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Fusion gene ID: 18226 |
FusionGeneSummary for KBTBD6_TEX29 |
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Fusion gene information | Fusion gene name: KBTBD6_TEX29 | Fusion gene ID: 18226 | Hgene | Tgene | Gene symbol | KBTBD6 | TEX29 | Gene ID | 89890 | 121793 |
Gene name | kelch repeat and BTB domain containing 6 | testis expressed 29 | |
Synonyms | - | C13orf16|bA474D23.1 | |
Cytomap | 13q14.11 | 13q34 | |
Type of gene | protein-coding | protein-coding | |
Description | kelch repeat and BTB domain-containing protein 6kelch repeat and BTB (POZ) domain containing 6 | testis-expressed protein 29testis-expressed sequence 29 protein | |
Modification date | 20180522 | 20180519 | |
UniProtAcc | Q86V97 | Q8N6K0 | |
Ensembl transtripts involved in fusion gene | ENST00000379485, ENST00000499385, | ENST00000283547, | |
Fusion gene scores | * DoF score | 1 X 1 X 1=1 | 1 X 1 X 1=1 |
# samples | 1 | 1 | |
** MAII score | log2(1/1*10)=3.32192809488736 | log2(1/1*10)=3.32192809488736 | |
Context | PubMed: KBTBD6 [Title/Abstract] AND TEX29 [Title/Abstract] AND fusion [Title/Abstract] | ||
Functional or gene categories assigned by FusionGDB annotation |
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
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Partner | Gene | GO ID | GO term | PubMed ID |
![]() (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
TCGA | LD | BLCA | TCGA-UY-A78N-01A | KBTBD6 | chr13 | 41706838 | - | TEX29 | chr13 | 111968532 | + |
* LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
![]() * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
intron-intron | ENST00000379485 | ENST00000283547 | KBTBD6 | chr13 | 41706838 | - | TEX29 | chr13 | 111968532 | + |
intron-intron | ENST00000499385 | ENST00000283547 | KBTBD6 | chr13 | 41706838 | - | TEX29 | chr13 | 111968532 | + |
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FusionProtFeatures for KBTBD6_TEX29 |
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Hgene | Tgene |
KBTBD6 | TEX29 |
![]() * Minus value of BPloci means that the break pointn is located before the CDS. |
- In-frame and retained protein feature among the 13 regional features. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
- In-frame and not-retained protein feature among the 13 regional features. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
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FusionGeneSequence for KBTBD6_TEX29 |
![]() (nt: nucleotides, aa: amino acids) |
* Fusion amino acid sequences. |
* Fusion transcript sequences (only coding sequence (CDS) region). |
* Fusion transcript sequences (Full-length transcript). |
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FusionGenePPI for KBTBD6_TEX29 |
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Hgene | Hgene's interactors | Tgene | Tgene's interactors |
KBTBD6 | OSBPL9, GABARAPL1, KBTBD7, CUL3, COPS5, DCUN1D1, NEDD8, KLHL29, NUDCD3, AZU1, TRMT10B, DOK4, FOXS1, DEF6, PARD6B, ZSCAN26, FOSL2, LUC7L, ZNF562, AP2M1, PCMT1, ZFP41, RBX1, TIAM1, MAP1LC3B, GABARAP, GABARAPL2, MAP1LC3C, HIST1H2BG, CEP128, CDX1, CLEC3A, UBE2M, PPP1R21, RBFA, LLGL2, ARIH1, LMO2, TXNIP, ZNF574, RPS19BP1, MEAF6, ALX3 | TEX29 | NDFIP1, FLVCR1, HIP1R, TOR1A, LEMD3, SLC4A7, FAM207A, PLAA, SLC6A15, PTS, STEAP3, GOLGA5, SLC16A2, ZDHHC9, STX10, PAM16, PTRH2, TMX4 |
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Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
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Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for KBTBD6_TEX29 |
![]() (DrugBank Version 5.1.0 2018-04-02) |
Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for KBTBD6_TEX29 |
![]() (DisGeNet 4.0) |
Partner | Gene | Disease ID | Disease name | # pubmeds | Source |