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Fusion gene ID: 18723 |
FusionGeneSummary for KIAA1549_BRAF |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: KIAA1549_BRAF | Fusion gene ID: 18723 | Hgene | Tgene | Gene symbol | KIAA1549 | BRAF | Gene ID | 57670 | 673 |
| Gene name | KIAA1549 | B-Raf proto-oncogene, serine/threonine kinase | |
| Synonyms | - | B-RAF1|B-raf|BRAF1|NS7|RAFB1 | |
| Cytomap | 7q34 | 7q34 | |
| Type of gene | protein-coding | protein-coding | |
| Description | UPF0606 protein KIAA1549 | serine/threonine-protein kinase B-raf94 kDa B-raf proteinB-Raf proto-oncogene serine/threonine-protein kinase (p94)B-Raf serine/threonine-proteinmurine sarcoma viral (v-raf) oncogene homolog B1proto-oncogene B-Rafv-raf murine sarcoma viral oncogene | |
| Modification date | 20180519 | 20180527 | |
| UniProtAcc | Q9HCM3 | P15056 | |
| Ensembl transtripts involved in fusion gene | ENST00000242365, ENST00000440172, ENST00000422774, | ENST00000288602, | |
| Fusion gene scores | * DoF score | 4 X 5 X 3=60 | 24 X 11 X 10=2640 |
| # samples | 8 | 35 | |
| ** MAII score | log2(8/60*10)=0.415037499278844 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | log2(35/2640*10)=-2.91511110241349 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: KIAA1549 [Title/Abstract] AND BRAF [Title/Abstract] AND fusion [Title/Abstract] Oncogenic RAF1 rearrangement and a novel BRAF mutation as alternatives to KIAA1549:BRAF fusion in activating the MAPK pathway in pilocytic astrocytoma. (pmid: 19363522) | ||
| Functional or gene categories assigned by FusionGDB annotation | Oncogene involved fusion gene, in-frame and retained their domain. Kinase involved fusion gene, inframe and retained kinase domain. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Tgene | BRAF | GO:0006468 | protein phosphorylation | 17563371 |
| Tgene | BRAF | GO:0010828 | positive regulation of glucose transmembrane transport | 23010278 |
| Tgene | BRAF | GO:0033138 | positive regulation of peptidyl-serine phosphorylation | 19667065 |
| Tgene | BRAF | GO:0043066 | negative regulation of apoptotic process | 19667065 |
| Tgene | BRAF | GO:0070374 | positive regulation of ERK1 and ERK2 cascade | 22065586 |
| Tgene | BRAF | GO:0071277 | cellular response to calcium ion | 18567582 |
| Tgene | BRAF | GO:0090150 | establishment of protein localization to membrane | 23010278 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | LGG | TCGA-HT-7691-01A | KIAA1549 | chr7 | 138545885 | - | BRAF | chr7 | 140487384 | - |
| ChiTaRS3.1 | AM989472 | KIAA1549 | chr7 | 138545884 | - | BRAF | chr7 | 140487384 | - | ||
| ChiTaRS3.1 | AM989475 | KIAA1549 | chr7 | 138545884 | - | BRAF | chr7 | 140487384 | - | ||
| ChiTaRS3.1 | AM989477 | KIAA1549 | chr7 | 138552720 | - | BRAF | chr7 | 140487384 | - | ||
| ChiTaRS3.1 | AM989474 | KIAA1549 | chr7 | 138552720 | - | BRAF | chr7 | 140487384 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000242365 | ENST00000288602 | KIAA1549 | chr7 | 138545885 | - | BRAF | chr7 | 140487384 | - |
| In-frame | ENST00000440172 | ENST00000288602 | KIAA1549 | chr7 | 138545885 | - | BRAF | chr7 | 140487384 | - |
| In-frame | ENST00000422774 | ENST00000288602 | KIAA1549 | chr7 | 138545885 | - | BRAF | chr7 | 140487384 | - |
| In-frame | ENST00000242365 | ENST00000288602 | KIAA1549 | chr7 | 138545884 | - | BRAF | chr7 | 140487384 | - |
| In-frame | ENST00000440172 | ENST00000288602 | KIAA1549 | chr7 | 138545884 | - | BRAF | chr7 | 140487384 | - |
| In-frame | ENST00000422774 | ENST00000288602 | KIAA1549 | chr7 | 138545884 | - | BRAF | chr7 | 140487384 | - |
| In-frame | ENST00000242365 | ENST00000288602 | KIAA1549 | chr7 | 138552720 | - | BRAF | chr7 | 140487384 | - |
| In-frame | ENST00000440172 | ENST00000288602 | KIAA1549 | chr7 | 138552720 | - | BRAF | chr7 | 140487384 | - |
| In-frame | ENST00000422774 | ENST00000288602 | KIAA1549 | chr7 | 138552720 | - | BRAF | chr7 | 140487384 | - |
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FusionProtFeatures for KIAA1549_BRAF |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| KIAA1549 | BRAF |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | KIAA1549 | chr7:138545884 | chr7:140487384 | ENST00000422774 | - | 16 | 20 | 494_764 | 1749 | 1951 | Compositional bias | Note=Ser-rich |
| Hgene | KIAA1549 | chr7:138545884 | chr7:140487384 | ENST00000440172 | - | 16 | 20 | 494_764 | 1749 | 1935 | Compositional bias | Note=Ser-rich |
| Hgene | KIAA1549 | chr7:138545885 | chr7:140487384 | ENST00000422774 | - | 16 | 20 | 494_764 | 1749 | 1951 | Compositional bias | Note=Ser-rich |
| Hgene | KIAA1549 | chr7:138545885 | chr7:140487384 | ENST00000440172 | - | 16 | 20 | 494_764 | 1749 | 1935 | Compositional bias | Note=Ser-rich |
| Hgene | KIAA1549 | chr7:138552720 | chr7:140487384 | ENST00000422774 | - | 15 | 20 | 494_764 | 1643 | 1951 | Compositional bias | Note=Ser-rich |
| Hgene | KIAA1549 | chr7:138552720 | chr7:140487384 | ENST00000440172 | - | 15 | 20 | 494_764 | 1643 | 1935 | Compositional bias | Note=Ser-rich |
| Hgene | KIAA1549 | chr7:138545884 | chr7:140487384 | ENST00000422774 | - | 16 | 20 | 1299_1319 | 1749 | 1951 | Transmembrane | Helical |
| Hgene | KIAA1549 | chr7:138545884 | chr7:140487384 | ENST00000422774 | - | 16 | 20 | 998_1018 | 1749 | 1951 | Transmembrane | Helical |
| Hgene | KIAA1549 | chr7:138545884 | chr7:140487384 | ENST00000440172 | - | 16 | 20 | 1299_1319 | 1749 | 1935 | Transmembrane | Helical |
| Hgene | KIAA1549 | chr7:138545884 | chr7:140487384 | ENST00000440172 | - | 16 | 20 | 998_1018 | 1749 | 1935 | Transmembrane | Helical |
| Hgene | KIAA1549 | chr7:138545885 | chr7:140487384 | ENST00000422774 | - | 16 | 20 | 1299_1319 | 1749 | 1951 | Transmembrane | Helical |
| Hgene | KIAA1549 | chr7:138545885 | chr7:140487384 | ENST00000422774 | - | 16 | 20 | 998_1018 | 1749 | 1951 | Transmembrane | Helical |
| Hgene | KIAA1549 | chr7:138545885 | chr7:140487384 | ENST00000440172 | - | 16 | 20 | 1299_1319 | 1749 | 1935 | Transmembrane | Helical |
| Hgene | KIAA1549 | chr7:138545885 | chr7:140487384 | ENST00000440172 | - | 16 | 20 | 998_1018 | 1749 | 1935 | Transmembrane | Helical |
| Hgene | KIAA1549 | chr7:138552720 | chr7:140487384 | ENST00000422774 | - | 15 | 20 | 1299_1319 | 1643 | 1951 | Transmembrane | Helical |
| Hgene | KIAA1549 | chr7:138552720 | chr7:140487384 | ENST00000422774 | - | 15 | 20 | 998_1018 | 1643 | 1951 | Transmembrane | Helical |
| Hgene | KIAA1549 | chr7:138552720 | chr7:140487384 | ENST00000440172 | - | 15 | 20 | 1299_1319 | 1643 | 1935 | Transmembrane | Helical |
| Hgene | KIAA1549 | chr7:138552720 | chr7:140487384 | ENST00000440172 | - | 15 | 20 | 998_1018 | 1643 | 1935 | Transmembrane | Helical |
| Tgene | >BRAF | chr7:138545884 | chr7:140487384 | ENST00000288602 | - | 7 | 18 | 428_432 | 380 | 767 | Compositional bias | Note=Poly-Ser |
| Tgene | >BRAF | chr7:138545885 | chr7:140487384 | ENST00000288602 | - | 7 | 18 | 428_432 | 380 | 767 | Compositional bias | Note=Poly-Ser |
| Tgene | >BRAF | chr7:138552720 | chr7:140487384 | ENST00000288602 | - | 7 | 18 | 428_432 | 380 | 767 | Compositional bias | Note=Poly-Ser |
| Tgene | >BRAF | chr7:138545884 | chr7:140487384 | ENST00000288602 | - | 7 | 18 | 457_717 | 380 | 767 | Domain | Protein kinase |
| Tgene | >BRAF | chr7:138545885 | chr7:140487384 | ENST00000288602 | - | 7 | 18 | 457_717 | 380 | 767 | Domain | Protein kinase |
| Tgene | >BRAF | chr7:138552720 | chr7:140487384 | ENST00000288602 | - | 7 | 18 | 457_717 | 380 | 767 | Domain | Protein kinase |
| Tgene | >BRAF | chr7:138545884 | chr7:140487384 | ENST00000288602 | - | 7 | 18 | 463_471 | 380 | 767 | Nucleotide binding | ATP |
| Tgene | >BRAF | chr7:138545885 | chr7:140487384 | ENST00000288602 | - | 7 | 18 | 463_471 | 380 | 767 | Nucleotide binding | ATP |
| Tgene | >BRAF | chr7:138552720 | chr7:140487384 | ENST00000288602 | - | 7 | 18 | 463_471 | 380 | 767 | Nucleotide binding | ATP |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | BRAF | chr7:138545884 | chr7:140487384 | ENST00000288602 | - | 7 | 18 | 122_129 | 380 | 767 | Compositional bias | Note=Poly-Ser |
| Tgene | BRAF | chr7:138545884 | chr7:140487384 | ENST00000288602 | - | 7 | 18 | 6_11 | 380 | 767 | Compositional bias | Note=Poly-Gly |
| Tgene | BRAF | chr7:138545885 | chr7:140487384 | ENST00000288602 | - | 7 | 18 | 122_129 | 380 | 767 | Compositional bias | Note=Poly-Ser |
| Tgene | BRAF | chr7:138545885 | chr7:140487384 | ENST00000288602 | - | 7 | 18 | 6_11 | 380 | 767 | Compositional bias | Note=Poly-Gly |
| Tgene | BRAF | chr7:138552720 | chr7:140487384 | ENST00000288602 | - | 7 | 18 | 122_129 | 380 | 767 | Compositional bias | Note=Poly-Ser |
| Tgene | BRAF | chr7:138552720 | chr7:140487384 | ENST00000288602 | - | 7 | 18 | 6_11 | 380 | 767 | Compositional bias | Note=Poly-Gly |
| Tgene | BRAF | chr7:138545884 | chr7:140487384 | ENST00000288602 | - | 7 | 18 | 155_227 | 380 | 767 | Domain | RBD |
| Tgene | BRAF | chr7:138545885 | chr7:140487384 | ENST00000288602 | - | 7 | 18 | 155_227 | 380 | 767 | Domain | RBD |
| Tgene | BRAF | chr7:138552720 | chr7:140487384 | ENST00000288602 | - | 7 | 18 | 155_227 | 380 | 767 | Domain | RBD |
| Tgene | BRAF | chr7:138545884 | chr7:140487384 | ENST00000288602 | - | 7 | 18 | 234_280 | 380 | 767 | Zinc finger | Phorbol-ester/DAG-type |
| Tgene | BRAF | chr7:138545885 | chr7:140487384 | ENST00000288602 | - | 7 | 18 | 234_280 | 380 | 767 | Zinc finger | Phorbol-ester/DAG-type |
| Tgene | BRAF | chr7:138552720 | chr7:140487384 | ENST00000288602 | - | 7 | 18 | 234_280 | 380 | 767 | Zinc finger | Phorbol-ester/DAG-type |
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FusionGeneSequence for KIAA1549_BRAF |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_KIAA1549_ENST00000242365_chr7_138545885_-_BRAF_ENST00000288602_chr7_140487384_-_2086aa MHCTNPALIFLIDELSPEQHNLSLYSMELVLKKSTGHSAAQVALTETAPGSQHSSPLHVTAPPSATTFDTAFFNQGKQTKSTADPSIFVA TYVSVTSKEVAVNDDEMDNFLPDTHWTTPRMVSPIQYITVSPPGLPREALEPMLTPSLPMVSLQDEEVTSGWQNTTRQPAAYAESASHFH TFRSAFRTSEGIVPTPGRNLVLYPTDAYSHLSSRTLPEIVASLTEGVETTLFLSSRSLMPQPLGDGITIPLPSLGEVSQPPEEVWATSAD RYTDVTTVLSQSLEETISPRTYPTVTASHAALAFSRTHSPLLSTPLAFASSASPTDVSSNPFLPSDSSKTSELHSNSALPGPVDNTHILS PVSSFRPYTWCAACTVPSPQQVLATSLMEKDVGSGDGAETLCMTVLEESSISLMSSVVADFSEFEEDPQVFNTLFPSRPIVPLSSRSMEI SETSVGISAEVDMSSVTTTQVPPAHGRLSVPASLDPTAGSLSVAETQVTPSSVTTAFFSVITSILLDSSFSVIANKNTPSLAVRDPSVFT PYSLVPSVESSLFSDQERSSFSEHKPRGALDFASSFFSTPPLELSGSISSPSEAPASLSLMPSDLSPFTSQSFSPLVETFTLFDSSDLQS SQLSLPSSTNLEFSQLQPSSELPLNTIMLLPSRSEVSPWSSFPSDSLEFVEASTVSLTDSEAHFTSAFIETTSYLESSLISHESAVTALV PPGSESFDILTAGIQATSPLTTVHTTPILTESSLFSTLTPPDDQISALDGHVSVLASFSKAIPTGTVLITDAYLPSGSSFVSEATPFPLP TELTVVGPSLTPTEVPLNTSTEVSTTSTGAATGGPLDSTLMGDAASQSPPESSAAPPLPSLRPVTAFTLEATVDTPTLATAKPPYVCDIT VPDAYLITTVLARRAVQEYIITAIKEVLRIHFNRAVELKVYELFTDFTFLVTSGPFVYTAISVINVLINSKLVRDQTPLILSVKPSFLVP ESRFQVQTVLQFVPPSVDTGFCNFTQRIEKGLMTALFEVRKHHQGTYNLTVQILNITISSSRVTPRRGPVNIIFAVKSTQGFLNGSEVSE LLRNLSVVEFSFYLGYPVLQIAEPFQYPQLNLSQLLKSSWVRTVLLGVMEKQLQNEVFQAEMERKLAQLLSEVSTRRRMWRRATVAAGNS VVQVVNVSRLEGDDNPVQLIYFVEDQDGERLSAVKSSDLINKMDLQRAAIILGYRIQGVIAQPVDRVKRPSPESQSNNLWVIVGVVIPVL VVMVIVVILYWKLCRTDKLDFQPDTVANIQQRQKLQIPSVKGFDFAKQHLGQHNKDDILIIHEPAPLPGPLKDHTTPSENGDVPSPKSKI PSKNVRHRGRVSPSDADSTVSEESSERDAGDKTPGAVNDGRSHRAPQSGPPLPSSGNEQHSSASIFEHVDRISRPPEASRRVPSKIQLIA MQPIPAPPVQRPSPADRVAESNKINKEIQTALRHKSEIEHHRNKIRLRAKRRGHYEFPVVDDLSSGDTKERHRVYRRAQMQIDKILDPTA SVPSVFIEPRKSSRIKRSPKPRRKHQVNGCPADAEKDRLITTDSDGTYRRPPGVHNSAYIGCPSDPDLPADVQTPSSVELGRYPALPFPA SQYIPPQPSIEEARQTMHSLLDDAFALVAPSSQPASTAGVGPGVPPGLPANSTPSQEERRATQWGSFYSPAQTANNPCSDLIRDQGFRGD GGSTTGLSATPPASLPGSLTNVKALQKSPGPQRERKSSSSSEDRNRMKTLGRRDSSDDWEIPDGQITVGQRIGSGSFGTVYKGKWHGDVA VKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGYSTKPQLAIVTQWCEGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDYLHAKS IIHRDLKSNNIFLHEDLTVKIGDFGLATVKSRWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYSNINN RDQIIFMVGRGYLSPDLSKVRSNCPKAMKRLMAECLKKKRDERPLFPQILASIELLARSLPKIHRSASEPSLNRAGFQTEDFSLYACASP >In-frame_KIAA1549_ENST00000440172_chr7_138545885_-_BRAF_ENST00000288602_chr7_140487384_-_2136aa MPGARRRRRGAAMEGKPRAGVALAPGPSGRRPSARCARRRRPGLLLPGLWLLLLARPASCAPDELSPEQHNLSLYSMELVLKKSTGHSAA QVALTETAPGSQHSSPLHVTAPPSATTFDTAFFNQGKQTKSTADPSIFVATYVSVTSKEVAVNDDEMDNFLPDTHWTTPRMVSPIQYITV SPPGLPREALEPMLTPSLPMVSLQDEEVTSGWQNTTRQPAAYAESASHFHTFRSAFRTSEGIVPTPGRNLVLYPTDAYSHLSSRTLPEIV ASLTEGVETTLFLSSRSLMPQPLGDGITIPLPSLGEVSQPPEEVWATSADRYTDVTTVLSQSLEETISPRTYPTVTASHAALAFSRTHSP LLSTPLAFASSASPTDVSSNPFLPSDSSKTSELHSNSALPGPVDNTHILSPVSSFRPYTWCAACTVPSPQQVLATSLMEKDVGSGDGAET LCMTVLEESSISLMSSVVADFSEFEEDPQVFNTLFPSRPIVPLSSRSMEISETSVGISAEVDMSSVTTTQVPPAHGRLSVPASLDPTAGS LSVAETQVTPSSVTTAFFSVITSILLDSSFSVIANKNTPSLAVRDPSVFTPYSLVPSVESSLFSDQERSSFSEHKPRGALDFASSFFSTP PLELSGSISSPSEAPASLSLMPSDLSPFTSQSFSPLVETFTLFDSSDLQSSQLSLPSSTNLEFSQLQPSSELPLNTIMLLPSRSEVSPWS SFPSDSLEFVEASTVSLTDSEAHFTSAFIETTSYLESSLISHESAVTALVPPGSESFDILTAGIQATSPLTTVHTTPILTESSLFSTLTP PDDQISALDGHVSVLASFSKAIPTGTVLITDAYLPSGSSFVSEATPFPLPTELTVVGPSLTPTEVPLNTSTEVSTTSTGAATGGPLDSTL MGDAASQSPPESSAAPPLPSLRPVTAFTLEATVDTPTLATAKPPYVCDITVPDAYLITTVLARRAVQEYIITAIKEVLRIHFNRAVELKV YELFTDFTFLVTSGPFVYTAISVINVLINSKLVRDQTPLILSVKPSFLVPESRFQVQTVLQFVPPSVDTGFCNFTQRIEKGLMTALFEVR KHHQGTYNLTVQILNITISSSRVTPRRGPVNIIFAVKSTQGFLNGSEVSELLRNLSVVEFSFYLGYPVLQIAEPFQYPQLNLSQLLKSSW VRTVLLGVMEKQLQNEVFQAEMERKLAQLLSEVSTRRRMWRRATVAAGNSVVQVVNVSRLEGDDNPVQLIYFVEDQDGERLSAVKSSDLI NKMDLQRAAIILGYRIQGVIAQPVDRVKRPSPESQSNNLWVIVGVVIPVLVVMVIVVILYWKLCRTDKLDFQPDTVANIQQRQKLQIPSV KGFDFAKQHLGQHNKDDILIIHEPAPLPGPLKDHTTPSENGDVPSPKSKIPSKNVRHRGRVSPSDADSTVSEESSERDAGDKTPGAVNDG RSHRAPQSGPPLPSSGNEQHSSASIFEHVDRISRPPEASRRVPSKIQLIAMQPIPAPPVQRPSPADRVAESNKINKEIQTALRHKSEIEH HRNKIRLRAKRRGHYEFPVVDDLSSGDTKERHRVYRRAQMQIDKILDPTASVPSVFIEPRKSSRIKRSPKPRRKHQVNGCPADAEKDRLI TTDSDGTYRRPPGVHNSAYIGCPSDPDLPADVQTPSSVELGRYPALPFPASQYIPPQPSIEEARQTMHSLLDDAFALVAPSSQPASTAGV GPGVPPGLPANSTPSQEERRATQWGSFYSPAQTANNPCSDLIRDQGFRGDGGSTTGLSATPPASLPGSLTNVKALQKSPGPQRERKSSSS SEDRNRMKTLGRRDSSDDWEIPDGQITVGQRIGSGSFGTVYKGKWHGDVAVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGYST KPQLAIVTQWCEGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHEDLTVKIGDFGLATVKSRWSGSHQFE QLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYSNINNRDQIIFMVGRGYLSPDLSKVRSNCPKAMKRLMAECLKKKR >In-frame_KIAA1549_ENST00000422774_chr7_138545885_-_BRAF_ENST00000288602_chr7_140487384_-_2136aa MPGARRRRRGAAMEGKPRAGVALAPGPSGRRPSARCARRRRPGLLLPGLWLLLLARPASCAPDELSPEQHNLSLYSMELVLKKSTGHSAA QVALTETAPGSQHSSPLHVTAPPSATTFDTAFFNQGKQTKSTADPSIFVATYVSVTSKEVAVNDDEMDNFLPDTHWTTPRMVSPIQYITV SPPGLPREALEPMLTPSLPMVSLQDEEVTSGWQNTTRQPAAYAESASHFHTFRSAFRTSEGIVPTPGRNLVLYPTDAYSHLSSRTLPEIV ASLTEGVETTLFLSSRSLMPQPLGDGITIPLPSLGEVSQPPEEVWATSADRYTDVTTVLSQSLEETISPRTYPTVTASHAALAFSRTHSP LLSTPLAFASSASPTDVSSNPFLPSDSSKTSELHSNSALPGPVDNTHILSPVSSFRPYTWCAACTVPSPQQVLATSLMEKDVGSGDGAET LCMTVLEESSISLMSSVVADFSEFEEDPQVFNTLFPSRPIVPLSSRSMEISETSVGISAEVDMSSVTTTQVPPAHGRLSVPASLDPTAGS LSVAETQVTPSSVTTAFFSVITSILLDSSFSVIANKNTPSLAVRDPSVFTPYSLVPSVESSLFSDQERSSFSEHKPRGALDFASSFFSTP PLELSGSISSPSEAPASLSLMPSDLSPFTSQSFSPLVETFTLFDSSDLQSSQLSLPSSTNLEFSQLQPSSELPLNTIMLLPSRSEVSPWS SFPSDSLEFVEASTVSLTDSEAHFTSAFIETTSYLESSLISHESAVTALVPPGSESFDILTAGIQATSPLTTVHTTPILTESSLFSTLTP PDDQISALDGHVSVLASFSKAIPTGTVLITDAYLPSGSSFVSEATPFPLPTELTVVGPSLTPTEVPLNTSTEVSTTSTGAATGGPLDSTL MGDAASQSPPESSAAPPLPSLRPVTAFTLEATVDTPTLATAKPPYVCDITVPDAYLITTVLARRAVQEYIITAIKEVLRIHFNRAVELKV YELFTDFTFLVTSGPFVYTAISVINVLINSKLVRDQTPLILSVKPSFLVPESRFQVQTVLQFVPPSVDTGFCNFTQRIEKGLMTALFEVR KHHQGTYNLTVQILNITISSSRVTPRRGPVNIIFAVKSTQGFLNGSEVSELLRNLSVVEFSFYLGYPVLQIAEPFQYPQLNLSQLLKSSW VRTVLLGVMEKQLQNEVFQAEMERKLAQLLSEVSTRRRMWRRATVAAGNSVVQVVNVSRLEGDDNPVQLIYFVEDQDGERLSAVKSSDLI NKMDLQRAAIILGYRIQGVIAQPVDRVKRPSPESQSNNLWVIVGVVIPVLVVMVIVVILYWKLCRTDKLDFQPDTVANIQQRQKLQIPSV KGFDFAKQHLGQHNKDDILIIHEPAPLPGPLKDHTTPSENGDVPSPKSKIPSKNVRHRGRVSPSDADSTVSEESSERDAGDKTPGAVNDG RSHRAPQSGPPLPSSGNEQHSSASIFEHVDRISRPPEASRRVPSKIQLIAMQPIPAPPVQRPSPADRVAESNKINKEIQTALRHKSEIEH HRNKIRLRAKRRGHYEFPVVDDLSSGDTKERHRVYRRAQMQIDKILDPTASVPSVFIEPRKSSRIKRSPKPRRKHQVNGCPADAEKDRLI TTDSDGTYRRPPGVHNSAYIGCPSDPDLPADVQTPSSVELGRYPALPFPASQYIPPQPSIEEARQTMHSLLDDAFALVAPSSQPASTAGV GPGVPPGLPANSTPSQEERRATQWGSFYSPAQTANNPCSDLIRDQGFRGDGGSTTGLSATPPASLPGSLTNVKALQKSPGPQRERKSSSS SEDRNRMKTLGRRDSSDDWEIPDGQITVGQRIGSGSFGTVYKGKWHGDVAVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGYST KPQLAIVTQWCEGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHEDLTVKIGDFGLATVKSRWSGSHQFE QLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYSNINNRDQIIFMVGRGYLSPDLSKVRSNCPKAMKRLMAECLKKKR |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_KIAA1549_ENST00000242365_chr7_138545885_-_BRAF_ENST00000288602_chr7_140487384_-_6258nt ATGCATTGCACTAACCCAGCTCTGATTTTCTTGATAGATGAGCTCTCTCCGGAACAGCACAACCTTTCTTTATACTCCATGGAGCTCGTG CTGAAGAAAAGCACTGGGCACAGCGCTGCACAAGTGGCCTTAACAGAAACTGCTCCCGGCTCCCAGCACAGCAGTCCTCTCCATGTCACA GCCCCGCCGTCTGCCACTACTTTTGATACAGCCTTTTTTAACCAAGGAAAACAGACCAAAAGTACAGCAGATCCCAGCATCTTTGTGGCA ACTTACGTGTCAGTGACGAGTAAAGAGGTGGCCGTCAATGACGATGAGATGGATAACTTTCTGCCAGATACTCACTGGACCACTCCACGG ATGGTTTCTCCAATACAGTATATCACAGTCAGCCCACCAGGGCTGCCCAGGGAAGCATTAGAACCTATGCTCACTCCATCATTACCCATG GTTTCTTTACAAGATGAAGAAGTGACATCGGGCTGGCAGAACACAACGCGACAACCAGCGGCATATGCTGAGTCCGCCAGTCATTTCCAC ACCTTTCGGTCAGCTTTTCGCACCTCTGAGGGCATCGTTCCAACTCCTGGCAGGAATTTGGTGCTTTATCCTACTGATGCTTACAGTCAT TTATCAAGCAGGACTCTGCCAGAGATTGTGGCTTCCCTAACAGAGGGTGTGGAAACCACCCTTTTTTTAAGCTCCCGGTCTTTAATGCCA CAGCCGTTAGGCGACGGCATTACTATACCGTTGCCCTCCTTGGGGGAGGTCTCACAGCCTCCAGAGGAGGTTTGGGCCACAAGTGCAGAC AGATACACTGATGTGACCACTGTGTTGAGTCAAAGCCTAGAAGAAACCATCTCTCCAAGAACATACCCCACTGTGACTGCATCGCACGCA GCCCTTGCATTCAGCAGGACACATTCTCCATTGCTTTCAACTCCTCTTGCATTTGCGTCCTCTGCTTCACCAACTGATGTTTCATCTAAC CCCTTTCTCCCTAGCGACTCCAGCAAAACATCCGAATTGCATAGCAATTCAGCCCTCCCCGGTCCTGTGGACAACACTCATATCCTGAGC CCGGTGTCCTCATTCAGACCATACACTTGGTGTGCGGCCTGCACTGTGCCTTCACCTCAGCAAGTTCTGGCCACGAGCCTCATGGAGAAA GACGTGGGATCAGGGGATGGTGCCGAGACTCTGTGCATGACCGTGCTGGAAGAAAGCAGCATCTCTCTAATGAGTAGCGTCGTAGCAGAC TTCTCTGAATTTGAGGAAGATCCTCAAGTATTTAATACGCTTTTCCCCTCCAGACCTATCGTCCCACTTTCTTCTAGATCCATGGAAATC TCAGAGACGAGTGTTGGCATTTCTGCCGAGGTGGATATGAGTAGTGTTACAACCACACAGGTTCCCCCTGCCCACGGCCGCCTCTCTGTG CCGGCGTCACTTGATCCTACTGCTGGCTCCTTGTCTGTTGCTGAAACCCAAGTGACGCCATCCAGCGTGACCACTGCATTTTTCTCGGTC ATCACCAGCATTCTCCTTGACTCATCTTTCTCTGTCATAGCAAACAAAAACACACCGTCGCTTGCCGTCAGAGACCCGAGTGTTTTTACG CCTTATAGTCTGGTTCCTTCAGTGGAGTCTTCACTTTTCTCTGACCAAGAACGTTCCAGTTTTTCTGAGCATAAACCCAGAGGTGCTTTG GATTTTGCATCCAGCTTTTTCTCAACACCCCCGCTGGAACTCAGCGGCTCCATCTCTTCGCCTTCGGAAGCACCTGCGTCTCTGTCTCTG ATGCCGAGTGACTTGTCCCCCTTCACATCTCAGTCTTTTTCTCCCTTGGTTGAGACATTTACATTGTTTGACTCTAGTGATCTGCAGTCA TCTCAGCTGTCTCTTCCCAGTTCCACAAATCTTGAGTTTTCGCAGCTCCAGCCAAGTTCCGAGCTGCCTTTAAACACCATCATGTTGCTA CCTAGCCGTTCTGAGGTGTCACCATGGTCAAGCTTCCCTTCTGATTCTCTCGAGTTTGTTGAAGCGTCTACGGTTTCACTGACGGATTCA GAAGCTCATTTTACCTCAGCTTTCATTGAAACTACCTCCTATCTTGAGTCTTCACTCATTTCCCATGAATCCGCAGTCACTGCACTGGTG CCCCCCGGCTCTGAGTCTTTTGACATTTTGACTGCCGGGATTCAAGCAACATCACCATTGACCACTGTCCACACAACGCCCATTTTAACT GAGTCTTCTTTGTTCTCAACTCTGACACCTCCTGACGACCAAATCAGTGCTCTAGACGGTCACGTGTCTGTCCTGGCCTCTTTCTCCAAA GCCATTCCCACTGGTACGGTGTTGATCACTGACGCGTACCTGCCATCAGGATCCTCGTTTGTTTCTGAAGCAACCCCCTTCCCTCTGCCC ACAGAGCTGACCGTCGTGGGCCCATCACTCACACCCACAGAGGTGCCACTGAACACCTCCACGGAAGTGAGCACAACCAGCACCGGTGCT GCCACTGGTGGTCCCCTCGACTCCACCCTGATGGGTGACGCCGCAAGTCAGAGCCCCCCAGAGAGTAGTGCTGCTCCTCCCCTGCCATCC CTGCGTCCCGTGACTGCCTTCACTCTCGAAGCAACAGTCGACACACCAACACTGGCTACTGCCAAGCCGCCATATGTTTGTGATATCACA GTCCCCGATGCCTATCTGATCACAACTGTGCTGGCCAGAAGAGCTGTGCAGGAGTACATCATTACAGCAATCAAAGAAGTACTGAGGATT CACTTCAACCGTGCAGTGGAACTGAAGGTTTACGAACTATTTACTGACTTCACTTTTCTGGTAACATCCGGTCCTTTCGTTTACACGGCA ATATCCGTCATAAATGTGCTTATAAACAGTAAGCTTGTCCGTGACCAGACTCCTTTAATCCTGTCTGTGAAACCTTCTTTCCTTGTGCCA GAGTCCAGGTTCCAAGTTCAAACAGTACTTCAGTTTGTGCCTCCGAGTGTGGATACTGGCTTCTGCAACTTCACCCAGCGCATTGAGAAA GGCCTAATGACAGCTCTCTTTGAAGTGAGAAAACACCACCAGGGAACGTATAACCTCACGGTGCAGATCTTGAATATCACCATCAGTTCC TCAAGGGTGACTCCTCGGCGGGGCCCGGTGAATATCATCTTTGCGGTTAAAAGCACACAGGGATTTTTGAATGGGTCGGAAGTGAGCGAG CTGCTCAGAAACTTGAGTGTGGTGGAGTTCAGTTTCTATCTGGGATACCCAGTGCTGCAGATCGCAGAGCCCTTCCAGTATCCACAGCTC AACTTATCTCAGTTGCTGAAGTCCTCTTGGGTCAGAACAGTTCTCCTGGGCGTCATGGAGAAGCAACTCCAGAATGAAGTGTTTCAAGCC GAGATGGAACGCAAGCTGGCCCAGCTGCTCAGCGAGGTTTCCACCAGAAGGCGGATGTGGAGAAGGGCCACTGTAGCTGCAGGGAACAGT GTGGTGCAGGTGGTAAATGTGTCGAGGCTGGAGGGAGATGACAATCCGGTACAGCTCATCTACTTTGTGGAGGATCAAGATGGAGAAAGA CTCAGTGCAGTCAAGTCTTCGGACCTGATTAACAAAATGGACCTCCAGAGAGCAGCCATCATCTTGGGTTACCGAATTCAAGGTGTCATT GCCCAGCCTGTCGACAGGGTGAAGAGGCCGTCTCCGGAATCCCAGAGCAACAACTTGTGGGTCATTGTTGGCGTGGTCATCCCAGTGCTG GTGGTGATGGTGATTGTTGTCATCCTCTACTGGAAACTATGCCGCACAGACAAGCTAGACTTTCAGCCTGACACTGTGGCCAACATTCAG CAGCGTCAGAAGCTGCAGATCCCTAGTGTGAAGGGCTTCGATTTTGCTAAGCAGCATCTGGGTCAGCACAATAAAGACGACATATTGATT ATTCATGAGCCAGCGCCACTGCCAGGACCTCTGAAGGACCACACCACGCCCTCGGAAAATGGAGACGTGCCAAGCCCCAAGTCAAAGATC CCTTCCAAGAATGTTCGTCACAGAGGAAGAGTTTCTCCCTCAGATGCTGACTCTACGGTCAGTGAAGAGTCCAGCGAGAGGGACGCAGGA GATAAGACGCCGGGAGCCGTCAACGATGGCAGGTCCCACAGAGCTCCGCAGAGCGGGCCACCACTGCCCAGTTCGGGAAATGAGCAGCAC TCATCAGCCTCCATCTTCGAGCACGTGGACAGGATCTCCCGCCCCCCGGAGGCTAGCCGGCGGGTCCCCAGTAAGATCCAGCTTATCGCC ATGCAGCCGATCCCGGCACCTCCCGTCCAGCGCCCCTCCCCAGCCGACCGAGTGGCGGAAAGCAATAAAATCAACAAAGAGATTCAGACC GCGCTGCGGCACAAGTCTGAGATCGAGCACCATCGCAACAAGATCCGCCTGCGCGCCAAGCGCCGCGGGCACTACGAGTTCCCGGTGGTA GACGACCTGTCCTCGGGCGACACTAAGGAGCGACACCGGGTGTACCGCAGGGCACAGATGCAGATCGACAAGATCCTGGACCCCACGGCC AGCGTGCCCTCCGTGTTCATAGAGCCCAGGAAGAGCTCACGGATAAAACGTTCTCCCAAGCCTCGCCGGAAACACCAGGTCAACGGCTGT CCTGCCGACGCTGAGAAGGACCGGCTCATCACCACAGACAGCGATGGCACCTACAGGAGGCCCCCCGGCGTCCACAACTCAGCCTACATC GGATGCCCATCGGATCCTGACCTCCCAGCCGATGTGCAGACACCATCCTCGGTGGAACTGGGGAGGTATCCAGCCCTTCCCTTCCCGGCC TCCCAGTACATCCCACCCCAGCCGTCCATCGAGGAGGCACGCCAGACCATGCACTCCCTCCTGGACGACGCCTTTGCCCTCGTGGCCCCC AGCAGCCAGCCTGCCAGCACCGCAGGTGTAGGCCCCGGAGTCCCACCCGGCCTGCCCGCAAACAGCACCCCTTCCCAGGAAGAGAGGCGA GCCACCCAGTGGGGGTCCTTCTACAGCCCAGCCCAGACGGCCAACAATCCCTGCAGTGACTTGATTAGAGACCAAGGATTTCGTGGTGAT GGAGGATCAACCACAGGTTTGTCTGCTACCCCCCCTGCCTCATTACCTGGCTCACTAACTAACGTGAAAGCCTTACAGAAATCTCCAGGA CCTCAGCGAGAAAGGAAGTCATCTTCATCCTCAGAAGACAGGAATCGAATGAAAACACTTGGTAGACGGGACTCGAGTGATGATTGGGAG ATTCCTGATGGGCAGATTACAGTGGGACAAAGAATTGGATCTGGATCATTTGGAACAGTCTACAAGGGAAAGTGGCATGGTGATGTGGCA GTGAAAATGTTGAATGTGACAGCACCTACACCTCAGCAGTTACAAGCCTTCAAAAATGAAGTAGGAGTACTCAGGAAAACACGACATGTG AATATCCTACTCTTCATGGGCTATTCCACAAAGCCACAACTGGCTATTGTTACCCAGTGGTGTGAGGGCTCCAGCTTGTATCACCATCTC CATATCATTGAGACCAAATTTGAGATGATCAAACTTATAGATATTGCACGACAGACTGCACAGGGCATGGATTACTTACACGCCAAGTCA ATCATCCACAGAGACCTCAAGAGTAATAATATATTTCTTCATGAAGACCTCACAGTAAAAATAGGTGATTTTGGTCTAGCTACAGTGAAA TCTCGATGGAGTGGGTCCCATCAGTTTGAACAGTTGTCTGGATCCATTTTGTGGATGGCACCAGAAGTCATCAGAATGCAAGATAAAAAT CCATACAGCTTTCAGTCAGATGTATATGCATTTGGAATTGTTCTGTATGAATTGATGACTGGACAGTTACCTTATTCAAACATCAACAAC AGGGACCAGATAATTTTTATGGTGGGACGAGGATACCTGTCTCCAGATCTCAGTAAGGTACGGAGTAACTGTCCAAAAGCCATGAAGAGA TTAATGGCAGAGTGCCTCAAAAAGAAAAGAGATGAGAGACCACTCTTTCCCCAAATTCTCGCCTCTATTGAGCTGCTGGCCCGCTCATTG CCAAAAATTCACCGCAGTGCATCAGAACCCTCCTTGAATCGGGCTGGTTTCCAAACAGAGGATTTTAGTCTATATGCTTGTGCTTCTCCA >In-frame_KIAA1549_ENST00000440172_chr7_138545885_-_BRAF_ENST00000288602_chr7_140487384_-_6408nt ATGCCGGGGGCGCGGCGCCGACGCCGAGGCGCGGCCATGGAGGGGAAGCCCCGCGCCGGGGTCGCGCTGGCCCCGGGGCCGAGCGGCCGA CGGCCTTCCGCCCGCTGCGCCCGCCGCCGCCGCCCGGGGCTGCTGCTTCCTGGCCTCTGGCTGCTGCTGCTGGCCCGGCCGGCCTCGTGC GCCCCAGATGAGCTCTCTCCGGAACAGCACAACCTTTCTTTATACTCCATGGAGCTCGTGCTGAAGAAAAGCACTGGGCACAGCGCTGCA CAAGTGGCCTTAACAGAAACTGCTCCCGGCTCCCAGCACAGCAGTCCTCTCCATGTCACAGCCCCGCCGTCTGCCACTACTTTTGATACA GCCTTTTTTAACCAAGGAAAACAGACCAAAAGTACAGCAGATCCCAGCATCTTTGTGGCAACTTACGTGTCAGTGACGAGTAAAGAGGTG GCCGTCAATGACGATGAGATGGATAACTTTCTGCCAGATACTCACTGGACCACTCCACGGATGGTTTCTCCAATACAGTATATCACAGTC AGCCCACCAGGGCTGCCCAGGGAAGCATTAGAACCTATGCTCACTCCATCATTACCCATGGTTTCTTTACAAGATGAAGAAGTGACATCG GGCTGGCAGAACACAACGCGACAACCAGCGGCATATGCTGAGTCCGCCAGTCATTTCCACACCTTTCGGTCAGCTTTTCGCACCTCTGAG GGCATCGTTCCAACTCCTGGCAGGAATTTGGTGCTTTATCCTACTGATGCTTACAGTCATTTATCAAGCAGGACTCTGCCAGAGATTGTG GCTTCCCTAACAGAGGGTGTGGAAACCACCCTTTTTTTAAGCTCCCGGTCTTTAATGCCACAGCCGTTAGGCGACGGCATTACTATACCG TTGCCCTCCTTGGGGGAGGTCTCACAGCCTCCAGAGGAGGTTTGGGCCACAAGTGCAGACAGATACACTGATGTGACCACTGTGTTGAGT CAAAGCCTAGAAGAAACCATCTCTCCAAGAACATACCCCACTGTGACTGCATCGCACGCAGCCCTTGCATTCAGCAGGACACATTCTCCA TTGCTTTCAACTCCTCTTGCATTTGCGTCCTCTGCTTCACCAACTGATGTTTCATCTAACCCCTTTCTCCCTAGCGACTCCAGCAAAACA TCCGAATTGCATAGCAATTCAGCCCTCCCCGGTCCTGTGGACAACACTCATATCCTGAGCCCGGTGTCCTCATTCAGACCATACACTTGG TGTGCGGCCTGCACTGTGCCTTCACCTCAGCAAGTTCTGGCCACGAGCCTCATGGAGAAAGACGTGGGATCAGGGGATGGTGCCGAGACT CTGTGCATGACCGTGCTGGAAGAAAGCAGCATCTCTCTAATGAGTAGCGTCGTAGCAGACTTCTCTGAATTTGAGGAAGATCCTCAAGTA TTTAATACGCTTTTCCCCTCCAGACCTATCGTCCCACTTTCTTCTAGATCCATGGAAATCTCAGAGACGAGTGTTGGCATTTCTGCCGAG GTGGATATGAGTAGTGTTACAACCACACAGGTTCCCCCTGCCCACGGCCGCCTCTCTGTGCCGGCGTCACTTGATCCTACTGCTGGCTCC TTGTCTGTTGCTGAAACCCAAGTGACGCCATCCAGCGTGACCACTGCATTTTTCTCGGTCATCACCAGCATTCTCCTTGACTCATCTTTC TCTGTCATAGCAAACAAAAACACACCGTCGCTTGCCGTCAGAGACCCGAGTGTTTTTACGCCTTATAGTCTGGTTCCTTCAGTGGAGTCT TCACTTTTCTCTGACCAAGAACGTTCCAGTTTTTCTGAGCATAAACCCAGAGGTGCTTTGGATTTTGCATCCAGCTTTTTCTCAACACCC CCGCTGGAACTCAGCGGCTCCATCTCTTCGCCTTCGGAAGCACCTGCGTCTCTGTCTCTGATGCCGAGTGACTTGTCCCCCTTCACATCT CAGTCTTTTTCTCCCTTGGTTGAGACATTTACATTGTTTGACTCTAGTGATCTGCAGTCATCTCAGCTGTCTCTTCCCAGTTCCACAAAT CTTGAGTTTTCGCAGCTCCAGCCAAGTTCCGAGCTGCCTTTAAACACCATCATGTTGCTACCTAGCCGTTCTGAGGTGTCACCATGGTCA AGCTTCCCTTCTGATTCTCTCGAGTTTGTTGAAGCGTCTACGGTTTCACTGACGGATTCAGAAGCTCATTTTACCTCAGCTTTCATTGAA ACTACCTCCTATCTTGAGTCTTCACTCATTTCCCATGAATCCGCAGTCACTGCACTGGTGCCCCCCGGCTCTGAGTCTTTTGACATTTTG ACTGCCGGGATTCAAGCAACATCACCATTGACCACTGTCCACACAACGCCCATTTTAACTGAGTCTTCTTTGTTCTCAACTCTGACACCT CCTGACGACCAAATCAGTGCTCTAGACGGTCACGTGTCTGTCCTGGCCTCTTTCTCCAAAGCCATTCCCACTGGTACGGTGTTGATCACT GACGCGTACCTGCCATCAGGATCCTCGTTTGTTTCTGAAGCAACCCCCTTCCCTCTGCCCACAGAGCTGACCGTCGTGGGCCCATCACTC ACACCCACAGAGGTGCCACTGAACACCTCCACGGAAGTGAGCACAACCAGCACCGGTGCTGCCACTGGTGGTCCCCTCGACTCCACCCTG ATGGGTGACGCCGCAAGTCAGAGCCCCCCAGAGAGTAGTGCTGCTCCTCCCCTGCCATCCCTGCGTCCCGTGACTGCCTTCACTCTCGAA GCAACAGTCGACACACCAACACTGGCTACTGCCAAGCCGCCATATGTTTGTGATATCACAGTCCCCGATGCCTATCTGATCACAACTGTG CTGGCCAGAAGAGCTGTGCAGGAGTACATCATTACAGCAATCAAAGAAGTACTGAGGATTCACTTCAACCGTGCAGTGGAACTGAAGGTT TACGAACTATTTACTGACTTCACTTTTCTGGTAACATCCGGTCCTTTCGTTTACACGGCAATATCCGTCATAAATGTGCTTATAAACAGT AAGCTTGTCCGTGACCAGACTCCTTTAATCCTGTCTGTGAAACCTTCTTTCCTTGTGCCAGAGTCCAGGTTCCAAGTTCAAACAGTACTT CAGTTTGTGCCTCCGAGTGTGGATACTGGCTTCTGCAACTTCACCCAGCGCATTGAGAAAGGCCTAATGACAGCTCTCTTTGAAGTGAGA AAACACCACCAGGGAACGTATAACCTCACGGTGCAGATCTTGAATATCACCATCAGTTCCTCAAGGGTGACTCCTCGGCGGGGCCCGGTG AATATCATCTTTGCGGTTAAAAGCACACAGGGATTTTTGAATGGGTCGGAAGTGAGCGAGCTGCTCAGAAACTTGAGTGTGGTGGAGTTC AGTTTCTATCTGGGATACCCAGTGCTGCAGATCGCAGAGCCCTTCCAGTATCCACAGCTCAACTTATCTCAGTTGCTGAAGTCCTCTTGG GTCAGAACAGTTCTCCTGGGCGTCATGGAGAAGCAACTCCAGAATGAAGTGTTTCAAGCCGAGATGGAACGCAAGCTGGCCCAGCTGCTC AGCGAGGTTTCCACCAGAAGGCGGATGTGGAGAAGGGCCACTGTAGCTGCAGGGAACAGTGTGGTGCAGGTGGTAAATGTGTCGAGGCTG GAGGGAGATGACAATCCGGTACAGCTCATCTACTTTGTGGAGGATCAAGATGGAGAAAGACTCAGTGCAGTCAAGTCTTCGGACCTGATT AACAAAATGGACCTCCAGAGAGCAGCCATCATCTTGGGTTACCGAATTCAAGGTGTCATTGCCCAGCCTGTCGACAGGGTGAAGAGGCCG TCTCCGGAATCCCAGAGCAACAACTTGTGGGTCATTGTTGGCGTGGTCATCCCAGTGCTGGTGGTGATGGTGATTGTTGTCATCCTCTAC TGGAAACTATGCCGCACAGACAAGCTAGACTTTCAGCCTGACACTGTGGCCAACATTCAGCAGCGTCAGAAGCTGCAGATCCCTAGTGTG AAGGGCTTCGATTTTGCTAAGCAGCATCTGGGTCAGCACAATAAAGACGACATATTGATTATTCATGAGCCAGCGCCACTGCCAGGACCT CTGAAGGACCACACCACGCCCTCGGAAAATGGAGACGTGCCAAGCCCCAAGTCAAAGATCCCTTCCAAGAATGTTCGTCACAGAGGAAGA GTTTCTCCCTCAGATGCTGACTCTACGGTCAGTGAAGAGTCCAGCGAGAGGGACGCAGGAGATAAGACGCCGGGAGCCGTCAACGATGGC AGGTCCCACAGAGCTCCGCAGAGCGGGCCACCACTGCCCAGTTCGGGAAATGAGCAGCACTCATCAGCCTCCATCTTCGAGCACGTGGAC AGGATCTCCCGCCCCCCGGAGGCTAGCCGGCGGGTCCCCAGTAAGATCCAGCTTATCGCCATGCAGCCGATCCCGGCACCTCCCGTCCAG CGCCCCTCCCCAGCCGACCGAGTGGCGGAAAGCAATAAAATCAACAAAGAGATTCAGACCGCGCTGCGGCACAAGTCTGAGATCGAGCAC CATCGCAACAAGATCCGCCTGCGCGCCAAGCGCCGCGGGCACTACGAGTTCCCGGTGGTAGACGACCTGTCCTCGGGCGACACTAAGGAG CGACACCGGGTGTACCGCAGGGCACAGATGCAGATCGACAAGATCCTGGACCCCACGGCCAGCGTGCCCTCCGTGTTCATAGAGCCCAGG AAGAGCTCACGGATAAAACGTTCTCCCAAGCCTCGCCGGAAACACCAGGTCAACGGCTGTCCTGCCGACGCTGAGAAGGACCGGCTCATC ACCACAGACAGCGATGGCACCTACAGGAGGCCCCCCGGCGTCCACAACTCAGCCTACATCGGATGCCCATCGGATCCTGACCTCCCAGCC GATGTGCAGACACCATCCTCGGTGGAACTGGGGAGGTATCCAGCCCTTCCCTTCCCGGCCTCCCAGTACATCCCACCCCAGCCGTCCATC GAGGAGGCACGCCAGACCATGCACTCCCTCCTGGACGACGCCTTTGCCCTCGTGGCCCCCAGCAGCCAGCCTGCCAGCACCGCAGGTGTA GGCCCCGGAGTCCCACCCGGCCTGCCCGCAAACAGCACCCCTTCCCAGGAAGAGAGGCGAGCCACCCAGTGGGGGTCCTTCTACAGCCCA GCCCAGACGGCCAACAATCCCTGCAGTGACTTGATTAGAGACCAAGGATTTCGTGGTGATGGAGGATCAACCACAGGTTTGTCTGCTACC CCCCCTGCCTCATTACCTGGCTCACTAACTAACGTGAAAGCCTTACAGAAATCTCCAGGACCTCAGCGAGAAAGGAAGTCATCTTCATCC TCAGAAGACAGGAATCGAATGAAAACACTTGGTAGACGGGACTCGAGTGATGATTGGGAGATTCCTGATGGGCAGATTACAGTGGGACAA AGAATTGGATCTGGATCATTTGGAACAGTCTACAAGGGAAAGTGGCATGGTGATGTGGCAGTGAAAATGTTGAATGTGACAGCACCTACA CCTCAGCAGTTACAAGCCTTCAAAAATGAAGTAGGAGTACTCAGGAAAACACGACATGTGAATATCCTACTCTTCATGGGCTATTCCACA AAGCCACAACTGGCTATTGTTACCCAGTGGTGTGAGGGCTCCAGCTTGTATCACCATCTCCATATCATTGAGACCAAATTTGAGATGATC AAACTTATAGATATTGCACGACAGACTGCACAGGGCATGGATTACTTACACGCCAAGTCAATCATCCACAGAGACCTCAAGAGTAATAAT ATATTTCTTCATGAAGACCTCACAGTAAAAATAGGTGATTTTGGTCTAGCTACAGTGAAATCTCGATGGAGTGGGTCCCATCAGTTTGAA CAGTTGTCTGGATCCATTTTGTGGATGGCACCAGAAGTCATCAGAATGCAAGATAAAAATCCATACAGCTTTCAGTCAGATGTATATGCA TTTGGAATTGTTCTGTATGAATTGATGACTGGACAGTTACCTTATTCAAACATCAACAACAGGGACCAGATAATTTTTATGGTGGGACGA GGATACCTGTCTCCAGATCTCAGTAAGGTACGGAGTAACTGTCCAAAAGCCATGAAGAGATTAATGGCAGAGTGCCTCAAAAAGAAAAGA GATGAGAGACCACTCTTTCCCCAAATTCTCGCCTCTATTGAGCTGCTGGCCCGCTCATTGCCAAAAATTCACCGCAGTGCATCAGAACCC TCCTTGAATCGGGCTGGTTTCCAAACAGAGGATTTTAGTCTATATGCTTGTGCTTCTCCAAAAACACCCATCCAGGCAGGGGGATATGGT >In-frame_KIAA1549_ENST00000422774_chr7_138545885_-_BRAF_ENST00000288602_chr7_140487384_-_6408nt ATGCCGGGGGCGCGGCGCCGACGCCGAGGCGCGGCCATGGAGGGGAAGCCCCGCGCCGGGGTCGCGCTGGCCCCGGGGCCGAGCGGCCGA CGGCCTTCCGCCCGCTGCGCCCGCCGCCGCCGCCCGGGGCTGCTGCTTCCTGGCCTCTGGCTGCTGCTGCTGGCCCGGCCGGCCTCGTGC GCCCCAGATGAGCTCTCTCCGGAACAGCACAACCTTTCTTTATACTCCATGGAGCTCGTGCTGAAGAAAAGCACTGGGCACAGCGCTGCA CAAGTGGCCTTAACAGAAACTGCTCCCGGCTCCCAGCACAGCAGTCCTCTCCATGTCACAGCCCCGCCGTCTGCCACTACTTTTGATACA GCCTTTTTTAACCAAGGAAAACAGACCAAAAGTACAGCAGATCCCAGCATCTTTGTGGCAACTTACGTGTCAGTGACGAGTAAAGAGGTG GCCGTCAATGACGATGAGATGGATAACTTTCTGCCAGATACTCACTGGACCACTCCACGGATGGTTTCTCCAATACAGTATATCACAGTC AGCCCACCAGGGCTGCCCAGGGAAGCATTAGAACCTATGCTCACTCCATCATTACCCATGGTTTCTTTACAAGATGAAGAAGTGACATCG GGCTGGCAGAACACAACGCGACAACCAGCGGCATATGCTGAGTCCGCCAGTCATTTCCACACCTTTCGGTCAGCTTTTCGCACCTCTGAG GGCATCGTTCCAACTCCTGGCAGGAATTTGGTGCTTTATCCTACTGATGCTTACAGTCATTTATCAAGCAGGACTCTGCCAGAGATTGTG GCTTCCCTAACAGAGGGTGTGGAAACCACCCTTTTTTTAAGCTCCCGGTCTTTAATGCCACAGCCGTTAGGCGACGGCATTACTATACCG TTGCCCTCCTTGGGGGAGGTCTCACAGCCTCCAGAGGAGGTTTGGGCCACAAGTGCAGACAGATACACTGATGTGACCACTGTGTTGAGT CAAAGCCTAGAAGAAACCATCTCTCCAAGAACATACCCCACTGTGACTGCATCGCACGCAGCCCTTGCATTCAGCAGGACACATTCTCCA TTGCTTTCAACTCCTCTTGCATTTGCGTCCTCTGCTTCACCAACTGATGTTTCATCTAACCCCTTTCTCCCTAGCGACTCCAGCAAAACA TCCGAATTGCATAGCAATTCAGCCCTCCCCGGTCCTGTGGACAACACTCATATCCTGAGCCCGGTGTCCTCATTCAGACCATACACTTGG TGTGCGGCCTGCACTGTGCCTTCACCTCAGCAAGTTCTGGCCACGAGCCTCATGGAGAAAGACGTGGGATCAGGGGATGGTGCCGAGACT CTGTGCATGACCGTGCTGGAAGAAAGCAGCATCTCTCTAATGAGTAGCGTCGTAGCAGACTTCTCTGAATTTGAGGAAGATCCTCAAGTA TTTAATACGCTTTTCCCCTCCAGACCTATCGTCCCACTTTCTTCTAGATCCATGGAAATCTCAGAGACGAGTGTTGGCATTTCTGCCGAG GTGGATATGAGTAGTGTTACAACCACACAGGTTCCCCCTGCCCACGGCCGCCTCTCTGTGCCGGCGTCACTTGATCCTACTGCTGGCTCC TTGTCTGTTGCTGAAACCCAAGTGACGCCATCCAGCGTGACCACTGCATTTTTCTCGGTCATCACCAGCATTCTCCTTGACTCATCTTTC TCTGTCATAGCAAACAAAAACACACCGTCGCTTGCCGTCAGAGACCCGAGTGTTTTTACGCCTTATAGTCTGGTTCCTTCAGTGGAGTCT TCACTTTTCTCTGACCAAGAACGTTCCAGTTTTTCTGAGCATAAACCCAGAGGTGCTTTGGATTTTGCATCCAGCTTTTTCTCAACACCC CCGCTGGAACTCAGCGGCTCCATCTCTTCGCCTTCGGAAGCACCTGCGTCTCTGTCTCTGATGCCGAGTGACTTGTCCCCCTTCACATCT CAGTCTTTTTCTCCCTTGGTTGAGACATTTACATTGTTTGACTCTAGTGATCTGCAGTCATCTCAGCTGTCTCTTCCCAGTTCCACAAAT CTTGAGTTTTCGCAGCTCCAGCCAAGTTCCGAGCTGCCTTTAAACACCATCATGTTGCTACCTAGCCGTTCTGAGGTGTCACCATGGTCA AGCTTCCCTTCTGATTCTCTCGAGTTTGTTGAAGCGTCTACGGTTTCACTGACGGATTCAGAAGCTCATTTTACCTCAGCTTTCATTGAA ACTACCTCCTATCTTGAGTCTTCACTCATTTCCCATGAATCCGCAGTCACTGCACTGGTGCCCCCCGGCTCTGAGTCTTTTGACATTTTG ACTGCCGGGATTCAAGCAACATCACCATTGACCACTGTCCACACAACGCCCATTTTAACTGAGTCTTCTTTGTTCTCAACTCTGACACCT CCTGACGACCAAATCAGTGCTCTAGACGGTCACGTGTCTGTCCTGGCCTCTTTCTCCAAAGCCATTCCCACTGGTACGGTGTTGATCACT GACGCGTACCTGCCATCAGGATCCTCGTTTGTTTCTGAAGCAACCCCCTTCCCTCTGCCCACAGAGCTGACCGTCGTGGGCCCATCACTC ACACCCACAGAGGTGCCACTGAACACCTCCACGGAAGTGAGCACAACCAGCACCGGTGCTGCCACTGGTGGTCCCCTCGACTCCACCCTG ATGGGTGACGCCGCAAGTCAGAGCCCCCCAGAGAGTAGTGCTGCTCCTCCCCTGCCATCCCTGCGTCCCGTGACTGCCTTCACTCTCGAA GCAACAGTCGACACACCAACACTGGCTACTGCCAAGCCGCCATATGTTTGTGATATCACAGTCCCCGATGCCTATCTGATCACAACTGTG CTGGCCAGAAGAGCTGTGCAGGAGTACATCATTACAGCAATCAAAGAAGTACTGAGGATTCACTTCAACCGTGCAGTGGAACTGAAGGTT TACGAACTATTTACTGACTTCACTTTTCTGGTAACATCCGGTCCTTTCGTTTACACGGCAATATCCGTCATAAATGTGCTTATAAACAGT AAGCTTGTCCGTGACCAGACTCCTTTAATCCTGTCTGTGAAACCTTCTTTCCTTGTGCCAGAGTCCAGGTTCCAAGTTCAAACAGTACTT CAGTTTGTGCCTCCGAGTGTGGATACTGGCTTCTGCAACTTCACCCAGCGCATTGAGAAAGGCCTAATGACAGCTCTCTTTGAAGTGAGA AAACACCACCAGGGAACGTATAACCTCACGGTGCAGATCTTGAATATCACCATCAGTTCCTCAAGGGTGACTCCTCGGCGGGGCCCGGTG AATATCATCTTTGCGGTTAAAAGCACACAGGGATTTTTGAATGGGTCGGAAGTGAGCGAGCTGCTCAGAAACTTGAGTGTGGTGGAGTTC AGTTTCTATCTGGGATACCCAGTGCTGCAGATCGCAGAGCCCTTCCAGTATCCACAGCTCAACTTATCTCAGTTGCTGAAGTCCTCTTGG GTCAGAACAGTTCTCCTGGGCGTCATGGAGAAGCAACTCCAGAATGAAGTGTTTCAAGCCGAGATGGAACGCAAGCTGGCCCAGCTGCTC AGCGAGGTTTCCACCAGAAGGCGGATGTGGAGAAGGGCCACTGTAGCTGCAGGGAACAGTGTGGTGCAGGTGGTAAATGTGTCGAGGCTG GAGGGAGATGACAATCCGGTACAGCTCATCTACTTTGTGGAGGATCAAGATGGAGAAAGACTCAGTGCAGTCAAGTCTTCGGACCTGATT AACAAAATGGACCTCCAGAGAGCAGCCATCATCTTGGGTTACCGAATTCAAGGTGTCATTGCCCAGCCTGTCGACAGGGTGAAGAGGCCG TCTCCGGAATCCCAGAGCAACAACTTGTGGGTCATTGTTGGCGTGGTCATCCCAGTGCTGGTGGTGATGGTGATTGTTGTCATCCTCTAC TGGAAACTATGCCGCACAGACAAGCTAGACTTTCAGCCTGACACTGTGGCCAACATTCAGCAGCGTCAGAAGCTGCAGATCCCTAGTGTG AAGGGCTTCGATTTTGCTAAGCAGCATCTGGGTCAGCACAATAAAGACGACATATTGATTATTCATGAGCCAGCGCCACTGCCAGGACCT CTGAAGGACCACACCACGCCCTCGGAAAATGGAGACGTGCCAAGCCCCAAGTCAAAGATCCCTTCCAAGAATGTTCGTCACAGAGGAAGA GTTTCTCCCTCAGATGCTGACTCTACGGTCAGTGAAGAGTCCAGCGAGAGGGACGCAGGAGATAAGACGCCGGGAGCCGTCAACGATGGC AGGTCCCACAGAGCTCCGCAGAGCGGGCCACCACTGCCCAGTTCGGGAAATGAGCAGCACTCATCAGCCTCCATCTTCGAGCACGTGGAC AGGATCTCCCGCCCCCCGGAGGCTAGCCGGCGGGTCCCCAGTAAGATCCAGCTTATCGCCATGCAGCCGATCCCGGCACCTCCCGTCCAG CGCCCCTCCCCAGCCGACCGAGTGGCGGAAAGCAATAAAATCAACAAAGAGATTCAGACCGCGCTGCGGCACAAGTCTGAGATCGAGCAC CATCGCAACAAGATCCGCCTGCGCGCCAAGCGCCGCGGGCACTACGAGTTCCCGGTGGTAGACGACCTGTCCTCGGGCGACACTAAGGAG CGACACCGGGTGTACCGCAGGGCACAGATGCAGATCGACAAGATCCTGGACCCCACGGCCAGCGTGCCCTCCGTGTTCATAGAGCCCAGG AAGAGCTCACGGATAAAACGTTCTCCCAAGCCTCGCCGGAAACACCAGGTCAACGGCTGTCCTGCCGACGCTGAGAAGGACCGGCTCATC ACCACAGACAGCGATGGCACCTACAGGAGGCCCCCCGGCGTCCACAACTCAGCCTACATCGGATGCCCATCGGATCCTGACCTCCCAGCC GATGTGCAGACACCATCCTCGGTGGAACTGGGGAGGTATCCAGCCCTTCCCTTCCCGGCCTCCCAGTACATCCCACCCCAGCCGTCCATC GAGGAGGCACGCCAGACCATGCACTCCCTCCTGGACGACGCCTTTGCCCTCGTGGCCCCCAGCAGCCAGCCTGCCAGCACCGCAGGTGTA GGCCCCGGAGTCCCACCCGGCCTGCCCGCAAACAGCACCCCTTCCCAGGAAGAGAGGCGAGCCACCCAGTGGGGGTCCTTCTACAGCCCA GCCCAGACGGCCAACAATCCCTGCAGTGACTTGATTAGAGACCAAGGATTTCGTGGTGATGGAGGATCAACCACAGGTTTGTCTGCTACC CCCCCTGCCTCATTACCTGGCTCACTAACTAACGTGAAAGCCTTACAGAAATCTCCAGGACCTCAGCGAGAAAGGAAGTCATCTTCATCC TCAGAAGACAGGAATCGAATGAAAACACTTGGTAGACGGGACTCGAGTGATGATTGGGAGATTCCTGATGGGCAGATTACAGTGGGACAA AGAATTGGATCTGGATCATTTGGAACAGTCTACAAGGGAAAGTGGCATGGTGATGTGGCAGTGAAAATGTTGAATGTGACAGCACCTACA CCTCAGCAGTTACAAGCCTTCAAAAATGAAGTAGGAGTACTCAGGAAAACACGACATGTGAATATCCTACTCTTCATGGGCTATTCCACA AAGCCACAACTGGCTATTGTTACCCAGTGGTGTGAGGGCTCCAGCTTGTATCACCATCTCCATATCATTGAGACCAAATTTGAGATGATC AAACTTATAGATATTGCACGACAGACTGCACAGGGCATGGATTACTTACACGCCAAGTCAATCATCCACAGAGACCTCAAGAGTAATAAT ATATTTCTTCATGAAGACCTCACAGTAAAAATAGGTGATTTTGGTCTAGCTACAGTGAAATCTCGATGGAGTGGGTCCCATCAGTTTGAA CAGTTGTCTGGATCCATTTTGTGGATGGCACCAGAAGTCATCAGAATGCAAGATAAAAATCCATACAGCTTTCAGTCAGATGTATATGCA TTTGGAATTGTTCTGTATGAATTGATGACTGGACAGTTACCTTATTCAAACATCAACAACAGGGACCAGATAATTTTTATGGTGGGACGA GGATACCTGTCTCCAGATCTCAGTAAGGTACGGAGTAACTGTCCAAAAGCCATGAAGAGATTAATGGCAGAGTGCCTCAAAAAGAAAAGA GATGAGAGACCACTCTTTCCCCAAATTCTCGCCTCTATTGAGCTGCTGGCCCGCTCATTGCCAAAAATTCACCGCAGTGCATCAGAACCC TCCTTGAATCGGGCTGGTTTCCAAACAGAGGATTTTAGTCTATATGCTTGTGCTTCTCCAAAAACACCCATCCAGGCAGGGGGATATGGT |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_KIAA1549_ENST00000242365_chr7_138545885_-_BRAF_ENST00000288602_chr7_140487384_-_6376nt ATGCATTGCACTAACCCAGCTCTGATTTTCTTGATAGATGAGCTCTCTCCGGAACAGCACAACCTTTCTTTATACTCCATGGAGCTCGTG CTGAAGAAAAGCACTGGGCACAGCGCTGCACAAGTGGCCTTAACAGAAACTGCTCCCGGCTCCCAGCACAGCAGTCCTCTCCATGTCACA GCCCCGCCGTCTGCCACTACTTTTGATACAGCCTTTTTTAACCAAGGAAAACAGACCAAAAGTACAGCAGATCCCAGCATCTTTGTGGCA ACTTACGTGTCAGTGACGAGTAAAGAGGTGGCCGTCAATGACGATGAGATGGATAACTTTCTGCCAGATACTCACTGGACCACTCCACGG ATGGTTTCTCCAATACAGTATATCACAGTCAGCCCACCAGGGCTGCCCAGGGAAGCATTAGAACCTATGCTCACTCCATCATTACCCATG GTTTCTTTACAAGATGAAGAAGTGACATCGGGCTGGCAGAACACAACGCGACAACCAGCGGCATATGCTGAGTCCGCCAGTCATTTCCAC ACCTTTCGGTCAGCTTTTCGCACCTCTGAGGGCATCGTTCCAACTCCTGGCAGGAATTTGGTGCTTTATCCTACTGATGCTTACAGTCAT TTATCAAGCAGGACTCTGCCAGAGATTGTGGCTTCCCTAACAGAGGGTGTGGAAACCACCCTTTTTTTAAGCTCCCGGTCTTTAATGCCA CAGCCGTTAGGCGACGGCATTACTATACCGTTGCCCTCCTTGGGGGAGGTCTCACAGCCTCCAGAGGAGGTTTGGGCCACAAGTGCAGAC AGATACACTGATGTGACCACTGTGTTGAGTCAAAGCCTAGAAGAAACCATCTCTCCAAGAACATACCCCACTGTGACTGCATCGCACGCA GCCCTTGCATTCAGCAGGACACATTCTCCATTGCTTTCAACTCCTCTTGCATTTGCGTCCTCTGCTTCACCAACTGATGTTTCATCTAAC CCCTTTCTCCCTAGCGACTCCAGCAAAACATCCGAATTGCATAGCAATTCAGCCCTCCCCGGTCCTGTGGACAACACTCATATCCTGAGC CCGGTGTCCTCATTCAGACCATACACTTGGTGTGCGGCCTGCACTGTGCCTTCACCTCAGCAAGTTCTGGCCACGAGCCTCATGGAGAAA GACGTGGGATCAGGGGATGGTGCCGAGACTCTGTGCATGACCGTGCTGGAAGAAAGCAGCATCTCTCTAATGAGTAGCGTCGTAGCAGAC TTCTCTGAATTTGAGGAAGATCCTCAAGTATTTAATACGCTTTTCCCCTCCAGACCTATCGTCCCACTTTCTTCTAGATCCATGGAAATC TCAGAGACGAGTGTTGGCATTTCTGCCGAGGTGGATATGAGTAGTGTTACAACCACACAGGTTCCCCCTGCCCACGGCCGCCTCTCTGTG CCGGCGTCACTTGATCCTACTGCTGGCTCCTTGTCTGTTGCTGAAACCCAAGTGACGCCATCCAGCGTGACCACTGCATTTTTCTCGGTC ATCACCAGCATTCTCCTTGACTCATCTTTCTCTGTCATAGCAAACAAAAACACACCGTCGCTTGCCGTCAGAGACCCGAGTGTTTTTACG CCTTATAGTCTGGTTCCTTCAGTGGAGTCTTCACTTTTCTCTGACCAAGAACGTTCCAGTTTTTCTGAGCATAAACCCAGAGGTGCTTTG GATTTTGCATCCAGCTTTTTCTCAACACCCCCGCTGGAACTCAGCGGCTCCATCTCTTCGCCTTCGGAAGCACCTGCGTCTCTGTCTCTG ATGCCGAGTGACTTGTCCCCCTTCACATCTCAGTCTTTTTCTCCCTTGGTTGAGACATTTACATTGTTTGACTCTAGTGATCTGCAGTCA TCTCAGCTGTCTCTTCCCAGTTCCACAAATCTTGAGTTTTCGCAGCTCCAGCCAAGTTCCGAGCTGCCTTTAAACACCATCATGTTGCTA CCTAGCCGTTCTGAGGTGTCACCATGGTCAAGCTTCCCTTCTGATTCTCTCGAGTTTGTTGAAGCGTCTACGGTTTCACTGACGGATTCA GAAGCTCATTTTACCTCAGCTTTCATTGAAACTACCTCCTATCTTGAGTCTTCACTCATTTCCCATGAATCCGCAGTCACTGCACTGGTG CCCCCCGGCTCTGAGTCTTTTGACATTTTGACTGCCGGGATTCAAGCAACATCACCATTGACCACTGTCCACACAACGCCCATTTTAACT GAGTCTTCTTTGTTCTCAACTCTGACACCTCCTGACGACCAAATCAGTGCTCTAGACGGTCACGTGTCTGTCCTGGCCTCTTTCTCCAAA GCCATTCCCACTGGTACGGTGTTGATCACTGACGCGTACCTGCCATCAGGATCCTCGTTTGTTTCTGAAGCAACCCCCTTCCCTCTGCCC ACAGAGCTGACCGTCGTGGGCCCATCACTCACACCCACAGAGGTGCCACTGAACACCTCCACGGAAGTGAGCACAACCAGCACCGGTGCT GCCACTGGTGGTCCCCTCGACTCCACCCTGATGGGTGACGCCGCAAGTCAGAGCCCCCCAGAGAGTAGTGCTGCTCCTCCCCTGCCATCC CTGCGTCCCGTGACTGCCTTCACTCTCGAAGCAACAGTCGACACACCAACACTGGCTACTGCCAAGCCGCCATATGTTTGTGATATCACA GTCCCCGATGCCTATCTGATCACAACTGTGCTGGCCAGAAGAGCTGTGCAGGAGTACATCATTACAGCAATCAAAGAAGTACTGAGGATT CACTTCAACCGTGCAGTGGAACTGAAGGTTTACGAACTATTTACTGACTTCACTTTTCTGGTAACATCCGGTCCTTTCGTTTACACGGCA ATATCCGTCATAAATGTGCTTATAAACAGTAAGCTTGTCCGTGACCAGACTCCTTTAATCCTGTCTGTGAAACCTTCTTTCCTTGTGCCA GAGTCCAGGTTCCAAGTTCAAACAGTACTTCAGTTTGTGCCTCCGAGTGTGGATACTGGCTTCTGCAACTTCACCCAGCGCATTGAGAAA GGCCTAATGACAGCTCTCTTTGAAGTGAGAAAACACCACCAGGGAACGTATAACCTCACGGTGCAGATCTTGAATATCACCATCAGTTCC TCAAGGGTGACTCCTCGGCGGGGCCCGGTGAATATCATCTTTGCGGTTAAAAGCACACAGGGATTTTTGAATGGGTCGGAAGTGAGCGAG CTGCTCAGAAACTTGAGTGTGGTGGAGTTCAGTTTCTATCTGGGATACCCAGTGCTGCAGATCGCAGAGCCCTTCCAGTATCCACAGCTC AACTTATCTCAGTTGCTGAAGTCCTCTTGGGTCAGAACAGTTCTCCTGGGCGTCATGGAGAAGCAACTCCAGAATGAAGTGTTTCAAGCC GAGATGGAACGCAAGCTGGCCCAGCTGCTCAGCGAGGTTTCCACCAGAAGGCGGATGTGGAGAAGGGCCACTGTAGCTGCAGGGAACAGT GTGGTGCAGGTGGTAAATGTGTCGAGGCTGGAGGGAGATGACAATCCGGTACAGCTCATCTACTTTGTGGAGGATCAAGATGGAGAAAGA CTCAGTGCAGTCAAGTCTTCGGACCTGATTAACAAAATGGACCTCCAGAGAGCAGCCATCATCTTGGGTTACCGAATTCAAGGTGTCATT GCCCAGCCTGTCGACAGGGTGAAGAGGCCGTCTCCGGAATCCCAGAGCAACAACTTGTGGGTCATTGTTGGCGTGGTCATCCCAGTGCTG GTGGTGATGGTGATTGTTGTCATCCTCTACTGGAAACTATGCCGCACAGACAAGCTAGACTTTCAGCCTGACACTGTGGCCAACATTCAG CAGCGTCAGAAGCTGCAGATCCCTAGTGTGAAGGGCTTCGATTTTGCTAAGCAGCATCTGGGTCAGCACAATAAAGACGACATATTGATT ATTCATGAGCCAGCGCCACTGCCAGGACCTCTGAAGGACCACACCACGCCCTCGGAAAATGGAGACGTGCCAAGCCCCAAGTCAAAGATC CCTTCCAAGAATGTTCGTCACAGAGGAAGAGTTTCTCCCTCAGATGCTGACTCTACGGTCAGTGAAGAGTCCAGCGAGAGGGACGCAGGA GATAAGACGCCGGGAGCCGTCAACGATGGCAGGTCCCACAGAGCTCCGCAGAGCGGGCCACCACTGCCCAGTTCGGGAAATGAGCAGCAC TCATCAGCCTCCATCTTCGAGCACGTGGACAGGATCTCCCGCCCCCCGGAGGCTAGCCGGCGGGTCCCCAGTAAGATCCAGCTTATCGCC ATGCAGCCGATCCCGGCACCTCCCGTCCAGCGCCCCTCCCCAGCCGACCGAGTGGCGGAAAGCAATAAAATCAACAAAGAGATTCAGACC GCGCTGCGGCACAAGTCTGAGATCGAGCACCATCGCAACAAGATCCGCCTGCGCGCCAAGCGCCGCGGGCACTACGAGTTCCCGGTGGTA GACGACCTGTCCTCGGGCGACACTAAGGAGCGACACCGGGTGTACCGCAGGGCACAGATGCAGATCGACAAGATCCTGGACCCCACGGCC AGCGTGCCCTCCGTGTTCATAGAGCCCAGGAAGAGCTCACGGATAAAACGTTCTCCCAAGCCTCGCCGGAAACACCAGGTCAACGGCTGT CCTGCCGACGCTGAGAAGGACCGGCTCATCACCACAGACAGCGATGGCACCTACAGGAGGCCCCCCGGCGTCCACAACTCAGCCTACATC GGATGCCCATCGGATCCTGACCTCCCAGCCGATGTGCAGACACCATCCTCGGTGGAACTGGGGAGGTATCCAGCCCTTCCCTTCCCGGCC TCCCAGTACATCCCACCCCAGCCGTCCATCGAGGAGGCACGCCAGACCATGCACTCCCTCCTGGACGACGCCTTTGCCCTCGTGGCCCCC AGCAGCCAGCCTGCCAGCACCGCAGGTGTAGGCCCCGGAGTCCCACCCGGCCTGCCCGCAAACAGCACCCCTTCCCAGGAAGAGAGGCGA GCCACCCAGTGGGGGTCCTTCTACAGCCCAGCCCAGACGGCCAACAATCCCTGCAGTGACTTGATTAGAGACCAAGGATTTCGTGGTGAT GGAGGATCAACCACAGGTTTGTCTGCTACCCCCCCTGCCTCATTACCTGGCTCACTAACTAACGTGAAAGCCTTACAGAAATCTCCAGGA CCTCAGCGAGAAAGGAAGTCATCTTCATCCTCAGAAGACAGGAATCGAATGAAAACACTTGGTAGACGGGACTCGAGTGATGATTGGGAG ATTCCTGATGGGCAGATTACAGTGGGACAAAGAATTGGATCTGGATCATTTGGAACAGTCTACAAGGGAAAGTGGCATGGTGATGTGGCA GTGAAAATGTTGAATGTGACAGCACCTACACCTCAGCAGTTACAAGCCTTCAAAAATGAAGTAGGAGTACTCAGGAAAACACGACATGTG AATATCCTACTCTTCATGGGCTATTCCACAAAGCCACAACTGGCTATTGTTACCCAGTGGTGTGAGGGCTCCAGCTTGTATCACCATCTC CATATCATTGAGACCAAATTTGAGATGATCAAACTTATAGATATTGCACGACAGACTGCACAGGGCATGGATTACTTACACGCCAAGTCA ATCATCCACAGAGACCTCAAGAGTAATAATATATTTCTTCATGAAGACCTCACAGTAAAAATAGGTGATTTTGGTCTAGCTACAGTGAAA TCTCGATGGAGTGGGTCCCATCAGTTTGAACAGTTGTCTGGATCCATTTTGTGGATGGCACCAGAAGTCATCAGAATGCAAGATAAAAAT CCATACAGCTTTCAGTCAGATGTATATGCATTTGGAATTGTTCTGTATGAATTGATGACTGGACAGTTACCTTATTCAAACATCAACAAC AGGGACCAGATAATTTTTATGGTGGGACGAGGATACCTGTCTCCAGATCTCAGTAAGGTACGGAGTAACTGTCCAAAAGCCATGAAGAGA TTAATGGCAGAGTGCCTCAAAAAGAAAAGAGATGAGAGACCACTCTTTCCCCAAATTCTCGCCTCTATTGAGCTGCTGGCCCGCTCATTG CCAAAAATTCACCGCAGTGCATCAGAACCCTCCTTGAATCGGGCTGGTTTCCAAACAGAGGATTTTAGTCTATATGCTTGTGCTTCTCCA AAAACACCCATCCAGGCAGGGGGATATGGTGCGTTTCCTGTCCACTGAAACAAATGAGTGAGAGAGTTCAGGAGAGTAGCAACAAAAGGA >In-frame_KIAA1549_ENST00000440172_chr7_138545885_-_BRAF_ENST00000288602_chr7_140487384_-_6575nt GACCCGAGAGCCGCTGAGCCGCGAGGCCGGGCCGGGGCGCCGGCCGGGAATGCCGGGGGCGCGGCGCCGACGCCGAGGCGCGGCCATGGA GGGGAAGCCCCGCGCCGGGGTCGCGCTGGCCCCGGGGCCGAGCGGCCGACGGCCTTCCGCCCGCTGCGCCCGCCGCCGCCGCCCGGGGCT GCTGCTTCCTGGCCTCTGGCTGCTGCTGCTGGCCCGGCCGGCCTCGTGCGCCCCAGATGAGCTCTCTCCGGAACAGCACAACCTTTCTTT ATACTCCATGGAGCTCGTGCTGAAGAAAAGCACTGGGCACAGCGCTGCACAAGTGGCCTTAACAGAAACTGCTCCCGGCTCCCAGCACAG CAGTCCTCTCCATGTCACAGCCCCGCCGTCTGCCACTACTTTTGATACAGCCTTTTTTAACCAAGGAAAACAGACCAAAAGTACAGCAGA TCCCAGCATCTTTGTGGCAACTTACGTGTCAGTGACGAGTAAAGAGGTGGCCGTCAATGACGATGAGATGGATAACTTTCTGCCAGATAC TCACTGGACCACTCCACGGATGGTTTCTCCAATACAGTATATCACAGTCAGCCCACCAGGGCTGCCCAGGGAAGCATTAGAACCTATGCT CACTCCATCATTACCCATGGTTTCTTTACAAGATGAAGAAGTGACATCGGGCTGGCAGAACACAACGCGACAACCAGCGGCATATGCTGA GTCCGCCAGTCATTTCCACACCTTTCGGTCAGCTTTTCGCACCTCTGAGGGCATCGTTCCAACTCCTGGCAGGAATTTGGTGCTTTATCC TACTGATGCTTACAGTCATTTATCAAGCAGGACTCTGCCAGAGATTGTGGCTTCCCTAACAGAGGGTGTGGAAACCACCCTTTTTTTAAG CTCCCGGTCTTTAATGCCACAGCCGTTAGGCGACGGCATTACTATACCGTTGCCCTCCTTGGGGGAGGTCTCACAGCCTCCAGAGGAGGT TTGGGCCACAAGTGCAGACAGATACACTGATGTGACCACTGTGTTGAGTCAAAGCCTAGAAGAAACCATCTCTCCAAGAACATACCCCAC TGTGACTGCATCGCACGCAGCCCTTGCATTCAGCAGGACACATTCTCCATTGCTTTCAACTCCTCTTGCATTTGCGTCCTCTGCTTCACC AACTGATGTTTCATCTAACCCCTTTCTCCCTAGCGACTCCAGCAAAACATCCGAATTGCATAGCAATTCAGCCCTCCCCGGTCCTGTGGA CAACACTCATATCCTGAGCCCGGTGTCCTCATTCAGACCATACACTTGGTGTGCGGCCTGCACTGTGCCTTCACCTCAGCAAGTTCTGGC CACGAGCCTCATGGAGAAAGACGTGGGATCAGGGGATGGTGCCGAGACTCTGTGCATGACCGTGCTGGAAGAAAGCAGCATCTCTCTAAT GAGTAGCGTCGTAGCAGACTTCTCTGAATTTGAGGAAGATCCTCAAGTATTTAATACGCTTTTCCCCTCCAGACCTATCGTCCCACTTTC TTCTAGATCCATGGAAATCTCAGAGACGAGTGTTGGCATTTCTGCCGAGGTGGATATGAGTAGTGTTACAACCACACAGGTTCCCCCTGC CCACGGCCGCCTCTCTGTGCCGGCGTCACTTGATCCTACTGCTGGCTCCTTGTCTGTTGCTGAAACCCAAGTGACGCCATCCAGCGTGAC CACTGCATTTTTCTCGGTCATCACCAGCATTCTCCTTGACTCATCTTTCTCTGTCATAGCAAACAAAAACACACCGTCGCTTGCCGTCAG AGACCCGAGTGTTTTTACGCCTTATAGTCTGGTTCCTTCAGTGGAGTCTTCACTTTTCTCTGACCAAGAACGTTCCAGTTTTTCTGAGCA TAAACCCAGAGGTGCTTTGGATTTTGCATCCAGCTTTTTCTCAACACCCCCGCTGGAACTCAGCGGCTCCATCTCTTCGCCTTCGGAAGC ACCTGCGTCTCTGTCTCTGATGCCGAGTGACTTGTCCCCCTTCACATCTCAGTCTTTTTCTCCCTTGGTTGAGACATTTACATTGTTTGA CTCTAGTGATCTGCAGTCATCTCAGCTGTCTCTTCCCAGTTCCACAAATCTTGAGTTTTCGCAGCTCCAGCCAAGTTCCGAGCTGCCTTT AAACACCATCATGTTGCTACCTAGCCGTTCTGAGGTGTCACCATGGTCAAGCTTCCCTTCTGATTCTCTCGAGTTTGTTGAAGCGTCTAC GGTTTCACTGACGGATTCAGAAGCTCATTTTACCTCAGCTTTCATTGAAACTACCTCCTATCTTGAGTCTTCACTCATTTCCCATGAATC CGCAGTCACTGCACTGGTGCCCCCCGGCTCTGAGTCTTTTGACATTTTGACTGCCGGGATTCAAGCAACATCACCATTGACCACTGTCCA CACAACGCCCATTTTAACTGAGTCTTCTTTGTTCTCAACTCTGACACCTCCTGACGACCAAATCAGTGCTCTAGACGGTCACGTGTCTGT CCTGGCCTCTTTCTCCAAAGCCATTCCCACTGGTACGGTGTTGATCACTGACGCGTACCTGCCATCAGGATCCTCGTTTGTTTCTGAAGC AACCCCCTTCCCTCTGCCCACAGAGCTGACCGTCGTGGGCCCATCACTCACACCCACAGAGGTGCCACTGAACACCTCCACGGAAGTGAG CACAACCAGCACCGGTGCTGCCACTGGTGGTCCCCTCGACTCCACCCTGATGGGTGACGCCGCAAGTCAGAGCCCCCCAGAGAGTAGTGC TGCTCCTCCCCTGCCATCCCTGCGTCCCGTGACTGCCTTCACTCTCGAAGCAACAGTCGACACACCAACACTGGCTACTGCCAAGCCGCC ATATGTTTGTGATATCACAGTCCCCGATGCCTATCTGATCACAACTGTGCTGGCCAGAAGAGCTGTGCAGGAGTACATCATTACAGCAAT CAAAGAAGTACTGAGGATTCACTTCAACCGTGCAGTGGAACTGAAGGTTTACGAACTATTTACTGACTTCACTTTTCTGGTAACATCCGG TCCTTTCGTTTACACGGCAATATCCGTCATAAATGTGCTTATAAACAGTAAGCTTGTCCGTGACCAGACTCCTTTAATCCTGTCTGTGAA ACCTTCTTTCCTTGTGCCAGAGTCCAGGTTCCAAGTTCAAACAGTACTTCAGTTTGTGCCTCCGAGTGTGGATACTGGCTTCTGCAACTT CACCCAGCGCATTGAGAAAGGCCTAATGACAGCTCTCTTTGAAGTGAGAAAACACCACCAGGGAACGTATAACCTCACGGTGCAGATCTT GAATATCACCATCAGTTCCTCAAGGGTGACTCCTCGGCGGGGCCCGGTGAATATCATCTTTGCGGTTAAAAGCACACAGGGATTTTTGAA TGGGTCGGAAGTGAGCGAGCTGCTCAGAAACTTGAGTGTGGTGGAGTTCAGTTTCTATCTGGGATACCCAGTGCTGCAGATCGCAGAGCC CTTCCAGTATCCACAGCTCAACTTATCTCAGTTGCTGAAGTCCTCTTGGGTCAGAACAGTTCTCCTGGGCGTCATGGAGAAGCAACTCCA GAATGAAGTGTTTCAAGCCGAGATGGAACGCAAGCTGGCCCAGCTGCTCAGCGAGGTTTCCACCAGAAGGCGGATGTGGAGAAGGGCCAC TGTAGCTGCAGGGAACAGTGTGGTGCAGGTGGTAAATGTGTCGAGGCTGGAGGGAGATGACAATCCGGTACAGCTCATCTACTTTGTGGA GGATCAAGATGGAGAAAGACTCAGTGCAGTCAAGTCTTCGGACCTGATTAACAAAATGGACCTCCAGAGAGCAGCCATCATCTTGGGTTA CCGAATTCAAGGTGTCATTGCCCAGCCTGTCGACAGGGTGAAGAGGCCGTCTCCGGAATCCCAGAGCAACAACTTGTGGGTCATTGTTGG CGTGGTCATCCCAGTGCTGGTGGTGATGGTGATTGTTGTCATCCTCTACTGGAAACTATGCCGCACAGACAAGCTAGACTTTCAGCCTGA CACTGTGGCCAACATTCAGCAGCGTCAGAAGCTGCAGATCCCTAGTGTGAAGGGCTTCGATTTTGCTAAGCAGCATCTGGGTCAGCACAA TAAAGACGACATATTGATTATTCATGAGCCAGCGCCACTGCCAGGACCTCTGAAGGACCACACCACGCCCTCGGAAAATGGAGACGTGCC AAGCCCCAAGTCAAAGATCCCTTCCAAGAATGTTCGTCACAGAGGAAGAGTTTCTCCCTCAGATGCTGACTCTACGGTCAGTGAAGAGTC CAGCGAGAGGGACGCAGGAGATAAGACGCCGGGAGCCGTCAACGATGGCAGGTCCCACAGAGCTCCGCAGAGCGGGCCACCACTGCCCAG TTCGGGAAATGAGCAGCACTCATCAGCCTCCATCTTCGAGCACGTGGACAGGATCTCCCGCCCCCCGGAGGCTAGCCGGCGGGTCCCCAG TAAGATCCAGCTTATCGCCATGCAGCCGATCCCGGCACCTCCCGTCCAGCGCCCCTCCCCAGCCGACCGAGTGGCGGAAAGCAATAAAAT CAACAAAGAGATTCAGACCGCGCTGCGGCACAAGTCTGAGATCGAGCACCATCGCAACAAGATCCGCCTGCGCGCCAAGCGCCGCGGGCA CTACGAGTTCCCGGTGGTAGACGACCTGTCCTCGGGCGACACTAAGGAGCGACACCGGGTGTACCGCAGGGCACAGATGCAGATCGACAA GATCCTGGACCCCACGGCCAGCGTGCCCTCCGTGTTCATAGAGCCCAGGAAGAGCTCACGGATAAAACGTTCTCCCAAGCCTCGCCGGAA ACACCAGGTCAACGGCTGTCCTGCCGACGCTGAGAAGGACCGGCTCATCACCACAGACAGCGATGGCACCTACAGGAGGCCCCCCGGCGT CCACAACTCAGCCTACATCGGATGCCCATCGGATCCTGACCTCCCAGCCGATGTGCAGACACCATCCTCGGTGGAACTGGGGAGGTATCC AGCCCTTCCCTTCCCGGCCTCCCAGTACATCCCACCCCAGCCGTCCATCGAGGAGGCACGCCAGACCATGCACTCCCTCCTGGACGACGC CTTTGCCCTCGTGGCCCCCAGCAGCCAGCCTGCCAGCACCGCAGGTGTAGGCCCCGGAGTCCCACCCGGCCTGCCCGCAAACAGCACCCC TTCCCAGGAAGAGAGGCGAGCCACCCAGTGGGGGTCCTTCTACAGCCCAGCCCAGACGGCCAACAATCCCTGCAGTGACTTGATTAGAGA CCAAGGATTTCGTGGTGATGGAGGATCAACCACAGGTTTGTCTGCTACCCCCCCTGCCTCATTACCTGGCTCACTAACTAACGTGAAAGC CTTACAGAAATCTCCAGGACCTCAGCGAGAAAGGAAGTCATCTTCATCCTCAGAAGACAGGAATCGAATGAAAACACTTGGTAGACGGGA CTCGAGTGATGATTGGGAGATTCCTGATGGGCAGATTACAGTGGGACAAAGAATTGGATCTGGATCATTTGGAACAGTCTACAAGGGAAA GTGGCATGGTGATGTGGCAGTGAAAATGTTGAATGTGACAGCACCTACACCTCAGCAGTTACAAGCCTTCAAAAATGAAGTAGGAGTACT CAGGAAAACACGACATGTGAATATCCTACTCTTCATGGGCTATTCCACAAAGCCACAACTGGCTATTGTTACCCAGTGGTGTGAGGGCTC CAGCTTGTATCACCATCTCCATATCATTGAGACCAAATTTGAGATGATCAAACTTATAGATATTGCACGACAGACTGCACAGGGCATGGA TTACTTACACGCCAAGTCAATCATCCACAGAGACCTCAAGAGTAATAATATATTTCTTCATGAAGACCTCACAGTAAAAATAGGTGATTT TGGTCTAGCTACAGTGAAATCTCGATGGAGTGGGTCCCATCAGTTTGAACAGTTGTCTGGATCCATTTTGTGGATGGCACCAGAAGTCAT CAGAATGCAAGATAAAAATCCATACAGCTTTCAGTCAGATGTATATGCATTTGGAATTGTTCTGTATGAATTGATGACTGGACAGTTACC TTATTCAAACATCAACAACAGGGACCAGATAATTTTTATGGTGGGACGAGGATACCTGTCTCCAGATCTCAGTAAGGTACGGAGTAACTG TCCAAAAGCCATGAAGAGATTAATGGCAGAGTGCCTCAAAAAGAAAAGAGATGAGAGACCACTCTTTCCCCAAATTCTCGCCTCTATTGA GCTGCTGGCCCGCTCATTGCCAAAAATTCACCGCAGTGCATCAGAACCCTCCTTGAATCGGGCTGGTTTCCAAACAGAGGATTTTAGTCT ATATGCTTGTGCTTCTCCAAAAACACCCATCCAGGCAGGGGGATATGGTGCGTTTCCTGTCCACTGAAACAAATGAGTGAGAGAGTTCAG GAGAGTAGCAACAAAAGGAAAATAAATGAACATATGTTTGCTTATATGTTAAATTGAATAAAATACTCTCTTTTTTTTTAAGGTGAACCA >In-frame_KIAA1549_ENST00000422774_chr7_138545885_-_BRAF_ENST00000288602_chr7_140487384_-_6575nt GACCCGAGAGCCGCTGAGCCGCGAGGCCGGGCCGGGGCGCCGGCCGGGAATGCCGGGGGCGCGGCGCCGACGCCGAGGCGCGGCCATGGA GGGGAAGCCCCGCGCCGGGGTCGCGCTGGCCCCGGGGCCGAGCGGCCGACGGCCTTCCGCCCGCTGCGCCCGCCGCCGCCGCCCGGGGCT GCTGCTTCCTGGCCTCTGGCTGCTGCTGCTGGCCCGGCCGGCCTCGTGCGCCCCAGATGAGCTCTCTCCGGAACAGCACAACCTTTCTTT ATACTCCATGGAGCTCGTGCTGAAGAAAAGCACTGGGCACAGCGCTGCACAAGTGGCCTTAACAGAAACTGCTCCCGGCTCCCAGCACAG CAGTCCTCTCCATGTCACAGCCCCGCCGTCTGCCACTACTTTTGATACAGCCTTTTTTAACCAAGGAAAACAGACCAAAAGTACAGCAGA TCCCAGCATCTTTGTGGCAACTTACGTGTCAGTGACGAGTAAAGAGGTGGCCGTCAATGACGATGAGATGGATAACTTTCTGCCAGATAC TCACTGGACCACTCCACGGATGGTTTCTCCAATACAGTATATCACAGTCAGCCCACCAGGGCTGCCCAGGGAAGCATTAGAACCTATGCT CACTCCATCATTACCCATGGTTTCTTTACAAGATGAAGAAGTGACATCGGGCTGGCAGAACACAACGCGACAACCAGCGGCATATGCTGA GTCCGCCAGTCATTTCCACACCTTTCGGTCAGCTTTTCGCACCTCTGAGGGCATCGTTCCAACTCCTGGCAGGAATTTGGTGCTTTATCC TACTGATGCTTACAGTCATTTATCAAGCAGGACTCTGCCAGAGATTGTGGCTTCCCTAACAGAGGGTGTGGAAACCACCCTTTTTTTAAG CTCCCGGTCTTTAATGCCACAGCCGTTAGGCGACGGCATTACTATACCGTTGCCCTCCTTGGGGGAGGTCTCACAGCCTCCAGAGGAGGT TTGGGCCACAAGTGCAGACAGATACACTGATGTGACCACTGTGTTGAGTCAAAGCCTAGAAGAAACCATCTCTCCAAGAACATACCCCAC TGTGACTGCATCGCACGCAGCCCTTGCATTCAGCAGGACACATTCTCCATTGCTTTCAACTCCTCTTGCATTTGCGTCCTCTGCTTCACC AACTGATGTTTCATCTAACCCCTTTCTCCCTAGCGACTCCAGCAAAACATCCGAATTGCATAGCAATTCAGCCCTCCCCGGTCCTGTGGA CAACACTCATATCCTGAGCCCGGTGTCCTCATTCAGACCATACACTTGGTGTGCGGCCTGCACTGTGCCTTCACCTCAGCAAGTTCTGGC CACGAGCCTCATGGAGAAAGACGTGGGATCAGGGGATGGTGCCGAGACTCTGTGCATGACCGTGCTGGAAGAAAGCAGCATCTCTCTAAT GAGTAGCGTCGTAGCAGACTTCTCTGAATTTGAGGAAGATCCTCAAGTATTTAATACGCTTTTCCCCTCCAGACCTATCGTCCCACTTTC TTCTAGATCCATGGAAATCTCAGAGACGAGTGTTGGCATTTCTGCCGAGGTGGATATGAGTAGTGTTACAACCACACAGGTTCCCCCTGC CCACGGCCGCCTCTCTGTGCCGGCGTCACTTGATCCTACTGCTGGCTCCTTGTCTGTTGCTGAAACCCAAGTGACGCCATCCAGCGTGAC CACTGCATTTTTCTCGGTCATCACCAGCATTCTCCTTGACTCATCTTTCTCTGTCATAGCAAACAAAAACACACCGTCGCTTGCCGTCAG AGACCCGAGTGTTTTTACGCCTTATAGTCTGGTTCCTTCAGTGGAGTCTTCACTTTTCTCTGACCAAGAACGTTCCAGTTTTTCTGAGCA TAAACCCAGAGGTGCTTTGGATTTTGCATCCAGCTTTTTCTCAACACCCCCGCTGGAACTCAGCGGCTCCATCTCTTCGCCTTCGGAAGC ACCTGCGTCTCTGTCTCTGATGCCGAGTGACTTGTCCCCCTTCACATCTCAGTCTTTTTCTCCCTTGGTTGAGACATTTACATTGTTTGA CTCTAGTGATCTGCAGTCATCTCAGCTGTCTCTTCCCAGTTCCACAAATCTTGAGTTTTCGCAGCTCCAGCCAAGTTCCGAGCTGCCTTT AAACACCATCATGTTGCTACCTAGCCGTTCTGAGGTGTCACCATGGTCAAGCTTCCCTTCTGATTCTCTCGAGTTTGTTGAAGCGTCTAC GGTTTCACTGACGGATTCAGAAGCTCATTTTACCTCAGCTTTCATTGAAACTACCTCCTATCTTGAGTCTTCACTCATTTCCCATGAATC CGCAGTCACTGCACTGGTGCCCCCCGGCTCTGAGTCTTTTGACATTTTGACTGCCGGGATTCAAGCAACATCACCATTGACCACTGTCCA CACAACGCCCATTTTAACTGAGTCTTCTTTGTTCTCAACTCTGACACCTCCTGACGACCAAATCAGTGCTCTAGACGGTCACGTGTCTGT CCTGGCCTCTTTCTCCAAAGCCATTCCCACTGGTACGGTGTTGATCACTGACGCGTACCTGCCATCAGGATCCTCGTTTGTTTCTGAAGC AACCCCCTTCCCTCTGCCCACAGAGCTGACCGTCGTGGGCCCATCACTCACACCCACAGAGGTGCCACTGAACACCTCCACGGAAGTGAG CACAACCAGCACCGGTGCTGCCACTGGTGGTCCCCTCGACTCCACCCTGATGGGTGACGCCGCAAGTCAGAGCCCCCCAGAGAGTAGTGC TGCTCCTCCCCTGCCATCCCTGCGTCCCGTGACTGCCTTCACTCTCGAAGCAACAGTCGACACACCAACACTGGCTACTGCCAAGCCGCC ATATGTTTGTGATATCACAGTCCCCGATGCCTATCTGATCACAACTGTGCTGGCCAGAAGAGCTGTGCAGGAGTACATCATTACAGCAAT CAAAGAAGTACTGAGGATTCACTTCAACCGTGCAGTGGAACTGAAGGTTTACGAACTATTTACTGACTTCACTTTTCTGGTAACATCCGG TCCTTTCGTTTACACGGCAATATCCGTCATAAATGTGCTTATAAACAGTAAGCTTGTCCGTGACCAGACTCCTTTAATCCTGTCTGTGAA ACCTTCTTTCCTTGTGCCAGAGTCCAGGTTCCAAGTTCAAACAGTACTTCAGTTTGTGCCTCCGAGTGTGGATACTGGCTTCTGCAACTT CACCCAGCGCATTGAGAAAGGCCTAATGACAGCTCTCTTTGAAGTGAGAAAACACCACCAGGGAACGTATAACCTCACGGTGCAGATCTT GAATATCACCATCAGTTCCTCAAGGGTGACTCCTCGGCGGGGCCCGGTGAATATCATCTTTGCGGTTAAAAGCACACAGGGATTTTTGAA TGGGTCGGAAGTGAGCGAGCTGCTCAGAAACTTGAGTGTGGTGGAGTTCAGTTTCTATCTGGGATACCCAGTGCTGCAGATCGCAGAGCC CTTCCAGTATCCACAGCTCAACTTATCTCAGTTGCTGAAGTCCTCTTGGGTCAGAACAGTTCTCCTGGGCGTCATGGAGAAGCAACTCCA GAATGAAGTGTTTCAAGCCGAGATGGAACGCAAGCTGGCCCAGCTGCTCAGCGAGGTTTCCACCAGAAGGCGGATGTGGAGAAGGGCCAC TGTAGCTGCAGGGAACAGTGTGGTGCAGGTGGTAAATGTGTCGAGGCTGGAGGGAGATGACAATCCGGTACAGCTCATCTACTTTGTGGA GGATCAAGATGGAGAAAGACTCAGTGCAGTCAAGTCTTCGGACCTGATTAACAAAATGGACCTCCAGAGAGCAGCCATCATCTTGGGTTA CCGAATTCAAGGTGTCATTGCCCAGCCTGTCGACAGGGTGAAGAGGCCGTCTCCGGAATCCCAGAGCAACAACTTGTGGGTCATTGTTGG CGTGGTCATCCCAGTGCTGGTGGTGATGGTGATTGTTGTCATCCTCTACTGGAAACTATGCCGCACAGACAAGCTAGACTTTCAGCCTGA CACTGTGGCCAACATTCAGCAGCGTCAGAAGCTGCAGATCCCTAGTGTGAAGGGCTTCGATTTTGCTAAGCAGCATCTGGGTCAGCACAA TAAAGACGACATATTGATTATTCATGAGCCAGCGCCACTGCCAGGACCTCTGAAGGACCACACCACGCCCTCGGAAAATGGAGACGTGCC AAGCCCCAAGTCAAAGATCCCTTCCAAGAATGTTCGTCACAGAGGAAGAGTTTCTCCCTCAGATGCTGACTCTACGGTCAGTGAAGAGTC CAGCGAGAGGGACGCAGGAGATAAGACGCCGGGAGCCGTCAACGATGGCAGGTCCCACAGAGCTCCGCAGAGCGGGCCACCACTGCCCAG TTCGGGAAATGAGCAGCACTCATCAGCCTCCATCTTCGAGCACGTGGACAGGATCTCCCGCCCCCCGGAGGCTAGCCGGCGGGTCCCCAG TAAGATCCAGCTTATCGCCATGCAGCCGATCCCGGCACCTCCCGTCCAGCGCCCCTCCCCAGCCGACCGAGTGGCGGAAAGCAATAAAAT CAACAAAGAGATTCAGACCGCGCTGCGGCACAAGTCTGAGATCGAGCACCATCGCAACAAGATCCGCCTGCGCGCCAAGCGCCGCGGGCA CTACGAGTTCCCGGTGGTAGACGACCTGTCCTCGGGCGACACTAAGGAGCGACACCGGGTGTACCGCAGGGCACAGATGCAGATCGACAA GATCCTGGACCCCACGGCCAGCGTGCCCTCCGTGTTCATAGAGCCCAGGAAGAGCTCACGGATAAAACGTTCTCCCAAGCCTCGCCGGAA ACACCAGGTCAACGGCTGTCCTGCCGACGCTGAGAAGGACCGGCTCATCACCACAGACAGCGATGGCACCTACAGGAGGCCCCCCGGCGT CCACAACTCAGCCTACATCGGATGCCCATCGGATCCTGACCTCCCAGCCGATGTGCAGACACCATCCTCGGTGGAACTGGGGAGGTATCC AGCCCTTCCCTTCCCGGCCTCCCAGTACATCCCACCCCAGCCGTCCATCGAGGAGGCACGCCAGACCATGCACTCCCTCCTGGACGACGC CTTTGCCCTCGTGGCCCCCAGCAGCCAGCCTGCCAGCACCGCAGGTGTAGGCCCCGGAGTCCCACCCGGCCTGCCCGCAAACAGCACCCC TTCCCAGGAAGAGAGGCGAGCCACCCAGTGGGGGTCCTTCTACAGCCCAGCCCAGACGGCCAACAATCCCTGCAGTGACTTGATTAGAGA CCAAGGATTTCGTGGTGATGGAGGATCAACCACAGGTTTGTCTGCTACCCCCCCTGCCTCATTACCTGGCTCACTAACTAACGTGAAAGC CTTACAGAAATCTCCAGGACCTCAGCGAGAAAGGAAGTCATCTTCATCCTCAGAAGACAGGAATCGAATGAAAACACTTGGTAGACGGGA CTCGAGTGATGATTGGGAGATTCCTGATGGGCAGATTACAGTGGGACAAAGAATTGGATCTGGATCATTTGGAACAGTCTACAAGGGAAA GTGGCATGGTGATGTGGCAGTGAAAATGTTGAATGTGACAGCACCTACACCTCAGCAGTTACAAGCCTTCAAAAATGAAGTAGGAGTACT CAGGAAAACACGACATGTGAATATCCTACTCTTCATGGGCTATTCCACAAAGCCACAACTGGCTATTGTTACCCAGTGGTGTGAGGGCTC CAGCTTGTATCACCATCTCCATATCATTGAGACCAAATTTGAGATGATCAAACTTATAGATATTGCACGACAGACTGCACAGGGCATGGA TTACTTACACGCCAAGTCAATCATCCACAGAGACCTCAAGAGTAATAATATATTTCTTCATGAAGACCTCACAGTAAAAATAGGTGATTT TGGTCTAGCTACAGTGAAATCTCGATGGAGTGGGTCCCATCAGTTTGAACAGTTGTCTGGATCCATTTTGTGGATGGCACCAGAAGTCAT CAGAATGCAAGATAAAAATCCATACAGCTTTCAGTCAGATGTATATGCATTTGGAATTGTTCTGTATGAATTGATGACTGGACAGTTACC TTATTCAAACATCAACAACAGGGACCAGATAATTTTTATGGTGGGACGAGGATACCTGTCTCCAGATCTCAGTAAGGTACGGAGTAACTG TCCAAAAGCCATGAAGAGATTAATGGCAGAGTGCCTCAAAAAGAAAAGAGATGAGAGACCACTCTTTCCCCAAATTCTCGCCTCTATTGA GCTGCTGGCCCGCTCATTGCCAAAAATTCACCGCAGTGCATCAGAACCCTCCTTGAATCGGGCTGGTTTCCAAACAGAGGATTTTAGTCT ATATGCTTGTGCTTCTCCAAAAACACCCATCCAGGCAGGGGGATATGGTGCGTTTCCTGTCCACTGAAACAAATGAGTGAGAGAGTTCAG GAGAGTAGCAACAAAAGGAAAATAAATGAACATATGTTTGCTTATATGTTAAATTGAATAAAATACTCTCTTTTTTTTTAAGGTGAACCA |
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FusionGenePPI for KIAA1549_BRAF |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| KIAA1549 | DST, MYO5B, CADPS, ITSN2, MBD5, LATS1, LATS2, LGALS3, LGALS8, LGALS9, FCN1, HLA-F, TMEM17, CTDSPL, SERPINA12, TRIM25 | BRAF | YWHAB, YWHAG, YWHAQ, YWHAZ, SFN, HRAS, AKT1, MAPK3, RAP1GAP, RAF1, MRAS, RAP1A, PAK2, TERF1, CCDC88A, NEDD4L, MAP2K1, RNF149, KSR1, BRAP, PRKCE, RPS6KB2, HSP90AA1, BRAF, YWHAE, HSPA5, MAP2K2, HSPA1A, HSPA8, YWHAH, HSPA9, ARAF, CDC37, HSP90AB1, PHKB, LIMK1, IQGAP1, MAPK1, BAD, LIPF, MUS81, FBXW7, FGFR2, BRCA2, VHL, FNTA, HDAC2, PIK3CA, EGFR, PTEN, FNIP1, FNIP2, RAB3GAP1, KRAS, KIAA0141, FKBPL, ARMCX3, KCNC4, RPTOR, CYLD, NRAS |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for KIAA1549_BRAF |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
| Tgene | BRAF | P15056 | DB08881 | Vemurafenib | Serine/threonine-protein kinase B-raf | small molecule | approved |
| Tgene | BRAF | P15056 | DB08896 | Regorafenib | Serine/threonine-protein kinase B-raf | small molecule | approved |
| Tgene | BRAF | P15056 | DB00398 | Sorafenib | Serine/threonine-protein kinase B-raf | small molecule | approved|investigational |
| Tgene | BRAF | P15056 | DB08912 | Dabrafenib | Serine/threonine-protein kinase B-raf | small molecule | approved|investigational |
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RelatedDiseases for KIAA1549_BRAF |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | KIAA1549 | C0004114 | Astrocytoma | 1 | CTD_human |
| Tgene | BRAF | C0025202 | melanoma | 21 | CTD_human |
| Tgene | BRAF | C1527249 | Colorectal Cancer | 8 | UNIPROT |
| Tgene | BRAF | C1275081 | Cardio-facio-cutaneous syndrome | 6 | CTD_human;ORPHANET;UNIPROT |
| Tgene | BRAF | C0009404 | Colorectal Neoplasms | 4 | CTD_human |
| Tgene | BRAF | C0040136 | Thyroid Neoplasm | 4 | CTD_human |
| Tgene | BRAF | C0024305 | Lymphoma, Non-Hodgkin | 3 | UNIPROT |
| Tgene | BRAF | C0684249 | Carcinoma of lung | 3 | UNIPROT |
| Tgene | BRAF | C3150970 | NOONAN SYNDROME 7 | 3 | CTD_human;UNIPROT |
| Tgene | BRAF | C0152013 | Adenocarcinoma of lung (disorder) | 2 | CTD_human |
| Tgene | BRAF | C0002448 | Ameloblastoma | 1 | CTD_human |
| Tgene | BRAF | C0004114 | Astrocytoma | 1 | CTD_human |
| Tgene | BRAF | C0010276 | Craniopharyngioma | 1 | CTD_human;ORPHANET |
| Tgene | BRAF | C0017638 | Glioma | 1 | CTD_human |
| Tgene | BRAF | C0022665 | Kidney Neoplasm | 1 | CTD_human |
| Tgene | BRAF | C0023903 | Liver neoplasms | 1 | CTD_human |
| Tgene | BRAF | C0024694 | Mandibular Neoplasms | 1 | CTD_human |
| Tgene | BRAF | C0028326 | Noonan Syndrome | 1 | CTD_human;ORPHANET |
| Tgene | BRAF | C0033578 | Prostatic Neoplasms | 1 | CTD_human |
| Tgene | BRAF | C0036920 | Sezary Syndrome | 1 | CTD_human |
| Tgene | BRAF | C0079773 | Lymphoma, T-Cell, Cutaneous | 1 | CTD_human |
| Tgene | BRAF | C0206686 | Adrenocortical carcinoma | 1 | CTD_human |
| Tgene | BRAF | C0206754 | Neuroendocrine Tumors | 1 | CTD_human |
| Tgene | BRAF | C0238463 | Papillary thyroid carcinoma | 1 | CTD_human;ORPHANET |
| Tgene | BRAF | C0587248 | Costello syndrome (disorder) | 1 | CTD_human |
| Tgene | BRAF | C0596263 | Carcinogenesis | 1 | CTD_human |
| Tgene | BRAF | C0920269 | Microsatellite Instability | 1 | CTD_human |
| Tgene | BRAF | C2239176 | Liver carcinoma | 1 | CTD_human |
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