|
||||||
|
 | |
| |
| |
| |
| |
|
Fusion gene ID: 18491 |
FusionGeneSummary for KDM5B_RASAL2 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: KDM5B_RASAL2 | Fusion gene ID: 18491 | Hgene | Tgene | Gene symbol | KDM5B | RASAL2 | Gene ID | 10765 | 9462 |
| Gene name | lysine demethylase 5B | RAS protein activator like 2 | |
| Synonyms | CT31|JARID1B|PLU-1|PLU1|PPP1R98|PUT1|RBBP2H1A|RBP2-H1 | NGAP | |
| Cytomap | 1q32.1 | 1q25.2 | |
| Type of gene | protein-coding | protein-coding | |
| Description | lysine-specific demethylase 5Bcancer/testis antigen 31histone demethylase JARID1Bjumonji, AT rich interactive domain 1Bjumonji/ARID domain-containing protein 1Blysine (K)-specific demethylase 5Bprotein phosphatase 1, regulatory subunit 98putative D | ras GTPase-activating protein nGAPRASAL2/ACVR1 fusionRas protein activator like 1 | |
| Modification date | 20180523 | 20180522 | |
| UniProtAcc | Q9UGL1 | Q9UJF2 | |
| Ensembl transtripts involved in fusion gene | ENST00000367265, ENST00000367264, ENST00000456180, | ENST00000448150, ENST00000367649, ENST00000465723, ENST00000462775, | |
| Fusion gene scores | * DoF score | 8 X 6 X 7=336 | 9 X 8 X 6=432 |
| # samples | 9 | 13 | |
| ** MAII score | log2(9/336*10)=-1.90046432644909 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(13/432*10)=-1.73251968913501 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: KDM5B [Title/Abstract] AND RASAL2 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | Tumor suppressor gene involved fusion gene, in-frame but not retained their domain. Tumor suppressor gene involved fusion gene, retained protein feature but frameshift. DDR (DNA damage repair) gene involved fusion gene, in-frame but not retained their domain. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | KDM5B | GO:0034720 | histone H3-K4 demethylation | 20228790 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | SKCM | TCGA-EE-A3J5-06A | KDM5B | chr1 | 202777230 | - | RASAL2 | chr1 | 178389646 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000367265 | ENST00000448150 | KDM5B | chr1 | 202777230 | - | RASAL2 | chr1 | 178389646 | + |
| In-frame | ENST00000367265 | ENST00000367649 | KDM5B | chr1 | 202777230 | - | RASAL2 | chr1 | 178389646 | + |
| 5CDS-intron | ENST00000367265 | ENST00000465723 | KDM5B | chr1 | 202777230 | - | RASAL2 | chr1 | 178389646 | + |
| 5CDS-intron | ENST00000367265 | ENST00000462775 | KDM5B | chr1 | 202777230 | - | RASAL2 | chr1 | 178389646 | + |
| In-frame | ENST00000367264 | ENST00000448150 | KDM5B | chr1 | 202777230 | - | RASAL2 | chr1 | 178389646 | + |
| In-frame | ENST00000367264 | ENST00000367649 | KDM5B | chr1 | 202777230 | - | RASAL2 | chr1 | 178389646 | + |
| 5CDS-intron | ENST00000367264 | ENST00000465723 | KDM5B | chr1 | 202777230 | - | RASAL2 | chr1 | 178389646 | + |
| 5CDS-intron | ENST00000367264 | ENST00000462775 | KDM5B | chr1 | 202777230 | - | RASAL2 | chr1 | 178389646 | + |
| intron-3CDS | ENST00000456180 | ENST00000448150 | KDM5B | chr1 | 202777230 | - | RASAL2 | chr1 | 178389646 | + |
| intron-3CDS | ENST00000456180 | ENST00000367649 | KDM5B | chr1 | 202777230 | - | RASAL2 | chr1 | 178389646 | + |
| intron-intron | ENST00000456180 | ENST00000465723 | KDM5B | chr1 | 202777230 | - | RASAL2 | chr1 | 178389646 | + |
| intron-intron | ENST00000456180 | ENST00000462775 | KDM5B | chr1 | 202777230 | - | RASAL2 | chr1 | 178389646 | + |
Top |
FusionProtFeatures for KDM5B_RASAL2 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| KDM5B | RASAL2 |
| Histone demethylase that demethylates 'Lys-4' of histoneH3, thereby playing a central role in histone code(PubMed:24952722, PubMed:27214403, PubMed:28262558). Does notdemethylate histone H3 'Lys-9' or H3 'Lys-27'. Demethylatestrimethylated, dimethylated and monomethylated H3 'Lys-4'. Acts asa transcriptional corepressor for FOXG1B and PAX9. Favors theproliferation of breast cancer cells by repressing tumorsuppressor genes such as BRCA1 and HOXA5 (PubMed:24952722). Incontrast, may act as a tumor suppressor for melanoma. Repressesthe CLOCK-ARNTL/BMAL1 heterodimer-mediated transcriptionalactivation of the core clock component PER2 (By similarity).{ECO:0000250|UniProtKB:Q80Y84, ECO:0000269|PubMed:12657635,ECO:0000269|PubMed:16645588, ECO:0000269|PubMed:17320161,ECO:0000269|PubMed:17363312, ECO:0000269|PubMed:24952722,ECO:0000269|PubMed:26645689, ECO:0000269|PubMed:26741168,ECO:0000269|PubMed:27214403, ECO:0000269|PubMed:28262558}. | Inhibitory regulator of the Ras-cyclic AMP pathway. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | >RASAL2 | chr1:202777230 | chr1:178389646 | ENST00000367649 | + | 3 | 18 | 237_243 | 188 | 1281 | Compositional bias | Note=Poly-Lys |
| Tgene | >RASAL2 | chr1:202777230 | chr1:178389646 | ENST00000367649 | + | 3 | 18 | 922_925 | 188 | 1281 | Compositional bias | Note=Poly-Ser |
| Tgene | >RASAL2 | chr1:202777230 | chr1:178389646 | ENST00000462775 | + | 1 | 16 | 237_243 | 40 | 1140 | Compositional bias | Note=Poly-Lys |
| Tgene | >RASAL2 | chr1:202777230 | chr1:178389646 | ENST00000462775 | + | 1 | 16 | 922_925 | 40 | 1140 | Compositional bias | Note=Poly-Ser |
| Tgene | >RASAL2 | chr1:202777230 | chr1:178389646 | ENST00000367649 | + | 3 | 18 | 327_519 | 188 | 1281 | Domain | Ras-GAP |
| Tgene | >RASAL2 | chr1:202777230 | chr1:178389646 | ENST00000462775 | + | 1 | 16 | 170_266 | 40 | 1140 | Domain | Note=C2 |
| Tgene | >RASAL2 | chr1:202777230 | chr1:178389646 | ENST00000462775 | + | 1 | 16 | 327_519 | 40 | 1140 | Domain | Ras-GAP |
| Tgene | >RASAL2 | chr1:202777230 | chr1:178389646 | ENST00000462775 | + | 1 | 16 | 41_158 | 40 | 1140 | Domain | Note=PH |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >KDM5B | chr1:202777230 | chr1:178389646 | ENST00000367264 | - | 1 | 28 | 1434_1439 | 68 | 1581 | Compositional bias | Note=Poly-Lys |
| Hgene | >KDM5B | chr1:202777230 | chr1:178389646 | ENST00000367265 | - | 1 | 27 | 1434_1439 | 68 | 1545 | Compositional bias | Note=Poly-Lys |
| Hgene | >KDM5B | chr1:202777230 | chr1:178389646 | ENST00000367264 | - | 1 | 28 | 32_73 | 68 | 1581 | Domain | JmjN |
| Hgene | >KDM5B | chr1:202777230 | chr1:178389646 | ENST00000367264 | - | 1 | 28 | 453_619 | 68 | 1581 | Domain | JmjC |
| Hgene | >KDM5B | chr1:202777230 | chr1:178389646 | ENST00000367264 | - | 1 | 28 | 97_187 | 68 | 1581 | Domain | ARID |
| Hgene | >KDM5B | chr1:202777230 | chr1:178389646 | ENST00000367265 | - | 1 | 27 | 32_73 | 68 | 1545 | Domain | JmjN |
| Hgene | >KDM5B | chr1:202777230 | chr1:178389646 | ENST00000367265 | - | 1 | 27 | 453_619 | 68 | 1545 | Domain | JmjC |
| Hgene | >KDM5B | chr1:202777230 | chr1:178389646 | ENST00000367265 | - | 1 | 27 | 97_187 | 68 | 1545 | Domain | ARID |
| Hgene | >KDM5B | chr1:202777230 | chr1:178389646 | ENST00000367264 | - | 1 | 28 | 1176_1224 | 68 | 1581 | Zinc finger | PHD-type 2 |
| Hgene | >KDM5B | chr1:202777230 | chr1:178389646 | ENST00000367264 | - | 1 | 28 | 1484_1538 | 68 | 1581 | Zinc finger | PHD-type 3 |
| Hgene | >KDM5B | chr1:202777230 | chr1:178389646 | ENST00000367264 | - | 1 | 28 | 309_359 | 68 | 1581 | Zinc finger | PHD-type 1 |
| Hgene | >KDM5B | chr1:202777230 | chr1:178389646 | ENST00000367264 | - | 1 | 28 | 692_744 | 68 | 1581 | Zinc finger | C5HC2 |
| Hgene | >KDM5B | chr1:202777230 | chr1:178389646 | ENST00000367265 | - | 1 | 27 | 1176_1224 | 68 | 1545 | Zinc finger | PHD-type 2 |
| Hgene | >KDM5B | chr1:202777230 | chr1:178389646 | ENST00000367265 | - | 1 | 27 | 1484_1538 | 68 | 1545 | Zinc finger | PHD-type 3 |
| Hgene | >KDM5B | chr1:202777230 | chr1:178389646 | ENST00000367265 | - | 1 | 27 | 309_359 | 68 | 1545 | Zinc finger | PHD-type 1 |
| Hgene | >KDM5B | chr1:202777230 | chr1:178389646 | ENST00000367265 | - | 1 | 27 | 692_744 | 68 | 1545 | Zinc finger | C5HC2 |
| Tgene | RASAL2 | chr1:202777230 | chr1:178389646 | ENST00000367649 | + | 3 | 18 | 170_266 | 188 | 1281 | Domain | Note=C2 |
| Tgene | RASAL2 | chr1:202777230 | chr1:178389646 | ENST00000367649 | + | 3 | 18 | 41_158 | 188 | 1281 | Domain | Note=PH |
Top |
FusionGeneSequence for KDM5B_RASAL2 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_KDM5B_ENST00000367265_chr1_202777230_-_RASAL2_ENST00000448150_chr1_178389646_+_1168aa MEAATTLHPGPRPALPLGGPGPLGEFLPPPECPVFEPSWEEFADPFAFIHKIRPIAEQTGICKVRPPPGFFSKRLKGSIKRTKSQSKLDR NTSFRLPSLRSTDDRSRGLPKLKESRSHESLLSPCSTVECLDLGRGEPVSVKPLHSSILGQDFCFEVTYLSGSKCFSCNSASERDKWMEN LRRTVQPNKDNCRRAENVLRLWIIEAKDLAPKKKYFCELCLDDTLFARTTSKTKADNIFWGEHFEFFSLPPLHSITVHIYKDVEKKKKKD KNNYVGLVNIPTASVTGRQFVEKWYPVSTPTPNKGKTGGPSIRIKSRFQTITILPMEQYKEFAEFVTSNYTMLCSVLEPVISVRNKEELA CALVHILQSTGRAKDFLTDLVMSEVDRCGEHDVLIFRENTIATKSIEEYLKLVGQQYLHDALGEFIKALYESDENCEVDPSKCSSSELID HQSNLKMCCELAFCKIINSYCVFPRELKEVFASWKQQCLNRGKQDISERLISASLFLRFLCPAIMSPSLFNLMQEYPDDRTSRTLTLIAK VIQNLANFAKFGNKEEYMAFMNDFLEHEWGGMKRFLLEISNPDTISNTPGFDGYIDLGRELSVLHSLLWEVVSQLDKGENSFLQATVAKL GPLPRVLADITKSLTNPTPIQQQLRRFTEHNSSPNVSGSLSSGLQKIFEDPTDSDLHKLKSPSQDNTDSYFRGKTLLLVQQASSQSMTYS EKDERESSLPNGRSVSLMDLQDTHAAQVEHASVMLDVPIRLTGSQLSITQVASIKQLRETQSTPQSAPQVRRPLHPALNQPGGLQPLSFQ NPVYHLNNPIPAMPKASIDSSLENLSTASSRSQSNSEDFKLSGPSNSSMEDFTKRSTQSEDFSRRHTVPDRHIPLALPRQNSTGQAQIRK VDQGGLGARAKAPPSLPHSASLRSTGSMSVVSAALVAEPVQNGSRSRQQSSSSRESPVPKVRAIQRQQTQQVQSPVDSATMSPVERTAAW VLNNGQYEEDVEETEQNLDEAKHAEKYEQEITKLKERLRVSSRRLEEYERRLLVQEQQMQKLLLEYKARLEDSEERLRRQQEEKDSQMKS >In-frame_KDM5B_ENST00000367265_chr1_202777230_-_RASAL2_ENST00000367649_chr1_178389646_+_1161aa MEAATTLHPGPRPALPLGGPGPLGEFLPPPECPVFEPSWEEFADPFAFIHKIRPIAEQTGICKVRPPPGFFSKRLKGSIKRTKSQSKLDR NTSFRLPSLRSTDDRSRGLPKLKESRSHESLLSPCSTVECLDLGRGEPVSVKPLHSSILGQDFCFEVTYLSGSKCFSCNSASERDKWMEN LRRTVQPNKDNCRRAENVLRLWIIEAKDLAPKKKYFCELCLDDTLFARTTSKTKADNIFWGEHFEFFSLPPLHSITVHIYKDVEKKKKKD KNNYVGLVNIPTASVTGRQFVEKWYPVSTPTPNKGKTGGPSIRIKSRFQTITILPMEQYKEFAEFVTSNYTMLCSVLEPVISVRNKEELA CALVHILQSTGRAKDFLTDLVMSEVDRCGEHDVLIFRENTIATKSIEEYLKLVGQQYLHDALGEFIKALYESDENCEVDPSKCSSSELID HQSNLKMCCELAFCKIINSYCVFPRELKEVFASWKQQCLNRGKQDISERLISASLFLRFLCPAIMSPSLFNLMQEYPDDRTSRTLTLIAK VIQNLANFAKFGNKEEYMAFMNDFLEHEWGGMKRFLLEISNPDTISNTPGFDGYIDLGRELSVLHSLLWEVVSQLDKATVAKLGPLPRVL ADITKSLTNPTPIQQQLRRFTEHNSSPNVSGSLSSGLQKIFEDPTDSDLHKLKSPSQDNTDSYFRGKTLLLVQQASSQSMTYSEKDERES SLPNGRSVSLMDLQDTHAAQVEHASVMLDVPIRLTGSQLSITQVASIKQLRETQSTPQSAPQVRRPLHPALNQPGGLQPLSFQNPVYHLN NPIPAMPKASIDSSLENLSTASSRSQSNSEDFKLSGPSNSSMEDFTKRSTQSEDFSRRHTVPDRHIPLALPRQNSTGQAQIRKVDQGGLG ARAKAPPSLPHSASLRSTGSMSVVSAALVAEPVQNGSRSRQQSSSSRESPVPKVRAIQRQQTQQVQSPVDSATMSPVERTAAWVLNNGQY EEDVEETEQNLDEAKHAEKYEQEITKLKERLRVSSRRLEEYERRLLVQEQQMQKLLLEYKARLEDSEERLRRQQEEKDSQMKSIISRLMA >In-frame_KDM5B_ENST00000367264_chr1_202777230_-_RASAL2_ENST00000448150_chr1_178389646_+_1168aa MEAATTLHPGPRPALPLGGPGPLGEFLPPPECPVFEPSWEEFADPFAFIHKIRPIAEQTGICKVRPPPGFFSKRLKGSIKRTKSQSKLDR NTSFRLPSLRSTDDRSRGLPKLKESRSHESLLSPCSTVECLDLGRGEPVSVKPLHSSILGQDFCFEVTYLSGSKCFSCNSASERDKWMEN LRRTVQPNKDNCRRAENVLRLWIIEAKDLAPKKKYFCELCLDDTLFARTTSKTKADNIFWGEHFEFFSLPPLHSITVHIYKDVEKKKKKD KNNYVGLVNIPTASVTGRQFVEKWYPVSTPTPNKGKTGGPSIRIKSRFQTITILPMEQYKEFAEFVTSNYTMLCSVLEPVISVRNKEELA CALVHILQSTGRAKDFLTDLVMSEVDRCGEHDVLIFRENTIATKSIEEYLKLVGQQYLHDALGEFIKALYESDENCEVDPSKCSSSELID HQSNLKMCCELAFCKIINSYCVFPRELKEVFASWKQQCLNRGKQDISERLISASLFLRFLCPAIMSPSLFNLMQEYPDDRTSRTLTLIAK VIQNLANFAKFGNKEEYMAFMNDFLEHEWGGMKRFLLEISNPDTISNTPGFDGYIDLGRELSVLHSLLWEVVSQLDKGENSFLQATVAKL GPLPRVLADITKSLTNPTPIQQQLRRFTEHNSSPNVSGSLSSGLQKIFEDPTDSDLHKLKSPSQDNTDSYFRGKTLLLVQQASSQSMTYS EKDERESSLPNGRSVSLMDLQDTHAAQVEHASVMLDVPIRLTGSQLSITQVASIKQLRETQSTPQSAPQVRRPLHPALNQPGGLQPLSFQ NPVYHLNNPIPAMPKASIDSSLENLSTASSRSQSNSEDFKLSGPSNSSMEDFTKRSTQSEDFSRRHTVPDRHIPLALPRQNSTGQAQIRK VDQGGLGARAKAPPSLPHSASLRSTGSMSVVSAALVAEPVQNGSRSRQQSSSSRESPVPKVRAIQRQQTQQVQSPVDSATMSPVERTAAW VLNNGQYEEDVEETEQNLDEAKHAEKYEQEITKLKERLRVSSRRLEEYERRLLVQEQQMQKLLLEYKARLEDSEERLRRQQEEKDSQMKS >In-frame_KDM5B_ENST00000367264_chr1_202777230_-_RASAL2_ENST00000367649_chr1_178389646_+_1161aa MEAATTLHPGPRPALPLGGPGPLGEFLPPPECPVFEPSWEEFADPFAFIHKIRPIAEQTGICKVRPPPGFFSKRLKGSIKRTKSQSKLDR NTSFRLPSLRSTDDRSRGLPKLKESRSHESLLSPCSTVECLDLGRGEPVSVKPLHSSILGQDFCFEVTYLSGSKCFSCNSASERDKWMEN LRRTVQPNKDNCRRAENVLRLWIIEAKDLAPKKKYFCELCLDDTLFARTTSKTKADNIFWGEHFEFFSLPPLHSITVHIYKDVEKKKKKD KNNYVGLVNIPTASVTGRQFVEKWYPVSTPTPNKGKTGGPSIRIKSRFQTITILPMEQYKEFAEFVTSNYTMLCSVLEPVISVRNKEELA CALVHILQSTGRAKDFLTDLVMSEVDRCGEHDVLIFRENTIATKSIEEYLKLVGQQYLHDALGEFIKALYESDENCEVDPSKCSSSELID HQSNLKMCCELAFCKIINSYCVFPRELKEVFASWKQQCLNRGKQDISERLISASLFLRFLCPAIMSPSLFNLMQEYPDDRTSRTLTLIAK VIQNLANFAKFGNKEEYMAFMNDFLEHEWGGMKRFLLEISNPDTISNTPGFDGYIDLGRELSVLHSLLWEVVSQLDKATVAKLGPLPRVL ADITKSLTNPTPIQQQLRRFTEHNSSPNVSGSLSSGLQKIFEDPTDSDLHKLKSPSQDNTDSYFRGKTLLLVQQASSQSMTYSEKDERES SLPNGRSVSLMDLQDTHAAQVEHASVMLDVPIRLTGSQLSITQVASIKQLRETQSTPQSAPQVRRPLHPALNQPGGLQPLSFQNPVYHLN NPIPAMPKASIDSSLENLSTASSRSQSNSEDFKLSGPSNSSMEDFTKRSTQSEDFSRRHTVPDRHIPLALPRQNSTGQAQIRKVDQGGLG ARAKAPPSLPHSASLRSTGSMSVVSAALVAEPVQNGSRSRQQSSSSRESPVPKVRAIQRQQTQQVQSPVDSATMSPVERTAAWVLNNGQY EEDVEETEQNLDEAKHAEKYEQEITKLKERLRVSSRRLEEYERRLLVQEQQMQKLLLEYKARLEDSEERLRRQQEEKDSQMKSIISRLMA |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_KDM5B_ENST00000367265_chr1_202777230_-_RASAL2_ENST00000448150_chr1_178389646_+_3504nt ATGGAGGCGGCCACCACACTGCACCCAGGCCCGCGCCCGGCGCTGCCCCTCGGGGGCCCGGGCCCGCTGGGCGAGTTCCTGCCTCCACCC GAGTGCCCGGTCTTCGAACCCAGCTGGGAAGAGTTCGCGGACCCCTTCGCTTTCATCCACAAGATCCGGCCCATAGCCGAGCAGACTGGC ATCTGTAAGGTGCGGCCGCCGCCGGGATTCTTCAGCAAGCGCCTGAAAGGCTCCATCAAGAGGACCAAAAGCCAGTCAAAGCTTGACAGA AACACGAGCTTTCGGCTTCCATCCCTTCGCAGTACAGATGACAGGTCTCGTGGGCTGCCTAAACTAAAAGAGTCACGTTCCCATGAATCC TTGCTGAGCCCATGCAGCACAGTGGAATGTCTGGATCTTGGTAGAGGGGAACCTGTATCAGTGAAACCACTTCATAGTAGCATCCTTGGA CAAGACTTCTGCTTTGAGGTTACCTACTTAAGTGGAAGTAAATGCTTCAGCTGTAATTCTGCTTCTGAGAGAGACAAGTGGATGGAAAAC CTTCGCAGGACAGTTCAACCTAATAAGGACAATTGCAGGCGAGCTGAAAATGTTCTTCGTTTATGGATCATTGAAGCCAAGGACCTTGCC CCTAAAAAGAAATATTTCTGCGAACTGTGCCTTGATGATACCCTCTTTGCTCGTACAACCAGCAAGACCAAAGCAGACAATATTTTCTGG GGCGAACATTTTGAATTCTTCAGCCTTCCACCTCTTCATAGTATCACAGTTCACATTTACAAGGATGTGGAAAAAAAGAAAAAAAAGGAC AAGAATAATTATGTAGGGCTAGTCAACATCCCCACTGCCAGTGTGACTGGTCGCCAATTTGTAGAAAAGTGGTATCCAGTGAGTACACCT ACACCCAACAAAGGAAAGACAGGAGGACCTTCTATTCGGATTAAATCACGTTTCCAAACTATCACCATTCTGCCTATGGAGCAATACAAA GAATTTGCAGAATTTGTCACCAGCAACTACACCATGCTGTGTTCTGTCCTTGAGCCAGTAATTAGTGTGAGAAATAAAGAGGAGTTGGCT TGTGCCTTAGTGCACATTCTTCAAAGTACTGGCAGAGCCAAGGATTTTCTGACTGACTTGGTGATGTCTGAGGTGGATCGTTGTGGAGAG CATGATGTCTTGATCTTCAGAGAGAACACTATTGCCACCAAATCCATTGAGGAATACCTCAAGTTGGTGGGACAACAGTATCTTCATGAC GCACTGGGGGAGTTTATCAAAGCTTTGTATGAGTCCGATGAGAACTGTGAAGTGGATCCCAGCAAATGTTCATCTAGTGAACTGATAGAC CATCAGAGCAACCTGAAAATGTGCTGTGAGCTGGCTTTCTGCAAGATCATCAACTCTTACTGTGTTTTCCCTCGTGAGTTGAAAGAAGTG TTTGCATCATGGAAGCAGCAGTGCCTGAACCGTGGCAAGCAAGACATCAGCGAGAGGCTCATCAGTGCCTCATTATTTCTCCGTTTTCTG TGTCCAGCCATTATGTCTCCCAGTCTTTTCAACCTTATGCAGGAGTATCCTGATGACCGCACATCTCGGACTCTAACTCTTATTGCCAAG GTCATTCAGAACCTGGCCAACTTTGCCAAGTTTGGTAACAAAGAGGAATACATGGCATTCATGAATGATTTTTTAGAACATGAATGGGGT GGAATGAAGCGCTTTCTTTTGGAGATCTCTAATCCAGACACCATCTCAAACACCCCAGGCTTTGATGGTTACATTGATCTGGGCCGAGAG CTTTCAGTTTTGCATTCCTTACTGTGGGAAGTAGTTTCCCAACTTGATAAGGGTGAAAATTCCTTCCTACAGGCGACCGTGGCAAAATTG GGGCCTCTCCCTCGTGTTCTTGCTGATATTACCAAGTCATTGACTAATCCTACGCCAATACAACAGCAACTGAGACGCTTCACTGAACAT AACTCCAGTCCAAATGTCAGTGGAAGCCTCTCCTCTGGGCTGCAGAAAATATTTGAAGACCCCACTGACAGTGATTTGCATAAACTAAAA TCTCCAAGCCAGGACAACACAGACAGCTACTTCAGAGGGAAAACATTATTGCTGGTTCAGCAAGCCTCCTCTCAGAGCATGACTTATTCT GAAAAGGATGAAAGGGAAAGTAGCCTTCCTAATGGTCGGAGCGTCTCCCTCATGGACCTCCAGGACACTCATGCTGCTCAAGTGGAGCAT GCATCTGTCATGCTTGATGTGCCTATACGCTTGACCGGAAGCCAGCTTTCCATAACCCAGGTGGCCAGCATCAAACAGCTGCGGGAAACC CAGAGCACTCCCCAAAGTGCACCCCAAGTGAGAAGGCCCCTGCACCCAGCCTTGAACCAGCCAGGTGGCCTTCAGCCCTTGTCGTTCCAG AACCCTGTCTATCACCTCAATAACCCAATTCCAGCAATGCCAAAGGCCTCTATAGATTCCAGTTTGGAGAACCTAAGCACTGCCAGTTCC AGAAGCCAAAGTAACAGTGAAGACTTCAAGCTCAGTGGACCCAGCAATAGCAGCATGGAAGATTTCACTAAACGTAGCACTCAGAGTGAG GACTTCTCCAGGCGGCACACGGTGCCAGATAGACACATACCTCTTGCTTTGCCACGACAAAATAGTACTGGGCAGGCCCAGATCCGAAAA GTGGACCAGGGTGGGTTAGGTGCCCGAGCCAAAGCCCCACCATCCCTGCCACACAGTGCTTCTTTACGTAGCACCGGGAGCATGTCAGTG GTGTCCGCAGCCCTGGTGGCCGAACCTGTGCAGAATGGGAGCCGGTCCCGGCAGCAGTCCTCTTCCTCCAGAGAGAGCCCTGTTCCCAAA GTTAGAGCAATCCAGAGACAACAGACACAGCAGGTTCAGTCACCTGTGGACTCTGCCACAATGTCCCCAGTAGAGAGGACAGCAGCCTGG GTTCTGAACAATGGGCAGTATGAAGAGGATGTGGAAGAAACTGAGCAAAATCTAGATGAAGCCAAGCATGCTGAGAAGTATGAACAAGAA ATTACTAAACTGAAGGAGCGCCTGAGAGTTTCCAGCCGGCGACTGGAGGAATATGAACGCCGCTTGCTGGTGCAGGAGCAGCAGATGCAG AAGCTGCTGCTGGAATACAAGGCCCGACTGGAGGACAGCGAGGAGCGGCTCCGAAGACAGCAGGAAGAAAAAGATAGCCAGATGAAAAGC ATCATCAGCAGGCTAATGGCTGTGGAAGAGGAACTGAAGAAGGATCATGCTGAGATGCAAGCAGTTATTGATGCAAAGCAGAAAATAATT GATGCACAGGAAAAACGGATCGTGTCCCTGGATTCAGCCAACACCAGACTGATGAGCGCGCTGACCCAAGTGAAGGAGCGGTACAGCATG >In-frame_KDM5B_ENST00000367265_chr1_202777230_-_RASAL2_ENST00000367649_chr1_178389646_+_3483nt ATGGAGGCGGCCACCACACTGCACCCAGGCCCGCGCCCGGCGCTGCCCCTCGGGGGCCCGGGCCCGCTGGGCGAGTTCCTGCCTCCACCC GAGTGCCCGGTCTTCGAACCCAGCTGGGAAGAGTTCGCGGACCCCTTCGCTTTCATCCACAAGATCCGGCCCATAGCCGAGCAGACTGGC ATCTGTAAGGTGCGGCCGCCGCCGGGATTCTTCAGCAAGCGCCTGAAAGGCTCCATCAAGAGGACCAAAAGCCAGTCAAAGCTTGACAGA AACACGAGCTTTCGGCTTCCATCCCTTCGCAGTACAGATGACAGGTCTCGTGGGCTGCCTAAACTAAAAGAGTCACGTTCCCATGAATCC TTGCTGAGCCCATGCAGCACAGTGGAATGTCTGGATCTTGGTAGAGGGGAACCTGTATCAGTGAAACCACTTCATAGTAGCATCCTTGGA CAAGACTTCTGCTTTGAGGTTACCTACTTAAGTGGAAGTAAATGCTTCAGCTGTAATTCTGCTTCTGAGAGAGACAAGTGGATGGAAAAC CTTCGCAGGACAGTTCAACCTAATAAGGACAATTGCAGGCGAGCTGAAAATGTTCTTCGTTTATGGATCATTGAAGCCAAGGACCTTGCC CCTAAAAAGAAATATTTCTGCGAACTGTGCCTTGATGATACCCTCTTTGCTCGTACAACCAGCAAGACCAAAGCAGACAATATTTTCTGG GGCGAACATTTTGAATTCTTCAGCCTTCCACCTCTTCATAGTATCACAGTTCACATTTACAAGGATGTGGAAAAAAAGAAAAAAAAGGAC AAGAATAATTATGTAGGGCTAGTCAACATCCCCACTGCCAGTGTGACTGGTCGCCAATTTGTAGAAAAGTGGTATCCAGTGAGTACACCT ACACCCAACAAAGGAAAGACAGGAGGACCTTCTATTCGGATTAAATCACGTTTCCAAACTATCACCATTCTGCCTATGGAGCAATACAAA GAATTTGCAGAATTTGTCACCAGCAACTACACCATGCTGTGTTCTGTCCTTGAGCCAGTAATTAGTGTGAGAAATAAAGAGGAGTTGGCT TGTGCCTTAGTGCACATTCTTCAAAGTACTGGCAGAGCCAAGGATTTTCTGACTGACTTGGTGATGTCTGAGGTGGATCGTTGTGGAGAG CATGATGTCTTGATCTTCAGAGAGAACACTATTGCCACCAAATCCATTGAGGAATACCTCAAGTTGGTGGGACAACAGTATCTTCATGAC GCACTGGGGGAGTTTATCAAAGCTTTGTATGAGTCCGATGAGAACTGTGAAGTGGATCCCAGCAAATGTTCATCTAGTGAACTGATAGAC CATCAGAGCAACCTGAAAATGTGCTGTGAGCTGGCTTTCTGCAAGATCATCAACTCTTACTGTGTTTTCCCTCGTGAGTTGAAAGAAGTG TTTGCATCATGGAAGCAGCAGTGCCTGAACCGTGGCAAGCAAGACATCAGCGAGAGGCTCATCAGTGCCTCATTATTTCTCCGTTTTCTG TGTCCAGCCATTATGTCTCCCAGTCTTTTCAACCTTATGCAGGAGTATCCTGATGACCGCACATCTCGGACTCTAACTCTTATTGCCAAG GTCATTCAGAACCTGGCCAACTTTGCCAAGTTTGGTAACAAAGAGGAATACATGGCATTCATGAATGATTTTTTAGAACATGAATGGGGT GGAATGAAGCGCTTTCTTTTGGAGATCTCTAATCCAGACACCATCTCAAACACCCCAGGCTTTGATGGTTACATTGATCTGGGCCGAGAG CTTTCAGTTTTGCATTCCTTACTGTGGGAAGTAGTTTCCCAACTTGATAAGGCGACCGTGGCAAAATTGGGGCCTCTCCCTCGTGTTCTT GCTGATATTACCAAGTCATTGACTAATCCTACGCCAATACAACAGCAACTGAGACGCTTCACTGAACATAACTCCAGTCCAAATGTCAGT GGAAGCCTCTCCTCTGGGCTGCAGAAAATATTTGAAGACCCCACTGACAGTGATTTGCATAAACTAAAATCTCCAAGCCAGGACAACACA GACAGCTACTTCAGAGGGAAAACATTATTGCTGGTTCAGCAAGCCTCCTCTCAGAGCATGACTTATTCTGAAAAGGATGAAAGGGAAAGT AGCCTTCCTAATGGTCGGAGCGTCTCCCTCATGGACCTCCAGGACACTCATGCTGCTCAAGTGGAGCATGCATCTGTCATGCTTGATGTG CCTATACGCTTGACCGGAAGCCAGCTTTCCATAACCCAGGTGGCCAGCATCAAACAGCTGCGGGAAACCCAGAGCACTCCCCAAAGTGCA CCCCAAGTGAGAAGGCCCCTGCACCCAGCCTTGAACCAGCCAGGTGGCCTTCAGCCCTTGTCGTTCCAGAACCCTGTCTATCACCTCAAT AACCCAATTCCAGCAATGCCAAAGGCCTCTATAGATTCCAGTTTGGAGAACCTAAGCACTGCCAGTTCCAGAAGCCAAAGTAACAGTGAA GACTTCAAGCTCAGTGGACCCAGCAATAGCAGCATGGAAGATTTCACTAAACGTAGCACTCAGAGTGAGGACTTCTCCAGGCGGCACACG GTGCCAGATAGACACATACCTCTTGCTTTGCCACGACAAAATAGTACTGGGCAGGCCCAGATCCGAAAAGTGGACCAGGGTGGGTTAGGT GCCCGAGCCAAAGCCCCACCATCCCTGCCACACAGTGCTTCTTTACGTAGCACCGGGAGCATGTCAGTGGTGTCCGCAGCCCTGGTGGCC GAACCTGTGCAGAATGGGAGCCGGTCCCGGCAGCAGTCCTCTTCCTCCAGAGAGAGCCCTGTTCCCAAAGTTAGAGCAATCCAGAGACAA CAGACACAGCAGGTTCAGTCACCTGTGGACTCTGCCACAATGTCCCCAGTAGAGAGGACAGCAGCCTGGGTTCTGAACAATGGGCAGTAT GAAGAGGATGTGGAAGAAACTGAGCAAAATCTAGATGAAGCCAAGCATGCTGAGAAGTATGAACAAGAAATTACTAAACTGAAGGAGCGC CTGAGAGTTTCCAGCCGGCGACTGGAGGAATATGAACGCCGCTTGCTGGTGCAGGAGCAGCAGATGCAGAAGCTGCTGCTGGAATACAAG GCCCGACTGGAGGACAGCGAGGAGCGGCTCCGAAGACAGCAGGAAGAAAAAGATAGCCAGATGAAAAGCATCATCAGCAGGCTAATGGCT GTGGAAGAGGAACTGAAGAAGGATCATGCTGAGATGCAAGCAGTTATTGATGCAAAGCAGAAAATAATTGATGCACAGGAAAAACGGATC GTGTCCCTGGATTCAGCCAACACCAGACTGATGAGCGCGCTGACCCAAGTGAAGGAGCGGTACAGCATGCAGGTCCGCAATGGCATCTCC >In-frame_KDM5B_ENST00000367264_chr1_202777230_-_RASAL2_ENST00000448150_chr1_178389646_+_3504nt ATGGAGGCGGCCACCACACTGCACCCAGGCCCGCGCCCGGCGCTGCCCCTCGGGGGCCCGGGCCCGCTGGGCGAGTTCCTGCCTCCACCC GAGTGCCCGGTCTTCGAACCCAGCTGGGAAGAGTTCGCGGACCCCTTCGCTTTCATCCACAAGATCCGGCCCATAGCCGAGCAGACTGGC ATCTGTAAGGTGCGGCCGCCGCCGGGATTCTTCAGCAAGCGCCTGAAAGGCTCCATCAAGAGGACCAAAAGCCAGTCAAAGCTTGACAGA AACACGAGCTTTCGGCTTCCATCCCTTCGCAGTACAGATGACAGGTCTCGTGGGCTGCCTAAACTAAAAGAGTCACGTTCCCATGAATCC TTGCTGAGCCCATGCAGCACAGTGGAATGTCTGGATCTTGGTAGAGGGGAACCTGTATCAGTGAAACCACTTCATAGTAGCATCCTTGGA CAAGACTTCTGCTTTGAGGTTACCTACTTAAGTGGAAGTAAATGCTTCAGCTGTAATTCTGCTTCTGAGAGAGACAAGTGGATGGAAAAC CTTCGCAGGACAGTTCAACCTAATAAGGACAATTGCAGGCGAGCTGAAAATGTTCTTCGTTTATGGATCATTGAAGCCAAGGACCTTGCC CCTAAAAAGAAATATTTCTGCGAACTGTGCCTTGATGATACCCTCTTTGCTCGTACAACCAGCAAGACCAAAGCAGACAATATTTTCTGG GGCGAACATTTTGAATTCTTCAGCCTTCCACCTCTTCATAGTATCACAGTTCACATTTACAAGGATGTGGAAAAAAAGAAAAAAAAGGAC AAGAATAATTATGTAGGGCTAGTCAACATCCCCACTGCCAGTGTGACTGGTCGCCAATTTGTAGAAAAGTGGTATCCAGTGAGTACACCT ACACCCAACAAAGGAAAGACAGGAGGACCTTCTATTCGGATTAAATCACGTTTCCAAACTATCACCATTCTGCCTATGGAGCAATACAAA GAATTTGCAGAATTTGTCACCAGCAACTACACCATGCTGTGTTCTGTCCTTGAGCCAGTAATTAGTGTGAGAAATAAAGAGGAGTTGGCT TGTGCCTTAGTGCACATTCTTCAAAGTACTGGCAGAGCCAAGGATTTTCTGACTGACTTGGTGATGTCTGAGGTGGATCGTTGTGGAGAG CATGATGTCTTGATCTTCAGAGAGAACACTATTGCCACCAAATCCATTGAGGAATACCTCAAGTTGGTGGGACAACAGTATCTTCATGAC GCACTGGGGGAGTTTATCAAAGCTTTGTATGAGTCCGATGAGAACTGTGAAGTGGATCCCAGCAAATGTTCATCTAGTGAACTGATAGAC CATCAGAGCAACCTGAAAATGTGCTGTGAGCTGGCTTTCTGCAAGATCATCAACTCTTACTGTGTTTTCCCTCGTGAGTTGAAAGAAGTG TTTGCATCATGGAAGCAGCAGTGCCTGAACCGTGGCAAGCAAGACATCAGCGAGAGGCTCATCAGTGCCTCATTATTTCTCCGTTTTCTG TGTCCAGCCATTATGTCTCCCAGTCTTTTCAACCTTATGCAGGAGTATCCTGATGACCGCACATCTCGGACTCTAACTCTTATTGCCAAG GTCATTCAGAACCTGGCCAACTTTGCCAAGTTTGGTAACAAAGAGGAATACATGGCATTCATGAATGATTTTTTAGAACATGAATGGGGT GGAATGAAGCGCTTTCTTTTGGAGATCTCTAATCCAGACACCATCTCAAACACCCCAGGCTTTGATGGTTACATTGATCTGGGCCGAGAG CTTTCAGTTTTGCATTCCTTACTGTGGGAAGTAGTTTCCCAACTTGATAAGGGTGAAAATTCCTTCCTACAGGCGACCGTGGCAAAATTG GGGCCTCTCCCTCGTGTTCTTGCTGATATTACCAAGTCATTGACTAATCCTACGCCAATACAACAGCAACTGAGACGCTTCACTGAACAT AACTCCAGTCCAAATGTCAGTGGAAGCCTCTCCTCTGGGCTGCAGAAAATATTTGAAGACCCCACTGACAGTGATTTGCATAAACTAAAA TCTCCAAGCCAGGACAACACAGACAGCTACTTCAGAGGGAAAACATTATTGCTGGTTCAGCAAGCCTCCTCTCAGAGCATGACTTATTCT GAAAAGGATGAAAGGGAAAGTAGCCTTCCTAATGGTCGGAGCGTCTCCCTCATGGACCTCCAGGACACTCATGCTGCTCAAGTGGAGCAT GCATCTGTCATGCTTGATGTGCCTATACGCTTGACCGGAAGCCAGCTTTCCATAACCCAGGTGGCCAGCATCAAACAGCTGCGGGAAACC CAGAGCACTCCCCAAAGTGCACCCCAAGTGAGAAGGCCCCTGCACCCAGCCTTGAACCAGCCAGGTGGCCTTCAGCCCTTGTCGTTCCAG AACCCTGTCTATCACCTCAATAACCCAATTCCAGCAATGCCAAAGGCCTCTATAGATTCCAGTTTGGAGAACCTAAGCACTGCCAGTTCC AGAAGCCAAAGTAACAGTGAAGACTTCAAGCTCAGTGGACCCAGCAATAGCAGCATGGAAGATTTCACTAAACGTAGCACTCAGAGTGAG GACTTCTCCAGGCGGCACACGGTGCCAGATAGACACATACCTCTTGCTTTGCCACGACAAAATAGTACTGGGCAGGCCCAGATCCGAAAA GTGGACCAGGGTGGGTTAGGTGCCCGAGCCAAAGCCCCACCATCCCTGCCACACAGTGCTTCTTTACGTAGCACCGGGAGCATGTCAGTG GTGTCCGCAGCCCTGGTGGCCGAACCTGTGCAGAATGGGAGCCGGTCCCGGCAGCAGTCCTCTTCCTCCAGAGAGAGCCCTGTTCCCAAA GTTAGAGCAATCCAGAGACAACAGACACAGCAGGTTCAGTCACCTGTGGACTCTGCCACAATGTCCCCAGTAGAGAGGACAGCAGCCTGG GTTCTGAACAATGGGCAGTATGAAGAGGATGTGGAAGAAACTGAGCAAAATCTAGATGAAGCCAAGCATGCTGAGAAGTATGAACAAGAA ATTACTAAACTGAAGGAGCGCCTGAGAGTTTCCAGCCGGCGACTGGAGGAATATGAACGCCGCTTGCTGGTGCAGGAGCAGCAGATGCAG AAGCTGCTGCTGGAATACAAGGCCCGACTGGAGGACAGCGAGGAGCGGCTCCGAAGACAGCAGGAAGAAAAAGATAGCCAGATGAAAAGC ATCATCAGCAGGCTAATGGCTGTGGAAGAGGAACTGAAGAAGGATCATGCTGAGATGCAAGCAGTTATTGATGCAAAGCAGAAAATAATT GATGCACAGGAAAAACGGATCGTGTCCCTGGATTCAGCCAACACCAGACTGATGAGCGCGCTGACCCAAGTGAAGGAGCGGTACAGCATG >In-frame_KDM5B_ENST00000367264_chr1_202777230_-_RASAL2_ENST00000367649_chr1_178389646_+_3483nt ATGGAGGCGGCCACCACACTGCACCCAGGCCCGCGCCCGGCGCTGCCCCTCGGGGGCCCGGGCCCGCTGGGCGAGTTCCTGCCTCCACCC GAGTGCCCGGTCTTCGAACCCAGCTGGGAAGAGTTCGCGGACCCCTTCGCTTTCATCCACAAGATCCGGCCCATAGCCGAGCAGACTGGC ATCTGTAAGGTGCGGCCGCCGCCGGGATTCTTCAGCAAGCGCCTGAAAGGCTCCATCAAGAGGACCAAAAGCCAGTCAAAGCTTGACAGA AACACGAGCTTTCGGCTTCCATCCCTTCGCAGTACAGATGACAGGTCTCGTGGGCTGCCTAAACTAAAAGAGTCACGTTCCCATGAATCC TTGCTGAGCCCATGCAGCACAGTGGAATGTCTGGATCTTGGTAGAGGGGAACCTGTATCAGTGAAACCACTTCATAGTAGCATCCTTGGA CAAGACTTCTGCTTTGAGGTTACCTACTTAAGTGGAAGTAAATGCTTCAGCTGTAATTCTGCTTCTGAGAGAGACAAGTGGATGGAAAAC CTTCGCAGGACAGTTCAACCTAATAAGGACAATTGCAGGCGAGCTGAAAATGTTCTTCGTTTATGGATCATTGAAGCCAAGGACCTTGCC CCTAAAAAGAAATATTTCTGCGAACTGTGCCTTGATGATACCCTCTTTGCTCGTACAACCAGCAAGACCAAAGCAGACAATATTTTCTGG GGCGAACATTTTGAATTCTTCAGCCTTCCACCTCTTCATAGTATCACAGTTCACATTTACAAGGATGTGGAAAAAAAGAAAAAAAAGGAC AAGAATAATTATGTAGGGCTAGTCAACATCCCCACTGCCAGTGTGACTGGTCGCCAATTTGTAGAAAAGTGGTATCCAGTGAGTACACCT ACACCCAACAAAGGAAAGACAGGAGGACCTTCTATTCGGATTAAATCACGTTTCCAAACTATCACCATTCTGCCTATGGAGCAATACAAA GAATTTGCAGAATTTGTCACCAGCAACTACACCATGCTGTGTTCTGTCCTTGAGCCAGTAATTAGTGTGAGAAATAAAGAGGAGTTGGCT TGTGCCTTAGTGCACATTCTTCAAAGTACTGGCAGAGCCAAGGATTTTCTGACTGACTTGGTGATGTCTGAGGTGGATCGTTGTGGAGAG CATGATGTCTTGATCTTCAGAGAGAACACTATTGCCACCAAATCCATTGAGGAATACCTCAAGTTGGTGGGACAACAGTATCTTCATGAC GCACTGGGGGAGTTTATCAAAGCTTTGTATGAGTCCGATGAGAACTGTGAAGTGGATCCCAGCAAATGTTCATCTAGTGAACTGATAGAC CATCAGAGCAACCTGAAAATGTGCTGTGAGCTGGCTTTCTGCAAGATCATCAACTCTTACTGTGTTTTCCCTCGTGAGTTGAAAGAAGTG TTTGCATCATGGAAGCAGCAGTGCCTGAACCGTGGCAAGCAAGACATCAGCGAGAGGCTCATCAGTGCCTCATTATTTCTCCGTTTTCTG TGTCCAGCCATTATGTCTCCCAGTCTTTTCAACCTTATGCAGGAGTATCCTGATGACCGCACATCTCGGACTCTAACTCTTATTGCCAAG GTCATTCAGAACCTGGCCAACTTTGCCAAGTTTGGTAACAAAGAGGAATACATGGCATTCATGAATGATTTTTTAGAACATGAATGGGGT GGAATGAAGCGCTTTCTTTTGGAGATCTCTAATCCAGACACCATCTCAAACACCCCAGGCTTTGATGGTTACATTGATCTGGGCCGAGAG CTTTCAGTTTTGCATTCCTTACTGTGGGAAGTAGTTTCCCAACTTGATAAGGCGACCGTGGCAAAATTGGGGCCTCTCCCTCGTGTTCTT GCTGATATTACCAAGTCATTGACTAATCCTACGCCAATACAACAGCAACTGAGACGCTTCACTGAACATAACTCCAGTCCAAATGTCAGT GGAAGCCTCTCCTCTGGGCTGCAGAAAATATTTGAAGACCCCACTGACAGTGATTTGCATAAACTAAAATCTCCAAGCCAGGACAACACA GACAGCTACTTCAGAGGGAAAACATTATTGCTGGTTCAGCAAGCCTCCTCTCAGAGCATGACTTATTCTGAAAAGGATGAAAGGGAAAGT AGCCTTCCTAATGGTCGGAGCGTCTCCCTCATGGACCTCCAGGACACTCATGCTGCTCAAGTGGAGCATGCATCTGTCATGCTTGATGTG CCTATACGCTTGACCGGAAGCCAGCTTTCCATAACCCAGGTGGCCAGCATCAAACAGCTGCGGGAAACCCAGAGCACTCCCCAAAGTGCA CCCCAAGTGAGAAGGCCCCTGCACCCAGCCTTGAACCAGCCAGGTGGCCTTCAGCCCTTGTCGTTCCAGAACCCTGTCTATCACCTCAAT AACCCAATTCCAGCAATGCCAAAGGCCTCTATAGATTCCAGTTTGGAGAACCTAAGCACTGCCAGTTCCAGAAGCCAAAGTAACAGTGAA GACTTCAAGCTCAGTGGACCCAGCAATAGCAGCATGGAAGATTTCACTAAACGTAGCACTCAGAGTGAGGACTTCTCCAGGCGGCACACG GTGCCAGATAGACACATACCTCTTGCTTTGCCACGACAAAATAGTACTGGGCAGGCCCAGATCCGAAAAGTGGACCAGGGTGGGTTAGGT GCCCGAGCCAAAGCCCCACCATCCCTGCCACACAGTGCTTCTTTACGTAGCACCGGGAGCATGTCAGTGGTGTCCGCAGCCCTGGTGGCC GAACCTGTGCAGAATGGGAGCCGGTCCCGGCAGCAGTCCTCTTCCTCCAGAGAGAGCCCTGTTCCCAAAGTTAGAGCAATCCAGAGACAA CAGACACAGCAGGTTCAGTCACCTGTGGACTCTGCCACAATGTCCCCAGTAGAGAGGACAGCAGCCTGGGTTCTGAACAATGGGCAGTAT GAAGAGGATGTGGAAGAAACTGAGCAAAATCTAGATGAAGCCAAGCATGCTGAGAAGTATGAACAAGAAATTACTAAACTGAAGGAGCGC CTGAGAGTTTCCAGCCGGCGACTGGAGGAATATGAACGCCGCTTGCTGGTGCAGGAGCAGCAGATGCAGAAGCTGCTGCTGGAATACAAG GCCCGACTGGAGGACAGCGAGGAGCGGCTCCGAAGACAGCAGGAAGAAAAAGATAGCCAGATGAAAAGCATCATCAGCAGGCTAATGGCT GTGGAAGAGGAACTGAAGAAGGATCATGCTGAGATGCAAGCAGTTATTGATGCAAAGCAGAAAATAATTGATGCACAGGAAAAACGGATC GTGTCCCTGGATTCAGCCAACACCAGACTGATGAGCGCGCTGACCCAAGTGAAGGAGCGGTACAGCATGCAGGTCCGCAATGGCATCTCC |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_KDM5B_ENST00000367265_chr1_202777230_-_RASAL2_ENST00000448150_chr1_178389646_+_10939nt TTCAGTCTGTTGAAGGATACCCCGTTGTGTATTTCTACCTGTATGTACCAGAGACACCTCAAATTCAAAATGTCCAGAAATGAACACAGT ATCTTCTTCCCTTGAGTAACTCGCCTTCTGTATATAATTGGGGTGAATGTTCCAGCAATGCCAACGGGCTAGCATCTACTCAGGCAGGTA CGCCAGACATCTGAATCTTAATACCTCGTCGTCCCCCCTCAATCTGTCACTATGTCCTAATTTTATTTCCTACCTTTGCATCCCTTCCTC ATAATTATCAGCACCACTGCCTTAATTTAGATCCTATCATTCCTTGTCTGGATTATTTCAAGTCTTTCGCCCCTCTCAAGTCTGACCTCG TCATAGACTGTTTGTGGATGATTATTTTCCCTGCAACATCTCCACCTCCCAATAGTCTCCATCACTTATTAGCCATGTGAATTATGGCAA ATTGCTTAACCTACCTATGCCTCACTTTCCTTATTGTAAAGTGGAAATAAGAGTACCTATCTCATAGGGTTGTGTGATTAATCATGCGAT GCAATTAGAACAGTGCCTAGGATATGAAAGTGCCCCAAAATGTTACGTTATTATTATTATTACTACTATTGCCTTCTCATGAACATGCTA TGTGTATGTTCAAGCTGTTATCTCTACTGGAAAATCCTTCTCCGTTTCCAATACTCTTTCCAAAACCCCCTCCTGGGTTTTACTGCACCT ACCATTGTGTACTGACGTGATTGAATGATTGGCTTATGGGACTGATCCTTTCTACCAGACTTAACTTCTTCAGGGCAGGAACTCTGATAC ATAGTAAATGGTCAATAAAAGTTGGCTCAACTGAAACCCTAAGGATAAACTCCATCCACAGCGGAAGGCGCGGCCCCGCCCGATTCGGGG GCGGGGCGGGGAGCCGCGCGCGGAGGGTGGGTCGATGGGGGTGGGGTGGGACTCTTTTTCCTCGCCGTGGCGGCGGAGGCGCACGGCGTG GGCTTGCGGCGAGACGTCGTCGTCGGAGGCTGAAAAAGCCCAAGGTGCTGCCGTTGCCCGTACAACTCGGACTTGCTGTTGCTCGAGCCG CGTCTGCACGGGTCTCGGACCGAGCGGAGCTCGCAGCCTCGGTCCCGGAGCCCACCTTCGCCTCGCCCTTGCCCAGCCTGCGGTGATGGA GGCGGCCACCACACTGCACCCAGGCCCGCGCCCGGCGCTGCCCCTCGGGGGCCCGGGCCCGCTGGGCGAGTTCCTGCCTCCACCCGAGTG CCCGGTCTTCGAACCCAGCTGGGAAGAGTTCGCGGACCCCTTCGCTTTCATCCACAAGATCCGGCCCATAGCCGAGCAGACTGGCATCTG TAAGGTGCGGCCGCCGCCGGGATTCTTCAGCAAGCGCCTGAAAGGCTCCATCAAGAGGACCAAAAGCCAGTCAAAGCTTGACAGAAACAC GAGCTTTCGGCTTCCATCCCTTCGCAGTACAGATGACAGGTCTCGTGGGCTGCCTAAACTAAAAGAGTCACGTTCCCATGAATCCTTGCT GAGCCCATGCAGCACAGTGGAATGTCTGGATCTTGGTAGAGGGGAACCTGTATCAGTGAAACCACTTCATAGTAGCATCCTTGGACAAGA CTTCTGCTTTGAGGTTACCTACTTAAGTGGAAGTAAATGCTTCAGCTGTAATTCTGCTTCTGAGAGAGACAAGTGGATGGAAAACCTTCG CAGGACAGTTCAACCTAATAAGGACAATTGCAGGCGAGCTGAAAATGTTCTTCGTTTATGGATCATTGAAGCCAAGGACCTTGCCCCTAA AAAGAAATATTTCTGCGAACTGTGCCTTGATGATACCCTCTTTGCTCGTACAACCAGCAAGACCAAAGCAGACAATATTTTCTGGGGCGA ACATTTTGAATTCTTCAGCCTTCCACCTCTTCATAGTATCACAGTTCACATTTACAAGGATGTGGAAAAAAAGAAAAAAAAGGACAAGAA TAATTATGTAGGGCTAGTCAACATCCCCACTGCCAGTGTGACTGGTCGCCAATTTGTAGAAAAGTGGTATCCAGTGAGTACACCTACACC CAACAAAGGAAAGACAGGAGGACCTTCTATTCGGATTAAATCACGTTTCCAAACTATCACCATTCTGCCTATGGAGCAATACAAAGAATT TGCAGAATTTGTCACCAGCAACTACACCATGCTGTGTTCTGTCCTTGAGCCAGTAATTAGTGTGAGAAATAAAGAGGAGTTGGCTTGTGC CTTAGTGCACATTCTTCAAAGTACTGGCAGAGCCAAGGATTTTCTGACTGACTTGGTGATGTCTGAGGTGGATCGTTGTGGAGAGCATGA TGTCTTGATCTTCAGAGAGAACACTATTGCCACCAAATCCATTGAGGAATACCTCAAGTTGGTGGGACAACAGTATCTTCATGACGCACT GGGGGAGTTTATCAAAGCTTTGTATGAGTCCGATGAGAACTGTGAAGTGGATCCCAGCAAATGTTCATCTAGTGAACTGATAGACCATCA GAGCAACCTGAAAATGTGCTGTGAGCTGGCTTTCTGCAAGATCATCAACTCTTACTGTGTTTTCCCTCGTGAGTTGAAAGAAGTGTTTGC ATCATGGAAGCAGCAGTGCCTGAACCGTGGCAAGCAAGACATCAGCGAGAGGCTCATCAGTGCCTCATTATTTCTCCGTTTTCTGTGTCC AGCCATTATGTCTCCCAGTCTTTTCAACCTTATGCAGGAGTATCCTGATGACCGCACATCTCGGACTCTAACTCTTATTGCCAAGGTCAT TCAGAACCTGGCCAACTTTGCCAAGTTTGGTAACAAAGAGGAATACATGGCATTCATGAATGATTTTTTAGAACATGAATGGGGTGGAAT GAAGCGCTTTCTTTTGGAGATCTCTAATCCAGACACCATCTCAAACACCCCAGGCTTTGATGGTTACATTGATCTGGGCCGAGAGCTTTC AGTTTTGCATTCCTTACTGTGGGAAGTAGTTTCCCAACTTGATAAGGGTGAAAATTCCTTCCTACAGGCGACCGTGGCAAAATTGGGGCC TCTCCCTCGTGTTCTTGCTGATATTACCAAGTCATTGACTAATCCTACGCCAATACAACAGCAACTGAGACGCTTCACTGAACATAACTC CAGTCCAAATGTCAGTGGAAGCCTCTCCTCTGGGCTGCAGAAAATATTTGAAGACCCCACTGACAGTGATTTGCATAAACTAAAATCTCC AAGCCAGGACAACACAGACAGCTACTTCAGAGGGAAAACATTATTGCTGGTTCAGCAAGCCTCCTCTCAGAGCATGACTTATTCTGAAAA GGATGAAAGGGAAAGTAGCCTTCCTAATGGTCGGAGCGTCTCCCTCATGGACCTCCAGGACACTCATGCTGCTCAAGTGGAGCATGCATC TGTCATGCTTGATGTGCCTATACGCTTGACCGGAAGCCAGCTTTCCATAACCCAGGTGGCCAGCATCAAACAGCTGCGGGAAACCCAGAG CACTCCCCAAAGTGCACCCCAAGTGAGAAGGCCCCTGCACCCAGCCTTGAACCAGCCAGGTGGCCTTCAGCCCTTGTCGTTCCAGAACCC TGTCTATCACCTCAATAACCCAATTCCAGCAATGCCAAAGGCCTCTATAGATTCCAGTTTGGAGAACCTAAGCACTGCCAGTTCCAGAAG CCAAAGTAACAGTGAAGACTTCAAGCTCAGTGGACCCAGCAATAGCAGCATGGAAGATTTCACTAAACGTAGCACTCAGAGTGAGGACTT CTCCAGGCGGCACACGGTGCCAGATAGACACATACCTCTTGCTTTGCCACGACAAAATAGTACTGGGCAGGCCCAGATCCGAAAAGTGGA CCAGGGTGGGTTAGGTGCCCGAGCCAAAGCCCCACCATCCCTGCCACACAGTGCTTCTTTACGTAGCACCGGGAGCATGTCAGTGGTGTC CGCAGCCCTGGTGGCCGAACCTGTGCAGAATGGGAGCCGGTCCCGGCAGCAGTCCTCTTCCTCCAGAGAGAGCCCTGTTCCCAAAGTTAG AGCAATCCAGAGACAACAGACACAGCAGGTTCAGTCACCTGTGGACTCTGCCACAATGTCCCCAGTAGAGAGGACAGCAGCCTGGGTTCT GAACAATGGGCAGTATGAAGAGGATGTGGAAGAAACTGAGCAAAATCTAGATGAAGCCAAGCATGCTGAGAAGTATGAACAAGAAATTAC TAAACTGAAGGAGCGCCTGAGAGTTTCCAGCCGGCGACTGGAGGAATATGAACGCCGCTTGCTGGTGCAGGAGCAGCAGATGCAGAAGCT GCTGCTGGAATACAAGGCCCGACTGGAGGACAGCGAGGAGCGGCTCCGAAGACAGCAGGAAGAAAAAGATAGCCAGATGAAAAGCATCAT CAGCAGGCTAATGGCTGTGGAAGAGGAACTGAAGAAGGATCATGCTGAGATGCAAGCAGTTATTGATGCAAAGCAGAAAATAATTGATGC ACAGGAAAAACGGATCGTGTCCCTGGATTCAGCCAACACCAGACTGATGAGCGCGCTGACCCAAGTGAAGGAGCGGTACAGCATGCAGGT CCGCAATGGCATCTCCCCCACCAACCCCACCAAGCTTTCCATCACGGAGAATGGTGAATTCAAAAACAGCAGCTGCTGACGGGCTTTGTC TGTGGAAGGAGACAGAAGGAAATTGACCCACTCTCCTATCTCCAGACCTTTACCTAGCCCCTCCAGGTTTACAGAATGTTGCTACTTCAC AATGGCGATGTGGTGAGAAACTCCTGAATGAAGAAAGGAACCTTGTCTTTCAGGGCATAAGGCGGCGACTTCCAAGGTCAATGCTTTTCC CCCACATCTCTATGTACATAGGGAACTTAGTTCTGGGCCATGTACAGAAAATATCACTGTAATATACCAAAAGGAAGTTAATAATGTAGA TTACCTTTTTGATTATTGCTATTTTTATTATTGTTTTCCTCTTGTTGAAAGCACTGCAGTTGTTACAGGAAGTAAAGTAGGAACTGTTGT GTGAGCGAGACATGAGCCTGTAGGTTCAGTAGGTAGAGACCAAGCATCTATCTGATAGAAGCACATGGAGTGCAATAGGACATTGTGAGA AGGAATTTTTCAGGGATTCATCTACTAGTTTAAAAACCCCACTCTGGCCCTCTTGTCCTTTCAGAAAACATGCAAATACCAAGATCCATA CAAAACAATAATTTATTCCACTGATCAACCAAGACTGGTTCTGGTTGGACAGCTAATCTGATTTGGGGATTCACTGTTTCAGAGGACACA GACAAAAGCTGTTGCATCAAAACTGGACTTTAGGAGTAATTTCTATTGAACTCCTGTCAATATGTTTATTTCCTCTGTCTACAGCAGATG GGAGTCTTCTCTTTTAGACAGGGGCTTTTTGTTTTTAACCCCAATTGTAATAAAGGGTGTTCTTTTTCCTCTTTAGAGTTTACAAAACTA TAAATATTTGTGTCTCCACATACCATCTTCATCTTCACACATTCACTGTGCTTTCCTCCCCATAGTGGGAGCTGTCATCACCAACAGGGT TTACTCTCCCCTGGAGAGGTTATTTAAATAGCTGTCCATAAGCCATCCAGATCAACACCCTTTCTTCCATACAGAAAAGGGCTAACCATA CCACAGCTGGAATCTCTGAATATTTCCTATTAAAAATTTTTTCTATGTGTTGTTATAATTTTTGTTTGGGATAAAGACTCTATCCATTGT ACTAGCAAATCTATGGGGGGTAATTTTATCTCCATCTTTAACTTTTAAAGTACTTCTTCCCCTTATCCCCTCAATAAAGAAAGGAAATCC AAATTTGAAGCATCACTCTCTTAAAAGAAAAAGAAAATAATGGAAAGTGTCAGGATGGCACATTCCAGTTATTATTCCAATGCTCGTAGA TCTGACAATAATGACCCAATTTCAACACTTGTCATCCATAGCCTTATTATTATAGAACAGAAAAAGTCATGGAAACGAATTCATTTCCTT TTTTCCAGAGGTGTGCAATGTCATCTTGAATGCAACCTTGATTACCAGAAGTATGGAAGGTTACATGTTAAACAGACATTATATATACAA ATATATATATAATATATATTCACACATATGTACATATAACTGCACAAATAGGAAAAGTTCATGCCTTCTATGCTGTTCAGATATAATGTT AAAAGGGTCTCAAACCTCTTTAAGCAAGATCTAAGTAGTTGTTTTATATTGAGAAAGCAACAATGTTTCTCGAATAAGTTGATGTTGATT TTAAATTATAAGCTTTAAAGAATTTTTTTTCTAGAAAAAGGGGATGGAAAAAAAAGGACCTGAGGGAGCCATATGCATCAAGTGAGTGTT TCTCCATAACAGAATATTTATAAGAGAACATGTATAGTGCCCTCTTTTGAGTGATGCCGACAGACACCAAGCCCTCCTTTTCACCAAGTC CCAGGCTTGCATTCCAGCCTCTTGAGCTCTGCCCTCTCTCAGGTGGATCTTTGTGTTGGACCTTACGTTTCAGCAACCTCACCATGGCCA CATAACCCACAACCTTTTAAAACAGTTTCTTTCATAGCAATCCCTGTTTCTGCCAGACAGATCTAAAATGGGAGTTTCTCACTGTGTTTA TCTGATCTGCACACTTTATATCCAGCTGTTTTGGCACTTTTACGTTTTCTTCACCTTTGGTTTTGGTTTGCAAATTCTTACACCTTCTCT CCAAGCGGAGGGCACACTGTGGTCAAAATCACTTATTTTATTAGGAAAAAGAGGTAACTGTTCCAAAGTGTAGTGTCCTTTGTTGAAGGA GGAGGGATGTAAGCATAGATTTGTTCTTGTTTCTGGCTATTCTCAGCTCAAGCCATGTTTAATTCATTCTTTGTAAAAGCCTTCAATTGT GCCACAGAAAACCTGGTAAGAGAATTGTCAGTTTCATTGGCCATAAGTATGTAATGTGGGTGATGTCTTGCCATTGAGGTTTGGAAGCTC TTAAGTGCCGATTATGGATTACAGAGGGCTGATAAAATTACTTATATTGGGAATTGAGAGAAGCCCCAAAAAATCAAATGTGCTTTTGAT GGATAGAGTGTATCTTATTAGCATTATGGGAGCTCCTTAGAGGGCTGTCTTCACTGAAAGATTTAATGCCCAAAACATTTGGACAGATTA TGCAGCCTTCTACTACCAGGTTATCTTGAATGAAGAAGAAATAGTAAAAAATAATAATAATAGAGCATTACCAATAAGCTAAAAGTTCAG AGTTGCTGATAGATGTTAAATGTTAAGTTATCCTGTGAGCCTACTCCTGTCCAACCTTTTTTCTCAGTATTTCTTTAGAGAATGCTGCAA TCTGTATAAGTTACTCTGAAGGATTTTTTAAGAAGAGAAGCCACCAACAGGTGATAATTTTTATGGAGATGTTTCTTAATTGGCTTTCCC TCAGTTCAAGTAGGTAAATAACTTTGTTTGCTGGGAGGAGGTACATGGCTGAAGAGAGGCAAATAGATTAAGATAGCAATGTCTTGCACT TCCTGTTTCCCTCAAAACAACACCACATTGTGGGGCGCAGGATAGATCAGGGTTGAGTGGAATTTGGAATTCAGGTGAAGTGCTTGTAAA GTGCATGTCTAGCTGACAACAGACTTGACCATTAATGAGGACAGTGTTGGTAGGAGTCAGAAAAGAGCTTCATATTCCCCTTTTATATTA CTGAAGCAATAAGCAATCTGAGCTGAAGCAGCAAAAAGAGTCACATTTCCATCAGGTCATCATATTCCCTGAGTCTCTGCAGCAAAAGCC ATGTCAGAGGGGAGATTATAACTAGGTAACTATAACAAGCACTTGAGCACTTACCATGTTCCAAGCACTATCACCAAGGTACTGTTGGGG TTTATGGCAGTCTAACGGTAAGAAAAATGTGGTAAAATGAGGTAATCATGCTGCTATAGCTTTTTGCTTTTTTTCATATAGTATCAAGTT GGTCAGAATTAGCTTTCTCTGACTGGTCTGCTTCCGTGTTTCTCTGTGATGGTGTTAAGATTATGAAAGAAAAAGAAGATTACCTAAGAC TGCTACAAGTGTTAACTATATGCCCTTAAGAATGAGCTTGACTTTGGAAGTAAAGCTTTTCAGATCTTAGTCTACCCGGGGCCTTTGTTG ATGGGTCTGTGGTTCTGTAGACCCCTGGCTTTCACTGTGTTCTCAGAGGTACACCAGATTGAGAGCAGAGTTCTTCTTTGGAAGTCCCAG AGCAAAATAACTGCCATCAAGTGAGTTTGCATTCGTATTTGTTTCCCCTTCCATAGAGGGTTAGTTTTAGTTACCTCTAGCTTGGAGTTC CTGAGAAGGCTGGTTATAGGACTGAGCGTGGGAAAGGAACCCTCTTCAGGATTACCTCAGTCCCATCAGTCTACCCCATTGTGACATTGA GCCCAACACACACGCTTGACACCAGACTAGACTTGTCACAGGGCCAAACCCAACAGCCACATGCCATAGCTTCACTGCATTTTCAGCTAC ACCTTTGGAGGCCACCTTCTCCTATCAACTGTGGAAAGCCAGAAGGGCTCCCTTCTCCATTCTCCTTCCCTTTTTCAAGTCTAATAGTGA AATCTCCTGCTTACCCCAGCAGTAAATAGTTGCCTTCCTACCCCTTACCTGGGGGCCGATAATTTGAGATACTTTGTTTTTTCAATGCGT CAGTTGAAGGATTTAGTTTCTTAAAAGCAAGAAATGTTGGAGTGTTGAATTTTTAAATAGAATCTCTTTTCATGTTTGAATGATTGTTAT TAGTTCTAGAAGCATTCTCTTTGTCATGACCCGATTATGTATACTCTTGGGTTTAGGAAGGACAAAAGTGATGAAATTTGCATGAGATAG AATAAATATCTTAGGAGGAGTGAAAGAACCTGAGGAAGAGACACGACCCTAAGGGAATGAATGCATAAGCAGTCTTCTCAGTAGCCCAGA GTTTCCAGGAAACAGGAATATTTATATCCCTTGCCCACTCTTAAAATACATAGATACATAAAAAGGCAGTCTCTGTAGACAACACATGCA CACACCCACACAAAACATAATTCCTGGGGCTTCCTTTTTCTGAATGTTAATCCATTTTATCGAGCAGTGATTCCCAAACTTTGAGATTTT CAGATTTTATGCTCTCGTCTGTTAGATTTTATGACATTCTATCATCCTAAAAAATGTACTATATGTGTTATATGTATATATAAGTTAAAG CAACTTGAAATTGACTTGGTTTGGCATTGTCTCAAGAACCCTAGATATCATTATTGATACCATGGGGAATCATAGAAATAAAGTTGAATA TCATTGATCTGAGAGTAGGATCCAGAAATAAGTAGTTTCAGTTCCTGATCAGTTAAGCCTCAAGTGTTTGAGTAACCAACACAGCAAGAC TTGGGAAATGCAGTGAGCACCCGAGGAAAGGAAAGTGGTAGTCTTTGCCTGCATTTCAGCATGCATTTTCCTTTCCTACTCAGTTGCTAT CTTCCACTTAAATACCCTCATTTGACCCTAGGAAGTTTTTTGTTTTTTTTTTTAGTTTGAGACTTAAAACCAGATTTATTTGTTGTTGTA GAGAGATTTCCACAGAAGTTGTGTTTTAGGGACCTCCATCATCTTTGTGGGGGTACAGATATTTATGTGTAAATATCATTTTATGTGATT TCCAAATTTTCGAGGGAAACATTTCAATTCCCAGTTCAACAAAAGGTTAAATACTAATTGACTCAATGACCACCTTCAGGAAAGTTAAAT AGTAAATTAGGTTAAATTTTGACTGGTGCTTAGACATTTCCTAGTTATATTAACTTAAGCAGACAGCAGCACATTAACCTGAGTTACACC TGTGAGGAAATGACCTTCTAAATTTGATTTTGTTTTTCATCTCCAGGGCCTTAATAAGAGTGTGTTAACACACGACTATTTTACAATGAT AGCTCTAAATAATTTATTTTTTATTTCAAGAAAGAGAAATACACCTTAGAAAAACAAAACCCAAGATTTTATTTTATTTTTAAAGCCATA TTTTTGTGCTAGTAGCATTTAGATTATTCCGTATGTGAGATCCGTATCAGCATTTCATTACCTGGGTTTGTTCTAAAGAAGATTTATTTT TGTTCTGTGAATAATTTTTGACAGTTCTTGTACATGTACAGATATAGATACGTTTGAGGTCTTTTATTGATATTCCTACAAAGAATACAA ATAAACTTTAACTTTAAACATTTCAGACTAAAGTTGCTACTATATTTGACATATTGCTGTCTTCTAGCATGCACCTGGGTGACTAGGACA CTTGAAGAGAAACAAGAAAGGAAATGTATGCCGGAATATTCTTCTAAAAATATATTTTAACATTAAGAACAGTCTGTCCTAGAATTTCCC AACTTCCATGTAATAAGATTTCAATTTAGGAAAAATAACTAGCATTAGCATGTATTGTGATAAAACTGTTACTTTCGAATTCTGCAGAAT TTGAAATCTCTTTAATAACTTGTGACAGGTAAAGAAAGTTTCATCTGGTTTATTAGGAAATGTAGCCCCACTTAGCTTCCTAGACCACTA CCATCCTCTTGTAATTTTCCAGTTAGATTAATGGGGTTTGTTTTCAGGATTTTTGATGTTTGGTTCAGGTTTTTTATTTTAATTTCTTAA TAGAAGTTCATTTGTCATTCCCAACATGATTGTTCCCAAATACACCCATCTTCTCCTGCATCCCTGTTTCATTCTGTAAAATCCAGGGAT GCAGGTTTCATGTGTAGTCTTGTTTTGTGTTAGTTGTAGGTCTGTGCTTTTTGGCACATGTCGAGTTCTTCCTAATCTTGTTCTACTAGG >In-frame_KDM5B_ENST00000367265_chr1_202777230_-_RASAL2_ENST00000367649_chr1_178389646_+_4831nt TTCAGTCTGTTGAAGGATACCCCGTTGTGTATTTCTACCTGTATGTACCAGAGACACCTCAAATTCAAAATGTCCAGAAATGAACACAGT ATCTTCTTCCCTTGAGTAACTCGCCTTCTGTATATAATTGGGGTGAATGTTCCAGCAATGCCAACGGGCTAGCATCTACTCAGGCAGGTA CGCCAGACATCTGAATCTTAATACCTCGTCGTCCCCCCTCAATCTGTCACTATGTCCTAATTTTATTTCCTACCTTTGCATCCCTTCCTC ATAATTATCAGCACCACTGCCTTAATTTAGATCCTATCATTCCTTGTCTGGATTATTTCAAGTCTTTCGCCCCTCTCAAGTCTGACCTCG TCATAGACTGTTTGTGGATGATTATTTTCCCTGCAACATCTCCACCTCCCAATAGTCTCCATCACTTATTAGCCATGTGAATTATGGCAA ATTGCTTAACCTACCTATGCCTCACTTTCCTTATTGTAAAGTGGAAATAAGAGTACCTATCTCATAGGGTTGTGTGATTAATCATGCGAT GCAATTAGAACAGTGCCTAGGATATGAAAGTGCCCCAAAATGTTACGTTATTATTATTATTACTACTATTGCCTTCTCATGAACATGCTA TGTGTATGTTCAAGCTGTTATCTCTACTGGAAAATCCTTCTCCGTTTCCAATACTCTTTCCAAAACCCCCTCCTGGGTTTTACTGCACCT ACCATTGTGTACTGACGTGATTGAATGATTGGCTTATGGGACTGATCCTTTCTACCAGACTTAACTTCTTCAGGGCAGGAACTCTGATAC ATAGTAAATGGTCAATAAAAGTTGGCTCAACTGAAACCCTAAGGATAAACTCCATCCACAGCGGAAGGCGCGGCCCCGCCCGATTCGGGG GCGGGGCGGGGAGCCGCGCGCGGAGGGTGGGTCGATGGGGGTGGGGTGGGACTCTTTTTCCTCGCCGTGGCGGCGGAGGCGCACGGCGTG GGCTTGCGGCGAGACGTCGTCGTCGGAGGCTGAAAAAGCCCAAGGTGCTGCCGTTGCCCGTACAACTCGGACTTGCTGTTGCTCGAGCCG CGTCTGCACGGGTCTCGGACCGAGCGGAGCTCGCAGCCTCGGTCCCGGAGCCCACCTTCGCCTCGCCCTTGCCCAGCCTGCGGTGATGGA GGCGGCCACCACACTGCACCCAGGCCCGCGCCCGGCGCTGCCCCTCGGGGGCCCGGGCCCGCTGGGCGAGTTCCTGCCTCCACCCGAGTG CCCGGTCTTCGAACCCAGCTGGGAAGAGTTCGCGGACCCCTTCGCTTTCATCCACAAGATCCGGCCCATAGCCGAGCAGACTGGCATCTG TAAGGTGCGGCCGCCGCCGGGATTCTTCAGCAAGCGCCTGAAAGGCTCCATCAAGAGGACCAAAAGCCAGTCAAAGCTTGACAGAAACAC GAGCTTTCGGCTTCCATCCCTTCGCAGTACAGATGACAGGTCTCGTGGGCTGCCTAAACTAAAAGAGTCACGTTCCCATGAATCCTTGCT GAGCCCATGCAGCACAGTGGAATGTCTGGATCTTGGTAGAGGGGAACCTGTATCAGTGAAACCACTTCATAGTAGCATCCTTGGACAAGA CTTCTGCTTTGAGGTTACCTACTTAAGTGGAAGTAAATGCTTCAGCTGTAATTCTGCTTCTGAGAGAGACAAGTGGATGGAAAACCTTCG CAGGACAGTTCAACCTAATAAGGACAATTGCAGGCGAGCTGAAAATGTTCTTCGTTTATGGATCATTGAAGCCAAGGACCTTGCCCCTAA AAAGAAATATTTCTGCGAACTGTGCCTTGATGATACCCTCTTTGCTCGTACAACCAGCAAGACCAAAGCAGACAATATTTTCTGGGGCGA ACATTTTGAATTCTTCAGCCTTCCACCTCTTCATAGTATCACAGTTCACATTTACAAGGATGTGGAAAAAAAGAAAAAAAAGGACAAGAA TAATTATGTAGGGCTAGTCAACATCCCCACTGCCAGTGTGACTGGTCGCCAATTTGTAGAAAAGTGGTATCCAGTGAGTACACCTACACC CAACAAAGGAAAGACAGGAGGACCTTCTATTCGGATTAAATCACGTTTCCAAACTATCACCATTCTGCCTATGGAGCAATACAAAGAATT TGCAGAATTTGTCACCAGCAACTACACCATGCTGTGTTCTGTCCTTGAGCCAGTAATTAGTGTGAGAAATAAAGAGGAGTTGGCTTGTGC CTTAGTGCACATTCTTCAAAGTACTGGCAGAGCCAAGGATTTTCTGACTGACTTGGTGATGTCTGAGGTGGATCGTTGTGGAGAGCATGA TGTCTTGATCTTCAGAGAGAACACTATTGCCACCAAATCCATTGAGGAATACCTCAAGTTGGTGGGACAACAGTATCTTCATGACGCACT GGGGGAGTTTATCAAAGCTTTGTATGAGTCCGATGAGAACTGTGAAGTGGATCCCAGCAAATGTTCATCTAGTGAACTGATAGACCATCA GAGCAACCTGAAAATGTGCTGTGAGCTGGCTTTCTGCAAGATCATCAACTCTTACTGTGTTTTCCCTCGTGAGTTGAAAGAAGTGTTTGC ATCATGGAAGCAGCAGTGCCTGAACCGTGGCAAGCAAGACATCAGCGAGAGGCTCATCAGTGCCTCATTATTTCTCCGTTTTCTGTGTCC AGCCATTATGTCTCCCAGTCTTTTCAACCTTATGCAGGAGTATCCTGATGACCGCACATCTCGGACTCTAACTCTTATTGCCAAGGTCAT TCAGAACCTGGCCAACTTTGCCAAGTTTGGTAACAAAGAGGAATACATGGCATTCATGAATGATTTTTTAGAACATGAATGGGGTGGAAT GAAGCGCTTTCTTTTGGAGATCTCTAATCCAGACACCATCTCAAACACCCCAGGCTTTGATGGTTACATTGATCTGGGCCGAGAGCTTTC AGTTTTGCATTCCTTACTGTGGGAAGTAGTTTCCCAACTTGATAAGGCGACCGTGGCAAAATTGGGGCCTCTCCCTCGTGTTCTTGCTGA TATTACCAAGTCATTGACTAATCCTACGCCAATACAACAGCAACTGAGACGCTTCACTGAACATAACTCCAGTCCAAATGTCAGTGGAAG CCTCTCCTCTGGGCTGCAGAAAATATTTGAAGACCCCACTGACAGTGATTTGCATAAACTAAAATCTCCAAGCCAGGACAACACAGACAG CTACTTCAGAGGGAAAACATTATTGCTGGTTCAGCAAGCCTCCTCTCAGAGCATGACTTATTCTGAAAAGGATGAAAGGGAAAGTAGCCT TCCTAATGGTCGGAGCGTCTCCCTCATGGACCTCCAGGACACTCATGCTGCTCAAGTGGAGCATGCATCTGTCATGCTTGATGTGCCTAT ACGCTTGACCGGAAGCCAGCTTTCCATAACCCAGGTGGCCAGCATCAAACAGCTGCGGGAAACCCAGAGCACTCCCCAAAGTGCACCCCA AGTGAGAAGGCCCCTGCACCCAGCCTTGAACCAGCCAGGTGGCCTTCAGCCCTTGTCGTTCCAGAACCCTGTCTATCACCTCAATAACCC AATTCCAGCAATGCCAAAGGCCTCTATAGATTCCAGTTTGGAGAACCTAAGCACTGCCAGTTCCAGAAGCCAAAGTAACAGTGAAGACTT CAAGCTCAGTGGACCCAGCAATAGCAGCATGGAAGATTTCACTAAACGTAGCACTCAGAGTGAGGACTTCTCCAGGCGGCACACGGTGCC AGATAGACACATACCTCTTGCTTTGCCACGACAAAATAGTACTGGGCAGGCCCAGATCCGAAAAGTGGACCAGGGTGGGTTAGGTGCCCG AGCCAAAGCCCCACCATCCCTGCCACACAGTGCTTCTTTACGTAGCACCGGGAGCATGTCAGTGGTGTCCGCAGCCCTGGTGGCCGAACC TGTGCAGAATGGGAGCCGGTCCCGGCAGCAGTCCTCTTCCTCCAGAGAGAGCCCTGTTCCCAAAGTTAGAGCAATCCAGAGACAACAGAC ACAGCAGGTTCAGTCACCTGTGGACTCTGCCACAATGTCCCCAGTAGAGAGGACAGCAGCCTGGGTTCTGAACAATGGGCAGTATGAAGA GGATGTGGAAGAAACTGAGCAAAATCTAGATGAAGCCAAGCATGCTGAGAAGTATGAACAAGAAATTACTAAACTGAAGGAGCGCCTGAG AGTTTCCAGCCGGCGACTGGAGGAATATGAACGCCGCTTGCTGGTGCAGGAGCAGCAGATGCAGAAGCTGCTGCTGGAATACAAGGCCCG ACTGGAGGACAGCGAGGAGCGGCTCCGAAGACAGCAGGAAGAAAAAGATAGCCAGATGAAAAGCATCATCAGCAGGCTAATGGCTGTGGA AGAGGAACTGAAGAAGGATCATGCTGAGATGCAAGCAGTTATTGATGCAAAGCAGAAAATAATTGATGCACAGGAAAAACGGATCGTGTC CCTGGATTCAGCCAACACCAGACTGATGAGCGCGCTGACCCAAGTGAAGGAGCGGTACAGCATGCAGGTCCGCAATGGCATCTCCCCCAC CAACCCCACCAAGCTTTCCATCACGGAGAATGGTGAATTCAAAAACAGCAGCTGCTGACGGGCTTTGTCTGTGGAAGGAGACAGAAGGAA ATTGACCCACTCTCCTATCTCCAGACCTTTACCTAGCCCCTCCAGGTTTACAGAATGTTGCTACTTCACAATGGCGATGTGGTGAGAAAC >In-frame_KDM5B_ENST00000367264_chr1_202777230_-_RASAL2_ENST00000448150_chr1_178389646_+_9887nt CAACTCGGACTTGCTGTTGCTCGAGCCGCGTCTGCACGGGTCTCGGACCGAGCGGAGCTCGCAGCCTCGGTCCCGGAGCCCACCTTCGCC TCGCCCTTGCCCAGCCTGCGGTGATGGAGGCGGCCACCACACTGCACCCAGGCCCGCGCCCGGCGCTGCCCCTCGGGGGCCCGGGCCCGC TGGGCGAGTTCCTGCCTCCACCCGAGTGCCCGGTCTTCGAACCCAGCTGGGAAGAGTTCGCGGACCCCTTCGCTTTCATCCACAAGATCC GGCCCATAGCCGAGCAGACTGGCATCTGTAAGGTGCGGCCGCCGCCGGGATTCTTCAGCAAGCGCCTGAAAGGCTCCATCAAGAGGACCA AAAGCCAGTCAAAGCTTGACAGAAACACGAGCTTTCGGCTTCCATCCCTTCGCAGTACAGATGACAGGTCTCGTGGGCTGCCTAAACTAA AAGAGTCACGTTCCCATGAATCCTTGCTGAGCCCATGCAGCACAGTGGAATGTCTGGATCTTGGTAGAGGGGAACCTGTATCAGTGAAAC CACTTCATAGTAGCATCCTTGGACAAGACTTCTGCTTTGAGGTTACCTACTTAAGTGGAAGTAAATGCTTCAGCTGTAATTCTGCTTCTG AGAGAGACAAGTGGATGGAAAACCTTCGCAGGACAGTTCAACCTAATAAGGACAATTGCAGGCGAGCTGAAAATGTTCTTCGTTTATGGA TCATTGAAGCCAAGGACCTTGCCCCTAAAAAGAAATATTTCTGCGAACTGTGCCTTGATGATACCCTCTTTGCTCGTACAACCAGCAAGA CCAAAGCAGACAATATTTTCTGGGGCGAACATTTTGAATTCTTCAGCCTTCCACCTCTTCATAGTATCACAGTTCACATTTACAAGGATG TGGAAAAAAAGAAAAAAAAGGACAAGAATAATTATGTAGGGCTAGTCAACATCCCCACTGCCAGTGTGACTGGTCGCCAATTTGTAGAAA AGTGGTATCCAGTGAGTACACCTACACCCAACAAAGGAAAGACAGGAGGACCTTCTATTCGGATTAAATCACGTTTCCAAACTATCACCA TTCTGCCTATGGAGCAATACAAAGAATTTGCAGAATTTGTCACCAGCAACTACACCATGCTGTGTTCTGTCCTTGAGCCAGTAATTAGTG TGAGAAATAAAGAGGAGTTGGCTTGTGCCTTAGTGCACATTCTTCAAAGTACTGGCAGAGCCAAGGATTTTCTGACTGACTTGGTGATGT CTGAGGTGGATCGTTGTGGAGAGCATGATGTCTTGATCTTCAGAGAGAACACTATTGCCACCAAATCCATTGAGGAATACCTCAAGTTGG TGGGACAACAGTATCTTCATGACGCACTGGGGGAGTTTATCAAAGCTTTGTATGAGTCCGATGAGAACTGTGAAGTGGATCCCAGCAAAT GTTCATCTAGTGAACTGATAGACCATCAGAGCAACCTGAAAATGTGCTGTGAGCTGGCTTTCTGCAAGATCATCAACTCTTACTGTGTTT TCCCTCGTGAGTTGAAAGAAGTGTTTGCATCATGGAAGCAGCAGTGCCTGAACCGTGGCAAGCAAGACATCAGCGAGAGGCTCATCAGTG CCTCATTATTTCTCCGTTTTCTGTGTCCAGCCATTATGTCTCCCAGTCTTTTCAACCTTATGCAGGAGTATCCTGATGACCGCACATCTC GGACTCTAACTCTTATTGCCAAGGTCATTCAGAACCTGGCCAACTTTGCCAAGTTTGGTAACAAAGAGGAATACATGGCATTCATGAATG ATTTTTTAGAACATGAATGGGGTGGAATGAAGCGCTTTCTTTTGGAGATCTCTAATCCAGACACCATCTCAAACACCCCAGGCTTTGATG GTTACATTGATCTGGGCCGAGAGCTTTCAGTTTTGCATTCCTTACTGTGGGAAGTAGTTTCCCAACTTGATAAGGGTGAAAATTCCTTCC TACAGGCGACCGTGGCAAAATTGGGGCCTCTCCCTCGTGTTCTTGCTGATATTACCAAGTCATTGACTAATCCTACGCCAATACAACAGC AACTGAGACGCTTCACTGAACATAACTCCAGTCCAAATGTCAGTGGAAGCCTCTCCTCTGGGCTGCAGAAAATATTTGAAGACCCCACTG ACAGTGATTTGCATAAACTAAAATCTCCAAGCCAGGACAACACAGACAGCTACTTCAGAGGGAAAACATTATTGCTGGTTCAGCAAGCCT CCTCTCAGAGCATGACTTATTCTGAAAAGGATGAAAGGGAAAGTAGCCTTCCTAATGGTCGGAGCGTCTCCCTCATGGACCTCCAGGACA CTCATGCTGCTCAAGTGGAGCATGCATCTGTCATGCTTGATGTGCCTATACGCTTGACCGGAAGCCAGCTTTCCATAACCCAGGTGGCCA GCATCAAACAGCTGCGGGAAACCCAGAGCACTCCCCAAAGTGCACCCCAAGTGAGAAGGCCCCTGCACCCAGCCTTGAACCAGCCAGGTG GCCTTCAGCCCTTGTCGTTCCAGAACCCTGTCTATCACCTCAATAACCCAATTCCAGCAATGCCAAAGGCCTCTATAGATTCCAGTTTGG AGAACCTAAGCACTGCCAGTTCCAGAAGCCAAAGTAACAGTGAAGACTTCAAGCTCAGTGGACCCAGCAATAGCAGCATGGAAGATTTCA CTAAACGTAGCACTCAGAGTGAGGACTTCTCCAGGCGGCACACGGTGCCAGATAGACACATACCTCTTGCTTTGCCACGACAAAATAGTA CTGGGCAGGCCCAGATCCGAAAAGTGGACCAGGGTGGGTTAGGTGCCCGAGCCAAAGCCCCACCATCCCTGCCACACAGTGCTTCTTTAC GTAGCACCGGGAGCATGTCAGTGGTGTCCGCAGCCCTGGTGGCCGAACCTGTGCAGAATGGGAGCCGGTCCCGGCAGCAGTCCTCTTCCT CCAGAGAGAGCCCTGTTCCCAAAGTTAGAGCAATCCAGAGACAACAGACACAGCAGGTTCAGTCACCTGTGGACTCTGCCACAATGTCCC CAGTAGAGAGGACAGCAGCCTGGGTTCTGAACAATGGGCAGTATGAAGAGGATGTGGAAGAAACTGAGCAAAATCTAGATGAAGCCAAGC ATGCTGAGAAGTATGAACAAGAAATTACTAAACTGAAGGAGCGCCTGAGAGTTTCCAGCCGGCGACTGGAGGAATATGAACGCCGCTTGC TGGTGCAGGAGCAGCAGATGCAGAAGCTGCTGCTGGAATACAAGGCCCGACTGGAGGACAGCGAGGAGCGGCTCCGAAGACAGCAGGAAG AAAAAGATAGCCAGATGAAAAGCATCATCAGCAGGCTAATGGCTGTGGAAGAGGAACTGAAGAAGGATCATGCTGAGATGCAAGCAGTTA TTGATGCAAAGCAGAAAATAATTGATGCACAGGAAAAACGGATCGTGTCCCTGGATTCAGCCAACACCAGACTGATGAGCGCGCTGACCC AAGTGAAGGAGCGGTACAGCATGCAGGTCCGCAATGGCATCTCCCCCACCAACCCCACCAAGCTTTCCATCACGGAGAATGGTGAATTCA AAAACAGCAGCTGCTGACGGGCTTTGTCTGTGGAAGGAGACAGAAGGAAATTGACCCACTCTCCTATCTCCAGACCTTTACCTAGCCCCT CCAGGTTTACAGAATGTTGCTACTTCACAATGGCGATGTGGTGAGAAACTCCTGAATGAAGAAAGGAACCTTGTCTTTCAGGGCATAAGG CGGCGACTTCCAAGGTCAATGCTTTTCCCCCACATCTCTATGTACATAGGGAACTTAGTTCTGGGCCATGTACAGAAAATATCACTGTAA TATACCAAAAGGAAGTTAATAATGTAGATTACCTTTTTGATTATTGCTATTTTTATTATTGTTTTCCTCTTGTTGAAAGCACTGCAGTTG TTACAGGAAGTAAAGTAGGAACTGTTGTGTGAGCGAGACATGAGCCTGTAGGTTCAGTAGGTAGAGACCAAGCATCTATCTGATAGAAGC ACATGGAGTGCAATAGGACATTGTGAGAAGGAATTTTTCAGGGATTCATCTACTAGTTTAAAAACCCCACTCTGGCCCTCTTGTCCTTTC AGAAAACATGCAAATACCAAGATCCATACAAAACAATAATTTATTCCACTGATCAACCAAGACTGGTTCTGGTTGGACAGCTAATCTGAT TTGGGGATTCACTGTTTCAGAGGACACAGACAAAAGCTGTTGCATCAAAACTGGACTTTAGGAGTAATTTCTATTGAACTCCTGTCAATA TGTTTATTTCCTCTGTCTACAGCAGATGGGAGTCTTCTCTTTTAGACAGGGGCTTTTTGTTTTTAACCCCAATTGTAATAAAGGGTGTTC TTTTTCCTCTTTAGAGTTTACAAAACTATAAATATTTGTGTCTCCACATACCATCTTCATCTTCACACATTCACTGTGCTTTCCTCCCCA TAGTGGGAGCTGTCATCACCAACAGGGTTTACTCTCCCCTGGAGAGGTTATTTAAATAGCTGTCCATAAGCCATCCAGATCAACACCCTT TCTTCCATACAGAAAAGGGCTAACCATACCACAGCTGGAATCTCTGAATATTTCCTATTAAAAATTTTTTCTATGTGTTGTTATAATTTT TGTTTGGGATAAAGACTCTATCCATTGTACTAGCAAATCTATGGGGGGTAATTTTATCTCCATCTTTAACTTTTAAAGTACTTCTTCCCC TTATCCCCTCAATAAAGAAAGGAAATCCAAATTTGAAGCATCACTCTCTTAAAAGAAAAAGAAAATAATGGAAAGTGTCAGGATGGCACA TTCCAGTTATTATTCCAATGCTCGTAGATCTGACAATAATGACCCAATTTCAACACTTGTCATCCATAGCCTTATTATTATAGAACAGAA AAAGTCATGGAAACGAATTCATTTCCTTTTTTCCAGAGGTGTGCAATGTCATCTTGAATGCAACCTTGATTACCAGAAGTATGGAAGGTT ACATGTTAAACAGACATTATATATACAAATATATATATAATATATATTCACACATATGTACATATAACTGCACAAATAGGAAAAGTTCAT GCCTTCTATGCTGTTCAGATATAATGTTAAAAGGGTCTCAAACCTCTTTAAGCAAGATCTAAGTAGTTGTTTTATATTGAGAAAGCAACA ATGTTTCTCGAATAAGTTGATGTTGATTTTAAATTATAAGCTTTAAAGAATTTTTTTTCTAGAAAAAGGGGATGGAAAAAAAAGGACCTG AGGGAGCCATATGCATCAAGTGAGTGTTTCTCCATAACAGAATATTTATAAGAGAACATGTATAGTGCCCTCTTTTGAGTGATGCCGACA GACACCAAGCCCTCCTTTTCACCAAGTCCCAGGCTTGCATTCCAGCCTCTTGAGCTCTGCCCTCTCTCAGGTGGATCTTTGTGTTGGACC TTACGTTTCAGCAACCTCACCATGGCCACATAACCCACAACCTTTTAAAACAGTTTCTTTCATAGCAATCCCTGTTTCTGCCAGACAGAT CTAAAATGGGAGTTTCTCACTGTGTTTATCTGATCTGCACACTTTATATCCAGCTGTTTTGGCACTTTTACGTTTTCTTCACCTTTGGTT TTGGTTTGCAAATTCTTACACCTTCTCTCCAAGCGGAGGGCACACTGTGGTCAAAATCACTTATTTTATTAGGAAAAAGAGGTAACTGTT CCAAAGTGTAGTGTCCTTTGTTGAAGGAGGAGGGATGTAAGCATAGATTTGTTCTTGTTTCTGGCTATTCTCAGCTCAAGCCATGTTTAA TTCATTCTTTGTAAAAGCCTTCAATTGTGCCACAGAAAACCTGGTAAGAGAATTGTCAGTTTCATTGGCCATAAGTATGTAATGTGGGTG ATGTCTTGCCATTGAGGTTTGGAAGCTCTTAAGTGCCGATTATGGATTACAGAGGGCTGATAAAATTACTTATATTGGGAATTGAGAGAA GCCCCAAAAAATCAAATGTGCTTTTGATGGATAGAGTGTATCTTATTAGCATTATGGGAGCTCCTTAGAGGGCTGTCTTCACTGAAAGAT TTAATGCCCAAAACATTTGGACAGATTATGCAGCCTTCTACTACCAGGTTATCTTGAATGAAGAAGAAATAGTAAAAAATAATAATAATA GAGCATTACCAATAAGCTAAAAGTTCAGAGTTGCTGATAGATGTTAAATGTTAAGTTATCCTGTGAGCCTACTCCTGTCCAACCTTTTTT CTCAGTATTTCTTTAGAGAATGCTGCAATCTGTATAAGTTACTCTGAAGGATTTTTTAAGAAGAGAAGCCACCAACAGGTGATAATTTTT ATGGAGATGTTTCTTAATTGGCTTTCCCTCAGTTCAAGTAGGTAAATAACTTTGTTTGCTGGGAGGAGGTACATGGCTGAAGAGAGGCAA ATAGATTAAGATAGCAATGTCTTGCACTTCCTGTTTCCCTCAAAACAACACCACATTGTGGGGCGCAGGATAGATCAGGGTTGAGTGGAA TTTGGAATTCAGGTGAAGTGCTTGTAAAGTGCATGTCTAGCTGACAACAGACTTGACCATTAATGAGGACAGTGTTGGTAGGAGTCAGAA AAGAGCTTCATATTCCCCTTTTATATTACTGAAGCAATAAGCAATCTGAGCTGAAGCAGCAAAAAGAGTCACATTTCCATCAGGTCATCA TATTCCCTGAGTCTCTGCAGCAAAAGCCATGTCAGAGGGGAGATTATAACTAGGTAACTATAACAAGCACTTGAGCACTTACCATGTTCC AAGCACTATCACCAAGGTACTGTTGGGGTTTATGGCAGTCTAACGGTAAGAAAAATGTGGTAAAATGAGGTAATCATGCTGCTATAGCTT TTTGCTTTTTTTCATATAGTATCAAGTTGGTCAGAATTAGCTTTCTCTGACTGGTCTGCTTCCGTGTTTCTCTGTGATGGTGTTAAGATT ATGAAAGAAAAAGAAGATTACCTAAGACTGCTACAAGTGTTAACTATATGCCCTTAAGAATGAGCTTGACTTTGGAAGTAAAGCTTTTCA GATCTTAGTCTACCCGGGGCCTTTGTTGATGGGTCTGTGGTTCTGTAGACCCCTGGCTTTCACTGTGTTCTCAGAGGTACACCAGATTGA GAGCAGAGTTCTTCTTTGGAAGTCCCAGAGCAAAATAACTGCCATCAAGTGAGTTTGCATTCGTATTTGTTTCCCCTTCCATAGAGGGTT AGTTTTAGTTACCTCTAGCTTGGAGTTCCTGAGAAGGCTGGTTATAGGACTGAGCGTGGGAAAGGAACCCTCTTCAGGATTACCTCAGTC CCATCAGTCTACCCCATTGTGACATTGAGCCCAACACACACGCTTGACACCAGACTAGACTTGTCACAGGGCCAAACCCAACAGCCACAT GCCATAGCTTCACTGCATTTTCAGCTACACCTTTGGAGGCCACCTTCTCCTATCAACTGTGGAAAGCCAGAAGGGCTCCCTTCTCCATTC TCCTTCCCTTTTTCAAGTCTAATAGTGAAATCTCCTGCTTACCCCAGCAGTAAATAGTTGCCTTCCTACCCCTTACCTGGGGGCCGATAA TTTGAGATACTTTGTTTTTTCAATGCGTCAGTTGAAGGATTTAGTTTCTTAAAAGCAAGAAATGTTGGAGTGTTGAATTTTTAAATAGAA TCTCTTTTCATGTTTGAATGATTGTTATTAGTTCTAGAAGCATTCTCTTTGTCATGACCCGATTATGTATACTCTTGGGTTTAGGAAGGA CAAAAGTGATGAAATTTGCATGAGATAGAATAAATATCTTAGGAGGAGTGAAAGAACCTGAGGAAGAGACACGACCCTAAGGGAATGAAT GCATAAGCAGTCTTCTCAGTAGCCCAGAGTTTCCAGGAAACAGGAATATTTATATCCCTTGCCCACTCTTAAAATACATAGATACATAAA AAGGCAGTCTCTGTAGACAACACATGCACACACCCACACAAAACATAATTCCTGGGGCTTCCTTTTTCTGAATGTTAATCCATTTTATCG AGCAGTGATTCCCAAACTTTGAGATTTTCAGATTTTATGCTCTCGTCTGTTAGATTTTATGACATTCTATCATCCTAAAAAATGTACTAT ATGTGTTATATGTATATATAAGTTAAAGCAACTTGAAATTGACTTGGTTTGGCATTGTCTCAAGAACCCTAGATATCATTATTGATACCA TGGGGAATCATAGAAATAAAGTTGAATATCATTGATCTGAGAGTAGGATCCAGAAATAAGTAGTTTCAGTTCCTGATCAGTTAAGCCTCA AGTGTTTGAGTAACCAACACAGCAAGACTTGGGAAATGCAGTGAGCACCCGAGGAAAGGAAAGTGGTAGTCTTTGCCTGCATTTCAGCAT GCATTTTCCTTTCCTACTCAGTTGCTATCTTCCACTTAAATACCCTCATTTGACCCTAGGAAGTTTTTTGTTTTTTTTTTTAGTTTGAGA CTTAAAACCAGATTTATTTGTTGTTGTAGAGAGATTTCCACAGAAGTTGTGTTTTAGGGACCTCCATCATCTTTGTGGGGGTACAGATAT TTATGTGTAAATATCATTTTATGTGATTTCCAAATTTTCGAGGGAAACATTTCAATTCCCAGTTCAACAAAAGGTTAAATACTAATTGAC TCAATGACCACCTTCAGGAAAGTTAAATAGTAAATTAGGTTAAATTTTGACTGGTGCTTAGACATTTCCTAGTTATATTAACTTAAGCAG ACAGCAGCACATTAACCTGAGTTACACCTGTGAGGAAATGACCTTCTAAATTTGATTTTGTTTTTCATCTCCAGGGCCTTAATAAGAGTG TGTTAACACACGACTATTTTACAATGATAGCTCTAAATAATTTATTTTTTATTTCAAGAAAGAGAAATACACCTTAGAAAAACAAAACCC AAGATTTTATTTTATTTTTAAAGCCATATTTTTGTGCTAGTAGCATTTAGATTATTCCGTATGTGAGATCCGTATCAGCATTTCATTACC TGGGTTTGTTCTAAAGAAGATTTATTTTTGTTCTGTGAATAATTTTTGACAGTTCTTGTACATGTACAGATATAGATACGTTTGAGGTCT TTTATTGATATTCCTACAAAGAATACAAATAAACTTTAACTTTAAACATTTCAGACTAAAGTTGCTACTATATTTGACATATTGCTGTCT TCTAGCATGCACCTGGGTGACTAGGACACTTGAAGAGAAACAAGAAAGGAAATGTATGCCGGAATATTCTTCTAAAAATATATTTTAACA TTAAGAACAGTCTGTCCTAGAATTTCCCAACTTCCATGTAATAAGATTTCAATTTAGGAAAAATAACTAGCATTAGCATGTATTGTGATA AAACTGTTACTTTCGAATTCTGCAGAATTTGAAATCTCTTTAATAACTTGTGACAGGTAAAGAAAGTTTCATCTGGTTTATTAGGAAATG TAGCCCCACTTAGCTTCCTAGACCACTACCATCCTCTTGTAATTTTCCAGTTAGATTAATGGGGTTTGTTTTCAGGATTTTTGATGTTTG GTTCAGGTTTTTTATTTTAATTTCTTAATAGAAGTTCATTTGTCATTCCCAACATGATTGTTCCCAAATACACCCATCTTCTCCTGCATC CCTGTTTCATTCTGTAAAATCCAGGGATGCAGGTTTCATGTGTAGTCTTGTTTTGTGTTAGTTGTAGGTCTGTGCTTTTTGGCACATGTC >In-frame_KDM5B_ENST00000367264_chr1_202777230_-_RASAL2_ENST00000367649_chr1_178389646_+_3779nt CAACTCGGACTTGCTGTTGCTCGAGCCGCGTCTGCACGGGTCTCGGACCGAGCGGAGCTCGCAGCCTCGGTCCCGGAGCCCACCTTCGCC TCGCCCTTGCCCAGCCTGCGGTGATGGAGGCGGCCACCACACTGCACCCAGGCCCGCGCCCGGCGCTGCCCCTCGGGGGCCCGGGCCCGC TGGGCGAGTTCCTGCCTCCACCCGAGTGCCCGGTCTTCGAACCCAGCTGGGAAGAGTTCGCGGACCCCTTCGCTTTCATCCACAAGATCC GGCCCATAGCCGAGCAGACTGGCATCTGTAAGGTGCGGCCGCCGCCGGGATTCTTCAGCAAGCGCCTGAAAGGCTCCATCAAGAGGACCA AAAGCCAGTCAAAGCTTGACAGAAACACGAGCTTTCGGCTTCCATCCCTTCGCAGTACAGATGACAGGTCTCGTGGGCTGCCTAAACTAA AAGAGTCACGTTCCCATGAATCCTTGCTGAGCCCATGCAGCACAGTGGAATGTCTGGATCTTGGTAGAGGGGAACCTGTATCAGTGAAAC CACTTCATAGTAGCATCCTTGGACAAGACTTCTGCTTTGAGGTTACCTACTTAAGTGGAAGTAAATGCTTCAGCTGTAATTCTGCTTCTG AGAGAGACAAGTGGATGGAAAACCTTCGCAGGACAGTTCAACCTAATAAGGACAATTGCAGGCGAGCTGAAAATGTTCTTCGTTTATGGA TCATTGAAGCCAAGGACCTTGCCCCTAAAAAGAAATATTTCTGCGAACTGTGCCTTGATGATACCCTCTTTGCTCGTACAACCAGCAAGA CCAAAGCAGACAATATTTTCTGGGGCGAACATTTTGAATTCTTCAGCCTTCCACCTCTTCATAGTATCACAGTTCACATTTACAAGGATG TGGAAAAAAAGAAAAAAAAGGACAAGAATAATTATGTAGGGCTAGTCAACATCCCCACTGCCAGTGTGACTGGTCGCCAATTTGTAGAAA AGTGGTATCCAGTGAGTACACCTACACCCAACAAAGGAAAGACAGGAGGACCTTCTATTCGGATTAAATCACGTTTCCAAACTATCACCA TTCTGCCTATGGAGCAATACAAAGAATTTGCAGAATTTGTCACCAGCAACTACACCATGCTGTGTTCTGTCCTTGAGCCAGTAATTAGTG TGAGAAATAAAGAGGAGTTGGCTTGTGCCTTAGTGCACATTCTTCAAAGTACTGGCAGAGCCAAGGATTTTCTGACTGACTTGGTGATGT CTGAGGTGGATCGTTGTGGAGAGCATGATGTCTTGATCTTCAGAGAGAACACTATTGCCACCAAATCCATTGAGGAATACCTCAAGTTGG TGGGACAACAGTATCTTCATGACGCACTGGGGGAGTTTATCAAAGCTTTGTATGAGTCCGATGAGAACTGTGAAGTGGATCCCAGCAAAT GTTCATCTAGTGAACTGATAGACCATCAGAGCAACCTGAAAATGTGCTGTGAGCTGGCTTTCTGCAAGATCATCAACTCTTACTGTGTTT TCCCTCGTGAGTTGAAAGAAGTGTTTGCATCATGGAAGCAGCAGTGCCTGAACCGTGGCAAGCAAGACATCAGCGAGAGGCTCATCAGTG CCTCATTATTTCTCCGTTTTCTGTGTCCAGCCATTATGTCTCCCAGTCTTTTCAACCTTATGCAGGAGTATCCTGATGACCGCACATCTC GGACTCTAACTCTTATTGCCAAGGTCATTCAGAACCTGGCCAACTTTGCCAAGTTTGGTAACAAAGAGGAATACATGGCATTCATGAATG ATTTTTTAGAACATGAATGGGGTGGAATGAAGCGCTTTCTTTTGGAGATCTCTAATCCAGACACCATCTCAAACACCCCAGGCTTTGATG GTTACATTGATCTGGGCCGAGAGCTTTCAGTTTTGCATTCCTTACTGTGGGAAGTAGTTTCCCAACTTGATAAGGCGACCGTGGCAAAAT TGGGGCCTCTCCCTCGTGTTCTTGCTGATATTACCAAGTCATTGACTAATCCTACGCCAATACAACAGCAACTGAGACGCTTCACTGAAC ATAACTCCAGTCCAAATGTCAGTGGAAGCCTCTCCTCTGGGCTGCAGAAAATATTTGAAGACCCCACTGACAGTGATTTGCATAAACTAA AATCTCCAAGCCAGGACAACACAGACAGCTACTTCAGAGGGAAAACATTATTGCTGGTTCAGCAAGCCTCCTCTCAGAGCATGACTTATT CTGAAAAGGATGAAAGGGAAAGTAGCCTTCCTAATGGTCGGAGCGTCTCCCTCATGGACCTCCAGGACACTCATGCTGCTCAAGTGGAGC ATGCATCTGTCATGCTTGATGTGCCTATACGCTTGACCGGAAGCCAGCTTTCCATAACCCAGGTGGCCAGCATCAAACAGCTGCGGGAAA CCCAGAGCACTCCCCAAAGTGCACCCCAAGTGAGAAGGCCCCTGCACCCAGCCTTGAACCAGCCAGGTGGCCTTCAGCCCTTGTCGTTCC AGAACCCTGTCTATCACCTCAATAACCCAATTCCAGCAATGCCAAAGGCCTCTATAGATTCCAGTTTGGAGAACCTAAGCACTGCCAGTT CCAGAAGCCAAAGTAACAGTGAAGACTTCAAGCTCAGTGGACCCAGCAATAGCAGCATGGAAGATTTCACTAAACGTAGCACTCAGAGTG AGGACTTCTCCAGGCGGCACACGGTGCCAGATAGACACATACCTCTTGCTTTGCCACGACAAAATAGTACTGGGCAGGCCCAGATCCGAA AAGTGGACCAGGGTGGGTTAGGTGCCCGAGCCAAAGCCCCACCATCCCTGCCACACAGTGCTTCTTTACGTAGCACCGGGAGCATGTCAG TGGTGTCCGCAGCCCTGGTGGCCGAACCTGTGCAGAATGGGAGCCGGTCCCGGCAGCAGTCCTCTTCCTCCAGAGAGAGCCCTGTTCCCA AAGTTAGAGCAATCCAGAGACAACAGACACAGCAGGTTCAGTCACCTGTGGACTCTGCCACAATGTCCCCAGTAGAGAGGACAGCAGCCT GGGTTCTGAACAATGGGCAGTATGAAGAGGATGTGGAAGAAACTGAGCAAAATCTAGATGAAGCCAAGCATGCTGAGAAGTATGAACAAG AAATTACTAAACTGAAGGAGCGCCTGAGAGTTTCCAGCCGGCGACTGGAGGAATATGAACGCCGCTTGCTGGTGCAGGAGCAGCAGATGC AGAAGCTGCTGCTGGAATACAAGGCCCGACTGGAGGACAGCGAGGAGCGGCTCCGAAGACAGCAGGAAGAAAAAGATAGCCAGATGAAAA GCATCATCAGCAGGCTAATGGCTGTGGAAGAGGAACTGAAGAAGGATCATGCTGAGATGCAAGCAGTTATTGATGCAAAGCAGAAAATAA TTGATGCACAGGAAAAACGGATCGTGTCCCTGGATTCAGCCAACACCAGACTGATGAGCGCGCTGACCCAAGTGAAGGAGCGGTACAGCA TGCAGGTCCGCAATGGCATCTCCCCCACCAACCCCACCAAGCTTTCCATCACGGAGAATGGTGAATTCAAAAACAGCAGCTGCTGACGGG CTTTGTCTGTGGAAGGAGACAGAAGGAAATTGACCCACTCTCCTATCTCCAGACCTTTACCTAGCCCCTCCAGGTTTACAGAATGTTGCT |
Top |
FusionGenePPI for KDM5B_RASAL2 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| KDM5B | FOXG1, PAX9, PRPF4, CACNA1H, CDC20, PCNX, SMARCC2, DGKQ, CACNA1A, NR4A3, BMP2K, VGLL3, CDX2, CBX4, SLITRK3, AXIN2, FOXC2, ONECUT2, MAF, ELF4, SLC39A6, BRD4, RNF43, RBM15B, PRDM13, GTF2A1, DBNL, CECR6, RHOBTB2, TAF2, SHOX2, ARID1B, HOXA1, GRIN2B, MEOX2, ZNF217, RCOR1, RB1, AR, LMO2, KLF10, HDAC1, CHD3, KDM1A, MTA2, MTA3, HDAC2, RBBP7, RBBP4, MBD2, MBD3, HDAC4, HDAC5, HDAC7, NCOR1, ELAVL1, TFAP2C, MYC, FBXW11, FAM90A1, KRAS, TSPYL6, TRIM25 | RASAL2 | YWHAG, SH3KBP1, UBC, LATS2, YWHAB, CSNK1A1, CSNK1E, CTAGE5, TRAF1, USHBP1, CEP128, TMEM17, SHC1, KCTD3, KIF13B, ZBTB21, KSR1, GIGYF1, CGN, LRFN1, DENND1A, SH3PXD2A, RTKN, SRGAP2, MAST3, EIF4E2, SIPA1L1, PPM1H, LIMA1, MAGI1, DENND4C, TESK2, DCLK1, ZNF638, NF1, HDAC4, CBY1, SRSF12, SYDE1, MAPKAP1, CDC25C, AGAP1, CDC25B, NADK, CDK16, GIGYF2, CAMSAP2, FAM110B, RALGPS2, USP21, KIAA1804, TIAM1, FAM53C, ANKRD34A, PHLDB2, LPIN3, PLEKHA7, KIF1C, INPP5E, TRIM25 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
Top |
RelatedDrugs for KDM5B_RASAL2 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
Top |
RelatedDiseases for KDM5B_RASAL2 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | KDM5B | C0009375 | Colonic Neoplasms | 1 | CTD_human |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
|