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Fusion gene ID: 1857 |
FusionGeneSummary for ANKRD42_RHOD |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: ANKRD42_RHOD | Fusion gene ID: 1857 | Hgene | Tgene | Gene symbol | ANKRD42 | RHOD | Gene ID | 338699 | 29984 |
| Gene name | ankyrin repeat domain 42 | ras homolog family member D | |
| Synonyms | PPP1R79|SARP | ARHD|RHOHP1|RHOM|Rho | |
| Cytomap | 11q14.1 | 11q13.2 | |
| Type of gene | protein-coding | protein-coding | |
| Description | ankyrin repeat domain-containing protein 42protein phosphatase 1, regulatory subunit 79several ankyrin repeat protein | rho-related GTP-binding protein RhoDRho-related protein HP1ras homolog Dras homolog gene family, member Aras homolog gene family, member D | |
| Modification date | 20180519 | 20180523 | |
| UniProtAcc | Q8N9B4 | O00212 | |
| Ensembl transtripts involved in fusion gene | ENST00000528190, ENST00000393389, ENST00000528722, ENST00000260047, ENST00000526731, ENST00000531895, ENST00000393392, ENST00000533342, | ENST00000308831, ENST00000533360, ENST00000532559, | |
| Fusion gene scores | * DoF score | 2 X 2 X 2=8 | 9 X 4 X 8=288 |
| # samples | 2 | 13 | |
| ** MAII score | log2(2/8*10)=1.32192809488736 | log2(13/288*10)=-1.14755718841386 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: ANKRD42 [Title/Abstract] AND RHOD [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | BRCA | TCGA-AN-A0FZ-01A | ANKRD42 | chr11 | 82959129 | + | RHOD | chr11 | 66837896 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 3UTR-3CDS | ENST00000528190 | ENST00000308831 | ANKRD42 | chr11 | 82959129 | + | RHOD | chr11 | 66837896 | + |
| 3UTR-3UTR | ENST00000528190 | ENST00000533360 | ANKRD42 | chr11 | 82959129 | + | RHOD | chr11 | 66837896 | + |
| 3UTR-3UTR | ENST00000528190 | ENST00000532559 | ANKRD42 | chr11 | 82959129 | + | RHOD | chr11 | 66837896 | + |
| intron-3CDS | ENST00000393389 | ENST00000308831 | ANKRD42 | chr11 | 82959129 | + | RHOD | chr11 | 66837896 | + |
| intron-3UTR | ENST00000393389 | ENST00000533360 | ANKRD42 | chr11 | 82959129 | + | RHOD | chr11 | 66837896 | + |
| intron-3UTR | ENST00000393389 | ENST00000532559 | ANKRD42 | chr11 | 82959129 | + | RHOD | chr11 | 66837896 | + |
| intron-3CDS | ENST00000528722 | ENST00000308831 | ANKRD42 | chr11 | 82959129 | + | RHOD | chr11 | 66837896 | + |
| intron-3UTR | ENST00000528722 | ENST00000533360 | ANKRD42 | chr11 | 82959129 | + | RHOD | chr11 | 66837896 | + |
| intron-3UTR | ENST00000528722 | ENST00000532559 | ANKRD42 | chr11 | 82959129 | + | RHOD | chr11 | 66837896 | + |
| In-frame | ENST00000260047 | ENST00000308831 | ANKRD42 | chr11 | 82959129 | + | RHOD | chr11 | 66837896 | + |
| 5CDS-3UTR | ENST00000260047 | ENST00000533360 | ANKRD42 | chr11 | 82959129 | + | RHOD | chr11 | 66837896 | + |
| 5CDS-3UTR | ENST00000260047 | ENST00000532559 | ANKRD42 | chr11 | 82959129 | + | RHOD | chr11 | 66837896 | + |
| intron-3CDS | ENST00000526731 | ENST00000308831 | ANKRD42 | chr11 | 82959129 | + | RHOD | chr11 | 66837896 | + |
| intron-3UTR | ENST00000526731 | ENST00000533360 | ANKRD42 | chr11 | 82959129 | + | RHOD | chr11 | 66837896 | + |
| intron-3UTR | ENST00000526731 | ENST00000532559 | ANKRD42 | chr11 | 82959129 | + | RHOD | chr11 | 66837896 | + |
| In-frame | ENST00000531895 | ENST00000308831 | ANKRD42 | chr11 | 82959129 | + | RHOD | chr11 | 66837896 | + |
| 5CDS-3UTR | ENST00000531895 | ENST00000533360 | ANKRD42 | chr11 | 82959129 | + | RHOD | chr11 | 66837896 | + |
| 5CDS-3UTR | ENST00000531895 | ENST00000532559 | ANKRD42 | chr11 | 82959129 | + | RHOD | chr11 | 66837896 | + |
| 3UTR-3CDS | ENST00000393392 | ENST00000308831 | ANKRD42 | chr11 | 82959129 | + | RHOD | chr11 | 66837896 | + |
| 3UTR-3UTR | ENST00000393392 | ENST00000533360 | ANKRD42 | chr11 | 82959129 | + | RHOD | chr11 | 66837896 | + |
| 3UTR-3UTR | ENST00000393392 | ENST00000532559 | ANKRD42 | chr11 | 82959129 | + | RHOD | chr11 | 66837896 | + |
| In-frame | ENST00000533342 | ENST00000308831 | ANKRD42 | chr11 | 82959129 | + | RHOD | chr11 | 66837896 | + |
| 5CDS-3UTR | ENST00000533342 | ENST00000533360 | ANKRD42 | chr11 | 82959129 | + | RHOD | chr11 | 66837896 | + |
| 5CDS-3UTR | ENST00000533342 | ENST00000532559 | ANKRD42 | chr11 | 82959129 | + | RHOD | chr11 | 66837896 | + |
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FusionProtFeatures for ANKRD42_RHOD |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| ANKRD42 | RHOD |
| Involved in endosome dynamics. May coordinate membranetransport with the function of the cytoskeleton. Involved in theinternalization and trafficking of activated tyrosine kinasereceptors such as PDGFRB. Participates in the reorganization ofactin cytoskeleton; the function seems to involve WHAMM andincludes regulation of filopodia formation and actin filamentbundling. Can modulate the effect of DAPK3 in reorganization ofactin cytoskeleton and focal adhesion dissolution.{ECO:0000269|PubMed:23087206, ECO:0000269|PubMed:23454120,ECO:0000269|PubMed:24102721}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
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FusionGeneSequence for ANKRD42_RHOD |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_ANKRD42_ENST00000260047_chr11_82959129_+_RHOD_ENST00000308831_chr11_66837896_+_589aa MPGVANSGPSTSSRETANPCSRKKVHFGSIHDAVRAGDVKQLSEIVVRGASINELDVLHKFTPLHWAAHSGSLECLHWLLWHGADITHVT TRGWTASHIAAIRGQDACVQALIMNGANLTAQDDRGCTPLHLAATHGHSFTLQIMLRSGDPSVTDKREWRPVHYAAFHGRLGCLQLLVKW GCSIEDVDYNGNLPVHLAAMEGHLHCFKFLVSRMSSATQVLKAFNDNGENVLDLAQRFFKQNILQFIQGAEYEGKDLEDQETLAFPGHVA AFKGDLGMLKKLVEDGVININERADNGSTPMHKAAGQGHIECLQWLIKMGADSNITNKAGERPSDVAKRFAHLAAVKLLEELQKYDIDDE NEIDENDVKYFIRHGVEGSTDAKDDLCLSDLDKTDARMRAYKKIVELRHLLEIAESNYKHLGGITEEDLKQKKEQLESEKTIKELQGQLE YERLRREKLECQLDEYRAEVDQLRETLEKIQVPNFVAMWYPEVNHFCKKVPIIVVGCKTDLCKDKSLVNKLRRNGLEPVTYHRGQEMARS >In-frame_ANKRD42_ENST00000531895_chr11_82959129_+_RHOD_ENST00000308831_chr11_66837896_+_590aa MPGVANSGPSTSSRETANPCSRKKVHFGSIHDAVRAGDVKQLSEIVVRGASINELDVLHKFTPLHWAAHSGSLECLHWLLWHGADITHVT TRGWTASHIAAIRGQDACVQALIMNGANLTAQDDRGCTPLHLAATHGHSFTLQIMLRSGVDPSVTDKREWRPVHYAAFHGRLGCLQLLVK WGCSIEDVDYNGNLPVHLAAMEGHLHCFKFLVSRMSSATQVLKAFNDNGENVLDLAQRFFKQNILQFIQGAEYEGKDLEDQETLAFPGHV AAFKGDLGMLKKLVEDGVININERADNGSTPMHKAAGQGHIECLQWLIKMGADSNITNKAGERPSDVAKRFAHLAAVKLLEELQKYDIDD ENEIDENDVKYFIRHGVEGSTDAKDDLCLSDLDKTDARMRAYKKIVELRHLLEIAESNYKHLGGITEEDLKQKKEQLESEKTIKELQGQL EYERLRREKLECQLDEYRAEVDQLRETLEKIQVPNFVAMWYPEVNHFCKKVPIIVVGCKTDLCKDKSLVNKLRRNGLEPVTYHRGQEMAR >In-frame_ANKRD42_ENST00000533342_chr11_82959129_+_RHOD_ENST00000308831_chr11_66837896_+_742aa MPGVANSGPSTSSRETANPCSRKKVHFGSIHDAVRAGDVKQLSEIVVRGASINELDVLHKFTPLHWAAHSGSLECLHWLLWHGADITHVT TRGWTASHIAAIRGQDACVQALIMNGANLTAQDDRGCTPLHLAATHGHSFTLQIMLRSGVDPSVTDKREWRPVHYAAFHGRLGCLQLLVK WGCSIEDVDYNGNLPVHLAAMEGHLHCFKFLVSRMSSATQVLKAFNDNGENVLDLAQRFFKQNILQFIQGAEYEGKDLEDQETLAFPGHV AAFKGDLGMLKKLVEDGVININERADNGSTPMHKAAGQGHIECLQWLIKMGADSNITNKAGERPSDVAKRFAHLAAVKLLEELQKYDIDD ENEIDENDVKYFIRHGVEGSTDAKDDLCLSDLDKTDARMRAYKKIVELRHLLEIAESNYKHLGGITEEDLKQKKEQLESEKTIKELQGQL EYERLRREKLECQLDEYRAEVDQLRETLEKIQVPNFVAMVGVLFNTFIFLKKYIQEWPRVQALGWGSLDLNPGYSLFXFGLLIXPFCAST INWRXXLILSRADDRIKGIHTHTHTHTHTHTHSICNYNFLDTYTHLSIYLQTAAXFISIIVNIVPXKEKMFSXVINQNSKTARGYVYFNI LNNQNKVLXMEWYPEVNHFCKKVPIIVVGCKTDLCKDKSLVNKLRRNGLEPVTYHRGQEMARSVGAVAYLECSARLHDNVHAVFQEAAEV |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_ANKRD42_ENST00000260047_chr11_82959129_+_RHOD_ENST00000308831_chr11_66837896_+_1767nt ATGCCCGGGGTGGCCAATTCAGGCCCCTCCACTTCCTCTAGGGAGACTGCAAACCCCTGTTCCAGGAAGAAGGTGCATTTTGGCAGCATA CATGATGCAGTACGAGCTGGAGATGTAAAGCAGCTTTCAGAAATAGTGGTACGTGGAGCCAGCATTAATGAACTTGATGTTCTCCATAAG TTTACCCCTTTACATTGGGCAGCACATTCTGGAAGTTTGGAGTGTCTTCATTGGCTGCTCTGGCATGGAGCTGATATCACACACGTAACA ACGAGAGGTTGGACAGCATCTCACATAGCTGCAATCAGGGGTCAGGATGCTTGTGTACAGGCTCTTATAATGAATGGAGCAAATCTGACA GCCCAGGATGACCGGGGATGCACTCCTTTACATCTTGCTGCAACTCATGGACATTCTTTCACTTTACAAATAATGCTCCGAAGTGGAGAT CCCAGTGTGACTGATAAGAGAGAATGGAGACCTGTGCATTATGCAGCTTTTCATGGGCGGCTTGGCTGCTTGCAACTTCTTGTTAAATGG GGTTGTAGCATAGAAGATGTGGACTACAATGGAAACCTTCCAGTTCACTTAGCAGCCATGGAAGGCCACCTTCACTGTTTCAAATTCCTA GTCAGTAGAATGAGCAGTGCGACGCAAGTTTTAAAAGCTTTCAATGATAATGGAGAAAATGTACTGGATTTGGCCCAGAGGTTCTTCAAG CAGAACATTTTACAGTTTATCCAGGGGGCTGAGTATGAAGGAAAAGACCTAGAGGATCAGGAAACTTTAGCATTTCCAGGTCATGTGGCT GCCTTTAAGGGTGATTTGGGGATGCTTAAGAAATTAGTGGAAGATGGAGTAATCAATATTAATGAGCGTGCTGATAATGGATCAACTCCT ATGCATAAAGCTGCTGGACAAGGCCACATAGAGTGTTTGCAGTGGTTAATTAAAATGGGAGCAGACAGTAATATTACCAACAAAGCAGGG GAGAGACCCAGTGATGTGGCAAAGAGGTTTGCCCATTTGGCAGCAGTGAAGCTGTTAGAGGAGCTACAGAAATATGATATAGATGACGAA AATGAAATTGATGAAAATGATGTGAAATATTTTATAAGACATGGTGTTGAGGGAAGCACTGATGCCAAGGATGATTTATGTCTGAGTGAC TTGGATAAAACAGATGCCAGAATGAGAGCTTACAAGAAAATTGTAGAATTGAGACACCTCCTGGAAATTGCCGAGAGCAACTATAAACAC TTGGGAGGCATAACAGAAGAAGATTTAAAGCAGAAGAAAGAACAGCTTGAGTCTGAAAAGACCATCAAAGAACTGCAGGGCCAGCTGGAG TATGAACGACTACGTAGAGAAAAATTAGAATGTCAGCTTGATGAATATCGAGCAGAAGTTGATCAACTCAGGGAAACACTGGAAAAAATT CAAGTCCCAAACTTTGTGGCTATGTGGTACCCAGAAGTGAATCATTTCTGCAAGAAGGTACCCATCATCGTCGTGGGCTGCAAGACTGAC CTGTGCAAGGACAAATCACTGGTGAACAAGCTCCGAAGAAACGGATTGGAGCCTGTGACCTACCACAGGGGCCAGGAGATGGCGAGGTCC GTGGGCGCGGTGGCCTACCTCGAGTGCTCGGCTCGGCTCCATGACAACGTCCACGCCGTCTTCCAGGAGGCCGCCGAGGTGGCCCTCAGC >In-frame_ANKRD42_ENST00000531895_chr11_82959129_+_RHOD_ENST00000308831_chr11_66837896_+_1770nt ATGCCCGGGGTGGCCAATTCAGGCCCCTCCACTTCCTCTAGGGAGACTGCAAACCCCTGTTCCAGGAAGAAGGTGCATTTTGGCAGCATA CATGATGCAGTACGAGCTGGAGATGTAAAGCAGCTTTCAGAAATAGTGGTACGTGGAGCCAGCATTAATGAACTTGATGTTCTCCATAAG TTTACCCCTTTACATTGGGCAGCACATTCTGGAAGTTTGGAGTGTCTTCATTGGCTGCTCTGGCATGGAGCTGATATCACACACGTAACA ACGAGAGGTTGGACAGCATCTCACATAGCTGCAATCAGGGGTCAGGATGCTTGTGTACAGGCTCTTATAATGAATGGAGCAAATCTGACA GCCCAGGATGACCGGGGATGCACTCCTTTACATCTTGCTGCAACTCATGGACATTCTTTCACTTTACAAATAATGCTCCGAAGTGGAGTG GATCCCAGTGTGACTGATAAGAGAGAATGGAGACCTGTGCATTATGCAGCTTTTCATGGGCGGCTTGGCTGCTTGCAACTTCTTGTTAAA TGGGGTTGTAGCATAGAAGATGTGGACTACAATGGAAACCTTCCAGTTCACTTAGCAGCCATGGAAGGCCACCTTCACTGTTTCAAATTC CTAGTCAGTAGAATGAGCAGTGCGACGCAAGTTTTAAAAGCTTTCAATGATAATGGAGAAAATGTACTGGATTTGGCCCAGAGGTTCTTC AAGCAGAACATTTTACAGTTTATCCAGGGGGCTGAGTATGAAGGAAAAGACCTAGAGGATCAGGAAACTTTAGCATTTCCAGGTCATGTG GCTGCCTTTAAGGGTGATTTGGGGATGCTTAAGAAATTAGTGGAAGATGGAGTAATCAATATTAATGAGCGTGCTGATAATGGATCAACT CCTATGCATAAAGCTGCTGGACAAGGCCACATAGAGTGTTTGCAGTGGTTAATTAAAATGGGAGCAGACAGTAATATTACCAACAAAGCA GGGGAGAGACCCAGTGATGTGGCAAAGAGGTTTGCCCATTTGGCAGCAGTGAAGCTGTTAGAGGAGCTACAGAAATATGATATAGATGAC GAAAATGAAATTGATGAAAATGATGTGAAATATTTTATAAGACATGGTGTTGAGGGAAGCACTGATGCCAAGGATGATTTATGTCTGAGT GACTTGGATAAAACAGATGCCAGAATGAGAGCTTACAAGAAAATTGTAGAATTGAGACACCTCCTGGAAATTGCCGAGAGCAACTATAAA CACTTGGGAGGCATAACAGAAGAAGATTTAAAGCAGAAGAAAGAACAGCTTGAGTCTGAAAAGACCATCAAAGAACTGCAGGGCCAGCTG GAGTATGAACGACTACGTAGAGAAAAATTAGAATGTCAGCTTGATGAATATCGAGCAGAAGTTGATCAACTCAGGGAAACACTGGAAAAA ATTCAAGTCCCAAACTTTGTGGCTATGTGGTACCCAGAAGTGAATCATTTCTGCAAGAAGGTACCCATCATCGTCGTGGGCTGCAAGACT GACCTGTGCAAGGACAAATCACTGGTGAACAAGCTCCGAAGAAACGGATTGGAGCCTGTGACCTACCACAGGGGCCAGGAGATGGCGAGG TCCGTGGGCGCGGTGGCCTACCTCGAGTGCTCGGCTCGGCTCCATGACAACGTCCACGCCGTCTTCCAGGAGGCCGCCGAGGTGGCCCTC >In-frame_ANKRD42_ENST00000533342_chr11_82959129_+_RHOD_ENST00000308831_chr11_66837896_+_2226nt ATGCCCGGGGTGGCCAATTCAGGCCCCTCCACTTCCTCTAGGGAGACTGCAAACCCCTGTTCCAGGAAGAAGGTGCATTTTGGCAGCATA CATGATGCAGTACGAGCTGGAGATGTAAAGCAGCTTTCAGAAATAGTGGTACGTGGAGCCAGCATTAATGAACTTGATGTTCTCCATAAG TTTACCCCTTTACATTGGGCAGCACATTCTGGAAGTTTGGAGTGTCTTCATTGGCTGCTCTGGCATGGAGCTGATATCACACACGTAACA ACGAGAGGTTGGACAGCATCTCACATAGCTGCAATCAGGGGTCAGGATGCTTGTGTACAGGCTCTTATAATGAATGGAGCAAATCTGACA GCCCAGGATGACCGGGGATGCACTCCTTTACATCTTGCTGCAACTCATGGACATTCTTTCACTTTACAAATAATGCTCCGAAGTGGAGTG GATCCCAGTGTGACTGATAAGAGAGAATGGAGACCTGTGCATTATGCAGCTTTTCATGGGCGGCTTGGCTGCTTGCAACTTCTTGTTAAA TGGGGTTGTAGCATAGAAGATGTGGACTACAATGGAAACCTTCCAGTTCACTTAGCAGCCATGGAAGGCCACCTTCACTGTTTCAAATTC CTAGTCAGTAGAATGAGCAGTGCGACGCAAGTTTTAAAAGCTTTCAATGATAATGGAGAAAATGTACTGGATTTGGCCCAGAGGTTCTTC AAGCAGAACATTTTACAGTTTATCCAGGGGGCTGAGTATGAAGGAAAAGACCTAGAGGATCAGGAAACTTTAGCATTTCCAGGTCATGTG GCTGCCTTTAAGGGTGATTTGGGGATGCTTAAGAAATTAGTGGAAGATGGAGTAATCAATATTAATGAGCGTGCTGATAATGGATCAACT CCTATGCATAAAGCTGCTGGACAAGGCCACATAGAGTGTTTGCAGTGGTTAATTAAAATGGGAGCAGACAGTAATATTACCAACAAAGCA GGGGAGAGACCCAGTGATGTGGCAAAGAGGTTTGCCCATTTGGCAGCAGTGAAGCTGTTAGAGGAGCTACAGAAATATGATATAGATGAC GAAAATGAAATTGATGAAAATGATGTGAAATATTTTATAAGACATGGTGTTGAGGGAAGCACTGATGCCAAGGATGATTTATGTCTGAGT GACTTGGATAAAACAGATGCCAGAATGAGAGCTTACAAGAAAATTGTAGAATTGAGACACCTCCTGGAAATTGCCGAGAGCAACTATAAA CACTTGGGAGGCATAACAGAAGAAGATTTAAAGCAGAAGAAAGAACAGCTTGAGTCTGAAAAGACCATCAAAGAACTGCAGGGCCAGCTG GAGTATGAACGACTACGTAGAGAAAAATTAGAATGTCAGCTTGATGAATATCGAGCAGAAGTTGATCAACTCAGGGAAACACTGGAAAAA ATTCAAGTCCCAAACTTTGTGGCTATGGTTGGTGTCCTTTTTAATACATTTATTTTTCTCAAGAAGTATATACAAGAGTGGCCAAGAGTA CAAGCTTTGGGCTGGGGCTCTTTGGACTTGAATCCTGGCTATAGTCTTTTTTGATTTGGGCTACTCATTTAACCTTTTTGTGCCTCAACT ATAAACTGGAGATGATAACTTATACTTTCTAGAGCTGATGACAGGATTAAAGGAATACACACACACACACACACACACACACACACACAC ACACACTCTATATGTAACTATAACTTTCTAGATACATACACACATCTGTCTATCTATCTTCAAACAGCAGCCTAGTTCATAAGTATTATT GTTAACATTGTACCATAGAAGGAGAAAATGTTTTCATAAGTAATCAATCAGAATTCTAAGACAGCTAGAGGATATGTATATTTTAATATT CTAAATAACCAAAATAAAGTGCTTTGAATGGAATGGTACCCAGAAGTGAATCATTTCTGCAAGAAGGTACCCATCATCGTCGTGGGCTGC AAGACTGACCTGTGCAAGGACAAATCACTGGTGAACAAGCTCCGAAGAAACGGATTGGAGCCTGTGACCTACCACAGGGGCCAGGAGATG GCGAGGTCCGTGGGCGCGGTGGCCTACCTCGAGTGCTCGGCTCGGCTCCATGACAACGTCCACGCCGTCTTCCAGGAGGCCGCCGAGGTG |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_ANKRD42_ENST00000260047_chr11_82959129_+_RHOD_ENST00000308831_chr11_66837896_+_2973nt TGGAGGATAAACGGTCTACACGGCCATTCCGGCGCCGAGTCTAGGGAAAGAGTTAGCGACGACGGGGAAAGAAAATGTGAAGAGAGCGAC CGCCGCTCCAGGGTCGCTGCAGGAAGCCTAAGTGCAGACGCCGGCTTCTCCCGCAGTGACTTGAGAAGGGTCAGTGAAAACCTCGGCCAC TGCCGCAGCGTCTCTAGGGAGAGAGTTAGGGGAGATAGTGGCCACAGTCACAGCTGCTCTTGGGAGAGAGTTAGGGGAGACAGCACCTTC TGCAGCAGCGACGTGAATTTTAGTGAAGTTGGAGGCCACCAAACTACCGACTCCAGGGGAACAGCCAGAGAAGACCGAGGCCTCCGCCTC AGTGGTCCTTGGGAGGGAGTCAGTGACATTCGGGACCCGCGAACTAGTGACTTCGGGGATAGAGTCAGTGACGATCGCAGTCGCCGCTTC AGTGGCTCCTGGGAGGGAGGGAGTGTCGAAGGCGGCCACAGCGTTGGTAGTTCTTGGGAGGAAGTAAGTGGAGACCGCGGCTACGCAGCC AGCGACTCCTCTGGTGTGAGCGGCAGTGAAGACGCCAGCTACCGCTTCAGTGGCTTTTGGGAGAGAGAAAGTGAAGACGAAGGTTTCCGC TGCAGCTTCTGGGAGAGAGCAAGAGAGGACCTTGGGCCCCGTCCTAGTGACGACGGAGAAGAGGGCCGCTGCCGCTGCAGTGGCTCGTGG GTGAGAGCAAGTGAAGACCGCCGCAGCATCAGGGGCCTGGACTCAACTCCTCCCCAGAGTCGGAGGTGTTGCGCCATGCCCGGGGTGGCC AATTCAGGCCCCTCCACTTCCTCTAGGGAGACTGCAAACCCCTGTTCCAGGAAGAAGGTGCATTTTGGCAGCATACATGATGCAGTACGA GCTGGAGATGTAAAGCAGCTTTCAGAAATAGTGGTACGTGGAGCCAGCATTAATGAACTTGATGTTCTCCATAAGTTTACCCCTTTACAT TGGGCAGCACATTCTGGAAGTTTGGAGTGTCTTCATTGGCTGCTCTGGCATGGAGCTGATATCACACACGTAACAACGAGAGGTTGGACA GCATCTCACATAGCTGCAATCAGGGGTCAGGATGCTTGTGTACAGGCTCTTATAATGAATGGAGCAAATCTGACAGCCCAGGATGACCGG GGATGCACTCCTTTACATCTTGCTGCAACTCATGGACATTCTTTCACTTTACAAATAATGCTCCGAAGTGGAGATCCCAGTGTGACTGAT AAGAGAGAATGGAGACCTGTGCATTATGCAGCTTTTCATGGGCGGCTTGGCTGCTTGCAACTTCTTGTTAAATGGGGTTGTAGCATAGAA GATGTGGACTACAATGGAAACCTTCCAGTTCACTTAGCAGCCATGGAAGGCCACCTTCACTGTTTCAAATTCCTAGTCAGTAGAATGAGC AGTGCGACGCAAGTTTTAAAAGCTTTCAATGATAATGGAGAAAATGTACTGGATTTGGCCCAGAGGTTCTTCAAGCAGAACATTTTACAG TTTATCCAGGGGGCTGAGTATGAAGGAAAAGACCTAGAGGATCAGGAAACTTTAGCATTTCCAGGTCATGTGGCTGCCTTTAAGGGTGAT TTGGGGATGCTTAAGAAATTAGTGGAAGATGGAGTAATCAATATTAATGAGCGTGCTGATAATGGATCAACTCCTATGCATAAAGCTGCT GGACAAGGCCACATAGAGTGTTTGCAGTGGTTAATTAAAATGGGAGCAGACAGTAATATTACCAACAAAGCAGGGGAGAGACCCAGTGAT GTGGCAAAGAGGTTTGCCCATTTGGCAGCAGTGAAGCTGTTAGAGGAGCTACAGAAATATGATATAGATGACGAAAATGAAATTGATGAA AATGATGTGAAATATTTTATAAGACATGGTGTTGAGGGAAGCACTGATGCCAAGGATGATTTATGTCTGAGTGACTTGGATAAAACAGAT GCCAGAATGAGAGCTTACAAGAAAATTGTAGAATTGAGACACCTCCTGGAAATTGCCGAGAGCAACTATAAACACTTGGGAGGCATAACA GAAGAAGATTTAAAGCAGAAGAAAGAACAGCTTGAGTCTGAAAAGACCATCAAAGAACTGCAGGGCCAGCTGGAGTATGAACGACTACGT AGAGAAAAATTAGAATGTCAGCTTGATGAATATCGAGCAGAAGTTGATCAACTCAGGGAAACACTGGAAAAAATTCAAGTCCCAAACTTT GTGGCTATGTGGTACCCAGAAGTGAATCATTTCTGCAAGAAGGTACCCATCATCGTCGTGGGCTGCAAGACTGACCTGTGCAAGGACAAA TCACTGGTGAACAAGCTCCGAAGAAACGGATTGGAGCCTGTGACCTACCACAGGGGCCAGGAGATGGCGAGGTCCGTGGGCGCGGTGGCC TACCTCGAGTGCTCGGCTCGGCTCCATGACAACGTCCACGCCGTCTTCCAGGAGGCCGCCGAGGTGGCCCTCAGCAGCCGCGGTCGCAAC TTCTGGCGGCGGATTACCCAGGGCTTTTGCGTGGTGACCTGAGCGGCTCGGGGCGTCCCAGCGACGCGGGAAGGGGCAGGGCGCTGACCT GCTGCTGAGCTGGCTGGGCTGGACCCGGTCCCTAGGCTGTGACCGCCGAACTCCACTGCAACAGACGGGCGCCACCAAAGCCAGGCCCTG AGGCCTGGGAGTCCTGGACTGAGAAAGGGGGTTCCTGGGCCCACCTGCTCTGTGTAGGGCTCGTCCTGCGGTGCCCGAGAATCACTCGCT AACCCCTATGCCCGGTCCCGGACCGACATCCTGGAGCCGCCTGTGCAGCCTGATGCCCCCTCGTGGCTGCTCCCAGGGCTGCACCTGCCA GGACCTAATGTTCTTAGGTCCCTCTGGCCAGAACCCACACCCGGCCCCTTCCCACCTGTCATACTGGTAACTGTAACAAGAAAAACGACA >In-frame_ANKRD42_ENST00000531895_chr11_82959129_+_RHOD_ENST00000308831_chr11_66837896_+_2454nt GACCGCGGCTACGCAGCCAGCGACTCCTCTGGTGTGAGCGGCAGTGAAGACGCCAGCTACCGCTTCAGTGGCTTTTGGGAGAGAGAAAGT GAAGACGAAGGTTTCCGCTGCAGCTTCTGGGAGAGAGCAAGAGAGGACCTTGGGCCCCGTCCTAGTGACGACGGAGAAGAGGGCCGCTGC CGCTGCAGTGGCTCGTGGGTGAGAGCAAGTGAAGACCGCCGCAGCATCAGGGGCCTGGACTCAACTCCTCCCCAGAGTCGGAGGTGTTGC GCCATGCCCGGGGTGGCCAATTCAGGCCCCTCCACTTCCTCTAGGGAGACTGCAAACCCCTGTTCCAGGAAGAAGGTGCATTTTGGCAGC ATACATGATGCAGTACGAGCTGGAGATGTAAAGCAGCTTTCAGAAATAGTGGTACGTGGAGCCAGCATTAATGAACTTGATGTTCTCCAT AAGTTTACCCCTTTACATTGGGCAGCACATTCTGGAAGTTTGGAGTGTCTTCATTGGCTGCTCTGGCATGGAGCTGATATCACACACGTA ACAACGAGAGGTTGGACAGCATCTCACATAGCTGCAATCAGGGGTCAGGATGCTTGTGTACAGGCTCTTATAATGAATGGAGCAAATCTG ACAGCCCAGGATGACCGGGGATGCACTCCTTTACATCTTGCTGCAACTCATGGACATTCTTTCACTTTACAAATAATGCTCCGAAGTGGA GTGGATCCCAGTGTGACTGATAAGAGAGAATGGAGACCTGTGCATTATGCAGCTTTTCATGGGCGGCTTGGCTGCTTGCAACTTCTTGTT AAATGGGGTTGTAGCATAGAAGATGTGGACTACAATGGAAACCTTCCAGTTCACTTAGCAGCCATGGAAGGCCACCTTCACTGTTTCAAA TTCCTAGTCAGTAGAATGAGCAGTGCGACGCAAGTTTTAAAAGCTTTCAATGATAATGGAGAAAATGTACTGGATTTGGCCCAGAGGTTC TTCAAGCAGAACATTTTACAGTTTATCCAGGGGGCTGAGTATGAAGGAAAAGACCTAGAGGATCAGGAAACTTTAGCATTTCCAGGTCAT GTGGCTGCCTTTAAGGGTGATTTGGGGATGCTTAAGAAATTAGTGGAAGATGGAGTAATCAATATTAATGAGCGTGCTGATAATGGATCA ACTCCTATGCATAAAGCTGCTGGACAAGGCCACATAGAGTGTTTGCAGTGGTTAATTAAAATGGGAGCAGACAGTAATATTACCAACAAA GCAGGGGAGAGACCCAGTGATGTGGCAAAGAGGTTTGCCCATTTGGCAGCAGTGAAGCTGTTAGAGGAGCTACAGAAATATGATATAGAT GACGAAAATGAAATTGATGAAAATGATGTGAAATATTTTATAAGACATGGTGTTGAGGGAAGCACTGATGCCAAGGATGATTTATGTCTG AGTGACTTGGATAAAACAGATGCCAGAATGAGAGCTTACAAGAAAATTGTAGAATTGAGACACCTCCTGGAAATTGCCGAGAGCAACTAT AAACACTTGGGAGGCATAACAGAAGAAGATTTAAAGCAGAAGAAAGAACAGCTTGAGTCTGAAAAGACCATCAAAGAACTGCAGGGCCAG CTGGAGTATGAACGACTACGTAGAGAAAAATTAGAATGTCAGCTTGATGAATATCGAGCAGAAGTTGATCAACTCAGGGAAACACTGGAA AAAATTCAAGTCCCAAACTTTGTGGCTATGTGGTACCCAGAAGTGAATCATTTCTGCAAGAAGGTACCCATCATCGTCGTGGGCTGCAAG ACTGACCTGTGCAAGGACAAATCACTGGTGAACAAGCTCCGAAGAAACGGATTGGAGCCTGTGACCTACCACAGGGGCCAGGAGATGGCG AGGTCCGTGGGCGCGGTGGCCTACCTCGAGTGCTCGGCTCGGCTCCATGACAACGTCCACGCCGTCTTCCAGGAGGCCGCCGAGGTGGCC CTCAGCAGCCGCGGTCGCAACTTCTGGCGGCGGATTACCCAGGGCTTTTGCGTGGTGACCTGAGCGGCTCGGGGCGTCCCAGCGACGCGG GAAGGGGCAGGGCGCTGACCTGCTGCTGAGCTGGCTGGGCTGGACCCGGTCCCTAGGCTGTGACCGCCGAACTCCACTGCAACAGACGGG CGCCACCAAAGCCAGGCCCTGAGGCCTGGGAGTCCTGGACTGAGAAAGGGGGTTCCTGGGCCCACCTGCTCTGTGTAGGGCTCGTCCTGC GGTGCCCGAGAATCACTCGCTAACCCCTATGCCCGGTCCCGGACCGACATCCTGGAGCCGCCTGTGCAGCCTGATGCCCCCTCGTGGCTG CTCCCAGGGCTGCACCTGCCAGGACCTAATGTTCTTAGGTCCCTCTGGCCAGAACCCACACCCGGCCCCTTCCCACCTGTCATACTGGTA >In-frame_ANKRD42_ENST00000533342_chr11_82959129_+_RHOD_ENST00000308831_chr11_66837896_+_2910nt GACCGCGGCTACGCAGCCAGCGACTCCTCTGGTGTGAGCGGCAGTGAAGACGCCAGCTACCGCTTCAGTGGCTTTTGGGAGAGAGAAAGT GAAGACGAAGGTTTCCGCTGCAGCTTCTGGGAGAGAGCAAGAGAGGACCTTGGGCCCCGTCCTAGTGACGACGGAGAAGAGGGCCGCTGC CGCTGCAGTGGCTCGTGGGTGAGAGCAAGTGAAGACCGCCGCAGCATCAGGGGCCTGGACTCAACTCCTCCCCAGAGTCGGAGGTGTTGC GCCATGCCCGGGGTGGCCAATTCAGGCCCCTCCACTTCCTCTAGGGAGACTGCAAACCCCTGTTCCAGGAAGAAGGTGCATTTTGGCAGC ATACATGATGCAGTACGAGCTGGAGATGTAAAGCAGCTTTCAGAAATAGTGGTACGTGGAGCCAGCATTAATGAACTTGATGTTCTCCAT AAGTTTACCCCTTTACATTGGGCAGCACATTCTGGAAGTTTGGAGTGTCTTCATTGGCTGCTCTGGCATGGAGCTGATATCACACACGTA ACAACGAGAGGTTGGACAGCATCTCACATAGCTGCAATCAGGGGTCAGGATGCTTGTGTACAGGCTCTTATAATGAATGGAGCAAATCTG ACAGCCCAGGATGACCGGGGATGCACTCCTTTACATCTTGCTGCAACTCATGGACATTCTTTCACTTTACAAATAATGCTCCGAAGTGGA GTGGATCCCAGTGTGACTGATAAGAGAGAATGGAGACCTGTGCATTATGCAGCTTTTCATGGGCGGCTTGGCTGCTTGCAACTTCTTGTT AAATGGGGTTGTAGCATAGAAGATGTGGACTACAATGGAAACCTTCCAGTTCACTTAGCAGCCATGGAAGGCCACCTTCACTGTTTCAAA TTCCTAGTCAGTAGAATGAGCAGTGCGACGCAAGTTTTAAAAGCTTTCAATGATAATGGAGAAAATGTACTGGATTTGGCCCAGAGGTTC TTCAAGCAGAACATTTTACAGTTTATCCAGGGGGCTGAGTATGAAGGAAAAGACCTAGAGGATCAGGAAACTTTAGCATTTCCAGGTCAT GTGGCTGCCTTTAAGGGTGATTTGGGGATGCTTAAGAAATTAGTGGAAGATGGAGTAATCAATATTAATGAGCGTGCTGATAATGGATCA ACTCCTATGCATAAAGCTGCTGGACAAGGCCACATAGAGTGTTTGCAGTGGTTAATTAAAATGGGAGCAGACAGTAATATTACCAACAAA GCAGGGGAGAGACCCAGTGATGTGGCAAAGAGGTTTGCCCATTTGGCAGCAGTGAAGCTGTTAGAGGAGCTACAGAAATATGATATAGAT GACGAAAATGAAATTGATGAAAATGATGTGAAATATTTTATAAGACATGGTGTTGAGGGAAGCACTGATGCCAAGGATGATTTATGTCTG AGTGACTTGGATAAAACAGATGCCAGAATGAGAGCTTACAAGAAAATTGTAGAATTGAGACACCTCCTGGAAATTGCCGAGAGCAACTAT AAACACTTGGGAGGCATAACAGAAGAAGATTTAAAGCAGAAGAAAGAACAGCTTGAGTCTGAAAAGACCATCAAAGAACTGCAGGGCCAG CTGGAGTATGAACGACTACGTAGAGAAAAATTAGAATGTCAGCTTGATGAATATCGAGCAGAAGTTGATCAACTCAGGGAAACACTGGAA AAAATTCAAGTCCCAAACTTTGTGGCTATGGTTGGTGTCCTTTTTAATACATTTATTTTTCTCAAGAAGTATATACAAGAGTGGCCAAGA GTACAAGCTTTGGGCTGGGGCTCTTTGGACTTGAATCCTGGCTATAGTCTTTTTTGATTTGGGCTACTCATTTAACCTTTTTGTGCCTCA ACTATAAACTGGAGATGATAACTTATACTTTCTAGAGCTGATGACAGGATTAAAGGAATACACACACACACACACACACACACACACACA CACACACACTCTATATGTAACTATAACTTTCTAGATACATACACACATCTGTCTATCTATCTTCAAACAGCAGCCTAGTTCATAAGTATT ATTGTTAACATTGTACCATAGAAGGAGAAAATGTTTTCATAAGTAATCAATCAGAATTCTAAGACAGCTAGAGGATATGTATATTTTAAT ATTCTAAATAACCAAAATAAAGTGCTTTGAATGGAATGGTACCCAGAAGTGAATCATTTCTGCAAGAAGGTACCCATCATCGTCGTGGGC TGCAAGACTGACCTGTGCAAGGACAAATCACTGGTGAACAAGCTCCGAAGAAACGGATTGGAGCCTGTGACCTACCACAGGGGCCAGGAG ATGGCGAGGTCCGTGGGCGCGGTGGCCTACCTCGAGTGCTCGGCTCGGCTCCATGACAACGTCCACGCCGTCTTCCAGGAGGCCGCCGAG GTGGCCCTCAGCAGCCGCGGTCGCAACTTCTGGCGGCGGATTACCCAGGGCTTTTGCGTGGTGACCTGAGCGGCTCGGGGCGTCCCAGCG ACGCGGGAAGGGGCAGGGCGCTGACCTGCTGCTGAGCTGGCTGGGCTGGACCCGGTCCCTAGGCTGTGACCGCCGAACTCCACTGCAACA GACGGGCGCCACCAAAGCCAGGCCCTGAGGCCTGGGAGTCCTGGACTGAGAAAGGGGGTTCCTGGGCCCACCTGCTCTGTGTAGGGCTCG TCCTGCGGTGCCCGAGAATCACTCGCTAACCCCTATGCCCGGTCCCGGACCGACATCCTGGAGCCGCCTGTGCAGCCTGATGCCCCCTCG TGGCTGCTCCCAGGGCTGCACCTGCCAGGACCTAATGTTCTTAGGTCCCTCTGGCCAGAACCCACACCCGGCCCCTTCCCACCTGTCATA |
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FusionGenePPI for ANKRD42_RHOD |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| ANKRD42 | PPP1CC | RHOD | DIAPH2, PLXNA1, IHH, ADCK5, ADRB2, ANKFY1, SPTB, PLXNB2, DAAM1, TTC19, CETN3, TRMT61B, DIAPH1, PCBP3, C1orf198, TRIM25 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for ANKRD42_RHOD |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for ANKRD42_RHOD |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
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