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Fusion gene ID: 17885 |
FusionGeneSummary for ITGB5_PDLIM5 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: ITGB5_PDLIM5 | Fusion gene ID: 17885 | Hgene | Tgene | Gene symbol | ITGB5 | PDLIM5 | Gene ID | 3693 | 10611 |
| Gene name | integrin subunit beta 5 | PDZ and LIM domain 5 | |
| Synonyms | - | ENH|ENH1|L9|LIM | |
| Cytomap | 3q21.2 | 4q22.3 | |
| Type of gene | protein-coding | protein-coding | |
| Description | integrin beta-5testis secretory sperm-binding protein Li 217p | PDZ and LIM domain protein 5enigma homologenigma-like LIM domain proteinenigma-like PDZ and LIM domains protein | |
| Modification date | 20180523 | 20180522 | |
| UniProtAcc | P18084 | Q96HC4 | |
| Ensembl transtripts involved in fusion gene | ENST00000296181, ENST00000461306, | ENST00000450793, ENST00000538141, ENST00000380180, ENST00000318007, ENST00000437932, ENST00000317968, ENST00000542407, ENST00000508216, ENST00000514743, ENST00000380176, ENST00000359265, ENST00000512274, ENST00000504489, | |
| Fusion gene scores | * DoF score | 8 X 8 X 6=384 | 9 X 12 X 5=540 |
| # samples | 9 | 12 | |
| ** MAII score | log2(9/384*10)=-2.09310940439148 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(12/540*10)=-2.16992500144231 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: ITGB5 [Title/Abstract] AND PDLIM5 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | OV | TCGA-24-1843-01A | ITGB5 | chr3 | 124578089 | - | PDLIM5 | chr4 | 95507559 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000296181 | ENST00000450793 | ITGB5 | chr3 | 124578089 | - | PDLIM5 | chr4 | 95507559 | + |
| In-frame | ENST00000296181 | ENST00000538141 | ITGB5 | chr3 | 124578089 | - | PDLIM5 | chr4 | 95507559 | + |
| In-frame | ENST00000296181 | ENST00000380180 | ITGB5 | chr3 | 124578089 | - | PDLIM5 | chr4 | 95507559 | + |
| In-frame | ENST00000296181 | ENST00000318007 | ITGB5 | chr3 | 124578089 | - | PDLIM5 | chr4 | 95507559 | + |
| In-frame | ENST00000296181 | ENST00000437932 | ITGB5 | chr3 | 124578089 | - | PDLIM5 | chr4 | 95507559 | + |
| In-frame | ENST00000296181 | ENST00000317968 | ITGB5 | chr3 | 124578089 | - | PDLIM5 | chr4 | 95507559 | + |
| In-frame | ENST00000296181 | ENST00000542407 | ITGB5 | chr3 | 124578089 | - | PDLIM5 | chr4 | 95507559 | + |
| In-frame | ENST00000296181 | ENST00000508216 | ITGB5 | chr3 | 124578089 | - | PDLIM5 | chr4 | 95507559 | + |
| In-frame | ENST00000296181 | ENST00000514743 | ITGB5 | chr3 | 124578089 | - | PDLIM5 | chr4 | 95507559 | + |
| 5CDS-3UTR | ENST00000296181 | ENST00000380176 | ITGB5 | chr3 | 124578089 | - | PDLIM5 | chr4 | 95507559 | + |
| 5CDS-intron | ENST00000296181 | ENST00000359265 | ITGB5 | chr3 | 124578089 | - | PDLIM5 | chr4 | 95507559 | + |
| 5CDS-intron | ENST00000296181 | ENST00000512274 | ITGB5 | chr3 | 124578089 | - | PDLIM5 | chr4 | 95507559 | + |
| 5CDS-intron | ENST00000296181 | ENST00000504489 | ITGB5 | chr3 | 124578089 | - | PDLIM5 | chr4 | 95507559 | + |
| intron-3CDS | ENST00000461306 | ENST00000450793 | ITGB5 | chr3 | 124578089 | - | PDLIM5 | chr4 | 95507559 | + |
| intron-3CDS | ENST00000461306 | ENST00000538141 | ITGB5 | chr3 | 124578089 | - | PDLIM5 | chr4 | 95507559 | + |
| intron-3CDS | ENST00000461306 | ENST00000380180 | ITGB5 | chr3 | 124578089 | - | PDLIM5 | chr4 | 95507559 | + |
| intron-3CDS | ENST00000461306 | ENST00000318007 | ITGB5 | chr3 | 124578089 | - | PDLIM5 | chr4 | 95507559 | + |
| intron-3CDS | ENST00000461306 | ENST00000437932 | ITGB5 | chr3 | 124578089 | - | PDLIM5 | chr4 | 95507559 | + |
| intron-3CDS | ENST00000461306 | ENST00000317968 | ITGB5 | chr3 | 124578089 | - | PDLIM5 | chr4 | 95507559 | + |
| intron-3CDS | ENST00000461306 | ENST00000542407 | ITGB5 | chr3 | 124578089 | - | PDLIM5 | chr4 | 95507559 | + |
| intron-3CDS | ENST00000461306 | ENST00000508216 | ITGB5 | chr3 | 124578089 | - | PDLIM5 | chr4 | 95507559 | + |
| intron-3CDS | ENST00000461306 | ENST00000514743 | ITGB5 | chr3 | 124578089 | - | PDLIM5 | chr4 | 95507559 | + |
| intron-3UTR | ENST00000461306 | ENST00000380176 | ITGB5 | chr3 | 124578089 | - | PDLIM5 | chr4 | 95507559 | + |
| intron-intron | ENST00000461306 | ENST00000359265 | ITGB5 | chr3 | 124578089 | - | PDLIM5 | chr4 | 95507559 | + |
| intron-intron | ENST00000461306 | ENST00000512274 | ITGB5 | chr3 | 124578089 | - | PDLIM5 | chr4 | 95507559 | + |
| intron-intron | ENST00000461306 | ENST00000504489 | ITGB5 | chr3 | 124578089 | - | PDLIM5 | chr4 | 95507559 | + |
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FusionProtFeatures for ITGB5_PDLIM5 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| ITGB5 | PDLIM5 |
| Integrin alpha-V/beta-5 (ITGAV:ITGB5) is a receptor forfibronectin. It recognizes the sequence R-G-D in its ligand. (Microbial infection) Integrin ITGAV:ITGB5 acts as areceptor for adenovirus type C. {ECO:0000269|PubMed:20615244}. | May play an important role in the heart development byscaffolding PKC to the Z-disk region. May play a role in theregulation of cardiomyocyte expansion. Overexpression promotes thedevelopment of heart hypertrophy. Contributes to the regulation ofdendritic spine morphogenesis in neurons. May restrainpostsynaptic growth of excitatory synapses (By similarity).{ECO:0000250}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | ITGB5 | chr3:124578089 | chr4:95507559 | ENST00000296181 | - | 3 | 15 | 27_76 | 120 | 800 | Domain | Note=PSI |
| Tgene | >PDLIM5 | chr3:124578089 | chr4:95507559 | ENST00000317968 | + | 5 | 13 | 418_477 | 294 | 597 | Domain | LIM zinc-binding 1 |
| Tgene | >PDLIM5 | chr3:124578089 | chr4:95507559 | ENST00000317968 | + | 5 | 13 | 477_536 | 294 | 597 | Domain | LIM zinc-binding 2 |
| Tgene | >PDLIM5 | chr3:124578089 | chr4:95507559 | ENST00000317968 | + | 5 | 13 | 536_596 | 294 | 597 | Domain | LIM zinc-binding 3 |
| Tgene | >PDLIM5 | chr3:124578089 | chr4:95507559 | ENST00000318007 | + | 7 | 10 | 418_477 | 171 | 215 | Domain | LIM zinc-binding 1 |
| Tgene | >PDLIM5 | chr3:124578089 | chr4:95507559 | ENST00000318007 | + | 7 | 10 | 477_536 | 171 | 215 | Domain | LIM zinc-binding 2 |
| Tgene | >PDLIM5 | chr3:124578089 | chr4:95507559 | ENST00000318007 | + | 7 | 10 | 536_596 | 171 | 215 | Domain | LIM zinc-binding 3 |
| Tgene | >PDLIM5 | chr3:124578089 | chr4:95507559 | ENST00000359265 | + | 0 | 3 | 2_85 | -51 | 137 | Domain | PDZ |
| Tgene | >PDLIM5 | chr3:124578089 | chr4:95507559 | ENST00000359265 | + | 0 | 3 | 418_477 | -51 | 137 | Domain | LIM zinc-binding 1 |
| Tgene | >PDLIM5 | chr3:124578089 | chr4:95507559 | ENST00000359265 | + | 0 | 3 | 477_536 | -51 | 137 | Domain | LIM zinc-binding 2 |
| Tgene | >PDLIM5 | chr3:124578089 | chr4:95507559 | ENST00000359265 | + | 0 | 3 | 536_596 | -51 | 137 | Domain | LIM zinc-binding 3 |
| Tgene | >PDLIM5 | chr3:124578089 | chr4:95507559 | ENST00000380180 | + | 6 | 9 | 418_477 | 191 | 235 | Domain | LIM zinc-binding 1 |
| Tgene | >PDLIM5 | chr3:124578089 | chr4:95507559 | ENST00000380180 | + | 6 | 9 | 477_536 | 191 | 235 | Domain | LIM zinc-binding 2 |
| Tgene | >PDLIM5 | chr3:124578089 | chr4:95507559 | ENST00000380180 | + | 6 | 9 | 536_596 | 191 | 235 | Domain | LIM zinc-binding 3 |
| Tgene | >PDLIM5 | chr3:124578089 | chr4:95507559 | ENST00000437932 | + | 5 | 13 | 418_477 | 185 | 488 | Domain | LIM zinc-binding 1 |
| Tgene | >PDLIM5 | chr3:124578089 | chr4:95507559 | ENST00000437932 | + | 5 | 13 | 477_536 | 185 | 488 | Domain | LIM zinc-binding 2 |
| Tgene | >PDLIM5 | chr3:124578089 | chr4:95507559 | ENST00000437932 | + | 5 | 13 | 536_596 | 185 | 488 | Domain | LIM zinc-binding 3 |
| Tgene | >PDLIM5 | chr3:124578089 | chr4:95507559 | ENST00000508216 | + | 5 | 8 | 418_477 | 191 | 235 | Domain | LIM zinc-binding 1 |
| Tgene | >PDLIM5 | chr3:124578089 | chr4:95507559 | ENST00000508216 | + | 5 | 8 | 477_536 | 191 | 235 | Domain | LIM zinc-binding 2 |
| Tgene | >PDLIM5 | chr3:124578089 | chr4:95507559 | ENST00000508216 | + | 5 | 8 | 536_596 | 191 | 235 | Domain | LIM zinc-binding 3 |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >ITGB5 | chr3:124578089 | chr4:95507559 | ENST00000296181 | - | 3 | 15 | 136_378 | 120 | 800 | Domain | Note=VWFA |
| Hgene | >ITGB5 | chr3:124578089 | chr4:95507559 | ENST00000296181 | - | 3 | 15 | 465_630 | 120 | 800 | Region | Note=Cysteine-rich tandem repeats |
| Hgene | >ITGB5 | chr3:124578089 | chr4:95507559 | ENST00000296181 | - | 3 | 15 | 465_512 | 120 | 800 | Repeat | Note=I |
| Hgene | >ITGB5 | chr3:124578089 | chr4:95507559 | ENST00000296181 | - | 3 | 15 | 513_554 | 120 | 800 | Repeat | Note=II |
| Hgene | >ITGB5 | chr3:124578089 | chr4:95507559 | ENST00000296181 | - | 3 | 15 | 555_593 | 120 | 800 | Repeat | Note=III |
| Hgene | >ITGB5 | chr3:124578089 | chr4:95507559 | ENST00000296181 | - | 3 | 15 | 594_630 | 120 | 800 | Repeat | Note=IV |
| Hgene | >ITGB5 | chr3:124578089 | chr4:95507559 | ENST00000296181 | - | 3 | 15 | 24_719 | 120 | 800 | Topological domain | Extracellular |
| Hgene | >ITGB5 | chr3:124578089 | chr4:95507559 | ENST00000296181 | - | 3 | 15 | 743_799 | 120 | 800 | Topological domain | Cytoplasmic |
| Hgene | >ITGB5 | chr3:124578089 | chr4:95507559 | ENST00000296181 | - | 3 | 15 | 720_742 | 120 | 800 | Transmembrane | Helical |
| Tgene | PDLIM5 | chr3:124578089 | chr4:95507559 | ENST00000317968 | + | 5 | 13 | 2_85 | 294 | 597 | Domain | PDZ |
| Tgene | PDLIM5 | chr3:124578089 | chr4:95507559 | ENST00000318007 | + | 7 | 10 | 2_85 | 171 | 215 | Domain | PDZ |
| Tgene | PDLIM5 | chr3:124578089 | chr4:95507559 | ENST00000380180 | + | 6 | 9 | 2_85 | 191 | 235 | Domain | PDZ |
| Tgene | PDLIM5 | chr3:124578089 | chr4:95507559 | ENST00000437932 | + | 5 | 13 | 2_85 | 185 | 488 | Domain | PDZ |
| Tgene | PDLIM5 | chr3:124578089 | chr4:95507559 | ENST00000508216 | + | 5 | 8 | 2_85 | 191 | 235 | Domain | PDZ |
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FusionGeneSequence for ITGB5_PDLIM5 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_ITGB5_ENST00000296181_chr3_124578089_-_PDLIM5_ENST00000450793_chr4_95507559_+_164aa MPRAPAPLYACLLGLCALLPRLAGLNICTSGSATSCEECLLIHPKCAWCSKEDFGSPRSITSRCDLRANLVKNGCGGEIESPASSFHVLR >In-frame_ITGB5_ENST00000296181_chr3_124578089_-_PDLIM5_ENST00000538141_chr4_95507559_+_164aa MPRAPAPLYACLLGLCALLPRLAGLNICTSGSATSCEECLLIHPKCAWCSKEDFGSPRSITSRCDLRANLVKNGCGGEIESPASSFHVLR >In-frame_ITGB5_ENST00000296181_chr3_124578089_-_PDLIM5_ENST00000380180_chr4_95507559_+_164aa MPRAPAPLYACLLGLCALLPRLAGLNICTSGSATSCEECLLIHPKCAWCSKEDFGSPRSITSRCDLRANLVKNGCGGEIESPASSFHVLR >In-frame_ITGB5_ENST00000296181_chr3_124578089_-_PDLIM5_ENST00000318007_chr4_95507559_+_164aa MPRAPAPLYACLLGLCALLPRLAGLNICTSGSATSCEECLLIHPKCAWCSKEDFGSPRSITSRCDLRANLVKNGCGGEIESPASSFHVLR >In-frame_ITGB5_ENST00000296181_chr3_124578089_-_PDLIM5_ENST00000437932_chr4_95507559_+_423aa MPRAPAPLYACLLGLCALLPRLAGLNICTSGSATSCEECLLIHPKCAWCSKEDFGSPRSITSRCDLRANLVKNGCGGEIESPASSFHVLR SLPLSSKGSGSAGWDVIQMTPQEIAVNLRPVKESEADNTKKANNSQEPSPQLASSVASTRSMPESLDSPTSGRPGVTSLTAAAAFKPVGS TGVIKSPSWQRPNQGVPSTGRISNSATYSGSVAPANSALGQTQPSDQDTLVQRAEHIPAGKRTPMCAHCNQVIRGPFLVALGKSWHPEEF NCAHCKNTMAYIGFVEEKGALYCELCYEKFFAPECGRCQRKILGEVISALKQTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALF >In-frame_ITGB5_ENST00000296181_chr3_124578089_-_PDLIM5_ENST00000317968_chr4_95507559_+_423aa MPRAPAPLYACLLGLCALLPRLAGLNICTSGSATSCEECLLIHPKCAWCSKEDFGSPRSITSRCDLRANLVKNGCGGEIESPASSFHVLR SLPLSSKGSGSAGWDVIQMTPQEIAVNLRPVKESEADNTKKANNSQEPSPQLASSVASTRSMPESLDSPTSGRPGVTSLTAAAAFKPVGS TGVIKSPSWQRPNQGVPSTGRISNSATYSGSVAPANSALGQTQPSDQDTLVQRAEHIPAGKRTPMCAHCNQVIRGPFLVALGKSWHPEEF NCAHCKNTMAYIGFVEEKGALYCELCYEKFFAPECGRCQRKILGEVISALKQTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALF >In-frame_ITGB5_ENST00000296181_chr3_124578089_-_PDLIM5_ENST00000542407_chr4_95507559_+_423aa MPRAPAPLYACLLGLCALLPRLAGLNICTSGSATSCEECLLIHPKCAWCSKEDFGSPRSITSRCDLRANLVKNGCGGEIESPASSFHVLR SLPLSSKGSGSAGWDVIQMTPQEIAVNLRPVKESEADNTKKANNSQEPSPQLASSVASTRSMPESLDSPTSGRPGVTSLTAAAAFKPVGS TGVIKSPSWQRPNQGVPSTGRISNSATYSGSVAPANSALGQTQPSDQDTLVQRAEHIPAGKRTPMCAHCNQVIRGPFLVALGKSWHPEEF NCAHCKNTMAYIGFVEEKGALYCELCYEKFFAPECGRCQRKILGEVISALKQTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALF >In-frame_ITGB5_ENST00000296181_chr3_124578089_-_PDLIM5_ENST00000508216_chr4_95507559_+_164aa MPRAPAPLYACLLGLCALLPRLAGLNICTSGSATSCEECLLIHPKCAWCSKEDFGSPRSITSRCDLRANLVKNGCGGEIESPASSFHVLR >In-frame_ITGB5_ENST00000296181_chr3_124578089_-_PDLIM5_ENST00000514743_chr4_95507559_+_555aa MPRAPAPLYACLLGLCALLPRLAGLNICTSGSATSCEECLLIHPKCAWCSKEDFGSPRSITSRCDLRANLVKNGCGGEIESPASSFHVLR SLPLSSKGSGSAGWDVIQMTPQEIAVNLRPVKESEADNTKKAKFDSALEDLPKSGPHPPATPQVLTIGSQVATLSKVATTYSSLSSSTGN VEDSFEGFRNFSTFSSPARYSAAVLSSAAATVSAVIATKTRLYTPERYHSLLDALCISPVSKPLAFSYLQSSRKSTGSIHVKKTSNSQEP SPQLASSVASTRSMPESLDSPTSGRPGVTSLTAAAAFKPVGSTGVIKSPSWQRPNQGVPSTGRISNSATYSGSVAPANSALGQTQPSDQD TLVQRAEHIPAGKRTPMCAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFAPECGRCQRKILGEVIS ALKQTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALFGTICHGCEFPIEAGDMFLEALGYTWHDTCFVCSVCCESLEGQTFFSKK |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_ITGB5_ENST00000296181_chr3_124578089_-_PDLIM5_ENST00000450793_chr4_95507559_+_492nt ATGCCGCGGGCCCCGGCGCCGCTGTACGCCTGCCTCCTGGGGCTCTGCGCGCTCCTGCCCCGGCTCGCAGGTCTCAACATATGCACTAGT GGAAGTGCCACCTCATGTGAAGAATGTCTGCTAATCCACCCAAAATGTGCCTGGTGCTCCAAAGAGGACTTCGGAAGCCCACGGTCCATC ACCTCTCGGTGTGATCTGAGGGCAAACCTTGTCAAAAATGGCTGTGGAGGTGAGATAGAGAGCCCAGCCAGCAGCTTCCATGTCCTGAGG AGCCTGCCCCTCAGCAGCAAGGGTTCGGGCTCTGCAGGCTGGGACGTCATTCAGATGACACCACAGGAGATTGCCGTGAACCTCCGGCCC GTGAAAGAATCTGAAGCCGATAATACAAAGAAGGCAAAGGAAAAGATACCCCTTCACGTCTTTAGTCCCAAATACACAAAATTACGTGAC >In-frame_ITGB5_ENST00000296181_chr3_124578089_-_PDLIM5_ENST00000538141_chr4_95507559_+_492nt ATGCCGCGGGCCCCGGCGCCGCTGTACGCCTGCCTCCTGGGGCTCTGCGCGCTCCTGCCCCGGCTCGCAGGTCTCAACATATGCACTAGT GGAAGTGCCACCTCATGTGAAGAATGTCTGCTAATCCACCCAAAATGTGCCTGGTGCTCCAAAGAGGACTTCGGAAGCCCACGGTCCATC ACCTCTCGGTGTGATCTGAGGGCAAACCTTGTCAAAAATGGCTGTGGAGGTGAGATAGAGAGCCCAGCCAGCAGCTTCCATGTCCTGAGG AGCCTGCCCCTCAGCAGCAAGGGTTCGGGCTCTGCAGGCTGGGACGTCATTCAGATGACACCACAGGAGATTGCCGTGAACCTCCGGCCC GTGAAAGAATCTGAAGCCGATAATACAAAGAAGGCAAAGGAAAAGATACCCCTTCACGTCTTTAGTCCCAAATACACAAAATTACGTGAC >In-frame_ITGB5_ENST00000296181_chr3_124578089_-_PDLIM5_ENST00000380180_chr4_95507559_+_492nt ATGCCGCGGGCCCCGGCGCCGCTGTACGCCTGCCTCCTGGGGCTCTGCGCGCTCCTGCCCCGGCTCGCAGGTCTCAACATATGCACTAGT GGAAGTGCCACCTCATGTGAAGAATGTCTGCTAATCCACCCAAAATGTGCCTGGTGCTCCAAAGAGGACTTCGGAAGCCCACGGTCCATC ACCTCTCGGTGTGATCTGAGGGCAAACCTTGTCAAAAATGGCTGTGGAGGTGAGATAGAGAGCCCAGCCAGCAGCTTCCATGTCCTGAGG AGCCTGCCCCTCAGCAGCAAGGGTTCGGGCTCTGCAGGCTGGGACGTCATTCAGATGACACCACAGGAGATTGCCGTGAACCTCCGGCCC GTGAAAGAATCTGAAGCCGATAATACAAAGAAGGCAAAGGAAAAGATACCCCTTCACGTCTTTAGTCCCAAATACACAAAATTACGTGAC >In-frame_ITGB5_ENST00000296181_chr3_124578089_-_PDLIM5_ENST00000318007_chr4_95507559_+_492nt ATGCCGCGGGCCCCGGCGCCGCTGTACGCCTGCCTCCTGGGGCTCTGCGCGCTCCTGCCCCGGCTCGCAGGTCTCAACATATGCACTAGT GGAAGTGCCACCTCATGTGAAGAATGTCTGCTAATCCACCCAAAATGTGCCTGGTGCTCCAAAGAGGACTTCGGAAGCCCACGGTCCATC ACCTCTCGGTGTGATCTGAGGGCAAACCTTGTCAAAAATGGCTGTGGAGGTGAGATAGAGAGCCCAGCCAGCAGCTTCCATGTCCTGAGG AGCCTGCCCCTCAGCAGCAAGGGTTCGGGCTCTGCAGGCTGGGACGTCATTCAGATGACACCACAGGAGATTGCCGTGAACCTCCGGCCC GTGAAAGAATCTGAAGCCGATAATACAAAGAAGGCAAAGGAAAAGATACCCCTTCACGTCTTTAGTCCCAAATACACAAAATTACGTGAC >In-frame_ITGB5_ENST00000296181_chr3_124578089_-_PDLIM5_ENST00000437932_chr4_95507559_+_1269nt ATGCCGCGGGCCCCGGCGCCGCTGTACGCCTGCCTCCTGGGGCTCTGCGCGCTCCTGCCCCGGCTCGCAGGTCTCAACATATGCACTAGT GGAAGTGCCACCTCATGTGAAGAATGTCTGCTAATCCACCCAAAATGTGCCTGGTGCTCCAAAGAGGACTTCGGAAGCCCACGGTCCATC ACCTCTCGGTGTGATCTGAGGGCAAACCTTGTCAAAAATGGCTGTGGAGGTGAGATAGAGAGCCCAGCCAGCAGCTTCCATGTCCTGAGG AGCCTGCCCCTCAGCAGCAAGGGTTCGGGCTCTGCAGGCTGGGACGTCATTCAGATGACACCACAGGAGATTGCCGTGAACCTCCGGCCC GTGAAAGAATCTGAAGCCGATAATACAAAGAAGGCAAATAACTCTCAGGAGCCTTCTCCGCAGTTGGCTTCCTCGGTAGCTTCCACACGG AGCATGCCCGAGAGCCTGGACAGCCCAACCTCTGGCAGACCAGGGGTTACCAGCCTCACAGCTGCAGCTGCCTTCAAGCCTGTAGGATCC ACTGGCGTCATCAAGTCACCAAGCTGGCAACGGCCAAACCAAGGAGTACCTTCCACTGGAAGAATCTCAAACAGCGCTACTTACTCAGGA TCAGTGGCACCAGCCAACTCAGCTTTGGGACAAACCCAGCCAAGTGACCAGGACACTTTAGTGCAAAGAGCTGAGCACATTCCAGCAGGG AAACGAACTCCGATGTGCGCCCATTGTAACCAGGTCATCAGAGGACCATTCTTAGTGGCACTGGGGAAATCTTGGCACCCAGAAGAATTC AACTGCGCTCACTGCAAAAATACAATGGCCTACATTGGATTTGTAGAGGAGAAAGGAGCCCTGTATTGTGAGCTGTGCTATGAGAAATTC TTTGCCCCTGAATGTGGTCGATGCCAAAGGAAGATCCTTGGAGAAGTCATCAGTGCGTTGAAACAAACTTGGCATGTTTCCTGTTTTGTG TGTGTAGCCTGTGGAAAGCCCATTCGGAACAATGTTTTTCACTTGGAGGATGGTGAACCCTACTGTGAGACTGATTATTATGCCCTCTTT GGTACTATATGCCATGGATGTGAATTTCCCATAGAAGCTGGTGACATGTTCCTGGAAGCTCTGGGCTACACCTGGCATGACACTTGCTTT GTATGCTCAGTGTGTTGTGAAAGTTTGGAAGGTCAGACCTTTTTCTCCAAGAAGGACAAGCCCCTGTGTAAGAAACATGCTCATTCTGTG >In-frame_ITGB5_ENST00000296181_chr3_124578089_-_PDLIM5_ENST00000317968_chr4_95507559_+_1269nt ATGCCGCGGGCCCCGGCGCCGCTGTACGCCTGCCTCCTGGGGCTCTGCGCGCTCCTGCCCCGGCTCGCAGGTCTCAACATATGCACTAGT GGAAGTGCCACCTCATGTGAAGAATGTCTGCTAATCCACCCAAAATGTGCCTGGTGCTCCAAAGAGGACTTCGGAAGCCCACGGTCCATC ACCTCTCGGTGTGATCTGAGGGCAAACCTTGTCAAAAATGGCTGTGGAGGTGAGATAGAGAGCCCAGCCAGCAGCTTCCATGTCCTGAGG AGCCTGCCCCTCAGCAGCAAGGGTTCGGGCTCTGCAGGCTGGGACGTCATTCAGATGACACCACAGGAGATTGCCGTGAACCTCCGGCCC GTGAAAGAATCTGAAGCCGATAATACAAAGAAGGCAAATAACTCTCAGGAGCCTTCTCCGCAGTTGGCTTCCTCGGTAGCTTCCACACGG AGCATGCCCGAGAGCCTGGACAGCCCAACCTCTGGCAGACCAGGGGTTACCAGCCTCACAGCTGCAGCTGCCTTCAAGCCTGTAGGATCC ACTGGCGTCATCAAGTCACCAAGCTGGCAACGGCCAAACCAAGGAGTACCTTCCACTGGAAGAATCTCAAACAGCGCTACTTACTCAGGA TCAGTGGCACCAGCCAACTCAGCTTTGGGACAAACCCAGCCAAGTGACCAGGACACTTTAGTGCAAAGAGCTGAGCACATTCCAGCAGGG AAACGAACTCCGATGTGCGCCCATTGTAACCAGGTCATCAGAGGACCATTCTTAGTGGCACTGGGGAAATCTTGGCACCCAGAAGAATTC AACTGCGCTCACTGCAAAAATACAATGGCCTACATTGGATTTGTAGAGGAGAAAGGAGCCCTGTATTGTGAGCTGTGCTATGAGAAATTC TTTGCCCCTGAATGTGGTCGATGCCAAAGGAAGATCCTTGGAGAAGTCATCAGTGCGTTGAAACAAACTTGGCATGTTTCCTGTTTTGTG TGTGTAGCCTGTGGAAAGCCCATTCGGAACAATGTTTTTCACTTGGAGGATGGTGAACCCTACTGTGAGACTGATTATTATGCCCTCTTT GGTACTATATGCCATGGATGTGAATTTCCCATAGAAGCTGGTGACATGTTCCTGGAAGCTCTGGGCTACACCTGGCATGACACTTGCTTT GTATGCTCAGTGTGTTGTGAAAGTTTGGAAGGTCAGACCTTTTTCTCCAAGAAGGACAAGCCCCTGTGTAAGAAACATGCTCATTCTGTG >In-frame_ITGB5_ENST00000296181_chr3_124578089_-_PDLIM5_ENST00000542407_chr4_95507559_+_1269nt ATGCCGCGGGCCCCGGCGCCGCTGTACGCCTGCCTCCTGGGGCTCTGCGCGCTCCTGCCCCGGCTCGCAGGTCTCAACATATGCACTAGT GGAAGTGCCACCTCATGTGAAGAATGTCTGCTAATCCACCCAAAATGTGCCTGGTGCTCCAAAGAGGACTTCGGAAGCCCACGGTCCATC ACCTCTCGGTGTGATCTGAGGGCAAACCTTGTCAAAAATGGCTGTGGAGGTGAGATAGAGAGCCCAGCCAGCAGCTTCCATGTCCTGAGG AGCCTGCCCCTCAGCAGCAAGGGTTCGGGCTCTGCAGGCTGGGACGTCATTCAGATGACACCACAGGAGATTGCCGTGAACCTCCGGCCC GTGAAAGAATCTGAAGCCGATAATACAAAGAAGGCAAATAACTCTCAGGAGCCTTCTCCGCAGTTGGCTTCCTCGGTAGCTTCCACACGG AGCATGCCCGAGAGCCTGGACAGCCCAACCTCTGGCAGACCAGGGGTTACCAGCCTCACAGCTGCAGCTGCCTTCAAGCCTGTAGGATCC ACTGGCGTCATCAAGTCACCAAGCTGGCAACGGCCAAACCAAGGAGTACCTTCCACTGGAAGAATCTCAAACAGCGCTACTTACTCAGGA TCAGTGGCACCAGCCAACTCAGCTTTGGGACAAACCCAGCCAAGTGACCAGGACACTTTAGTGCAAAGAGCTGAGCACATTCCAGCAGGG AAACGAACTCCGATGTGCGCCCATTGTAACCAGGTCATCAGAGGACCATTCTTAGTGGCACTGGGGAAATCTTGGCACCCAGAAGAATTC AACTGCGCTCACTGCAAAAATACAATGGCCTACATTGGATTTGTAGAGGAGAAAGGAGCCCTGTATTGTGAGCTGTGCTATGAGAAATTC TTTGCCCCTGAATGTGGTCGATGCCAAAGGAAGATCCTTGGAGAAGTCATCAGTGCGTTGAAACAAACTTGGCATGTTTCCTGTTTTGTG TGTGTAGCCTGTGGAAAGCCCATTCGGAACAATGTTTTTCACTTGGAGGATGGTGAACCCTACTGTGAGACTGATTATTATGCCCTCTTT GGTACTATATGCCATGGATGTGAATTTCCCATAGAAGCTGGTGACATGTTCCTGGAAGCTCTGGGCTACACCTGGCATGACACTTGCTTT GTATGCTCAGTGTGTTGTGAAAGTTTGGAAGGTCAGACCTTTTTCTCCAAGAAGGACAAGCCCCTGTGTAAGAAACATGCTCATTCTGTG >In-frame_ITGB5_ENST00000296181_chr3_124578089_-_PDLIM5_ENST00000508216_chr4_95507559_+_492nt ATGCCGCGGGCCCCGGCGCCGCTGTACGCCTGCCTCCTGGGGCTCTGCGCGCTCCTGCCCCGGCTCGCAGGTCTCAACATATGCACTAGT GGAAGTGCCACCTCATGTGAAGAATGTCTGCTAATCCACCCAAAATGTGCCTGGTGCTCCAAAGAGGACTTCGGAAGCCCACGGTCCATC ACCTCTCGGTGTGATCTGAGGGCAAACCTTGTCAAAAATGGCTGTGGAGGTGAGATAGAGAGCCCAGCCAGCAGCTTCCATGTCCTGAGG AGCCTGCCCCTCAGCAGCAAGGGTTCGGGCTCTGCAGGCTGGGACGTCATTCAGATGACACCACAGGAGATTGCCGTGAACCTCCGGCCC GTGAAAGAATCTGAAGCCGATAATACAAAGAAGGCAAAGGAAAAGATACCCCTTCACGTCTTTAGTCCCAAATACACAAAATTACGTGAC >In-frame_ITGB5_ENST00000296181_chr3_124578089_-_PDLIM5_ENST00000514743_chr4_95507559_+_1665nt ATGCCGCGGGCCCCGGCGCCGCTGTACGCCTGCCTCCTGGGGCTCTGCGCGCTCCTGCCCCGGCTCGCAGGTCTCAACATATGCACTAGT GGAAGTGCCACCTCATGTGAAGAATGTCTGCTAATCCACCCAAAATGTGCCTGGTGCTCCAAAGAGGACTTCGGAAGCCCACGGTCCATC ACCTCTCGGTGTGATCTGAGGGCAAACCTTGTCAAAAATGGCTGTGGAGGTGAGATAGAGAGCCCAGCCAGCAGCTTCCATGTCCTGAGG AGCCTGCCCCTCAGCAGCAAGGGTTCGGGCTCTGCAGGCTGGGACGTCATTCAGATGACACCACAGGAGATTGCCGTGAACCTCCGGCCC GTGAAAGAATCTGAAGCCGATAATACAAAGAAGGCAAAGTTTGACAGTGCTCTGGAAGACCTACCTAAGAGTGGACCTCACCCTCCTGCA ACTCCTCAGGTGTTAACTATTGGTAGCCAAGTGGCCACACTTTCTAAAGTAGCAACTACTTATTCTAGTTTAAGCAGCTCCACAGGAAAT GTGGAAGATTCTTTCGAAGGTTTTCGAAACTTTTCTACCTTCTCTTCTCCTGCTAGATATAGTGCTGCAGTTCTGAGCAGCGCAGCTGCT ACTGTGTCTGCTGTTATTGCTACAAAAACCAGGCTCTACACTCCTGAAAGATATCACTCACTCCTGGATGCACTTTGCATCAGCCCTGTC TCCAAGCCTTTAGCTTTTTCCTATCTGCAGTCCTCAAGGAAATCAACTGGCTCTATCCATGTTAAGAAAACAAGTAACTCTCAGGAGCCT TCTCCGCAGTTGGCTTCCTCGGTAGCTTCCACACGGAGCATGCCCGAGAGCCTGGACAGCCCAACCTCTGGCAGACCAGGGGTTACCAGC CTCACAGCTGCAGCTGCCTTCAAGCCTGTAGGATCCACTGGCGTCATCAAGTCACCAAGCTGGCAACGGCCAAACCAAGGAGTACCTTCC ACTGGAAGAATCTCAAACAGCGCTACTTACTCAGGATCAGTGGCACCAGCCAACTCAGCTTTGGGACAAACCCAGCCAAGTGACCAGGAC ACTTTAGTGCAAAGAGCTGAGCACATTCCAGCAGGGAAACGAACTCCGATGTGCGCCCATTGTAACCAGGTCATCAGAGGACCATTCTTA GTGGCACTGGGGAAATCTTGGCACCCAGAAGAATTCAACTGCGCTCACTGCAAAAATACAATGGCCTACATTGGATTTGTAGAGGAGAAA GGAGCCCTGTATTGTGAGCTGTGCTATGAGAAATTCTTTGCCCCTGAATGTGGTCGATGCCAAAGGAAGATCCTTGGAGAAGTCATCAGT GCGTTGAAACAAACTTGGCATGTTTCCTGTTTTGTGTGTGTAGCCTGTGGAAAGCCCATTCGGAACAATGTTTTTCACTTGGAGGATGGT GAACCCTACTGTGAGACTGATTATTATGCCCTCTTTGGTACTATATGCCATGGATGTGAATTTCCCATAGAAGCTGGTGACATGTTCCTG GAAGCTCTGGGCTACACCTGGCATGACACTTGCTTTGTATGCTCAGTGTGTTGTGAAAGTTTGGAAGGTCAGACCTTTTTCTCCAAGAAG |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_ITGB5_ENST00000296181_chr3_124578089_-_PDLIM5_ENST00000450793_chr4_95507559_+_789nt GCGGAGCCAGCCCCTCCCCTACCCGGAGCAGCCCGCTGGGGCCGTCCCGAGCGGCGACACACTAGGAGTCCCGGCCGGCCAGCCAGGGCA GCCGCGGTCCCGGGACTCGGCCGTGAGTGCTGCGGGACGGATGGTGGCGGCGGGGCGCGGGCCAGCGCGGGCGCCGTGAGCCGGAGCTGC GCGCGGGGCATGCGGCTGCGGCCCCCGGCCCTCGGCCCCCGCGCTCCGGCCCCAGCCCCGGCCGCCGGCCCCCGCGGAGTGCAGCGACCG CGCCGCCGCTGAGGGAGGCGCCCCACCATGCCGCGGGCCCCGGCGCCGCTGTACGCCTGCCTCCTGGGGCTCTGCGCGCTCCTGCCCCGG CTCGCAGGTCTCAACATATGCACTAGTGGAAGTGCCACCTCATGTGAAGAATGTCTGCTAATCCACCCAAAATGTGCCTGGTGCTCCAAA GAGGACTTCGGAAGCCCACGGTCCATCACCTCTCGGTGTGATCTGAGGGCAAACCTTGTCAAAAATGGCTGTGGAGGTGAGATAGAGAGC CCAGCCAGCAGCTTCCATGTCCTGAGGAGCCTGCCCCTCAGCAGCAAGGGTTCGGGCTCTGCAGGCTGGGACGTCATTCAGATGACACCA CAGGAGATTGCCGTGAACCTCCGGCCCGTGAAAGAATCTGAAGCCGATAATACAAAGAAGGCAAAGGAAAAGATACCCCTTCACGTCTTT >In-frame_ITGB5_ENST00000296181_chr3_124578089_-_PDLIM5_ENST00000538141_chr4_95507559_+_789nt GCGGAGCCAGCCCCTCCCCTACCCGGAGCAGCCCGCTGGGGCCGTCCCGAGCGGCGACACACTAGGAGTCCCGGCCGGCCAGCCAGGGCA GCCGCGGTCCCGGGACTCGGCCGTGAGTGCTGCGGGACGGATGGTGGCGGCGGGGCGCGGGCCAGCGCGGGCGCCGTGAGCCGGAGCTGC GCGCGGGGCATGCGGCTGCGGCCCCCGGCCCTCGGCCCCCGCGCTCCGGCCCCAGCCCCGGCCGCCGGCCCCCGCGGAGTGCAGCGACCG CGCCGCCGCTGAGGGAGGCGCCCCACCATGCCGCGGGCCCCGGCGCCGCTGTACGCCTGCCTCCTGGGGCTCTGCGCGCTCCTGCCCCGG CTCGCAGGTCTCAACATATGCACTAGTGGAAGTGCCACCTCATGTGAAGAATGTCTGCTAATCCACCCAAAATGTGCCTGGTGCTCCAAA GAGGACTTCGGAAGCCCACGGTCCATCACCTCTCGGTGTGATCTGAGGGCAAACCTTGTCAAAAATGGCTGTGGAGGTGAGATAGAGAGC CCAGCCAGCAGCTTCCATGTCCTGAGGAGCCTGCCCCTCAGCAGCAAGGGTTCGGGCTCTGCAGGCTGGGACGTCATTCAGATGACACCA CAGGAGATTGCCGTGAACCTCCGGCCCGTGAAAGAATCTGAAGCCGATAATACAAAGAAGGCAAAGGAAAAGATACCCCTTCACGTCTTT >In-frame_ITGB5_ENST00000296181_chr3_124578089_-_PDLIM5_ENST00000380180_chr4_95507559_+_1923nt GCGGAGCCAGCCCCTCCCCTACCCGGAGCAGCCCGCTGGGGCCGTCCCGAGCGGCGACACACTAGGAGTCCCGGCCGGCCAGCCAGGGCA GCCGCGGTCCCGGGACTCGGCCGTGAGTGCTGCGGGACGGATGGTGGCGGCGGGGCGCGGGCCAGCGCGGGCGCCGTGAGCCGGAGCTGC GCGCGGGGCATGCGGCTGCGGCCCCCGGCCCTCGGCCCCCGCGCTCCGGCCCCAGCCCCGGCCGCCGGCCCCCGCGGAGTGCAGCGACCG CGCCGCCGCTGAGGGAGGCGCCCCACCATGCCGCGGGCCCCGGCGCCGCTGTACGCCTGCCTCCTGGGGCTCTGCGCGCTCCTGCCCCGG CTCGCAGGTCTCAACATATGCACTAGTGGAAGTGCCACCTCATGTGAAGAATGTCTGCTAATCCACCCAAAATGTGCCTGGTGCTCCAAA GAGGACTTCGGAAGCCCACGGTCCATCACCTCTCGGTGTGATCTGAGGGCAAACCTTGTCAAAAATGGCTGTGGAGGTGAGATAGAGAGC CCAGCCAGCAGCTTCCATGTCCTGAGGAGCCTGCCCCTCAGCAGCAAGGGTTCGGGCTCTGCAGGCTGGGACGTCATTCAGATGACACCA CAGGAGATTGCCGTGAACCTCCGGCCCGTGAAAGAATCTGAAGCCGATAATACAAAGAAGGCAAAGGAAAAGATACCCCTTCACGTCTTT AGTCCCAAATACACAAAATTACGTGACTGGCACCATGAAGTTTCAGCACGTGCTCTTAACGTACAGTGATTTATGAGCCTTGCCCCCCAA GCAGCCAGCACATACCTTTTCATTTACTTTTTTTTTTTCAACTTCATAGCAAAATCTGTATTAAATTTGCCTTATGAAAAAATAGAACTT TTTCTATACTTTTCTAACAATTTCCTATTGTTGTGAGAAAAGGAAGATGAACATGTTTTGTGCTAGTTGGTAGCTCACAAATGTAAAACC AAAAAAAAAAAAAAATAGAAAATTAAGGGACTAGATCTATTTGTGGATTTGTATCTGTTTTTGTTGTGATTAGGGTAGTAATCTTGGAAA ACGAATTATTTTCATAAGTTGAATTTGGTTAGTTGGTTGGTTGAAGCAGAGGATAATGAGCAAATAAAGTCCTTGTCTAATTTGGAAAAT ACTTTCTTTATATTATTAACATCTCCCAAGATTACTTTTTAAGTTCATTATTATGTTACATTCAAAGTTGATTGTAAATTATTCTAAATA AGTAAATATAAGGAGGCAAGAATAAACAAAGACTTTATTAAAGAAGAGTGCGTGCATTGTAGATTTAGGTATCTTTTAAAGTAGGTACTA TTCAGGATGGCTCTATGAAGAGGAGGAGGTCCAGATTTGGCTCCTGAAAAAGGAAAGAAGAGAATTTTACCCCTATTTGCAATGGAGAAA TACAGTATTCTTTGGTTTGGTTGGATTTGCAAATCCTATTTCCTATCAAAGGAAATATCTCTAGTGGATATTTTTAGAATATAGACAATT TCTAGGTATTAACTAATAAGATATGGAAAAGATAGCTTTGCTTTTTTTAATCAGAAGAACATAAAATAAATTACAATATGAATGATTGTG AGACATCAGAGAAATATTTTACTTAGTGACGTAAACTACTGTGCACTGCTGCTATTCCTAGGAAGCTGTGTTTTGGGCAATACATGGAAG CTAAATATATGACCAGAAATGCTTTCTGCCTTGTAATATAGTGTATTATATATTAGAGCTAAATTTAGTAATAAATGCATTTTGAAGTTT GGAAAAGTATTGTAATAAAGTTGCCTTTAACTTAGCTTTGTACTTGTTCTGTTTCCTTGAGGCTAGACACAGTGCCATCCAGGACTTATT >In-frame_ITGB5_ENST00000296181_chr3_124578089_-_PDLIM5_ENST00000318007_chr4_95507559_+_1923nt GCGGAGCCAGCCCCTCCCCTACCCGGAGCAGCCCGCTGGGGCCGTCCCGAGCGGCGACACACTAGGAGTCCCGGCCGGCCAGCCAGGGCA GCCGCGGTCCCGGGACTCGGCCGTGAGTGCTGCGGGACGGATGGTGGCGGCGGGGCGCGGGCCAGCGCGGGCGCCGTGAGCCGGAGCTGC GCGCGGGGCATGCGGCTGCGGCCCCCGGCCCTCGGCCCCCGCGCTCCGGCCCCAGCCCCGGCCGCCGGCCCCCGCGGAGTGCAGCGACCG CGCCGCCGCTGAGGGAGGCGCCCCACCATGCCGCGGGCCCCGGCGCCGCTGTACGCCTGCCTCCTGGGGCTCTGCGCGCTCCTGCCCCGG CTCGCAGGTCTCAACATATGCACTAGTGGAAGTGCCACCTCATGTGAAGAATGTCTGCTAATCCACCCAAAATGTGCCTGGTGCTCCAAA GAGGACTTCGGAAGCCCACGGTCCATCACCTCTCGGTGTGATCTGAGGGCAAACCTTGTCAAAAATGGCTGTGGAGGTGAGATAGAGAGC CCAGCCAGCAGCTTCCATGTCCTGAGGAGCCTGCCCCTCAGCAGCAAGGGTTCGGGCTCTGCAGGCTGGGACGTCATTCAGATGACACCA CAGGAGATTGCCGTGAACCTCCGGCCCGTGAAAGAATCTGAAGCCGATAATACAAAGAAGGCAAAGGAAAAGATACCCCTTCACGTCTTT AGTCCCAAATACACAAAATTACGTGACTGGCACCATGAAGTTTCAGCACGTGCTCTTAACGTACAGTGATTTATGAGCCTTGCCCCCCAA GCAGCCAGCACATACCTTTTCATTTACTTTTTTTTTTTCAACTTCATAGCAAAATCTGTATTAAATTTGCCTTATGAAAAAATAGAACTT TTTCTATACTTTTCTAACAATTTCCTATTGTTGTGAGAAAAGGAAGATGAACATGTTTTGTGCTAGTTGGTAGCTCACAAATGTAAAACC AAAAAAAAAAAAAAATAGAAAATTAAGGGACTAGATCTATTTGTGGATTTGTATCTGTTTTTGTTGTGATTAGGGTAGTAATCTTGGAAA ACGAATTATTTTCATAAGTTGAATTTGGTTAGTTGGTTGGTTGAAGCAGAGGATAATGAGCAAATAAAGTCCTTGTCTAATTTGGAAAAT ACTTTCTTTATATTATTAACATCTCCCAAGATTACTTTTTAAGTTCATTATTATGTTACATTCAAAGTTGATTGTAAATTATTCTAAATA AGTAAATATAAGGAGGCAAGAATAAACAAAGACTTTATTAAAGAAGAGTGCGTGCATTGTAGATTTAGGTATCTTTTAAAGTAGGTACTA TTCAGGATGGCTCTATGAAGAGGAGGAGGTCCAGATTTGGCTCCTGAAAAAGGAAAGAAGAGAATTTTACCCCTATTTGCAATGGAGAAA TACAGTATTCTTTGGTTTGGTTGGATTTGCAAATCCTATTTCCTATCAAAGGAAATATCTCTAGTGGATATTTTTAGAATATAGACAATT TCTAGGTATTAACTAATAAGATATGGAAAAGATAGCTTTGCTTTTTTTAATCAGAAGAACATAAAATAAATTACAATATGAATGATTGTG AGACATCAGAGAAATATTTTACTTAGTGACGTAAACTACTGTGCACTGCTGCTATTCCTAGGAAGCTGTGTTTTGGGCAATACATGGAAG CTAAATATATGACCAGAAATGCTTTCTGCCTTGTAATATAGTGTATTATATATTAGAGCTAAATTTAGTAATAAATGCATTTTGAAGTTT GGAAAAGTATTGTAATAAAGTTGCCTTTAACTTAGCTTTGTACTTGTTCTGTTTCCTTGAGGCTAGACACAGTGCCATCCAGGACTTATT >In-frame_ITGB5_ENST00000296181_chr3_124578089_-_PDLIM5_ENST00000437932_chr4_95507559_+_5725nt GCGGAGCCAGCCCCTCCCCTACCCGGAGCAGCCCGCTGGGGCCGTCCCGAGCGGCGACACACTAGGAGTCCCGGCCGGCCAGCCAGGGCA GCCGCGGTCCCGGGACTCGGCCGTGAGTGCTGCGGGACGGATGGTGGCGGCGGGGCGCGGGCCAGCGCGGGCGCCGTGAGCCGGAGCTGC GCGCGGGGCATGCGGCTGCGGCCCCCGGCCCTCGGCCCCCGCGCTCCGGCCCCAGCCCCGGCCGCCGGCCCCCGCGGAGTGCAGCGACCG CGCCGCCGCTGAGGGAGGCGCCCCACCATGCCGCGGGCCCCGGCGCCGCTGTACGCCTGCCTCCTGGGGCTCTGCGCGCTCCTGCCCCGG CTCGCAGGTCTCAACATATGCACTAGTGGAAGTGCCACCTCATGTGAAGAATGTCTGCTAATCCACCCAAAATGTGCCTGGTGCTCCAAA GAGGACTTCGGAAGCCCACGGTCCATCACCTCTCGGTGTGATCTGAGGGCAAACCTTGTCAAAAATGGCTGTGGAGGTGAGATAGAGAGC CCAGCCAGCAGCTTCCATGTCCTGAGGAGCCTGCCCCTCAGCAGCAAGGGTTCGGGCTCTGCAGGCTGGGACGTCATTCAGATGACACCA CAGGAGATTGCCGTGAACCTCCGGCCCGTGAAAGAATCTGAAGCCGATAATACAAAGAAGGCAAATAACTCTCAGGAGCCTTCTCCGCAG TTGGCTTCCTCGGTAGCTTCCACACGGAGCATGCCCGAGAGCCTGGACAGCCCAACCTCTGGCAGACCAGGGGTTACCAGCCTCACAGCT GCAGCTGCCTTCAAGCCTGTAGGATCCACTGGCGTCATCAAGTCACCAAGCTGGCAACGGCCAAACCAAGGAGTACCTTCCACTGGAAGA ATCTCAAACAGCGCTACTTACTCAGGATCAGTGGCACCAGCCAACTCAGCTTTGGGACAAACCCAGCCAAGTGACCAGGACACTTTAGTG CAAAGAGCTGAGCACATTCCAGCAGGGAAACGAACTCCGATGTGCGCCCATTGTAACCAGGTCATCAGAGGACCATTCTTAGTGGCACTG GGGAAATCTTGGCACCCAGAAGAATTCAACTGCGCTCACTGCAAAAATACAATGGCCTACATTGGATTTGTAGAGGAGAAAGGAGCCCTG TATTGTGAGCTGTGCTATGAGAAATTCTTTGCCCCTGAATGTGGTCGATGCCAAAGGAAGATCCTTGGAGAAGTCATCAGTGCGTTGAAA CAAACTTGGCATGTTTCCTGTTTTGTGTGTGTAGCCTGTGGAAAGCCCATTCGGAACAATGTTTTTCACTTGGAGGATGGTGAACCCTAC TGTGAGACTGATTATTATGCCCTCTTTGGTACTATATGCCATGGATGTGAATTTCCCATAGAAGCTGGTGACATGTTCCTGGAAGCTCTG GGCTACACCTGGCATGACACTTGCTTTGTATGCTCAGTGTGTTGTGAAAGTTTGGAAGGTCAGACCTTTTTCTCCAAGAAGGACAAGCCC CTGTGTAAGAAACATGCTCATTCTGTGAATTTTTGAAAGTCAACAGTTCAGGAGAAGAGAAGGAATTTGAAGAGAAAAAGGAAAATTAAA ATTACTAATTAATTTTTAGATTCAATATTTATATGGAGTTTTGAAAAATAATAGTGGCCCTGAAGGAATAAATTCCAGCTTTAAAAACCA AGTCTGAGGAAATATTTGGCTTCATAAAGTAAAGAGACGGTTTGGCATTTATTATTACTTTTTCCTGTATTTTATGCCCATAAAATAAGC TTTATAAAAACCAATTTCCTGATGGACTATTAAATTCATCTTAGAATAAATTAGTGAAGAATTTAATTTTAGAATAAATAATCCAATCTG AAATAATTATACCTTCTTTCCTTGTTAGGTAGTTATGAGTAAATCTGCAAAAGGCAATGAAAATGCCTTAAATTTTATCAATAACAGAAT TATTGTATTTAAAAAAAAACTAATACTTATCTTTAAAATAGTAAATAGGATTTTAAACAGAGAATTTTATCAGTAATAGGTGTCAGTTTT TAAAAAATTGCTTGTAGGCTGAGCGCGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCAAGGTGGGTGGACCACATGAGGTCAG GAGTTTGAGATCAGCCTGGCCAACATGGTGAAACCCCATCTCTACTAAAAATACAAAAATTAGCCGGACGCAGTGGCACGCGCCTGTAAT CCCAGCTACTCAAGAGGCTGAGGCACGAGAATCACTTGAACCCGGGAGGGAGAGGTTGCAGTGAGCCAAGATCGTACCACTGCACTCCAG CCTGGGTGACAGAGTGAGACTCTGTCTCCAAAAAAAAACTTTGCTTGTATATTATTTTTGCCTTACAGTGGATCATTCTAGTAGGAAAGG ACAATAAGATTTTTTATCAAAATGTGTCATGCCAGTAAGAGATGTTATATTCTTTTCTCATTTCTTCCCCACCCAAAAATAAGCTACCAT ATAGCTTATAAGTCTCAAATTTTTGCCTTTTACTAAAATGTGATTGTTTCTATTCATTGTGTATGCTTCATCACCTATATTAGGCAAATT CCATTTTTTTCCCTTGTGCTAAGGTAAAGATTTAATTAAATAATTTTGGCCTCTCATAGTTTTCTCTCTCTTTAAAGAGAATAAATAGAG GGCCAGGTGTGGTGGCTCACGCCTGTGATCCCAGCACTTTGGGAGGCCAAGACGGGCGGATCATGAGGTCAAGAGATCAAGATCATCCTG GCCAACATGGTGAAACCCTGTCTCTACTAAAAATACAAAAATGAGCTGGGCATGGTGGGGCGTGCCTGTAGTCCCATGTACTTGGGAGGC TGAGGCAGGAAAATTCTTGAACCCAGGAGACGGAAGTTGCAGTGAGCTGAGATCACACCACTGCACTCCAGCCTGGTGACAGAGCAAGAC TCCGGCTCTTAAAAAAAAAAAAAAAAAAAAAAAAAGAGAGAGAGAGAATAAATAGAAAAGAATGTGGCTGGGAATTGTGAATCAGAAGAT TATACCCCCCAATTGTTTTTCAATCCCCTTTTCTCAAATAATAAATTAGTTAAATCAGTTTCTGAGTTATGCCACTGGCTGATGAAGAGT TGAGAGGTCTCTTTGCAGAATGATCTTTTTGTTTCGTTTTGTTTCTTCTTCTGCATTTAAAAATTAAAAGATTGGTTTGAGGATGTGATG AAATTGAGACTTTTTGTGGTTTTCTCTCAATAATAAGTGAACCAATTTCAAATGTGATCACAAAGTTTGGAAAGCTTTTATTCACAGAGG TTGGGTAGTGTTGGGAGGGGAGTTTAATTACTCAGATTGGCCTGTTATTTGATTTCCTCCTTTGGGAAAAGAATTATGTAGATACCACAT GGAGACAGGGAAACAATTGTGGTAAAACTGTGGATCCTGTTGCTATTTGCCCAGTGAGAAAACAGATTCTGGTATTTGATTTGGTTTTTC TCTTTGTTTCCAGAATGGATGAAAGTCCATGAACCTCCTAAGTTATAATTTAAATTTGTTTGGGGCAAGGTGATTTTATAGTCGAGACAG AGCCCTAGGTCCTTCCTGCCCCATCACTCACTTACGACATCACTTCCATTGTGTGCATGTTTGTTATAGAGGAGGTTTTAGGCTACAATA TTTGTTTAACCTCCCTAAGAACTTTCAAGGCATCTGTCCTGAAAGCTGTTAATTTATGGTCTAGCAGATTTATATTATATGCAGATAATA ATTAACTGGGGATAAAAGAATGGCAAGGGGTGACACAAAGTAGCAAACTGAATACTTCTCCAATAGCAACCCCAAGCTACCTCCTCACCC TGCATCTTGGAGGGAGGCAGGAAATTTCTTTTGAAATAAAGTGCTGGAGCTGAATTCTGCATTATTTATCGTTGCTGCTGAAACCACCTA TAAAAGACTTGCTGGCTAATGTGCATTGTCATATAATGTACACTGTCACATCTTTACAGTCTTGTATGTTATAGAATACAAAATAAGTTG ATGGTTTTGTTTGGTGTGAGCTTTTTGTTTGTTTGTTTAGTTTTGCCTTCATAGGTTATATGCCAAGATAGTATTTGATAAGTCAATGAC ATTTGGATGTTTTCTTCAAAGAATTTTATTTGACCCAGATTTCTTATAAAGTTATCTTACATTAAGGATGTCATTTTCATCAGACCTTCT TTCTACATATTATTCATGAAGCATAATGTTGCATTTCTCCAAATTTTATGCCTGAAAGGGTAGTGTTGCTTCCTAAGGTATCATGTTGTC TTTGTGCTTTGTCCATCTCTTCCGTGGCGAAGCTTTATATCTGTTCCTAAAACAGTTAATCCTGTGAAATAAATATTGAACATAATCCAG AAGAATCTCTCTGTTTCCCTTGGGGAATGCCATATTTAATTCACCAGCAGTAATCCTTTAATAACTGGCAGAGCACTTTATTCTTCTGGT GAGCTCCCTGAATATTTATTTTTCTGATTATAAATTTTCTATATTAGTAGCATTTTTTAATTATTACTTCTTCACTATAGAGCATTTACT TTTAGTCTCTAGATGTATATTTTGGAATGCTGTACTTGGCATAACATAGATTAAAATCATAATGCATGACTAAAAACTCCTTGGATTTAT TTCCCATTTTAAAATTTTTAGCGGTAAGTTCAGATTTATAATCTTTCTCTAGACTTCCATGGTCTGAATGTTGCCTGCTGAAGTAGCAAC CTAAAAAGTATCCCCTGCTTATGCTTGTCCAGTTGGCCCTCCATGTCCATAGGCTTCGCATCTGTGATTCAGCCCACTGTGGGTCAAAAA TATTTGGGGAAAAAAATGGATGGTTGCGCCTTTGCTGAACATGTACAAACTTTTTTTTGTCATTAAACAATATAGTATAACAACTATTTA CAAAGCATTTACATTGTATTAGCTATTATAGGTAATCTAGAGATGATTTAAAGTGTATGGTAGGATGTGCATAGGTTATATGCAAATACT ACACCATTTTCTATAAGGGACTTGAACATCATGGACTTTAGTATCCTAGGGGGTTCTTGGAACCCATCACCCATAGGGGCACCATAGGAC AACTATAGTACCGTGTTTATTTCCTATTAATTCAGGTTCCGTTTAGAGTCTAAAACTAAAACCTAATCATTTAGTCACAGTGTAAAAACA AATGGAAATAACAGCTCAAATCTTCAAAATATTACTATAGCATTATGTTTAAAATAATCTACAACAAAAATGTACCATTTTCAAGCAGTA CTACATTAGGAGCCCTTTTATAGAAAATAATTTCTTCTTTACCCCCGTTCCAGTGTGAATCTAGTATTCTGTTAACATTTGTGTGGCATT TGGAGTTTGTCATCCCCATTGAAGGGAGAGCCTTCTCAGACATGAAGCAAGGGAAACATACTGAATAGTTTTACACAAATTTGATCTGGC TTCCATTTGTCCCCCTCATTTCCCAAATGTTTAAATGTATTGGATTTGGATTCTCAATGTATAAGTTGCCTTATCTGTTAATGTCTATCT TCTGTCTCTTTAATTTTGTATATCTGCTGTTTTGCTTTTGGATACATTTTCTAATTAGAAGTCACATGATAAATATAATCAGTATAGTAA >In-frame_ITGB5_ENST00000296181_chr3_124578089_-_PDLIM5_ENST00000317968_chr4_95507559_+_5722nt GCGGAGCCAGCCCCTCCCCTACCCGGAGCAGCCCGCTGGGGCCGTCCCGAGCGGCGACACACTAGGAGTCCCGGCCGGCCAGCCAGGGCA GCCGCGGTCCCGGGACTCGGCCGTGAGTGCTGCGGGACGGATGGTGGCGGCGGGGCGCGGGCCAGCGCGGGCGCCGTGAGCCGGAGCTGC GCGCGGGGCATGCGGCTGCGGCCCCCGGCCCTCGGCCCCCGCGCTCCGGCCCCAGCCCCGGCCGCCGGCCCCCGCGGAGTGCAGCGACCG CGCCGCCGCTGAGGGAGGCGCCCCACCATGCCGCGGGCCCCGGCGCCGCTGTACGCCTGCCTCCTGGGGCTCTGCGCGCTCCTGCCCCGG CTCGCAGGTCTCAACATATGCACTAGTGGAAGTGCCACCTCATGTGAAGAATGTCTGCTAATCCACCCAAAATGTGCCTGGTGCTCCAAA GAGGACTTCGGAAGCCCACGGTCCATCACCTCTCGGTGTGATCTGAGGGCAAACCTTGTCAAAAATGGCTGTGGAGGTGAGATAGAGAGC CCAGCCAGCAGCTTCCATGTCCTGAGGAGCCTGCCCCTCAGCAGCAAGGGTTCGGGCTCTGCAGGCTGGGACGTCATTCAGATGACACCA CAGGAGATTGCCGTGAACCTCCGGCCCGTGAAAGAATCTGAAGCCGATAATACAAAGAAGGCAAATAACTCTCAGGAGCCTTCTCCGCAG TTGGCTTCCTCGGTAGCTTCCACACGGAGCATGCCCGAGAGCCTGGACAGCCCAACCTCTGGCAGACCAGGGGTTACCAGCCTCACAGCT GCAGCTGCCTTCAAGCCTGTAGGATCCACTGGCGTCATCAAGTCACCAAGCTGGCAACGGCCAAACCAAGGAGTACCTTCCACTGGAAGA ATCTCAAACAGCGCTACTTACTCAGGATCAGTGGCACCAGCCAACTCAGCTTTGGGACAAACCCAGCCAAGTGACCAGGACACTTTAGTG CAAAGAGCTGAGCACATTCCAGCAGGGAAACGAACTCCGATGTGCGCCCATTGTAACCAGGTCATCAGAGGACCATTCTTAGTGGCACTG GGGAAATCTTGGCACCCAGAAGAATTCAACTGCGCTCACTGCAAAAATACAATGGCCTACATTGGATTTGTAGAGGAGAAAGGAGCCCTG TATTGTGAGCTGTGCTATGAGAAATTCTTTGCCCCTGAATGTGGTCGATGCCAAAGGAAGATCCTTGGAGAAGTCATCAGTGCGTTGAAA CAAACTTGGCATGTTTCCTGTTTTGTGTGTGTAGCCTGTGGAAAGCCCATTCGGAACAATGTTTTTCACTTGGAGGATGGTGAACCCTAC TGTGAGACTGATTATTATGCCCTCTTTGGTACTATATGCCATGGATGTGAATTTCCCATAGAAGCTGGTGACATGTTCCTGGAAGCTCTG GGCTACACCTGGCATGACACTTGCTTTGTATGCTCAGTGTGTTGTGAAAGTTTGGAAGGTCAGACCTTTTTCTCCAAGAAGGACAAGCCC CTGTGTAAGAAACATGCTCATTCTGTGAATTTTTGAAAGTCAACAGTTCAGGAGAAGAGAAGGAATTTGAAGAGAAAAAGGAAAATTAAA ATTACTAATTAATTTTTAGATTCAATATTTATATGGAGTTTTGAAAAATAATAGTGGCCCTGAAGGAATAAATTCCAGCTTTAAAAACCA AGTCTGAGGAAATATTTGGCTTCATAAAGTAAAGAGACGGTTTGGCATTTATTATTACTTTTTCCTGTATTTTATGCCCATAAAATAAGC TTTATAAAAACCAATTTCCTGATGGACTATTAAATTCATCTTAGAATAAATTAGTGAAGAATTTAATTTTAGAATAAATAATCCAATCTG AAATAATTATACCTTCTTTCCTTGTTAGGTAGTTATGAGTAAATCTGCAAAAGGCAATGAAAATGCCTTAAATTTTATCAATAACAGAAT TATTGTATTTAAAAAAAAACTAATACTTATCTTTAAAATAGTAAATAGGATTTTAAACAGAGAATTTTATCAGTAATAGGTGTCAGTTTT TAAAAAATTGCTTGTAGGCTGAGCGCGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCAAGGTGGGTGGACCACATGAGGTCAG GAGTTTGAGATCAGCCTGGCCAACATGGTGAAACCCCATCTCTACTAAAAATACAAAAATTAGCCGGACGCAGTGGCACGCGCCTGTAAT CCCAGCTACTCAAGAGGCTGAGGCACGAGAATCACTTGAACCCGGGAGGGAGAGGTTGCAGTGAGCCAAGATCGTACCACTGCACTCCAG CCTGGGTGACAGAGTGAGACTCTGTCTCCAAAAAAAAACTTTGCTTGTATATTATTTTTGCCTTACAGTGGATCATTCTAGTAGGAAAGG ACAATAAGATTTTTTATCAAAATGTGTCATGCCAGTAAGAGATGTTATATTCTTTTCTCATTTCTTCCCCACCCAAAAATAAGCTACCAT ATAGCTTATAAGTCTCAAATTTTTGCCTTTTACTAAAATGTGATTGTTTCTATTCATTGTGTATGCTTCATCACCTATATTAGGCAAATT CCATTTTTTTCCCTTGTGCTAAGGTAAAGATTTAATTAAATAATTTTGGCCTCTCATAGTTTTCTCTCTCTTTAAAGAGAATAAATAGAG GGCCAGGTGTGGTGGCTCACGCCTGTGATCCCAGCACTTTGGGAGGCCAAGACGGGCGGATCATGAGGTCAAGAGATCAAGATCATCCTG GCCAACATGGTGAAACCCTGTCTCTACTAAAAATACAAAAATGAGCTGGGCATGGTGGGGCGTGCCTGTAGTCCCATGTACTTGGGAGGC TGAGGCAGGAAAATTCTTGAACCCAGGAGACGGAAGTTGCAGTGAGCTGAGATCACACCACTGCACTCCAGCCTGGTGACAGAGCAAGAC TCCGGCTCTTAAAAAAAAAAAAAAAAAAAAAAAAAGAGAGAGAGAGAATAAATAGAAAAGAATGTGGCTGGGAATTGTGAATCAGAAGAT TATACCCCCCAATTGTTTTTCAATCCCCTTTTCTCAAATAATAAATTAGTTAAATCAGTTTCTGAGTTATGCCACTGGCTGATGAAGAGT TGAGAGGTCTCTTTGCAGAATGATCTTTTTGTTTCGTTTTGTTTCTTCTTCTGCATTTAAAAATTAAAAGATTGGTTTGAGGATGTGATG AAATTGAGACTTTTTGTGGTTTTCTCTCAATAATAAGTGAACCAATTTCAAATGTGATCACAAAGTTTGGAAAGCTTTTATTCACAGAGG TTGGGTAGTGTTGGGAGGGGAGTTTAATTACTCAGATTGGCCTGTTATTTGATTTCCTCCTTTGGGAAAAGAATTATGTAGATACCACAT GGAGACAGGGAAACAATTGTGGTAAAACTGTGGATCCTGTTGCTATTTGCCCAGTGAGAAAACAGATTCTGGTATTTGATTTGGTTTTTC TCTTTGTTTCCAGAATGGATGAAAGTCCATGAACCTCCTAAGTTATAATTTAAATTTGTTTGGGGCAAGGTGATTTTATAGTCGAGACAG AGCCCTAGGTCCTTCCTGCCCCATCACTCACTTACGACATCACTTCCATTGTGTGCATGTTTGTTATAGAGGAGGTTTTAGGCTACAATA TTTGTTTAACCTCCCTAAGAACTTTCAAGGCATCTGTCCTGAAAGCTGTTAATTTATGGTCTAGCAGATTTATATTATATGCAGATAATA ATTAACTGGGGATAAAAGAATGGCAAGGGGTGACACAAAGTAGCAAACTGAATACTTCTCCAATAGCAACCCCAAGCTACCTCCTCACCC TGCATCTTGGAGGGAGGCAGGAAATTTCTTTTGAAATAAAGTGCTGGAGCTGAATTCTGCATTATTTATCGTTGCTGCTGAAACCACCTA TAAAAGACTTGCTGGCTAATGTGCATTGTCATATAATGTACACTGTCACATCTTTACAGTCTTGTATGTTATAGAATACAAAATAAGTTG ATGGTTTTGTTTGGTGTGAGCTTTTTGTTTGTTTGTTTAGTTTTGCCTTCATAGGTTATATGCCAAGATAGTATTTGATAAGTCAATGAC ATTTGGATGTTTTCTTCAAAGAATTTTATTTGACCCAGATTTCTTATAAAGTTATCTTACATTAAGGATGTCATTTTCATCAGACCTTCT TTCTACATATTATTCATGAAGCATAATGTTGCATTTCTCCAAATTTTATGCCTGAAAGGGTAGTGTTGCTTCCTAAGGTATCATGTTGTC TTTGTGCTTTGTCCATCTCTTCCGTGGCGAAGCTTTATATCTGTTCCTAAAACAGTTAATCCTGTGAAATAAATATTGAACATAATCCAG AAGAATCTCTCTGTTTCCCTTGGGGAATGCCATATTTAATTCACCAGCAGTAATCCTTTAATAACTGGCAGAGCACTTTATTCTTCTGGT GAGCTCCCTGAATATTTATTTTTCTGATTATAAATTTTCTATATTAGTAGCATTTTTTAATTATTACTTCTTCACTATAGAGCATTTACT TTTAGTCTCTAGATGTATATTTTGGAATGCTGTACTTGGCATAACATAGATTAAAATCATAATGCATGACTAAAAACTCCTTGGATTTAT TTCCCATTTTAAAATTTTTAGCGGTAAGTTCAGATTTATAATCTTTCTCTAGACTTCCATGGTCTGAATGTTGCCTGCTGAAGTAGCAAC CTAAAAAGTATCCCCTGCTTATGCTTGTCCAGTTGGCCCTCCATGTCCATAGGCTTCGCATCTGTGATTCAGCCCACTGTGGGTCAAAAA TATTTGGGGAAAAAAATGGATGGTTGCGCCTTTGCTGAACATGTACAAACTTTTTTTTGTCATTAAACAATATAGTATAACAACTATTTA CAAAGCATTTACATTGTATTAGCTATTATAGGTAATCTAGAGATGATTTAAAGTGTATGGTAGGATGTGCATAGGTTATATGCAAATACT ACACCATTTTCTATAAGGGACTTGAACATCATGGACTTTAGTATCCTAGGGGGTTCTTGGAACCCATCACCCATAGGGGCACCATAGGAC AACTATAGTACCGTGTTTATTTCCTATTAATTCAGGTTCCGTTTAGAGTCTAAAACTAAAACCTAATCATTTAGTCACAGTGTAAAAACA AATGGAAATAACAGCTCAAATCTTCAAAATATTACTATAGCATTATGTTTAAAATAATCTACAACAAAAATGTACCATTTTCAAGCAGTA CTACATTAGGAGCCCTTTTATAGAAAATAATTTCTTCTTTACCCCCGTTCCAGTGTGAATCTAGTATTCTGTTAACATTTGTGTGGCATT TGGAGTTTGTCATCCCCATTGAAGGGAGAGCCTTCTCAGACATGAAGCAAGGGAAACATACTGAATAGTTTTACACAAATTTGATCTGGC TTCCATTTGTCCCCCTCATTTCCCAAATGTTTAAATGTATTGGATTTGGATTCTCAATGTATAAGTTGCCTTATCTGTTAATGTCTATCT TCTGTCTCTTTAATTTTGTATATCTGCTGTTTTGCTTTTGGATACATTTTCTAATTAGAAGTCACATGATAAATATAATCAGTATAGTAA >In-frame_ITGB5_ENST00000296181_chr3_124578089_-_PDLIM5_ENST00000542407_chr4_95507559_+_1685nt GCGGAGCCAGCCCCTCCCCTACCCGGAGCAGCCCGCTGGGGCCGTCCCGAGCGGCGACACACTAGGAGTCCCGGCCGGCCAGCCAGGGCA GCCGCGGTCCCGGGACTCGGCCGTGAGTGCTGCGGGACGGATGGTGGCGGCGGGGCGCGGGCCAGCGCGGGCGCCGTGAGCCGGAGCTGC GCGCGGGGCATGCGGCTGCGGCCCCCGGCCCTCGGCCCCCGCGCTCCGGCCCCAGCCCCGGCCGCCGGCCCCCGCGGAGTGCAGCGACCG CGCCGCCGCTGAGGGAGGCGCCCCACCATGCCGCGGGCCCCGGCGCCGCTGTACGCCTGCCTCCTGGGGCTCTGCGCGCTCCTGCCCCGG CTCGCAGGTCTCAACATATGCACTAGTGGAAGTGCCACCTCATGTGAAGAATGTCTGCTAATCCACCCAAAATGTGCCTGGTGCTCCAAA GAGGACTTCGGAAGCCCACGGTCCATCACCTCTCGGTGTGATCTGAGGGCAAACCTTGTCAAAAATGGCTGTGGAGGTGAGATAGAGAGC CCAGCCAGCAGCTTCCATGTCCTGAGGAGCCTGCCCCTCAGCAGCAAGGGTTCGGGCTCTGCAGGCTGGGACGTCATTCAGATGACACCA CAGGAGATTGCCGTGAACCTCCGGCCCGTGAAAGAATCTGAAGCCGATAATACAAAGAAGGCAAATAACTCTCAGGAGCCTTCTCCGCAG TTGGCTTCCTCGGTAGCTTCCACACGGAGCATGCCCGAGAGCCTGGACAGCCCAACCTCTGGCAGACCAGGGGTTACCAGCCTCACAGCT GCAGCTGCCTTCAAGCCTGTAGGATCCACTGGCGTCATCAAGTCACCAAGCTGGCAACGGCCAAACCAAGGAGTACCTTCCACTGGAAGA ATCTCAAACAGCGCTACTTACTCAGGATCAGTGGCACCAGCCAACTCAGCTTTGGGACAAACCCAGCCAAGTGACCAGGACACTTTAGTG CAAAGAGCTGAGCACATTCCAGCAGGGAAACGAACTCCGATGTGCGCCCATTGTAACCAGGTCATCAGAGGACCATTCTTAGTGGCACTG GGGAAATCTTGGCACCCAGAAGAATTCAACTGCGCTCACTGCAAAAATACAATGGCCTACATTGGATTTGTAGAGGAGAAAGGAGCCCTG TATTGTGAGCTGTGCTATGAGAAATTCTTTGCCCCTGAATGTGGTCGATGCCAAAGGAAGATCCTTGGAGAAGTCATCAGTGCGTTGAAA CAAACTTGGCATGTTTCCTGTTTTGTGTGTGTAGCCTGTGGAAAGCCCATTCGGAACAATGTTTTTCACTTGGAGGATGGTGAACCCTAC TGTGAGACTGATTATTATGCCCTCTTTGGTACTATATGCCATGGATGTGAATTTCCCATAGAAGCTGGTGACATGTTCCTGGAAGCTCTG GGCTACACCTGGCATGACACTTGCTTTGTATGCTCAGTGTGTTGTGAAAGTTTGGAAGGTCAGACCTTTTTCTCCAAGAAGGACAAGCCC CTGTGTAAGAAACATGCTCATTCTGTGAATTTTTGAAAGTCAACAGTTCAGGAGAAGAGAAGGAATTTGAAGAGAAAAAGGAAAATTAAA >In-frame_ITGB5_ENST00000296181_chr3_124578089_-_PDLIM5_ENST00000508216_chr4_95507559_+_1834nt GCGGAGCCAGCCCCTCCCCTACCCGGAGCAGCCCGCTGGGGCCGTCCCGAGCGGCGACACACTAGGAGTCCCGGCCGGCCAGCCAGGGCA GCCGCGGTCCCGGGACTCGGCCGTGAGTGCTGCGGGACGGATGGTGGCGGCGGGGCGCGGGCCAGCGCGGGCGCCGTGAGCCGGAGCTGC GCGCGGGGCATGCGGCTGCGGCCCCCGGCCCTCGGCCCCCGCGCTCCGGCCCCAGCCCCGGCCGCCGGCCCCCGCGGAGTGCAGCGACCG CGCCGCCGCTGAGGGAGGCGCCCCACCATGCCGCGGGCCCCGGCGCCGCTGTACGCCTGCCTCCTGGGGCTCTGCGCGCTCCTGCCCCGG CTCGCAGGTCTCAACATATGCACTAGTGGAAGTGCCACCTCATGTGAAGAATGTCTGCTAATCCACCCAAAATGTGCCTGGTGCTCCAAA GAGGACTTCGGAAGCCCACGGTCCATCACCTCTCGGTGTGATCTGAGGGCAAACCTTGTCAAAAATGGCTGTGGAGGTGAGATAGAGAGC CCAGCCAGCAGCTTCCATGTCCTGAGGAGCCTGCCCCTCAGCAGCAAGGGTTCGGGCTCTGCAGGCTGGGACGTCATTCAGATGACACCA CAGGAGATTGCCGTGAACCTCCGGCCCGTGAAAGAATCTGAAGCCGATAATACAAAGAAGGCAAAGGAAAAGATACCCCTTCACGTCTTT AGTCCCAAATACACAAAATTACGTGACTGGCACCATGAAGTTTCAGCACGTGCTCTTAACGTACAGTGATTTATGAGCCTTGCCCCCCAA GCAGCCAGCACATACCTTTTCATTTACTTTTTTTTTTTCAACTTCATAGCAAAATCTGTATTAAATTTGCCTTATGAAAAAATAGAACTT TTTCTATACTTTTCTAACAATTTCCTATTGTTGTGAGAAAAGGAAGATGAACATGTTTTGTGCTAGTTGGTAGCTCACAAATGTAAAACC AAAAAAAAAAAAAAATAGAAAATTAAGGGACTAGATCTATTTGTGGATTTGTATCTGTTTTTGTTGTGATTAGGGTAGTAATCTTGGAAA ACGAATTATTTTCATAAGTTGAATTTGGTTAGTTGGTTGGTTGAAGCAGAGGATAATGAGCAAATAAAGTCCTTGTCTAATTTGGAAAAT ACTTTCTTTATATTATTAACATCTCCCAAGATTACTTTTTAAGTTCATTATTATGTTACATTCAAAGTTGATTGTAAATTATTCTAAATA AGTAAATATAAGGAGGCAAGAATAAACAAAGACTTTATTAAAGAAGAGTGCGTGCATTGTAGATTTAGGTATCTTTTAAAGTAGGTACTA TTCAGGATGGCTCTATGAAGAGGAGGAGGTCCAGATTTGGCTCCTGAAAAAGGAAAGAAGAGAATTTTACCCCTATTTGCAATGGAGAAA TACAGTATTCTTTGGTTTGGTTGGATTTGCAAATCCTATTTCCTATCAAAGGAAATATCTCTAGTGGATATTTTTAGAATATAGACAATT TCTAGGTATTAACTAATAAGATATGGAAAAGATAGCTTTGCTTTTTTTAATCAGAAGAACATAAAATAAATTACAATATGAATGATTGTG AGACATCAGAGAAATATTTTACTTAGTGACGTAAACTACTGTGCACTGCTGCTATTCCTAGGAAGCTGTGTTTTGGGCAATACATGGAAG CTAAATATATGACCAGAAATGCTTTCTGCCTTGTAATATAGTGTATTATATATTAGAGCTAAATTTAGTAATAAATGCATTTTGAAGTTT >In-frame_ITGB5_ENST00000296181_chr3_124578089_-_PDLIM5_ENST00000514743_chr4_95507559_+_3396nt GCGGAGCCAGCCCCTCCCCTACCCGGAGCAGCCCGCTGGGGCCGTCCCGAGCGGCGACACACTAGGAGTCCCGGCCGGCCAGCCAGGGCA GCCGCGGTCCCGGGACTCGGCCGTGAGTGCTGCGGGACGGATGGTGGCGGCGGGGCGCGGGCCAGCGCGGGCGCCGTGAGCCGGAGCTGC GCGCGGGGCATGCGGCTGCGGCCCCCGGCCCTCGGCCCCCGCGCTCCGGCCCCAGCCCCGGCCGCCGGCCCCCGCGGAGTGCAGCGACCG CGCCGCCGCTGAGGGAGGCGCCCCACCATGCCGCGGGCCCCGGCGCCGCTGTACGCCTGCCTCCTGGGGCTCTGCGCGCTCCTGCCCCGG CTCGCAGGTCTCAACATATGCACTAGTGGAAGTGCCACCTCATGTGAAGAATGTCTGCTAATCCACCCAAAATGTGCCTGGTGCTCCAAA GAGGACTTCGGAAGCCCACGGTCCATCACCTCTCGGTGTGATCTGAGGGCAAACCTTGTCAAAAATGGCTGTGGAGGTGAGATAGAGAGC CCAGCCAGCAGCTTCCATGTCCTGAGGAGCCTGCCCCTCAGCAGCAAGGGTTCGGGCTCTGCAGGCTGGGACGTCATTCAGATGACACCA CAGGAGATTGCCGTGAACCTCCGGCCCGTGAAAGAATCTGAAGCCGATAATACAAAGAAGGCAAAGTTTGACAGTGCTCTGGAAGACCTA CCTAAGAGTGGACCTCACCCTCCTGCAACTCCTCAGGTGTTAACTATTGGTAGCCAAGTGGCCACACTTTCTAAAGTAGCAACTACTTAT TCTAGTTTAAGCAGCTCCACAGGAAATGTGGAAGATTCTTTCGAAGGTTTTCGAAACTTTTCTACCTTCTCTTCTCCTGCTAGATATAGT GCTGCAGTTCTGAGCAGCGCAGCTGCTACTGTGTCTGCTGTTATTGCTACAAAAACCAGGCTCTACACTCCTGAAAGATATCACTCACTC CTGGATGCACTTTGCATCAGCCCTGTCTCCAAGCCTTTAGCTTTTTCCTATCTGCAGTCCTCAAGGAAATCAACTGGCTCTATCCATGTT AAGAAAACAAGTAACTCTCAGGAGCCTTCTCCGCAGTTGGCTTCCTCGGTAGCTTCCACACGGAGCATGCCCGAGAGCCTGGACAGCCCA ACCTCTGGCAGACCAGGGGTTACCAGCCTCACAGCTGCAGCTGCCTTCAAGCCTGTAGGATCCACTGGCGTCATCAAGTCACCAAGCTGG CAACGGCCAAACCAAGGAGTACCTTCCACTGGAAGAATCTCAAACAGCGCTACTTACTCAGGATCAGTGGCACCAGCCAACTCAGCTTTG GGACAAACCCAGCCAAGTGACCAGGACACTTTAGTGCAAAGAGCTGAGCACATTCCAGCAGGGAAACGAACTCCGATGTGCGCCCATTGT AACCAGGTCATCAGAGGACCATTCTTAGTGGCACTGGGGAAATCTTGGCACCCAGAAGAATTCAACTGCGCTCACTGCAAAAATACAATG GCCTACATTGGATTTGTAGAGGAGAAAGGAGCCCTGTATTGTGAGCTGTGCTATGAGAAATTCTTTGCCCCTGAATGTGGTCGATGCCAA AGGAAGATCCTTGGAGAAGTCATCAGTGCGTTGAAACAAACTTGGCATGTTTCCTGTTTTGTGTGTGTAGCCTGTGGAAAGCCCATTCGG AACAATGTTTTTCACTTGGAGGATGGTGAACCCTACTGTGAGACTGATTATTATGCCCTCTTTGGTACTATATGCCATGGATGTGAATTT CCCATAGAAGCTGGTGACATGTTCCTGGAAGCTCTGGGCTACACCTGGCATGACACTTGCTTTGTATGCTCAGTGTGTTGTGAAAGTTTG GAAGGTCAGACCTTTTTCTCCAAGAAGGACAAGCCCCTGTGTAAGAAACATGCTCATTCTGTGAATTTTTGAAAGTCAACAGTTCAGGAG AAGAGAAGGAATTTGAAGAGAAAAAGGAAAATTAAAATTACTAATTAATTTTTAGATTCAATATTTATATGGAGTTTTGAAAAATAATAG TGGCCCTGAAGGAATAAATTCCAGCTTTAAAAACCAAGTCTGAGGAAATATTTGGCTTCATAAAGTAAAGAGACGGTTTGGCATTTATTA TTACTTTTTCCTGTATTTTATGCCCATAAAATAAGCTTTATAAAAACCAATTTCCTGATGGACTATTAAATTCATCTTAGAATAAATTAG TGAAGAATTTAATTTTAGAATAAATAATCCAATCTGAAATAATTATACCTTCTTTCCTTGTTAGGTAGTTATGAGTAAATCTGCAAAAGG CAATGAAAATGCCTTAAATTTTATCAATAACAGAATTATTGTATTTAAAAAAAAACTAATACTTATCTTTAAAATAGTAAATAGGATTTT AAACAGAGAATTTTATCAGTAATAGGTGTCAGTTTTTAAAAAATTGCTTGTAGGCTGAGCGCGGTGGCTCACGCCTGTAATCCCAGCACT TTGGGAGGCCAAGGTGGGTGGACCACATGAGGTCAGGAGTTTGAGATCAGCCTGGCCAACATGGTGAAACCCCATCTCTACTAAAAATAC AAAAATTAGCCGGACGCAGTGGCACGCGCCTGTAATCCCAGCTACTCAAGAGGCTGAGGCACGAGAATCACTTGAACCCGGGAGGGAGAG GTTGCAGTGAGCCAAGATCGTACCACTGCACTCCAGCCTGGGTGACAGAGTGAGACTCTGTCTCCAAAAAAAAACTTTGCTTGTATATTA TTTTTGCCTTACAGTGGATCATTCTAGTAGGAAAGGACAATAAGATTTTTTATCAAAATGTGTCATGCCAGTAAGAGATGTTATATTCTT TTCTCATTTCTTCCCCACCCAAAAATAAGCTACCATATAGCTTATAAGTCTCAAATTTTTGCCTTTTACTAAAATGTGATTGTTTCTATT CATTGTGTATGCTTCATCACCTATATTAGGCAAATTCCATTTTTTTCCCTTGTGCTAAGGTAAAGATTTAATTAAATAATTTTGGCCTCT CATAGTTTTCTCTCTCTTTAAAGAGAATAAATAGAGGGCCAGGTGTGGTGGCTCACGCCTGTGATCCCAGCACTTTGGGAGGCCAAGACG GGCGGATCATGAGGTCAAGAGATCAAGATCATCCTGGCCAACATGGTGAAACCCTGTCTCTACTAAAAATACAAAAATGAGCTGGGCATG GTGGGGCGTGCCTGTAGTCCCATGTACTTGGGAGGCTGAGGCAGGAAAATTCTTGAACCCAGGAGACGGAAGTTGCAGTGAGCTGAGATC |
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FusionGenePPI for ITGB5_PDLIM5 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| ITGB5 | ANXA5, PTK2, CYR61, PAK4, ITGB3BP, ITGA3, PPARD, MERTK, MYC, PDIA3, ALB, SNTA1, EWSR1, SRSF9, EPHA2, EHMT2, MTUS2, KRT40, KRTAP10-9, KRTAP10-8, NOTCH2NL, ITGA5, ATP1B3, KLK5, MFGE8, EDIL3, SPP1, ZBTB17, PLP1, ADAM9, VTN, ST8SIA4, ADAM21, ADAM33, PRG3, ST8SIA3, INSL5, LRRC4, ITGAV | PDLIM5 | TRIM39, CACNA1B, PRKCB, PRKCE, GFI1B, NDUFA7, SIN3A, ELMSAN1, DSTN, FN1, CALU, EIF4A3, METTL1, NPLOC4, PDE12, ANP32A, CBS, IPO11, PKM, PLIN3, SRP14, UBA2, RAD23B, TPD52, ZYX, COIL, CCDC136, KRT40, KRTAP10-7, SUZ12, RNF2, BMI1, SIRT6, ILK, METTL6, RWDD2B, SYT11, DNAJC8, MAP2K1, MAP2K2, ARFIP2, CAMK2G, NTRK1, BTRC, MED4, SSX2IP, CEP128, CEP19, XPO1, CDH1, PDLIM7, TULP3, PHF19, NFATC2IP, DENR, TPM2, EMILIN1, ATG14, G3BP1, BRCA1, TES |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for ITGB5_PDLIM5 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for ITGB5_PDLIM5 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | ITGB5 | C0040128 | Thyroid Diseases | 1 | CTD_human |
| Hgene | ITGB5 | C3495559 | Juvenile arthritis | 1 | CTD_human |
| Tgene | PDLIM5 | C0005586 | Bipolar Disorder | 5 | PSYGENET |
| Tgene | PDLIM5 | C0036341 | Schizophrenia | 4 | PSYGENET |
| Tgene | PDLIM5 | C0041696 | Unipolar Depression | 4 | PSYGENET |
| Tgene | PDLIM5 | C1269683 | Major Depressive Disorder | 4 | PSYGENET |
| Tgene | PDLIM5 | C0151744 | Myocardial Ischemia | 1 | CTD_human |
| Tgene | PDLIM5 | C0221765 | Chronic schizophrenia | 1 | PSYGENET |
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