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Fusion gene ID: 1866 |
FusionGeneSummary for ANKRD50_ANKRD50 |
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Fusion gene information | Fusion gene name: ANKRD50_ANKRD50 | Fusion gene ID: 1866 | Hgene | Tgene | Gene symbol | ANKRD50 | ANKRD50 | Gene ID | 57182 | 57182 |
Gene name | ankyrin repeat domain 50 | ankyrin repeat domain 50 | |
Synonyms | - | - | |
Cytomap | 4q28.1 | 4q28.1 | |
Type of gene | protein-coding | protein-coding | |
Description | ankyrin repeat domain-containing protein 50 | ankyrin repeat domain-containing protein 50 | |
Modification date | 20180522 | 20180522 | |
UniProtAcc | Q9ULJ7 | Q9ULJ7 | |
Ensembl transtripts involved in fusion gene | ENST00000504087, ENST00000515641, | ENST00000504087, ENST00000515641, | |
Fusion gene scores | * DoF score | 2 X 2 X 2=8 | 1 X 1 X 1=1 |
# samples | 2 | 1 | |
** MAII score | log2(2/8*10)=1.32192809488736 | log2(1/1*10)=3.32192809488736 | |
Context | PubMed: ANKRD50 [Title/Abstract] AND ANKRD50 [Title/Abstract] AND fusion [Title/Abstract] | ||
Functional or gene categories assigned by FusionGDB annotation |
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
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Partner | Gene | GO ID | GO term | PubMed ID |
![]() (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
ChiTaRS3.1 | CA336858 | ANKRD50 | chr4 | 125621279 | + | ANKRD50 | chr4 | 125620532 | + |
* LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
![]() * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
intron-intron | ENST00000504087 | ENST00000504087 | ANKRD50 | chr4 | 125621279 | + | ANKRD50 | chr4 | 125620532 | + |
intron-intron | ENST00000504087 | ENST00000515641 | ANKRD50 | chr4 | 125621279 | + | ANKRD50 | chr4 | 125620532 | + |
intron-intron | ENST00000515641 | ENST00000504087 | ANKRD50 | chr4 | 125621279 | + | ANKRD50 | chr4 | 125620532 | + |
intron-intron | ENST00000515641 | ENST00000515641 | ANKRD50 | chr4 | 125621279 | + | ANKRD50 | chr4 | 125620532 | + |
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FusionProtFeatures for ANKRD50_ANKRD50 |
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Hgene | Tgene |
ANKRD50 | ANKRD50 |
Involved in the endosome-to-plasma membrane traffickingand recycling of SNX27-retromer-dependent cargo proteins, such asGLUT1 (PubMed:25278552). | Involved in the endosome-to-plasma membrane traffickingand recycling of SNX27-retromer-dependent cargo proteins, such asGLUT1 (PubMed:25278552). |
![]() * Minus value of BPloci means that the break pointn is located before the CDS. |
- In-frame and retained protein feature among the 13 regional features. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
- In-frame and not-retained protein feature among the 13 regional features. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
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FusionGeneSequence for ANKRD50_ANKRD50 |
![]() (nt: nucleotides, aa: amino acids) |
* Fusion amino acid sequences. |
* Fusion transcript sequences (only coding sequence (CDS) region). |
* Fusion transcript sequences (Full-length transcript). |
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FusionGenePPI for ANKRD50_ANKRD50 |
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Hgene | Hgene's interactors | Tgene | Tgene's interactors |
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Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
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Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for ANKRD50_ANKRD50 |
![]() (DrugBank Version 5.1.0 2018-04-02) |
Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for ANKRD50_ANKRD50 |
![]() (DisGeNet 4.0) |
Partner | Gene | Disease ID | Disease name | # pubmeds | Source |