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Fusion gene ID: 18287 |
FusionGeneSummary for KCNK5_RUNX2 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: KCNK5_RUNX2 | Fusion gene ID: 18287 | Hgene | Tgene | Gene symbol | KCNK5 | RUNX2 | Gene ID | 8645 | 860 |
| Gene name | potassium two pore domain channel subfamily K member 5 | runt related transcription factor 2 | |
| Synonyms | K2p5.1|KCNK5b|TASK-2|TASK2 | AML3|CBF-alpha-1|CBFA1|CCD|CCD1|CLCD|OSF-2|OSF2|PEA2aA|PEBP2aA | |
| Cytomap | 6p21.2 | 6p21.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | potassium channel subfamily K member 5K2P5.1 potassium channelTWIK-related acid-sensitive K(+) channel 2TWIK-related acid-sensitive K+ channel 2acid-sensitive potassium channel protein TASK-2potassium channel, subfamily K, member 1 (TASK-2)potassium | runt-related transcription factor 2PEA2-alpha APEBP2-alpha ASL3-3 enhancer factor 1 alpha A subunitSL3/AKV core-binding factor alpha A subunitacute myeloid leukemia 3 proteincore-binding factor, runt domain, alpha subunit 1oncogene AML-3osteoblast | |
| Modification date | 20180523 | 20180523 | |
| UniProtAcc | O95279 | Q13950 | |
| Ensembl transtripts involved in fusion gene | ENST00000359534, | ENST00000541979, ENST00000465038, ENST00000352853, ENST00000371438, ENST00000371436, ENST00000576263, ENST00000371432, ENST00000359524, ENST00000483243, | |
| Fusion gene scores | * DoF score | 3 X 2 X 3=18 | 3 X 3 X 3=27 |
| # samples | 3 | 3 | |
| ** MAII score | log2(3/18*10)=0.736965594166206 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | log2(3/27*10)=0.15200309344505 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
| Context | PubMed: KCNK5 [Title/Abstract] AND RUNX2 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | Oncogene involved fusion gene, in-frame and retained their domain. Tumor suppressor gene involved fusion gene, in-frame but not retained their domain. Tumor suppressor gene involved fusion gene, retained protein feature but frameshift. DDR (DNA damage repair) gene involved fusion gene, in-frame but not retained their domain. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Tgene | RUNX2 | GO:0045892 | negative regulation of transcription, DNA-templated | 11965546 |
| Tgene | RUNX2 | GO:0045893 | positive regulation of transcription, DNA-templated | 11965546 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | KIRP | TCGA-B9-A69E-01A | KCNK5 | chr6 | 39161945 | - | RUNX2 | chr6 | 45479983 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000359534 | ENST00000541979 | KCNK5 | chr6 | 39161945 | - | RUNX2 | chr6 | 45479983 | + |
| In-frame | ENST00000359534 | ENST00000465038 | KCNK5 | chr6 | 39161945 | - | RUNX2 | chr6 | 45479983 | + |
| In-frame | ENST00000359534 | ENST00000352853 | KCNK5 | chr6 | 39161945 | - | RUNX2 | chr6 | 45479983 | + |
| In-frame | ENST00000359534 | ENST00000371438 | KCNK5 | chr6 | 39161945 | - | RUNX2 | chr6 | 45479983 | + |
| In-frame | ENST00000359534 | ENST00000371436 | KCNK5 | chr6 | 39161945 | - | RUNX2 | chr6 | 45479983 | + |
| In-frame | ENST00000359534 | ENST00000576263 | KCNK5 | chr6 | 39161945 | - | RUNX2 | chr6 | 45479983 | + |
| In-frame | ENST00000359534 | ENST00000371432 | KCNK5 | chr6 | 39161945 | - | RUNX2 | chr6 | 45479983 | + |
| In-frame | ENST00000359534 | ENST00000359524 | KCNK5 | chr6 | 39161945 | - | RUNX2 | chr6 | 45479983 | + |
| 5CDS-intron | ENST00000359534 | ENST00000483243 | KCNK5 | chr6 | 39161945 | - | RUNX2 | chr6 | 45479983 | + |
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FusionProtFeatures for KCNK5_RUNX2 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| KCNK5 | RUNX2 |
| pH-dependent, voltage insensitive, outwardly rectifyingpotassium channel. Outward rectification is lost at high externalK(+) concentrations. | Transcription factor involved in osteoblasticdifferentiation and skeletal morphogenesis (PubMed:28505335,PubMed:28738062, PubMed:28703881). Essential for the maturation ofosteoblasts and both intramembranous and endochondralossification. CBF binds to the core site, 5'-PYGPYGGT-3', of anumber of enhancers and promoters, including murine leukemiavirus, polyomavirus enhancer, T-cell receptor enhancers,osteocalcin, osteopontin, bone sialoprotein, alpha 1(I) collagen,LCK, IL-3 and GM-CSF promoters. In osteoblasts, supportstranscription activation: synergizes with SPEN/MINT to enhanceFGFR2-mediated activation of the osteocalcin FGF-responsiveelement (OCFRE) (By similarity). Inhibits KAT6B-dependenttranscriptional activation. {ECO:0000250,ECO:0000269|PubMed:11965546, ECO:0000269|PubMed:28505335,ECO:0000269|PubMed:28703881, ECO:0000269|PubMed:28738062}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | KCNK5 | chr6:39161945 | chr6:45479983 | ENST00000359534 | - | 4 | 5 | 85_112 | 211 | 500 | Intramembrane | Pore-forming%3B Name%3DPore-forming 1 |
| Hgene | KCNK5 | chr6:39161945 | chr6:45479983 | ENST00000359534 | - | 4 | 5 | 134_157 | 211 | 500 | Topological domain | Cytoplasmic |
| Hgene | KCNK5 | chr6:39161945 | chr6:45479983 | ENST00000359534 | - | 4 | 5 | 1_7 | 211 | 500 | Topological domain | Cytoplasmic |
| Hgene | KCNK5 | chr6:39161945 | chr6:45479983 | ENST00000359534 | - | 4 | 5 | 113_133 | 211 | 500 | Transmembrane | Helical |
| Hgene | KCNK5 | chr6:39161945 | chr6:45479983 | ENST00000359534 | - | 4 | 5 | 158_180 | 211 | 500 | Transmembrane | Helical |
| Hgene | KCNK5 | chr6:39161945 | chr6:45479983 | ENST00000359534 | - | 4 | 5 | 8_26 | 211 | 500 | Transmembrane | Helical |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >KCNK5 | chr6:39161945 | chr6:45479983 | ENST00000359534 | - | 4 | 5 | 190_215 | 211 | 500 | Intramembrane | Pore-forming%3B Name%3DPore-forming 2 |
| Hgene | >KCNK5 | chr6:39161945 | chr6:45479983 | ENST00000359534 | - | 4 | 5 | 251_325 | 211 | 500 | Topological domain | Cytoplasmic |
| Hgene | >KCNK5 | chr6:39161945 | chr6:45479983 | ENST00000359534 | - | 4 | 5 | 230_250 | 211 | 500 | Transmembrane | Helical |
| Tgene | RUNX2 | chr6:39161945 | chr6:45479983 | ENST00000359524 | + | 3 | 7 | 237_521 | 272 | 508 | Compositional bias | Note=Pro/Ser/Thr-rich |
| Tgene | RUNX2 | chr6:39161945 | chr6:45479983 | ENST00000359524 | + | 3 | 7 | 49_71 | 272 | 508 | Compositional bias | Note=Poly-Gln |
| Tgene | RUNX2 | chr6:39161945 | chr6:45479983 | ENST00000359524 | + | 3 | 7 | 73_89 | 272 | 508 | Compositional bias | Note=Poly-Ala |
| Tgene | RUNX2 | chr6:39161945 | chr6:45479983 | ENST00000371436 | + | 4 | 7 | 237_521 | 286 | 500 | Compositional bias | Note=Pro/Ser/Thr-rich |
| Tgene | RUNX2 | chr6:39161945 | chr6:45479983 | ENST00000371436 | + | 4 | 7 | 49_71 | 286 | 500 | Compositional bias | Note=Poly-Gln |
| Tgene | RUNX2 | chr6:39161945 | chr6:45479983 | ENST00000371436 | + | 4 | 7 | 73_89 | 286 | 500 | Compositional bias | Note=Poly-Ala |
| Tgene | RUNX2 | chr6:39161945 | chr6:45479983 | ENST00000371438 | + | 4 | 8 | 237_521 | 286 | 522 | Compositional bias | Note=Pro/Ser/Thr-rich |
| Tgene | RUNX2 | chr6:39161945 | chr6:45479983 | ENST00000371438 | + | 4 | 8 | 49_71 | 286 | 522 | Compositional bias | Note=Poly-Gln |
| Tgene | RUNX2 | chr6:39161945 | chr6:45479983 | ENST00000371438 | + | 4 | 8 | 73_89 | 286 | 522 | Compositional bias | Note=Poly-Ala |
| Tgene | RUNX2 | chr6:39161945 | chr6:45479983 | ENST00000465038 | + | 5 | 9 | 237_521 | 286 | 522 | Compositional bias | Note=Pro/Ser/Thr-rich |
| Tgene | RUNX2 | chr6:39161945 | chr6:45479983 | ENST00000465038 | + | 5 | 9 | 49_71 | 286 | 522 | Compositional bias | Note=Poly-Gln |
| Tgene | RUNX2 | chr6:39161945 | chr6:45479983 | ENST00000465038 | + | 5 | 9 | 73_89 | 286 | 522 | Compositional bias | Note=Poly-Ala |
| Tgene | RUNX2 | chr6:39161945 | chr6:45479983 | ENST00000359524 | + | 3 | 7 | 101_229 | 272 | 508 | Domain | Runt |
| Tgene | RUNX2 | chr6:39161945 | chr6:45479983 | ENST00000371436 | + | 4 | 7 | 101_229 | 286 | 500 | Domain | Runt |
| Tgene | RUNX2 | chr6:39161945 | chr6:45479983 | ENST00000371438 | + | 4 | 8 | 101_229 | 286 | 522 | Domain | Runt |
| Tgene | RUNX2 | chr6:39161945 | chr6:45479983 | ENST00000465038 | + | 5 | 9 | 101_229 | 286 | 522 | Domain | Runt |
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FusionGeneSequence for KCNK5_RUNX2 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_KCNK5_ENST00000359534_chr6_39161945_-_RUNX2_ENST00000541979_chr6_45479983_+_425aa MVDRGPLLTSAIIFYLAIGAAIFEVLEEPHWKEAKKNYYTQKLHLLKEFPCLGQEGLDKILEVVSDAAGQGVAITGNQTFNNWNWPNAMI FAATVITTIGTGNVAPKTPAGRLFCVFTGLFGVPLCLTWISALGKFFGGRAKRLGQFLTKRGVSLRKAQITCTVIFIVWGVLVHLVIPPF VFMVTEGWNYIEGLYYSFITISTIGFGDFVADPRQAQSSPPWSTDQSYPSYLSQMTSPSIHSTTPLSSTRGTGLPAITDVPRRISGASEL GPFSDPRQFPSISSLTESRFSNPRMHTPATFTYTPPVTSGMSLGMSATTHYHTYLPPPYPGSSQSQSGPFQTSSTPTLYTGTSSGSTQFP >In-frame_KCNK5_ENST00000359534_chr6_39161945_-_RUNX2_ENST00000465038_chr6_45479983_+_447aa MVDRGPLLTSAIIFYLAIGAAIFEVLEEPHWKEAKKNYYTQKLHLLKEFPCLGQEGLDKILEVVSDAAGQGVAITGNQTFNNWNWPNAMI FAATVITTIGTGNVAPKTPAGRLFCVFTGLFGVPLCLTWISALGKFFGGRAKRLGQFLTKRGVSLRKAQITCTVIFIVWGVLVHLVIPPF VFMVTEGWNYIEGLYYSFITISTIGFGDFVADPRQAQSSPPWSTDQSYPSYLSQMTSPSIHSTTPLSSTRGTGLPAITDVPRRISDDDTA TSDFCLWPSTLSKKSQAGASELGPFSDPRQFPSISSLTESRFSNPRMHTPATFTYTPPVTSGMSLGMSATTHYHTYLPPPYPGSSQSQSG >In-frame_KCNK5_ENST00000359534_chr6_39161945_-_RUNX2_ENST00000352853_chr6_45479983_+_447aa MVDRGPLLTSAIIFYLAIGAAIFEVLEEPHWKEAKKNYYTQKLHLLKEFPCLGQEGLDKILEVVSDAAGQGVAITGNQTFNNWNWPNAMI FAATVITTIGTGNVAPKTPAGRLFCVFTGLFGVPLCLTWISALGKFFGGRAKRLGQFLTKRGVSLRKAQITCTVIFIVWGVLVHLVIPPF VFMVTEGWNYIEGLYYSFITISTIGFGDFVADPRQAQSSPPWSTDQSYPSYLSQMTSPSIHSTTPLSSTRGTGLPAITDVPRRISDDDTA TSDFCLWPSTLSKKSQAGASELGPFSDPRQFPSISSLTESRFSNPRMHTPATFTYTPPVTSGMSLGMSATTHYHTYLPPPYPGSSQSQSG >In-frame_KCNK5_ENST00000359534_chr6_39161945_-_RUNX2_ENST00000371438_chr6_45479983_+_447aa MVDRGPLLTSAIIFYLAIGAAIFEVLEEPHWKEAKKNYYTQKLHLLKEFPCLGQEGLDKILEVVSDAAGQGVAITGNQTFNNWNWPNAMI FAATVITTIGTGNVAPKTPAGRLFCVFTGLFGVPLCLTWISALGKFFGGRAKRLGQFLTKRGVSLRKAQITCTVIFIVWGVLVHLVIPPF VFMVTEGWNYIEGLYYSFITISTIGFGDFVADPRQAQSSPPWSTDQSYPSYLSQMTSPSIHSTTPLSSTRGTGLPAITDVPRRISDDDTA TSDFCLWPSTLSKKSQAGASELGPFSDPRQFPSISSLTESRFSNPRMHTPATFTYTPPVTSGMSLGMSATTHYHTYLPPPYPGSSQSQSG >In-frame_KCNK5_ENST00000359534_chr6_39161945_-_RUNX2_ENST00000371436_chr6_45479983_+_425aa MVDRGPLLTSAIIFYLAIGAAIFEVLEEPHWKEAKKNYYTQKLHLLKEFPCLGQEGLDKILEVVSDAAGQGVAITGNQTFNNWNWPNAMI FAATVITTIGTGNVAPKTPAGRLFCVFTGLFGVPLCLTWISALGKFFGGRAKRLGQFLTKRGVSLRKAQITCTVIFIVWGVLVHLVIPPF VFMVTEGWNYIEGLYYSFITISTIGFGDFVADPRQAQSSPPWSTDQSYPSYLSQMTSPSIHSTTPLSSTRGTGLPAITDVPRRISGASEL GPFSDPRQFPSISSLTESRFSNPRMHTPATFTYTPPVTSGMSLGMSATTHYHTYLPPPYPGSSQSQSGPFQTSSTPTLYTGTSSGSTQFP >In-frame_KCNK5_ENST00000359534_chr6_39161945_-_RUNX2_ENST00000576263_chr6_45479983_+_468aa MVDRGPLLTSAIIFYLAIGAAIFEVLEEPHWKEAKKNYYTQKLHLLKEFPCLGQEGLDKILEVVSDAAGQGVAITGNQTFNNWNWPNAMI FAATVITTIGTGNVAPKTPAGRLFCVFTGLFGVPLCLTWISALGKFFGGRAKRLGQFLTKRGVSLRKAQITCTVIFIVWGVLVHLVIPPF VFMVTEGWNYIEGLYYSFITISTIGFGDFVADPRQAQSSPPWSTDQSYPSYLSQMTSPSIHSTTPLSSTRGTGLPAITDVPRRISDSEPS TLDSQSSTTLFLSSEEPGPSTAALPSPSSSSCEPQAFSPGPPALPPLLPPLPAASAPPGPGASRRTGRYSVVASSPEAAPRLVDWLPGCP STISPSTRGDDKERPPPVLAPAEGPERSRAPRPSTAGREEGTVDAGTSPPPRARPAAAASLEAHVGDILVELRTMNGHLDSIARALTKLA >In-frame_KCNK5_ENST00000359534_chr6_39161945_-_RUNX2_ENST00000371432_chr6_45479983_+_425aa MVDRGPLLTSAIIFYLAIGAAIFEVLEEPHWKEAKKNYYTQKLHLLKEFPCLGQEGLDKILEVVSDAAGQGVAITGNQTFNNWNWPNAMI FAATVITTIGTGNVAPKTPAGRLFCVFTGLFGVPLCLTWISALGKFFGGRAKRLGQFLTKRGVSLRKAQITCTVIFIVWGVLVHLVIPPF VFMVTEGWNYIEGLYYSFITISTIGFGDFVADPRQAQSSPPWSTDQSYPSYLSQMTSPSIHSTTPLSSTRGTGLPAITDVPRRISGASEL GPFSDPRQFPSISSLTESRFSNPRMHTPATFTYTPPVTSGMSLGMSATTHYHTYLPPPYPGSSQSQSGPFQTSSTPTLYTGTSSGSTQFP >In-frame_KCNK5_ENST00000359534_chr6_39161945_-_RUNX2_ENST00000359524_chr6_45479983_+_447aa MVDRGPLLTSAIIFYLAIGAAIFEVLEEPHWKEAKKNYYTQKLHLLKEFPCLGQEGLDKILEVVSDAAGQGVAITGNQTFNNWNWPNAMI FAATVITTIGTGNVAPKTPAGRLFCVFTGLFGVPLCLTWISALGKFFGGRAKRLGQFLTKRGVSLRKAQITCTVIFIVWGVLVHLVIPPF VFMVTEGWNYIEGLYYSFITISTIGFGDFVADPRQAQSSPPWSTDQSYPSYLSQMTSPSIHSTTPLSSTRGTGLPAITDVPRRISDDDTA TSDFCLWPSTLSKKSQAGASELGPFSDPRQFPSISSLTESRFSNPRMHTPATFTYTPPVTSGMSLGMSATTHYHTYLPPPYPGSSQSQSG |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_KCNK5_ENST00000359534_chr6_39161945_-_RUNX2_ENST00000541979_chr6_45479983_+_1275nt ATGGTGGACCGGGGCCCTCTGCTCACCTCGGCCATCATCTTCTACCTGGCCATCGGGGCGGCGATCTTCGAAGTGCTGGAGGAGCCACAC TGGAAGGAGGCCAAGAAAAACTACTACACACAGAAGCTGCATCTGCTCAAGGAGTTCCCGTGCCTGGGTCAGGAGGGCCTGGACAAGATC CTAGAGGTGGTATCTGATGCTGCAGGACAGGGTGTGGCCATCACAGGGAACCAGACCTTCAACAACTGGAACTGGCCCAATGCAATGATT TTTGCAGCGACCGTCATTACCACCATTGGATATGGCAATGTGGCTCCCAAGACCCCCGCCGGTCGCCTCTTCTGTGTTTTCTATGGTCTC TTCGGGGTGCCGCTCTGCCTGACGTGGATCAGTGCCCTGGGCAAGTTCTTCGGGGGACGTGCCAAGAGACTAGGGCAGTTCCTTACCAAG AGAGGTGTGAGTCTGCGGAAGGCGCAGATCACGTGCACAGTCATCTTCATCGTGTGGGGCGTCCTAGTCCACCTGGTGATCCCACCCTTC GTATTCATGGTGACTGAGGGGTGGAACTACATCGAGGGCCTCTACTACTCCTTCATCACCATCTCCACCATCGGCTTCGGTGACTTTGTG GCCGACCCCAGGCAGGCACAGTCTTCCCCGCCGTGGTCCTATGACCAGTCTTACCCCTCCTACCTGAGCCAGATGACGTCCCCGTCCATC CACTCTACCACCCCGCTGTCTTCCACACGGGGCACTGGGCTTCCTGCCATCACCGATGTGCCTAGGCGCATTTCAGGTGCTTCAGAACTG GGCCCTTTTTCAGACCCCAGGCAGTTCCCAAGCATTTCATCCCTCACTGAGAGCCGCTTCTCCAACCCACGAATGCACTATCCAGCCACC TTTACTTACACCCCGCCAGTCACCTCAGGCATGTCCCTCGGTATGTCCGCCACCACTCACTACCACACCTACCTGCCACCACCCTACCCC GGCTCTTCCCAAAGCCAGAGTGGACCCTTCCAGACCAGCAGCACTCCATATCTCTACTATGGCACTTCGTCAGGATCCTATCAGTTTCCC ATGGTGCCGGGGGGAGACCGGTCTCCTTCCAGAATGCTTCCGCCATGCACCACCACCTCGAATGGCAGCACGCTATTAAATCCAAATTTG CCTAACCAGAATGATGGTGTTGACGCTGATGGAAGCCACAGCAGTTCCCCAACTGTTTTGAATTCTAGTGGCAGAATGGATGAATCTGTT >In-frame_KCNK5_ENST00000359534_chr6_39161945_-_RUNX2_ENST00000465038_chr6_45479983_+_1341nt ATGGTGGACCGGGGCCCTCTGCTCACCTCGGCCATCATCTTCTACCTGGCCATCGGGGCGGCGATCTTCGAAGTGCTGGAGGAGCCACAC TGGAAGGAGGCCAAGAAAAACTACTACACACAGAAGCTGCATCTGCTCAAGGAGTTCCCGTGCCTGGGTCAGGAGGGCCTGGACAAGATC CTAGAGGTGGTATCTGATGCTGCAGGACAGGGTGTGGCCATCACAGGGAACCAGACCTTCAACAACTGGAACTGGCCCAATGCAATGATT TTTGCAGCGACCGTCATTACCACCATTGGATATGGCAATGTGGCTCCCAAGACCCCCGCCGGTCGCCTCTTCTGTGTTTTCTATGGTCTC TTCGGGGTGCCGCTCTGCCTGACGTGGATCAGTGCCCTGGGCAAGTTCTTCGGGGGACGTGCCAAGAGACTAGGGCAGTTCCTTACCAAG AGAGGTGTGAGTCTGCGGAAGGCGCAGATCACGTGCACAGTCATCTTCATCGTGTGGGGCGTCCTAGTCCACCTGGTGATCCCACCCTTC GTATTCATGGTGACTGAGGGGTGGAACTACATCGAGGGCCTCTACTACTCCTTCATCACCATCTCCACCATCGGCTTCGGTGACTTTGTG GCCGACCCCAGGCAGGCACAGTCTTCCCCGCCGTGGTCCTATGACCAGTCTTACCCCTCCTACCTGAGCCAGATGACGTCCCCGTCCATC CACTCTACCACCCCGCTGTCTTCCACACGGGGCACTGGGCTTCCTGCCATCACCGATGTGCCTAGGCGCATTTCAGATGATGACACTGCC ACCTCTGACTTCTGCCTCTGGCCTTCCACTCTCAGTAAGAAGAGCCAGGCAGGTGCTTCAGAACTGGGCCCTTTTTCAGACCCCAGGCAG TTCCCAAGCATTTCATCCCTCACTGAGAGCCGCTTCTCCAACCCACGAATGCACTATCCAGCCACCTTTACTTACACCCCGCCAGTCACC TCAGGCATGTCCCTCGGTATGTCCGCCACCACTCACTACCACACCTACCTGCCACCACCCTACCCCGGCTCTTCCCAAAGCCAGAGTGGA CCCTTCCAGACCAGCAGCACTCCATATCTCTACTATGGCACTTCGTCAGGATCCTATCAGTTTCCCATGGTGCCGGGGGGAGACCGGTCT CCTTCCAGAATGCTTCCGCCATGCACCACCACCTCGAATGGCAGCACGCTATTAAATCCAAATTTGCCTAACCAGAATGATGGTGTTGAC >In-frame_KCNK5_ENST00000359534_chr6_39161945_-_RUNX2_ENST00000352853_chr6_45479983_+_1341nt ATGGTGGACCGGGGCCCTCTGCTCACCTCGGCCATCATCTTCTACCTGGCCATCGGGGCGGCGATCTTCGAAGTGCTGGAGGAGCCACAC TGGAAGGAGGCCAAGAAAAACTACTACACACAGAAGCTGCATCTGCTCAAGGAGTTCCCGTGCCTGGGTCAGGAGGGCCTGGACAAGATC CTAGAGGTGGTATCTGATGCTGCAGGACAGGGTGTGGCCATCACAGGGAACCAGACCTTCAACAACTGGAACTGGCCCAATGCAATGATT TTTGCAGCGACCGTCATTACCACCATTGGATATGGCAATGTGGCTCCCAAGACCCCCGCCGGTCGCCTCTTCTGTGTTTTCTATGGTCTC TTCGGGGTGCCGCTCTGCCTGACGTGGATCAGTGCCCTGGGCAAGTTCTTCGGGGGACGTGCCAAGAGACTAGGGCAGTTCCTTACCAAG AGAGGTGTGAGTCTGCGGAAGGCGCAGATCACGTGCACAGTCATCTTCATCGTGTGGGGCGTCCTAGTCCACCTGGTGATCCCACCCTTC GTATTCATGGTGACTGAGGGGTGGAACTACATCGAGGGCCTCTACTACTCCTTCATCACCATCTCCACCATCGGCTTCGGTGACTTTGTG GCCGACCCCAGGCAGGCACAGTCTTCCCCGCCGTGGTCCTATGACCAGTCTTACCCCTCCTACCTGAGCCAGATGACGTCCCCGTCCATC CACTCTACCACCCCGCTGTCTTCCACACGGGGCACTGGGCTTCCTGCCATCACCGATGTGCCTAGGCGCATTTCAGATGATGACACTGCC ACCTCTGACTTCTGCCTCTGGCCTTCCACTCTCAGTAAGAAGAGCCAGGCAGGTGCTTCAGAACTGGGCCCTTTTTCAGACCCCAGGCAG TTCCCAAGCATTTCATCCCTCACTGAGAGCCGCTTCTCCAACCCACGAATGCACTATCCAGCCACCTTTACTTACACCCCGCCAGTCACC TCAGGCATGTCCCTCGGTATGTCCGCCACCACTCACTACCACACCTACCTGCCACCACCCTACCCCGGCTCTTCCCAAAGCCAGAGTGGA CCCTTCCAGACCAGCAGCACTCCATATCTCTACTATGGCACTTCGTCAGGATCCTATCAGTTTCCCATGGTGCCGGGGGGAGACCGGTCT CCTTCCAGAATGCTTCCGCCATGCACCACCACCTCGAATGGCAGCACGCTATTAAATCCAAATTTGCCTAACCAGAATGATGGTGTTGAC >In-frame_KCNK5_ENST00000359534_chr6_39161945_-_RUNX2_ENST00000371438_chr6_45479983_+_1341nt ATGGTGGACCGGGGCCCTCTGCTCACCTCGGCCATCATCTTCTACCTGGCCATCGGGGCGGCGATCTTCGAAGTGCTGGAGGAGCCACAC TGGAAGGAGGCCAAGAAAAACTACTACACACAGAAGCTGCATCTGCTCAAGGAGTTCCCGTGCCTGGGTCAGGAGGGCCTGGACAAGATC CTAGAGGTGGTATCTGATGCTGCAGGACAGGGTGTGGCCATCACAGGGAACCAGACCTTCAACAACTGGAACTGGCCCAATGCAATGATT TTTGCAGCGACCGTCATTACCACCATTGGATATGGCAATGTGGCTCCCAAGACCCCCGCCGGTCGCCTCTTCTGTGTTTTCTATGGTCTC TTCGGGGTGCCGCTCTGCCTGACGTGGATCAGTGCCCTGGGCAAGTTCTTCGGGGGACGTGCCAAGAGACTAGGGCAGTTCCTTACCAAG AGAGGTGTGAGTCTGCGGAAGGCGCAGATCACGTGCACAGTCATCTTCATCGTGTGGGGCGTCCTAGTCCACCTGGTGATCCCACCCTTC GTATTCATGGTGACTGAGGGGTGGAACTACATCGAGGGCCTCTACTACTCCTTCATCACCATCTCCACCATCGGCTTCGGTGACTTTGTG GCCGACCCCAGGCAGGCACAGTCTTCCCCGCCGTGGTCCTATGACCAGTCTTACCCCTCCTACCTGAGCCAGATGACGTCCCCGTCCATC CACTCTACCACCCCGCTGTCTTCCACACGGGGCACTGGGCTTCCTGCCATCACCGATGTGCCTAGGCGCATTTCAGATGATGACACTGCC ACCTCTGACTTCTGCCTCTGGCCTTCCACTCTCAGTAAGAAGAGCCAGGCAGGTGCTTCAGAACTGGGCCCTTTTTCAGACCCCAGGCAG TTCCCAAGCATTTCATCCCTCACTGAGAGCCGCTTCTCCAACCCACGAATGCACTATCCAGCCACCTTTACTTACACCCCGCCAGTCACC TCAGGCATGTCCCTCGGTATGTCCGCCACCACTCACTACCACACCTACCTGCCACCACCCTACCCCGGCTCTTCCCAAAGCCAGAGTGGA CCCTTCCAGACCAGCAGCACTCCATATCTCTACTATGGCACTTCGTCAGGATCCTATCAGTTTCCCATGGTGCCGGGGGGAGACCGGTCT CCTTCCAGAATGCTTCCGCCATGCACCACCACCTCGAATGGCAGCACGCTATTAAATCCAAATTTGCCTAACCAGAATGATGGTGTTGAC >In-frame_KCNK5_ENST00000359534_chr6_39161945_-_RUNX2_ENST00000371436_chr6_45479983_+_1275nt ATGGTGGACCGGGGCCCTCTGCTCACCTCGGCCATCATCTTCTACCTGGCCATCGGGGCGGCGATCTTCGAAGTGCTGGAGGAGCCACAC TGGAAGGAGGCCAAGAAAAACTACTACACACAGAAGCTGCATCTGCTCAAGGAGTTCCCGTGCCTGGGTCAGGAGGGCCTGGACAAGATC CTAGAGGTGGTATCTGATGCTGCAGGACAGGGTGTGGCCATCACAGGGAACCAGACCTTCAACAACTGGAACTGGCCCAATGCAATGATT TTTGCAGCGACCGTCATTACCACCATTGGATATGGCAATGTGGCTCCCAAGACCCCCGCCGGTCGCCTCTTCTGTGTTTTCTATGGTCTC TTCGGGGTGCCGCTCTGCCTGACGTGGATCAGTGCCCTGGGCAAGTTCTTCGGGGGACGTGCCAAGAGACTAGGGCAGTTCCTTACCAAG AGAGGTGTGAGTCTGCGGAAGGCGCAGATCACGTGCACAGTCATCTTCATCGTGTGGGGCGTCCTAGTCCACCTGGTGATCCCACCCTTC GTATTCATGGTGACTGAGGGGTGGAACTACATCGAGGGCCTCTACTACTCCTTCATCACCATCTCCACCATCGGCTTCGGTGACTTTGTG GCCGACCCCAGGCAGGCACAGTCTTCCCCGCCGTGGTCCTATGACCAGTCTTACCCCTCCTACCTGAGCCAGATGACGTCCCCGTCCATC CACTCTACCACCCCGCTGTCTTCCACACGGGGCACTGGGCTTCCTGCCATCACCGATGTGCCTAGGCGCATTTCAGGTGCTTCAGAACTG GGCCCTTTTTCAGACCCCAGGCAGTTCCCAAGCATTTCATCCCTCACTGAGAGCCGCTTCTCCAACCCACGAATGCACTATCCAGCCACC TTTACTTACACCCCGCCAGTCACCTCAGGCATGTCCCTCGGTATGTCCGCCACCACTCACTACCACACCTACCTGCCACCACCCTACCCC GGCTCTTCCCAAAGCCAGAGTGGACCCTTCCAGACCAGCAGCACTCCATATCTCTACTATGGCACTTCGTCAGGATCCTATCAGTTTCCC ATGGTGCCGGGGGGAGACCGGTCTCCTTCCAGAATGCTTCCGCCATGCACCACCACCTCGAATGGCAGCACGCTATTAAATCCAAATTTG CCTAACCAGAATGATGGTGTTGACGCTGATGGAAGCCACAGCAGTTCCCCAACTGTTTTGAATTCTAGTGGCAGAATGGATGAATCTGTT >In-frame_KCNK5_ENST00000359534_chr6_39161945_-_RUNX2_ENST00000576263_chr6_45479983_+_1404nt ATGGTGGACCGGGGCCCTCTGCTCACCTCGGCCATCATCTTCTACCTGGCCATCGGGGCGGCGATCTTCGAAGTGCTGGAGGAGCCACAC TGGAAGGAGGCCAAGAAAAACTACTACACACAGAAGCTGCATCTGCTCAAGGAGTTCCCGTGCCTGGGTCAGGAGGGCCTGGACAAGATC CTAGAGGTGGTATCTGATGCTGCAGGACAGGGTGTGGCCATCACAGGGAACCAGACCTTCAACAACTGGAACTGGCCCAATGCAATGATT TTTGCAGCGACCGTCATTACCACCATTGGATATGGCAATGTGGCTCCCAAGACCCCCGCCGGTCGCCTCTTCTGTGTTTTCTATGGTCTC TTCGGGGTGCCGCTCTGCCTGACGTGGATCAGTGCCCTGGGCAAGTTCTTCGGGGGACGTGCCAAGAGACTAGGGCAGTTCCTTACCAAG AGAGGTGTGAGTCTGCGGAAGGCGCAGATCACGTGCACAGTCATCTTCATCGTGTGGGGCGTCCTAGTCCACCTGGTGATCCCACCCTTC GTATTCATGGTGACTGAGGGGTGGAACTACATCGAGGGCCTCTACTACTCCTTCATCACCATCTCCACCATCGGCTTCGGTGACTTTGTG GCCGACCCCAGGCAGGCACAGTCTTCCCCGCCGTGGTCCTATGACCAGTCTTACCCCTCCTACCTGAGCCAGATGACGTCCCCGTCCATC CACTCTACCACCCCGCTGTCTTCCACACGGGGCACTGGGCTTCCTGCCATCACCGATGTGCCTAGGCGCATTTCAGATTCAGAGCCCAGT ACCTTGGACTCCCAGTCTTCGACCACCTTGTTCCTCTCCTCGGAGGAGCCAGGCCCCTCCACCGCCGCCCTGCCATCTCCCTCCTCCTCT TCCTGCGAGCCTCAGGCCTTTTCCCCAGGTCCGCCAGCGCTGCCTCCGCTGTTGCCTCCGCTCCCCGCAGCCTCGGCGCCCCCAGGCCCC GGCGCCTCCCGGCGCACAGGCCGCTACTCAGTCGTCGCCTCCTCCCCGGAGGCCGCCCCGCGTCTGGTCGACTGGCTCCCCGGTTGCCCT TCGACCATCTCTCCCAGCACACGCGGGGATGACAAGGAGCGGCCGCCGCCCGTCCTGGCACCGGCCGAGGGCCCGGAAAGGAGCCGCGCC CCGCGCCCCAGCACTGCGGGCAGGGAGGAGGGCACCGTGGACGCGGGTACATCCCCGCCGCCCCGAGCCCGGCCCGCCGCTGCGGCGAGC TTGGAGGCCCACGTCGGGGACATCCTGGTGGAGCTGCGGACCATGAACGGCCACCTGGACAGCATAGCGCGGGCCCTCACCAAACTGGCT >In-frame_KCNK5_ENST00000359534_chr6_39161945_-_RUNX2_ENST00000371432_chr6_45479983_+_1275nt ATGGTGGACCGGGGCCCTCTGCTCACCTCGGCCATCATCTTCTACCTGGCCATCGGGGCGGCGATCTTCGAAGTGCTGGAGGAGCCACAC TGGAAGGAGGCCAAGAAAAACTACTACACACAGAAGCTGCATCTGCTCAAGGAGTTCCCGTGCCTGGGTCAGGAGGGCCTGGACAAGATC CTAGAGGTGGTATCTGATGCTGCAGGACAGGGTGTGGCCATCACAGGGAACCAGACCTTCAACAACTGGAACTGGCCCAATGCAATGATT TTTGCAGCGACCGTCATTACCACCATTGGATATGGCAATGTGGCTCCCAAGACCCCCGCCGGTCGCCTCTTCTGTGTTTTCTATGGTCTC TTCGGGGTGCCGCTCTGCCTGACGTGGATCAGTGCCCTGGGCAAGTTCTTCGGGGGACGTGCCAAGAGACTAGGGCAGTTCCTTACCAAG AGAGGTGTGAGTCTGCGGAAGGCGCAGATCACGTGCACAGTCATCTTCATCGTGTGGGGCGTCCTAGTCCACCTGGTGATCCCACCCTTC GTATTCATGGTGACTGAGGGGTGGAACTACATCGAGGGCCTCTACTACTCCTTCATCACCATCTCCACCATCGGCTTCGGTGACTTTGTG GCCGACCCCAGGCAGGCACAGTCTTCCCCGCCGTGGTCCTATGACCAGTCTTACCCCTCCTACCTGAGCCAGATGACGTCCCCGTCCATC CACTCTACCACCCCGCTGTCTTCCACACGGGGCACTGGGCTTCCTGCCATCACCGATGTGCCTAGGCGCATTTCAGGTGCTTCAGAACTG GGCCCTTTTTCAGACCCCAGGCAGTTCCCAAGCATTTCATCCCTCACTGAGAGCCGCTTCTCCAACCCACGAATGCACTATCCAGCCACC TTTACTTACACCCCGCCAGTCACCTCAGGCATGTCCCTCGGTATGTCCGCCACCACTCACTACCACACCTACCTGCCACCACCCTACCCC GGCTCTTCCCAAAGCCAGAGTGGACCCTTCCAGACCAGCAGCACTCCATATCTCTACTATGGCACTTCGTCAGGATCCTATCAGTTTCCC ATGGTGCCGGGGGGAGACCGGTCTCCTTCCAGAATGCTTCCGCCATGCACCACCACCTCGAATGGCAGCACGCTATTAAATCCAAATTTG CCTAACCAGAATGATGGTGTTGACGCTGATGGAAGCCACAGCAGTTCCCCAACTGTTTTGAATTCTAGTGGCAGAATGGATGAATCTGTT >In-frame_KCNK5_ENST00000359534_chr6_39161945_-_RUNX2_ENST00000359524_chr6_45479983_+_1341nt ATGGTGGACCGGGGCCCTCTGCTCACCTCGGCCATCATCTTCTACCTGGCCATCGGGGCGGCGATCTTCGAAGTGCTGGAGGAGCCACAC TGGAAGGAGGCCAAGAAAAACTACTACACACAGAAGCTGCATCTGCTCAAGGAGTTCCCGTGCCTGGGTCAGGAGGGCCTGGACAAGATC CTAGAGGTGGTATCTGATGCTGCAGGACAGGGTGTGGCCATCACAGGGAACCAGACCTTCAACAACTGGAACTGGCCCAATGCAATGATT TTTGCAGCGACCGTCATTACCACCATTGGATATGGCAATGTGGCTCCCAAGACCCCCGCCGGTCGCCTCTTCTGTGTTTTCTATGGTCTC TTCGGGGTGCCGCTCTGCCTGACGTGGATCAGTGCCCTGGGCAAGTTCTTCGGGGGACGTGCCAAGAGACTAGGGCAGTTCCTTACCAAG AGAGGTGTGAGTCTGCGGAAGGCGCAGATCACGTGCACAGTCATCTTCATCGTGTGGGGCGTCCTAGTCCACCTGGTGATCCCACCCTTC GTATTCATGGTGACTGAGGGGTGGAACTACATCGAGGGCCTCTACTACTCCTTCATCACCATCTCCACCATCGGCTTCGGTGACTTTGTG GCCGACCCCAGGCAGGCACAGTCTTCCCCGCCGTGGTCCTATGACCAGTCTTACCCCTCCTACCTGAGCCAGATGACGTCCCCGTCCATC CACTCTACCACCCCGCTGTCTTCCACACGGGGCACTGGGCTTCCTGCCATCACCGATGTGCCTAGGCGCATTTCAGATGATGACACTGCC ACCTCTGACTTCTGCCTCTGGCCTTCCACTCTCAGTAAGAAGAGCCAGGCAGGTGCTTCAGAACTGGGCCCTTTTTCAGACCCCAGGCAG TTCCCAAGCATTTCATCCCTCACTGAGAGCCGCTTCTCCAACCCACGAATGCACTATCCAGCCACCTTTACTTACACCCCGCCAGTCACC TCAGGCATGTCCCTCGGTATGTCCGCCACCACTCACTACCACACCTACCTGCCACCACCCTACCCCGGCTCTTCCCAAAGCCAGAGTGGA CCCTTCCAGACCAGCAGCACTCCATATCTCTACTATGGCACTTCGTCAGGATCCTATCAGTTTCCCATGGTGCCGGGGGGAGACCGGTCT CCTTCCAGAATGCTTCCGCCATGCACCACCACCTCGAATGGCAGCACGCTATTAAATCCAAATTTGCCTAACCAGAATGATGGTGTTGAC |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_KCNK5_ENST00000359534_chr6_39161945_-_RUNX2_ENST00000541979_chr6_45479983_+_1614nt AGCGACGCGTGGAGAAGCGGCCCACGTGTCTGCCCAGAGTCAAGTCCTGTGTTCTTCCCGCTCCTTACGCATCCGCGGTCCAGGGCGCCC TTTCAGCCCCGCTGGTGTTCGCCCACCCCGGGCCGCGTGAGTGGGGCCCCACGCAGCTCCCCGCACTCCGTGGGCCAACTTGGCCAAGCA ACTCTGTCCGGGGAGCGGTGCTTGCGGGGGGTGAGTACCGGGCACTGCGCATGCGGAGCTCCAAATTCAAACAGCTGTTTTCAGAGGCTG GAGGGCGGGCGGACTGGTAGCAGCTGGGGCTAGGAGAGGCTTTCTCTAGGAGGCGGCCGCTCGGGAGCCATGGTGGACCGGGGCCCTCTG CTCACCTCGGCCATCATCTTCTACCTGGCCATCGGGGCGGCGATCTTCGAAGTGCTGGAGGAGCCACACTGGAAGGAGGCCAAGAAAAAC TACTACACACAGAAGCTGCATCTGCTCAAGGAGTTCCCGTGCCTGGGTCAGGAGGGCCTGGACAAGATCCTAGAGGTGGTATCTGATGCT GCAGGACAGGGTGTGGCCATCACAGGGAACCAGACCTTCAACAACTGGAACTGGCCCAATGCAATGATTTTTGCAGCGACCGTCATTACC ACCATTGGATATGGCAATGTGGCTCCCAAGACCCCCGCCGGTCGCCTCTTCTGTGTTTTCTATGGTCTCTTCGGGGTGCCGCTCTGCCTG ACGTGGATCAGTGCCCTGGGCAAGTTCTTCGGGGGACGTGCCAAGAGACTAGGGCAGTTCCTTACCAAGAGAGGTGTGAGTCTGCGGAAG GCGCAGATCACGTGCACAGTCATCTTCATCGTGTGGGGCGTCCTAGTCCACCTGGTGATCCCACCCTTCGTATTCATGGTGACTGAGGGG TGGAACTACATCGAGGGCCTCTACTACTCCTTCATCACCATCTCCACCATCGGCTTCGGTGACTTTGTGGCCGACCCCAGGCAGGCACAG TCTTCCCCGCCGTGGTCCTATGACCAGTCTTACCCCTCCTACCTGAGCCAGATGACGTCCCCGTCCATCCACTCTACCACCCCGCTGTCT TCCACACGGGGCACTGGGCTTCCTGCCATCACCGATGTGCCTAGGCGCATTTCAGGTGCTTCAGAACTGGGCCCTTTTTCAGACCCCAGG CAGTTCCCAAGCATTTCATCCCTCACTGAGAGCCGCTTCTCCAACCCACGAATGCACTATCCAGCCACCTTTACTTACACCCCGCCAGTC ACCTCAGGCATGTCCCTCGGTATGTCCGCCACCACTCACTACCACACCTACCTGCCACCACCCTACCCCGGCTCTTCCCAAAGCCAGAGT GGACCCTTCCAGACCAGCAGCACTCCATATCTCTACTATGGCACTTCGTCAGGATCCTATCAGTTTCCCATGGTGCCGGGGGGAGACCGG TCTCCTTCCAGAATGCTTCCGCCATGCACCACCACCTCGAATGGCAGCACGCTATTAAATCCAAATTTGCCTAACCAGAATGATGGTGTT >In-frame_KCNK5_ENST00000359534_chr6_39161945_-_RUNX2_ENST00000465038_chr6_45479983_+_1680nt AGCGACGCGTGGAGAAGCGGCCCACGTGTCTGCCCAGAGTCAAGTCCTGTGTTCTTCCCGCTCCTTACGCATCCGCGGTCCAGGGCGCCC TTTCAGCCCCGCTGGTGTTCGCCCACCCCGGGCCGCGTGAGTGGGGCCCCACGCAGCTCCCCGCACTCCGTGGGCCAACTTGGCCAAGCA ACTCTGTCCGGGGAGCGGTGCTTGCGGGGGGTGAGTACCGGGCACTGCGCATGCGGAGCTCCAAATTCAAACAGCTGTTTTCAGAGGCTG GAGGGCGGGCGGACTGGTAGCAGCTGGGGCTAGGAGAGGCTTTCTCTAGGAGGCGGCCGCTCGGGAGCCATGGTGGACCGGGGCCCTCTG CTCACCTCGGCCATCATCTTCTACCTGGCCATCGGGGCGGCGATCTTCGAAGTGCTGGAGGAGCCACACTGGAAGGAGGCCAAGAAAAAC TACTACACACAGAAGCTGCATCTGCTCAAGGAGTTCCCGTGCCTGGGTCAGGAGGGCCTGGACAAGATCCTAGAGGTGGTATCTGATGCT GCAGGACAGGGTGTGGCCATCACAGGGAACCAGACCTTCAACAACTGGAACTGGCCCAATGCAATGATTTTTGCAGCGACCGTCATTACC ACCATTGGATATGGCAATGTGGCTCCCAAGACCCCCGCCGGTCGCCTCTTCTGTGTTTTCTATGGTCTCTTCGGGGTGCCGCTCTGCCTG ACGTGGATCAGTGCCCTGGGCAAGTTCTTCGGGGGACGTGCCAAGAGACTAGGGCAGTTCCTTACCAAGAGAGGTGTGAGTCTGCGGAAG GCGCAGATCACGTGCACAGTCATCTTCATCGTGTGGGGCGTCCTAGTCCACCTGGTGATCCCACCCTTCGTATTCATGGTGACTGAGGGG TGGAACTACATCGAGGGCCTCTACTACTCCTTCATCACCATCTCCACCATCGGCTTCGGTGACTTTGTGGCCGACCCCAGGCAGGCACAG TCTTCCCCGCCGTGGTCCTATGACCAGTCTTACCCCTCCTACCTGAGCCAGATGACGTCCCCGTCCATCCACTCTACCACCCCGCTGTCT TCCACACGGGGCACTGGGCTTCCTGCCATCACCGATGTGCCTAGGCGCATTTCAGATGATGACACTGCCACCTCTGACTTCTGCCTCTGG CCTTCCACTCTCAGTAAGAAGAGCCAGGCAGGTGCTTCAGAACTGGGCCCTTTTTCAGACCCCAGGCAGTTCCCAAGCATTTCATCCCTC ACTGAGAGCCGCTTCTCCAACCCACGAATGCACTATCCAGCCACCTTTACTTACACCCCGCCAGTCACCTCAGGCATGTCCCTCGGTATG TCCGCCACCACTCACTACCACACCTACCTGCCACCACCCTACCCCGGCTCTTCCCAAAGCCAGAGTGGACCCTTCCAGACCAGCAGCACT CCATATCTCTACTATGGCACTTCGTCAGGATCCTATCAGTTTCCCATGGTGCCGGGGGGAGACCGGTCTCCTTCCAGAATGCTTCCGCCA TGCACCACCACCTCGAATGGCAGCACGCTATTAAATCCAAATTTGCCTAACCAGAATGATGGTGTTGACGCTGATGGAAGCCACAGCAGT >In-frame_KCNK5_ENST00000359534_chr6_39161945_-_RUNX2_ENST00000352853_chr6_45479983_+_1680nt AGCGACGCGTGGAGAAGCGGCCCACGTGTCTGCCCAGAGTCAAGTCCTGTGTTCTTCCCGCTCCTTACGCATCCGCGGTCCAGGGCGCCC TTTCAGCCCCGCTGGTGTTCGCCCACCCCGGGCCGCGTGAGTGGGGCCCCACGCAGCTCCCCGCACTCCGTGGGCCAACTTGGCCAAGCA ACTCTGTCCGGGGAGCGGTGCTTGCGGGGGGTGAGTACCGGGCACTGCGCATGCGGAGCTCCAAATTCAAACAGCTGTTTTCAGAGGCTG GAGGGCGGGCGGACTGGTAGCAGCTGGGGCTAGGAGAGGCTTTCTCTAGGAGGCGGCCGCTCGGGAGCCATGGTGGACCGGGGCCCTCTG CTCACCTCGGCCATCATCTTCTACCTGGCCATCGGGGCGGCGATCTTCGAAGTGCTGGAGGAGCCACACTGGAAGGAGGCCAAGAAAAAC TACTACACACAGAAGCTGCATCTGCTCAAGGAGTTCCCGTGCCTGGGTCAGGAGGGCCTGGACAAGATCCTAGAGGTGGTATCTGATGCT GCAGGACAGGGTGTGGCCATCACAGGGAACCAGACCTTCAACAACTGGAACTGGCCCAATGCAATGATTTTTGCAGCGACCGTCATTACC ACCATTGGATATGGCAATGTGGCTCCCAAGACCCCCGCCGGTCGCCTCTTCTGTGTTTTCTATGGTCTCTTCGGGGTGCCGCTCTGCCTG ACGTGGATCAGTGCCCTGGGCAAGTTCTTCGGGGGACGTGCCAAGAGACTAGGGCAGTTCCTTACCAAGAGAGGTGTGAGTCTGCGGAAG GCGCAGATCACGTGCACAGTCATCTTCATCGTGTGGGGCGTCCTAGTCCACCTGGTGATCCCACCCTTCGTATTCATGGTGACTGAGGGG TGGAACTACATCGAGGGCCTCTACTACTCCTTCATCACCATCTCCACCATCGGCTTCGGTGACTTTGTGGCCGACCCCAGGCAGGCACAG TCTTCCCCGCCGTGGTCCTATGACCAGTCTTACCCCTCCTACCTGAGCCAGATGACGTCCCCGTCCATCCACTCTACCACCCCGCTGTCT TCCACACGGGGCACTGGGCTTCCTGCCATCACCGATGTGCCTAGGCGCATTTCAGATGATGACACTGCCACCTCTGACTTCTGCCTCTGG CCTTCCACTCTCAGTAAGAAGAGCCAGGCAGGTGCTTCAGAACTGGGCCCTTTTTCAGACCCCAGGCAGTTCCCAAGCATTTCATCCCTC ACTGAGAGCCGCTTCTCCAACCCACGAATGCACTATCCAGCCACCTTTACTTACACCCCGCCAGTCACCTCAGGCATGTCCCTCGGTATG TCCGCCACCACTCACTACCACACCTACCTGCCACCACCCTACCCCGGCTCTTCCCAAAGCCAGAGTGGACCCTTCCAGACCAGCAGCACT CCATATCTCTACTATGGCACTTCGTCAGGATCCTATCAGTTTCCCATGGTGCCGGGGGGAGACCGGTCTCCTTCCAGAATGCTTCCGCCA TGCACCACCACCTCGAATGGCAGCACGCTATTAAATCCAAATTTGCCTAACCAGAATGATGGTGTTGACGCTGATGGAAGCCACAGCAGT >In-frame_KCNK5_ENST00000359534_chr6_39161945_-_RUNX2_ENST00000371438_chr6_45479983_+_5454nt AGCGACGCGTGGAGAAGCGGCCCACGTGTCTGCCCAGAGTCAAGTCCTGTGTTCTTCCCGCTCCTTACGCATCCGCGGTCCAGGGCGCCC TTTCAGCCCCGCTGGTGTTCGCCCACCCCGGGCCGCGTGAGTGGGGCCCCACGCAGCTCCCCGCACTCCGTGGGCCAACTTGGCCAAGCA ACTCTGTCCGGGGAGCGGTGCTTGCGGGGGGTGAGTACCGGGCACTGCGCATGCGGAGCTCCAAATTCAAACAGCTGTTTTCAGAGGCTG GAGGGCGGGCGGACTGGTAGCAGCTGGGGCTAGGAGAGGCTTTCTCTAGGAGGCGGCCGCTCGGGAGCCATGGTGGACCGGGGCCCTCTG CTCACCTCGGCCATCATCTTCTACCTGGCCATCGGGGCGGCGATCTTCGAAGTGCTGGAGGAGCCACACTGGAAGGAGGCCAAGAAAAAC TACTACACACAGAAGCTGCATCTGCTCAAGGAGTTCCCGTGCCTGGGTCAGGAGGGCCTGGACAAGATCCTAGAGGTGGTATCTGATGCT GCAGGACAGGGTGTGGCCATCACAGGGAACCAGACCTTCAACAACTGGAACTGGCCCAATGCAATGATTTTTGCAGCGACCGTCATTACC ACCATTGGATATGGCAATGTGGCTCCCAAGACCCCCGCCGGTCGCCTCTTCTGTGTTTTCTATGGTCTCTTCGGGGTGCCGCTCTGCCTG ACGTGGATCAGTGCCCTGGGCAAGTTCTTCGGGGGACGTGCCAAGAGACTAGGGCAGTTCCTTACCAAGAGAGGTGTGAGTCTGCGGAAG GCGCAGATCACGTGCACAGTCATCTTCATCGTGTGGGGCGTCCTAGTCCACCTGGTGATCCCACCCTTCGTATTCATGGTGACTGAGGGG TGGAACTACATCGAGGGCCTCTACTACTCCTTCATCACCATCTCCACCATCGGCTTCGGTGACTTTGTGGCCGACCCCAGGCAGGCACAG TCTTCCCCGCCGTGGTCCTATGACCAGTCTTACCCCTCCTACCTGAGCCAGATGACGTCCCCGTCCATCCACTCTACCACCCCGCTGTCT TCCACACGGGGCACTGGGCTTCCTGCCATCACCGATGTGCCTAGGCGCATTTCAGATGATGACACTGCCACCTCTGACTTCTGCCTCTGG CCTTCCACTCTCAGTAAGAAGAGCCAGGCAGGTGCTTCAGAACTGGGCCCTTTTTCAGACCCCAGGCAGTTCCCAAGCATTTCATCCCTC ACTGAGAGCCGCTTCTCCAACCCACGAATGCACTATCCAGCCACCTTTACTTACACCCCGCCAGTCACCTCAGGCATGTCCCTCGGTATG TCCGCCACCACTCACTACCACACCTACCTGCCACCACCCTACCCCGGCTCTTCCCAAAGCCAGAGTGGACCCTTCCAGACCAGCAGCACT CCATATCTCTACTATGGCACTTCGTCAGGATCCTATCAGTTTCCCATGGTGCCGGGGGGAGACCGGTCTCCTTCCAGAATGCTTCCGCCA TGCACCACCACCTCGAATGGCAGCACGCTATTAAATCCAAATTTGCCTAACCAGAATGATGGTGTTGACGCTGATGGAAGCCACAGCAGT TCCCCAACTGTTTTGAATTCTAGTGGCAGAATGGATGAATCTGTTTGGCGACCATATTGAAATTCCTCAGCAGTGGCCCAGTGGTATCTG GGGGCCACATCCCACACGTATCAATATATACATATATAGAGAGAGTGCATATATATGTATATCGATTAGCTATCTACAAAGTGCCTATTT TTTAGAAGATTTTTCATTCACTCACTCAGTCATGATCTTGCAGCCATAAGAGGGTAGATATTGAGAAGCAGAAGGCTCAAGAGAGACAAT TGCAATCGAGCTTCAGATTGTTTACTATTTAAGATGTACTTTTACAAAGGAACAAAGAAGGGAAAAGGTATTTTTGTTTTTGTTGTTTGG TCTGTTATCATCAATAACCTGTTCATATGCCAATTCAGAGAGGTGGACTCCAGGTTCAGGAGGGAGAAGAGCAAAGCCGCTTCCTCTCTG TGCTTTGAAACTTCACACCCTCACGGTGGCAGCTGTGTATGGACCAGTGCCCTCCGCAGACAGCTCACAAAACCAGTTGAGGTGCACTAA AGGGACATGAGGTAGAATGGATGCTTCCATCACAGTACCATCATTCAGAATAACTCTTCCAATTTCTGCTTTCAGACATGCTGCAGGTCC TCATCTGAACTGTTGGGTTCGTTTTTTTTTTTTTTTTTCCTGCTCCAAGAAAGTGACTTCAAAAATAACTGATCAGGATAGATTATTTTA TTTTACTTTTTAACACTCCTTCTCCCCTTTTCCCACTGAACCAAAAAGAAATCCCATCCCTAAAACCTGCCTTCTCCTTTTATGCAAAAC TGAAAATGGCAATACATTATTATAGCCATAATGGTATAGATAGTGATTGCGTTTGGCTATGTGTTGTTTTCTTTTTTTTTAAATTATGAA TATGTGTAAAATCTGAGGTAACTTGCTAACGTGAATGGTCATATAACTTTAAAGATATATTTATAATTATTTAATGACATTTGGACCCTT GAAACATTTCTTAGTGTATTGATATGTTGACTTCGGTCTCTAAAAGTGCTCTTTATTAAATAACAAATTTCTTCAGTGGTCTAGAGCCAT ATCTGAAATATTGCTAAGCAATTTCAGTTCATCCAGGCACAATGTGATTTTAAAAAATACTTCCATCTCCAAATATTTTAGATATAGATT GTTTTTGTGATGTATGAAGGAAATGTTATGTTTAGTTCTTTCAGATCTTTGAATGCCTCTAACACAGCTTTGCCTTCTAAAGCGGTAATT AGGGATTTAAAAAACAACCTTTAGCCCTTTATCAGCATGAAATGCTGGAGTGATGTGGTTTTCTAATTTCTTTGGGGTAATTATGACTCT TGTCATATTAAAAAGACAAGCACAAGTAAATCATTGAACTACAGAAAAATGTTCTGTGGTTTCATAGTTAAGCAAAACTCTAAATCGCCA GGCTTCATAGCAAAGACATAGTCAGCTAAAAGCCGCACATGTGGATAGAGGGTTCAATTATGAGACACCTAGTACAGGAGAGCAAAATTG CACCAGAGATTCTTAACCAACCAGCCTTACCAAACAACACAACAGGGGAACCCCAATCTGCCTTACCCAAGGCCCCACTGGCAGCTTTCC ACAGAATTTGCATTTAGAGGAGCAGAATGACATCACTGTCCTTTGGGAGTAGGTCCTCTGAAAAGGCAGCAGGTTCCAGCAGGTAGCTGA GCTGAGAGGACATATGGCCCACGGGGACCTACAGACAGCCTTTGACATTTGTATTTCTTACAATGGAGGGCCAAGGAGGGCAAGGGGCTG TGGAGTTTGGTGTCTACTAGTGTGTATGAATTTGAGCTAGAGTCCTTCTGTGGCATGCACTTTGACCACTCCTGGCAGTCACATGGCAGA TTTCCAAGTGCAAATCCTTAATCCAAACAAGGATCATCTAATGACACCACCAGGCCAATCCCTGCTCTCCTCCCCGAAAAGTCAGGGTCC CTTCATTGGAATCCTCCACCCACCCAAGCAGAATTTAGCAGAGATTTGCCTTCAAACCCTAACGGCCCCCTTGTTCTCTGGTCCTTCTCA AACCCACCTTTGTAGGCCACCCAGCATTGCAGGACAGCGTGTGGGGCAGCTGGACCTGTGCTTCCTGCCTGGGAGTCTCCCTTGGAATTC ATCCTGACTCCTTCTAATAAAAATGGATGGGAAAGCAAAACACTTTGCCTTCTAAAGGCCGTATACCAAGTATGCTTAGATAAATAAGCC ACTTTTCTATTACTTAAGTAAGAAGGAAGTAGTAATTGATACTATTTATTGTTTGTGTGTGGTAGCTTGAAGCACACCACTGTCCATTTA TTTGTAAGTGTAAAATATGTGTGTTTGTTTCAGCAGCACTTAAAAAAGCCAGTGTCTGGTTACACATTTCAATTTTAATTAATTGACATA AAAATGCTACCGCCAGTGCCAGCTGCATCCTATTTAATTAAAAAGGTACTATATTTGTACATTATTTTTTAATGTTAAAAGGGCTTTTTT AAGTTTACAGTACACATACCGAGTGACTTTAGGGATGCTTTTGTGTTGAAATGTTACTATAGTGGCTGCAGGCAGCAACCCAGAAACACT TTAGAAGCTTTTTTTCCTTGGGAAAAATTCAAGCACTTCTTCCCTCCACCCTCACTCCAACCACCCCAATGGGGGTAATTCACATTTCTT AGAACAAATTCTGCCCTTTTTTGGTCTAGGGATTAAAATTTTGTTTTTCTTTCTTTCTTTTTTTTTTTTTTTCACTGAACCCTTAATTTG CACTGGGTCATGTGTTTGATTTGTGATTTCAAGACCAAAGCAAAGTCTTACTACTACTGTGGAACCATGTACTAGTTCCTGGGAATTAAA ATAGCGTGGTTCTCTTTGTAGCACAAACATTGCTGGAATTTGCAGTCTTTTCAATGCAGCCACATTTTTATCCATTTCAGTTGTCTCACA AATTTTAACCCATATCAGAGTTCCAGAACAGGTACCACAGCTTTGGTTTTAGATTAGTGGAATAACATTCAGCCCAGAACTGAGAAACTC AACAGATTAACTATCGTTTGCTCTTTAGACGGTCTCACTGCCTCTCACTTGCCAGAGCCCTTTCAAAATGAGCAGAGAAGTCCACACCAT TAGGGACCATCTGTGATAAATTCAGAAGGGAGGAGATGTGTGTACAGCTTTAAGGATTCCCTCAATTCCGAGGAAAGGGACTGGCCCAGA ATCCAGGTTAATACATGGAAACACGAAGCATTAGCAAAAGTAATAATTATACCTATGGTATTTGAAAGAACAATAATAAAAGACACTTCT TCCAAACCTTGAATTTGTTGTTTTTAGAAAACGAATGCATTTAAAAATATTTTCTATGTGAGAATTTTTTAGATGTGTGTTTACTTCATG TTTACAAATAACTGTTTGCTTTTTAATGCAGTACTTTGAAATATATCAGCCAAAACCATAACTTACAATAATTTCTTAGGTATTCTGAAT AAAATTCCATTTCTTTTGGATATGCTTTACCATTCTTAGGTTTCTGTGGAACAAAAATATTTGTAGCATTTTGTGTAAATACAAGCTTTC ATTTTTATTTTTTCCAATTGCTATTGCCCAAGAATTGCTTTCCATGCACATATTGTAAAAATTCCGCTTTGTGCCACAGGTCATGATTGT GGATGAGTTTACTCTTAACTTCAAAGGGACTATTTGTATTGTATGTTGCAACTGTAAATTGAATTATTTGGCATTTTTCTCATGATTGTA >In-frame_KCNK5_ENST00000359534_chr6_39161945_-_RUNX2_ENST00000371436_chr6_45479983_+_1702nt AGCGACGCGTGGAGAAGCGGCCCACGTGTCTGCCCAGAGTCAAGTCCTGTGTTCTTCCCGCTCCTTACGCATCCGCGGTCCAGGGCGCCC TTTCAGCCCCGCTGGTGTTCGCCCACCCCGGGCCGCGTGAGTGGGGCCCCACGCAGCTCCCCGCACTCCGTGGGCCAACTTGGCCAAGCA ACTCTGTCCGGGGAGCGGTGCTTGCGGGGGGTGAGTACCGGGCACTGCGCATGCGGAGCTCCAAATTCAAACAGCTGTTTTCAGAGGCTG GAGGGCGGGCGGACTGGTAGCAGCTGGGGCTAGGAGAGGCTTTCTCTAGGAGGCGGCCGCTCGGGAGCCATGGTGGACCGGGGCCCTCTG CTCACCTCGGCCATCATCTTCTACCTGGCCATCGGGGCGGCGATCTTCGAAGTGCTGGAGGAGCCACACTGGAAGGAGGCCAAGAAAAAC TACTACACACAGAAGCTGCATCTGCTCAAGGAGTTCCCGTGCCTGGGTCAGGAGGGCCTGGACAAGATCCTAGAGGTGGTATCTGATGCT GCAGGACAGGGTGTGGCCATCACAGGGAACCAGACCTTCAACAACTGGAACTGGCCCAATGCAATGATTTTTGCAGCGACCGTCATTACC ACCATTGGATATGGCAATGTGGCTCCCAAGACCCCCGCCGGTCGCCTCTTCTGTGTTTTCTATGGTCTCTTCGGGGTGCCGCTCTGCCTG ACGTGGATCAGTGCCCTGGGCAAGTTCTTCGGGGGACGTGCCAAGAGACTAGGGCAGTTCCTTACCAAGAGAGGTGTGAGTCTGCGGAAG GCGCAGATCACGTGCACAGTCATCTTCATCGTGTGGGGCGTCCTAGTCCACCTGGTGATCCCACCCTTCGTATTCATGGTGACTGAGGGG TGGAACTACATCGAGGGCCTCTACTACTCCTTCATCACCATCTCCACCATCGGCTTCGGTGACTTTGTGGCCGACCCCAGGCAGGCACAG TCTTCCCCGCCGTGGTCCTATGACCAGTCTTACCCCTCCTACCTGAGCCAGATGACGTCCCCGTCCATCCACTCTACCACCCCGCTGTCT TCCACACGGGGCACTGGGCTTCCTGCCATCACCGATGTGCCTAGGCGCATTTCAGGTGCTTCAGAACTGGGCCCTTTTTCAGACCCCAGG CAGTTCCCAAGCATTTCATCCCTCACTGAGAGCCGCTTCTCCAACCCACGAATGCACTATCCAGCCACCTTTACTTACACCCCGCCAGTC ACCTCAGGCATGTCCCTCGGTATGTCCGCCACCACTCACTACCACACCTACCTGCCACCACCCTACCCCGGCTCTTCCCAAAGCCAGAGT GGACCCTTCCAGACCAGCAGCACTCCATATCTCTACTATGGCACTTCGTCAGGATCCTATCAGTTTCCCATGGTGCCGGGGGGAGACCGG TCTCCTTCCAGAATGCTTCCGCCATGCACCACCACCTCGAATGGCAGCACGCTATTAAATCCAAATTTGCCTAACCAGAATGATGGTGTT GACGCTGATGGAAGCCACAGCAGTTCCCCAACTGTTTTGAATTCTAGTGGCAGAATGGATGAATCTGTTTGGCGACCATATTGAAATTCC >In-frame_KCNK5_ENST00000359534_chr6_39161945_-_RUNX2_ENST00000576263_chr6_45479983_+_2370nt AGCGACGCGTGGAGAAGCGGCCCACGTGTCTGCCCAGAGTCAAGTCCTGTGTTCTTCCCGCTCCTTACGCATCCGCGGTCCAGGGCGCCC TTTCAGCCCCGCTGGTGTTCGCCCACCCCGGGCCGCGTGAGTGGGGCCCCACGCAGCTCCCCGCACTCCGTGGGCCAACTTGGCCAAGCA ACTCTGTCCGGGGAGCGGTGCTTGCGGGGGGTGAGTACCGGGCACTGCGCATGCGGAGCTCCAAATTCAAACAGCTGTTTTCAGAGGCTG GAGGGCGGGCGGACTGGTAGCAGCTGGGGCTAGGAGAGGCTTTCTCTAGGAGGCGGCCGCTCGGGAGCCATGGTGGACCGGGGCCCTCTG CTCACCTCGGCCATCATCTTCTACCTGGCCATCGGGGCGGCGATCTTCGAAGTGCTGGAGGAGCCACACTGGAAGGAGGCCAAGAAAAAC TACTACACACAGAAGCTGCATCTGCTCAAGGAGTTCCCGTGCCTGGGTCAGGAGGGCCTGGACAAGATCCTAGAGGTGGTATCTGATGCT GCAGGACAGGGTGTGGCCATCACAGGGAACCAGACCTTCAACAACTGGAACTGGCCCAATGCAATGATTTTTGCAGCGACCGTCATTACC ACCATTGGATATGGCAATGTGGCTCCCAAGACCCCCGCCGGTCGCCTCTTCTGTGTTTTCTATGGTCTCTTCGGGGTGCCGCTCTGCCTG ACGTGGATCAGTGCCCTGGGCAAGTTCTTCGGGGGACGTGCCAAGAGACTAGGGCAGTTCCTTACCAAGAGAGGTGTGAGTCTGCGGAAG GCGCAGATCACGTGCACAGTCATCTTCATCGTGTGGGGCGTCCTAGTCCACCTGGTGATCCCACCCTTCGTATTCATGGTGACTGAGGGG TGGAACTACATCGAGGGCCTCTACTACTCCTTCATCACCATCTCCACCATCGGCTTCGGTGACTTTGTGGCCGACCCCAGGCAGGCACAG TCTTCCCCGCCGTGGTCCTATGACCAGTCTTACCCCTCCTACCTGAGCCAGATGACGTCCCCGTCCATCCACTCTACCACCCCGCTGTCT TCCACACGGGGCACTGGGCTTCCTGCCATCACCGATGTGCCTAGGCGCATTTCAGATTCAGAGCCCAGTACCTTGGACTCCCAGTCTTCG ACCACCTTGTTCCTCTCCTCGGAGGAGCCAGGCCCCTCCACCGCCGCCCTGCCATCTCCCTCCTCCTCTTCCTGCGAGCCTCAGGCCTTT TCCCCAGGTCCGCCAGCGCTGCCTCCGCTGTTGCCTCCGCTCCCCGCAGCCTCGGCGCCCCCAGGCCCCGGCGCCTCCCGGCGCACAGGC CGCTACTCAGTCGTCGCCTCCTCCCCGGAGGCCGCCCCGCGTCTGGTCGACTGGCTCCCCGGTTGCCCTTCGACCATCTCTCCCAGCACA CGCGGGGATGACAAGGAGCGGCCGCCGCCCGTCCTGGCACCGGCCGAGGGCCCGGAAAGGAGCCGCGCCCCGCGCCCCAGCACTGCGGGC AGGGAGGAGGGCACCGTGGACGCGGGTACATCCCCGCCGCCCCGAGCCCGGCCCGCCGCTGCGGCGAGCTTGGAGGCCCACGTCGGGGAC ATCCTGGTGGAGCTGCGGACCATGAACGGCCACCTGGACAGCATAGCGCGGGCCCTCACCAAACTGGCTTCGTCCCTGGGGCCCCAGCCT GAGCCCCTGCCAGATGTTTCGGATGCCAACTAATGGAGCTCGGCGAGGCTGGGCCGCCCCGGGGCCGAGGGATCGCTTGCACCAGGCATC CCTGCCTGTCCCTCCCCAGCAGCGAAGCGCGCCCAGCGGAGGAGCGGTTGCTCTGCGCAGCTGCCTAGCGGAAAGCACGGCCCTAGCGTT TCAGCGTGAAACAGACCCGGTTGCGCCTCACACCCTCCTCCTCCGCTCTCTCACGGCGGCCCCTGCCCCGGCTTCCTGGCCCTTCACATG CCCTTCTCTTGTCTTGAGCGTCTAGCAGAAAAAGTGCCTGGAAACGGCGGTGGCACCCTGCGAAGGATGCTTAGAGAAACACTCTTTCAC ATCCCATTCCTGCGACTTCCGCGTGGCGTGGAGGGAGAGGAGCTCAAAGCAAGTCGCCAAAGCAGCAGCGAGGCCAGCTCCAGCGTTGGT GGGGCATCCATCTCTGGTGACGTTCACAAGTTTGTTTGTTTTTAAAATCGTTTTTGGAAAAATATTTTTTTTTCCTCATAAGCACATTTC AAGAAGTTTGGAAAATAGAGAAATGAAACAAAATCTGGTGTATTTGTGGAAAAGGGGGGTATTTAAGTCTTTCTTATGAGTAAGAAAGTA >In-frame_KCNK5_ENST00000359534_chr6_39161945_-_RUNX2_ENST00000371432_chr6_45479983_+_5390nt AGCGACGCGTGGAGAAGCGGCCCACGTGTCTGCCCAGAGTCAAGTCCTGTGTTCTTCCCGCTCCTTACGCATCCGCGGTCCAGGGCGCCC TTTCAGCCCCGCTGGTGTTCGCCCACCCCGGGCCGCGTGAGTGGGGCCCCACGCAGCTCCCCGCACTCCGTGGGCCAACTTGGCCAAGCA ACTCTGTCCGGGGAGCGGTGCTTGCGGGGGGTGAGTACCGGGCACTGCGCATGCGGAGCTCCAAATTCAAACAGCTGTTTTCAGAGGCTG GAGGGCGGGCGGACTGGTAGCAGCTGGGGCTAGGAGAGGCTTTCTCTAGGAGGCGGCCGCTCGGGAGCCATGGTGGACCGGGGCCCTCTG CTCACCTCGGCCATCATCTTCTACCTGGCCATCGGGGCGGCGATCTTCGAAGTGCTGGAGGAGCCACACTGGAAGGAGGCCAAGAAAAAC TACTACACACAGAAGCTGCATCTGCTCAAGGAGTTCCCGTGCCTGGGTCAGGAGGGCCTGGACAAGATCCTAGAGGTGGTATCTGATGCT GCAGGACAGGGTGTGGCCATCACAGGGAACCAGACCTTCAACAACTGGAACTGGCCCAATGCAATGATTTTTGCAGCGACCGTCATTACC ACCATTGGATATGGCAATGTGGCTCCCAAGACCCCCGCCGGTCGCCTCTTCTGTGTTTTCTATGGTCTCTTCGGGGTGCCGCTCTGCCTG ACGTGGATCAGTGCCCTGGGCAAGTTCTTCGGGGGACGTGCCAAGAGACTAGGGCAGTTCCTTACCAAGAGAGGTGTGAGTCTGCGGAAG GCGCAGATCACGTGCACAGTCATCTTCATCGTGTGGGGCGTCCTAGTCCACCTGGTGATCCCACCCTTCGTATTCATGGTGACTGAGGGG TGGAACTACATCGAGGGCCTCTACTACTCCTTCATCACCATCTCCACCATCGGCTTCGGTGACTTTGTGGCCGACCCCAGGCAGGCACAG TCTTCCCCGCCGTGGTCCTATGACCAGTCTTACCCCTCCTACCTGAGCCAGATGACGTCCCCGTCCATCCACTCTACCACCCCGCTGTCT TCCACACGGGGCACTGGGCTTCCTGCCATCACCGATGTGCCTAGGCGCATTTCAGGTGCTTCAGAACTGGGCCCTTTTTCAGACCCCAGG CAGTTCCCAAGCATTTCATCCCTCACTGAGAGCCGCTTCTCCAACCCACGAATGCACTATCCAGCCACCTTTACTTACACCCCGCCAGTC ACCTCAGGCATGTCCCTCGGTATGTCCGCCACCACTCACTACCACACCTACCTGCCACCACCCTACCCCGGCTCTTCCCAAAGCCAGAGT GGACCCTTCCAGACCAGCAGCACTCCATATCTCTACTATGGCACTTCGTCAGGATCCTATCAGTTTCCCATGGTGCCGGGGGGAGACCGG TCTCCTTCCAGAATGCTTCCGCCATGCACCACCACCTCGAATGGCAGCACGCTATTAAATCCAAATTTGCCTAACCAGAATGATGGTGTT GACGCTGATGGAAGCCACAGCAGTTCCCCAACTGTTTTGAATTCTAGTGGCAGAATGGATGAATCTGTTTGGCGACCATATTGAAATTCC TCAGCAGTGGCCCAGTGGTATCTGGGGGCCACATCCCACACGTATCAATATATACATATATAGAGAGAGTGCATATATATGTATATCGAT TAGCTATCTACAAAGTGCCTATTTTTTAGAAGATTTTTCATTCACTCACTCAGTCATGATCTTGCAGCCATAAGAGGGTAGATATTGAGA AGCAGAAGGCTCAAGAGAGACAATTGCAATCGAGCTTCAGATTGTTTACTATTTAAGATGTACTTTTACAAAGGAACAAAGAAGGGAAAA GGTATTTTTGTTTTTGTTGTTTGGTCTGTTATCATCAATAACCTGTTCATATGCCAATTCAGAGAGGTGGACTCCAGGTTCAGGAGGGAG AAGAGCAAAGCCGCTTCCTCTCTGTGCTTTGAAACTTCACACCCTCACGGTGGCAGCTGTGTATGGACCAGTGCCCTCCGCAGACAGCTC ACAAAACCAGTTGAGGTGCACTAAAGGGACATGAGGTAGAATGGATGCTTCCATCACAGTACCATCATTCAGAATAACTCTTCCAATTTC TGCTTTCAGACATGCTGCAGGTCCTCATCTGAACTGTTGGGTTCGTTTTTTTTTTTTTTTTTCCTGCTCCAAGAAAGTGACTTCAAAAAT AACTGATCAGGATAGATTATTTTATTTTACTTTTTAACACTCCTTCTCCCCTTTTCCCACTGAACCAAAAAGAAATCCCATCCCTAAAAC CTGCCTTCTCCTTTTATGCAAAACTGAAAATGGCAATACATTATTATAGCCATAATGGTATAGATAGTGATTGCGTTTGGCTATGTGTTG TTTTCTTTTTTTTTAAATTATGAATATGTGTAAAATCTGAGGTAACTTGCTAACGTGAATGGTCATATAACTTTAAAGATATATTTATAA TTATTTAATGACATTTGGACCCTTGAAACATTTCTTAGTGTATTGATATGTTGACTTCGGTCTCTAAAAGTGCTCTTTATTAAATAACAA ATTTCTTCAGTGGTCTAGAGCCATATCTGAAATATTGCTAAGCAATTTCAGTTCATCCAGGCACAATGTGATTTTAAAAAATACTTCCAT CTCCAAATATTTTAGATATAGATTGTTTTTGTGATGTATGAAGGAAATGTTATGTTTAGTTCTTTCAGATCTTTGAATGCCTCTAACACA GCTTTGCCTTCTAAAGCGGTAATTAGGGATTTAAAAAACAACCTTTAGCCCTTTATCAGCATGAAATGCTGGAGTGATGTGGTTTTCTAA TTTCTTTGGGGTAATTATGACTCTTGTCATATTAAAAAGACAAGCACAAGTAAATCATTGAACTACAGAAAAATGTTCTGTGGTTTCATA GTTAAGCAAAACTCTAAATCGCCAGGCTTCATAGCAAAGACATAGTCAGCTAAAAGCCGCACATGTGGATAGAGGGTTCAATTATGAGAC ACCTAGTACAGGAGAGCAAAATTGCACCAGAGATTCTTAACCAACCAGCCTTACCAAACAACACAACAGGGGAACCCCAATCTGCCTTAC CCAAGGCCCCACTGGCAGCTTTCCACAGAATTTGCATTTAGAGGAGCAGAATGACATCACTGTCCTTTGGGAGTAGGTCCTCTGAAAAGG CAGCAGGTTCCAGCAGGTAGCTGAGCTGAGAGGACATATGGCCCACGGGGACCTACAGACAGCCTTTGACATTTGTATTTCTTACAATGG AGGGCCAAGGAGGGCAAGGGGCTGTGGAGTTTGGTGTCTACTAGTGTGTATGAATTTGAGCTAGAGTCCTTCTGTGGCATGCACTTTGAC CACTCCTGGCAGTCACATGGCAGATTTCCAAGTGCAAATCCTTAATCCAAACAAGGATCATCTAATGACACCACCAGGCCAATCCCTGCT CTCCTCCCCGAAAAGTCAGGGTCCCTTCATTGGAATCCTCCACCCACCCAAGCAGAATTTAGCAGAGATTTGCCTTCAAACCCTAACGGC CCCCTTGTTCTCTGGTCCTTCTCAAACCCACCTTTGTAGGCCACCCAGCATTGCAGGACAGCGTGTGGGGCAGCTGGACCTGTGCTTCCT GCCTGGGAGTCTCCCTTGGAATTCATCCTGACTCCTTCTAATAAAAATGGATGGGAAAGCAAAACACTTTGCCTTCTAAAGGCCGTATAC CAAGTATGCTTAGATAAATAAGCCACTTTTCTATTACTTAAGTAAGAAGGAAGTAGTAATTGATACTATTTATTGTTTGTGTGTGGTAGC TTGAAGCACACCACTGTCCATTTATTTGTAAGTGTAAAATATGTGTGTTTGTTTCAGCAGCACTTAAAAAAGCCAGTGTCTGGTTACACA TTTCAATTTTAATTAATTGACATAAAAATGCTACCGCCAGTGCCAGCTGCATCCTATTTAATTAAAAAGGTACTATATTTGTACATTATT TTTTAATGTTAAAAGGGCTTTTTTAAGTTTACAGTACACATACCGAGTGACTTTAGGGATGCTTTTGTGTTGAAATGTTACTATAGTGGC TGCAGGCAGCAACCCAGAAACACTTTAGAAGCTTTTTTTCCTTGGGAAAAATTCAAGCACTTCTTCCCTCCACCCTCACTCCAACCACCC CAATGGGGGTAATTCACATTTCTTAGAACAAATTCTGCCCTTTTTTGGTCTAGGGATTAAAATTTTGTTTTTCTTTCTTTCTTTTTTTTT TTTTTTCACTGAACCCTTAATTTGCACTGGGTCATGTGTTTGATTTGTGATTTCAAGACCAAAGCAAAGTCTTACTACTACTGTGGAACC ATGTACTAGTTCCTGGGAATTAAAATAGCGTGGTTCTCTTTGTAGCACAAACATTGCTGGAATTTGCAGTCTTTTCAATGCAGCCACATT TTTATCCATTTCAGTTGTCTCACAAATTTTAACCCATATCAGAGTTCCAGAACAGGTACCACAGCTTTGGTTTTAGATTAGTGGAATAAC ATTCAGCCCAGAACTGAGAAACTCAACAGATTAACTATCGTTTGCTCTTTAGACGGTCTCACTGCCTCTCACTTGCCAGAGCCCTTTCAA AATGAGCAGAGAAGTCCACACCATTAGGGACCATCTGTGATAAATTCAGAAGGGAGGAGATGTGTGTACAGCTTTAAGGATTCCCTCAAT TCCGAGGAAAGGGACTGGCCCAGAATCCAGGTTAATACATGGAAACACGAAGCATTAGCAAAAGTAATAATTATACCTATGGTATTTGAA AGAACAATAATAAAAGACACTTCTTCCAAACCTTGAATTTGTTGTTTTTAGAAAACGAATGCATTTAAAAATATTTTCTATGTGAGAATT TTTTAGATGTGTGTTTACTTCATGTTTACAAATAACTGTTTGCTTTTTAATGCAGTACTTTGAAATATATCAGCCAAAACCATAACTTAC AATAATTTCTTAGGTATTCTGAATAAAATTCCATTTCTTTTGGATATGCTTTACCATTCTTAGGTTTCTGTGGAACAAAAATATTTGTAG CATTTTGTGTAAATACAAGCTTTCATTTTTATTTTTTCCAATTGCTATTGCCCAAGAATTGCTTTCCATGCACATATTGTAAAAATTCCG CTTTGTGCCACAGGTCATGATTGTGGATGAGTTTACTCTTAACTTCAAAGGGACTATTTGTATTGTATGTTGCAACTGTAAATTGAATTA >In-frame_KCNK5_ENST00000359534_chr6_39161945_-_RUNX2_ENST00000359524_chr6_45479983_+_5454nt AGCGACGCGTGGAGAAGCGGCCCACGTGTCTGCCCAGAGTCAAGTCCTGTGTTCTTCCCGCTCCTTACGCATCCGCGGTCCAGGGCGCCC TTTCAGCCCCGCTGGTGTTCGCCCACCCCGGGCCGCGTGAGTGGGGCCCCACGCAGCTCCCCGCACTCCGTGGGCCAACTTGGCCAAGCA ACTCTGTCCGGGGAGCGGTGCTTGCGGGGGGTGAGTACCGGGCACTGCGCATGCGGAGCTCCAAATTCAAACAGCTGTTTTCAGAGGCTG GAGGGCGGGCGGACTGGTAGCAGCTGGGGCTAGGAGAGGCTTTCTCTAGGAGGCGGCCGCTCGGGAGCCATGGTGGACCGGGGCCCTCTG CTCACCTCGGCCATCATCTTCTACCTGGCCATCGGGGCGGCGATCTTCGAAGTGCTGGAGGAGCCACACTGGAAGGAGGCCAAGAAAAAC TACTACACACAGAAGCTGCATCTGCTCAAGGAGTTCCCGTGCCTGGGTCAGGAGGGCCTGGACAAGATCCTAGAGGTGGTATCTGATGCT GCAGGACAGGGTGTGGCCATCACAGGGAACCAGACCTTCAACAACTGGAACTGGCCCAATGCAATGATTTTTGCAGCGACCGTCATTACC ACCATTGGATATGGCAATGTGGCTCCCAAGACCCCCGCCGGTCGCCTCTTCTGTGTTTTCTATGGTCTCTTCGGGGTGCCGCTCTGCCTG ACGTGGATCAGTGCCCTGGGCAAGTTCTTCGGGGGACGTGCCAAGAGACTAGGGCAGTTCCTTACCAAGAGAGGTGTGAGTCTGCGGAAG GCGCAGATCACGTGCACAGTCATCTTCATCGTGTGGGGCGTCCTAGTCCACCTGGTGATCCCACCCTTCGTATTCATGGTGACTGAGGGG TGGAACTACATCGAGGGCCTCTACTACTCCTTCATCACCATCTCCACCATCGGCTTCGGTGACTTTGTGGCCGACCCCAGGCAGGCACAG TCTTCCCCGCCGTGGTCCTATGACCAGTCTTACCCCTCCTACCTGAGCCAGATGACGTCCCCGTCCATCCACTCTACCACCCCGCTGTCT TCCACACGGGGCACTGGGCTTCCTGCCATCACCGATGTGCCTAGGCGCATTTCAGATGATGACACTGCCACCTCTGACTTCTGCCTCTGG CCTTCCACTCTCAGTAAGAAGAGCCAGGCAGGTGCTTCAGAACTGGGCCCTTTTTCAGACCCCAGGCAGTTCCCAAGCATTTCATCCCTC ACTGAGAGCCGCTTCTCCAACCCACGAATGCACTATCCAGCCACCTTTACTTACACCCCGCCAGTCACCTCAGGCATGTCCCTCGGTATG TCCGCCACCACTCACTACCACACCTACCTGCCACCACCCTACCCCGGCTCTTCCCAAAGCCAGAGTGGACCCTTCCAGACCAGCAGCACT CCATATCTCTACTATGGCACTTCGTCAGGATCCTATCAGTTTCCCATGGTGCCGGGGGGAGACCGGTCTCCTTCCAGAATGCTTCCGCCA TGCACCACCACCTCGAATGGCAGCACGCTATTAAATCCAAATTTGCCTAACCAGAATGATGGTGTTGACGCTGATGGAAGCCACAGCAGT TCCCCAACTGTTTTGAATTCTAGTGGCAGAATGGATGAATCTGTTTGGCGACCATATTGAAATTCCTCAGCAGTGGCCCAGTGGTATCTG GGGGCCACATCCCACACGTATCAATATATACATATATAGAGAGAGTGCATATATATGTATATCGATTAGCTATCTACAAAGTGCCTATTT TTTAGAAGATTTTTCATTCACTCACTCAGTCATGATCTTGCAGCCATAAGAGGGTAGATATTGAGAAGCAGAAGGCTCAAGAGAGACAAT TGCAATCGAGCTTCAGATTGTTTACTATTTAAGATGTACTTTTACAAAGGAACAAAGAAGGGAAAAGGTATTTTTGTTTTTGTTGTTTGG TCTGTTATCATCAATAACCTGTTCATATGCCAATTCAGAGAGGTGGACTCCAGGTTCAGGAGGGAGAAGAGCAAAGCCGCTTCCTCTCTG TGCTTTGAAACTTCACACCCTCACGGTGGCAGCTGTGTATGGACCAGTGCCCTCCGCAGACAGCTCACAAAACCAGTTGAGGTGCACTAA AGGGACATGAGGTAGAATGGATGCTTCCATCACAGTACCATCATTCAGAATAACTCTTCCAATTTCTGCTTTCAGACATGCTGCAGGTCC TCATCTGAACTGTTGGGTTCGTTTTTTTTTTTTTTTTTCCTGCTCCAAGAAAGTGACTTCAAAAATAACTGATCAGGATAGATTATTTTA TTTTACTTTTTAACACTCCTTCTCCCCTTTTCCCACTGAACCAAAAAGAAATCCCATCCCTAAAACCTGCCTTCTCCTTTTATGCAAAAC TGAAAATGGCAATACATTATTATAGCCATAATGGTATAGATAGTGATTGCGTTTGGCTATGTGTTGTTTTCTTTTTTTTTAAATTATGAA TATGTGTAAAATCTGAGGTAACTTGCTAACGTGAATGGTCATATAACTTTAAAGATATATTTATAATTATTTAATGACATTTGGACCCTT GAAACATTTCTTAGTGTATTGATATGTTGACTTCGGTCTCTAAAAGTGCTCTTTATTAAATAACAAATTTCTTCAGTGGTCTAGAGCCAT ATCTGAAATATTGCTAAGCAATTTCAGTTCATCCAGGCACAATGTGATTTTAAAAAATACTTCCATCTCCAAATATTTTAGATATAGATT GTTTTTGTGATGTATGAAGGAAATGTTATGTTTAGTTCTTTCAGATCTTTGAATGCCTCTAACACAGCTTTGCCTTCTAAAGCGGTAATT AGGGATTTAAAAAACAACCTTTAGCCCTTTATCAGCATGAAATGCTGGAGTGATGTGGTTTTCTAATTTCTTTGGGGTAATTATGACTCT TGTCATATTAAAAAGACAAGCACAAGTAAATCATTGAACTACAGAAAAATGTTCTGTGGTTTCATAGTTAAGCAAAACTCTAAATCGCCA GGCTTCATAGCAAAGACATAGTCAGCTAAAAGCCGCACATGTGGATAGAGGGTTCAATTATGAGACACCTAGTACAGGAGAGCAAAATTG CACCAGAGATTCTTAACCAACCAGCCTTACCAAACAACACAACAGGGGAACCCCAATCTGCCTTACCCAAGGCCCCACTGGCAGCTTTCC ACAGAATTTGCATTTAGAGGAGCAGAATGACATCACTGTCCTTTGGGAGTAGGTCCTCTGAAAAGGCAGCAGGTTCCAGCAGGTAGCTGA GCTGAGAGGACATATGGCCCACGGGGACCTACAGACAGCCTTTGACATTTGTATTTCTTACAATGGAGGGCCAAGGAGGGCAAGGGGCTG TGGAGTTTGGTGTCTACTAGTGTGTATGAATTTGAGCTAGAGTCCTTCTGTGGCATGCACTTTGACCACTCCTGGCAGTCACATGGCAGA TTTCCAAGTGCAAATCCTTAATCCAAACAAGGATCATCTAATGACACCACCAGGCCAATCCCTGCTCTCCTCCCCGAAAAGTCAGGGTCC CTTCATTGGAATCCTCCACCCACCCAAGCAGAATTTAGCAGAGATTTGCCTTCAAACCCTAACGGCCCCCTTGTTCTCTGGTCCTTCTCA AACCCACCTTTGTAGGCCACCCAGCATTGCAGGACAGCGTGTGGGGCAGCTGGACCTGTGCTTCCTGCCTGGGAGTCTCCCTTGGAATTC ATCCTGACTCCTTCTAATAAAAATGGATGGGAAAGCAAAACACTTTGCCTTCTAAAGGCCGTATACCAAGTATGCTTAGATAAATAAGCC ACTTTTCTATTACTTAAGTAAGAAGGAAGTAGTAATTGATACTATTTATTGTTTGTGTGTGGTAGCTTGAAGCACACCACTGTCCATTTA TTTGTAAGTGTAAAATATGTGTGTTTGTTTCAGCAGCACTTAAAAAAGCCAGTGTCTGGTTACACATTTCAATTTTAATTAATTGACATA AAAATGCTACCGCCAGTGCCAGCTGCATCCTATTTAATTAAAAAGGTACTATATTTGTACATTATTTTTTAATGTTAAAAGGGCTTTTTT AAGTTTACAGTACACATACCGAGTGACTTTAGGGATGCTTTTGTGTTGAAATGTTACTATAGTGGCTGCAGGCAGCAACCCAGAAACACT TTAGAAGCTTTTTTTCCTTGGGAAAAATTCAAGCACTTCTTCCCTCCACCCTCACTCCAACCACCCCAATGGGGGTAATTCACATTTCTT AGAACAAATTCTGCCCTTTTTTGGTCTAGGGATTAAAATTTTGTTTTTCTTTCTTTCTTTTTTTTTTTTTTTCACTGAACCCTTAATTTG CACTGGGTCATGTGTTTGATTTGTGATTTCAAGACCAAAGCAAAGTCTTACTACTACTGTGGAACCATGTACTAGTTCCTGGGAATTAAA ATAGCGTGGTTCTCTTTGTAGCACAAACATTGCTGGAATTTGCAGTCTTTTCAATGCAGCCACATTTTTATCCATTTCAGTTGTCTCACA AATTTTAACCCATATCAGAGTTCCAGAACAGGTACCACAGCTTTGGTTTTAGATTAGTGGAATAACATTCAGCCCAGAACTGAGAAACTC AACAGATTAACTATCGTTTGCTCTTTAGACGGTCTCACTGCCTCTCACTTGCCAGAGCCCTTTCAAAATGAGCAGAGAAGTCCACACCAT TAGGGACCATCTGTGATAAATTCAGAAGGGAGGAGATGTGTGTACAGCTTTAAGGATTCCCTCAATTCCGAGGAAAGGGACTGGCCCAGA ATCCAGGTTAATACATGGAAACACGAAGCATTAGCAAAAGTAATAATTATACCTATGGTATTTGAAAGAACAATAATAAAAGACACTTCT TCCAAACCTTGAATTTGTTGTTTTTAGAAAACGAATGCATTTAAAAATATTTTCTATGTGAGAATTTTTTAGATGTGTGTTTACTTCATG TTTACAAATAACTGTTTGCTTTTTAATGCAGTACTTTGAAATATATCAGCCAAAACCATAACTTACAATAATTTCTTAGGTATTCTGAAT AAAATTCCATTTCTTTTGGATATGCTTTACCATTCTTAGGTTTCTGTGGAACAAAAATATTTGTAGCATTTTGTGTAAATACAAGCTTTC ATTTTTATTTTTTCCAATTGCTATTGCCCAAGAATTGCTTTCCATGCACATATTGTAAAAATTCCGCTTTGTGCCACAGGTCATGATTGT GGATGAGTTTACTCTTAACTTCAAAGGGACTATTTGTATTGTATGTTGCAACTGTAAATTGAATTATTTGGCATTTTTCTCATGATTGTA |
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FusionGenePPI for KCNK5_RUNX2 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| KCNK5 | APP, FRAT1 | RUNX2 | HDAC3, KAT6B, HDAC6, ALYREF, SMAD1, SMAD3, YAP1, JUN, FOS, ETS1, SMAD2, SMAD5, MSX2, STUB1, TLE1, HDAC4, HDAC5, KAT2B, HDAC1, EP300, BMPR1A, HES1, XRCC6, XRCC5, CREBBP, HDAC7, NR0B2, SOX9, RBM14, STAT3, SUV39H1, UBTF, FHL2, HIVEP3, WWP1, SMURF2, SMURF1, HIF1A, PML, RB1, TP53, CBFB, STAT5A, FBXW7, SKP2 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| Tgene | RUNX2 | chr6:39161945 | chr6:45479983 | ENST00000359524 | + | 3 | 7 | 336_439 | 272 | 508 | KAT6A |
| Tgene | RUNX2 | chr6:39161945 | chr6:45479983 | ENST00000371436 | + | 4 | 7 | 336_439 | 286 | 500 | KAT6A |
| Tgene | RUNX2 | chr6:39161945 | chr6:45479983 | ENST00000371438 | + | 4 | 8 | 336_439 | 286 | 522 | KAT6A |
| Tgene | RUNX2 | chr6:39161945 | chr6:45479983 | ENST00000465038 | + | 5 | 9 | 336_439 | 286 | 522 | KAT6A |
| Tgene | RUNX2 | chr6:39161945 | chr6:45479983 | ENST00000359524 | + | 3 | 7 | 374_468 | 272 | 508 | KAT6B |
| Tgene | RUNX2 | chr6:39161945 | chr6:45479983 | ENST00000371436 | + | 4 | 7 | 374_468 | 286 | 500 | KAT6B |
| Tgene | RUNX2 | chr6:39161945 | chr6:45479983 | ENST00000371438 | + | 4 | 8 | 374_468 | 286 | 522 | KAT6B |
| Tgene | RUNX2 | chr6:39161945 | chr6:45479983 | ENST00000465038 | + | 5 | 9 | 374_468 | 286 | 522 | KAT6B |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for KCNK5_RUNX2 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for KCNK5_RUNX2 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | KCNK5 | C0038220 | Status Epilepticus | 1 | CTD_human |
| Tgene | RUNX2 | C0008928 | Cleidocranial Dysplasia | 12 | CTD_human;ORPHANET;UNIPROT |
| Tgene | RUNX2 | C0029463 | Osteosarcoma | 2 | CTD_human |
| Tgene | RUNX2 | C0003872 | Arthritis, Psoriatic | 1 | CTD_human |
| Tgene | RUNX2 | C0003873 | Rheumatoid Arthritis | 1 | CTD_human |
| Tgene | RUNX2 | C0029408 | Degenerative polyarthritis | 1 | CTD_human |
| Tgene | RUNX2 | C0040427 | Tooth Abnormalities | 1 | CTD_human |
| Tgene | RUNX2 | C0041948 | Uremia | 1 | CTD_human |
| Tgene | RUNX2 | C0243057 | Stomatognathic System Abnormalities | 1 | CTD_human |
| Tgene | RUNX2 | C0376634 | Craniofacial Abnormalities | 1 | CTD_human |
| Tgene | RUNX2 | C0949690 | Spondylarthritis | 1 | CTD_human |
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