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Fusion gene ID: 1843 |
FusionGeneSummary for ANKRD33B_ANKH |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: ANKRD33B_ANKH | Fusion gene ID: 1843 | Hgene | Tgene | Gene symbol | ANKRD33B | ANKH | Gene ID | 651746 | 56172 |
| Gene name | ankyrin repeat domain 33B | ANKH inorganic pyrophosphate transport regulator | |
| Synonyms | - | ANK|CCAL2|CMDJ|CPPDD|HANK|MANK|SLC62A1 | |
| Cytomap | 5p15.2 | 5p15.2 | |
| Type of gene | protein-coding | protein-coding | |
| Description | ankyrin repeat domain-containing protein 33BAnkyrin repeat domain-containing protein LOC651746 | progressive ankylosis protein homologankylosis, progressive homolog | |
| Modification date | 20180519 | 20180519 | |
| UniProtAcc | A6NCL7 | Q9HCJ1 | |
| Ensembl transtripts involved in fusion gene | ENST00000296657, | ENST00000284268, ENST00000535119, ENST00000503939, | |
| Fusion gene scores | * DoF score | 5 X 1 X 4=20 | 9 X 7 X 5=315 |
| # samples | 5 | 9 | |
| ** MAII score | log2(5/20*10)=1.32192809488736 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | log2(9/315*10)=-1.8073549220576 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: ANKRD33B [Title/Abstract] AND ANKH [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | SARC | TCGA-DX-A1KZ-01A | ANKRD33B | chr5 | 10564945 | + | ANKH | chr5 | 14769300 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000296657 | ENST00000284268 | ANKRD33B | chr5 | 10564945 | + | ANKH | chr5 | 14769300 | - |
| 5CDS-intron | ENST00000296657 | ENST00000535119 | ANKRD33B | chr5 | 10564945 | + | ANKH | chr5 | 14769300 | - |
| 5CDS-intron | ENST00000296657 | ENST00000503939 | ANKRD33B | chr5 | 10564945 | + | ANKH | chr5 | 14769300 | - |
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FusionProtFeatures for ANKRD33B_ANKH |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| ANKRD33B | ANKH |
| Regulates intra- and extracellular levels of inorganicpyrophosphate (PPi), probably functioning as PPi transporter. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | ANKRD33B | chr5:10564945 | chr5:14769300 | ENST00000296657 | + | 1 | 4 | 19_25 | 122 | 495 | Compositional bias | Note=Poly-Pro |
| Hgene | ANKRD33B | chr5:10564945 | chr5:14769300 | ENST00000296657 | + | 1 | 4 | 84_113 | 122 | 495 | Repeat | Note=ANK 1 |
| Tgene | >ANKH | chr5:10564945 | chr5:14769300 | ENST00000284268 | - | 0 | 12 | 107_131 | 32 | 493 | Topological domain | Extracellular |
| Tgene | >ANKH | chr5:10564945 | chr5:14769300 | ENST00000284268 | - | 0 | 12 | 153_158 | 32 | 493 | Topological domain | Cytoplasmic |
| Tgene | >ANKH | chr5:10564945 | chr5:14769300 | ENST00000284268 | - | 0 | 12 | 180_189 | 32 | 493 | Topological domain | Extracellular |
| Tgene | >ANKH | chr5:10564945 | chr5:14769300 | ENST00000284268 | - | 0 | 12 | 211_326 | 32 | 493 | Topological domain | Cytoplasmic |
| Tgene | >ANKH | chr5:10564945 | chr5:14769300 | ENST00000284268 | - | 0 | 12 | 348_350 | 32 | 493 | Topological domain | Extracellular |
| Tgene | >ANKH | chr5:10564945 | chr5:14769300 | ENST00000284268 | - | 0 | 12 | 372_403 | 32 | 493 | Topological domain | Cytoplasmic |
| Tgene | >ANKH | chr5:10564945 | chr5:14769300 | ENST00000284268 | - | 0 | 12 | 427_429 | 32 | 493 | Topological domain | Extracellular |
| Tgene | >ANKH | chr5:10564945 | chr5:14769300 | ENST00000284268 | - | 0 | 12 | 453_492 | 32 | 493 | Topological domain | Cytoplasmic |
| Tgene | >ANKH | chr5:10564945 | chr5:14769300 | ENST00000284268 | - | 0 | 12 | 132_152 | 32 | 493 | Transmembrane | Helical |
| Tgene | >ANKH | chr5:10564945 | chr5:14769300 | ENST00000284268 | - | 0 | 12 | 159_179 | 32 | 493 | Transmembrane | Helical |
| Tgene | >ANKH | chr5:10564945 | chr5:14769300 | ENST00000284268 | - | 0 | 12 | 190_210 | 32 | 493 | Transmembrane | Helical |
| Tgene | >ANKH | chr5:10564945 | chr5:14769300 | ENST00000284268 | - | 0 | 12 | 327_347 | 32 | 493 | Transmembrane | Helical |
| Tgene | >ANKH | chr5:10564945 | chr5:14769300 | ENST00000284268 | - | 0 | 12 | 351_371 | 32 | 493 | Transmembrane | Helical |
| Tgene | >ANKH | chr5:10564945 | chr5:14769300 | ENST00000284268 | - | 0 | 12 | 404_426 | 32 | 493 | Transmembrane | Helical |
| Tgene | >ANKH | chr5:10564945 | chr5:14769300 | ENST00000284268 | - | 0 | 12 | 430_452 | 32 | 493 | Transmembrane | Helical |
| Tgene | >ANKH | chr5:10564945 | chr5:14769300 | ENST00000284268 | - | 0 | 12 | 86_106 | 32 | 493 | Transmembrane | Helical |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >ANKRD33B | chr5:10564945 | chr5:14769300 | ENST00000296657 | + | 1 | 4 | 459_488 | 122 | 495 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | >ANKRD33B | chr5:10564945 | chr5:14769300 | ENST00000296657 | + | 1 | 4 | 264_267 | 122 | 495 | Compositional bias | Note=Poly-Pro |
| Hgene | >ANKRD33B | chr5:10564945 | chr5:14769300 | ENST00000296657 | + | 1 | 4 | 120_150 | 122 | 495 | Repeat | Note=ANK 2 |
| Hgene | >ANKRD33B | chr5:10564945 | chr5:14769300 | ENST00000296657 | + | 1 | 4 | 154_183 | 122 | 495 | Repeat | Note=ANK 3 |
| Hgene | >ANKRD33B | chr5:10564945 | chr5:14769300 | ENST00000296657 | + | 1 | 4 | 189_218 | 122 | 495 | Repeat | Note=ANK 4 |
| Hgene | >ANKRD33B | chr5:10564945 | chr5:14769300 | ENST00000296657 | + | 1 | 4 | 223_255 | 122 | 495 | Repeat | Note=ANK 5 |
| Tgene | ANKH | chr5:10564945 | chr5:14769300 | ENST00000284268 | - | 0 | 12 | 1_85 | 32 | 493 | Topological domain | Cytoplasmic |
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FusionGeneSequence for ANKRD33B_ANKH |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_ANKRD33B_ENST00000296657_chr5_10564945_+_ANKH_ENST00000284268_chr5_14769300_-_583aa MVLLAGTGPEGGGARCMTPPPPSPPRGAQVEEDPADYEEFEDFSSLPDTRSIASDDSFYPFEDEEEHGVESAESVPEGVPESVPETATLL RAACANNVGLLRTLVRRGVSVEEAQETDRNGRALNRGIAAVKEDAVEMLASYGLAYSLMKFFTGPMSDFKNVGLVFVNSKRDRTKAVLCM VVAGAIAAVFHTLIAYSDLGYYIINKLHHVDESVGSKTRRAFLYLAAFPFMDAMAWTHAGILLKHKYSFLVGCASISDVIAQVVFVAILL HSHLECREPLLIPILSLYMGALVRCTTLCLGYYKNIHDIIPDRSGPELGGDATIRKMLSFWWPLALILATQRISRPIVNLFVSRDLGGSS AATEAVAILTATYPVGHMPYGWLTEIRAVYPAFDKNNPSNKLVSTSNTVTAAHIKKFTFVCMALSLTLCFVMFWTPNVSEKILIDIIGVD FAFAELCVVPLRIFSFFPVPVTVRAHLTGWLMTLKKTFVLAPSSVLRIIVLIASLVVLPYLGVHGATLGVGSLLAGFVGESTMVAIAACY |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_ANKRD33B_ENST00000296657_chr5_10564945_+_ANKH_ENST00000284268_chr5_14769300_-_1749nt ATGGTGCTGCTGGCCGGGACCGGGCCGGAGGGCGGCGGGGCGCGCTGCATGACCCCACCACCGCCGTCCCCACCCCGGGGCGCGCAGGTC GAGGAGGACCCCGCTGACTACGAAGAGTTTGAGGACTTCTCGAGTCTGCCAGACACCCGCAGCATCGCCTCGGACGACTCTTTCTACCCT TTCGAGGACGAGGAGGAGCACGGCGTCGAGAGCGCGGAGAGCGTCCCGGAGGGCGTCCCGGAAAGCGTCCCGGAGACGGCGACCCTCCTG CGCGCCGCCTGCGCCAACAACGTGGGGCTGCTGCGGACGCTGGTGCGGCGCGGGGTGAGCGTCGAGGAGGCGCAGGAGACTGACCGCAAC GGCAGGGCCTTGAACCGGGGCATTGCTGCTGTCAAGGAGGATGCAGTCGAGATGCTGGCCAGCTACGGGCTGGCGTACTCCCTCATGAAG TTCTTCACGGGTCCCATGAGTGACTTCAAAAATGTGGGCCTGGTGTTTGTGAACAGCAAGAGAGACAGGACCAAAGCCGTCCTGTGTATG GTGGTGGCAGGGGCCATCGCTGCCGTCTTTCACACACTGATAGCTTATAGTGATTTAGGATACTACATTATCAATAAACTGCACCATGTG GACGAGTCGGTGGGGAGCAAGACGAGAAGGGCCTTCCTGTACCTCGCCGCCTTTCCTTTCATGGACGCAATGGCATGGACCCATGCTGGC ATTCTCTTAAAACACAAATACAGTTTCCTGGTGGGATGTGCCTCAATCTCAGATGTCATAGCTCAGGTTGTTTTTGTAGCCATTTTGCTT CACAGTCACCTGGAATGCCGGGAGCCCCTGCTCATCCCGATCCTCTCCTTGTACATGGGCGCACTTGTGCGCTGCACCACCCTGTGCCTG GGCTACTACAAGAACATTCACGACATCATCCCTGACAGAAGTGGCCCGGAGCTGGGGGGAGATGCAACAATAAGAAAGATGCTGAGCTTC TGGTGGCCTTTGGCTCTAATTCTGGCCACACAGAGAATCAGTCGGCCTATTGTCAACCTCTTTGTTTCCCGGGACCTTGGTGGCAGTTCT GCAGCCACAGAGGCAGTGGCGATTTTGACAGCCACATACCCTGTGGGTCACATGCCATACGGCTGGTTGACGGAAATCCGTGCTGTGTAT CCTGCTTTCGACAAGAATAACCCCAGCAACAAACTGGTGAGCACGAGCAACACAGTCACGGCAGCCCACATCAAGAAGTTCACCTTCGTC TGCATGGCTCTGTCACTCACGCTCTGTTTCGTGATGTTTTGGACACCCAACGTGTCTGAGAAAATCTTGATAGACATCATCGGAGTGGAC TTTGCCTTTGCAGAACTCTGTGTTGTTCCTTTGCGGATCTTCTCCTTCTTCCCAGTTCCAGTCACAGTGAGGGCGCATCTCACCGGGTGG CTGATGACACTGAAGAAAACCTTCGTCCTTGCCCCCAGCTCTGTGCTGCGGATCATCGTCCTCATCGCCAGCCTCGTGGTCCTACCCTAC CTGGGGGTGCACGGTGCGACCCTGGGCGTGGGCTCCCTCCTGGCGGGCTTTGTGGGAGAATCCACCATGGTCGCCATCGCTGCGTGCTAT GTCTACCGGAAGCAGAAAAAGAAGATGGAGAATGAGTCGGCCACGGAGGGGGAAGACTCTGCCATGACAGACATGCCTCCGACAGAGGAG |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_ANKRD33B_ENST00000296657_chr5_10564945_+_ANKH_ENST00000284268_chr5_14769300_-_8142nt ATGGTGCTGCTGGCCGGGACCGGGCCGGAGGGCGGCGGGGCGCGCTGCATGACCCCACCACCGCCGTCCCCACCCCGGGGCGCGCAGGTC GAGGAGGACCCCGCTGACTACGAAGAGTTTGAGGACTTCTCGAGTCTGCCAGACACCCGCAGCATCGCCTCGGACGACTCTTTCTACCCT TTCGAGGACGAGGAGGAGCACGGCGTCGAGAGCGCGGAGAGCGTCCCGGAGGGCGTCCCGGAAAGCGTCCCGGAGACGGCGACCCTCCTG CGCGCCGCCTGCGCCAACAACGTGGGGCTGCTGCGGACGCTGGTGCGGCGCGGGGTGAGCGTCGAGGAGGCGCAGGAGACTGACCGCAAC GGCAGGGCCTTGAACCGGGGCATTGCTGCTGTCAAGGAGGATGCAGTCGAGATGCTGGCCAGCTACGGGCTGGCGTACTCCCTCATGAAG TTCTTCACGGGTCCCATGAGTGACTTCAAAAATGTGGGCCTGGTGTTTGTGAACAGCAAGAGAGACAGGACCAAAGCCGTCCTGTGTATG GTGGTGGCAGGGGCCATCGCTGCCGTCTTTCACACACTGATAGCTTATAGTGATTTAGGATACTACATTATCAATAAACTGCACCATGTG GACGAGTCGGTGGGGAGCAAGACGAGAAGGGCCTTCCTGTACCTCGCCGCCTTTCCTTTCATGGACGCAATGGCATGGACCCATGCTGGC ATTCTCTTAAAACACAAATACAGTTTCCTGGTGGGATGTGCCTCAATCTCAGATGTCATAGCTCAGGTTGTTTTTGTAGCCATTTTGCTT CACAGTCACCTGGAATGCCGGGAGCCCCTGCTCATCCCGATCCTCTCCTTGTACATGGGCGCACTTGTGCGCTGCACCACCCTGTGCCTG GGCTACTACAAGAACATTCACGACATCATCCCTGACAGAAGTGGCCCGGAGCTGGGGGGAGATGCAACAATAAGAAAGATGCTGAGCTTC TGGTGGCCTTTGGCTCTAATTCTGGCCACACAGAGAATCAGTCGGCCTATTGTCAACCTCTTTGTTTCCCGGGACCTTGGTGGCAGTTCT GCAGCCACAGAGGCAGTGGCGATTTTGACAGCCACATACCCTGTGGGTCACATGCCATACGGCTGGTTGACGGAAATCCGTGCTGTGTAT CCTGCTTTCGACAAGAATAACCCCAGCAACAAACTGGTGAGCACGAGCAACACAGTCACGGCAGCCCACATCAAGAAGTTCACCTTCGTC TGCATGGCTCTGTCACTCACGCTCTGTTTCGTGATGTTTTGGACACCCAACGTGTCTGAGAAAATCTTGATAGACATCATCGGAGTGGAC TTTGCCTTTGCAGAACTCTGTGTTGTTCCTTTGCGGATCTTCTCCTTCTTCCCAGTTCCAGTCACAGTGAGGGCGCATCTCACCGGGTGG CTGATGACACTGAAGAAAACCTTCGTCCTTGCCCCCAGCTCTGTGCTGCGGATCATCGTCCTCATCGCCAGCCTCGTGGTCCTACCCTAC CTGGGGGTGCACGGTGCGACCCTGGGCGTGGGCTCCCTCCTGGCGGGCTTTGTGGGAGAATCCACCATGGTCGCCATCGCTGCGTGCTAT GTCTACCGGAAGCAGAAAAAGAAGATGGAGAATGAGTCGGCCACGGAGGGGGAAGACTCTGCCATGACAGACATGCCTCCGACAGAGGAG GTGACAGACATCGTGGAAATGAGAGAGGAGAATGAATAAGGCACGGGACGCCATGGGCACTGCAGGGACAGTCAGTCAGGATGACACTTC GGCATCATCTCTTCCCTCTCCCATCGTATTTTGTTCCCTTTTTTTTGTTTTGTTTTGGTAATGAAAGAGGCCTTGATTTAAAGGTTTCGT GTCAATTCTCTAGCATACTGGGTATGCTCACACTGACGGGGGGACCTAGTGAATGGTCTTTACTGTTGCTATGTAAAAACAAACGAAACA ACTGACTTCATACCCCTGCCTCACGAAAACCCAAAAGACACAGCTGCCTCACGGTTGACGTTGTGTCCTCCTCCCCTGGACAATCTCCTC TTGGAACCAAAGGACTGCAGCTGTGCCATCGCGCCTCGGTCACCCTGCACAGCAGGCCACAGACTCTCCTGTCCCCCTTCATCGCTCTTA AGAATCAACAGGTTAAAACTCGGCTTCCTTTGATTTGCTTCCCAGTCACATGGCCGTACAAAGAGATGGAGCCCCGGTGGCCTCTTAAAT TTCCCTTCCGCCACGGAGTTCGAAACCATCTACTCCACACATGCAGGAGGCGGGTGGCACGCTGCAGCCCGGAGTCCCCGTTCACACTGA GGAACGGAGACCTGTGACCACAGCAGGCTGACAGATGGACAGAATCTCCCGTAGAAAGGTTTGGTTTGAAATGCCCCGGGGGCAGCAAAC TGACATGGTTGAATGATAGCATTTCACTCTGCGTTCTCCTAGATCTGAGCAAGCTGTCAGTTCTCACCCCCACCGTGTATATACATGAGC TAACTTTTTTAAATTGTCACAAAAGCGCATCTCCAGATTCCAGACCCTGCCGCATGACTTTTCCTGAAGGCTTGCTTTTCCCTCGCCTTT CCTGAAGGTCGCATTAGAGCGAGTCACATGGAGCATCCTAACTTTGCATTTTAGTTTTTACAGTGAACTGAAGCTTTAAGTCTCATCCAG CATTCTAATGCCAGGTTGCTGTAGGGTAACTTTTGAAGTAGATATATTACCTGGTTCTGCTATCCTTAGTCATAACTCTGCGGTACAGGT AATTGAGAATGTACTACGGTACTTCCCTCCCACACCATACGATAAAGCAAGACATTTTATAACGATACCAGAGTCACTATGTGGTCCTCC CTGAAATAACGCATTCGAAATCCATGCAGTGCAGTATATTTTTCTAAGTTTTGGAAAGCAGGTTTTTTCCTTTAAAAAAATTATAGACAC GGTTCACTAAATTGATTTAGTCAGAATTCCTAGACTGAAAGAACCTAAAAAAAAAAATATTTTAAAGATATAAATATATGCTGTATATGT TATGTAATTTATTTTAGGCTATAATACATTTCCTATTTTCGCATTTTCAATAAAATGTCTCTAATACAATACGGTGATTGCTTGTGTGCT CAACATACCTGCAGTTGAAACGTATTGTATCAATGAACATTGTACCTTATTGGCAGCAGTTTTATAAAGTCCGTCATTTGCATTTGAATG TAAGGCTCAGTAAATGACAGAACTATTTTTCATTATGGGTAACTGGGGAATAAATGGGTCACTGGAGTAGGAATAGAAGTGCAAGCTGGA AAGGCAAAAATGAGAAAGAAAAAGGCAGGCCCTTTGTGTCTACCGTTTTCAGTGCTGTGTGATCATATTGTTCCTCACAGCAAAAAAGAA TGCAAGGGCATAATGTTAGCTGTGAACATGCCAGGGTTGCATTCACATTCCTGGGTACCCAGTGCTGATGGGGTGTGCCCACGTGGGGAC ATGTCCTTGGCGTGCTTCCTCAGAGTGGCTTTTCCTCCATTAATACATATATGAGTACTGAAAAATTAAGTTGCATAGCTGCTTTGCAGT GGTTTCAGAGGCAGATCTGAGAAGATTAAAAAAAAATCTCAATGTATCAGCTTTTTTTAAAGGACATTACTAGAAAATTAAACAGTATTT TTTAACATGTGTGACTTTCATGCTTCTGGGGTTGGAGCTTAAAGATCCAAACTGAGAAAGCAGGCCGGGCATGGTGGCTCATGCCTGTAA TCCCAACACTTTGGGAGGCCAAGGAGGGTGGATCACTTAAGGTCAGGAGTTTGAGACCAGCCTGGCCAACATGGCAAAACCCTGTCTCTA CTAAAAACATAAAAATTAGCTGGGGGTGGTAGCACATACCTGTAATCCCAGCTACTCAGGAGGCTGAGGCAGGAGAATTTGCTTGATCCT GGGAGGCAGAGGTTGTAGTGAGCCGAGATCGCGCCATCGCACTCCAGCCTGGGTGACAAGAGCAAAACTCCATCTCAAAAAAAAAAAAAA TCCTTTCCCTCTAAATCCAGGAAGGATCAGCAAGGGCCTCCTCATTATGAGATGAGGAAATACAACTCCAGAGATTCCTTCAGTGATCAA GATCAGTGGGCCATAATATTTGGTTAGAGTTTCTGAGAACACAGGAAGCAATGCCACACTCAGGCCACCACAATGGAGCTGATTTGGCAG GACTTGTTCAAACCTTTCACCTTAAAGCACGTGATCCTTCTTCGTACATTTTCTTCACTTGGGCTGCTTAAGTCACAGCCTAACAACTTT GAGGCAAAACTGAGAACTGGCATATTCTCCTGCGTTTCTTCTAATCGAGTCCCATCATCCAGCTAGACATGAGAGATCAAACCAGGGAGG GTGACCTTTCTCCTTCCCACTTTTCAGAGTCATTGGGGCAACTTTTTGACTTTTGTGACCAAAGAAACATTCCCCCAAAACATTTATTTT TCATTGTAGGGCATTCAGCTGACAGCTGCATTTTAGAAAGTTACCATGCCTGTGAGATTCTCATGTCAAAGACCAGGGAAAGACCAGGTG TGACTTTCTCCAAAACTGAGTGATTGCTTGTGGATGAATACAATCTAAAAATACAAGGCCATGAAGTAGTTTTTCATTTAGATGCTGAGA AATAATAGGTTTGGGCAGCTCAAAGCATAGGAAATAGTAAGGGTTTTCTAGAGCTCCTCCTTTGGTGGCCTGTTTGAGTAGCACAAGGGA CGTCATCCTAAATGTGCAGTTGCCATTTGTTCTGTAGTGACTTACAGGGATCTCAGTGGCAAAGGGCGTCAGTGAGACAACAACTGAGCA AAAAGAACTAGACGAGGCTTGCGCTTGGAAAGTCACGGTAGGATTGGACCTGCCGGCCACATGGCTCAGGGAGTATTGACGGATTTGCAC ATTGGCAGGAAACTCTCCCGTTTGGGATTCTTTAAATGGGGCACAGAAGGCCACTTGTTTGCATTTCTGGGTAAAAAACAGTCATCCCCC ATGACTGCCTGCATCGGGTTTGTCTTGTGCCAAAGTTACTCTTCCTTTGTTTTTACTTTGCCTTGATTTTTAGCATTAGCTGGTAGTTTG GCTTGGAAATGTCCTGGATAGCCGATTCCCTAAGAAACTGAAACATTTAATATTGGCTTAGGATGTATCAGATGGGGCCAAATAAAGCTT CTTTACAATAGTAAAAGCACTTTATACTTCACTCTCTGAGTCTTCCCAATAAATAACCTTGGGAGGTGCAGGGGGTGGGGGGCCCAGGAT GGGGAGGCCTGGGAGCTCCCAGGGTAGTGACAGAGTTGGGCTGAGTTCTCCAGACGCCAGGATGCGTCGCAGCGGGGCCAGCTCAGGAGT GCTCACTCCCAGCCCTCTGGATCTCTCTCCTGGTTGGAATAATCATTACATATCGTAACTCTCAAAATTTATTCACTTATATTTTCAGAA TAAGAAGTGTGAAATGTTAACAGCTCTCTGCTCTCTTACTTGTTCCCCATTTGGGGATCTTCTGGAGGGAAGGGGCAGGGGGAGAGTAAC TTTTCTATATCCTTGGTTTCTAGGAACACATCGATTTGAAGACTCAGTAGCTGACTGGTTTTTTTTTTTCCCCCTTCAAACTGAAGTGCG AGTGTGCGTGTGTTCCACAAAATAGCAAGTATTTATAGTGTTGTAATTACATTTCCTTGAGAAATATTTTCTTGTATTTAAAAATCTTTC TACTTCAGTAACTCCCAGCAGAACAGTGCCCAGGACAGCATGTGCCGGTTAGTACCAGCTTTGCAGGTGAGCTGACTTCTAAACTTAGGA CGACGTCTTCATCAATCAAACTAGTGCACAGTCCAGAAAAAGGGGTCCTTTATCTTCTAAGTTCTGCTCCTCACCTTTCTTTGGAACCAA AATTGCAGTGGAGTGTGAGGAAGAGCTTTGAAAGACGTGGAGTGTTGAGATGTCTGCATTGCACATTCAGCCGGTTCAAAGCCAGCAGCT CCTGCCTGCATTCTGTAGACATCGCCCTCACACACAGTCCTCTGATGGCTCTCATATAAAGCACTCAAACCGTAGGAAAGCATGTTTTTG AGCAACGTGTCTGGGATACTCCTCTGTGTGGTTATTTTGAATCTCTATTTCTGTCATTGAAGCAGCAAAAAACATCATGTGACTCATCAA CTGATCTAATCACACTTAAAACAGGATGTAGAGAAAAATCTGATGAGAAACGTAAAAGGGCCTGTTGCCTGCCCTTTTAAAGGCAAAATG TCTAAAATCATGCAAATGTTCAAAATGAGAGAAATTGCATTGTGGAATCAAAATAACCCAAACTCCACTCAGAAAAGTCACAAATATATA GTATACTATCTGATCTCAAAAGGGAAAAACGAGATGATAAGACCTTAAGTTTAGACTTTATTTTCTTCTCAAGAGTGGACATTAAATCTA TTAACTTGCAACTTTCTGCTGGGAAGAGCATCAAAGGTGGGCCTCCTAAATCATTTTTGAAAAACCTCTGTCAAGTCCAAGTGGTTCCAG GAGAATTATAGCCAGTATCTTTTAAAATATTTCATTTTAGTGATAATGTTTTTCTCTGCTTCATTTGCAATCAACCAGGATCTCTAAAAG ACTGCATAAGATATATGCACTTTTATAGGTGGCTGTCAGCTACACATAGATTCAGCAAATTTTTTTTATATAGTACCTGTTTTTAAGTTA GGCTACATAACTTAAAGTGCACTTTACTAACAAGACTTGACATTAGCGTCTACAATATGTATATGTAAACAAAAGCACACAAGAACTAGG CACCCTTTCTCTCTCCAAGAGTTTAAGTGGTTTCCTTAGGTTAAAGAAGGGGACAGACCAGCTAAAAATGGTTGTACCACTCACTGTACA ACCTCATGGAAATTCTCACTATAAGATTTAGAGGCAATGTTCCCTAGCTATAAGCCAGGGCAAGAAATGGCGCCTCTGGAGTTGGGGAAC ATTAGGGGAACATTACAACCGGGTAGATGCTGGTTCCCTGAAGTGTGGGGCCATGAACATGCAGGGACCCACGGTTTGAATGAAACAGCT ACTGAAAGCTAAGTTCAAACCACCCTTGCGTAACAAAGGAGTACAGGGTACACATCAACACCAATCACCCAGCACCCCACAGCGATGGTC ATGTCACCGTGCAGCAGGTCCCTTACCCCAGGGCTGCCACATCCACAAGCCTTGCAGTGGCAAATACGCTGCTCCTTGGATTTAATGAGA TATTTTGGTTGCTTAATGATGTACTGATCAGGGAACTGTCTAAAGCTAGTAGGGCCAAGGAGTTAATCAAAGGGCTTCGGGAAAGTGGAC AAGAGCCACACACGTGATTCTGTTCCATGCCGACACTCATTCATTTAAGAAGTGTATTCAAGCTGGAGGCTTCCATATCACTCACGCTTC TTGGCCTCACCTTGCTCATCTGTCCAATGGGAGGCTTGAGCCATTATTGCTAAGGCCCCTTCCTGATCTAACATTCTGTTTATGATCTAG GATTTAGAACGTCGTATGAGATCCTACAATGGAAGAATAAAATCACCTCATTCTTCATTTCAGATCTGAACATTAGCAGTGATCTAGATT TTTTTTTTTTTAAACAAAATTAAGTGTGCTTAGAGTCATTCCTCTACATGGGCTGTGGCTGTCAGCCCATAGGTTTGTCAGTTTCACATC AAAACTGTGGGTATAAACTGTTGAAACCAATCACATTAAAATATTTAGCTGGGCACAGTGGTGTGCATCTGTAGTCCCAGCTACTTGGGA GGCTGAGGCAGGAGGATCGCTTAAGCACAGGAGTTGGAATCCAGCCTGAGCAACAGAGCAAAACCCCGTCTCTAAAATACAAATAAAATA TTTGTGTAGTTTTTGATTAAAATTGACTACAGCGGTCAGTATAAAATACATGTCGCTTTTAAGGAAGTGCTCTTTATGTATCTAACAGAT GGAAGTTTTTGCATTGGTAAGAGCATTTATATATGCTTTGTTTCAGGGTTTATGGATTTGTATTCATATATTGTCAAATAGGTTTCATAC |
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FusionGenePPI for ANKRD33B_ANKH |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| ANKRD33B | NXF1, TRIM25 | ANKH | APOE, RPSA, TRIM25 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for ANKRD33B_ANKH |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for ANKRD33B_ANKH |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Tgene | ANKH | C0856830 | Calcium pyrophosphate arthropathy | 3 | CTD_human;ORPHANET;UNIPROT |
| Tgene | ANKH | C0014175 | Endometriosis | 1 | CTD_human |
| Tgene | ANKH | C0040427 | Tooth Abnormalities | 1 | CTD_human |
| Tgene | ANKH | C0376634 | Craniofacial Abnormalities | 1 | CTD_human |
| Tgene | ANKH | C1852502 | CRANIOMETAPHYSEAL DYSPLASIA, AUTOSOMAL DOMINANT | 1 | CTD_human;UNIPROT |
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