FusionGDB Logo

Home

Download

Statistics

Examples

Help

Contact
Center for Computational Systems Medicine
leaf

FusionGeneSummary

leaf

FusionProtFeature

leaf

FusionGeneSequence

leaf

FusionGenePPI

leaf

RelatedDrugs

leaf

RelatedDiseases

Fusion gene ID: 18781

FusionGeneSummary for KIDINS220_PINX1

check button Fusion gene summary
Fusion gene informationFusion gene name: KIDINS220_PINX1
Fusion gene ID: 18781
HgeneTgene
Gene symbol

KIDINS220

PINX1

Gene ID

57498

54984

Gene namekinase D interacting substrate 220PIN2 (TERF1) interacting telomerase inhibitor 1
SynonymsARMS|SINOGno1|LPTL|LPTS|Pxr1
Cytomap

2p25.1

8p23.1

Type of geneprotein-codingprotein-coding
Descriptionkinase D-interacting substrate of 220 kDaankyrin repeat-rich membrane-spanning proteinkinase D-interacting substrate 220kDaPIN2/TERF1-interacting telomerase inhibitor 167-11-3 proteinPIN2-interacting protein 1TRF1-interacting protein 1hepatocellular carcinoma-related putative tumor suppressorliver-related putative tumor suppressorpin2-interacting protein X1protein 67-1
Modification date2018052320180519
UniProtAcc

Q9ULH0

Q96BK5

Ensembl transtripts involved in fusion geneENST00000418530, ENST00000256707, 
ENST00000427284, ENST00000473731, 
ENST00000319688, ENST00000436566, 
ENST00000314787, ENST00000426190, 
ENST00000519088, ENST00000520018, 
Fusion gene scores* DoF score8 X 6 X 5=2404 X 3 X 3=36
# samples 63
** MAII scorelog2(6/240*10)=-2
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(3/36*10)=-0.263034405833794
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: KIDINS220 [Title/Abstract] AND PINX1 [Title/Abstract] AND fusion [Title/Abstract]

Functional or gene categories assigned by FusionGDB annotationTumor suppressor gene involved fusion gene, in-frame but not retained their domain.
Tumor suppressor gene involved fusion gene, retained protein feature but frameshift.
DDR (DNA damage repair) gene involved fusion gene, in-frame but not retained their domain.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgenePINX1

GO:0007004

telomere maintenance via telomerase

11701125

TgenePINX1

GO:0010972

negative regulation of G2/M transition of mitotic cell cycle

11701125

TgenePINX1

GO:0032211

negative regulation of telomere maintenance via telomerase

11701125

TgenePINX1

GO:0051974

negative regulation of telomerase activity

11701125

TgenePINX1

GO:1902570

protein localization to nucleolus

24415760

TgenePINX1

GO:1904744

positive regulation of telomeric DNA binding

19265708|24415760

TgenePINX1

GO:1904751

positive regulation of protein localization to nucleolus

19265708


check button Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
Data typeSourceCancer typeSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
TCGALDSARCTCGA-X6-A8C6-01AKIDINS220chr2

8890242

-PINX1chr8

10692285

-
* LD: Li Ding group's fusion gene list
  RV: Roel Verhaak group's fusion gene list
  ChiTaRs fusion database

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000418530ENST00000314787KIDINS220chr2

8890242

-PINX1chr8

10692285

-
In-frameENST00000418530ENST00000426190KIDINS220chr2

8890242

-PINX1chr8

10692285

-
In-frameENST00000418530ENST00000519088KIDINS220chr2

8890242

-PINX1chr8

10692285

-
5CDS-5UTRENST00000418530ENST00000520018KIDINS220chr2

8890242

-PINX1chr8

10692285

-
Frame-shiftENST00000256707ENST00000314787KIDINS220chr2

8890242

-PINX1chr8

10692285

-
Frame-shiftENST00000256707ENST00000426190KIDINS220chr2

8890242

-PINX1chr8

10692285

-
Frame-shiftENST00000256707ENST00000519088KIDINS220chr2

8890242

-PINX1chr8

10692285

-
5CDS-5UTRENST00000256707ENST00000520018KIDINS220chr2

8890242

-PINX1chr8

10692285

-
Frame-shiftENST00000427284ENST00000314787KIDINS220chr2

8890242

-PINX1chr8

10692285

-
Frame-shiftENST00000427284ENST00000426190KIDINS220chr2

8890242

-PINX1chr8

10692285

-
Frame-shiftENST00000427284ENST00000519088KIDINS220chr2

8890242

-PINX1chr8

10692285

-
5CDS-5UTRENST00000427284ENST00000520018KIDINS220chr2

8890242

-PINX1chr8

10692285

-
Frame-shiftENST00000473731ENST00000314787KIDINS220chr2

8890242

-PINX1chr8

10692285

-
Frame-shiftENST00000473731ENST00000426190KIDINS220chr2

8890242

-PINX1chr8

10692285

-
Frame-shiftENST00000473731ENST00000519088KIDINS220chr2

8890242

-PINX1chr8

10692285

-
5CDS-5UTRENST00000473731ENST00000520018KIDINS220chr2

8890242

-PINX1chr8

10692285

-
intron-3CDSENST00000319688ENST00000314787KIDINS220chr2

8890242

-PINX1chr8

10692285

-
intron-3CDSENST00000319688ENST00000426190KIDINS220chr2

8890242

-PINX1chr8

10692285

-
intron-3CDSENST00000319688ENST00000519088KIDINS220chr2

8890242

-PINX1chr8

10692285

-
intron-5UTRENST00000319688ENST00000520018KIDINS220chr2

8890242

-PINX1chr8

10692285

-
intron-3CDSENST00000436566ENST00000314787KIDINS220chr2

8890242

-PINX1chr8

10692285

-
intron-3CDSENST00000436566ENST00000426190KIDINS220chr2

8890242

-PINX1chr8

10692285

-
intron-3CDSENST00000436566ENST00000519088KIDINS220chr2

8890242

-PINX1chr8

10692285

-
intron-5UTRENST00000436566ENST00000520018KIDINS220chr2

8890242

-PINX1chr8

10692285

-

Top

FusionProtFeatures for KIDINS220_PINX1


check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
KIDINS220

Q9ULH0

PINX1

Q96BK5

Promotes a prolonged MAP-kinase signaling byneurotrophins through activation of a Rap1-dependent mechanism.Provides a docking site for the CRKL-C3G complex, resulting inRap1-dependent sustained ERK activation. May play an importantrole in regulating postsynaptic signal transduction through thesyntrophin-mediated localization of receptor tyrosine kinases suchas EPHA4. In cooperation with SNTA1 can enhance EPHA4-inducedJAK/STAT activation. Plays a role in nerve growth factor (NGF)-induced recruitment of RAPGEF2 to late endosomes and neuriteoutgrowth. May play a role in neurotrophin- and ephrin-mediatedneuronal outgrowth and in axon guidance during neural developmentand in neuronal regeneration (By similarity). Modulates stress-induced apoptosis of melanoma cells via regulation of the MEK/ERKsignaling pathway. {ECO:0000250, ECO:0000269|PubMed:18089783}. Microtubule-binding protein essential for faithfulchromosome segregation. Mediates TRF1 and TERT accumulation innucleolus and enhances TRF1 binding to telomeres. Inhibitstelomerase activity. May inhibit cell proliferation and act astumor suppressor. {ECO:0000269|PubMed:15381700,ECO:0000269|PubMed:17198684, ECO:0000269|PubMed:19117989,ECO:0000269|PubMed:19265708, ECO:0000269|PubMed:19393617,ECO:0000269|PubMed:19553660}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

.

* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000256707-2430440_95311381772DomainNote=KAP NTPase
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000418530-2428440_95310961673DomainNote=KAP NTPase
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000427284-2429440_95311381753DomainNote=KAP NTPase
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000473731-2429440_95311381753DomainNote=KAP NTPase
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000256707-2430103_13211381772RepeatNote=ANK 4
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000256707-2430136_16511381772RepeatNote=ANK 5
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000256707-2430169_19811381772RepeatNote=ANK 6
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000256707-2430202_23111381772RepeatNote=ANK 7
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000256707-2430235_26411381772RepeatNote=ANK 8
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000256707-2430268_29711381772RepeatNote=ANK 9
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000256707-2430301_33011381772RepeatNote=ANK 10
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000256707-2430334_36311381772RepeatNote=ANK 11
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000256707-2430367_39611381772RepeatNote=ANK 12
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000256707-243037_6611381772RepeatNote=ANK 2
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000256707-24304_3311381772RepeatNote=ANK 1
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000256707-243070_9911381772RepeatNote=ANK 3
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000418530-2428103_13210961673RepeatNote=ANK 4
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000418530-2428136_16510961673RepeatNote=ANK 5
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000418530-2428169_19810961673RepeatNote=ANK 6
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000418530-2428202_23110961673RepeatNote=ANK 7
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000418530-2428235_26410961673RepeatNote=ANK 8
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000418530-2428268_29710961673RepeatNote=ANK 9
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000418530-2428301_33010961673RepeatNote=ANK 10
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000418530-2428334_36310961673RepeatNote=ANK 11
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000418530-2428367_39610961673RepeatNote=ANK 12
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000418530-242837_6610961673RepeatNote=ANK 2
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000418530-24284_3310961673RepeatNote=ANK 1
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000418530-242870_9910961673RepeatNote=ANK 3
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000427284-2429103_13211381753RepeatNote=ANK 4
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000427284-2429136_16511381753RepeatNote=ANK 5
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000427284-2429169_19811381753RepeatNote=ANK 6
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000427284-2429202_23111381753RepeatNote=ANK 7
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000427284-2429235_26411381753RepeatNote=ANK 8
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000427284-2429268_29711381753RepeatNote=ANK 9
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000427284-2429301_33011381753RepeatNote=ANK 10
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000427284-2429334_36311381753RepeatNote=ANK 11
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000427284-2429367_39611381753RepeatNote=ANK 12
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000427284-242937_6611381753RepeatNote=ANK 2
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000427284-24294_3311381753RepeatNote=ANK 1
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000427284-242970_9911381753RepeatNote=ANK 3
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000473731-2429103_13211381753RepeatNote=ANK 4
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000473731-2429136_16511381753RepeatNote=ANK 5
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000473731-2429169_19811381753RepeatNote=ANK 6
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000473731-2429202_23111381753RepeatNote=ANK 7
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000473731-2429235_26411381753RepeatNote=ANK 8
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000473731-2429268_29711381753RepeatNote=ANK 9
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000473731-2429301_33011381753RepeatNote=ANK 10
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000473731-2429334_36311381753RepeatNote=ANK 11
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000473731-2429367_39611381753RepeatNote=ANK 12
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000473731-242937_6611381753RepeatNote=ANK 2
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000473731-24294_3311381753RepeatNote=ANK 1
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000473731-242970_9911381753RepeatNote=ANK 3
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000256707-24301_49911381772Topological domainCytoplasmic
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000256707-2430521_52411381772Topological domainExtracellular
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000256707-2430546_65911381772Topological domainCytoplasmic
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000256707-2430681_68511381772Topological domainExtracellular
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000418530-24281_49910961673Topological domainCytoplasmic
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000418530-2428521_52410961673Topological domainExtracellular
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000418530-2428546_65910961673Topological domainCytoplasmic
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000418530-2428681_68510961673Topological domainExtracellular
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000427284-24291_49911381753Topological domainCytoplasmic
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000427284-2429521_52411381753Topological domainExtracellular
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000427284-2429546_65911381753Topological domainCytoplasmic
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000427284-2429681_68511381753Topological domainExtracellular
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000473731-24291_49911381753Topological domainCytoplasmic
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000473731-2429521_52411381753Topological domainExtracellular
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000473731-2429546_65911381753Topological domainCytoplasmic
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000473731-2429681_68511381753Topological domainExtracellular
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000256707-2430500_52011381772TransmembraneHelical
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000256707-2430525_54511381772TransmembraneHelical
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000256707-2430660_68011381772TransmembraneHelical
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000256707-2430686_70611381772TransmembraneHelical
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000418530-2428500_52010961673TransmembraneHelical
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000418530-2428525_54510961673TransmembraneHelical
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000418530-2428660_68010961673TransmembraneHelical
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000418530-2428686_70610961673TransmembraneHelical
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000427284-2429500_52011381753TransmembraneHelical
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000427284-2429525_54511381753TransmembraneHelical
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000427284-2429660_68011381753TransmembraneHelical
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000427284-2429686_70611381753TransmembraneHelical
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000473731-2429500_52011381753TransmembraneHelical
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000473731-2429525_54511381753TransmembraneHelical
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000473731-2429660_68011381753TransmembraneHelical
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000473731-2429686_70611381753TransmembraneHelical
TgenePINX1chr2:8890242chr8:10692285ENST00000314787-0726_726329DomainG-patch
TgenePINX1chr2:8890242chr8:10692285ENST00000519088-0626_726175DomainG-patch
TgenePINX1chr2:8890242chr8:10692285ENST00000314787-07287_2976329MotifNote=TBM
TgenePINX1chr2:8890242chr8:10692285ENST00000519088-06287_2976175MotifNote=TBM
TgenePINX1chr2:8890242chr8:10692285ENST00000314787-07254_3286329RegionNote=Telomerase inhibitory domain (TID)
TgenePINX1chr2:8890242chr8:10692285ENST00000519088-06254_3286175RegionNote=Telomerase inhibitory domain (TID)

- In-frame and not-retained protein feature among the 13 regional features.
>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000319688-123440_953-531032DomainNote=KAP NTPase
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000256707-24301766_177111381772MotifPDZ-binding
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000319688-1231766_1771-531032MotifPDZ-binding
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000418530-24281766_177110961673MotifPDZ-binding
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000427284-24291766_177111381753MotifPDZ-binding
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000473731-24291766_177111381753MotifPDZ-binding
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000319688-123103_132-531032RepeatNote=ANK 4
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000319688-123136_165-531032RepeatNote=ANK 5
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000319688-123169_198-531032RepeatNote=ANK 6
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000319688-123202_231-531032RepeatNote=ANK 7
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000319688-123235_264-531032RepeatNote=ANK 8
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000319688-123268_297-531032RepeatNote=ANK 9
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000319688-123301_330-531032RepeatNote=ANK 10
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000319688-123334_363-531032RepeatNote=ANK 11
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000319688-123367_396-531032RepeatNote=ANK 12
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000319688-12337_66-531032RepeatNote=ANK 2
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000319688-1234_33-531032RepeatNote=ANK 1
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000319688-12370_99-531032RepeatNote=ANK 3
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000256707-2430707_177111381772Topological domainCytoplasmic
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000319688-1231_499-531032Topological domainCytoplasmic
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000319688-123521_524-531032Topological domainExtracellular
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000319688-123546_659-531032Topological domainCytoplasmic
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000319688-123681_685-531032Topological domainExtracellular
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000319688-123707_1771-531032Topological domainCytoplasmic
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000418530-2428707_177110961673Topological domainCytoplasmic
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000427284-2429707_177111381753Topological domainCytoplasmic
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000473731-2429707_177111381753Topological domainCytoplasmic
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000319688-123500_520-531032TransmembraneHelical
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000319688-123525_545-531032TransmembraneHelical
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000319688-123660_680-531032TransmembraneHelical
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000319688-123686_706-531032TransmembraneHelical


Top

FusionGeneSequence for KIDINS220_PINX1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.
>In-frame_KIDINS220_ENST00000418530_chr2_8890242_-_PINX1_ENST00000314787_chr8_10692285_-_1418aa
MIAAEQGNLEIVKELIKNGANCNLEDLDNWTALISASKEGHVHIVEELLKCGVNLEHRDMGGWTALMWACYKGRTDVVELLLSHGANPSV
TGLYSVYPIIWAAGRGHADIVHLLLQNGAKVNCSDKYGTTPLVWAARKGHLECVKHLLAMGADVDQEGANSMTALIVAVKGGYTQSVKEI
LKRNPNVNLTDKDGNTALMIASKEGHTEIVQDLLDAGTYVNIPDRSGDTVLIGAVRGGHVEIVRALLQKYADIDIRGQDNKTALYWAVEK
GNATMVRDILQCNPDTEICTKDGETPLIKATKMRNIEVVELLLDKGAKVSAVDKKGDTPLHIAIRGRSRKLAELLLRNPKDGRLLYRPNK
AGETPYNIDCSHQKSILTQIFGARHLSPTETDGDMLGYDLYSSALADILSEPTMQPPICVGLYAQWGSGKSFLLKKLEDEMKTFAGQQIE
PLFQFSWLIVFLTLLLCGGLGLLFAFTVHPNLGIAVSLSFLALLYIFFIVIYFGGRREGESWNWAWVLSTRLARHIGYLELLLKLMFVNP
PELPEQTTKALPVRFLFTDYNRLSSVGGETSLAEMIATLSDACEREFGFLATRLFRVFKTEDTQGKKKWKKTCCLPSFVIFLFIIGCIIS
GITLLAIFRVDPKHLTVNAVLISIASVVGLAFVLNCRTWWQVLDSLLNSQRKRLHNAASKLHKLKSEGFMKVLKCEVELMARMAKTIDSF
TQNQTRLVVIIDGLDACEQDKVLQMLDTVRVLFSKGPFIAIFASDPHIIIKAINQNLNSVLRDSNINGHDYMRNIVHLPVFLNSRGLSNA
RKFLVTSATNGDVPCSDTTGIQEDADRRVSQNSLGEMTKLGSKTALNRRDTYRRRQMQRTITRQMSFDLTKLLVTEDWFSDISPQTMRRL
LNIVSVTGRLLRANQISFNWDRLASWINLTEQWPYRTSWLILYLEETEGIPDQMTLKTIYERISKNIPTTKDVEPLLEIDGDIRNFEVFL
SSRTPVLVARDVKVFLPCTVNLDPKLREIIADVRAAREQISIGGLAYPPLPLHEGPPRAPSGYSQPPSVCSSTSFNGPFAGGVVSPQPHS
SYYSGMTGPQHPFYNRVGGSRSGLWILRTLPGVMTIPSLASGCXRRWGGLKERVXGLRSKEPQIILKFKXKITTWDSELPSIMKTTGLPI
RMILTSFWPNXTLAMGRKPQIPRTRRKRNLLALRKSPKSPKTVFTIXNSQKGRICHLGAKQILTAFLGKDRVRRLPRAMPVPPLQRRTKP
RQPAPSPSRSTLPSGWQHXRTSPRFQFQGLTFLRRRWNVKGGRKEIKRPQVKMWKVTSSLRPRGTRRESPRGPRPRSEWPRRRARQQKSS

>In-frame_KIDINS220_ENST00000418530_chr2_8890242_-_PINX1_ENST00000426190_chr8_10692285_-_1264aa
MIAAEQGNLEIVKELIKNGANCNLEDLDNWTALISASKEGHVHIVEELLKCGVNLEHRDMGGWTALMWACYKGRTDVVELLLSHGANPSV
TGLYSVYPIIWAAGRGHADIVHLLLQNGAKVNCSDKYGTTPLVWAARKGHLECVKHLLAMGADVDQEGANSMTALIVAVKGGYTQSVKEI
LKRNPNVNLTDKDGNTALMIASKEGHTEIVQDLLDAGTYVNIPDRSGDTVLIGAVRGGHVEIVRALLQKYADIDIRGQDNKTALYWAVEK
GNATMVRDILQCNPDTEICTKDGETPLIKATKMRNIEVVELLLDKGAKVSAVDKKGDTPLHIAIRGRSRKLAELLLRNPKDGRLLYRPNK
AGETPYNIDCSHQKSILTQIFGARHLSPTETDGDMLGYDLYSSALADILSEPTMQPPICVGLYAQWGSGKSFLLKKLEDEMKTFAGQQIE
PLFQFSWLIVFLTLLLCGGLGLLFAFTVHPNLGIAVSLSFLALLYIFFIVIYFGGRREGESWNWAWVLSTRLARHIGYLELLLKLMFVNP
PELPEQTTKALPVRFLFTDYNRLSSVGGETSLAEMIATLSDACEREFGFLATRLFRVFKTEDTQGKKKWKKTCCLPSFVIFLFIIGCIIS
GITLLAIFRVDPKHLTVNAVLISIASVVGLAFVLNCRTWWQVLDSLLNSQRKRLHNAASKLHKLKSEGFMKVLKCEVELMARMAKTIDSF
TQNQTRLVVIIDGLDACEQDKVLQMLDTVRVLFSKGPFIAIFASDPHIIIKAINQNLNSVLRDSNINGHDYMRNIVHLPVFLNSRGLSNA
RKFLVTSATNGDVPCSDTTGIQEDADRRVSQNSLGEMTKLGSKTALNRRDTYRRRQMQRTITRQMSFDLTKLLVTEDWFSDISPQTMRRL
LNIVSVTGRLLRANQISFNWDRLASWINLTEQWPYRTSWLILYLEETEGIPDQMTLKTIYERISKNIPTTKDVEPLLEIDGDIRNFEVFL
SSRTPVLVARDVKVFLPCTVNLDPKLREIIADVRAAREQISIGGLAYPPLPLHEGPPRAPSGYSQPPSVCSSTSFNGPFAGGVVSPQPHS
SYYSGMTGPQHPFYNRVGGSRSGLWILRTLPGVMTIPSLASGCXRRWGGLKERVXGLRSKEPQIILKFKXKITTWDSELPSIMKTTGLPI
RMILTSFWPNXTLAMGRKPQIPRTRRKRNLLALRKSPKSPKTVFTIXNSQKGDASPSTPEENETTTTSAFTIQEYFAKRMAALKNKPQVP

>In-frame_KIDINS220_ENST00000418530_chr2_8890242_-_PINX1_ENST00000519088_chr8_10692285_-_1264aa
MIAAEQGNLEIVKELIKNGANCNLEDLDNWTALISASKEGHVHIVEELLKCGVNLEHRDMGGWTALMWACYKGRTDVVELLLSHGANPSV
TGLYSVYPIIWAAGRGHADIVHLLLQNGAKVNCSDKYGTTPLVWAARKGHLECVKHLLAMGADVDQEGANSMTALIVAVKGGYTQSVKEI
LKRNPNVNLTDKDGNTALMIASKEGHTEIVQDLLDAGTYVNIPDRSGDTVLIGAVRGGHVEIVRALLQKYADIDIRGQDNKTALYWAVEK
GNATMVRDILQCNPDTEICTKDGETPLIKATKMRNIEVVELLLDKGAKVSAVDKKGDTPLHIAIRGRSRKLAELLLRNPKDGRLLYRPNK
AGETPYNIDCSHQKSILTQIFGARHLSPTETDGDMLGYDLYSSALADILSEPTMQPPICVGLYAQWGSGKSFLLKKLEDEMKTFAGQQIE
PLFQFSWLIVFLTLLLCGGLGLLFAFTVHPNLGIAVSLSFLALLYIFFIVIYFGGRREGESWNWAWVLSTRLARHIGYLELLLKLMFVNP
PELPEQTTKALPVRFLFTDYNRLSSVGGETSLAEMIATLSDACEREFGFLATRLFRVFKTEDTQGKKKWKKTCCLPSFVIFLFIIGCIIS
GITLLAIFRVDPKHLTVNAVLISIASVVGLAFVLNCRTWWQVLDSLLNSQRKRLHNAASKLHKLKSEGFMKVLKCEVELMARMAKTIDSF
TQNQTRLVVIIDGLDACEQDKVLQMLDTVRVLFSKGPFIAIFASDPHIIIKAINQNLNSVLRDSNINGHDYMRNIVHLPVFLNSRGLSNA
RKFLVTSATNGDVPCSDTTGIQEDADRRVSQNSLGEMTKLGSKTALNRRDTYRRRQMQRTITRQMSFDLTKLLVTEDWFSDISPQTMRRL
LNIVSVTGRLLRANQISFNWDRLASWINLTEQWPYRTSWLILYLEETEGIPDQMTLKTIYERISKNIPTTKDVEPLLEIDGDIRNFEVFL
SSRTPVLVARDVKVFLPCTVNLDPKLREIIADVRAAREQISIGGLAYPPLPLHEGPPRAPSGYSQPPSVCSSTSFNGPFAGGVVSPQPHS
SYYSGMTGPQHPFYNRVGGSRSGLWILRTLPGVMTIPSLASGCXRRWGGLKERVXGLRSKEPQIILKFKXKITTWDSELPSIMKTTGLPI
RMILTSFWPNXTLAMGRKPQIPRTRRKRNLLALRKSPKSPKTVFTIXNSQKGDASPSTPEENETTTTSAFTIQEYFAKRMAALKNKPQVP


* Fusion transcript sequences (only coding sequence (CDS) region).
>In-frame_KIDINS220_ENST00000418530_chr2_8890242_-_PINX1_ENST00000314787_chr8_10692285_-_4256nt
ATGATAGCTGCCGAACAAGGCAATCTGGAAATAGTGAAGGAATTAATTAAGAATGGAGCTAACTGCAATCTGGAAGATTTGGATAATTGG
ACAGCACTTATATCTGCATCGAAAGAAGGGCATGTGCACATCGTAGAGGAACTACTGAAATGTGGGGTTAACTTGGAGCACCGTGATATG
GGAGGATGGACAGCTCTTATGTGGGCATGTTACAAAGGCCGTACTGACGTAGTAGAGTTGCTTCTTTCTCATGGTGCCAATCCAAGTGTC
ACTGGTCTGTACAGTGTTTACCCAATCATTTGGGCAGCAGGGAGAGGCCATGCAGATATAGTTCATCTTTTACTGCAAAATGGTGCTAAA
GTCAACTGCTCTGATAAGTATGGAACCACCCCTTTAGTTTGGGCTGCACGAAAGGGTCATTTGGAATGTGTGAAACATTTATTGGCCATG
GGAGCTGATGTGGATCAAGAAGGAGCTAATTCAATGACTGCACTTATTGTGGCAGTGAAAGGAGGTTACACACAGTCAGTAAAAGAAATT
TTGAAGAGGAATCCAAATGTAAACTTAACAGATAAAGATGGAAATACAGCTTTGATGATTGCATCAAAGGAGGGACATACGGAGATTGTG
CAGGATCTGCTCGACGCTGGAACATATGTGAACATACCTGACAGGAGTGGGGATACTGTGTTGATTGGCGCTGTCAGAGGTGGTCATGTT
GAAATTGTTCGAGCGCTTCTCCAAAAATATGCTGATATAGACATTAGAGGACAGGATAATAAAACTGCTTTGTATTGGGCTGTTGAGAAA
GGAAATGCAACAATGGTGAGAGATATCTTACAGTGCAATCCTGACACTGAAATATGCACAAAGGATGGTGAAACGCCACTTATAAAGGCT
ACCAAGATGAGAAACATTGAAGTGGTGGAGCTGCTGCTAGATAAAGGTGCTAAAGTGTCTGCTGTAGATAAGAAAGGAGATACTCCCTTG
CATATTGCTATTCGTGGAAGGAGCCGGAAACTGGCAGAACTGCTTTTAAGAAATCCCAAAGATGGGCGATTACTTTATAGGCCCAACAAA
GCAGGCGAGACTCCTTATAATATTGACTGTAGCCATCAGAAGAGTATTTTAACTCAAATATTTGGAGCCAGACACTTGTCTCCTACTGAA
ACAGACGGTGACATGCTTGGATATGATTTATATAGCAGTGCCCTGGCAGATATTCTCAGTGAGCCTACCATGCAGCCACCCATTTGTGTG
GGGTTATATGCACAGTGGGGAAGTGGGAAATCTTTCTTACTCAAGAAACTAGAAGACGAAATGAAAACCTTCGCCGGACAACAGATTGAG
CCTCTCTTTCAGTTCTCATGGCTCATAGTGTTTCTTACCCTGCTACTTTGTGGAGGGCTTGGTTTATTGTTTGCCTTCACGGTCCACCCA
AATCTTGGAATAGCAGTGTCACTGAGCTTCTTGGCTCTCTTATATATATTCTTTATTGTCATTTACTTTGGTGGACGAAGAGAAGGAGAG
AGTTGGAATTGGGCCTGGGTCCTCAGCACTAGATTGGCAAGACATATTGGATATTTGGAACTCCTCCTTAAATTGATGTTTGTGAATCCA
CCTGAGTTGCCAGAGCAGACTACTAAAGCTTTACCTGTGAGGTTTTTGTTTACAGATTACAATAGACTGTCCAGTGTAGGTGGAGAAACT
TCTCTGGCTGAAATGATTGCAACCCTCTCGGATGCTTGTGAAAGAGAGTTTGGCTTTTTGGCAACCAGGCTTTTTCGAGTATTCAAGACT
GAAGATACTCAGGGTAAAAAGAAATGGAAAAAAACATGTTGTCTCCCATCTTTTGTCATCTTCCTTTTTATCATTGGCTGCATTATATCT
GGAATTACTCTTCTGGCTATATTTAGAGTTGACCCAAAGCATCTGACTGTAAATGCTGTCCTCATATCAATCGCATCTGTAGTGGGATTG
GCCTTTGTGTTGAACTGTCGTACATGGTGGCAAGTGCTGGACTCGCTCCTGAATTCCCAAAGAAAACGCCTCCATAATGCAGCCTCCAAA
CTGCACAAATTGAAAAGTGAAGGATTCATGAAAGTTCTTAAATGTGAAGTGGAATTGATGGCCAGGATGGCAAAAACCATTGACAGCTTC
ACTCAGAATCAGACAAGGCTGGTGGTCATCATCGATGGATTAGATGCCTGTGAGCAGGACAAAGTCCTTCAGATGCTGGACACTGTCCGA
GTTCTGTTTTCAAAAGGCCCGTTCATTGCCATTTTTGCAAGTGATCCACATATTATCATAAAGGCAATTAACCAGAACCTCAATAGTGTG
CTTCGGGATTCAAATATAAATGGCCATGACTACATGCGCAACATAGTCCACTTGCCTGTGTTCCTTAATAGTCGTGGACTAAGCAATGCA
AGAAAATTTCTCGTAACTTCAGCAACAAATGGAGACGTTCCATGCTCAGATACTACAGGGATACAGGAAGATGCTGACAGAAGAGTTTCA
CAGAACAGCCTTGGGGAGATGACAAAACTTGGTAGCAAGACAGCCCTCAATAGACGGGACACTTACCGAAGAAGGCAGATGCAGAGGACC
ATCACTCGCCAGATGTCCTTTGATCTTACAAAACTGCTGGTTACCGAGGACTGGTTCAGTGACATCAGTCCCCAGACCATGAGAAGATTA
CTTAATATTGTTTCTGTGACAGGACGATTACTGAGAGCCAATCAGATTAGTTTCAACTGGGACAGGCTTGCTAGCTGGATCAACCTTACT
GAGCAGTGGCCATACCGGACTTCATGGCTCATATTATATTTGGAAGAGACTGAAGGTATTCCAGATCAAATGACATTAAAAACCATCTAC
GAAAGAATATCAAAGAATATTCCAACAACTAAGGATGTTGAGCCACTTCTTGAAATTGATGGAGATATAAGAAATTTTGAAGTGTTTTTG
TCTTCAAGGACCCCAGTTCTTGTGGCTCGAGATGTAAAAGTCTTTTTGCCATGCACTGTAAACCTAGATCCCAAACTACGGGAAATTATT
GCAGATGTTCGTGCTGCCAGAGAGCAGATCAGTATTGGAGGACTGGCGTACCCCCCGCTCCCTCTACATGAGGGTCCTCCTAGGGCGCCA
TCAGGGTACAGCCAGCCCCCATCCGTGTGCTCTTCCACGTCCTTCAATGGGCCCTTCGCAGGTGGAGTGGTGTCACCACAGCCTCACAGC
AGCTATTACAGCGGCATGACGGGCCCTCAGCATCCCTTCTACAACAGGGTCGGCGGAAGCAGAAGTGGGCTGTGGATCCTCAGAACACTG
CCTGGAGTAATGACGATTCCAAGTTTGGCCAGCGGATGCTAGAGAAGATGGGGTGGTCTAAAGGAAAGGGTTTAGGGGCTCAGGAGCAAG
GAGCCACAGATCATATTAAAGTTCAAGTGAAAAATAACCACCTGGGACTCGGAGCTACCATCAATAATGAAGACAACTGGATTGCCCATC
AGGATGATTTTAACCAGCTTCTGGCCGAACTGAACACTTGCCATGGGCAGGAAACCACAGATTCCTCGGACAAGAAGGAAAAGAAATCTT
TTAGCCTTGAGGAAAAGTCCAAAATCTCCAAAAACCGTGTTCACTATATGAAATTCACAAAAGGGAAGGATCTGTCATCTCGGAGCAAAA
CAGATCTTGACTGCATTTTTGGGAAAAGACAGAGTAAGAAGACTCCCGAGGGCGATGCCAGTCCCTCCACTCCAGAGGAGAACGAAACCA
CGACAACCAGCGCCTTCACCATCCAGGAGTACTTTGCCAAGCGGATGGCAGCACTGAAGAACAAGCCCCAGGTTCCAGTTCCAGGGTCTG
ACATTTCTGAGACGCAGGTGGAACGTAAAAGGGGGAAGAAAAGAAATAAAGAGGCCACAGGTAAAGATGTGGAAAGTTACCTCCAGCCTA
AGGCCAAGAGGCACACGGAGGGAAAGCCCGAGAGGGCCGAGGCCCAGGAGCGAGTGGCCAAGAAGAAGAGCGCGCCAGCAGAAGAGCAGC
TCAGAGGCCCCTGCTGGGACCAGAGTTCCAAGGCCTCTGCTCAGGATGCAGGGGACCATGTGCAGCCGCCTGAGGGCCGGGACTTCACCC
TGAAGCCCAAAAAGAGGAGAGGGAAGAAAAAGCTGCAAAAACCAGTAGAGATAGCAGAGGACGCTACACTAGAAGAAACGCTAGTGAAAA

>In-frame_KIDINS220_ENST00000418530_chr2_8890242_-_PINX1_ENST00000426190_chr8_10692285_-_3794nt
ATGATAGCTGCCGAACAAGGCAATCTGGAAATAGTGAAGGAATTAATTAAGAATGGAGCTAACTGCAATCTGGAAGATTTGGATAATTGG
ACAGCACTTATATCTGCATCGAAAGAAGGGCATGTGCACATCGTAGAGGAACTACTGAAATGTGGGGTTAACTTGGAGCACCGTGATATG
GGAGGATGGACAGCTCTTATGTGGGCATGTTACAAAGGCCGTACTGACGTAGTAGAGTTGCTTCTTTCTCATGGTGCCAATCCAAGTGTC
ACTGGTCTGTACAGTGTTTACCCAATCATTTGGGCAGCAGGGAGAGGCCATGCAGATATAGTTCATCTTTTACTGCAAAATGGTGCTAAA
GTCAACTGCTCTGATAAGTATGGAACCACCCCTTTAGTTTGGGCTGCACGAAAGGGTCATTTGGAATGTGTGAAACATTTATTGGCCATG
GGAGCTGATGTGGATCAAGAAGGAGCTAATTCAATGACTGCACTTATTGTGGCAGTGAAAGGAGGTTACACACAGTCAGTAAAAGAAATT
TTGAAGAGGAATCCAAATGTAAACTTAACAGATAAAGATGGAAATACAGCTTTGATGATTGCATCAAAGGAGGGACATACGGAGATTGTG
CAGGATCTGCTCGACGCTGGAACATATGTGAACATACCTGACAGGAGTGGGGATACTGTGTTGATTGGCGCTGTCAGAGGTGGTCATGTT
GAAATTGTTCGAGCGCTTCTCCAAAAATATGCTGATATAGACATTAGAGGACAGGATAATAAAACTGCTTTGTATTGGGCTGTTGAGAAA
GGAAATGCAACAATGGTGAGAGATATCTTACAGTGCAATCCTGACACTGAAATATGCACAAAGGATGGTGAAACGCCACTTATAAAGGCT
ACCAAGATGAGAAACATTGAAGTGGTGGAGCTGCTGCTAGATAAAGGTGCTAAAGTGTCTGCTGTAGATAAGAAAGGAGATACTCCCTTG
CATATTGCTATTCGTGGAAGGAGCCGGAAACTGGCAGAACTGCTTTTAAGAAATCCCAAAGATGGGCGATTACTTTATAGGCCCAACAAA
GCAGGCGAGACTCCTTATAATATTGACTGTAGCCATCAGAAGAGTATTTTAACTCAAATATTTGGAGCCAGACACTTGTCTCCTACTGAA
ACAGACGGTGACATGCTTGGATATGATTTATATAGCAGTGCCCTGGCAGATATTCTCAGTGAGCCTACCATGCAGCCACCCATTTGTGTG
GGGTTATATGCACAGTGGGGAAGTGGGAAATCTTTCTTACTCAAGAAACTAGAAGACGAAATGAAAACCTTCGCCGGACAACAGATTGAG
CCTCTCTTTCAGTTCTCATGGCTCATAGTGTTTCTTACCCTGCTACTTTGTGGAGGGCTTGGTTTATTGTTTGCCTTCACGGTCCACCCA
AATCTTGGAATAGCAGTGTCACTGAGCTTCTTGGCTCTCTTATATATATTCTTTATTGTCATTTACTTTGGTGGACGAAGAGAAGGAGAG
AGTTGGAATTGGGCCTGGGTCCTCAGCACTAGATTGGCAAGACATATTGGATATTTGGAACTCCTCCTTAAATTGATGTTTGTGAATCCA
CCTGAGTTGCCAGAGCAGACTACTAAAGCTTTACCTGTGAGGTTTTTGTTTACAGATTACAATAGACTGTCCAGTGTAGGTGGAGAAACT
TCTCTGGCTGAAATGATTGCAACCCTCTCGGATGCTTGTGAAAGAGAGTTTGGCTTTTTGGCAACCAGGCTTTTTCGAGTATTCAAGACT
GAAGATACTCAGGGTAAAAAGAAATGGAAAAAAACATGTTGTCTCCCATCTTTTGTCATCTTCCTTTTTATCATTGGCTGCATTATATCT
GGAATTACTCTTCTGGCTATATTTAGAGTTGACCCAAAGCATCTGACTGTAAATGCTGTCCTCATATCAATCGCATCTGTAGTGGGATTG
GCCTTTGTGTTGAACTGTCGTACATGGTGGCAAGTGCTGGACTCGCTCCTGAATTCCCAAAGAAAACGCCTCCATAATGCAGCCTCCAAA
CTGCACAAATTGAAAAGTGAAGGATTCATGAAAGTTCTTAAATGTGAAGTGGAATTGATGGCCAGGATGGCAAAAACCATTGACAGCTTC
ACTCAGAATCAGACAAGGCTGGTGGTCATCATCGATGGATTAGATGCCTGTGAGCAGGACAAAGTCCTTCAGATGCTGGACACTGTCCGA
GTTCTGTTTTCAAAAGGCCCGTTCATTGCCATTTTTGCAAGTGATCCACATATTATCATAAAGGCAATTAACCAGAACCTCAATAGTGTG
CTTCGGGATTCAAATATAAATGGCCATGACTACATGCGCAACATAGTCCACTTGCCTGTGTTCCTTAATAGTCGTGGACTAAGCAATGCA
AGAAAATTTCTCGTAACTTCAGCAACAAATGGAGACGTTCCATGCTCAGATACTACAGGGATACAGGAAGATGCTGACAGAAGAGTTTCA
CAGAACAGCCTTGGGGAGATGACAAAACTTGGTAGCAAGACAGCCCTCAATAGACGGGACACTTACCGAAGAAGGCAGATGCAGAGGACC
ATCACTCGCCAGATGTCCTTTGATCTTACAAAACTGCTGGTTACCGAGGACTGGTTCAGTGACATCAGTCCCCAGACCATGAGAAGATTA
CTTAATATTGTTTCTGTGACAGGACGATTACTGAGAGCCAATCAGATTAGTTTCAACTGGGACAGGCTTGCTAGCTGGATCAACCTTACT
GAGCAGTGGCCATACCGGACTTCATGGCTCATATTATATTTGGAAGAGACTGAAGGTATTCCAGATCAAATGACATTAAAAACCATCTAC
GAAAGAATATCAAAGAATATTCCAACAACTAAGGATGTTGAGCCACTTCTTGAAATTGATGGAGATATAAGAAATTTTGAAGTGTTTTTG
TCTTCAAGGACCCCAGTTCTTGTGGCTCGAGATGTAAAAGTCTTTTTGCCATGCACTGTAAACCTAGATCCCAAACTACGGGAAATTATT
GCAGATGTTCGTGCTGCCAGAGAGCAGATCAGTATTGGAGGACTGGCGTACCCCCCGCTCCCTCTACATGAGGGTCCTCCTAGGGCGCCA
TCAGGGTACAGCCAGCCCCCATCCGTGTGCTCTTCCACGTCCTTCAATGGGCCCTTCGCAGGTGGAGTGGTGTCACCACAGCCTCACAGC
AGCTATTACAGCGGCATGACGGGCCCTCAGCATCCCTTCTACAACAGGGTCGGCGGAAGCAGAAGTGGGCTGTGGATCCTCAGAACACTG
CCTGGAGTAATGACGATTCCAAGTTTGGCCAGCGGATGCTAGAGAAGATGGGGTGGTCTAAAGGAAAGGGTTTAGGGGCTCAGGAGCAAG
GAGCCACAGATCATATTAAAGTTCAAGTGAAAAATAACCACCTGGGACTCGGAGCTACCATCAATAATGAAGACAACTGGATTGCCCATC
AGGATGATTTTAACCAGCTTCTGGCCGAACTGAACACTTGCCATGGGCAGGAAACCACAGATTCCTCGGACAAGAAGGAAAAGAAATCTT
TTAGCCTTGAGGAAAAGTCCAAAATCTCCAAAAACCGTGTTCACTATATGAAATTCACAAAAGGGCGATGCCAGTCCCTCCACTCCAGAG
GAGAACGAAACCACGACAACCAGCGCCTTCACCATCCAGGAGTACTTTGCCAAGCGGATGGCAGCACTGAAGAACAAGCCCCAGGTTCCA

>In-frame_KIDINS220_ENST00000418530_chr2_8890242_-_PINX1_ENST00000519088_chr8_10692285_-_3794nt
ATGATAGCTGCCGAACAAGGCAATCTGGAAATAGTGAAGGAATTAATTAAGAATGGAGCTAACTGCAATCTGGAAGATTTGGATAATTGG
ACAGCACTTATATCTGCATCGAAAGAAGGGCATGTGCACATCGTAGAGGAACTACTGAAATGTGGGGTTAACTTGGAGCACCGTGATATG
GGAGGATGGACAGCTCTTATGTGGGCATGTTACAAAGGCCGTACTGACGTAGTAGAGTTGCTTCTTTCTCATGGTGCCAATCCAAGTGTC
ACTGGTCTGTACAGTGTTTACCCAATCATTTGGGCAGCAGGGAGAGGCCATGCAGATATAGTTCATCTTTTACTGCAAAATGGTGCTAAA
GTCAACTGCTCTGATAAGTATGGAACCACCCCTTTAGTTTGGGCTGCACGAAAGGGTCATTTGGAATGTGTGAAACATTTATTGGCCATG
GGAGCTGATGTGGATCAAGAAGGAGCTAATTCAATGACTGCACTTATTGTGGCAGTGAAAGGAGGTTACACACAGTCAGTAAAAGAAATT
TTGAAGAGGAATCCAAATGTAAACTTAACAGATAAAGATGGAAATACAGCTTTGATGATTGCATCAAAGGAGGGACATACGGAGATTGTG
CAGGATCTGCTCGACGCTGGAACATATGTGAACATACCTGACAGGAGTGGGGATACTGTGTTGATTGGCGCTGTCAGAGGTGGTCATGTT
GAAATTGTTCGAGCGCTTCTCCAAAAATATGCTGATATAGACATTAGAGGACAGGATAATAAAACTGCTTTGTATTGGGCTGTTGAGAAA
GGAAATGCAACAATGGTGAGAGATATCTTACAGTGCAATCCTGACACTGAAATATGCACAAAGGATGGTGAAACGCCACTTATAAAGGCT
ACCAAGATGAGAAACATTGAAGTGGTGGAGCTGCTGCTAGATAAAGGTGCTAAAGTGTCTGCTGTAGATAAGAAAGGAGATACTCCCTTG
CATATTGCTATTCGTGGAAGGAGCCGGAAACTGGCAGAACTGCTTTTAAGAAATCCCAAAGATGGGCGATTACTTTATAGGCCCAACAAA
GCAGGCGAGACTCCTTATAATATTGACTGTAGCCATCAGAAGAGTATTTTAACTCAAATATTTGGAGCCAGACACTTGTCTCCTACTGAA
ACAGACGGTGACATGCTTGGATATGATTTATATAGCAGTGCCCTGGCAGATATTCTCAGTGAGCCTACCATGCAGCCACCCATTTGTGTG
GGGTTATATGCACAGTGGGGAAGTGGGAAATCTTTCTTACTCAAGAAACTAGAAGACGAAATGAAAACCTTCGCCGGACAACAGATTGAG
CCTCTCTTTCAGTTCTCATGGCTCATAGTGTTTCTTACCCTGCTACTTTGTGGAGGGCTTGGTTTATTGTTTGCCTTCACGGTCCACCCA
AATCTTGGAATAGCAGTGTCACTGAGCTTCTTGGCTCTCTTATATATATTCTTTATTGTCATTTACTTTGGTGGACGAAGAGAAGGAGAG
AGTTGGAATTGGGCCTGGGTCCTCAGCACTAGATTGGCAAGACATATTGGATATTTGGAACTCCTCCTTAAATTGATGTTTGTGAATCCA
CCTGAGTTGCCAGAGCAGACTACTAAAGCTTTACCTGTGAGGTTTTTGTTTACAGATTACAATAGACTGTCCAGTGTAGGTGGAGAAACT
TCTCTGGCTGAAATGATTGCAACCCTCTCGGATGCTTGTGAAAGAGAGTTTGGCTTTTTGGCAACCAGGCTTTTTCGAGTATTCAAGACT
GAAGATACTCAGGGTAAAAAGAAATGGAAAAAAACATGTTGTCTCCCATCTTTTGTCATCTTCCTTTTTATCATTGGCTGCATTATATCT
GGAATTACTCTTCTGGCTATATTTAGAGTTGACCCAAAGCATCTGACTGTAAATGCTGTCCTCATATCAATCGCATCTGTAGTGGGATTG
GCCTTTGTGTTGAACTGTCGTACATGGTGGCAAGTGCTGGACTCGCTCCTGAATTCCCAAAGAAAACGCCTCCATAATGCAGCCTCCAAA
CTGCACAAATTGAAAAGTGAAGGATTCATGAAAGTTCTTAAATGTGAAGTGGAATTGATGGCCAGGATGGCAAAAACCATTGACAGCTTC
ACTCAGAATCAGACAAGGCTGGTGGTCATCATCGATGGATTAGATGCCTGTGAGCAGGACAAAGTCCTTCAGATGCTGGACACTGTCCGA
GTTCTGTTTTCAAAAGGCCCGTTCATTGCCATTTTTGCAAGTGATCCACATATTATCATAAAGGCAATTAACCAGAACCTCAATAGTGTG
CTTCGGGATTCAAATATAAATGGCCATGACTACATGCGCAACATAGTCCACTTGCCTGTGTTCCTTAATAGTCGTGGACTAAGCAATGCA
AGAAAATTTCTCGTAACTTCAGCAACAAATGGAGACGTTCCATGCTCAGATACTACAGGGATACAGGAAGATGCTGACAGAAGAGTTTCA
CAGAACAGCCTTGGGGAGATGACAAAACTTGGTAGCAAGACAGCCCTCAATAGACGGGACACTTACCGAAGAAGGCAGATGCAGAGGACC
ATCACTCGCCAGATGTCCTTTGATCTTACAAAACTGCTGGTTACCGAGGACTGGTTCAGTGACATCAGTCCCCAGACCATGAGAAGATTA
CTTAATATTGTTTCTGTGACAGGACGATTACTGAGAGCCAATCAGATTAGTTTCAACTGGGACAGGCTTGCTAGCTGGATCAACCTTACT
GAGCAGTGGCCATACCGGACTTCATGGCTCATATTATATTTGGAAGAGACTGAAGGTATTCCAGATCAAATGACATTAAAAACCATCTAC
GAAAGAATATCAAAGAATATTCCAACAACTAAGGATGTTGAGCCACTTCTTGAAATTGATGGAGATATAAGAAATTTTGAAGTGTTTTTG
TCTTCAAGGACCCCAGTTCTTGTGGCTCGAGATGTAAAAGTCTTTTTGCCATGCACTGTAAACCTAGATCCCAAACTACGGGAAATTATT
GCAGATGTTCGTGCTGCCAGAGAGCAGATCAGTATTGGAGGACTGGCGTACCCCCCGCTCCCTCTACATGAGGGTCCTCCTAGGGCGCCA
TCAGGGTACAGCCAGCCCCCATCCGTGTGCTCTTCCACGTCCTTCAATGGGCCCTTCGCAGGTGGAGTGGTGTCACCACAGCCTCACAGC
AGCTATTACAGCGGCATGACGGGCCCTCAGCATCCCTTCTACAACAGGGTCGGCGGAAGCAGAAGTGGGCTGTGGATCCTCAGAACACTG
CCTGGAGTAATGACGATTCCAAGTTTGGCCAGCGGATGCTAGAGAAGATGGGGTGGTCTAAAGGAAAGGGTTTAGGGGCTCAGGAGCAAG
GAGCCACAGATCATATTAAAGTTCAAGTGAAAAATAACCACCTGGGACTCGGAGCTACCATCAATAATGAAGACAACTGGATTGCCCATC
AGGATGATTTTAACCAGCTTCTGGCCGAACTGAACACTTGCCATGGGCAGGAAACCACAGATTCCTCGGACAAGAAGGAAAAGAAATCTT
TTAGCCTTGAGGAAAAGTCCAAAATCTCCAAAAACCGTGTTCACTATATGAAATTCACAAAAGGGCGATGCCAGTCCCTCCACTCCAGAG
GAGAACGAAACCACGACAACCAGCGCCTTCACCATCCAGGAGTACTTTGCCAAGCGGATGGCAGCACTGAAGAACAAGCCCCAGGTTCCA


* Fusion transcript sequences (Full-length transcript).
>In-frame_KIDINS220_ENST00000418530_chr2_8890242_-_PINX1_ENST00000314787_chr8_10692285_-_5002nt
ACGTGATCTGTCAGTTCGCGGAGAGGGAAGAATATGGCCGCCGGGTGTGGTGAGGGCGACGCGCTTGCAGTCGCCGTCTCTTGCTTCCCC
GTCCTCTGACATCGCCTGCAGCCGAGCGGGCCCGTTCCGCCGGAGCTGAGGACCAGGTATTCAAATAAAGTTAATTGCAGCTTTCTGTGA
AAATGTCAGTTTTGATATCACAGAGCGTCATAAATTATGTAGAGGAAGAAAACATTCCTGCTCTGAAAGCTCTTCTTGAAAAATGCAAAG
ATGTAGATGAGAGAAATGAGTGTGGCCAGACTCCACTGATGATAGCTGCCGAACAAGGCAATCTGGAAATAGTGAAGGAATTAATTAAGA
ATGGAGCTAACTGCAATCTGGAAGATTTGGATAATTGGACAGCACTTATATCTGCATCGAAAGAAGGGCATGTGCACATCGTAGAGGAAC
TACTGAAATGTGGGGTTAACTTGGAGCACCGTGATATGGGAGGATGGACAGCTCTTATGTGGGCATGTTACAAAGGCCGTACTGACGTAG
TAGAGTTGCTTCTTTCTCATGGTGCCAATCCAAGTGTCACTGGTCTGTACAGTGTTTACCCAATCATTTGGGCAGCAGGGAGAGGCCATG
CAGATATAGTTCATCTTTTACTGCAAAATGGTGCTAAAGTCAACTGCTCTGATAAGTATGGAACCACCCCTTTAGTTTGGGCTGCACGAA
AGGGTCATTTGGAATGTGTGAAACATTTATTGGCCATGGGAGCTGATGTGGATCAAGAAGGAGCTAATTCAATGACTGCACTTATTGTGG
CAGTGAAAGGAGGTTACACACAGTCAGTAAAAGAAATTTTGAAGAGGAATCCAAATGTAAACTTAACAGATAAAGATGGAAATACAGCTT
TGATGATTGCATCAAAGGAGGGACATACGGAGATTGTGCAGGATCTGCTCGACGCTGGAACATATGTGAACATACCTGACAGGAGTGGGG
ATACTGTGTTGATTGGCGCTGTCAGAGGTGGTCATGTTGAAATTGTTCGAGCGCTTCTCCAAAAATATGCTGATATAGACATTAGAGGAC
AGGATAATAAAACTGCTTTGTATTGGGCTGTTGAGAAAGGAAATGCAACAATGGTGAGAGATATCTTACAGTGCAATCCTGACACTGAAA
TATGCACAAAGGATGGTGAAACGCCACTTATAAAGGCTACCAAGATGAGAAACATTGAAGTGGTGGAGCTGCTGCTAGATAAAGGTGCTA
AAGTGTCTGCTGTAGATAAGAAAGGAGATACTCCCTTGCATATTGCTATTCGTGGAAGGAGCCGGAAACTGGCAGAACTGCTTTTAAGAA
ATCCCAAAGATGGGCGATTACTTTATAGGCCCAACAAAGCAGGCGAGACTCCTTATAATATTGACTGTAGCCATCAGAAGAGTATTTTAA
CTCAAATATTTGGAGCCAGACACTTGTCTCCTACTGAAACAGACGGTGACATGCTTGGATATGATTTATATAGCAGTGCCCTGGCAGATA
TTCTCAGTGAGCCTACCATGCAGCCACCCATTTGTGTGGGGTTATATGCACAGTGGGGAAGTGGGAAATCTTTCTTACTCAAGAAACTAG
AAGACGAAATGAAAACCTTCGCCGGACAACAGATTGAGCCTCTCTTTCAGTTCTCATGGCTCATAGTGTTTCTTACCCTGCTACTTTGTG
GAGGGCTTGGTTTATTGTTTGCCTTCACGGTCCACCCAAATCTTGGAATAGCAGTGTCACTGAGCTTCTTGGCTCTCTTATATATATTCT
TTATTGTCATTTACTTTGGTGGACGAAGAGAAGGAGAGAGTTGGAATTGGGCCTGGGTCCTCAGCACTAGATTGGCAAGACATATTGGAT
ATTTGGAACTCCTCCTTAAATTGATGTTTGTGAATCCACCTGAGTTGCCAGAGCAGACTACTAAAGCTTTACCTGTGAGGTTTTTGTTTA
CAGATTACAATAGACTGTCCAGTGTAGGTGGAGAAACTTCTCTGGCTGAAATGATTGCAACCCTCTCGGATGCTTGTGAAAGAGAGTTTG
GCTTTTTGGCAACCAGGCTTTTTCGAGTATTCAAGACTGAAGATACTCAGGGTAAAAAGAAATGGAAAAAAACATGTTGTCTCCCATCTT
TTGTCATCTTCCTTTTTATCATTGGCTGCATTATATCTGGAATTACTCTTCTGGCTATATTTAGAGTTGACCCAAAGCATCTGACTGTAA
ATGCTGTCCTCATATCAATCGCATCTGTAGTGGGATTGGCCTTTGTGTTGAACTGTCGTACATGGTGGCAAGTGCTGGACTCGCTCCTGA
ATTCCCAAAGAAAACGCCTCCATAATGCAGCCTCCAAACTGCACAAATTGAAAAGTGAAGGATTCATGAAAGTTCTTAAATGTGAAGTGG
AATTGATGGCCAGGATGGCAAAAACCATTGACAGCTTCACTCAGAATCAGACAAGGCTGGTGGTCATCATCGATGGATTAGATGCCTGTG
AGCAGGACAAAGTCCTTCAGATGCTGGACACTGTCCGAGTTCTGTTTTCAAAAGGCCCGTTCATTGCCATTTTTGCAAGTGATCCACATA
TTATCATAAAGGCAATTAACCAGAACCTCAATAGTGTGCTTCGGGATTCAAATATAAATGGCCATGACTACATGCGCAACATAGTCCACT
TGCCTGTGTTCCTTAATAGTCGTGGACTAAGCAATGCAAGAAAATTTCTCGTAACTTCAGCAACAAATGGAGACGTTCCATGCTCAGATA
CTACAGGGATACAGGAAGATGCTGACAGAAGAGTTTCACAGAACAGCCTTGGGGAGATGACAAAACTTGGTAGCAAGACAGCCCTCAATA
GACGGGACACTTACCGAAGAAGGCAGATGCAGAGGACCATCACTCGCCAGATGTCCTTTGATCTTACAAAACTGCTGGTTACCGAGGACT
GGTTCAGTGACATCAGTCCCCAGACCATGAGAAGATTACTTAATATTGTTTCTGTGACAGGACGATTACTGAGAGCCAATCAGATTAGTT
TCAACTGGGACAGGCTTGCTAGCTGGATCAACCTTACTGAGCAGTGGCCATACCGGACTTCATGGCTCATATTATATTTGGAAGAGACTG
AAGGTATTCCAGATCAAATGACATTAAAAACCATCTACGAAAGAATATCAAAGAATATTCCAACAACTAAGGATGTTGAGCCACTTCTTG
AAATTGATGGAGATATAAGAAATTTTGAAGTGTTTTTGTCTTCAAGGACCCCAGTTCTTGTGGCTCGAGATGTAAAAGTCTTTTTGCCAT
GCACTGTAAACCTAGATCCCAAACTACGGGAAATTATTGCAGATGTTCGTGCTGCCAGAGAGCAGATCAGTATTGGAGGACTGGCGTACC
CCCCGCTCCCTCTACATGAGGGTCCTCCTAGGGCGCCATCAGGGTACAGCCAGCCCCCATCCGTGTGCTCTTCCACGTCCTTCAATGGGC
CCTTCGCAGGTGGAGTGGTGTCACCACAGCCTCACAGCAGCTATTACAGCGGCATGACGGGCCCTCAGCATCCCTTCTACAACAGGGTCG
GCGGAAGCAGAAGTGGGCTGTGGATCCTCAGAACACTGCCTGGAGTAATGACGATTCCAAGTTTGGCCAGCGGATGCTAGAGAAGATGGG
GTGGTCTAAAGGAAAGGGTTTAGGGGCTCAGGAGCAAGGAGCCACAGATCATATTAAAGTTCAAGTGAAAAATAACCACCTGGGACTCGG
AGCTACCATCAATAATGAAGACAACTGGATTGCCCATCAGGATGATTTTAACCAGCTTCTGGCCGAACTGAACACTTGCCATGGGCAGGA
AACCACAGATTCCTCGGACAAGAAGGAAAAGAAATCTTTTAGCCTTGAGGAAAAGTCCAAAATCTCCAAAAACCGTGTTCACTATATGAA
ATTCACAAAAGGGAAGGATCTGTCATCTCGGAGCAAAACAGATCTTGACTGCATTTTTGGGAAAAGACAGAGTAAGAAGACTCCCGAGGG
CGATGCCAGTCCCTCCACTCCAGAGGAGAACGAAACCACGACAACCAGCGCCTTCACCATCCAGGAGTACTTTGCCAAGCGGATGGCAGC
ACTGAAGAACAAGCCCCAGGTTCCAGTTCCAGGGTCTGACATTTCTGAGACGCAGGTGGAACGTAAAAGGGGGAAGAAAAGAAATAAAGA
GGCCACAGGTAAAGATGTGGAAAGTTACCTCCAGCCTAAGGCCAAGAGGCACACGGAGGGAAAGCCCGAGAGGGCCGAGGCCCAGGAGCG
AGTGGCCAAGAAGAAGAGCGCGCCAGCAGAAGAGCAGCTCAGAGGCCCCTGCTGGGACCAGAGTTCCAAGGCCTCTGCTCAGGATGCAGG
GGACCATGTGCAGCCGCCTGAGGGCCGGGACTTCACCCTGAAGCCCAAAAAGAGGAGAGGGAAGAAAAAGCTGCAAAAACCAGTAGAGAT
AGCAGAGGACGCTACACTAGAAGAAACGCTAGTGAAAAAGAAGAAGAAGAAAGATTCCAAATGAATCCTTCCCAGCCGGGGCCTTCCGAC
CACTCAGCTGTCAGGGCACTGCGGGGGCAGACACCTCTGGCCTGAAGTCACAGCAGAGTTCACCCCAGAGCGCCTGGGCGCATCTTGTGG
CATGCCCATGGGCTGCCGAGTCCTGCCCTCTCGCCACATTTCCCCCAAGTTACATTCCCAGGAGGACCTTTTTAATGTTCTCAATCGTGG
CTCTCAGACACAAATAAATTTTTTTGTAAACTCTGAGCCCTTCAGCAAGAGAGTTTAATTATAATCATTACAAATACATGCATTCATGTA
AGTGTGCACACGTGTGTGTGCATGTGCGCATCTGTGTGTGTGTGTGTGTGTCACTATCTCCGTTTGCTCTCGGTTCCCTTCAATAACAAT

>In-frame_KIDINS220_ENST00000418530_chr2_8890242_-_PINX1_ENST00000426190_chr8_10692285_-_4923nt
ACGTGATCTGTCAGTTCGCGGAGAGGGAAGAATATGGCCGCCGGGTGTGGTGAGGGCGACGCGCTTGCAGTCGCCGTCTCTTGCTTCCCC
GTCCTCTGACATCGCCTGCAGCCGAGCGGGCCCGTTCCGCCGGAGCTGAGGACCAGGTATTCAAATAAAGTTAATTGCAGCTTTCTGTGA
AAATGTCAGTTTTGATATCACAGAGCGTCATAAATTATGTAGAGGAAGAAAACATTCCTGCTCTGAAAGCTCTTCTTGAAAAATGCAAAG
ATGTAGATGAGAGAAATGAGTGTGGCCAGACTCCACTGATGATAGCTGCCGAACAAGGCAATCTGGAAATAGTGAAGGAATTAATTAAGA
ATGGAGCTAACTGCAATCTGGAAGATTTGGATAATTGGACAGCACTTATATCTGCATCGAAAGAAGGGCATGTGCACATCGTAGAGGAAC
TACTGAAATGTGGGGTTAACTTGGAGCACCGTGATATGGGAGGATGGACAGCTCTTATGTGGGCATGTTACAAAGGCCGTACTGACGTAG
TAGAGTTGCTTCTTTCTCATGGTGCCAATCCAAGTGTCACTGGTCTGTACAGTGTTTACCCAATCATTTGGGCAGCAGGGAGAGGCCATG
CAGATATAGTTCATCTTTTACTGCAAAATGGTGCTAAAGTCAACTGCTCTGATAAGTATGGAACCACCCCTTTAGTTTGGGCTGCACGAA
AGGGTCATTTGGAATGTGTGAAACATTTATTGGCCATGGGAGCTGATGTGGATCAAGAAGGAGCTAATTCAATGACTGCACTTATTGTGG
CAGTGAAAGGAGGTTACACACAGTCAGTAAAAGAAATTTTGAAGAGGAATCCAAATGTAAACTTAACAGATAAAGATGGAAATACAGCTT
TGATGATTGCATCAAAGGAGGGACATACGGAGATTGTGCAGGATCTGCTCGACGCTGGAACATATGTGAACATACCTGACAGGAGTGGGG
ATACTGTGTTGATTGGCGCTGTCAGAGGTGGTCATGTTGAAATTGTTCGAGCGCTTCTCCAAAAATATGCTGATATAGACATTAGAGGAC
AGGATAATAAAACTGCTTTGTATTGGGCTGTTGAGAAAGGAAATGCAACAATGGTGAGAGATATCTTACAGTGCAATCCTGACACTGAAA
TATGCACAAAGGATGGTGAAACGCCACTTATAAAGGCTACCAAGATGAGAAACATTGAAGTGGTGGAGCTGCTGCTAGATAAAGGTGCTA
AAGTGTCTGCTGTAGATAAGAAAGGAGATACTCCCTTGCATATTGCTATTCGTGGAAGGAGCCGGAAACTGGCAGAACTGCTTTTAAGAA
ATCCCAAAGATGGGCGATTACTTTATAGGCCCAACAAAGCAGGCGAGACTCCTTATAATATTGACTGTAGCCATCAGAAGAGTATTTTAA
CTCAAATATTTGGAGCCAGACACTTGTCTCCTACTGAAACAGACGGTGACATGCTTGGATATGATTTATATAGCAGTGCCCTGGCAGATA
TTCTCAGTGAGCCTACCATGCAGCCACCCATTTGTGTGGGGTTATATGCACAGTGGGGAAGTGGGAAATCTTTCTTACTCAAGAAACTAG
AAGACGAAATGAAAACCTTCGCCGGACAACAGATTGAGCCTCTCTTTCAGTTCTCATGGCTCATAGTGTTTCTTACCCTGCTACTTTGTG
GAGGGCTTGGTTTATTGTTTGCCTTCACGGTCCACCCAAATCTTGGAATAGCAGTGTCACTGAGCTTCTTGGCTCTCTTATATATATTCT
TTATTGTCATTTACTTTGGTGGACGAAGAGAAGGAGAGAGTTGGAATTGGGCCTGGGTCCTCAGCACTAGATTGGCAAGACATATTGGAT
ATTTGGAACTCCTCCTTAAATTGATGTTTGTGAATCCACCTGAGTTGCCAGAGCAGACTACTAAAGCTTTACCTGTGAGGTTTTTGTTTA
CAGATTACAATAGACTGTCCAGTGTAGGTGGAGAAACTTCTCTGGCTGAAATGATTGCAACCCTCTCGGATGCTTGTGAAAGAGAGTTTG
GCTTTTTGGCAACCAGGCTTTTTCGAGTATTCAAGACTGAAGATACTCAGGGTAAAAAGAAATGGAAAAAAACATGTTGTCTCCCATCTT
TTGTCATCTTCCTTTTTATCATTGGCTGCATTATATCTGGAATTACTCTTCTGGCTATATTTAGAGTTGACCCAAAGCATCTGACTGTAA
ATGCTGTCCTCATATCAATCGCATCTGTAGTGGGATTGGCCTTTGTGTTGAACTGTCGTACATGGTGGCAAGTGCTGGACTCGCTCCTGA
ATTCCCAAAGAAAACGCCTCCATAATGCAGCCTCCAAACTGCACAAATTGAAAAGTGAAGGATTCATGAAAGTTCTTAAATGTGAAGTGG
AATTGATGGCCAGGATGGCAAAAACCATTGACAGCTTCACTCAGAATCAGACAAGGCTGGTGGTCATCATCGATGGATTAGATGCCTGTG
AGCAGGACAAAGTCCTTCAGATGCTGGACACTGTCCGAGTTCTGTTTTCAAAAGGCCCGTTCATTGCCATTTTTGCAAGTGATCCACATA
TTATCATAAAGGCAATTAACCAGAACCTCAATAGTGTGCTTCGGGATTCAAATATAAATGGCCATGACTACATGCGCAACATAGTCCACT
TGCCTGTGTTCCTTAATAGTCGTGGACTAAGCAATGCAAGAAAATTTCTCGTAACTTCAGCAACAAATGGAGACGTTCCATGCTCAGATA
CTACAGGGATACAGGAAGATGCTGACAGAAGAGTTTCACAGAACAGCCTTGGGGAGATGACAAAACTTGGTAGCAAGACAGCCCTCAATA
GACGGGACACTTACCGAAGAAGGCAGATGCAGAGGACCATCACTCGCCAGATGTCCTTTGATCTTACAAAACTGCTGGTTACCGAGGACT
GGTTCAGTGACATCAGTCCCCAGACCATGAGAAGATTACTTAATATTGTTTCTGTGACAGGACGATTACTGAGAGCCAATCAGATTAGTT
TCAACTGGGACAGGCTTGCTAGCTGGATCAACCTTACTGAGCAGTGGCCATACCGGACTTCATGGCTCATATTATATTTGGAAGAGACTG
AAGGTATTCCAGATCAAATGACATTAAAAACCATCTACGAAAGAATATCAAAGAATATTCCAACAACTAAGGATGTTGAGCCACTTCTTG
AAATTGATGGAGATATAAGAAATTTTGAAGTGTTTTTGTCTTCAAGGACCCCAGTTCTTGTGGCTCGAGATGTAAAAGTCTTTTTGCCAT
GCACTGTAAACCTAGATCCCAAACTACGGGAAATTATTGCAGATGTTCGTGCTGCCAGAGAGCAGATCAGTATTGGAGGACTGGCGTACC
CCCCGCTCCCTCTACATGAGGGTCCTCCTAGGGCGCCATCAGGGTACAGCCAGCCCCCATCCGTGTGCTCTTCCACGTCCTTCAATGGGC
CCTTCGCAGGTGGAGTGGTGTCACCACAGCCTCACAGCAGCTATTACAGCGGCATGACGGGCCCTCAGCATCCCTTCTACAACAGGGTCG
GCGGAAGCAGAAGTGGGCTGTGGATCCTCAGAACACTGCCTGGAGTAATGACGATTCCAAGTTTGGCCAGCGGATGCTAGAGAAGATGGG
GTGGTCTAAAGGAAAGGGTTTAGGGGCTCAGGAGCAAGGAGCCACAGATCATATTAAAGTTCAAGTGAAAAATAACCACCTGGGACTCGG
AGCTACCATCAATAATGAAGACAACTGGATTGCCCATCAGGATGATTTTAACCAGCTTCTGGCCGAACTGAACACTTGCCATGGGCAGGA
AACCACAGATTCCTCGGACAAGAAGGAAAAGAAATCTTTTAGCCTTGAGGAAAAGTCCAAAATCTCCAAAAACCGTGTTCACTATATGAA
ATTCACAAAAGGGCGATGCCAGTCCCTCCACTCCAGAGGAGAACGAAACCACGACAACCAGCGCCTTCACCATCCAGGAGTACTTTGCCA
AGCGGATGGCAGCACTGAAGAACAAGCCCCAGGTTCCAGTTCCAGGGTCTGACATTTCTGAGACGCAGGTGGAACGTAAAAGGGGGAAGA
AAAGAAATAAAGAGGCCACAGGTAAAGATGTGGAAAGTTACCTCCAGCCTAAGGCCAAGAGGCACACGGAGGGAAAGCCCGAGAGGGCCG
AGGCCCAGGAGCGAGTGGCCAAGAAGAAGAGCGCGCCAGCAGAAGAGCAGCTCAGAGGCCCCTGCTGGGACCAGAGTTCCAAGGCCTCTG
CTCAGGATGCAGGGGACCATGTGCAGCCGCCTGAGGGCCGGGACTTCACCCTGAAGCCCAAAAAGAGGAGAGGGAAGAAAAAGCTGCAAA
AACCAGTAGAGATAGCAGAGGACGCTACACTAGAAGAAACGCTAGTGAAAAAGAAGAAGAAGAAAGATTCCAAATGAATCCTTCCCAGCC
GGGGCCTTCCGACCACTCAGCTGTCAGGGCACTGCGGGGGCAGACACCTCTGGCCTGAAGTCACAGCAGAGTTCACCCCAGAGCGCCTGG
GCGCATCTTGTGGCATGCCCATGGGCTGCCGAGTCCTGCCCTCTCGCCACATTTCCCCCAAGTTACATTCCCAGGAGGACCTTTTTAATG
TTCTCAATCGTGGCTCTCAGACACAAATAAATTTTTTTGTAAACTCTGAGCCCTTCAGCAAGAGAGTTTAATTATAATCATTACAAATAC
ATGCATTCATGTAAGTGTGCACACGTGTGTGTGCATGTGCGCATCTGTGTGTGTGTGTGTGTGTCACTATCTCCGTTTGCTCTCGGTTCC

>In-frame_KIDINS220_ENST00000418530_chr2_8890242_-_PINX1_ENST00000519088_chr8_10692285_-_4729nt
ACGTGATCTGTCAGTTCGCGGAGAGGGAAGAATATGGCCGCCGGGTGTGGTGAGGGCGACGCGCTTGCAGTCGCCGTCTCTTGCTTCCCC
GTCCTCTGACATCGCCTGCAGCCGAGCGGGCCCGTTCCGCCGGAGCTGAGGACCAGGTATTCAAATAAAGTTAATTGCAGCTTTCTGTGA
AAATGTCAGTTTTGATATCACAGAGCGTCATAAATTATGTAGAGGAAGAAAACATTCCTGCTCTGAAAGCTCTTCTTGAAAAATGCAAAG
ATGTAGATGAGAGAAATGAGTGTGGCCAGACTCCACTGATGATAGCTGCCGAACAAGGCAATCTGGAAATAGTGAAGGAATTAATTAAGA
ATGGAGCTAACTGCAATCTGGAAGATTTGGATAATTGGACAGCACTTATATCTGCATCGAAAGAAGGGCATGTGCACATCGTAGAGGAAC
TACTGAAATGTGGGGTTAACTTGGAGCACCGTGATATGGGAGGATGGACAGCTCTTATGTGGGCATGTTACAAAGGCCGTACTGACGTAG
TAGAGTTGCTTCTTTCTCATGGTGCCAATCCAAGTGTCACTGGTCTGTACAGTGTTTACCCAATCATTTGGGCAGCAGGGAGAGGCCATG
CAGATATAGTTCATCTTTTACTGCAAAATGGTGCTAAAGTCAACTGCTCTGATAAGTATGGAACCACCCCTTTAGTTTGGGCTGCACGAA
AGGGTCATTTGGAATGTGTGAAACATTTATTGGCCATGGGAGCTGATGTGGATCAAGAAGGAGCTAATTCAATGACTGCACTTATTGTGG
CAGTGAAAGGAGGTTACACACAGTCAGTAAAAGAAATTTTGAAGAGGAATCCAAATGTAAACTTAACAGATAAAGATGGAAATACAGCTT
TGATGATTGCATCAAAGGAGGGACATACGGAGATTGTGCAGGATCTGCTCGACGCTGGAACATATGTGAACATACCTGACAGGAGTGGGG
ATACTGTGTTGATTGGCGCTGTCAGAGGTGGTCATGTTGAAATTGTTCGAGCGCTTCTCCAAAAATATGCTGATATAGACATTAGAGGAC
AGGATAATAAAACTGCTTTGTATTGGGCTGTTGAGAAAGGAAATGCAACAATGGTGAGAGATATCTTACAGTGCAATCCTGACACTGAAA
TATGCACAAAGGATGGTGAAACGCCACTTATAAAGGCTACCAAGATGAGAAACATTGAAGTGGTGGAGCTGCTGCTAGATAAAGGTGCTA
AAGTGTCTGCTGTAGATAAGAAAGGAGATACTCCCTTGCATATTGCTATTCGTGGAAGGAGCCGGAAACTGGCAGAACTGCTTTTAAGAA
ATCCCAAAGATGGGCGATTACTTTATAGGCCCAACAAAGCAGGCGAGACTCCTTATAATATTGACTGTAGCCATCAGAAGAGTATTTTAA
CTCAAATATTTGGAGCCAGACACTTGTCTCCTACTGAAACAGACGGTGACATGCTTGGATATGATTTATATAGCAGTGCCCTGGCAGATA
TTCTCAGTGAGCCTACCATGCAGCCACCCATTTGTGTGGGGTTATATGCACAGTGGGGAAGTGGGAAATCTTTCTTACTCAAGAAACTAG
AAGACGAAATGAAAACCTTCGCCGGACAACAGATTGAGCCTCTCTTTCAGTTCTCATGGCTCATAGTGTTTCTTACCCTGCTACTTTGTG
GAGGGCTTGGTTTATTGTTTGCCTTCACGGTCCACCCAAATCTTGGAATAGCAGTGTCACTGAGCTTCTTGGCTCTCTTATATATATTCT
TTATTGTCATTTACTTTGGTGGACGAAGAGAAGGAGAGAGTTGGAATTGGGCCTGGGTCCTCAGCACTAGATTGGCAAGACATATTGGAT
ATTTGGAACTCCTCCTTAAATTGATGTTTGTGAATCCACCTGAGTTGCCAGAGCAGACTACTAAAGCTTTACCTGTGAGGTTTTTGTTTA
CAGATTACAATAGACTGTCCAGTGTAGGTGGAGAAACTTCTCTGGCTGAAATGATTGCAACCCTCTCGGATGCTTGTGAAAGAGAGTTTG
GCTTTTTGGCAACCAGGCTTTTTCGAGTATTCAAGACTGAAGATACTCAGGGTAAAAAGAAATGGAAAAAAACATGTTGTCTCCCATCTT
TTGTCATCTTCCTTTTTATCATTGGCTGCATTATATCTGGAATTACTCTTCTGGCTATATTTAGAGTTGACCCAAAGCATCTGACTGTAA
ATGCTGTCCTCATATCAATCGCATCTGTAGTGGGATTGGCCTTTGTGTTGAACTGTCGTACATGGTGGCAAGTGCTGGACTCGCTCCTGA
ATTCCCAAAGAAAACGCCTCCATAATGCAGCCTCCAAACTGCACAAATTGAAAAGTGAAGGATTCATGAAAGTTCTTAAATGTGAAGTGG
AATTGATGGCCAGGATGGCAAAAACCATTGACAGCTTCACTCAGAATCAGACAAGGCTGGTGGTCATCATCGATGGATTAGATGCCTGTG
AGCAGGACAAAGTCCTTCAGATGCTGGACACTGTCCGAGTTCTGTTTTCAAAAGGCCCGTTCATTGCCATTTTTGCAAGTGATCCACATA
TTATCATAAAGGCAATTAACCAGAACCTCAATAGTGTGCTTCGGGATTCAAATATAAATGGCCATGACTACATGCGCAACATAGTCCACT
TGCCTGTGTTCCTTAATAGTCGTGGACTAAGCAATGCAAGAAAATTTCTCGTAACTTCAGCAACAAATGGAGACGTTCCATGCTCAGATA
CTACAGGGATACAGGAAGATGCTGACAGAAGAGTTTCACAGAACAGCCTTGGGGAGATGACAAAACTTGGTAGCAAGACAGCCCTCAATA
GACGGGACACTTACCGAAGAAGGCAGATGCAGAGGACCATCACTCGCCAGATGTCCTTTGATCTTACAAAACTGCTGGTTACCGAGGACT
GGTTCAGTGACATCAGTCCCCAGACCATGAGAAGATTACTTAATATTGTTTCTGTGACAGGACGATTACTGAGAGCCAATCAGATTAGTT
TCAACTGGGACAGGCTTGCTAGCTGGATCAACCTTACTGAGCAGTGGCCATACCGGACTTCATGGCTCATATTATATTTGGAAGAGACTG
AAGGTATTCCAGATCAAATGACATTAAAAACCATCTACGAAAGAATATCAAAGAATATTCCAACAACTAAGGATGTTGAGCCACTTCTTG
AAATTGATGGAGATATAAGAAATTTTGAAGTGTTTTTGTCTTCAAGGACCCCAGTTCTTGTGGCTCGAGATGTAAAAGTCTTTTTGCCAT
GCACTGTAAACCTAGATCCCAAACTACGGGAAATTATTGCAGATGTTCGTGCTGCCAGAGAGCAGATCAGTATTGGAGGACTGGCGTACC
CCCCGCTCCCTCTACATGAGGGTCCTCCTAGGGCGCCATCAGGGTACAGCCAGCCCCCATCCGTGTGCTCTTCCACGTCCTTCAATGGGC
CCTTCGCAGGTGGAGTGGTGTCACCACAGCCTCACAGCAGCTATTACAGCGGCATGACGGGCCCTCAGCATCCCTTCTACAACAGGGTCG
GCGGAAGCAGAAGTGGGCTGTGGATCCTCAGAACACTGCCTGGAGTAATGACGATTCCAAGTTTGGCCAGCGGATGCTAGAGAAGATGGG
GTGGTCTAAAGGAAAGGGTTTAGGGGCTCAGGAGCAAGGAGCCACAGATCATATTAAAGTTCAAGTGAAAAATAACCACCTGGGACTCGG
AGCTACCATCAATAATGAAGACAACTGGATTGCCCATCAGGATGATTTTAACCAGCTTCTGGCCGAACTGAACACTTGCCATGGGCAGGA
AACCACAGATTCCTCGGACAAGAAGGAAAAGAAATCTTTTAGCCTTGAGGAAAAGTCCAAAATCTCCAAAAACCGTGTTCACTATATGAA
ATTCACAAAAGGGCGATGCCAGTCCCTCCACTCCAGAGGAGAACGAAACCACGACAACCAGCGCCTTCACCATCCAGGAGTACTTTGCCA
AGCGGATGGCAGCACTGAAGAACAAGCCCCAGGTTCCAGTTCCAGGGTCTGACATTTCTGAGACGCAGGTGGAACGTAAAAGGGGGAAGA
AAAGAAATAAAGAGGCCACAGGTAAAGATGTGGAAAGTTACCTCCAGCCTAAGGCCAAGAGGCACACGGAGGGAAAGCCCGAGAGGGCCG
AGGCCCAGGAGCGAGTGGCCAAGAAGAAGAGCGCGCCAGCAGAAGAGCAGCTCAGAGGCCCCTGCTGGGACCAGAGTTCCAAGGCCTCTG
CTCAGGATGCAGGGGACCATGTGCAGCCGCCTGAGGGCCGGGACTTCACCCTGAAGCCCAAAAAGAGGAGAGGGAAGAAAAAGCTGCAAA
AACCAGTAGAGATAGCAGAGGACGCTACACTAGAAGAAACGCTAGTGAAAAAGAAGAAGAAGAAAGATTCCAAATGAATCCTTCCCAGCC
GGGGCCTTCCGACCACTCAGCTGTCAGGGCACTGCGGGGGCAGACACCTCTGGCCTGAAGTCACAGCAGAGTTCACCCCAGAGCGCCTGG
GCGCATCTTGTGGCATGCCCATGGGCTGCCGAGTCCTGCCCTCTCGCCACATTTCCCCCAAGTTACATTCCCAGGAGGACCTTTTTAATG


Top

FusionGenePPI for KIDINS220_PINX1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page

.

check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors
KIDINS220MOB4, FN1, MYC, LGR4, HLA-DPA1, CEACAM21, CGRRF1, TXNDC15, VSIG4, EVA1C, FAF2, LDLRAD4, NTRK1, TMEM17, CLTC, GAK, KIF5B, PTPN1, RAB5C, RAB7A, RAB11A, VAPA, ATP6AP2, MYEF2, GOLT1B, GTSE1, CDH1, XPR1, FGFR2, VSIG1, MRAP2, B4GAT1, CLMP, MAGEE1, CD79B, TNFRSF1A, DKKL1, CDH5, MANSC1, PDHA1PINX1MCRS1, PLEKHJ1, PABPC1, TXN, RPS10, HRNR, RPL31, RPS3A, RPS19, RPL23A, GTPBP4, RPS28, CALM3, PABPC4, RPS16, AHCY, CAPRIN1, PAFAH1B2, TERF1, TERT, AIDA, DHX15, CACYBP, GABPA, TP63, EAF1, FBL, ALB, FXR1, FAM98A, PPP2R2D, APP, HIST1H2BG, HIST1H3A, HNRNPD, NOP56, SGTB, CDC14B, CCRN4L, SNRNP70, WDYHV1, DGCR8, RPL8, FOXA1


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


Top

RelatedDrugs for KIDINS220_PINX1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

Top

RelatedDiseases for KIDINS220_PINX1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource