|
||||||
|
 | |
| |
| |
| |
| |
|
Fusion gene ID: 18281 |
FusionGeneSummary for KCNK17_DNAH8 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: KCNK17_DNAH8 | Fusion gene ID: 18281 | Hgene | Tgene | Gene symbol | KCNK17 | DNAH8 | Gene ID | 89822 | 1769 |
| Gene name | potassium two pore domain channel subfamily K member 17 | dynein axonemal heavy chain 8 | |
| Synonyms | K2p17.1|TALK-2|TALK2|TASK-4|TASK4 | ATPase|hdhc9 | |
| Cytomap | 6p21.2 | 6p21.2 | |
| Type of gene | protein-coding | protein-coding | |
| Description | potassium channel subfamily K member 172P domain potassium channel Talk-2TWIK-related acid-sensitive K(+) channel 4TWIK-related alkaline pH-activated K(+) channel 2acid-sensitive potassium channel protein TASK-4potassium channel, two pore domain subf | dynein heavy chain 8, axonemalaxonemal beta dynein heavy chain 8ciliary dynein heavy chain 8dynein, axonemal, heavy polypeptide 8 | |
| Modification date | 20180523 | 20180523 | |
| UniProtAcc | Q96T54 | Q96JB1 | |
| Ensembl transtripts involved in fusion gene | ENST00000373231, ENST00000453413, | ENST00000449981, ENST00000359357, ENST00000441566, | |
| Fusion gene scores | * DoF score | 1 X 1 X 1=1 | 8 X 7 X 5=280 |
| # samples | 1 | 7 | |
| ** MAII score | log2(1/1*10)=3.32192809488736 | log2(7/280*10)=-2 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: KCNK17 [Title/Abstract] AND DNAH8 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | KCNK17 | GO:0006813 | potassium ion transport | 11248242 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | BLCA | TCGA-DK-AA6U-01A | KCNK17 | chr6 | 39271733 | - | DNAH8 | chr6 | 38889145 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| Frame-shift | ENST00000373231 | ENST00000449981 | KCNK17 | chr6 | 39271733 | - | DNAH8 | chr6 | 38889145 | + |
| Frame-shift | ENST00000373231 | ENST00000359357 | KCNK17 | chr6 | 39271733 | - | DNAH8 | chr6 | 38889145 | + |
| Frame-shift | ENST00000373231 | ENST00000441566 | KCNK17 | chr6 | 39271733 | - | DNAH8 | chr6 | 38889145 | + |
| In-frame | ENST00000453413 | ENST00000449981 | KCNK17 | chr6 | 39271733 | - | DNAH8 | chr6 | 38889145 | + |
| In-frame | ENST00000453413 | ENST00000359357 | KCNK17 | chr6 | 39271733 | - | DNAH8 | chr6 | 38889145 | + |
| In-frame | ENST00000453413 | ENST00000441566 | KCNK17 | chr6 | 39271733 | - | DNAH8 | chr6 | 38889145 | + |
Top |
FusionProtFeatures for KCNK17_DNAH8 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| KCNK17 | DNAH8 |
| Outward rectifying potassium channel. Produces rapidlyactivating and non-inactivating outward rectifier K(+) currents. | Force generating protein of respiratory cilia. Producesforce towards the minus ends of microtubules. Dynein has ATPaseactivity; the force-producing power stroke is thought to occur onrelease of ADP. Involved in sperm motility; implicated in spermflagellar assembly (By similarity). {ECO:0000250}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
Top |
FusionGeneSequence for KCNK17_DNAH8 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_KCNK17_ENST00000453413_chr6_39271733_-_DNAH8_ENST00000449981_chr6_38889145_+_910aa MYRPRARAAPEGRVRGCAVPSTVLLLLAYLAYLALGTGVFWTLEGRAAQDSSRSFQRDKWELLQNFTCLDRPALDSLIRDVVQAYKNGAS LLSNTTSMGRWELVGSFFFSVSTITTIGYGNLSPNTMAARLFCIFFALVGIPLNLVVLNRLGHLMQQGVNHWASRLGGTWQDPDKARWLA GSGALLSGLLLFLLLPPLLFSHMEGWSYTEGFYFAFITLSTVGFGDYVIGQPGQAGRPVSSCXCXVREGTSPAGXEASXAGXSTGKIXCS NEXENGFAXXRXYVPEKDAGRLHSHRWAEWRKNPVDPAKXRIQSSDXXTCRXYSAVHGIPFLPWSFQSDIXELFAXRSMGNGVESTENSF HRKPESYFNVGGSSNYWXVGATGITRRXSLNSEWHYCDKGHQIPTPHRPTNSRQNLDXIKGKRKXFTGDISEPXIFSHTLGGQPFLGPTP SHXGHSXRAGSSLGXCIRKEFYXIWHHFQGESRXXGMXYHGYIXTLHYYEVTKSCLYPRDXCXNVSHXFHCYNERTXESVTKESHSNRET GVRGXEGXTFGGCYFXXAEDERTXRXPPLXIKCYKRLIGRXRISHWCTSNYQADSSXGKXKVACGCRNXDQDQRGSGGVPARSHPRKHPL LPHHRDEHGQHHVSDVIGPVLEVIXPVHGQIXKVTTTSKENYKYYRVPDIXSFYILCQRPIRKPQIPVCTPHDLKDXPSERDSXAQRVSS SHXRGSSSGPESLSSQTLSLDPXHDLAESCGAEXTSTICRNYEPDISXXEGVEKLVXXRCSRGGNYPXWIXXFTRYLPXTFTYQVLVPRP YCFSSKKVYCRFFGGEVHRTSYLKSGENLGRKXYPDTSDMLPVHGIXPHQSNXCIGQETETGMXNYLNGARTRSTCSKADSDVNAAGMXQ >In-frame_KCNK17_ENST00000453413_chr6_39271733_-_DNAH8_ENST00000359357_chr6_38889145_+_1429aa MYRPRARAAPEGRVRGCAVPSTVLLLLAYLAYLALGTGVFWTLEGRAAQDSSRSFQRDKWELLQNFTCLDRPALDSLIRDVVQAYKNGAS LLSNTTSMGRWELVGSFFFSVSTITTIGYGNLSPNTMAARLFCIFFALVGIPLNLVVLNRLGHLMQQGVNHWASRLGGTWQDPDKARWLA GSGALLSGLLLFLLLPPLLFSHMEGWSYTEGFYFAFITLSTVGFGDYVIGQPGQAGRPVSSCXCXVREGTSPAGXEASXAGXSTGKIXCS NEXENGFAXXRXYVPEKDAGRLHSHRWAEWRKNPVDPAKXRIQSSDXXTCRXYSAVHGIPFLPWSFQSDIXELFAXRSMGNGVESTENSF HRKPESYFNVGGSSNYWXVGATGITRRXSLNSEWHYCDKGHQIPTPHRPTNSRQNLDXIKGKRKXFTGDISEPXIFSHTLGGQPFLGPTP SHXGHSXRAGSSLGXCIRKEFYXIWHHFQGESRXXGMXYHGYIXTLHYYEVTKSCLYPRDXCXNVSHXFHCYNERTXESVTKESHSNRET GVRGXEGXTFGGCYFXXAEDERTXRXPPLXIKCYKRLIGRXRISHWCTSNYQADSSXGKXKVACGCRNXDQDQRGSGGVPARSHPRKHPL LPHHRDEHGQHHVSDVIGPVLEVIXPVHGQIXKVTTTSKENYKYYRVPDIXSFYILCQRPIRKPQIPVCTPHDLKDXPSERDSXAQRVSS SHXRGSSSGPESLSSQTLSLDPXHDLAESCGAEXTSTICRNYEPDISXXEGVEKLVXXRCSRGGNYPXWIXXFTRYLPXTFTYQVLVPRP YCFSSKKVYCRFFGGEVHRTSYLKSGENLGRKXYPDTSDMLPVHGIXPHQSNXCIGQETETGMXNYLNGARTRSTCSKADSDVNAAGWLG ITTKLPPWPGIHGRITRDANYHXSQXXFFPSMDNYGAPXSISNYIASDLSQIHXXATPRCTRRFEKNICWNXSRPSGHQXFTHVEADALH SSIFTLHCAGATKIWPLRMEYSLRIQFCXLFSQCSVYSESPXXMRYXERCIMEYGSVHDRRSTIWRQSDRXLXQTSTXLLCQSLVQXEDV XTVILLLYWIXNPLMQNLRPVFXIHPVTAIPRXPXSLWASPXCXYHVSEXHCFCCSXNNYQHSTQREWRWCGRDPGGYCLXIIXRYAEXT PSXLHSSXGEISFDKDGPSXFNEHISXTRNXQNAKSHFNTPQXPEXSKIGHXRNNHYEXESERCSGQHVXCSYTSALEKSVLGFVHTGLL VHXTFGKKCSVFYVDIXREAXCVLDDWFLXSPRLPHSNEARSDPCPQRLGTGHCDHPQXSSETDQGGDHVTPWGRCVYLWALHGWSSLGQ >In-frame_KCNK17_ENST00000453413_chr6_39271733_-_DNAH8_ENST00000441566_chr6_38889145_+_1429aa MYRPRARAAPEGRVRGCAVPSTVLLLLAYLAYLALGTGVFWTLEGRAAQDSSRSFQRDKWELLQNFTCLDRPALDSLIRDVVQAYKNGAS LLSNTTSMGRWELVGSFFFSVSTITTIGYGNLSPNTMAARLFCIFFALVGIPLNLVVLNRLGHLMQQGVNHWASRLGGTWQDPDKARWLA GSGALLSGLLLFLLLPPLLFSHMEGWSYTEGFYFAFITLSTVGFGDYVIGQPGQAGRPVSSCXCXVREGTSPAGXEASXAGXSTGKIXCS NEXENGFAXXRXYVPEKDAGRLHSHRWAEWRKNPVDPAKXRIQSSDXXTCRXYSAVHGIPFLPWSFQSDIXELFAXRSMGNGVESTENSF HRKPESYFNVGGSSNYWXVGATGITRRXSLNSEWHYCDKGHQIPTPHRPTNSRQNLDXIKGKRKXFTGDISEPXIFSHTLGGQPFLGPTP SHXGHSXRAGSSLGXCIRKEFYXIWHHFQGESRXXGMXYHGYIXTLHYYEVTKSCLYPRDXCXNVSHXFHCYNERTXESVTKESHSNRET GVRGXEGXTFGGCYFXXAEDERTXRXPPLXIKCYKRLIGRXRISHWCTSNYQADSSXGKXKVACGCRNXDQDQRGSGGVPARSHPRKHPL LPHHRDEHGQHHVSDVIGPVLEVIXPVHGQIXKVTTTSKENYKYYRVPDIXSFYILCQRPIRKPQIPVCTPHDLKDXPSERDSXAQRVSS SHXRGSSSGPESLSSQTLSLDPXHDLAESCGAEXTSTICRNYEPDISXXEGVEKLVXXRCSRGGNYPXWIXXFTRYLPXTFTYQVLVPRP YCFSSKKVYCRFFGGEVHRTSYLKSGENLGRKXYPDTSDMLPVHGIXPHQSNXCIGQETETGMXNYLNGARTRSTCSKADSDVNAAGWLG ITTKLPPWPGIHGRITRDANYHXSQXXFFPSMDNYGAPXSISNYIASDLSQIHXXATPRCTRRFEKNICWNXSRPSGHQXFTHVEADALH SSIFTLHCAGATKIWPLRMEYSLRIQFCXLFSQCSVYSESPXXMRYXERCIMEYGSVHDRRSTIWRQSDRXLXQTSTXLLCQSLVQXEDV XTVILLLYWIXNPLMQNLRPVFXIHPVTAIPRXPXSLWASPXCXYHVSEXHCFCCSXNNYQHSTQREWRWCGRDPGGYCLXIIXRYAEXT PSXLHSSXGEISFDKDGPSXFNEHISXTRNXQNAKSHFNTPQXPEXSKIGHXRNNHYEXESERCSGQHVXCSYTSALEKSVLGFVHTGLL VHXTFGKKCSVFYVDIXREAXCVLDDWFLXSPRLPHSNEARSDPCPQRLGTGHCDHPQXSSETDQGGDHVTPWGRCVYLWALHGWSSLGQ |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_KCNK17_ENST00000453413_chr6_39271733_-_DNAH8_ENST00000449981_chr6_38889145_+_2731nt ATGTACCGACCGCGAGCCCGGGCGGCTCCCGAGGGCAGGGTCCGGGGCTGCGCGGTGCCCAGCACCGTGCTCCTGCTGCTCGCCTACCTG GCTTACCTGGCGCTGGGCACCGGCGTGTTCTGGACGCTGGAGGGCCGCGCGGCGCAGGACTCCAGCCGCAGCTTCCAGCGCGACAAGTGG GAGCTGTTGCAGAACTTCACGTGTCTGGACCGCCCGGCGCTGGACTCGCTGATCCGGGATGTCGTCCAAGCATACAAAAACGGAGCCAGC CTCCTCAGCAACACCACCAGCATGGGGCGCTGGGAGCTCGTGGGCTCCTTCTTCTTTTCTGTGTCCACCATCACCACCATTGGCTATGGC AACCTGAGCCCCAACACGATGGCTGCCCGCCTCTTCTGCATCTTCTTTGCCCTTGTGGGGATCCCACTCAACCTCGTGGTGCTCAACCGA CTGGGGCATCTCATGCAGCAGGGAGTAAACCACTGGGCCAGCAGGCTGGGGGGCACCTGGCAGGATCCTGACAAGGCGCGGTGGCTGGCG GGCTCTGGCGCCCTCCTCTCGGGCCTCCTGCTCTTCCTGCTGCTGCCACCGCTGCTCTTCTCCCACATGGAGGGCTGGAGCTACACAGAG GGCTTCTACTTCGCCTTCATCACCCTCAGCACCGTGGGCTTCGGCGACTACGTGATTGGCCAACCTGGCCAAGCAGGAAGGCCGGTTAGC AGTTGCTAATGCTGAGTTAGGGAAGGCACAAGCCCTGCTGGATGAGAAGCAAGCTGAGCTGGATAAAGTACAGGCAAAATTTGATGCAGC AATGAATGAGAAAATGGATTTGCTTAATGACGCTGATACGTGCCGGAAAAAGATGCAGGCCGCCTCCACTCTCATCGATGGGCTGAGTGG AGAAAAAATCCGGTGGACCCAGCAAAGTAAAGAATTCAAAGCTCAGATTAATAGACTTGTAGGTGATATTCTGCTGTGCACGGGATTCCT TTCCTACCTTGGTCCTTTCAATCAGATATTTAGGAACTATTTGCTTAAAGATCAATGGGAAATGGAGTTGAGAGCACGGAAAATTCCTTT CACAGAAAACCTGAATCTTATTTCAATGTTGGTGGATCCTCCAACTATTGGTGAGTGGGGGCTACAGGGATTACCAGGAGATGATCTCTC AATTCAGAATGGCATTATTGTGACAAAGGCCACCAGATACCCACTCCTCATAGACCCACAAACTCAAGGCAAAACTTGGATTAAATCAAA GGAAAAAGAAAATGATTTACAGGTGACATCTCTGAACCATAAATATTTTCGCACACACTTGGAGGACAGCCTTTCCTTGGGCCGACCCCT TCTCATTGAGGACATTCATGAAGAGCTGGATCCAGCCTTGGATAATGTATTAGAAAAGAATTTTATTAAATCTGGCACCACTTTCAAGGT GAAAGTCGGTGATAAGGAATGTGATATCATGGATACATTTAAACTTTACATTACTACGAAGTTACCAAATCCTGCCTTTACCCCAGAGAT TAATGCTAAAACGTCAGTCATTGATTTCACTGTTACAATGAAAGGACTTGAGAATCAGTTACTAAGGAGAGTCATTCTAACAGAGAAACA GGAGTTAGAGGCTGAGAGGGTTAAACTTTTGGAGGATGTTACTTTTAATAAGCGGAAGATGAAAGAACTTGAAGATAACCTCCTCTATAA ATTAAGTGCTACAAAAGGCTCATTGGTAGATGACGAATCTCTCATTGGTGTACTTCGAACTACCAAGCAGACAGCAGCTGAGGTAAGTGA AAAGTTGCATGTGGCTGCAGAAACTGAGATCAAGATCAACGCGGCTCAGGAGGAGTTCCGGCCCGCAGCCACCCGCGGAAGCATCCTCTA CTTCCTCATCACAGAGATGAGCATGGTCAACATCATGTATCAGACGTCATTGGCCCAGTTCTTGAAGTTATTTGACCAGTCCATGGCCAG ATCTGAAAAGTCACCACTACCTCAAAAGAGAATTACAAATATTATCGAGTACCTGACATATGAAGTTTTTACATACTCTGTCAGAGGCCT ATACGAAAACCACAAATTCCTGTTTGTACTCCTCATGACCTTAAAGATTGACCTTCAGAGAGGGACAGTTAAGCACAGAGAGTTTCAAGC TCTCATTAAAGGGGGAGCAGCTCTGGACCTGAAAGCCTGTCCTCCCAAACCCTATCGCTGGATCCTTGACATGACTTGGCTGAATCTTGT GGAGCTGAGTAAACTTCCACAATTTGCAGAAATTATGAACCAGATATCTCGTAATGAGAAGGGGTGGAAAAGCTGGTTTGATAAAGATGC TCCAGAGGAGGAAATTATCCCTGATGGATATAATGATTCACTAGATACCTGCCATAAACTTTTACTTATCAGGTCTTGGTGCCCAGACCG TACTGTTTTTCAAGCAAGAAAGTATATTGCAGATTCTTTGGAGGAGAAGTACACAGAACCAGTTATCTTAAATCTGGAGAAAACTTGGGA AGAAAGTGATACCCGGACACCTCTGATATGCTTCCTGTCCATGGGATCTGACCCCACCAATCAAATTGATGCATTGGCCAAGAAACTGAA ACTGGAATGTAGAACTATCTCAATGGGGCAAGGACAAGAAGTACATGCTCGAAAGCTGATTCAGATGTCAATGCAGCAGGTATGTGACAA >In-frame_KCNK17_ENST00000453413_chr6_39271733_-_DNAH8_ENST00000359357_chr6_38889145_+_4288nt ATGTACCGACCGCGAGCCCGGGCGGCTCCCGAGGGCAGGGTCCGGGGCTGCGCGGTGCCCAGCACCGTGCTCCTGCTGCTCGCCTACCTG GCTTACCTGGCGCTGGGCACCGGCGTGTTCTGGACGCTGGAGGGCCGCGCGGCGCAGGACTCCAGCCGCAGCTTCCAGCGCGACAAGTGG GAGCTGTTGCAGAACTTCACGTGTCTGGACCGCCCGGCGCTGGACTCGCTGATCCGGGATGTCGTCCAAGCATACAAAAACGGAGCCAGC CTCCTCAGCAACACCACCAGCATGGGGCGCTGGGAGCTCGTGGGCTCCTTCTTCTTTTCTGTGTCCACCATCACCACCATTGGCTATGGC AACCTGAGCCCCAACACGATGGCTGCCCGCCTCTTCTGCATCTTCTTTGCCCTTGTGGGGATCCCACTCAACCTCGTGGTGCTCAACCGA CTGGGGCATCTCATGCAGCAGGGAGTAAACCACTGGGCCAGCAGGCTGGGGGGCACCTGGCAGGATCCTGACAAGGCGCGGTGGCTGGCG GGCTCTGGCGCCCTCCTCTCGGGCCTCCTGCTCTTCCTGCTGCTGCCACCGCTGCTCTTCTCCCACATGGAGGGCTGGAGCTACACAGAG GGCTTCTACTTCGCCTTCATCACCCTCAGCACCGTGGGCTTCGGCGACTACGTGATTGGCCAACCTGGCCAAGCAGGAAGGCCGGTTAGC AGTTGCTAATGCTGAGTTAGGGAAGGCACAAGCCCTGCTGGATGAGAAGCAAGCTGAGCTGGATAAAGTACAGGCAAAATTTGATGCAGC AATGAATGAGAAAATGGATTTGCTTAATGACGCTGATACGTGCCGGAAAAAGATGCAGGCCGCCTCCACTCTCATCGATGGGCTGAGTGG AGAAAAAATCCGGTGGACCCAGCAAAGTAAAGAATTCAAAGCTCAGATTAATAGACTTGTAGGTGATATTCTGCTGTGCACGGGATTCCT TTCCTACCTTGGTCCTTTCAATCAGATATTTAGGAACTATTTGCTTAAAGATCAATGGGAAATGGAGTTGAGAGCACGGAAAATTCCTTT CACAGAAAACCTGAATCTTATTTCAATGTTGGTGGATCCTCCAACTATTGGTGAGTGGGGGCTACAGGGATTACCAGGAGATGATCTCTC AATTCAGAATGGCATTATTGTGACAAAGGCCACCAGATACCCACTCCTCATAGACCCACAAACTCAAGGCAAAACTTGGATTAAATCAAA GGAAAAAGAAAATGATTTACAGGTGACATCTCTGAACCATAAATATTTTCGCACACACTTGGAGGACAGCCTTTCCTTGGGCCGACCCCT TCTCATTGAGGACATTCATGAAGAGCTGGATCCAGCCTTGGATAATGTATTAGAAAAGAATTTTATTAAATCTGGCACCACTTTCAAGGT GAAAGTCGGTGATAAGGAATGTGATATCATGGATACATTTAAACTTTACATTACTACGAAGTTACCAAATCCTGCCTTTACCCCAGAGAT TAATGCTAAAACGTCAGTCATTGATTTCACTGTTACAATGAAAGGACTTGAGAATCAGTTACTAAGGAGAGTCATTCTAACAGAGAAACA GGAGTTAGAGGCTGAGAGGGTTAAACTTTTGGAGGATGTTACTTTTAATAAGCGGAAGATGAAAGAACTTGAAGATAACCTCCTCTATAA ATTAAGTGCTACAAAAGGCTCATTGGTAGATGACGAATCTCTCATTGGTGTACTTCGAACTACCAAGCAGACAGCAGCTGAGGTAAGTGA AAAGTTGCATGTGGCTGCAGAAACTGAGATCAAGATCAACGCGGCTCAGGAGGAGTTCCGGCCCGCAGCCACCCGCGGAAGCATCCTCTA CTTCCTCATCACAGAGATGAGCATGGTCAACATCATGTATCAGACGTCATTGGCCCAGTTCTTGAAGTTATTTGACCAGTCCATGGCCAG ATCTGAAAAGTCACCACTACCTCAAAAGAGAATTACAAATATTATCGAGTACCTGACATATGAAGTTTTTACATACTCTGTCAGAGGCCT ATACGAAAACCACAAATTCCTGTTTGTACTCCTCATGACCTTAAAGATTGACCTTCAGAGAGGGACAGTTAAGCACAGAGAGTTTCAAGC TCTCATTAAAGGGGGAGCAGCTCTGGACCTGAAAGCCTGTCCTCCCAAACCCTATCGCTGGATCCTTGACATGACTTGGCTGAATCTTGT GGAGCTGAGTAAACTTCCACAATTTGCAGAAATTATGAACCAGATATCTCGTAATGAGAAGGGGTGGAAAAGCTGGTTTGATAAAGATGC TCCAGAGGAGGAAATTATCCCTGATGGATATAATGATTCACTAGATACCTGCCATAAACTTTTACTTATCAGGTCTTGGTGCCCAGACCG TACTGTTTTTCAAGCAAGAAAGTATATTGCAGATTCTTTGGAGGAGAAGTACACAGAACCAGTTATCTTAAATCTGGAGAAAACTTGGGA AGAAAGTGATACCCGGACACCTCTGATATGCTTCCTGTCCATGGGATCTGACCCCACCAATCAAATTGATGCATTGGCCAAGAAACTGAA ACTGGAATGTAGAACTATCTCAATGGGGCAAGGACAAGAAGTACATGCTCGAAAGCTGATTCAGATGTCAATGCAGCAGGGTGGTTGGGT ATTACTACAAAATTGCCACCTTGGCCTGGAATTCATGGAAGAATTACTAGAGACGCTAATTACCACTGAAGCCAGTGATGATTCTTTCCG AGTATGGATAACTACGGAGCCCCATGATCGATTTCCAATTACATTGCTTCAGACCTCTCTCAAATTCACTAATGAGCCACCCCAAGGTGT ACGCGCAGGTTTGAAAAGAACATTTGCTGGAATTAATCAAGACCTTCTGGACATCAGTAATTTACCCATGTGGAAGCCGATGCTTTACAC AGTAGCATTTTTACACTCCACTGTGCAGGAGCGACGAAAATTTGGCCCCTTAGGATGGAATATTCCCTACGAATTCAATTCTGCTGACTT TTCAGCCAGTGTTCAGTTTATTCAGAATCACCTTGATGAATGCGATATTAAGAAAGGTGTATCATGGAATACGGTTCGGTACATGATCGG AGAAGTACAATATGGAGGCAGAGTGACAGATGACTTTGACAAACGTCTACTTAATTGCTTTGCCAGAGTCTGGTTCAGTGAGAAGATGTT TGAACCGTCATTCTGCTTTTATACTGGATATAAAATCCCCTTATGCAAAACCTTAGACCAGTATTTTGAATACATCCAGTCACTGCCATC CCTAGATAACCCTGAAGTCTTTGGGCTTCACCCTAATGCTGATATCACGTATCAGAGTAACACTGCTTCTGCTGTTCTTGAAACAATTAC CAACATTCAACCCAAAGAGAGTGGAGGTGGTGTGGGAGAGACCCGGGAGGCTATTGTTTATAGATTATCTGAAGATATGCTGAGTAAACT CCCTCCTGATTACATTCCTCATGAGGTGAAATCTCGTTTGATAAAGATGGGCCATCTTAATTCAATGAACATATTTCTTAGACAAGAAAT TGACAGAATGCAAAGAGTCATTTCAATACTCCGCAGTAGCCTGAGTGATCTAAAATTGGCCATTGAAGGAACAATCATTATGAGTGAGAA TCTGAGAGATGCTCTGGACAACATGTATGATGCTCGTATACCTCAGCTCTGGAAAAGAGTGTCTTGGGATTCGTCCACACTGGGCTTCTG GTTCACTGAACTTTTGGAAAGAAATGCTCAGTTTTCTACGTGGATATTTGAAGGGAGGCCTAATGTGTTTTGGATGACTGGTTTCTTTAA TCCCCAAGGCTTCCTCACAGCAATGAGGCAAGAAGTGACCCGTGCCCACAAAGGCTGGGCACTGGACACTGTGACCATCCACAATGAAGT TCTGAGACAGACCAAGGAGGAGATCACGTCACCCCCTGGGGAAGGTGTGTATATTTATGGGCTCTACATGGATGGAGCAGCCTGGGACAG ACGGAATGGGAAGCTCATGGAATCCACCCCCAAGGTACTCTTCACGCAGTTACCCGTGCTCCACATCTTTGCCATTAACTCCACGGCACC CAAGGACCCCAAGCTGTATGTGTGTCCTATTTACAAGAAACCCAGGCGAACTGATTTGACCTTCATCACTGTGGTATATTTACGAACAGT >In-frame_KCNK17_ENST00000453413_chr6_39271733_-_DNAH8_ENST00000441566_chr6_38889145_+_4288nt ATGTACCGACCGCGAGCCCGGGCGGCTCCCGAGGGCAGGGTCCGGGGCTGCGCGGTGCCCAGCACCGTGCTCCTGCTGCTCGCCTACCTG GCTTACCTGGCGCTGGGCACCGGCGTGTTCTGGACGCTGGAGGGCCGCGCGGCGCAGGACTCCAGCCGCAGCTTCCAGCGCGACAAGTGG GAGCTGTTGCAGAACTTCACGTGTCTGGACCGCCCGGCGCTGGACTCGCTGATCCGGGATGTCGTCCAAGCATACAAAAACGGAGCCAGC CTCCTCAGCAACACCACCAGCATGGGGCGCTGGGAGCTCGTGGGCTCCTTCTTCTTTTCTGTGTCCACCATCACCACCATTGGCTATGGC AACCTGAGCCCCAACACGATGGCTGCCCGCCTCTTCTGCATCTTCTTTGCCCTTGTGGGGATCCCACTCAACCTCGTGGTGCTCAACCGA CTGGGGCATCTCATGCAGCAGGGAGTAAACCACTGGGCCAGCAGGCTGGGGGGCACCTGGCAGGATCCTGACAAGGCGCGGTGGCTGGCG GGCTCTGGCGCCCTCCTCTCGGGCCTCCTGCTCTTCCTGCTGCTGCCACCGCTGCTCTTCTCCCACATGGAGGGCTGGAGCTACACAGAG GGCTTCTACTTCGCCTTCATCACCCTCAGCACCGTGGGCTTCGGCGACTACGTGATTGGCCAACCTGGCCAAGCAGGAAGGCCGGTTAGC AGTTGCTAATGCTGAGTTAGGGAAGGCACAAGCCCTGCTGGATGAGAAGCAAGCTGAGCTGGATAAAGTACAGGCAAAATTTGATGCAGC AATGAATGAGAAAATGGATTTGCTTAATGACGCTGATACGTGCCGGAAAAAGATGCAGGCCGCCTCCACTCTCATCGATGGGCTGAGTGG AGAAAAAATCCGGTGGACCCAGCAAAGTAAAGAATTCAAAGCTCAGATTAATAGACTTGTAGGTGATATTCTGCTGTGCACGGGATTCCT TTCCTACCTTGGTCCTTTCAATCAGATATTTAGGAACTATTTGCTTAAAGATCAATGGGAAATGGAGTTGAGAGCACGGAAAATTCCTTT CACAGAAAACCTGAATCTTATTTCAATGTTGGTGGATCCTCCAACTATTGGTGAGTGGGGGCTACAGGGATTACCAGGAGATGATCTCTC AATTCAGAATGGCATTATTGTGACAAAGGCCACCAGATACCCACTCCTCATAGACCCACAAACTCAAGGCAAAACTTGGATTAAATCAAA GGAAAAAGAAAATGATTTACAGGTGACATCTCTGAACCATAAATATTTTCGCACACACTTGGAGGACAGCCTTTCCTTGGGCCGACCCCT TCTCATTGAGGACATTCATGAAGAGCTGGATCCAGCCTTGGATAATGTATTAGAAAAGAATTTTATTAAATCTGGCACCACTTTCAAGGT GAAAGTCGGTGATAAGGAATGTGATATCATGGATACATTTAAACTTTACATTACTACGAAGTTACCAAATCCTGCCTTTACCCCAGAGAT TAATGCTAAAACGTCAGTCATTGATTTCACTGTTACAATGAAAGGACTTGAGAATCAGTTACTAAGGAGAGTCATTCTAACAGAGAAACA GGAGTTAGAGGCTGAGAGGGTTAAACTTTTGGAGGATGTTACTTTTAATAAGCGGAAGATGAAAGAACTTGAAGATAACCTCCTCTATAA ATTAAGTGCTACAAAAGGCTCATTGGTAGATGACGAATCTCTCATTGGTGTACTTCGAACTACCAAGCAGACAGCAGCTGAGGTAAGTGA AAAGTTGCATGTGGCTGCAGAAACTGAGATCAAGATCAACGCGGCTCAGGAGGAGTTCCGGCCCGCAGCCACCCGCGGAAGCATCCTCTA CTTCCTCATCACAGAGATGAGCATGGTCAACATCATGTATCAGACGTCATTGGCCCAGTTCTTGAAGTTATTTGACCAGTCCATGGCCAG ATCTGAAAAGTCACCACTACCTCAAAAGAGAATTACAAATATTATCGAGTACCTGACATATGAAGTTTTTACATACTCTGTCAGAGGCCT ATACGAAAACCACAAATTCCTGTTTGTACTCCTCATGACCTTAAAGATTGACCTTCAGAGAGGGACAGTTAAGCACAGAGAGTTTCAAGC TCTCATTAAAGGGGGAGCAGCTCTGGACCTGAAAGCCTGTCCTCCCAAACCCTATCGCTGGATCCTTGACATGACTTGGCTGAATCTTGT GGAGCTGAGTAAACTTCCACAATTTGCAGAAATTATGAACCAGATATCTCGTAATGAGAAGGGGTGGAAAAGCTGGTTTGATAAAGATGC TCCAGAGGAGGAAATTATCCCTGATGGATATAATGATTCACTAGATACCTGCCATAAACTTTTACTTATCAGGTCTTGGTGCCCAGACCG TACTGTTTTTCAAGCAAGAAAGTATATTGCAGATTCTTTGGAGGAGAAGTACACAGAACCAGTTATCTTAAATCTGGAGAAAACTTGGGA AGAAAGTGATACCCGGACACCTCTGATATGCTTCCTGTCCATGGGATCTGACCCCACCAATCAAATTGATGCATTGGCCAAGAAACTGAA ACTGGAATGTAGAACTATCTCAATGGGGCAAGGACAAGAAGTACATGCTCGAAAGCTGATTCAGATGTCAATGCAGCAGGGTGGTTGGGT ATTACTACAAAATTGCCACCTTGGCCTGGAATTCATGGAAGAATTACTAGAGACGCTAATTACCACTGAAGCCAGTGATGATTCTTTCCG AGTATGGATAACTACGGAGCCCCATGATCGATTTCCAATTACATTGCTTCAGACCTCTCTCAAATTCACTAATGAGCCACCCCAAGGTGT ACGCGCAGGTTTGAAAAGAACATTTGCTGGAATTAATCAAGACCTTCTGGACATCAGTAATTTACCCATGTGGAAGCCGATGCTTTACAC AGTAGCATTTTTACACTCCACTGTGCAGGAGCGACGAAAATTTGGCCCCTTAGGATGGAATATTCCCTACGAATTCAATTCTGCTGACTT TTCAGCCAGTGTTCAGTTTATTCAGAATCACCTTGATGAATGCGATATTAAGAAAGGTGTATCATGGAATACGGTTCGGTACATGATCGG AGAAGTACAATATGGAGGCAGAGTGACAGATGACTTTGACAAACGTCTACTTAATTGCTTTGCCAGAGTCTGGTTCAGTGAGAAGATGTT TGAACCGTCATTCTGCTTTTATACTGGATATAAAATCCCCTTATGCAAAACCTTAGACCAGTATTTTGAATACATCCAGTCACTGCCATC CCTAGATAACCCTGAAGTCTTTGGGCTTCACCCTAATGCTGATATCACGTATCAGAGTAACACTGCTTCTGCTGTTCTTGAAACAATTAC CAACATTCAACCCAAAGAGAGTGGAGGTGGTGTGGGAGAGACCCGGGAGGCTATTGTTTATAGATTATCTGAAGATATGCTGAGTAAACT CCCTCCTGATTACATTCCTCATGAGGTGAAATCTCGTTTGATAAAGATGGGCCATCTTAATTCAATGAACATATTTCTTAGACAAGAAAT TGACAGAATGCAAAGAGTCATTTCAATACTCCGCAGTAGCCTGAGTGATCTAAAATTGGCCATTGAAGGAACAATCATTATGAGTGAGAA TCTGAGAGATGCTCTGGACAACATGTATGATGCTCGTATACCTCAGCTCTGGAAAAGAGTGTCTTGGGATTCGTCCACACTGGGCTTCTG GTTCACTGAACTTTTGGAAAGAAATGCTCAGTTTTCTACGTGGATATTTGAAGGGAGGCCTAATGTGTTTTGGATGACTGGTTTCTTTAA TCCCCAAGGCTTCCTCACAGCAATGAGGCAAGAAGTGACCCGTGCCCACAAAGGCTGGGCACTGGACACTGTGACCATCCACAATGAAGT TCTGAGACAGACCAAGGAGGAGATCACGTCACCCCCTGGGGAAGGTGTGTATATTTATGGGCTCTACATGGATGGAGCAGCCTGGGACAG ACGGAATGGGAAGCTCATGGAATCCACCCCCAAGGTACTCTTCACGCAGTTACCCGTGCTCCACATCTTTGCCATTAACTCCACGGCACC CAAGGACCCCAAGCTGTATGTGTGTCCTATTTACAAGAAACCCAGGCGAACTGATTTGACCTTCATCACTGTGGTATATTTACGAACAGT |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_KCNK17_ENST00000453413_chr6_39271733_-_DNAH8_ENST00000449981_chr6_38889145_+_3245nt ATTCCCCAACACTCCTCCTCCCCGGCGAAACCGGGCACCAGCAGGCGTTTGCGAGAGGAGATACGAGCTGGACGCCTGGCCCTTCCCTCC CACCGGGTCCTAGTCCACCGCTCCCGGCGCCGGCTCCCCGCCTCTCCCGCTATGTACCGACCGCGAGCCCGGGCGGCTCCCGAGGGCAGG GTCCGGGGCTGCGCGGTGCCCAGCACCGTGCTCCTGCTGCTCGCCTACCTGGCTTACCTGGCGCTGGGCACCGGCGTGTTCTGGACGCTG GAGGGCCGCGCGGCGCAGGACTCCAGCCGCAGCTTCCAGCGCGACAAGTGGGAGCTGTTGCAGAACTTCACGTGTCTGGACCGCCCGGCG CTGGACTCGCTGATCCGGGATGTCGTCCAAGCATACAAAAACGGAGCCAGCCTCCTCAGCAACACCACCAGCATGGGGCGCTGGGAGCTC GTGGGCTCCTTCTTCTTTTCTGTGTCCACCATCACCACCATTGGCTATGGCAACCTGAGCCCCAACACGATGGCTGCCCGCCTCTTCTGC ATCTTCTTTGCCCTTGTGGGGATCCCACTCAACCTCGTGGTGCTCAACCGACTGGGGCATCTCATGCAGCAGGGAGTAAACCACTGGGCC AGCAGGCTGGGGGGCACCTGGCAGGATCCTGACAAGGCGCGGTGGCTGGCGGGCTCTGGCGCCCTCCTCTCGGGCCTCCTGCTCTTCCTG CTGCTGCCACCGCTGCTCTTCTCCCACATGGAGGGCTGGAGCTACACAGAGGGCTTCTACTTCGCCTTCATCACCCTCAGCACCGTGGGC TTCGGCGACTACGTGATTGGCCAACCTGGCCAAGCAGGAAGGCCGGTTAGCAGTTGCTAATGCTGAGTTAGGGAAGGCACAAGCCCTGCT GGATGAGAAGCAAGCTGAGCTGGATAAAGTACAGGCAAAATTTGATGCAGCAATGAATGAGAAAATGGATTTGCTTAATGACGCTGATAC GTGCCGGAAAAAGATGCAGGCCGCCTCCACTCTCATCGATGGGCTGAGTGGAGAAAAAATCCGGTGGACCCAGCAAAGTAAAGAATTCAA AGCTCAGATTAATAGACTTGTAGGTGATATTCTGCTGTGCACGGGATTCCTTTCCTACCTTGGTCCTTTCAATCAGATATTTAGGAACTA TTTGCTTAAAGATCAATGGGAAATGGAGTTGAGAGCACGGAAAATTCCTTTCACAGAAAACCTGAATCTTATTTCAATGTTGGTGGATCC TCCAACTATTGGTGAGTGGGGGCTACAGGGATTACCAGGAGATGATCTCTCAATTCAGAATGGCATTATTGTGACAAAGGCCACCAGATA CCCACTCCTCATAGACCCACAAACTCAAGGCAAAACTTGGATTAAATCAAAGGAAAAAGAAAATGATTTACAGGTGACATCTCTGAACCA TAAATATTTTCGCACACACTTGGAGGACAGCCTTTCCTTGGGCCGACCCCTTCTCATTGAGGACATTCATGAAGAGCTGGATCCAGCCTT GGATAATGTATTAGAAAAGAATTTTATTAAATCTGGCACCACTTTCAAGGTGAAAGTCGGTGATAAGGAATGTGATATCATGGATACATT TAAACTTTACATTACTACGAAGTTACCAAATCCTGCCTTTACCCCAGAGATTAATGCTAAAACGTCAGTCATTGATTTCACTGTTACAAT GAAAGGACTTGAGAATCAGTTACTAAGGAGAGTCATTCTAACAGAGAAACAGGAGTTAGAGGCTGAGAGGGTTAAACTTTTGGAGGATGT TACTTTTAATAAGCGGAAGATGAAAGAACTTGAAGATAACCTCCTCTATAAATTAAGTGCTACAAAAGGCTCATTGGTAGATGACGAATC TCTCATTGGTGTACTTCGAACTACCAAGCAGACAGCAGCTGAGGTAAGTGAAAAGTTGCATGTGGCTGCAGAAACTGAGATCAAGATCAA CGCGGCTCAGGAGGAGTTCCGGCCCGCAGCCACCCGCGGAAGCATCCTCTACTTCCTCATCACAGAGATGAGCATGGTCAACATCATGTA TCAGACGTCATTGGCCCAGTTCTTGAAGTTATTTGACCAGTCCATGGCCAGATCTGAAAAGTCACCACTACCTCAAAAGAGAATTACAAA TATTATCGAGTACCTGACATATGAAGTTTTTACATACTCTGTCAGAGGCCTATACGAAAACCACAAATTCCTGTTTGTACTCCTCATGAC CTTAAAGATTGACCTTCAGAGAGGGACAGTTAAGCACAGAGAGTTTCAAGCTCTCATTAAAGGGGGAGCAGCTCTGGACCTGAAAGCCTG TCCTCCCAAACCCTATCGCTGGATCCTTGACATGACTTGGCTGAATCTTGTGGAGCTGAGTAAACTTCCACAATTTGCAGAAATTATGAA CCAGATATCTCGTAATGAGAAGGGGTGGAAAAGCTGGTTTGATAAAGATGCTCCAGAGGAGGAAATTATCCCTGATGGATATAATGATTC ACTAGATACCTGCCATAAACTTTTACTTATCAGGTCTTGGTGCCCAGACCGTACTGTTTTTCAAGCAAGAAAGTATATTGCAGATTCTTT GGAGGAGAAGTACACAGAACCAGTTATCTTAAATCTGGAGAAAACTTGGGAAGAAAGTGATACCCGGACACCTCTGATATGCTTCCTGTC CATGGGATCTGACCCCACCAATCAAATTGATGCATTGGCCAAGAAACTGAAACTGGAATGTAGAACTATCTCAATGGGGCAAGGACAAGA AGTACATGCTCGAAAGCTGATTCAGATGTCAATGCAGCAGGTATGTGACAAGAGACTGCTCCTGCTGCAACATTATTGCTAGAAACCCCA CAATCATGGATGTTACCACATTCTTCTCGTGATGCTCAATCCTGGTTTTTCCATTTTTGTTTATCATTACCTGTGAATTTTAAACCTCAG TCTAGTTTCCTCCTGATATTCGCATGGAAAGCTTATTCCATTTTCTATAGTATATGCTCCATTTTACCTTCACCAATTTTTTGTTCGTTT TATGATTTGGGAGACACACCTTCTGATTTCTAAGAATGCATCTCTAGCAGTCTTGGAATTTCATGATCAATATGAATAGGTAGTACTTAA GGAGTGACAGATTGAGACAGTTAAATTTCCATTTTCAGTTAAAGGCAGACTTTCATTTTTCATTAACGGATCATTTCAGGCAAAGAAGGA >In-frame_KCNK17_ENST00000453413_chr6_39271733_-_DNAH8_ENST00000359357_chr6_38889145_+_4562nt ATTCCCCAACACTCCTCCTCCCCGGCGAAACCGGGCACCAGCAGGCGTTTGCGAGAGGAGATACGAGCTGGACGCCTGGCCCTTCCCTCC CACCGGGTCCTAGTCCACCGCTCCCGGCGCCGGCTCCCCGCCTCTCCCGCTATGTACCGACCGCGAGCCCGGGCGGCTCCCGAGGGCAGG GTCCGGGGCTGCGCGGTGCCCAGCACCGTGCTCCTGCTGCTCGCCTACCTGGCTTACCTGGCGCTGGGCACCGGCGTGTTCTGGACGCTG GAGGGCCGCGCGGCGCAGGACTCCAGCCGCAGCTTCCAGCGCGACAAGTGGGAGCTGTTGCAGAACTTCACGTGTCTGGACCGCCCGGCG CTGGACTCGCTGATCCGGGATGTCGTCCAAGCATACAAAAACGGAGCCAGCCTCCTCAGCAACACCACCAGCATGGGGCGCTGGGAGCTC GTGGGCTCCTTCTTCTTTTCTGTGTCCACCATCACCACCATTGGCTATGGCAACCTGAGCCCCAACACGATGGCTGCCCGCCTCTTCTGC ATCTTCTTTGCCCTTGTGGGGATCCCACTCAACCTCGTGGTGCTCAACCGACTGGGGCATCTCATGCAGCAGGGAGTAAACCACTGGGCC AGCAGGCTGGGGGGCACCTGGCAGGATCCTGACAAGGCGCGGTGGCTGGCGGGCTCTGGCGCCCTCCTCTCGGGCCTCCTGCTCTTCCTG CTGCTGCCACCGCTGCTCTTCTCCCACATGGAGGGCTGGAGCTACACAGAGGGCTTCTACTTCGCCTTCATCACCCTCAGCACCGTGGGC TTCGGCGACTACGTGATTGGCCAACCTGGCCAAGCAGGAAGGCCGGTTAGCAGTTGCTAATGCTGAGTTAGGGAAGGCACAAGCCCTGCT GGATGAGAAGCAAGCTGAGCTGGATAAAGTACAGGCAAAATTTGATGCAGCAATGAATGAGAAAATGGATTTGCTTAATGACGCTGATAC GTGCCGGAAAAAGATGCAGGCCGCCTCCACTCTCATCGATGGGCTGAGTGGAGAAAAAATCCGGTGGACCCAGCAAAGTAAAGAATTCAA AGCTCAGATTAATAGACTTGTAGGTGATATTCTGCTGTGCACGGGATTCCTTTCCTACCTTGGTCCTTTCAATCAGATATTTAGGAACTA TTTGCTTAAAGATCAATGGGAAATGGAGTTGAGAGCACGGAAAATTCCTTTCACAGAAAACCTGAATCTTATTTCAATGTTGGTGGATCC TCCAACTATTGGTGAGTGGGGGCTACAGGGATTACCAGGAGATGATCTCTCAATTCAGAATGGCATTATTGTGACAAAGGCCACCAGATA CCCACTCCTCATAGACCCACAAACTCAAGGCAAAACTTGGATTAAATCAAAGGAAAAAGAAAATGATTTACAGGTGACATCTCTGAACCA TAAATATTTTCGCACACACTTGGAGGACAGCCTTTCCTTGGGCCGACCCCTTCTCATTGAGGACATTCATGAAGAGCTGGATCCAGCCTT GGATAATGTATTAGAAAAGAATTTTATTAAATCTGGCACCACTTTCAAGGTGAAAGTCGGTGATAAGGAATGTGATATCATGGATACATT TAAACTTTACATTACTACGAAGTTACCAAATCCTGCCTTTACCCCAGAGATTAATGCTAAAACGTCAGTCATTGATTTCACTGTTACAAT GAAAGGACTTGAGAATCAGTTACTAAGGAGAGTCATTCTAACAGAGAAACAGGAGTTAGAGGCTGAGAGGGTTAAACTTTTGGAGGATGT TACTTTTAATAAGCGGAAGATGAAAGAACTTGAAGATAACCTCCTCTATAAATTAAGTGCTACAAAAGGCTCATTGGTAGATGACGAATC TCTCATTGGTGTACTTCGAACTACCAAGCAGACAGCAGCTGAGGTAAGTGAAAAGTTGCATGTGGCTGCAGAAACTGAGATCAAGATCAA CGCGGCTCAGGAGGAGTTCCGGCCCGCAGCCACCCGCGGAAGCATCCTCTACTTCCTCATCACAGAGATGAGCATGGTCAACATCATGTA TCAGACGTCATTGGCCCAGTTCTTGAAGTTATTTGACCAGTCCATGGCCAGATCTGAAAAGTCACCACTACCTCAAAAGAGAATTACAAA TATTATCGAGTACCTGACATATGAAGTTTTTACATACTCTGTCAGAGGCCTATACGAAAACCACAAATTCCTGTTTGTACTCCTCATGAC CTTAAAGATTGACCTTCAGAGAGGGACAGTTAAGCACAGAGAGTTTCAAGCTCTCATTAAAGGGGGAGCAGCTCTGGACCTGAAAGCCTG TCCTCCCAAACCCTATCGCTGGATCCTTGACATGACTTGGCTGAATCTTGTGGAGCTGAGTAAACTTCCACAATTTGCAGAAATTATGAA CCAGATATCTCGTAATGAGAAGGGGTGGAAAAGCTGGTTTGATAAAGATGCTCCAGAGGAGGAAATTATCCCTGATGGATATAATGATTC ACTAGATACCTGCCATAAACTTTTACTTATCAGGTCTTGGTGCCCAGACCGTACTGTTTTTCAAGCAAGAAAGTATATTGCAGATTCTTT GGAGGAGAAGTACACAGAACCAGTTATCTTAAATCTGGAGAAAACTTGGGAAGAAAGTGATACCCGGACACCTCTGATATGCTTCCTGTC CATGGGATCTGACCCCACCAATCAAATTGATGCATTGGCCAAGAAACTGAAACTGGAATGTAGAACTATCTCAATGGGGCAAGGACAAGA AGTACATGCTCGAAAGCTGATTCAGATGTCAATGCAGCAGGGTGGTTGGGTATTACTACAAAATTGCCACCTTGGCCTGGAATTCATGGA AGAATTACTAGAGACGCTAATTACCACTGAAGCCAGTGATGATTCTTTCCGAGTATGGATAACTACGGAGCCCCATGATCGATTTCCAAT TACATTGCTTCAGACCTCTCTCAAATTCACTAATGAGCCACCCCAAGGTGTACGCGCAGGTTTGAAAAGAACATTTGCTGGAATTAATCA AGACCTTCTGGACATCAGTAATTTACCCATGTGGAAGCCGATGCTTTACACAGTAGCATTTTTACACTCCACTGTGCAGGAGCGACGAAA ATTTGGCCCCTTAGGATGGAATATTCCCTACGAATTCAATTCTGCTGACTTTTCAGCCAGTGTTCAGTTTATTCAGAATCACCTTGATGA ATGCGATATTAAGAAAGGTGTATCATGGAATACGGTTCGGTACATGATCGGAGAAGTACAATATGGAGGCAGAGTGACAGATGACTTTGA CAAACGTCTACTTAATTGCTTTGCCAGAGTCTGGTTCAGTGAGAAGATGTTTGAACCGTCATTCTGCTTTTATACTGGATATAAAATCCC CTTATGCAAAACCTTAGACCAGTATTTTGAATACATCCAGTCACTGCCATCCCTAGATAACCCTGAAGTCTTTGGGCTTCACCCTAATGC TGATATCACGTATCAGAGTAACACTGCTTCTGCTGTTCTTGAAACAATTACCAACATTCAACCCAAAGAGAGTGGAGGTGGTGTGGGAGA GACCCGGGAGGCTATTGTTTATAGATTATCTGAAGATATGCTGAGTAAACTCCCTCCTGATTACATTCCTCATGAGGTGAAATCTCGTTT GATAAAGATGGGCCATCTTAATTCAATGAACATATTTCTTAGACAAGAAATTGACAGAATGCAAAGAGTCATTTCAATACTCCGCAGTAG CCTGAGTGATCTAAAATTGGCCATTGAAGGAACAATCATTATGAGTGAGAATCTGAGAGATGCTCTGGACAACATGTATGATGCTCGTAT ACCTCAGCTCTGGAAAAGAGTGTCTTGGGATTCGTCCACACTGGGCTTCTGGTTCACTGAACTTTTGGAAAGAAATGCTCAGTTTTCTAC GTGGATATTTGAAGGGAGGCCTAATGTGTTTTGGATGACTGGTTTCTTTAATCCCCAAGGCTTCCTCACAGCAATGAGGCAAGAAGTGAC CCGTGCCCACAAAGGCTGGGCACTGGACACTGTGACCATCCACAATGAAGTTCTGAGACAGACCAAGGAGGAGATCACGTCACCCCCTGG GGAAGGTGTGTATATTTATGGGCTCTACATGGATGGAGCAGCCTGGGACAGACGGAATGGGAAGCTCATGGAATCCACCCCCAAGGTACT CTTCACGCAGTTACCCGTGCTCCACATCTTTGCCATTAACTCCACGGCACCCAAGGACCCCAAGCTGTATGTGTGTCCTATTTACAAGAA ACCCAGGCGAACTGATTTGACCTTCATCACTGTGGTATATTTACGAACAGTGTTGTCCCCGGATCACTGGATCCTGAGAGGAGTGGCCCT TTTGTGTGACATCAAGTAAGTTCATTTCCATCTGCTCAGGGCACCAGAACCCACATAGACAGCCTGTGCTATTGAGGGACTCAGTGATGT >In-frame_KCNK17_ENST00000453413_chr6_39271733_-_DNAH8_ENST00000441566_chr6_38889145_+_4429nt ATTCCCCAACACTCCTCCTCCCCGGCGAAACCGGGCACCAGCAGGCGTTTGCGAGAGGAGATACGAGCTGGACGCCTGGCCCTTCCCTCC CACCGGGTCCTAGTCCACCGCTCCCGGCGCCGGCTCCCCGCCTCTCCCGCTATGTACCGACCGCGAGCCCGGGCGGCTCCCGAGGGCAGG GTCCGGGGCTGCGCGGTGCCCAGCACCGTGCTCCTGCTGCTCGCCTACCTGGCTTACCTGGCGCTGGGCACCGGCGTGTTCTGGACGCTG GAGGGCCGCGCGGCGCAGGACTCCAGCCGCAGCTTCCAGCGCGACAAGTGGGAGCTGTTGCAGAACTTCACGTGTCTGGACCGCCCGGCG CTGGACTCGCTGATCCGGGATGTCGTCCAAGCATACAAAAACGGAGCCAGCCTCCTCAGCAACACCACCAGCATGGGGCGCTGGGAGCTC GTGGGCTCCTTCTTCTTTTCTGTGTCCACCATCACCACCATTGGCTATGGCAACCTGAGCCCCAACACGATGGCTGCCCGCCTCTTCTGC ATCTTCTTTGCCCTTGTGGGGATCCCACTCAACCTCGTGGTGCTCAACCGACTGGGGCATCTCATGCAGCAGGGAGTAAACCACTGGGCC AGCAGGCTGGGGGGCACCTGGCAGGATCCTGACAAGGCGCGGTGGCTGGCGGGCTCTGGCGCCCTCCTCTCGGGCCTCCTGCTCTTCCTG CTGCTGCCACCGCTGCTCTTCTCCCACATGGAGGGCTGGAGCTACACAGAGGGCTTCTACTTCGCCTTCATCACCCTCAGCACCGTGGGC TTCGGCGACTACGTGATTGGCCAACCTGGCCAAGCAGGAAGGCCGGTTAGCAGTTGCTAATGCTGAGTTAGGGAAGGCACAAGCCCTGCT GGATGAGAAGCAAGCTGAGCTGGATAAAGTACAGGCAAAATTTGATGCAGCAATGAATGAGAAAATGGATTTGCTTAATGACGCTGATAC GTGCCGGAAAAAGATGCAGGCCGCCTCCACTCTCATCGATGGGCTGAGTGGAGAAAAAATCCGGTGGACCCAGCAAAGTAAAGAATTCAA AGCTCAGATTAATAGACTTGTAGGTGATATTCTGCTGTGCACGGGATTCCTTTCCTACCTTGGTCCTTTCAATCAGATATTTAGGAACTA TTTGCTTAAAGATCAATGGGAAATGGAGTTGAGAGCACGGAAAATTCCTTTCACAGAAAACCTGAATCTTATTTCAATGTTGGTGGATCC TCCAACTATTGGTGAGTGGGGGCTACAGGGATTACCAGGAGATGATCTCTCAATTCAGAATGGCATTATTGTGACAAAGGCCACCAGATA CCCACTCCTCATAGACCCACAAACTCAAGGCAAAACTTGGATTAAATCAAAGGAAAAAGAAAATGATTTACAGGTGACATCTCTGAACCA TAAATATTTTCGCACACACTTGGAGGACAGCCTTTCCTTGGGCCGACCCCTTCTCATTGAGGACATTCATGAAGAGCTGGATCCAGCCTT GGATAATGTATTAGAAAAGAATTTTATTAAATCTGGCACCACTTTCAAGGTGAAAGTCGGTGATAAGGAATGTGATATCATGGATACATT TAAACTTTACATTACTACGAAGTTACCAAATCCTGCCTTTACCCCAGAGATTAATGCTAAAACGTCAGTCATTGATTTCACTGTTACAAT GAAAGGACTTGAGAATCAGTTACTAAGGAGAGTCATTCTAACAGAGAAACAGGAGTTAGAGGCTGAGAGGGTTAAACTTTTGGAGGATGT TACTTTTAATAAGCGGAAGATGAAAGAACTTGAAGATAACCTCCTCTATAAATTAAGTGCTACAAAAGGCTCATTGGTAGATGACGAATC TCTCATTGGTGTACTTCGAACTACCAAGCAGACAGCAGCTGAGGTAAGTGAAAAGTTGCATGTGGCTGCAGAAACTGAGATCAAGATCAA CGCGGCTCAGGAGGAGTTCCGGCCCGCAGCCACCCGCGGAAGCATCCTCTACTTCCTCATCACAGAGATGAGCATGGTCAACATCATGTA TCAGACGTCATTGGCCCAGTTCTTGAAGTTATTTGACCAGTCCATGGCCAGATCTGAAAAGTCACCACTACCTCAAAAGAGAATTACAAA TATTATCGAGTACCTGACATATGAAGTTTTTACATACTCTGTCAGAGGCCTATACGAAAACCACAAATTCCTGTTTGTACTCCTCATGAC CTTAAAGATTGACCTTCAGAGAGGGACAGTTAAGCACAGAGAGTTTCAAGCTCTCATTAAAGGGGGAGCAGCTCTGGACCTGAAAGCCTG TCCTCCCAAACCCTATCGCTGGATCCTTGACATGACTTGGCTGAATCTTGTGGAGCTGAGTAAACTTCCACAATTTGCAGAAATTATGAA CCAGATATCTCGTAATGAGAAGGGGTGGAAAAGCTGGTTTGATAAAGATGCTCCAGAGGAGGAAATTATCCCTGATGGATATAATGATTC ACTAGATACCTGCCATAAACTTTTACTTATCAGGTCTTGGTGCCCAGACCGTACTGTTTTTCAAGCAAGAAAGTATATTGCAGATTCTTT GGAGGAGAAGTACACAGAACCAGTTATCTTAAATCTGGAGAAAACTTGGGAAGAAAGTGATACCCGGACACCTCTGATATGCTTCCTGTC CATGGGATCTGACCCCACCAATCAAATTGATGCATTGGCCAAGAAACTGAAACTGGAATGTAGAACTATCTCAATGGGGCAAGGACAAGA AGTACATGCTCGAAAGCTGATTCAGATGTCAATGCAGCAGGGTGGTTGGGTATTACTACAAAATTGCCACCTTGGCCTGGAATTCATGGA AGAATTACTAGAGACGCTAATTACCACTGAAGCCAGTGATGATTCTTTCCGAGTATGGATAACTACGGAGCCCCATGATCGATTTCCAAT TACATTGCTTCAGACCTCTCTCAAATTCACTAATGAGCCACCCCAAGGTGTACGCGCAGGTTTGAAAAGAACATTTGCTGGAATTAATCA AGACCTTCTGGACATCAGTAATTTACCCATGTGGAAGCCGATGCTTTACACAGTAGCATTTTTACACTCCACTGTGCAGGAGCGACGAAA ATTTGGCCCCTTAGGATGGAATATTCCCTACGAATTCAATTCTGCTGACTTTTCAGCCAGTGTTCAGTTTATTCAGAATCACCTTGATGA ATGCGATATTAAGAAAGGTGTATCATGGAATACGGTTCGGTACATGATCGGAGAAGTACAATATGGAGGCAGAGTGACAGATGACTTTGA CAAACGTCTACTTAATTGCTTTGCCAGAGTCTGGTTCAGTGAGAAGATGTTTGAACCGTCATTCTGCTTTTATACTGGATATAAAATCCC CTTATGCAAAACCTTAGACCAGTATTTTGAATACATCCAGTCACTGCCATCCCTAGATAACCCTGAAGTCTTTGGGCTTCACCCTAATGC TGATATCACGTATCAGAGTAACACTGCTTCTGCTGTTCTTGAAACAATTACCAACATTCAACCCAAAGAGAGTGGAGGTGGTGTGGGAGA GACCCGGGAGGCTATTGTTTATAGATTATCTGAAGATATGCTGAGTAAACTCCCTCCTGATTACATTCCTCATGAGGTGAAATCTCGTTT GATAAAGATGGGCCATCTTAATTCAATGAACATATTTCTTAGACAAGAAATTGACAGAATGCAAAGAGTCATTTCAATACTCCGCAGTAG CCTGAGTGATCTAAAATTGGCCATTGAAGGAACAATCATTATGAGTGAGAATCTGAGAGATGCTCTGGACAACATGTATGATGCTCGTAT ACCTCAGCTCTGGAAAAGAGTGTCTTGGGATTCGTCCACACTGGGCTTCTGGTTCACTGAACTTTTGGAAAGAAATGCTCAGTTTTCTAC GTGGATATTTGAAGGGAGGCCTAATGTGTTTTGGATGACTGGTTTCTTTAATCCCCAAGGCTTCCTCACAGCAATGAGGCAAGAAGTGAC CCGTGCCCACAAAGGCTGGGCACTGGACACTGTGACCATCCACAATGAAGTTCTGAGACAGACCAAGGAGGAGATCACGTCACCCCCTGG GGAAGGTGTGTATATTTATGGGCTCTACATGGATGGAGCAGCCTGGGACAGACGGAATGGGAAGCTCATGGAATCCACCCCCAAGGTACT CTTCACGCAGTTACCCGTGCTCCACATCTTTGCCATTAACTCCACGGCACCCAAGGACCCCAAGCTGTATGTGTGTCCTATTTACAAGAA ACCCAGGCGAACTGATTTGACCTTCATCACTGTGGTATATTTACGAACAGTGTTGTCCCCGGATCACTGGATCCTGAGAGGAGTGGCCCT |
Top |
FusionGenePPI for KCNK17_DNAH8 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| KCNK17 | VKORC1 | DNAH8 | GAN, EGFR |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
Top |
RelatedDrugs for KCNK17_DNAH8 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
Top |
RelatedDiseases for KCNK17_DNAH8 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Tgene | DNAH8 | C0005586 | Bipolar Disorder | 4 | PSYGENET |
| Tgene | DNAH8 | C0338831 | Manic | 2 | PSYGENET |
| Tgene | DNAH8 | C0236736 | Cocaine-Related Disorders | 1 | CTD_human |
| Tgene | DNAH8 | C0236969 | Substance-Related Disorders | 1 | CTD_human |
| Tgene | DNAH8 | C1456784 | Paranoia | 1 | CTD_human |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
|