGTACCACAGGTTCTGTC CTCAAGATATCACCCCACTGGGCAGTATCTGAAGGCAGACCCAGCCCAAGATGGTGCAGAATATACAGCTCAGGGTGAAAGTTCTTCTGG GCTCCTGCTAACAAAGTCTTGGAAAAACTGCCTGGGAAGCCATATTATGAATTAGTGCTAGAAGAAGCTGTGGGGGGAACTGAGTTCTGT GTCTAATTGCATTACTTATGTGTCCTTGAATAGGACCCATAACTCCTCCCGGCATGCTTTTGCATCTATAGAACTGAAGCTGTAGTTCTA GATGGCACTAAGGGTCTTGGTTCATATTCAGCTGCTGCTTCCCCCCAAGGAAAAGATGAGGTTTTTCCCCTTCGATTACCTTTTGAGGGA TGTTTAGGCTCAAATTCTGCTTGCCACAGAGGAAACATTTCTGCTGTAGTTGTTTACCTCCATCCTAGCTGGCAGTGTGGGACACACACA TACAGCAAGTGAAGGTGGGGGTTTGGGCCTGTATAGAGGTCAGCTACGCTGCAGGCTCATCTATTCACACCAGCAGGTACAGAGAAAACT AGTGTTTTGTAAAGTCAAATATTTGTTGGGGGTTGGAGTTCTGGGGTTGGAGGAGGGGCTGTTCTGGGCATCAGTTGAGCAGATGCCCAG GATGCCTGGGGGAGACCAGCTTCCCCTACAAATCAGAGCTCTAAATTACAAGGTTTTTACCAACGTGAACAGTTGGGGGAAGTCGTCTGC TCTCATTTGCGTAATGGTTTCTGTCACTGGTGATTAGACACAGGATGAAGGAAAAGAAATTTGACAATTAGGAATGAGCGATCATTAATC TGAATCTGTTAGGAGACAGAGAGGGGAAGGATCCTTATCAGTGGGCCAGCCCAGTATGGGGAGACACTCCCTCCCTCTGCCCCCAGAGAC TCCTGGGCTACATCCTCTTTCAGTATTGCCACAAGTGGGCAGAGCTTGTATTTCTTAACAAAGATTAGGGACCCAGTTGCCAGCCTGAGA TGGATATAGGAACAGACATCTTTGGGCATGAGCCAACAAAGATAGAAATAGATGAGTGTCAGGTACAAGCTATAAGGCAAAGAATAACAG TGGAAAAGTTTTGACATGTGTTTGCCATTTGTGGAAAATGTTTTTGTAATAGTCAACACCCCTCATAGCCCACCTGTGACAAGTACTTGT TACATTCCAGCACTGTAGGGCGTGAGGAAAATCTGGTCCTTATCAAATCCCAGGAGCTTCTGCTTAGTTGGGGAAGAAATTACATGAAGC AACCAGAGGTTATAAGGCCACACTTGTATATCGTGCACCCTGTGTGGACAAGATTAGGGACTGTTGAGAGAGGAGGAAACCAGTAGAGAG CAAAGCTCTACCCAGGCTCCTTGTAAGCCTCTGGGCTCCCCCGAGAGGGCCTCGCTACTCTACGCTTCCTAGCAACGTTGATGTCCCCAC AACCCCACATCAGTGCAGCTGTGGCTGTGTGGAGGGGCTCTGAGGCCTCTGAGGCCAGATGTGTAAACAGTGCTGAGGTTCAGTAATAGG ATGAGTCTTCAGGTGTGGAGCAGCCCACCTTGGCTCTTCCCATGTCTCTGTGTTACTTCTCATATTCTGCTGTCCTTTCAAACTTCAAGG ACAGTATTAATTTATACTAGTATTTCTTCCTCAGTTTTGTGACTTGAATGCAGTGAGTGCCTTAGAGGATCCAAGGATGAAGGAATGCGG GTTGGTGGTTCTCTCTTTCAGAATGGGAACTTCCCAAAAATGGGGCTGCGTCTCGCCTCTCAGTAGGTTCCCTACCTCTGGGTCTTCCAC CCTTCAAAATCTGGTACAGAATTTAGCAGGGGCTGCAGGGAATGACCCTCAGGGACCAGTTTCACCCAGATGGGGTAGATGATGAGGTAT ACCTAGAAGTAGCTCAGGGCTCCAGAGTCTGGCCTTTCAGCTGGTGTCTTACTCCCCTTTGAGACCTTCAGCTGCTTGTCTTCCACTGCC TGCATACTTCTCTGATGTCTTCTCAAACTGTTGGCTCTAAAGGGATGTTCCAGCCTCCCTCTCCAGAGCTGCCTGCAGTTTCCCTTATTC AGCTGTCTCCTGCCTAGTCTCTCCAGCGGCCTCCTTACCAAGACCCTTTTTCCTAAACAGTTGTCCTTCCCTCAGAAACTCCATGGCTGC AAGTGTGAATAGACTTGTCTTTAGGATCCCTCTCTCTGGTCATCCCTGATCATCTTAGGGCCGTCTCCCTTTTCTGATTTTTGACAGCTC TGTTTATTTTGCCCATGGCTAGTCCTCTTGTTTTGTGTCTGCTGTGTGTTCTTGCCCTTCCATTGTCAGTTCTGTACATCCTGGTTCAGC TTGTCTCACTGTGGTAGCCCCTTCTGCTTGTCTTCAGCCATCTTGGTTTAATCCTCATAGGTCATGGATGAATGGAGCCTTGCTGAGCAC TTTGAGGGCATTTCTGTTGGGCACAACCTCAGAAACGGGAAGTCTTGAGGCCTGGGGGCGTGTGGTCAGTGAGGCCTCCAGAGGTGGGTT AGGGGTGGGCACCTACAAGGGCCAGTTGAGGGGAGAGGTGCAGGGATTGCTGAGGAGACTTTGTGAGAATGATGTCAGGCCCGGGAAGCT GGTGTGGAAGAACTGAGCTGTCAGAAGGAGATACCAATATCCCCTTTGCAGGGTGGTGATGGGCATCAAACATGACGTGGAACATGTCCC CTTCATGGAGGGTTTCCATCTAAATGCATCTGTGTGCCTTAGGGATCAGTAGTTCAGGGGTGGTGGACTTTTTTGAGTGTCTCCTAATTT CTCTGAGGTGTCTTTGGCTCTGTGTCACCAAATGTGCCTGACCTCTGCATCCCAGTGGTTGCTGAAAGGGAAACAGTATATTGCGTAGTC AGATGTCAGGAGTAGAGATCTTAATGAGAAAGGCCCTGGCAGCTGGAGAGATGAGAGGACCTAGTGGTCAGCTTATACCCAGACTATCTC TCCACTCCTCCAAGAGTTTGAGTCCCATAGCTGATGAAAGAATTTACATATGGGCTCCCCCCTGCTTTCCCACTGAAAATCTATTCTCAT ATTTTGGGAAGGAGCATATGTCCTTTAACTTTCAATGGTAAACAATCTAGGATAGTGTTTAAAGGCATGGATTTTGGAGTCACATATAGT TGGTTTGAATTTCTAGCTTCACTACTTACCAGCTGGGTTTGACCTTGGTTGATTTACTTAACCTCTCTGAGCCTCAGTTTCCTCAACTAT AATAACATGGGTGGAGGGAGGCATGTTGAAAATATCTACCTCAGGGTTGTTGGAATAACTGAAACAATGTTTGTAAAGCTTTAGCACAGT GCCTGGCAAGCACTTAATAAATGGCTGTGGTGGTGGTGGTTATATTTATTATGTGATTTATTCAGAAACTTGGTTTCAGTGATCTCTAAA CAGATTTCCAGTGGTTCTTTCTCTCTCAAGAAAAGCATAGGGAAAAACGAGAAACACCTTAGATAAACCATATTGAGTTGAGGGTAGACA GAAGAGTCTAGTACCTAAACTCACCCTAGAGGAAGAGAAACAGGAAGTGTCTTATGCCTCTTCTGCCTGGGCAGCCAGACTTTACTGCTG TACTACCAGCCCAGGGCCTTGGGTGAGAAGGTTTCAGGTCTGAGCTCCCCTTGCACTGTGTGAGAGGCCGTGGAGCCGAATGAGTCCTTA TTATACCTGGAGAAGCTGTTGTCTCCTCACACCATGAAATGTAATAGCAGTCAAATCAGGCCCCTCTTGATTCAATTTTAGTCCATGCCT TTCCATGTATTTAAATTATATAAGTGTTGGCCAGGTGTGGTGGCTCACACCTGTAATCCCAGCACTTCGGGAGGCTGAGGCAGGAGGATC ACTTGAGCCCAGGAGTTCGAACCAACCTTGGGCAGCATAGTGAGACCCCTTCTCTTAATAATTTTTTTTGAAAATAATTTTTTAAAAATT ACAAATATGGACCAGACACCTGGGAGGATTACCTCACGCCTGTAATCCCAGCACTTTGGGAGGCTGAGGTGGGTGGATCACCTGAGGTCA GGAGTTTGAGACTATCCTGGCCAACATGGTGAAACCCTGTCTCTACTAAAAATACAAAAATTAGCCAGATGTGGTGGTGGGTACCTGTAA TCCCAGCTACTCGGGAGGCTGAGACAGGAGAATCACTTGAACCTGGGAGGCGGAGGTTGCAGTGAGCTGAGATCACGTCATTGCACTCCA GCCTGGGTGACTACAGTGAGACTCCCTCTCAAAAAAAAAAAAAAAAAATTATGAGTATGTTAAGATTGTTCTAGGGGAGAAGGGCAATCA AAATTCAGAAAAATATGAGTGGGATGTTAATAGCTACCATTTGTTGAACACTTCTGTTCCAGGCACTGTATTAGTTCGTCCCCATGTGGT GCTCTCAGATCAGTAGGGGAGACAGGCAGGCAGTTAGAATTATGGTGTATAGAGGAGAAGCATTGCACTATGTCCAGTTTTTTATGGTAG GCTTCCTGCAGAAAGTGATAAGTCCAAGCTGATATGTGGAAGATGAATAATTAACCAGAGGTTGGGGGATTTCCCCCTTAGCTTCTCTTT CTTCCAGTCCAGCAGTCCAAAACAAACACTGCTTCCCAATGCCTAAGGGTTTTGTCGTACCTTACTCCAGGGAATGGGTGAGACAGTAGA TCCCAAGAAGAAAACCCTTTGGTTAGTCACAGAAATCTGAAAGTCTTGGTTGCTGGCTCAGATTTGTCCTGGAGTGGACGTAGATTGGAC TTGCTTATTTGTAGCCCTCCACCGTTCTCATTTGTGTTCTGGCCTCTGGAGCCACCCTGCCAGACCCTACTTGGAAGAAATGTTGAATCA AGCTACTCAGACTTCAGCCTGAGATGTATTATGGCTGGCTGGAATTCTCAGCCCTTTCCACATCATGATCCCATTAATCTCTTGGGTCTA TCCCCACGCCCAGCCACCTCTCCTCCTCACTATAAGCCAAGTCTCCCTGCAGTTCTCTATAAATACTCAGATCCTCTTGCCTCAGACCCT GGTCCCTAGCTTTGTGGGTGAAGAAGATACCTCTTTAGCTTGTGCCAACCCATCCCTCTGGGCTACAGGCCATTCTGTAGTCACCTTGCA GTCACGTCTTTCCTTCTAGATAACTGGCTCTGGGCCTTGGAAACCTTCTCTTTGGCTCTAGCTAATTTTGCTGTTTTATTCCGTTTACTT AAAACCTATTCACTTGGTCATTGAGGTCAGAACTATCAGGAAAGCTGTGCTCCTTAACCCATCATCTAAGCTAAGCTTGGGCCAGGTTTT TATTACCTCTTGAATATATATAGTGCAATATAGTGTAGTGGTTGAGAGTGGAGTCTGCATACCTGGATCTGCCATTCTGCATGACTTTGG GCAAATGGACAAACTGCCCGAAACTTGACTTGTTTATATGTATGGGGAAGACATCATTTACATTGTCAGGGTAAGGCTTAGCAGAATGAC CGGTCCATAGCAAGGGCTCAGTCTTTCTGTGTCTCTCAGTCTTTACCTCTCTTCCCCATCTAGCTTTCTGTCTAAGTTCCTGTTTCTAGT CTCAGGGCATATCTAGTTGTCAGCTCCTGAGCAGAGCAGAGGTATAAGTGTCAACTCATGCTTGTGTTACCAGTTCCTACCCCTGTCAGT AACCTCTGATGCTTACAAGGATACTATCACCTATGCCATCAGTGGGGAATGACCTTCCAAAAATATTTTTAACAATACTAAAAATACCTG AAACATACTGGGTGAAAATAAGACATTGGAGCTGCTGCTCCCCAAGGAGATAAAAGGACAGTTCCTAAAGAGGCATTGAAGGTTTGTATG AGCCAGCAGCACAGTCAGAAGGCAAGAAGGAGACCCTGGGATGTGCACAAGGATGCAGGAGACGAGATTGTCACAGAGGCTGTCATGCTA GTAAGAGTCAGAGGTTACTGATGGGTAGAGATTGTCAGAGTCTGCCTTGCTAGTCTAGAGGTAGGACCATGGATTTAAGAACGTTGCCTC CAAGTTTTTGAATTGTGAATTTTTGATCATATTTGAACAAAACCCCACCTACAGTCTGCATGGTCATTGTTCTCACAAGGGTTTGTGTGA TGCACTGACAAGAACAGAGGCTTTGGAGGTGACTCCTGGGTTTGAATCACCATTTGCCACTAGCTAATTCTAACCTTAGGTAAGTCAGTG TCTCTGGGTCTCAACCTCTTCCTCTGTGAGGGGTAGGAAATAGCACATAACTTGTAGCATTGTTATAAGGGCTCGTGATAATGTTTTTAA AACACCTGGCTCAAGCACTCAGGAAAATGTTTTATTATGAAGACCAAGTGTCTCTGAAAAGTGTTTCCTTAGTGTCTGGAGAGACTACAG CAGCAAGGCTTTTCTGATCCTACTCTGACTCTCAAGATAATGGTGCTTGAAGTGAAATCACAGAAGAGATGACTGGGGCAGGAAAAGCAA GATGGAAAAGATAAAGTTGTGGAAGGGACTGAAAGTCCATGAAGTGCTGGGCTGGGGACAGAAAGGGTTTAATAGGGCAGGGTCTTGAGG AACAGGAACAGAGACCTTGGTTCTGGGTTGCCATCTGATTCCCAGAAGAGTAAAGGAAATGGGGCAGGAGGATGTCTGTGGAGGACACAG TGTGGCTGAGTGGAGAGAACACAAGCTTCTGGCCAGTGAACCTAAGTGAGAATGTCAGTGGACTTTGCACAGGCTGGGTGCCTTTGGGGG TGTTCATCTCGCTATGCTTCGGTCCCCTCATTTAAAAAAATTGGTTAATAATATGATGACCTGCCAATGTGTGTGGAAATACTATGTAAA CTGAGCACTATATAAATGCTGGTTGTTGAGATATTGGGAGTGGGGGTTTCGGGAGATTTTGTTTGTTTGTTTTTTTGAGATGGAGTTTTC GCTCTTGTTGCCCAGGCTGGAGTGCAGTGGCGTGATCTTGGCTCACTGCAACCTCCACCTCCTCCAGGTTCAAGCAATTCTGCCTCAGCC TCCCGAGTAGCTGGGACTCAGGCGTGCGCCACCATGCCTGGCTAATTTTGTATTTTTAGTAGAGATGGGGTTTCTCCATGTTGGTCAGGC TGGTCTCGAACTCCCGACCTCAGGTGATCTGCCTGCCTTGGCCTCCCAAAGTGCTGGGATTACAGGTGCGAGCTACCACACCTGGCCCTG GATTTCTTAATAGGTCCTCTTATGTGGCTATTGAGAATGAATGAGACAACTCATTAACTAACTAAGTTAATTCAGAACTTAGTGCCTAGT AAGTGCTCAGTAAATGTTAGTTTCTTTTCCTCCATTTCTTCTTAGGAAGCATCGTTTACCCAGCATAAACAGGAGGACTCAACTGTGCAT GTCTTAGTGTGAACAAGTAACATCAGATTTCCCTTTTCTGAGGAGAGATCAGTTCTGTAAGAGGGAGCATGAGTGTGAATGGGGAAGAAT CATGGAGAAGGGAGCAGGACTCCACAGTACTGGAGATGGAGTAGGGACCTCTGGGAATCGTTGGCATGGGGGTGTGGTGCAGAAAGGGTG ATGCTAAGAGGTGAGAGTCTCAAGAAAGAAGATGGGTGTTCTAGAGGGGAAAGCTAAACGATGATAGGCAATGAGGAGCGGAGGACAAGA CCCTGAACTAAGGGTGAGGAGGCCAGCATTCTGTCAGGAGAACCTTAGGAATTGTGACCAGAAGTCAAAGTTGTTACAGCAATCCTGCAT TCAACCAGGTTTCATCTGAAAAACTTAAGAGTTGCTAGGCACAGTCGTGCACACTTGTAATCCCAACACTTTGGGAGGCTTGAGTCAGGA GGAAGCTTGAGGCCAGGAGTTTGAGATCAGCCTAGGCAGCATAGTGACACCCCATCTCTTGAAAAAACAAACACTCTTAAGAGCAGTGGT TCACCTAGAAATAAAAAGCAGAAATCATCAAGATGAGAAGACATTTTGTGTTTTGACAGCCAAGGAAATTTGCCACTGAGACAAGGTATC TGACAGCCTAGATGGGATTCTAGACTTCTGTGAGAAAGTGCAGTTAGGCCCTGAATAGCGTCAAACTCAGGGATGTGAGCTGACTGACTG CCTTTTTATGTAATGGAGGCCATGTGATAGGGCTTTATGAGGCCACAAATAGCACTTTCTGGGTCCTTTCACAGTCTAGTCAGTGGCCCA ACCAACATATCTGGTTGTTCTGCAATCTCAGTCATCTGAGAAGATAACCTCCAAAATACATGCAGTGGCATCAGGTGTTTCCTTGGTAGG TGTGCATCTTTTAATGATGGAGGACTTAGGATGAAGAACAGGTGTGTTTAAAAACATCAAACCCCCACATCATTACTATTTGCTGTAAGG ATCTATGCAGTTTGTATTTTAAGTCCTTGACATATGGAAGAGCATTTGTGAGAGTAACAGGTTTGCTTTGTAATGCCAACTAAAAAGTGT GTATTTATACTCGAATTTTAAGTTGAAATTTTGCTAAGTTTCTTTTTTTTTTTTTTGAGACGGAGTCTCACTCTGTTGCCCAGGCTGGAG TACAGTGGTACAATCATTGCTAAGTCTTTCTGTAGTTTTAGAACATTTAGAACAACTTAAGATTTCCTGTATTTATAAACTTAATTTATT GGAAATATAAGTACTTGATCAGGTTTTGTCTTGGTCAGATAAATTAAGTACTTAAGGAAATCAAATACATTAATCATATAAATGCCATTT AAGTGTTTAAAGGAGTTTAGTTAAATGTAAGTTGGATCAAACATTAAACTTTTTTGTTTTATAAGCAAAATAATAAGATTTGTTAGCAGA ACTTAAAAGCTTAGAAAAGAGAGGATTTTGGATATGTAACTTTGAAGAGGTGAATAGTTTGCTCTTTTCTGAGACAGGGCATTGCTTTTC GACGCAGGCTGGAGTGCAGTGGGGCAAGCATGGCTCACTGCAGCCTCAACCTCCTGGACTCAAGTGATCCTCCTGCCTCAGCCTCCCATG TAGCTGGGATCACAGGCACATGCCACCACACCTGGCTAATTTTTTATTTTTTGTAGAGACAGGGGCCTCACTTCATTGCCCAGGCGGATC TCGAACACCTGGGCTCAAGCAGTCCTGCCTCAGCCTCCCAAAGTTCTGGGATTACAGGCATAAGCCACTGTGCCTGGCCTTGAATATATT TTTTAACCAAAGTAATTTATGAATATAAATTGTTTCTATATAACCCAAAGTCACTCTCATTGACATTAAGAAACTCAGAGAGTGGGTTCT AAATGTAATATTACCACACACCCAAGTCACTTAGCCTCTACAAGTACCACGTAACTAGCAGCCGTTAAAAGATGGCCACCGCTAGTCCAG TCGGCCACAGACATGGTTTTGTTTGGCCAATACAAGTTTTTGAAAGTTTTAAAAAATTGACAACATTAAAGATCAGAAACTTGACCTAAA |
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FusionGenePPI for KIF11_HIF1AN |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| KIF11 | NCOR1, DCTN1, KIF11, TNFAIP3, RPAP1, MEPCE, MYSM1, KAT2B, ELAVL1, TRAF4, PINK1, CDK1, KIF5A, SMURF1, PEX14, PAN2, NPM1, FBXO6, RAPGEF2, PPARG, MLF1, CASP1, DNM3, TFDP3, C9orf41, C17orf59, WHSC1, PI4K2A, SNRNP70, NTRK1, MED4, SRPK2, ADARB2, AP2A2, ANK3, ANXA1, ANXA7, CALD1, CETN2, DECR1, ACSL3, FASN, H3F3A, HDLBP, TACC3, LAMB1, LDHA, MAP4, KMT2A, MYO1C, ORC2, PDE3A, PFKM, PRKCA, RPL23A, RPL28, RPL32, RPL36AL, RPL37A, RPS3A, RPS6, RPS23, SNRPD3, SUV39H1, TLN1, ZKSCAN8, LUZP1, BRPF1, HIST1H3A, DUSP11, EIF3A, EIF3I, NOLC1, MED14, TRIP4, CEP350, ILVBL, ANKLE2, KIAA0922, GTPBP4, EDC4, HSPB8, AP3M1, PNMA3, IRAK4, MRPL27, NOL7, NT5DC3, METTL13, ACSL5, ARID4B, H2BFS, PLEKHA5, DGCR8, RBM28, ZGRF1, PCID2, ACTR10, MTUS1, MLST8, SPATS2, PRR3, DYNLRB1, FLYWCH1, SPIRE2, CEP295, FAM122A, RBM45, DHRS13, ANKS6, C2orf69, DDX51, H3F3C, GAN, SNW1, CDC5L, YWHAZ, DPPA4, RC3H1, ATOH1, CRBN, RNF20, RNF40, SPERT, LINC01587, CYLD, BRCA1 | HIF1AN | ASB9, FBF1, ASB13, INVS, HIF1A, VHL, HDAC1, HDAC2, HDAC3, SIAH1, ASB4, OTUD7B, ELAVL1, UBE3A, HIF1AN, NFKB1, FEM1B, UACA, ASB5, ASB6, ASB7, ASB8, ASB16, ANKRD44, CLDN20, KLHL20, CCDC94, NFKBIA, ANKRD12, ANKRD55, NFKBIB, ANKDD1A, XPO1, OTUB1, APBA3, CASKIN1, ANKRD49, TNKS2, ANKRD27, FYCO1, NOTCH3, ANKRD52, RNASEL, ANKS1A, TNKS, USP24, RIPK4, RPRD2, TXLNG, PIP4K2B, REL, ANK3, OSBPL1A, PIP4K2C, C2orf44, ANKFY1, GMDS, TXLNA, MLLT4, NFKB2, EIF4ENIF1, ANK2, ASB10, ZFP36L2, KIAA1804, OSBPL3, ASB3, TBK1, HECTD1 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| Tgene | HIF1AN | chr10:94376589 | chr10:102296168 | ENST00000299163 | + | 0 | 8 | 2_125 | 59 | 350 | VHL |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for KIF11_HIF1AN |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for KIF11_HIF1AN |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | KIF11 | C0002938 | Aneuploidy | 1 | CTD_human |
| Hgene | KIF11 | C0027659 | Neoplasms, Experimental | 1 | CTD_human |
| Hgene | KIF11 | C1257806 | Chromosomal Instability | 1 | CTD_human |
| Hgene | KIF11 | C1835265 | Lymphedema, microcephaly and chorioretinopathy syndrome | 1 | ORPHANET;UNIPROT |
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