|
||||||
|
 | |
| |
| |
| |
| |
|
Fusion gene ID: 18568 |
FusionGeneSummary for KIAA0232_INPP4B |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: KIAA0232_INPP4B | Fusion gene ID: 18568 | Hgene | Tgene | Gene symbol | KIAA0232 | INPP4B | Gene ID | 9778 | 8821 |
| Gene name | KIAA0232 | inositol polyphosphate-4-phosphatase type II B | |
| Synonyms | - | - | |
| Cytomap | 4p16.1 | 4q31.21 | |
| Type of gene | protein-coding | protein-coding | |
| Description | uncharacterized protein KIAA0232 | type II inositol 3,4-bisphosphate 4-phosphataseinositol polyphosphate 4-phosphatase II; 4-phosphatase IIinositol polyphosphate-4-phosphatase, type II, 105kDa | |
| Modification date | 20180519 | 20180523 | |
| UniProtAcc | Q92628 | O15327 | |
| Ensembl transtripts involved in fusion gene | ENST00000503278, ENST00000425103, ENST00000307659, | ENST00000513000, ENST00000509777, ENST00000262992, ENST00000308502, ENST00000508116, ENST00000507861, ENST00000506217, ENST00000508084, | |
| Fusion gene scores | * DoF score | 8 X 7 X 4=224 | 9 X 7 X 6=378 |
| # samples | 8 | 9 | |
| ** MAII score | log2(8/224*10)=-1.48542682717024 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(9/378*10)=-2.0703893278914 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: KIAA0232 [Title/Abstract] AND INPP4B [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | BRCA | TCGA-LL-A441-01A | KIAA0232 | chr4 | 6826411 | + | INPP4B | chr4 | 142950067 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| intron-3CDS | ENST00000503278 | ENST00000513000 | KIAA0232 | chr4 | 6826411 | + | INPP4B | chr4 | 142950067 | - |
| intron-intron | ENST00000503278 | ENST00000509777 | KIAA0232 | chr4 | 6826411 | + | INPP4B | chr4 | 142950067 | - |
| intron-intron | ENST00000503278 | ENST00000262992 | KIAA0232 | chr4 | 6826411 | + | INPP4B | chr4 | 142950067 | - |
| intron-intron | ENST00000503278 | ENST00000308502 | KIAA0232 | chr4 | 6826411 | + | INPP4B | chr4 | 142950067 | - |
| intron-intron | ENST00000503278 | ENST00000508116 | KIAA0232 | chr4 | 6826411 | + | INPP4B | chr4 | 142950067 | - |
| intron-intron | ENST00000503278 | ENST00000507861 | KIAA0232 | chr4 | 6826411 | + | INPP4B | chr4 | 142950067 | - |
| intron-intron | ENST00000503278 | ENST00000506217 | KIAA0232 | chr4 | 6826411 | + | INPP4B | chr4 | 142950067 | - |
| intron-intron | ENST00000503278 | ENST00000508084 | KIAA0232 | chr4 | 6826411 | + | INPP4B | chr4 | 142950067 | - |
| In-frame | ENST00000425103 | ENST00000513000 | KIAA0232 | chr4 | 6826411 | + | INPP4B | chr4 | 142950067 | - |
| 5CDS-intron | ENST00000425103 | ENST00000509777 | KIAA0232 | chr4 | 6826411 | + | INPP4B | chr4 | 142950067 | - |
| 5CDS-intron | ENST00000425103 | ENST00000262992 | KIAA0232 | chr4 | 6826411 | + | INPP4B | chr4 | 142950067 | - |
| 5CDS-intron | ENST00000425103 | ENST00000308502 | KIAA0232 | chr4 | 6826411 | + | INPP4B | chr4 | 142950067 | - |
| 5CDS-intron | ENST00000425103 | ENST00000508116 | KIAA0232 | chr4 | 6826411 | + | INPP4B | chr4 | 142950067 | - |
| 5CDS-intron | ENST00000425103 | ENST00000507861 | KIAA0232 | chr4 | 6826411 | + | INPP4B | chr4 | 142950067 | - |
| 5CDS-intron | ENST00000425103 | ENST00000506217 | KIAA0232 | chr4 | 6826411 | + | INPP4B | chr4 | 142950067 | - |
| 5CDS-intron | ENST00000425103 | ENST00000508084 | KIAA0232 | chr4 | 6826411 | + | INPP4B | chr4 | 142950067 | - |
| In-frame | ENST00000307659 | ENST00000513000 | KIAA0232 | chr4 | 6826411 | + | INPP4B | chr4 | 142950067 | - |
| 5CDS-intron | ENST00000307659 | ENST00000509777 | KIAA0232 | chr4 | 6826411 | + | INPP4B | chr4 | 142950067 | - |
| 5CDS-intron | ENST00000307659 | ENST00000262992 | KIAA0232 | chr4 | 6826411 | + | INPP4B | chr4 | 142950067 | - |
| 5CDS-intron | ENST00000307659 | ENST00000308502 | KIAA0232 | chr4 | 6826411 | + | INPP4B | chr4 | 142950067 | - |
| 5CDS-intron | ENST00000307659 | ENST00000508116 | KIAA0232 | chr4 | 6826411 | + | INPP4B | chr4 | 142950067 | - |
| 5CDS-intron | ENST00000307659 | ENST00000507861 | KIAA0232 | chr4 | 6826411 | + | INPP4B | chr4 | 142950067 | - |
| 5CDS-intron | ENST00000307659 | ENST00000506217 | KIAA0232 | chr4 | 6826411 | + | INPP4B | chr4 | 142950067 | - |
| 5CDS-intron | ENST00000307659 | ENST00000508084 | KIAA0232 | chr4 | 6826411 | + | INPP4B | chr4 | 142950067 | - |
Top |
FusionProtFeatures for KIAA0232_INPP4B |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| KIAA0232 | INPP4B |
| Catalyzes the hydrolysis of the 4-position phosphate ofphosphatidylinositol 3,4-bisphosphate, inositol 1,3,4-trisphosphate and inositol 1,4-bisphosphate. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
Top |
FusionGeneSequence for KIAA0232_INPP4B |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_KIAA0232_ENST00000425103_chr4_6826411_+_INPP4B_ENST00000513000_chr4_142950067_-_121aa MYPICTVVVDGLPSESSSSSYPGPVSVSEMSLLHALGPVQTWLGQELEKCGIDAMIYTRYVLSLLLHDSYDYDLQEQRRMPHRECTEEYQ >In-frame_KIAA0232_ENST00000307659_chr4_6826411_+_INPP4B_ENST00000513000_chr4_142950067_-_121aa MYPICTVVVDGLPSESSSSSYPGPVSVSEMSLLHALGPVQTWLGQELEKCGIDAMIYTRYVLSLLLHDSYDYDLQEQRRMPHRECTEEYQ |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_KIAA0232_ENST00000425103_chr4_6826411_+_INPP4B_ENST00000513000_chr4_142950067_-_364nt ATGTACCCTATCTGTACAGTTGTTGTGGATGGTTTGCCATCTGAAAGCTCCTCAAGTTCTTATCCAGGCCCTGTGTCTGTTTCTGAAATG TCTCTGCTTCATGCTTTGGGTCCAGTGCAGACCTGGCTGGGACAAGAGCTCGAGAAATGTGGCATTGATGCCATGATTTACACTCGGTAT GTCCTCAGTCTTCTGCTGCATGACAGCTATGACTACGACCTGCAGGAACAGAGAAGGATGCCGCATAGAGAATGTACTGAAGAATATCAA ATGCAGAAAGTATGCTTTCAACATGCTACAGCTGATGGCTTTCCCCAAGTACTACAGACCTCCAGAGGGGACTTATGGAAAAGCTGACAC >In-frame_KIAA0232_ENST00000307659_chr4_6826411_+_INPP4B_ENST00000513000_chr4_142950067_-_364nt ATGTACCCTATCTGTACAGTTGTTGTGGATGGTTTGCCATCTGAAAGCTCCTCAAGTTCTTATCCAGGCCCTGTGTCTGTTTCTGAAATG TCTCTGCTTCATGCTTTGGGTCCAGTGCAGACCTGGCTGGGACAAGAGCTCGAGAAATGTGGCATTGATGCCATGATTTACACTCGGTAT GTCCTCAGTCTTCTGCTGCATGACAGCTATGACTACGACCTGCAGGAACAGAGAAGGATGCCGCATAGAGAATGTACTGAAGAATATCAA ATGCAGAAAGTATGCTTTCAACATGCTACAGCTGATGGCTTTCCCCAAGTACTACAGACCTCCAGAGGGGACTTATGGAAAAGCTGACAC |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_KIAA0232_ENST00000425103_chr4_6826411_+_INPP4B_ENST00000513000_chr4_142950067_-_6365nt ACGTAAGGCGCAGGCCAGGGCCGCCCGGCGCTCGGCAGCCGCCCGCAGCCCCTCGGAGCCAGAGGAGAGGCGCCCCCGCCGGCCGCCGCG CCGCCCGGCAGCCTCGGCAGGTTCTGCCGGAGACTTCCATTTGGCCTCAATGTGAAATTAAAGTAGAAAATCACATCTACATGCATGTTG CTATCAGGATGTTGATTCATTAGTCATGCCTGAAGAGGGAAAGTCTGTTTTAGGTGGCTGACTACCAGCAAAAATAAATGCTTATCCTAC ATGTCAAGCATCTCTACTTTTTACTGGAGTGAAAATCCCCTCCAGATACCAACAGAATATCAACTGCAGAAAATGCTTCACATTTTAAGG ATGTCGGCAACCTAAATTCATGTACCCTATCTGTACAGTTGTTGTGGATGGTTTGCCATCTGAAAGCTCCTCAAGTTCTTATCCAGGCCC TGTGTCTGTTTCTGAAATGTCTCTGCTTCATGCTTTGGGTCCAGTGCAGACCTGGCTGGGACAAGAGCTCGAGAAATGTGGCATTGATGC CATGATTTACACTCGGTATGTCCTCAGTCTTCTGCTGCATGACAGCTATGACTACGACCTGCAGGAACAGAGAAGGATGCCGCATAGAGA ATGTACTGAAGAATATCAAATGCAGAAAGTATGCTTTCAACATGCTACAGCTGATGGCTTTCCCCAAGTACTACAGACCTCCAGAGGGGA CTTATGGAAAAGCTGACACCTAAGTTTACCAACATGTTAATAAACAGGAACACAAATACATTTCAGTTGGATAATCTTCACCTTGGTCTT TTTTGTTTGTTTTTATTGTCATGAATTTGTGGTGGGGGAGATGATCACAGATGTTTCCCAAAATCTAGGAACTACTTCAATTCATCATCA GCATATTGCTCTGAAAGAAATCCATTTTAAAAAATCTTACATGATTCAGTACTGTCATTTCTAGTTCTAAGCTTCTATGTGTTGAGCCTA GCTGATTGAGATTGGTTCACAAAGTGTAAATTTCATTCATGAGTATTTAAATGTTTCTGAGGAAACATGGATCATTTCAATAGGACTAGG GGTGATTCACAGAGCACCACTCTCCAACCAAATGGAAGAGAGGAGAGGGGGAAAAGGAACATATTTTTTTTGTGATACAACTTAATAGCC TATGAGAACACAGTCAACCTGAGAATCAATGTAAGGGATTTAAAAAAAATGTGTAGCCACTCAATTAGGTAGAGTTAACTCATGATCTGG AATACTGAGGCAGTTTGCAGGTATGTTCCACAATGATCTCTATCATCCAGTCAAGGTGTGACTCCTCCCTTGCAACAGGCATATGCATGG AGTGAGTAAAGTGGTCAACAGACCTTTCAAAACCATGGCATCTTTTCAGAACTCTGACTTGGGTTGTGTGATCTAGCTGTGAATGTAGCA ATATAGAACGTTTAATAGAATGATAAGCAAAACACTGCAATGATCTAAAATTACAAATAAAATAAAAATGAACAACATTTTGATACCCAA AATGAAAATTCCCATCAGCCTGAACTTTATGTTGTGAAGTTCATGAATGTCAGTGAGGTATCTCTGAGATGTTTCTTAGCAGTCATCCTG GTGTAAGCATGCAGTTATGGCATAGGTTTGTGTGTGTTAATAAGCCTTTAAAACATATGCAACCACAACAAATGATAAAGTAAAACAATT ATTTTCTGTTGCCCTGAATATCAAACTTGCCCTTGCCCTTACTCAGCAAAATAACATTTATAAGTTTTCCAAAATCCCAAAGTAGAAGTT TCCTTAAAAAAATCATCTTGTATAATACCAGTATTCAAACATGGGTAAGGTTAATCACCCCCAATCACTCAGGAGATAGTTGCAGAATTT GAATTACAATCTCTTCTTACTTTCCTAGCCTGTGGCTTGTCACTTCTCCAAATTGCCATGCTAAATATGCATGAAAATTGAGGGAGAATG CTAGTTAAAAAGAAATTAGGATTTATCACTGGAATTGAAACTAAGAGTACAAAAGTCTGAACGAATGAAACTTTTCTCCAAATTTTACAA ATTCTTGTTCCTTTCTCATTAGAAGAGCATGCTATCCAAAGCATAAATCTCCCTTGAAAATAACAGAGGCTTCTTAAGCCCTCTCTTAGC TATGATCAATGGATGATATTATGCTTCCCATAGCTAATGTGATAGCTCCTTGCCTAGGATTCCTGTTGAAATAAGGATTCTAGCCCCATG TTAAGTTTTTCAAATTACTACAAATTTTAGATAAGCATTTGGAGCTTTTTATACTAGAATTATCAATTTTTTATTTTAGCTAATTACCTG TGGGCATTATACTTGAGGCAGGTACCAAACTACTTACAGCCTTTTTAATGAAAATGTGCTGTGTACTTTGAATCCATTCATAGACAAAAT TACCTTGATGTTCTCTTAACTCATTCTTTATTTTAGTGATTAAATACAACCTTTGAGTTGTTCAATATCATTTGAAAATGGTAGGATTTG TGGTTATTTTCATTACCCTATTAGATTTAAGATAGGCTGGGATGACAGAGGCCTCCTTGAATAGCTATGAAGCCTCATTCAGCATATCAA ATGGTAGTCTGAGTTCTAAGAAACCTTAAGTAATTTATCATTCTGTAAATACTCTTATAAGCAATAATTTTTATTTGTATTTTTGAAAAC AAACTACTTAAATATGGAAAAATATTAACTGGAAAGCCAGCAGTAGGGTTTTCTATTTTTAAAAGACATTTCAAGGATTTCCTGTAATCC CAGCACTTTGGGAGCCAAGGTGGATAGATCACCTGAGGTCAGGAATTGGAGATCAGCCTGGCCAACATGGTGAAACCCCATCTCTACTAA AGATACAAAAATTAGCTGGATGTGGTGGCACACACGTGTAATCCCAGCTACTTGGGAGGCTGAGGCAAGAGAATCGCTTGAACCCCGGAG GCGGAGGTTGCAGTGAGCTGAGATCATGCCATTGCACTCCAGCCTGGGTGAAAAGAGCGAAACTCCATCTTTAAATAAGTAAATAAATGA ATAATATAGAAGTCTCAAATTATAGTGCTTACTGTAATACAAATGCTTATGAATTTTCATTCATTACCATAGTCATCTGCATTTCCTTAT AGAAAGCCTGTACTGGTGCAAACTTCTAAAAGTGGATTTCATCAAGAAAATGTGTTTCATAGAGACAACAATATTGCTTTTTTCCTGAGA GGCAGTTCATTCTTAAACAACCACTTCACTATTTCTTAAGTTATTAAGGCTAAATCAAAGAGCAAATGTTAAAGTGTTTAAATCTCTCTT GAACAAACACAGCCACAGTCATGCTATTCTATCTATATTTTCACTTAAAAGATACACCAGCAGACCTATTTTAGGAGGTCATATTGAGCC AAAAAATGAACTGAGCAAATGACATTTCCAAACTCTTTTTTTGCTCAAAAATAATATGTTCCCCTTTGATATTAAATGCAGATATCAATT CTGGATTAGCTATTTACTGAGCCCTAGGAAAAACATATTTAAAGACAAGGAAACCATTCATTTACATCTCATATCATTGCTTTTTGCTTT TAAATATCGCCTTGAGGTTTGTCTACACTCTGCCAAAACAATCCCTGAACATAAGTTTGGTCAGCCTCATAATTCAGTGAGTCGAGCAAC CATTTGTTCCAAGTGATAAATTGTACTAAATGACAAACTGCCCAATCAGGGCAGAGCTCCATGGACCCAGCCTCCAGCCCTTATTTTATA AGACTAACCCCTCTTCTGAAAAACTCTGAAGGCTTAAAAGCTAGCATTTGGATGGAGGATACTTCCTTTTTATCCTTCAGCTATGTATGG CACTTTACATAAAATAAGAGGTAAAAAAGGAGAGAAACTGATGTGTATAAAGTAATGCCTTTCTTCCCAAGCAAATCAAACCTCTCCCTA TGTAAAAGTTGATAGTGTACCAAGAGACACAATACCACTGGTGGGCTGGAACTAGCTCGTTCTGATGCATAAAAGTTGATAATTAAAGTA CCAGAAATTTTGTAAGCTAGTTGTTAAACATTACCATTATTAAATATGAAATTATAAAACACAGTGGAATACATTAAAAACCAATGTAAT AATCAAAACATACCACTTCCCAATTATTTTACTACCTTATACTATTTATTAGTACTCTTGAGTCTATTTAGGTCTATTACATCTTTACAG TGAAAACAGGATACAATATTGTGCTACTGTGGGTCTCTTCCTGACTGCAGATTCAGTAACATGGTGTTCGTAGCTTGAAACTGTCCACAG TGGGAGTATTTAACACCATAGAAACTGGCTGGCAAATGCTACAAACTAGCAATTTTAATTCCTGGAAAGGCAATTGTTGAGCATTTACCA GCACACAATGAATGCCATATTCTTTTTTTTTTATTAGGAAATAAATTATTGGAGGCAGTATAAAATTATTTAAAAAGTATCAAATGCAAT CCCTTATCTTCAGATGGCTATAATTTTGGTTATATAAATGTTTTGGTTTTTACCTTCTTTAAAGACTCCTATTAGGTTAAAAGTCATATT TGATGACTATATTTTATTCATAATTAAATTATTAAATCACCTTTTCTCCTGATAATGCTTTGCCAGAGAATTCTTAGCAATTCAACTGTA GTCTAAGCAATAACTCAGGGCTAAATTCAGGGAACTGTTAGCCCAATCAGATATCACTAAAAATGTACTTCACCATCTATTTTGGAGTTT ATAATTTTGGCATTTGCTAAAAGTAGGAAAAACAGTAACATATTACTGTGCCCAGATTCTAATAAATATAGCTCAATTGAAACCAAAACT GTTACATTAAACAAATTACACTCTGGCACTATGCTAAATCACCACAGATGTTTTAGGTGTTTGATTTCCAAGCAGGATGGTATATCATTT GTTTGGTTCAATATATGAGGCACCATTTGTAGTCTTTTAGGAAATAAATTAGCTTTTATCACAGATTTAGGAAACTTGTCTAAAAAAACT GTGATCATCAGTTACAGAGGGAAGGAAACATATTGAACACAAGGCATCATAGTAGCTGGAGGCCTTAAAAATTATGCACGACCAAAAAGA ATGATTTGGTGAGAGATGTGTAGCTGATTGACAATTTTAGTGTGAATTCATATTCATTTAACCCAGCAGCAATCTACATAAGCTATGCTT TTTCCCACCTGTATTTATGTTTCTTAGCTTATAAAGTCCCAATATATTATATCTTTTGTTGCTTTGGCAGTTTTAATTTAGAGCTCTGCG TTCACAGAGATGCCACCTATAGCAAAAACTATCTTTAAGAATTGGAAAATAAAATGAATGTTTTAGATAAAATATTGCAAGCCATTATGT GTAGAGTTAATGTATGGAAATTTGCATTTGTTTTTCTGAATCATGGTGTACATTAATCACTCATTGAATTCTATTTCTAAGCAAATAAGA GAATCAAACATTTCTAAAAGGAACATATGTCTTGCTATTAATAACAAGGAGACAGGAAAAATAGTAAGGTAATATAAGCAAAAAAAAAAA TGTAATGAATTTAGCTATCCTAAATTGGAATTTTTACAGATTGCATGCATACTTAGAATTTTAAATTTTTAAAAGATTTACAATTGAGTA TGGTACCCACAGAGAGTGAGTACCAAGGGAAGGAAGACCTAATACAAGTGATGTTGCCTGATAAATCACATCTTGCCAAAAAAAATATAT TTTAGTAAATACAGTTCTTTAGGAAGAAAAATGTTGCCCTTTCACACTCACAGTGTAAATACATTCATAATATTCCTTCAATCATCTAAA TTACCGCCAGGTCATGAAAGGACGCGATCAATGATGACCTATTGCACTCACAGGTAACATTGACTCAAATTTTGGCAATATTGCTATATT ATCTAGATAATTCTTGTGATGTTTTTATGTCACTATCAACATTAAAAATATTTTGTTAAACAACTATGAAACTTTCAAAAGTTTGCATAT AACTGTATGGGCACTCTCATTTCACTGCATACATACAATACTTTGTATACACATACTTCTCGTGTGGATATTTTATAATTTTATTTAATC TAACATTTAACTTTTAGGTTTTTGTGGTACTCATCTGAAAGGTTGGCATTTGTTTTCTTTTTATGTTATATATGTATTTTAGATGAATCA ATAATGTGTATTCCTAGAAATTTTTTCTAGGCATAAATAGATCATTTTATGTTGGCATTTAAGAGATATCATTTTTGTTTTATTGTTCTG >In-frame_KIAA0232_ENST00000307659_chr4_6826411_+_INPP4B_ENST00000513000_chr4_142950067_-_6441nt CGCAGGCCAGGGCCGCCCGGCGCTCGGCAGCCGCCCGCAGCCCCTCGGAGCCAGAGGAGAGGCGCCCCCGCCGGCCGCCGCGCCGCCCGG CAGCCTCGGCAGGTAGTGTACACTGATAAAGGTAGGGCGCGGTGGACTCTGCCCCTGTAACCGTTCCGGAGAATGCGTTGAGAATGAAGA CAACCAGTTCTGCCGGAGACTTCCATTTGGCCTCAATGTGAAATTAAAGTAGAAAATCACATCTACATGCATGTTGCTATCAGGATGTTG ATTCATTAGTCATGCCTGAAGAGGGAAAGTCTGTTTTAGGTGGCTGACTACCAGCAAAAATAAATGCTTATCCTACATGTCAAGCATCTC TACTTTTTACTGGAGTGAAAATCCCCTCCAGATACCAACAGAATATCAACTGCAGAAAATGCTTCACATTTTAAGGATGTCGGCAACCTA AATTCATGTACCCTATCTGTACAGTTGTTGTGGATGGTTTGCCATCTGAAAGCTCCTCAAGTTCTTATCCAGGCCCTGTGTCTGTTTCTG AAATGTCTCTGCTTCATGCTTTGGGTCCAGTGCAGACCTGGCTGGGACAAGAGCTCGAGAAATGTGGCATTGATGCCATGATTTACACTC GGTATGTCCTCAGTCTTCTGCTGCATGACAGCTATGACTACGACCTGCAGGAACAGAGAAGGATGCCGCATAGAGAATGTACTGAAGAAT ATCAAATGCAGAAAGTATGCTTTCAACATGCTACAGCTGATGGCTTTCCCCAAGTACTACAGACCTCCAGAGGGGACTTATGGAAAAGCT GACACCTAAGTTTACCAACATGTTAATAAACAGGAACACAAATACATTTCAGTTGGATAATCTTCACCTTGGTCTTTTTTGTTTGTTTTT ATTGTCATGAATTTGTGGTGGGGGAGATGATCACAGATGTTTCCCAAAATCTAGGAACTACTTCAATTCATCATCAGCATATTGCTCTGA AAGAAATCCATTTTAAAAAATCTTACATGATTCAGTACTGTCATTTCTAGTTCTAAGCTTCTATGTGTTGAGCCTAGCTGATTGAGATTG GTTCACAAAGTGTAAATTTCATTCATGAGTATTTAAATGTTTCTGAGGAAACATGGATCATTTCAATAGGACTAGGGGTGATTCACAGAG CACCACTCTCCAACCAAATGGAAGAGAGGAGAGGGGGAAAAGGAACATATTTTTTTTGTGATACAACTTAATAGCCTATGAGAACACAGT CAACCTGAGAATCAATGTAAGGGATTTAAAAAAAATGTGTAGCCACTCAATTAGGTAGAGTTAACTCATGATCTGGAATACTGAGGCAGT TTGCAGGTATGTTCCACAATGATCTCTATCATCCAGTCAAGGTGTGACTCCTCCCTTGCAACAGGCATATGCATGGAGTGAGTAAAGTGG TCAACAGACCTTTCAAAACCATGGCATCTTTTCAGAACTCTGACTTGGGTTGTGTGATCTAGCTGTGAATGTAGCAATATAGAACGTTTA ATAGAATGATAAGCAAAACACTGCAATGATCTAAAATTACAAATAAAATAAAAATGAACAACATTTTGATACCCAAAATGAAAATTCCCA TCAGCCTGAACTTTATGTTGTGAAGTTCATGAATGTCAGTGAGGTATCTCTGAGATGTTTCTTAGCAGTCATCCTGGTGTAAGCATGCAG TTATGGCATAGGTTTGTGTGTGTTAATAAGCCTTTAAAACATATGCAACCACAACAAATGATAAAGTAAAACAATTATTTTCTGTTGCCC TGAATATCAAACTTGCCCTTGCCCTTACTCAGCAAAATAACATTTATAAGTTTTCCAAAATCCCAAAGTAGAAGTTTCCTTAAAAAAATC ATCTTGTATAATACCAGTATTCAAACATGGGTAAGGTTAATCACCCCCAATCACTCAGGAGATAGTTGCAGAATTTGAATTACAATCTCT TCTTACTTTCCTAGCCTGTGGCTTGTCACTTCTCCAAATTGCCATGCTAAATATGCATGAAAATTGAGGGAGAATGCTAGTTAAAAAGAA ATTAGGATTTATCACTGGAATTGAAACTAAGAGTACAAAAGTCTGAACGAATGAAACTTTTCTCCAAATTTTACAAATTCTTGTTCCTTT CTCATTAGAAGAGCATGCTATCCAAAGCATAAATCTCCCTTGAAAATAACAGAGGCTTCTTAAGCCCTCTCTTAGCTATGATCAATGGAT GATATTATGCTTCCCATAGCTAATGTGATAGCTCCTTGCCTAGGATTCCTGTTGAAATAAGGATTCTAGCCCCATGTTAAGTTTTTCAAA TTACTACAAATTTTAGATAAGCATTTGGAGCTTTTTATACTAGAATTATCAATTTTTTATTTTAGCTAATTACCTGTGGGCATTATACTT GAGGCAGGTACCAAACTACTTACAGCCTTTTTAATGAAAATGTGCTGTGTACTTTGAATCCATTCATAGACAAAATTACCTTGATGTTCT CTTAACTCATTCTTTATTTTAGTGATTAAATACAACCTTTGAGTTGTTCAATATCATTTGAAAATGGTAGGATTTGTGGTTATTTTCATT ACCCTATTAGATTTAAGATAGGCTGGGATGACAGAGGCCTCCTTGAATAGCTATGAAGCCTCATTCAGCATATCAAATGGTAGTCTGAGT TCTAAGAAACCTTAAGTAATTTATCATTCTGTAAATACTCTTATAAGCAATAATTTTTATTTGTATTTTTGAAAACAAACTACTTAAATA TGGAAAAATATTAACTGGAAAGCCAGCAGTAGGGTTTTCTATTTTTAAAAGACATTTCAAGGATTTCCTGTAATCCCAGCACTTTGGGAG CCAAGGTGGATAGATCACCTGAGGTCAGGAATTGGAGATCAGCCTGGCCAACATGGTGAAACCCCATCTCTACTAAAGATACAAAAATTA GCTGGATGTGGTGGCACACACGTGTAATCCCAGCTACTTGGGAGGCTGAGGCAAGAGAATCGCTTGAACCCCGGAGGCGGAGGTTGCAGT GAGCTGAGATCATGCCATTGCACTCCAGCCTGGGTGAAAAGAGCGAAACTCCATCTTTAAATAAGTAAATAAATGAATAATATAGAAGTC TCAAATTATAGTGCTTACTGTAATACAAATGCTTATGAATTTTCATTCATTACCATAGTCATCTGCATTTCCTTATAGAAAGCCTGTACT GGTGCAAACTTCTAAAAGTGGATTTCATCAAGAAAATGTGTTTCATAGAGACAACAATATTGCTTTTTTCCTGAGAGGCAGTTCATTCTT AAACAACCACTTCACTATTTCTTAAGTTATTAAGGCTAAATCAAAGAGCAAATGTTAAAGTGTTTAAATCTCTCTTGAACAAACACAGCC ACAGTCATGCTATTCTATCTATATTTTCACTTAAAAGATACACCAGCAGACCTATTTTAGGAGGTCATATTGAGCCAAAAAATGAACTGA GCAAATGACATTTCCAAACTCTTTTTTTGCTCAAAAATAATATGTTCCCCTTTGATATTAAATGCAGATATCAATTCTGGATTAGCTATT TACTGAGCCCTAGGAAAAACATATTTAAAGACAAGGAAACCATTCATTTACATCTCATATCATTGCTTTTTGCTTTTAAATATCGCCTTG AGGTTTGTCTACACTCTGCCAAAACAATCCCTGAACATAAGTTTGGTCAGCCTCATAATTCAGTGAGTCGAGCAACCATTTGTTCCAAGT GATAAATTGTACTAAATGACAAACTGCCCAATCAGGGCAGAGCTCCATGGACCCAGCCTCCAGCCCTTATTTTATAAGACTAACCCCTCT TCTGAAAAACTCTGAAGGCTTAAAAGCTAGCATTTGGATGGAGGATACTTCCTTTTTATCCTTCAGCTATGTATGGCACTTTACATAAAA TAAGAGGTAAAAAAGGAGAGAAACTGATGTGTATAAAGTAATGCCTTTCTTCCCAAGCAAATCAAACCTCTCCCTATGTAAAAGTTGATA GTGTACCAAGAGACACAATACCACTGGTGGGCTGGAACTAGCTCGTTCTGATGCATAAAAGTTGATAATTAAAGTACCAGAAATTTTGTA AGCTAGTTGTTAAACATTACCATTATTAAATATGAAATTATAAAACACAGTGGAATACATTAAAAACCAATGTAATAATCAAAACATACC ACTTCCCAATTATTTTACTACCTTATACTATTTATTAGTACTCTTGAGTCTATTTAGGTCTATTACATCTTTACAGTGAAAACAGGATAC AATATTGTGCTACTGTGGGTCTCTTCCTGACTGCAGATTCAGTAACATGGTGTTCGTAGCTTGAAACTGTCCACAGTGGGAGTATTTAAC ACCATAGAAACTGGCTGGCAAATGCTACAAACTAGCAATTTTAATTCCTGGAAAGGCAATTGTTGAGCATTTACCAGCACACAATGAATG CCATATTCTTTTTTTTTTATTAGGAAATAAATTATTGGAGGCAGTATAAAATTATTTAAAAAGTATCAAATGCAATCCCTTATCTTCAGA TGGCTATAATTTTGGTTATATAAATGTTTTGGTTTTTACCTTCTTTAAAGACTCCTATTAGGTTAAAAGTCATATTTGATGACTATATTT TATTCATAATTAAATTATTAAATCACCTTTTCTCCTGATAATGCTTTGCCAGAGAATTCTTAGCAATTCAACTGTAGTCTAAGCAATAAC TCAGGGCTAAATTCAGGGAACTGTTAGCCCAATCAGATATCACTAAAAATGTACTTCACCATCTATTTTGGAGTTTATAATTTTGGCATT TGCTAAAAGTAGGAAAAACAGTAACATATTACTGTGCCCAGATTCTAATAAATATAGCTCAATTGAAACCAAAACTGTTACATTAAACAA ATTACACTCTGGCACTATGCTAAATCACCACAGATGTTTTAGGTGTTTGATTTCCAAGCAGGATGGTATATCATTTGTTTGGTTCAATAT ATGAGGCACCATTTGTAGTCTTTTAGGAAATAAATTAGCTTTTATCACAGATTTAGGAAACTTGTCTAAAAAAACTGTGATCATCAGTTA CAGAGGGAAGGAAACATATTGAACACAAGGCATCATAGTAGCTGGAGGCCTTAAAAATTATGCACGACCAAAAAGAATGATTTGGTGAGA GATGTGTAGCTGATTGACAATTTTAGTGTGAATTCATATTCATTTAACCCAGCAGCAATCTACATAAGCTATGCTTTTTCCCACCTGTAT TTATGTTTCTTAGCTTATAAAGTCCCAATATATTATATCTTTTGTTGCTTTGGCAGTTTTAATTTAGAGCTCTGCGTTCACAGAGATGCC ACCTATAGCAAAAACTATCTTTAAGAATTGGAAAATAAAATGAATGTTTTAGATAAAATATTGCAAGCCATTATGTGTAGAGTTAATGTA TGGAAATTTGCATTTGTTTTTCTGAATCATGGTGTACATTAATCACTCATTGAATTCTATTTCTAAGCAAATAAGAGAATCAAACATTTC TAAAAGGAACATATGTCTTGCTATTAATAACAAGGAGACAGGAAAAATAGTAAGGTAATATAAGCAAAAAAAAAAATGTAATGAATTTAG CTATCCTAAATTGGAATTTTTACAGATTGCATGCATACTTAGAATTTTAAATTTTTAAAAGATTTACAATTGAGTATGGTACCCACAGAG AGTGAGTACCAAGGGAAGGAAGACCTAATACAAGTGATGTTGCCTGATAAATCACATCTTGCCAAAAAAAATATATTTTAGTAAATACAG TTCTTTAGGAAGAAAAATGTTGCCCTTTCACACTCACAGTGTAAATACATTCATAATATTCCTTCAATCATCTAAATTACCGCCAGGTCA TGAAAGGACGCGATCAATGATGACCTATTGCACTCACAGGTAACATTGACTCAAATTTTGGCAATATTGCTATATTATCTAGATAATTCT TGTGATGTTTTTATGTCACTATCAACATTAAAAATATTTTGTTAAACAACTATGAAACTTTCAAAAGTTTGCATATAACTGTATGGGCAC TCTCATTTCACTGCATACATACAATACTTTGTATACACATACTTCTCGTGTGGATATTTTATAATTTTATTTAATCTAACATTTAACTTT TAGGTTTTTGTGGTACTCATCTGAAAGGTTGGCATTTGTTTTCTTTTTATGTTATATATGTATTTTAGATGAATCAATAATGTGTATTCC TAGAAATTTTTTCTAGGCATAAATAGATCATTTTATGTTGGCATTTAAGAGATATCATTTTTGTTTTATTGTTCTGTGTAAACCATATTC |
Top |
FusionGenePPI for KIAA0232_INPP4B |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| KIAA0232 | SLC35F6, YWHAZ, YWHAE, ALB, DYRK1B, DYRK1A, SOCS6, USP36, FOXD4L6, AP2M1, NAT8L, KIAA1683, ZBBX, SSH3, ADAMTS4, FRMD1, RPL28, SIRT6, BRINP3, TPTE2, TRIM41, DOCK5, C4orf26, NOL9, RGS3, ZNF408, FOXD4, TSPYL6, TSPYL1, HCFC2, FGFRL1 | INPP4B | ELAVL1, PYCARD, ZNF131 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
Top |
RelatedDrugs for KIAA0232_INPP4B |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
Top |
RelatedDiseases for KIAA0232_INPP4B |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
|