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Fusion gene ID: 18588 |
FusionGeneSummary for KIAA0319L_PHC2 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: KIAA0319L_PHC2 | Fusion gene ID: 18588 | Hgene | Tgene | Gene symbol | KIAA0319L | PHC2 | Gene ID | 79932 | 1912 |
| Gene name | KIAA0319 like | polyhomeotic homolog 2 | |
| Synonyms | AAVR|AAVRL | EDR2|HPH2|PH2 | |
| Cytomap | 1p34.3 | 1p35.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | dyslexia-associated protein KIAA0319-like proteinAAV receptorAAV receptor likeadeno-associated virus receptorpolycystic kidney disease 1-related | polyhomeotic-like protein 2early development regulator 2 (homolog of polyhomeotic 2)early development regulatory protein 2polyhomeotic 2polyhomeotic-like 2 | |
| Modification date | 20180523 | 20180519 | |
| UniProtAcc | Q8IZA0 | Q8IXK0 | |
| Ensembl transtripts involved in fusion gene | ENST00000325722, ENST00000373266, ENST00000485551, | ENST00000431992, ENST00000373422, ENST00000257118, ENST00000419414, ENST00000373416, ENST00000485928, ENST00000373418, | |
| Fusion gene scores | * DoF score | 14 X 8 X 10=1120 | 4 X 4 X 3=48 |
| # samples | 14 | 6 | |
| ** MAII score | log2(14/1120*10)=-3 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(6/48*10)=0.321928094887362 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
| Context | PubMed: KIAA0319L [Title/Abstract] AND PHC2 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | BRCA | TCGA-D8-A1XJ-01A | KIAA0319L | chr1 | 35907847 | - | PHC2 | chr1 | 33790620 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| Frame-shift | ENST00000325722 | ENST00000431992 | KIAA0319L | chr1 | 35907847 | - | PHC2 | chr1 | 33790620 | - |
| In-frame | ENST00000325722 | ENST00000373422 | KIAA0319L | chr1 | 35907847 | - | PHC2 | chr1 | 33790620 | - |
| Frame-shift | ENST00000325722 | ENST00000257118 | KIAA0319L | chr1 | 35907847 | - | PHC2 | chr1 | 33790620 | - |
| Frame-shift | ENST00000325722 | ENST00000419414 | KIAA0319L | chr1 | 35907847 | - | PHC2 | chr1 | 33790620 | - |
| 5CDS-intron | ENST00000325722 | ENST00000373416 | KIAA0319L | chr1 | 35907847 | - | PHC2 | chr1 | 33790620 | - |
| 5CDS-5UTR | ENST00000325722 | ENST00000485928 | KIAA0319L | chr1 | 35907847 | - | PHC2 | chr1 | 33790620 | - |
| 5CDS-5UTR | ENST00000325722 | ENST00000373418 | KIAA0319L | chr1 | 35907847 | - | PHC2 | chr1 | 33790620 | - |
| Frame-shift | ENST00000373266 | ENST00000431992 | KIAA0319L | chr1 | 35907847 | - | PHC2 | chr1 | 33790620 | - |
| In-frame | ENST00000373266 | ENST00000373422 | KIAA0319L | chr1 | 35907847 | - | PHC2 | chr1 | 33790620 | - |
| Frame-shift | ENST00000373266 | ENST00000257118 | KIAA0319L | chr1 | 35907847 | - | PHC2 | chr1 | 33790620 | - |
| Frame-shift | ENST00000373266 | ENST00000419414 | KIAA0319L | chr1 | 35907847 | - | PHC2 | chr1 | 33790620 | - |
| 5CDS-intron | ENST00000373266 | ENST00000373416 | KIAA0319L | chr1 | 35907847 | - | PHC2 | chr1 | 33790620 | - |
| 5CDS-5UTR | ENST00000373266 | ENST00000485928 | KIAA0319L | chr1 | 35907847 | - | PHC2 | chr1 | 33790620 | - |
| 5CDS-5UTR | ENST00000373266 | ENST00000373418 | KIAA0319L | chr1 | 35907847 | - | PHC2 | chr1 | 33790620 | - |
| 5UTR-3CDS | ENST00000485551 | ENST00000431992 | KIAA0319L | chr1 | 35907847 | - | PHC2 | chr1 | 33790620 | - |
| 5UTR-3CDS | ENST00000485551 | ENST00000373422 | KIAA0319L | chr1 | 35907847 | - | PHC2 | chr1 | 33790620 | - |
| 5UTR-3CDS | ENST00000485551 | ENST00000257118 | KIAA0319L | chr1 | 35907847 | - | PHC2 | chr1 | 33790620 | - |
| 5UTR-3CDS | ENST00000485551 | ENST00000419414 | KIAA0319L | chr1 | 35907847 | - | PHC2 | chr1 | 33790620 | - |
| 5UTR-intron | ENST00000485551 | ENST00000373416 | KIAA0319L | chr1 | 35907847 | - | PHC2 | chr1 | 33790620 | - |
| 5UTR-5UTR | ENST00000485551 | ENST00000485928 | KIAA0319L | chr1 | 35907847 | - | PHC2 | chr1 | 33790620 | - |
| 5UTR-5UTR | ENST00000485551 | ENST00000373418 | KIAA0319L | chr1 | 35907847 | - | PHC2 | chr1 | 33790620 | - |
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FusionProtFeatures for KIAA0319L_PHC2 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| KIAA0319L | PHC2 |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
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FusionGeneSequence for KIAA0319L_PHC2 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_KIAA0319L_ENST00000325722_chr1_35907847_-_PHC2_ENST00000373422_chr1_33790620_-_1008aa MEKRLGVKPNPASWILSGYYWQTSAKWLRSLYLFYTCFCFSVLWLSTDASESRCQQGKTQFGVGLRSGGENHLWLLEGTPSLQSCWAACC QDSACHVFWWLEGMCIQADCSRPQSCRAFRTHSSNSMLVFLKKFQTADDLGFLPEDDVPHLLGLGWNWASWRQSPPRAALRPAVSSSDQQ SLIRKLQKRGSPSDVVTPIVTQHSKVNDSNELGGLTTSGSAEVHKAITISSPLTTDLTAELSGGPKNVSVQPEISEGLATTPSTQQVKSS EKTQIAVPQPVAPSYSYATPTPQASFQSTSAPYPVIKELVVSAGESVQITLPKNEVQLNAYVLQEPPKGETYTYDWQLITHPRDYSGEME GKHSQILKLSKLTPGLYEFKVIVEGQNAHGEGYVNVTVKPEPRKNRPPIAIVSPQFQEISLPTTSTVIDGSQSTDDDKIVQYHWEELKGP LREEKISEDTAILKLSKLVPGNYTFSLTVVDSDGATNSTTANLTVNKAVDYPPVANAGPNQVITLPQNSITLFGNQSTDDHGITSYEWSL SPSSKGKVVEMQGVRTPTLQLSAMQEGDYTYQLTVTDTIGQQATAQVTVIVQPENNKPPQADAGPDKELTLPVDSTTLDGSKSSDDQKII SYLWEKTQGPDGVQLENANSSVATVTGLQVGTYVFTLTVKDERNLQSQSSVNVIVKEEINKPPIAKITGNVVITLPTSTAELDGSKSSDD KGIVSYLWTRDEGSPAAGEVLNHSDHHPILFLSNLVEGTYTFHLKVTDAKGESDTDRTTVEVKPDPRKNNLVEIILDINVSQLTERLKGM FIRQIGVLLGVLDSDIIVQKIQPYTEQSTKMVFFVQNEPPHQIFKGHEVAAMLKSELRKQKADFLIFRALEVNTVTCQLNCSDHGHCDSF TKRCICDPFWMENFIKVQLRDGDSNCEWSVLYVIIATFVIVVALGILSWTVICCCKRLPGDSRGIPCPGNRRASPAAAQGGPPDERHEHQ >In-frame_KIAA0319L_ENST00000373266_chr1_35907847_-_PHC2_ENST00000373422_chr1_33790620_-_445aa MQEGDYTYQLTVTDTIGQQATAQVTVIVQPENNKPPQADAGPDKELTLPVDSTTLDGSKSSDDQKIISYLWEKTQGPDGVQLENANSSVA TVTGLQVGTYVFTLTVKDERNLQSQSSVNVIVKEEINKPPIAKITGNVVITLPTSTAELDGSKSSDDKGIVSYLWTRDEGSPAAGEVLNH SDHHPILFLSNLVEGTYTFHLKVTDAKGESDTDRTTVEVKPDPRKNNLVEIILDINVSQLTERLKGMFIRQIGVLLGVLDSDIIVQKIQP YTEQSTKMVFFVQNEPPHQIFKGHEVAAMLKSELRKQKADFLIFRALEVNTVTCQLNCSDHGHCDSFTKRCICDPFWMENFIKVQLRDGD |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_KIAA0319L_ENST00000325722_chr1_35907847_-_PHC2_ENST00000373422_chr1_33790620_-_3025nt ATGGAGAAGAGGCTGGGAGTCAAGCCAAATCCTGCTTCCTGGATTTTATCAGGATATTATTGGCAGACATCTGCGAAGTGGTTGAGAAGC CTGTACCTGTTTTATACTTGCTTTTGCTTCAGCGTTCTGTGGTTGTCAACAGATGCCAGTGAGAGCAGGTGCCAGCAGGGGAAGACACAA TTTGGAGTTGGCCTGAGATCTGGGGGAGAAAATCACCTCTGGCTTCTTGAAGGAACCCCCTCTCTCCAGTCATGTTGGGCTGCCTGCTGC CAGGACTCTGCCTGCCATGTCTTTTGGTGGCTAGAAGGGATGTGCATTCAGGCAGACTGCAGCAGGCCCCAGAGCTGCCGGGCTTTTAGG ACACACTCCTCCAATTCCATGCTGGTGTTTTTAAAAAAATTCCAAACTGCAGATGATTTGGGCTTTCTACCTGAAGATGATGTACCACAT CTTCTGGGGCTAGGTTGGAACTGGGCATCTTGGAGGCAGAGCCCACCCAGAGCTGCACTCAGACCTGCTGTATCTTCCAGTGACCAGCAG AGCTTAATCAGGAAGCTTCAGAAGAGAGGTAGTCCCAGTGACGTAGTTACACCTATAGTGACACAGCATTCTAAAGTGAATGACTCCAAC GAATTAGGTGGTCTGACTACCAGTGGCTCTGCAGAGGTCCACAAGGCGATTACAATTTCCAGTCCCCTAACCACAGACCTGACTGCAGAG CTGTCTGGTGGGCCAAAGAATGTATCAGTGCAACCTGAAATATCAGAGGGTCTTGCTACTACGCCCAGCACTCAACAAGTAAAAAGTTCT GAGAAAACCCAGATTGCTGTCCCCCAGCCAGTGGCTCCCTCCTACAGTTATGCTACCCCTACCCCCCAGGCCTCTTTCCAGAGCACCTCA GCACCATACCCAGTTATAAAGGAACTGGTGGTATCTGCTGGAGAGAGTGTCCAGATAACCCTGCCTAAGAATGAAGTTCAATTAAATGCA TATGTTCTCCAAGAACCACCTAAAGGAGAAACCTACACCTACGACTGGCAGCTGATTACTCATCCTAGAGACTACAGTGGAGAAATGGAA GGGAAACATTCCCAGATCCTCAAACTATCGAAGCTCACTCCAGGCCTGTATGAATTCAAAGTGATTGTAGAGGGTCAAAATGCCCATGGG GAAGGCTATGTGAACGTGACAGTCAAGCCAGAGCCCCGTAAGAATCGGCCCCCCATTGCTATTGTGTCACCTCAGTTCCAGGAGATCTCT TTGCCAACCACTTCTACAGTCATTGATGGCAGTCAAAGCACTGATGATGATAAAATCGTTCAGTACCATTGGGAAGAACTTAAGGGGCCT CTAAGAGAAGAGAAGATTTCTGAAGATACAGCCATATTAAAACTAAGTAAACTCGTCCCTGGGAACTACACTTTCAGCTTGACTGTAGTA GACTCTGATGGAGCTACCAACTCTACTACTGCAAACCTGACAGTGAACAAAGCTGTGGATTACCCCCCTGTGGCCAACGCAGGCCCCAAC CAAGTGATCACCCTGCCCCAAAACTCCATCACCCTCTTTGGGAACCAGAGCACTGATGATCATGGCATCACCAGCTATGAGTGGTCACTC AGCCCAAGCAGCAAAGGGAAAGTGGTGGAGATGCAGGGTGTTAGAACACCAACCTTACAGCTCTCTGCGATGCAAGAAGGAGACTACACT TACCAGCTCACAGTGACTGACACAATAGGACAGCAGGCCACTGCTCAAGTGACTGTTATTGTGCAACCTGAAAACAATAAGCCTCCTCAG GCAGATGCAGGCCCAGATAAAGAGCTGACCCTTCCTGTGGATAGCACAACCCTGGATGGCAGCAAGAGCTCAGATGATCAGAAAATTATC TCATATCTCTGGGAAAAAACACAGGGACCTGATGGGGTGCAGCTCGAGAATGCTAACAGCAGTGTTGCTACTGTGACTGGGCTGCAAGTG GGGACCTATGTGTTCACCTTGACTGTCAAAGATGAGAGGAACCTGCAAAGCCAGAGCTCTGTGAATGTCATTGTCAAAGAAGAAATAAAC AAACCACCTATAGCCAAGATAACTGGGAATGTGGTGATTACCCTACCCACGAGCACAGCAGAGCTGGATGGCTCTAAGTCCTCAGATGAC AAGGGAATAGTCAGCTACCTCTGGACTCGAGATGAGGGGAGCCCAGCAGCAGGGGAGGTGTTAAATCACTCTGACCATCACCCTATCCTT TTTCTTTCAAACCTGGTTGAGGGAACCTACACTTTTCACCTGAAAGTGACCGATGCAAAGGGTGAGAGTGACACAGACCGGACCACTGTG GAGGTGAAACCTGATCCCAGGAAAAACAACCTGGTGGAGATCATCTTGGATATCAACGTCAGTCAGCTAACTGAGAGGCTGAAGGGGATG TTCATCCGCCAGATTGGGGTCCTCCTGGGGGTGCTGGATTCCGACATCATTGTGCAAAAGATTCAGCCGTACACGGAGCAGAGCACCAAA ATGGTATTTTTTGTTCAAAACGAGCCTCCCCACCAGATCTTCAAAGGCCATGAGGTGGCAGCGATGCTCAAGAGTGAGCTGCGGAAGCAA AAGGCAGACTTTTTGATATTCAGAGCCTTGGAAGTCAACACTGTCACATGTCAGCTGAACTGTTCCGACCATGGCCACTGTGACTCGTTC ACCAAACGCTGTATCTGTGACCCTTTTTGGATGGAGAATTTCATCAAGGTGCAGCTGAGGGATGGAGACAGCAACTGTGAGTGGAGCGTG TTATATGTTATCATTGCTACCTTTGTCATTGTTGTTGCCTTGGGAATCCTGTCTTGGACTGTGATCTGTTGTTGTAAGAGGCTGCCAGGA GATAGCAGAGGAATTCCGTGCCCAGGAAATCGACGGGCAAGCCCTGCTGCTGCTCAAGGAGGACCACCTGATGAGCGCCATGAACATCAA >In-frame_KIAA0319L_ENST00000373266_chr1_35907847_-_PHC2_ENST00000373422_chr1_33790620_-_1336nt ATGCAAGAAGGAGACTACACTTACCAGCTCACAGTGACTGACACAATAGGACAGCAGGCCACTGCTCAAGTGACTGTTATTGTGCAACCT GAAAACAATAAGCCTCCTCAGGCAGATGCAGGCCCAGATAAAGAGCTGACCCTTCCTGTGGATAGCACAACCCTGGATGGCAGCAAGAGC TCAGATGATCAGAAAATTATCTCATATCTCTGGGAAAAAACACAGGGACCTGATGGGGTGCAGCTCGAGAATGCTAACAGCAGTGTTGCT ACTGTGACTGGGCTGCAAGTGGGGACCTATGTGTTCACCTTGACTGTCAAAGATGAGAGGAACCTGCAAAGCCAGAGCTCTGTGAATGTC ATTGTCAAAGAAGAAATAAACAAACCACCTATAGCCAAGATAACTGGGAATGTGGTGATTACCCTACCCACGAGCACAGCAGAGCTGGAT GGCTCTAAGTCCTCAGATGACAAGGGAATAGTCAGCTACCTCTGGACTCGAGATGAGGGGAGCCCAGCAGCAGGGGAGGTGTTAAATCAC TCTGACCATCACCCTATCCTTTTTCTTTCAAACCTGGTTGAGGGAACCTACACTTTTCACCTGAAAGTGACCGATGCAAAGGGTGAGAGT GACACAGACCGGACCACTGTGGAGGTGAAACCTGATCCCAGGAAAAACAACCTGGTGGAGATCATCTTGGATATCAACGTCAGTCAGCTA ACTGAGAGGCTGAAGGGGATGTTCATCCGCCAGATTGGGGTCCTCCTGGGGGTGCTGGATTCCGACATCATTGTGCAAAAGATTCAGCCG TACACGGAGCAGAGCACCAAAATGGTATTTTTTGTTCAAAACGAGCCTCCCCACCAGATCTTCAAAGGCCATGAGGTGGCAGCGATGCTC AAGAGTGAGCTGCGGAAGCAAAAGGCAGACTTTTTGATATTCAGAGCCTTGGAAGTCAACACTGTCACATGTCAGCTGAACTGTTCCGAC CATGGCCACTGTGACTCGTTCACCAAACGCTGTATCTGTGACCCTTTTTGGATGGAGAATTTCATCAAGGTGCAGCTGAGGGATGGAGAC AGCAACTGTGAGTGGAGCGTGTTATATGTTATCATTGCTACCTTTGTCATTGTTGTTGCCTTGGGAATCCTGTCTTGGACTGTGATCTGT TGTTGTAAGAGGCTGCCAGGAGATAGCAGAGGAATTCCGTGCCCAGGAAATCGACGGGCAAGCCCTGCTGCTGCTCAAGGAGGACCACCT |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_KIAA0319L_ENST00000325722_chr1_35907847_-_PHC2_ENST00000373422_chr1_33790620_-_4499nt AGGAGGCGGTGTTTCCGGCCGCCGTCGCTGTCCAGGGAGGCTGAGGCGAGAGGTAGCTGTCCGGGTGGGGAGCCCGCACTACCTTCTTCC TCTTCCTCCTCCTCCTCCGGGTGAGGGGAGCGAAGGTTGGGGGTCCCCGAGCCCATGGACCAGGAGGAGGCGGAGGCCGCCGAGAGCCGG GGCCCCGCTATGTGGCCCTGAGCCCCGTGTACTGGTTCTGCCTGTCTGGAGGGCCATGGAGAAGAGGCTGGGAGTCAAGCCAAATCCTGC TTCCTGGATTTTATCAGGATATTATTGGCAGACATCTGCGAAGTGGTTGAGAAGCCTGTACCTGTTTTATACTTGCTTTTGCTTCAGCGT TCTGTGGTTGTCAACAGATGCCAGTGAGAGCAGGTGCCAGCAGGGGAAGACACAATTTGGAGTTGGCCTGAGATCTGGGGGAGAAAATCA CCTCTGGCTTCTTGAAGGAACCCCCTCTCTCCAGTCATGTTGGGCTGCCTGCTGCCAGGACTCTGCCTGCCATGTCTTTTGGTGGCTAGA AGGGATGTGCATTCAGGCAGACTGCAGCAGGCCCCAGAGCTGCCGGGCTTTTAGGACACACTCCTCCAATTCCATGCTGGTGTTTTTAAA AAAATTCCAAACTGCAGATGATTTGGGCTTTCTACCTGAAGATGATGTACCACATCTTCTGGGGCTAGGTTGGAACTGGGCATCTTGGAG GCAGAGCCCACCCAGAGCTGCACTCAGACCTGCTGTATCTTCCAGTGACCAGCAGAGCTTAATCAGGAAGCTTCAGAAGAGAGGTAGTCC CAGTGACGTAGTTACACCTATAGTGACACAGCATTCTAAAGTGAATGACTCCAACGAATTAGGTGGTCTGACTACCAGTGGCTCTGCAGA GGTCCACAAGGCGATTACAATTTCCAGTCCCCTAACCACAGACCTGACTGCAGAGCTGTCTGGTGGGCCAAAGAATGTATCAGTGCAACC TGAAATATCAGAGGGTCTTGCTACTACGCCCAGCACTCAACAAGTAAAAAGTTCTGAGAAAACCCAGATTGCTGTCCCCCAGCCAGTGGC TCCCTCCTACAGTTATGCTACCCCTACCCCCCAGGCCTCTTTCCAGAGCACCTCAGCACCATACCCAGTTATAAAGGAACTGGTGGTATC TGCTGGAGAGAGTGTCCAGATAACCCTGCCTAAGAATGAAGTTCAATTAAATGCATATGTTCTCCAAGAACCACCTAAAGGAGAAACCTA CACCTACGACTGGCAGCTGATTACTCATCCTAGAGACTACAGTGGAGAAATGGAAGGGAAACATTCCCAGATCCTCAAACTATCGAAGCT CACTCCAGGCCTGTATGAATTCAAAGTGATTGTAGAGGGTCAAAATGCCCATGGGGAAGGCTATGTGAACGTGACAGTCAAGCCAGAGCC CCGTAAGAATCGGCCCCCCATTGCTATTGTGTCACCTCAGTTCCAGGAGATCTCTTTGCCAACCACTTCTACAGTCATTGATGGCAGTCA AAGCACTGATGATGATAAAATCGTTCAGTACCATTGGGAAGAACTTAAGGGGCCTCTAAGAGAAGAGAAGATTTCTGAAGATACAGCCAT ATTAAAACTAAGTAAACTCGTCCCTGGGAACTACACTTTCAGCTTGACTGTAGTAGACTCTGATGGAGCTACCAACTCTACTACTGCAAA CCTGACAGTGAACAAAGCTGTGGATTACCCCCCTGTGGCCAACGCAGGCCCCAACCAAGTGATCACCCTGCCCCAAAACTCCATCACCCT CTTTGGGAACCAGAGCACTGATGATCATGGCATCACCAGCTATGAGTGGTCACTCAGCCCAAGCAGCAAAGGGAAAGTGGTGGAGATGCA GGGTGTTAGAACACCAACCTTACAGCTCTCTGCGATGCAAGAAGGAGACTACACTTACCAGCTCACAGTGACTGACACAATAGGACAGCA GGCCACTGCTCAAGTGACTGTTATTGTGCAACCTGAAAACAATAAGCCTCCTCAGGCAGATGCAGGCCCAGATAAAGAGCTGACCCTTCC TGTGGATAGCACAACCCTGGATGGCAGCAAGAGCTCAGATGATCAGAAAATTATCTCATATCTCTGGGAAAAAACACAGGGACCTGATGG GGTGCAGCTCGAGAATGCTAACAGCAGTGTTGCTACTGTGACTGGGCTGCAAGTGGGGACCTATGTGTTCACCTTGACTGTCAAAGATGA GAGGAACCTGCAAAGCCAGAGCTCTGTGAATGTCATTGTCAAAGAAGAAATAAACAAACCACCTATAGCCAAGATAACTGGGAATGTGGT GATTACCCTACCCACGAGCACAGCAGAGCTGGATGGCTCTAAGTCCTCAGATGACAAGGGAATAGTCAGCTACCTCTGGACTCGAGATGA GGGGAGCCCAGCAGCAGGGGAGGTGTTAAATCACTCTGACCATCACCCTATCCTTTTTCTTTCAAACCTGGTTGAGGGAACCTACACTTT TCACCTGAAAGTGACCGATGCAAAGGGTGAGAGTGACACAGACCGGACCACTGTGGAGGTGAAACCTGATCCCAGGAAAAACAACCTGGT GGAGATCATCTTGGATATCAACGTCAGTCAGCTAACTGAGAGGCTGAAGGGGATGTTCATCCGCCAGATTGGGGTCCTCCTGGGGGTGCT GGATTCCGACATCATTGTGCAAAAGATTCAGCCGTACACGGAGCAGAGCACCAAAATGGTATTTTTTGTTCAAAACGAGCCTCCCCACCA GATCTTCAAAGGCCATGAGGTGGCAGCGATGCTCAAGAGTGAGCTGCGGAAGCAAAAGGCAGACTTTTTGATATTCAGAGCCTTGGAAGT CAACACTGTCACATGTCAGCTGAACTGTTCCGACCATGGCCACTGTGACTCGTTCACCAAACGCTGTATCTGTGACCCTTTTTGGATGGA GAATTTCATCAAGGTGCAGCTGAGGGATGGAGACAGCAACTGTGAGTGGAGCGTGTTATATGTTATCATTGCTACCTTTGTCATTGTTGT TGCCTTGGGAATCCTGTCTTGGACTGTGATCTGTTGTTGTAAGAGGCTGCCAGGAGATAGCAGAGGAATTCCGTGCCCAGGAAATCGACG GGCAAGCCCTGCTGCTGCTCAAGGAGGACCACCTGATGAGCGCCATGAACATCAAGCTGGGGCCCGCCCTGAAGATCTACGCCCGCATCA GCATGCTCAAGGACTCCTAGGGCTGGTGGCAGCCAGGATTCTGGCCCAGGGCGCCTCCTCCCGACTGAGCAGAGCCAGACAGACATTCCT GAGGGGCCCAGAAATGGGGCCGGTTGGAGGGCAGGGGCTCTCCCTAGGGGCATAGCTGGTGAGGAGGTCTGGGCACCTCCTCCATGGCTC TCAGGGGCCTTTCATTTCTGTGGGAGGGGCAGAGAGGTAGGTGGCACAGAAGATGGGGCTTTATGCTTGTAAATATTGATAGCACTGGCT TCCTCCAAAGTCCCAATACTCTAGCCCCGCTCTCTTCCCCTCTTTCTGTCCCCCATTTTCCAGGGGGTATATGGTCAGGGCTCCCCAACC TGAGTTGGGTTACTTCAAGGGCAGCCAGCAGGCCTGGATGGAGGCCTAGAAAGCCCTTGCCTTCCTTCCTCCCACTTCTTTCTCCAGGCC TGGTTAACTCTTCCGTTGTCAGCTTCTCCCCCTTCAGCCTGTTTCTGCAGCAGCCAGGGTTCTCCCCCCTACACCCTCTGCAGGTGGAGA GAGAGAAGCTGGGCCCAGCCGGGCCGTGCCTGCTGGCACAGACGCCTTAACGCTGTGTGTATGACTGTGTGACTGTGTGGGAGCCTGGAC TGACAGATAGGCCAAGGGCTACTCTCTGGCATCTCCAGGTGTTTTGTAGCAAACAGCCACTTAGTGCTTTGTCCTGGACTCCACTCAGCC TCAGGATGGGGAATAGCCAAGAATGGCAGCCTCAGCGCAGAGGCAAGGTCAGAAAGAGACGGCGCTTCAGAGTTTCCTTTCCAGACACCC CTCCCCGCACTGTGAAGTTCCCCTGACCGCCCTCCTGGTTCACAAAGAGCATTAAGAAAGCTGCGGTGGTCTGAGCAACATAGCCCAAAG GGCTGAGCCTCCTGGCCTGCCTGCCCGCCCACCCTGGGAGTCCCAGTGGTGAGGCTCAGAGAACTGCTAAGGGGAAAGAACAGCTGGAGT TTCTGTTGATGTGAAGAAGGCAGCTCTTGGCCTCCCACTCCCACACTTCTTTGCCTATAAATCTTCCTAGCAGCAATTTGAGCTACCTGA GGAGGAGGCAGGGCAGAAAGGGCGAGGGCCTGCCTCTGACCTGCCGTGTCCTTTGCAGGAAGGAGGTAGGCACCTTTCTGAGCTTATTCT >In-frame_KIAA0319L_ENST00000373266_chr1_35907847_-_PHC2_ENST00000373422_chr1_33790620_-_2702nt TGCTGTGTCAGAGAGGGTTGTTTCCTTGAAGGGGGAAACCCTTAGCAAGGTGCCTCATGATATCTGACTCCATATTCACTCACATGCTGA ACTGGGTGTTAGAACACCAACCTTACAGCTCTCTGCGATGCAAGAAGGAGACTACACTTACCAGCTCACAGTGACTGACACAATAGGACA GCAGGCCACTGCTCAAGTGACTGTTATTGTGCAACCTGAAAACAATAAGCCTCCTCAGGCAGATGCAGGCCCAGATAAAGAGCTGACCCT TCCTGTGGATAGCACAACCCTGGATGGCAGCAAGAGCTCAGATGATCAGAAAATTATCTCATATCTCTGGGAAAAAACACAGGGACCTGA TGGGGTGCAGCTCGAGAATGCTAACAGCAGTGTTGCTACTGTGACTGGGCTGCAAGTGGGGACCTATGTGTTCACCTTGACTGTCAAAGA TGAGAGGAACCTGCAAAGCCAGAGCTCTGTGAATGTCATTGTCAAAGAAGAAATAAACAAACCACCTATAGCCAAGATAACTGGGAATGT GGTGATTACCCTACCCACGAGCACAGCAGAGCTGGATGGCTCTAAGTCCTCAGATGACAAGGGAATAGTCAGCTACCTCTGGACTCGAGA TGAGGGGAGCCCAGCAGCAGGGGAGGTGTTAAATCACTCTGACCATCACCCTATCCTTTTTCTTTCAAACCTGGTTGAGGGAACCTACAC TTTTCACCTGAAAGTGACCGATGCAAAGGGTGAGAGTGACACAGACCGGACCACTGTGGAGGTGAAACCTGATCCCAGGAAAAACAACCT GGTGGAGATCATCTTGGATATCAACGTCAGTCAGCTAACTGAGAGGCTGAAGGGGATGTTCATCCGCCAGATTGGGGTCCTCCTGGGGGT GCTGGATTCCGACATCATTGTGCAAAAGATTCAGCCGTACACGGAGCAGAGCACCAAAATGGTATTTTTTGTTCAAAACGAGCCTCCCCA CCAGATCTTCAAAGGCCATGAGGTGGCAGCGATGCTCAAGAGTGAGCTGCGGAAGCAAAAGGCAGACTTTTTGATATTCAGAGCCTTGGA AGTCAACACTGTCACATGTCAGCTGAACTGTTCCGACCATGGCCACTGTGACTCGTTCACCAAACGCTGTATCTGTGACCCTTTTTGGAT GGAGAATTTCATCAAGGTGCAGCTGAGGGATGGAGACAGCAACTGTGAGTGGAGCGTGTTATATGTTATCATTGCTACCTTTGTCATTGT TGTTGCCTTGGGAATCCTGTCTTGGACTGTGATCTGTTGTTGTAAGAGGCTGCCAGGAGATAGCAGAGGAATTCCGTGCCCAGGAAATCG ACGGGCAAGCCCTGCTGCTGCTCAAGGAGGACCACCTGATGAGCGCCATGAACATCAAGCTGGGGCCCGCCCTGAAGATCTACGCCCGCA TCAGCATGCTCAAGGACTCCTAGGGCTGGTGGCAGCCAGGATTCTGGCCCAGGGCGCCTCCTCCCGACTGAGCAGAGCCAGACAGACATT CCTGAGGGGCCCAGAAATGGGGCCGGTTGGAGGGCAGGGGCTCTCCCTAGGGGCATAGCTGGTGAGGAGGTCTGGGCACCTCCTCCATGG CTCTCAGGGGCCTTTCATTTCTGTGGGAGGGGCAGAGAGGTAGGTGGCACAGAAGATGGGGCTTTATGCTTGTAAATATTGATAGCACTG GCTTCCTCCAAAGTCCCAATACTCTAGCCCCGCTCTCTTCCCCTCTTTCTGTCCCCCATTTTCCAGGGGGTATATGGTCAGGGCTCCCCA ACCTGAGTTGGGTTACTTCAAGGGCAGCCAGCAGGCCTGGATGGAGGCCTAGAAAGCCCTTGCCTTCCTTCCTCCCACTTCTTTCTCCAG GCCTGGTTAACTCTTCCGTTGTCAGCTTCTCCCCCTTCAGCCTGTTTCTGCAGCAGCCAGGGTTCTCCCCCCTACACCCTCTGCAGGTGG AGAGAGAGAAGCTGGGCCCAGCCGGGCCGTGCCTGCTGGCACAGACGCCTTAACGCTGTGTGTATGACTGTGTGACTGTGTGGGAGCCTG GACTGACAGATAGGCCAAGGGCTACTCTCTGGCATCTCCAGGTGTTTTGTAGCAAACAGCCACTTAGTGCTTTGTCCTGGACTCCACTCA GCCTCAGGATGGGGAATAGCCAAGAATGGCAGCCTCAGCGCAGAGGCAAGGTCAGAAAGAGACGGCGCTTCAGAGTTTCCTTTCCAGACA CCCCTCCCCGCACTGTGAAGTTCCCCTGACCGCCCTCCTGGTTCACAAAGAGCATTAAGAAAGCTGCGGTGGTCTGAGCAACATAGCCCA AAGGGCTGAGCCTCCTGGCCTGCCTGCCCGCCCACCCTGGGAGTCCCAGTGGTGAGGCTCAGAGAACTGCTAAGGGGAAAGAACAGCTGG AGTTTCTGTTGATGTGAAGAAGGCAGCTCTTGGCCTCCCACTCCCACACTTCTTTGCCTATAAATCTTCCTAGCAGCAATTTGAGCTACC TGAGGAGGAGGCAGGGCAGAAAGGGCGAGGGCCTGCCTCTGACCTGCCGTGTCCTTTGCAGGAAGGAGGTAGGCACCTTTCTGAGCTTAT TCTATTCCCCACCCACACCCCCAGGCAGGGTTGGAAATGAAGGACTTTTTTAACCTTTGTTTTGTTTTTTAAAAATAAATCTGTAAAATC |
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FusionGenePPI for KIAA0319L_PHC2 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| KIAA0319L | SIAH1, LGALS3, CEACAM21, LGALS8, LGALS9, FCN1, GINM1, MMP3, PILRA, TMEM17, TMEM216, CD4, CCDC40, TMEM30B, MGAT4C, LACRT, LMAN2L, TMPRSS3, LRRTM1, ST8SIA4, PCDHB7, HLA-DRB1, SERPINA12 | PHC2 | MAPKAPK2, FHL3, PHC2, LMO3, MCRS1, SFMBT1, PHC1, BMI1, AFG3L2, BSDC1, RPL7, MCM2, SCMH1, CBX7, PCGF2, RING1, SIAH1, MAPK6, TAB1, MAPK14, RNF2, PHC3, CBX2, CBX4, CBX6, CBX8, SCML1, SCML2, HDAC2, MAPKAPK3, GFI1B, SOX2, PLK1, CSNK2B, CRKL, GRB2, NCK1, HECW2, KDM1A, BYSL, KIFC3, LMO1, LMO2, SMAD3, MFAP1, DRG1, POLR2L, PRKAA1, SDCBP, AP1M1, RBM39, MORF4L2, ZBTB24, RWDD2B, PCGF3, KAT5, PPP1R16B, PRPF31, C1orf109, CARD9, AEN, THAP7, SYT16, KBTBD7, ENKD1, FAM161A, SPATC1L, PCGF5, L3MBTL3, ZGPAT, TRIM41, SSX2IP, MAB21L3, ZNF417, ZMAT2, MAGEB6, FAM124A, FAM13C, FAM74A1, FAM74A4, HIST3H3, EED, CRK, HIST1H2BG, SORT1, SYNCRIP, PCGF1, SFTPC |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for KIAA0319L_PHC2 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for KIAA0319L_PHC2 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
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