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Center for Computational Systems Medicine
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FusionGeneSummary

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FusionProtFeature

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FusionGeneSequence

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FusionGenePPI

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RelatedDiseases

Fusion gene ID: 17853

FusionGeneSummary for ITGAV_FARP2

check button Fusion gene summary
Fusion gene informationFusion gene name: ITGAV_FARP2
Fusion gene ID: 17853
HgeneTgene
Gene symbol

ITGAV

FARP2

Gene ID

3685

9855

Gene nameintegrin subunit alpha VFERM, ARH/RhoGEF and pleckstrin domain protein 2
SynonymsCD51|MSK8|VNRA|VTNRFIR|FRG|PLEKHC3
Cytomap

2q32.1

2q37.3

Type of geneprotein-codingprotein-coding
Descriptionintegrin alpha-Vantigen identified by monoclonal antibody L230integrin alphaVbeta3integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)vitronectin receptor subunit alphaFERM, ARHGEF and pleckstrin domain-containing protein 2FERM domain including RhoGEFFERM, RhoGEF and pleckstrin domain protein 2FERM, RhoGEF and pleckstrin domain-containing protein 2FGD1-related Cdc42-GEFPH domain-containing family C member 3pleckst
Modification date2018052020180519
UniProtAcc

P06756

O94887

Ensembl transtripts involved in fusion geneENST00000261023, ENST00000374907, 
ENST00000433736, ENST00000474571, 
ENST00000264042, ENST00000545004, 
ENST00000373287, ENST00000479427, 
Fusion gene scores* DoF score5 X 4 X 5=1003 X 3 X 3=27
# samples 53
** MAII scorelog2(5/100*10)=-1
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(3/27*10)=0.15200309344505
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: ITGAV [Title/Abstract] AND FARP2 [Title/Abstract] AND fusion [Title/Abstract]

Functional or gene categories assigned by FusionGDB annotationTumor suppressor gene involved fusion gene, in-frame but not retained their domain.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneITGAV

GO:0007155

cell adhesion

10218736

HgeneITGAV

GO:0008284

positive regulation of cell proliferation

19578119

HgeneITGAV

GO:0033627

cell adhesion mediated by integrin

12807887|17158881

HgeneITGAV

GO:0034446

substrate adhesion-dependent cell spreading

24658351

HgeneITGAV

GO:0045785

positive regulation of cell adhesion

10708943

HgeneITGAV

GO:0050764

regulation of phagocytosis

10570297

HgeneITGAV

GO:0070588

calcium ion transmembrane transport

18395422

HgeneITGAV

GO:2000536

negative regulation of entry of bacterium into host cell

10570297

TgeneFARP2

GO:0016322

neuron remodeling

12351724

TgeneFARP2

GO:0016601

Rac protein signal transduction

12351724


check button Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
Data typeSourceCancer typeSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
TCGARVLUSCTCGA-43-2578-01AITGAVchr2

187534541

+FARP2chr2

242429377

+
* LD: Li Ding group's fusion gene list
  RV: Roel Verhaak group's fusion gene list
  ChiTaRs fusion database

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000261023ENST00000264042ITGAVchr2

187534541

+FARP2chr2

242429377

+
5CDS-intronENST00000261023ENST00000545004ITGAVchr2

187534541

+FARP2chr2

242429377

+
5CDS-intronENST00000261023ENST00000373287ITGAVchr2

187534541

+FARP2chr2

242429377

+
5CDS-intronENST00000261023ENST00000479427ITGAVchr2

187534541

+FARP2chr2

242429377

+
In-frameENST00000374907ENST00000264042ITGAVchr2

187534541

+FARP2chr2

242429377

+
5CDS-intronENST00000374907ENST00000545004ITGAVchr2

187534541

+FARP2chr2

242429377

+
5CDS-intronENST00000374907ENST00000373287ITGAVchr2

187534541

+FARP2chr2

242429377

+
5CDS-intronENST00000374907ENST00000479427ITGAVchr2

187534541

+FARP2chr2

242429377

+
In-frameENST00000433736ENST00000264042ITGAVchr2

187534541

+FARP2chr2

242429377

+
5CDS-intronENST00000433736ENST00000545004ITGAVchr2

187534541

+FARP2chr2

242429377

+
5CDS-intronENST00000433736ENST00000373287ITGAVchr2

187534541

+FARP2chr2

242429377

+
5CDS-intronENST00000433736ENST00000479427ITGAVchr2

187534541

+FARP2chr2

242429377

+
3UTR-3CDSENST00000474571ENST00000264042ITGAVchr2

187534541

+FARP2chr2

242429377

+
3UTR-intronENST00000474571ENST00000545004ITGAVchr2

187534541

+FARP2chr2

242429377

+
3UTR-intronENST00000474571ENST00000373287ITGAVchr2

187534541

+FARP2chr2

242429377

+
3UTR-intronENST00000474571ENST00000479427ITGAVchr2

187534541

+FARP2chr2

242429377

+

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FusionProtFeatures for ITGAV_FARP2


check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
ITGAV

P06756

FARP2

O94887

Functions as guanine nucleotide exchange factor thatactivates RAC1. May have relatively low activity. Plays a role inthe response to class 3 semaphorins and remodeling of the actincytoskeleton. Plays a role in TNFSF11-mediated osteoclastdifferentiation, especially in podosome rearrangement andreorganization of the actin cytoskeleton. Regulates the activationof ITGB3, integrin signaling and cell adhesion (By similarity).{ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

.

* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
>>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneITGAVchr2:187534541chr2:242429377ENST00000261023+2630260_2689021049Calcium bindingOntology_term=ECO:0000255
HgeneITGAVchr2:187534541chr2:242429377ENST00000261023+2630314_3229021049Calcium bindingOntology_term=ECO:0000255
HgeneITGAVchr2:187534541chr2:242429377ENST00000261023+2630379_3879021049Calcium bindingOntology_term=ECO:0000255
HgeneITGAVchr2:187534541chr2:242429377ENST00000261023+2630443_4519021049Calcium bindingOntology_term=ECO:0000255
HgeneITGAVchr2:187534541chr2:242429377ENST00000374907+2428260_2688661013Calcium bindingOntology_term=ECO:0000255
HgeneITGAVchr2:187534541chr2:242429377ENST00000374907+2428314_3228661013Calcium bindingOntology_term=ECO:0000255
HgeneITGAVchr2:187534541chr2:242429377ENST00000374907+2428379_3878661013Calcium bindingOntology_term=ECO:0000255
HgeneITGAVchr2:187534541chr2:242429377ENST00000374907+2428443_4518661013Calcium bindingOntology_term=ECO:0000255
HgeneITGAVchr2:187534541chr2:242429377ENST00000433736+2630260_2688561003Calcium bindingOntology_term=ECO:0000255
HgeneITGAVchr2:187534541chr2:242429377ENST00000433736+2630314_3228561003Calcium bindingOntology_term=ECO:0000255
HgeneITGAVchr2:187534541chr2:242429377ENST00000433736+2630379_3878561003Calcium bindingOntology_term=ECO:0000255
HgeneITGAVchr2:187534541chr2:242429377ENST00000433736+2630443_4518561003Calcium bindingOntology_term=ECO:0000255
HgeneITGAVchr2:187534541chr2:242429377ENST00000261023+2630109_1709021049RepeatFG-GAP 2
HgeneITGAVchr2:187534541chr2:242429377ENST00000261023+2630173_2259021049RepeatFG-GAP 3
HgeneITGAVchr2:187534541chr2:242429377ENST00000261023+2630237_2919021049RepeatFG-GAP 4
HgeneITGAVchr2:187534541chr2:242429377ENST00000261023+2630292_3579021049RepeatFG-GAP 5
HgeneITGAVchr2:187534541chr2:242429377ENST00000261023+263032_989021049RepeatFG-GAP 1
HgeneITGAVchr2:187534541chr2:242429377ENST00000261023+2630358_4159021049RepeatFG-GAP 6
HgeneITGAVchr2:187534541chr2:242429377ENST00000261023+2630419_4829021049RepeatFG-GAP 7
HgeneITGAVchr2:187534541chr2:242429377ENST00000374907+2428109_1708661013RepeatFG-GAP 2
HgeneITGAVchr2:187534541chr2:242429377ENST00000374907+2428173_2258661013RepeatFG-GAP 3
HgeneITGAVchr2:187534541chr2:242429377ENST00000374907+2428237_2918661013RepeatFG-GAP 4
HgeneITGAVchr2:187534541chr2:242429377ENST00000374907+2428292_3578661013RepeatFG-GAP 5
HgeneITGAVchr2:187534541chr2:242429377ENST00000374907+242832_988661013RepeatFG-GAP 1
HgeneITGAVchr2:187534541chr2:242429377ENST00000374907+2428358_4158661013RepeatFG-GAP 6
HgeneITGAVchr2:187534541chr2:242429377ENST00000374907+2428419_4828661013RepeatFG-GAP 7
HgeneITGAVchr2:187534541chr2:242429377ENST00000433736+2630109_1708561003RepeatFG-GAP 2
HgeneITGAVchr2:187534541chr2:242429377ENST00000433736+2630173_2258561003RepeatFG-GAP 3
HgeneITGAVchr2:187534541chr2:242429377ENST00000433736+2630237_2918561003RepeatFG-GAP 4
HgeneITGAVchr2:187534541chr2:242429377ENST00000433736+2630292_3578561003RepeatFG-GAP 5
HgeneITGAVchr2:187534541chr2:242429377ENST00000433736+263032_988561003RepeatFG-GAP 1
HgeneITGAVchr2:187534541chr2:242429377ENST00000433736+2630358_4158561003RepeatFG-GAP 6
HgeneITGAVchr2:187534541chr2:242429377ENST00000433736+2630419_4828561003RepeatFG-GAP 7
TgeneFARP2chr2:187534541chr2:242429377ENST00000373287+018425_428-39648Compositional biasNote=Poly-Ser
TgeneFARP2chr2:187534541chr2:242429377ENST00000373287+018453_511-39648Compositional biasNote=Pro-rich
TgeneFARP2chr2:187534541chr2:242429377ENST00000264042+2027929_10268071055DomainPH 2
TgeneFARP2chr2:187534541chr2:242429377ENST00000373287+01844_324-39648DomainFERM
TgeneFARP2chr2:187534541chr2:242429377ENST00000373287+018535_726-39648DomainDH
TgeneFARP2chr2:187534541chr2:242429377ENST00000373287+018755_852-39648DomainPH 1
TgeneFARP2chr2:187534541chr2:242429377ENST00000373287+018929_1026-39648DomainPH 2

- In-frame and not-retained protein feature among the 13 regional features.
>>>>>>>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneITGAVchr2:187534541chr2:242429377ENST00000261023+26301019_10239021049MotifNote=GFFKR motif
HgeneITGAVchr2:187534541chr2:242429377ENST00000374907+24281019_10238661013MotifNote=GFFKR motif
HgeneITGAVchr2:187534541chr2:242429377ENST00000433736+26301019_10238561003MotifNote=GFFKR motif
HgeneITGAVchr2:187534541chr2:242429377ENST00000261023+26301017_10489021049Topological domainCytoplasmic
HgeneITGAVchr2:187534541chr2:242429377ENST00000261023+263031_9929021049Topological domainExtracellular
HgeneITGAVchr2:187534541chr2:242429377ENST00000374907+24281017_10488661013Topological domainCytoplasmic
HgeneITGAVchr2:187534541chr2:242429377ENST00000374907+242831_9928661013Topological domainExtracellular
HgeneITGAVchr2:187534541chr2:242429377ENST00000433736+26301017_10488561003Topological domainCytoplasmic
HgeneITGAVchr2:187534541chr2:242429377ENST00000433736+263031_9928561003Topological domainExtracellular
HgeneITGAVchr2:187534541chr2:242429377ENST00000261023+2630993_10169021049TransmembraneHelical
HgeneITGAVchr2:187534541chr2:242429377ENST00000374907+2428993_10168661013TransmembraneHelical
HgeneITGAVchr2:187534541chr2:242429377ENST00000433736+2630993_10168561003TransmembraneHelical
TgeneFARP2chr2:187534541chr2:242429377ENST00000264042+2027425_4288071055Compositional biasNote=Poly-Ser
TgeneFARP2chr2:187534541chr2:242429377ENST00000264042+2027453_5118071055Compositional biasNote=Pro-rich
TgeneFARP2chr2:187534541chr2:242429377ENST00000264042+202744_3248071055DomainFERM
TgeneFARP2chr2:187534541chr2:242429377ENST00000264042+2027535_7268071055DomainDH
TgeneFARP2chr2:187534541chr2:242429377ENST00000264042+2027755_8528071055DomainPH 1


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FusionGeneSequence for ITGAV_FARP2


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.
>In-frame_ITGAV_ENST00000261023_chr2_187534541_+_FARP2_ENST00000264042_chr2_242429377_+_1150aa
MAFPPRRRLRLGPRGLPLLLSGLLLPLCRAFNLDVDSPAEYSGPEGSYFGFAVDFFVPSASSRMFLLVGAPKANTTQPGIVEGGQVLKCD
WSSTRRCQPIEFDATGNRDYAKDDPLEFKSHQWFGASVRSKQDKILACAPLYHWRTEMKQEREPVGTCFLQDGTKTVEYAPCRSQDIDAD
GQGFCQGGFSIDFTKADRVLLGGPGSFYWQGQLISDQVAEIVSKYDPNVYSIKYNNQLATRTAQAIFDDSYLGYSVAVGDFNGDGIDDFV
SGVPRAARTLGMVYIYDGKNMSSLYNFTGEQMAAYFGFSVAATDINGDDYADVFIGAPLFMDRGSDGKLQEVGQVSVSLQRASGDFQTTK
LNGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRSTGLNAVPSQILEGQWAARSMPPSFGYSMKGATDIDKNGYP
DLIVGAFGVDRAILYRARPVITVNAGLEVYPSILNQDNKTCSLPGTALKVSCFNVRFCLKADGKGVLPRKLNFQVELLLDKLKQKGAIRR
ALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPITIFMEYRLDYRTAADTTGLQPILNQFTPANISRQAHILLDCGEDN
VCKPKLEVSVDSDQKKIYIGDDNPLTLIVKAQNQGEGAYEAELIVSIPLQADFIGVVRNNEALARLSCAFKTENQTRQVVCDLGNPMKAG
TQLLAGLRFSVHQQSEMDTSVKFDLQIQSSNLFDKVSPVVSHKVDLAVLAAVEIRGVSSPDHVFLPIPNWEHKENPETEEDVGPVVQHIY
ELRNNGPSSFSKAMLHLQWPYKYNNNTLLYILHYDIDGPMNCTSDMEINPLRIKISSLQTTEKNDTVAGQGERDHLITKRDLALSEGDIH
TLVEESDNEWSVPHCFTIYAAQKTIVVAASTRLEKEKWMLDLNSAIQAAKSGGDTAPALPGRTVCTRPPRSPNEVSLEQESEDDARGVRS
SLEGHGQHRANTTMHVCWYRNTSVSRADHSAAVENQLSGYLLRKFKNSHGWQKLWVVFTNFCLFFYKTHQDDYPLASLPLLGYSVSIPRE

>In-frame_ITGAV_ENST00000374907_chr2_187534541_+_FARP2_ENST00000264042_chr2_242429377_+_1114aa
MAFPPRRRLRLGPRGLPLLLSGLLLPLCRAFNLDVDSPAEYSGPEGSYFGFAVDFFVPSASSRMFLLVGAPKANTTQPGIVEGGQVLKCD
WSSTRRCQPIEFDATGNRDYAKDDPLEFKSHQWFGASVRSKQDKILACAPLYHWRTEMKQEREPVGTCFLQDGTKTVEYAPCRSRQLISD
QVAEIVSKYDPNVYSIKYNNQLATRTAQAIFDDSYLGYSVAVGDFNGDGIDDFVSGVPRAARTLGMVYIYDGKNMSSLYNFTGEQMAAYF
GFSVAATDINGDDYADVFIGAPLFMDRGSDGKLQEVGQVSVSLQRASGDFQTTKLNGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGG
EDKKGIVYIFNGRSTGLNAVPSQILEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVITVNAGLEVYPSILNQ
DNKTCSLPGTALKVSCFNVRFCLKADGKGVLPRKLNFQVELLLDKLKQKGAIRRALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDES
EFRDKLTPITIFMEYRLDYRTAADTTGLQPILNQFTPANISRQAHILLDCGEDNVCKPKLEVSVDSDQKKIYIGDDNPLTLIVKAQNQGE
GAYEAELIVSIPLQADFIGVVRNNEALARLSCAFKTENQTRQVVCDLGNPMKAGTQLLAGLRFSVHQQSEMDTSVKFDLQIQSSNLFDKV
SPVVSHKVDLAVLAAVEIRGVSSPDHVFLPIPNWEHKENPETEEDVGPVVQHIYELRNNGPSSFSKAMLHLQWPYKYNNNTLLYILHYDI
DGPMNCTSDMEINPLRIKISSLQTTEKNDTVAGQGERDHLITKRDLALSEGDIHTLVEESDNEWSVPHCFTIYAAQKTIVVAASTRLEKE
KWMLDLNSAIQAAKSGGDTAPALPGRTVCTRPPRSPNEVSLEQESEDDARGVRSSLEGHGQHRANTTMHVCWYRNTSVSRADHSAAVENQ
LSGYLLRKFKNSHGWQKLWVVFTNFCLFFYKTHQDDYPLASLPLLGYSVSIPREADGIHKDYVFKLQFKSHVYFFRAESKYTFERWMEVI

>In-frame_ITGAV_ENST00000433736_chr2_187534541_+_FARP2_ENST00000264042_chr2_242429377_+_1104aa
MLLGTLLLILYILMLCRMFLLVGAPKANTTQPGIVEGGQVLKCDWSSTRRCQPIEFDATGNRDYAKDDPLEFKSHQWFGASVRSKQDKIL
ACAPLYHWRTEMKQEREPVGTCFLQDGTKTVEYAPCRSQDIDADGQGFCQGGFSIDFTKADRVLLGGPGSFYWQGQLISDQVAEIVSKYD
PNVYSIKYNNQLATRTAQAIFDDSYLGYSVAVGDFNGDGIDDFVSGVPRAARTLGMVYIYDGKNMSSLYNFTGEQMAAYFGFSVAATDIN
GDDYADVFIGAPLFMDRGSDGKLQEVGQVSVSLQRASGDFQTTKLNGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIF
NGRSTGLNAVPSQILEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVITVNAGLEVYPSILNQDNKTCSLPGT
ALKVSCFNVRFCLKADGKGVLPRKLNFQVELLLDKLKQKGAIRRALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPIT
IFMEYRLDYRTAADTTGLQPILNQFTPANISRQAHILLDCGEDNVCKPKLEVSVDSDQKKIYIGDDNPLTLIVKAQNQGEGAYEAELIVS
IPLQADFIGVVRNNEALARLSCAFKTENQTRQVVCDLGNPMKAGTQLLAGLRFSVHQQSEMDTSVKFDLQIQSSNLFDKVSPVVSHKVDL
AVLAAVEIRGVSSPDHVFLPIPNWEHKENPETEEDVGPVVQHIYELRNNGPSSFSKAMLHLQWPYKYNNNTLLYILHYDIDGPMNCTSDM
EINPLRIKISSLQTTEKNDTVAGQGERDHLITKRDLALSEGDIHTLVEESDNEWSVPHCFTIYAAQKTIVVAASTRLEKEKWMLDLNSAI
QAAKSGGDTAPALPGRTVCTRPPRSPNEVSLEQESEDDARGVRSSLEGHGQHRANTTMHVCWYRNTSVSRADHSAAVENQLSGYLLRKFK
NSHGWQKLWVVFTNFCLFFYKTHQDDYPLASLPLLGYSVSIPREADGIHKDYVFKLQFKSHVYFFRAESKYTFERWMEVIQGASSSAGRA


* Fusion transcript sequences (only coding sequence (CDS) region).
>In-frame_ITGAV_ENST00000261023_chr2_187534541_+_FARP2_ENST00000264042_chr2_242429377_+_3450nt
ATGGCTTTTCCGCCGCGGCGACGGCTGCGCCTCGGTCCCCGCGGCCTCCCGCTTCTTCTCTCGGGACTCCTGCTACCTCTGTGCCGCGCC
TTCAACCTAGACGTGGACAGTCCTGCCGAGTACTCTGGCCCCGAGGGAAGTTACTTCGGCTTCGCCGTGGATTTCTTCGTGCCCAGCGCG
TCTTCCCGGATGTTTCTTCTCGTGGGAGCTCCCAAAGCAAACACCACCCAGCCTGGGATTGTGGAAGGAGGGCAGGTCCTCAAATGTGAC
TGGTCTTCTACCCGCCGGTGCCAGCCAATTGAATTTGATGCAACAGGCAATAGAGATTATGCCAAGGATGATCCATTGGAATTTAAGTCC
CATCAGTGGTTTGGAGCATCTGTGAGGTCGAAACAGGATAAAATTTTGGCCTGTGCCCCATTGTACCATTGGAGAACTGAGATGAAACAG
GAGCGAGAGCCTGTTGGAACATGCTTTCTTCAAGATGGAACAAAGACTGTTGAGTATGCTCCATGTAGATCACAAGATATTGATGCTGAT
GGACAGGGATTTTGTCAAGGAGGATTCAGCATTGATTTTACTAAAGCTGACAGAGTACTTCTTGGTGGTCCTGGTAGCTTTTATTGGCAA
GGTCAGCTTATTTCGGATCAAGTGGCAGAAATCGTATCTAAATACGACCCCAATGTTTACAGCATCAAGTATAATAACCAATTAGCAACT
CGGACTGCACAAGCTATTTTTGATGACAGCTATTTGGGTTATTCTGTGGCTGTCGGAGATTTCAATGGTGATGGCATAGATGACTTTGTT
TCAGGAGTTCCAAGAGCAGCAAGGACTTTGGGAATGGTTTATATTTATGATGGGAAGAACATGTCCTCCTTATACAATTTTACTGGCGAG
CAGATGGCTGCATATTTCGGATTTTCTGTAGCTGCCACTGACATTAATGGAGATGATTATGCAGATGTGTTTATTGGAGCACCTCTCTTC
ATGGATCGTGGCTCTGATGGCAAACTCCAAGAGGTGGGGCAGGTCTCAGTGTCTCTACAGAGAGCTTCAGGAGACTTCCAGACGACAAAG
CTGAATGGATTTGAGGTCTTTGCACGGTTTGGCAGTGCCATAGCTCCTTTGGGAGATCTGGACCAGGATGGTTTCAATGATATTGCAATT
GCTGCTCCATATGGGGGTGAAGATAAAAAAGGAATTGTTTATATCTTCAATGGAAGATCAACAGGCTTGAACGCAGTCCCATCTCAAATC
CTTGAAGGGCAGTGGGCTGCTCGAAGCATGCCACCAAGCTTTGGCTATTCAATGAAAGGAGCCACAGATATAGACAAAAATGGATATCCA
GACTTAATTGTAGGAGCTTTTGGTGTAGATCGAGCTATCTTATACAGGGCCAGACCAGTTATCACTGTAAATGCTGGTCTTGAAGTGTAC
CCTAGCATTTTAAATCAAGACAATAAAACCTGCTCACTGCCTGGAACAGCTCTCAAAGTTTCCTGTTTTAATGTTAGGTTCTGCTTAAAG
GCAGATGGCAAAGGAGTACTTCCCAGGAAACTTAATTTCCAGGTGGAACTTCTTTTGGATAAACTCAAGCAAAAGGGAGCAATTCGACGA
GCACTGTTTCTCTACAGCAGGTCCCCAAGTCACTCCAAGAACATGACTATTTCAAGGGGGGGACTGATGCAGTGTGAGGAATTGATAGCG
TATCTGCGGGATGAATCTGAATTTAGAGACAAACTCACTCCAATTACTATTTTTATGGAATATCGGTTGGATTATAGAACAGCTGCTGAT
ACAACAGGCTTGCAACCCATTCTTAACCAGTTCACGCCTGCTAACATTAGTCGACAGGCTCACATTCTACTTGACTGTGGTGAAGACAAT
GTCTGTAAACCCAAGCTGGAAGTTTCTGTAGATAGTGATCAAAAGAAGATCTATATTGGGGATGACAACCCTCTGACATTGATTGTTAAG
GCTCAGAATCAAGGAGAAGGTGCCTACGAAGCTGAGCTCATCGTTTCCATTCCACTGCAGGCTGATTTCATCGGGGTTGTCCGAAACAAT
GAAGCCTTAGCAAGACTTTCCTGTGCATTTAAGACAGAAAACCAAACTCGCCAGGTGGTATGTGACCTTGGAAACCCAATGAAGGCTGGA
ACTCAACTCTTAGCTGGTCTTCGTTTCAGTGTGCACCAGCAGTCAGAGATGGATACTTCTGTGAAATTTGACTTACAAATCCAAAGCTCA
AATCTATTTGACAAAGTAAGCCCAGTTGTATCTCACAAAGTTGATCTTGCTGTTTTAGCTGCAGTTGAGATAAGAGGAGTCTCGAGTCCT
GATCATGTCTTTCTTCCGATTCCAAACTGGGAGCACAAGGAGAACCCTGAGACTGAAGAAGATGTTGGGCCAGTTGTTCAGCACATCTAT
GAGCTGAGAAACAATGGTCCAAGTTCATTCAGCAAGGCAATGCTCCATCTTCAGTGGCCTTACAAATATAATAATAACACTCTGTTGTAT
ATCCTTCATTATGATATTGATGGACCAATGAACTGCACTTCAGATATGGAGATCAACCCTTTGAGAATTAAGATCTCATCTTTGCAAACA
ACTGAAAAGAATGACACGGTTGCCGGGCAAGGTGAGCGGGACCATCTCATCACTAAGCGGGATCTTGCCCTCAGTGAAGGAGATATTCAC
ACTTTGGTGGAAGAAAGTGATAACGAGTGGTCTGTTCCACACTGTTTCACCATCTACGCGGCTCAGAAAACAATCGTGGTGGCAGCCAGC
ACTCGGCTGGAGAAAGAGAAGTGGATGCTGGACCTGAACTCCGCGATCCAAGCAGCCAAGAGTGGCGGTGACACGGCCCCTGCACTGCCA
GGCCGCACTGTGTGCACTCGTCCCCCCAGATCCCCCAACGAGGTATCTCTGGAGCAGGAGTCAGAAGATGATGCTCGGGGTGTCCGCAGC
TCCCTGGAGGGGCATGGCCAGCACCGGGCCAACACCACAATGCACGTGTGCTGGTACCGGAACACCAGCGTGTCCAGGGCAGACCACAGT
GCAGCTGTCGAGAACCAGCTTTCAGGATATCTGCTAAGAAAGTTCAAAAACAGTCATGGCTGGCAGAAGCTCTGGGTCGTCTTTACCAAC
TTCTGTTTGTTCTTCTACAAAACTCATCAGGATGACTACCCACTGGCCAGCCTCCCGCTGCTGGGCTACAGCGTGAGCATCCCCAGGGAG
GCCGATGGCATACACAAAGACTATGTTTTCAAGCTCCAGTTCAAATCCCACGTCTACTTCTTCCGGGCTGAGAGCAAGTACACATTTGAA
AGGTGGATGGAGGTGATCCAGGGGGCCAGCAGCTCAGCCGGGAGGGCCCCAAGCATCGTGCAGGATGGCCCCCAACCCTCCTCAGGGCTG

>In-frame_ITGAV_ENST00000374907_chr2_187534541_+_FARP2_ENST00000264042_chr2_242429377_+_3342nt
ATGGCTTTTCCGCCGCGGCGACGGCTGCGCCTCGGTCCCCGCGGCCTCCCGCTTCTTCTCTCGGGACTCCTGCTACCTCTGTGCCGCGCC
TTCAACCTAGACGTGGACAGTCCTGCCGAGTACTCTGGCCCCGAGGGAAGTTACTTCGGCTTCGCCGTGGATTTCTTCGTGCCCAGCGCG
TCTTCCCGGATGTTTCTTCTCGTGGGAGCTCCCAAAGCAAACACCACCCAGCCTGGGATTGTGGAAGGAGGGCAGGTCCTCAAATGTGAC
TGGTCTTCTACCCGCCGGTGCCAGCCAATTGAATTTGATGCAACAGGCAATAGAGATTATGCCAAGGATGATCCATTGGAATTTAAGTCC
CATCAGTGGTTTGGAGCATCTGTGAGGTCGAAACAGGATAAAATTTTGGCCTGTGCCCCATTGTACCATTGGAGAACTGAGATGAAACAG
GAGCGAGAGCCTGTTGGAACATGCTTTCTTCAAGATGGAACAAAGACTGTTGAGTATGCTCCATGTAGATCACGTCAGCTTATTTCGGAT
CAAGTGGCAGAAATCGTATCTAAATACGACCCCAATGTTTACAGCATCAAGTATAATAACCAATTAGCAACTCGGACTGCACAAGCTATT
TTTGATGACAGCTATTTGGGTTATTCTGTGGCTGTCGGAGATTTCAATGGTGATGGCATAGATGACTTTGTTTCAGGAGTTCCAAGAGCA
GCAAGGACTTTGGGAATGGTTTATATTTATGATGGGAAGAACATGTCCTCCTTATACAATTTTACTGGCGAGCAGATGGCTGCATATTTC
GGATTTTCTGTAGCTGCCACTGACATTAATGGAGATGATTATGCAGATGTGTTTATTGGAGCACCTCTCTTCATGGATCGTGGCTCTGAT
GGCAAACTCCAAGAGGTGGGGCAGGTCTCAGTGTCTCTACAGAGAGCTTCAGGAGACTTCCAGACGACAAAGCTGAATGGATTTGAGGTC
TTTGCACGGTTTGGCAGTGCCATAGCTCCTTTGGGAGATCTGGACCAGGATGGTTTCAATGATATTGCAATTGCTGCTCCATATGGGGGT
GAAGATAAAAAAGGAATTGTTTATATCTTCAATGGAAGATCAACAGGCTTGAACGCAGTCCCATCTCAAATCCTTGAAGGGCAGTGGGCT
GCTCGAAGCATGCCACCAAGCTTTGGCTATTCAATGAAAGGAGCCACAGATATAGACAAAAATGGATATCCAGACTTAATTGTAGGAGCT
TTTGGTGTAGATCGAGCTATCTTATACAGGGCCAGACCAGTTATCACTGTAAATGCTGGTCTTGAAGTGTACCCTAGCATTTTAAATCAA
GACAATAAAACCTGCTCACTGCCTGGAACAGCTCTCAAAGTTTCCTGTTTTAATGTTAGGTTCTGCTTAAAGGCAGATGGCAAAGGAGTA
CTTCCCAGGAAACTTAATTTCCAGGTGGAACTTCTTTTGGATAAACTCAAGCAAAAGGGAGCAATTCGACGAGCACTGTTTCTCTACAGC
AGGTCCCCAAGTCACTCCAAGAACATGACTATTTCAAGGGGGGGACTGATGCAGTGTGAGGAATTGATAGCGTATCTGCGGGATGAATCT
GAATTTAGAGACAAACTCACTCCAATTACTATTTTTATGGAATATCGGTTGGATTATAGAACAGCTGCTGATACAACAGGCTTGCAACCC
ATTCTTAACCAGTTCACGCCTGCTAACATTAGTCGACAGGCTCACATTCTACTTGACTGTGGTGAAGACAATGTCTGTAAACCCAAGCTG
GAAGTTTCTGTAGATAGTGATCAAAAGAAGATCTATATTGGGGATGACAACCCTCTGACATTGATTGTTAAGGCTCAGAATCAAGGAGAA
GGTGCCTACGAAGCTGAGCTCATCGTTTCCATTCCACTGCAGGCTGATTTCATCGGGGTTGTCCGAAACAATGAAGCCTTAGCAAGACTT
TCCTGTGCATTTAAGACAGAAAACCAAACTCGCCAGGTGGTATGTGACCTTGGAAACCCAATGAAGGCTGGAACTCAACTCTTAGCTGGT
CTTCGTTTCAGTGTGCACCAGCAGTCAGAGATGGATACTTCTGTGAAATTTGACTTACAAATCCAAAGCTCAAATCTATTTGACAAAGTA
AGCCCAGTTGTATCTCACAAAGTTGATCTTGCTGTTTTAGCTGCAGTTGAGATAAGAGGAGTCTCGAGTCCTGATCATGTCTTTCTTCCG
ATTCCAAACTGGGAGCACAAGGAGAACCCTGAGACTGAAGAAGATGTTGGGCCAGTTGTTCAGCACATCTATGAGCTGAGAAACAATGGT
CCAAGTTCATTCAGCAAGGCAATGCTCCATCTTCAGTGGCCTTACAAATATAATAATAACACTCTGTTGTATATCCTTCATTATGATATT
GATGGACCAATGAACTGCACTTCAGATATGGAGATCAACCCTTTGAGAATTAAGATCTCATCTTTGCAAACAACTGAAAAGAATGACACG
GTTGCCGGGCAAGGTGAGCGGGACCATCTCATCACTAAGCGGGATCTTGCCCTCAGTGAAGGAGATATTCACACTTTGGTGGAAGAAAGT
GATAACGAGTGGTCTGTTCCACACTGTTTCACCATCTACGCGGCTCAGAAAACAATCGTGGTGGCAGCCAGCACTCGGCTGGAGAAAGAG
AAGTGGATGCTGGACCTGAACTCCGCGATCCAAGCAGCCAAGAGTGGCGGTGACACGGCCCCTGCACTGCCAGGCCGCACTGTGTGCACT
CGTCCCCCCAGATCCCCCAACGAGGTATCTCTGGAGCAGGAGTCAGAAGATGATGCTCGGGGTGTCCGCAGCTCCCTGGAGGGGCATGGC
CAGCACCGGGCCAACACCACAATGCACGTGTGCTGGTACCGGAACACCAGCGTGTCCAGGGCAGACCACAGTGCAGCTGTCGAGAACCAG
CTTTCAGGATATCTGCTAAGAAAGTTCAAAAACAGTCATGGCTGGCAGAAGCTCTGGGTCGTCTTTACCAACTTCTGTTTGTTCTTCTAC
AAAACTCATCAGGATGACTACCCACTGGCCAGCCTCCCGCTGCTGGGCTACAGCGTGAGCATCCCCAGGGAGGCCGATGGCATACACAAA
GACTATGTTTTCAAGCTCCAGTTCAAATCCCACGTCTACTTCTTCCGGGCTGAGAGCAAGTACACATTTGAAAGGTGGATGGAGGTGATC
CAGGGGGCCAGCAGCTCAGCCGGGAGGGCCCCAAGCATCGTGCAGGATGGCCCCCAACCCTCCTCAGGGCTGGAGGGGATGGTCAGGGGG

>In-frame_ITGAV_ENST00000433736_chr2_187534541_+_FARP2_ENST00000264042_chr2_242429377_+_3312nt
ATGCTCCTAGGCACCCTCCTTCTGATCCTGTACATCTTAATGTTGTGCCGGATGTTTCTTCTCGTGGGAGCTCCCAAAGCAAACACCACC
CAGCCTGGGATTGTGGAAGGAGGGCAGGTCCTCAAATGTGACTGGTCTTCTACCCGCCGGTGCCAGCCAATTGAATTTGATGCAACAGGC
AATAGAGATTATGCCAAGGATGATCCATTGGAATTTAAGTCCCATCAGTGGTTTGGAGCATCTGTGAGGTCGAAACAGGATAAAATTTTG
GCCTGTGCCCCATTGTACCATTGGAGAACTGAGATGAAACAGGAGCGAGAGCCTGTTGGAACATGCTTTCTTCAAGATGGAACAAAGACT
GTTGAGTATGCTCCATGTAGATCACAAGATATTGATGCTGATGGACAGGGATTTTGTCAAGGAGGATTCAGCATTGATTTTACTAAAGCT
GACAGAGTACTTCTTGGTGGTCCTGGTAGCTTTTATTGGCAAGGTCAGCTTATTTCGGATCAAGTGGCAGAAATCGTATCTAAATACGAC
CCCAATGTTTACAGCATCAAGTATAATAACCAATTAGCAACTCGGACTGCACAAGCTATTTTTGATGACAGCTATTTGGGTTATTCTGTG
GCTGTCGGAGATTTCAATGGTGATGGCATAGATGACTTTGTTTCAGGAGTTCCAAGAGCAGCAAGGACTTTGGGAATGGTTTATATTTAT
GATGGGAAGAACATGTCCTCCTTATACAATTTTACTGGCGAGCAGATGGCTGCATATTTCGGATTTTCTGTAGCTGCCACTGACATTAAT
GGAGATGATTATGCAGATGTGTTTATTGGAGCACCTCTCTTCATGGATCGTGGCTCTGATGGCAAACTCCAAGAGGTGGGGCAGGTCTCA
GTGTCTCTACAGAGAGCTTCAGGAGACTTCCAGACGACAAAGCTGAATGGATTTGAGGTCTTTGCACGGTTTGGCAGTGCCATAGCTCCT
TTGGGAGATCTGGACCAGGATGGTTTCAATGATATTGCAATTGCTGCTCCATATGGGGGTGAAGATAAAAAAGGAATTGTTTATATCTTC
AATGGAAGATCAACAGGCTTGAACGCAGTCCCATCTCAAATCCTTGAAGGGCAGTGGGCTGCTCGAAGCATGCCACCAAGCTTTGGCTAT
TCAATGAAAGGAGCCACAGATATAGACAAAAATGGATATCCAGACTTAATTGTAGGAGCTTTTGGTGTAGATCGAGCTATCTTATACAGG
GCCAGACCAGTTATCACTGTAAATGCTGGTCTTGAAGTGTACCCTAGCATTTTAAATCAAGACAATAAAACCTGCTCACTGCCTGGAACA
GCTCTCAAAGTTTCCTGTTTTAATGTTAGGTTCTGCTTAAAGGCAGATGGCAAAGGAGTACTTCCCAGGAAACTTAATTTCCAGGTGGAA
CTTCTTTTGGATAAACTCAAGCAAAAGGGAGCAATTCGACGAGCACTGTTTCTCTACAGCAGGTCCCCAAGTCACTCCAAGAACATGACT
ATTTCAAGGGGGGGACTGATGCAGTGTGAGGAATTGATAGCGTATCTGCGGGATGAATCTGAATTTAGAGACAAACTCACTCCAATTACT
ATTTTTATGGAATATCGGTTGGATTATAGAACAGCTGCTGATACAACAGGCTTGCAACCCATTCTTAACCAGTTCACGCCTGCTAACATT
AGTCGACAGGCTCACATTCTACTTGACTGTGGTGAAGACAATGTCTGTAAACCCAAGCTGGAAGTTTCTGTAGATAGTGATCAAAAGAAG
ATCTATATTGGGGATGACAACCCTCTGACATTGATTGTTAAGGCTCAGAATCAAGGAGAAGGTGCCTACGAAGCTGAGCTCATCGTTTCC
ATTCCACTGCAGGCTGATTTCATCGGGGTTGTCCGAAACAATGAAGCCTTAGCAAGACTTTCCTGTGCATTTAAGACAGAAAACCAAACT
CGCCAGGTGGTATGTGACCTTGGAAACCCAATGAAGGCTGGAACTCAACTCTTAGCTGGTCTTCGTTTCAGTGTGCACCAGCAGTCAGAG
ATGGATACTTCTGTGAAATTTGACTTACAAATCCAAAGCTCAAATCTATTTGACAAAGTAAGCCCAGTTGTATCTCACAAAGTTGATCTT
GCTGTTTTAGCTGCAGTTGAGATAAGAGGAGTCTCGAGTCCTGATCATGTCTTTCTTCCGATTCCAAACTGGGAGCACAAGGAGAACCCT
GAGACTGAAGAAGATGTTGGGCCAGTTGTTCAGCACATCTATGAGCTGAGAAACAATGGTCCAAGTTCATTCAGCAAGGCAATGCTCCAT
CTTCAGTGGCCTTACAAATATAATAATAACACTCTGTTGTATATCCTTCATTATGATATTGATGGACCAATGAACTGCACTTCAGATATG
GAGATCAACCCTTTGAGAATTAAGATCTCATCTTTGCAAACAACTGAAAAGAATGACACGGTTGCCGGGCAAGGTGAGCGGGACCATCTC
ATCACTAAGCGGGATCTTGCCCTCAGTGAAGGAGATATTCACACTTTGGTGGAAGAAAGTGATAACGAGTGGTCTGTTCCACACTGTTTC
ACCATCTACGCGGCTCAGAAAACAATCGTGGTGGCAGCCAGCACTCGGCTGGAGAAAGAGAAGTGGATGCTGGACCTGAACTCCGCGATC
CAAGCAGCCAAGAGTGGCGGTGACACGGCCCCTGCACTGCCAGGCCGCACTGTGTGCACTCGTCCCCCCAGATCCCCCAACGAGGTATCT
CTGGAGCAGGAGTCAGAAGATGATGCTCGGGGTGTCCGCAGCTCCCTGGAGGGGCATGGCCAGCACCGGGCCAACACCACAATGCACGTG
TGCTGGTACCGGAACACCAGCGTGTCCAGGGCAGACCACAGTGCAGCTGTCGAGAACCAGCTTTCAGGATATCTGCTAAGAAAGTTCAAA
AACAGTCATGGCTGGCAGAAGCTCTGGGTCGTCTTTACCAACTTCTGTTTGTTCTTCTACAAAACTCATCAGGATGACTACCCACTGGCC
AGCCTCCCGCTGCTGGGCTACAGCGTGAGCATCCCCAGGGAGGCCGATGGCATACACAAAGACTATGTTTTCAAGCTCCAGTTCAAATCC
CACGTCTACTTCTTCCGGGCTGAGAGCAAGTACACATTTGAAAGGTGGATGGAGGTGATCCAGGGGGCCAGCAGCTCAGCCGGGAGGGCC


* Fusion transcript sequences (Full-length transcript).
>In-frame_ITGAV_ENST00000261023_chr2_187534541_+_FARP2_ENST00000264042_chr2_242429377_+_4440nt
CCTCAGACGCTGCGTGGAGCGGCGGAGCCGGAGGGAAGCAAAGGACCGTCTGCGCTGCTGTCCCCGCCCCGCGCGCTCTGCGCCCCTCGT
CCCTGGCGGTCGCTCCGAAGCTCAGCCCTCTTGCCTGCCCCGGAGCTGTCCCGGGCTAGCCGAGAAGAGAGCGGCCGGCAAGTTTGGGCG
CGCGCAGGCGGCGGGCCGCGGGCACTGGGCGCCTCGCTGGGGCGGGGGGAGGTGGCTACCGCTCCCGGCTTGGCGTCCCGCGCGCACTTC
GGCGATGGCTTTTCCGCCGCGGCGACGGCTGCGCCTCGGTCCCCGCGGCCTCCCGCTTCTTCTCTCGGGACTCCTGCTACCTCTGTGCCG
CGCCTTCAACCTAGACGTGGACAGTCCTGCCGAGTACTCTGGCCCCGAGGGAAGTTACTTCGGCTTCGCCGTGGATTTCTTCGTGCCCAG
CGCGTCTTCCCGGATGTTTCTTCTCGTGGGAGCTCCCAAAGCAAACACCACCCAGCCTGGGATTGTGGAAGGAGGGCAGGTCCTCAAATG
TGACTGGTCTTCTACCCGCCGGTGCCAGCCAATTGAATTTGATGCAACAGGCAATAGAGATTATGCCAAGGATGATCCATTGGAATTTAA
GTCCCATCAGTGGTTTGGAGCATCTGTGAGGTCGAAACAGGATAAAATTTTGGCCTGTGCCCCATTGTACCATTGGAGAACTGAGATGAA
ACAGGAGCGAGAGCCTGTTGGAACATGCTTTCTTCAAGATGGAACAAAGACTGTTGAGTATGCTCCATGTAGATCACAAGATATTGATGC
TGATGGACAGGGATTTTGTCAAGGAGGATTCAGCATTGATTTTACTAAAGCTGACAGAGTACTTCTTGGTGGTCCTGGTAGCTTTTATTG
GCAAGGTCAGCTTATTTCGGATCAAGTGGCAGAAATCGTATCTAAATACGACCCCAATGTTTACAGCATCAAGTATAATAACCAATTAGC
AACTCGGACTGCACAAGCTATTTTTGATGACAGCTATTTGGGTTATTCTGTGGCTGTCGGAGATTTCAATGGTGATGGCATAGATGACTT
TGTTTCAGGAGTTCCAAGAGCAGCAAGGACTTTGGGAATGGTTTATATTTATGATGGGAAGAACATGTCCTCCTTATACAATTTTACTGG
CGAGCAGATGGCTGCATATTTCGGATTTTCTGTAGCTGCCACTGACATTAATGGAGATGATTATGCAGATGTGTTTATTGGAGCACCTCT
CTTCATGGATCGTGGCTCTGATGGCAAACTCCAAGAGGTGGGGCAGGTCTCAGTGTCTCTACAGAGAGCTTCAGGAGACTTCCAGACGAC
AAAGCTGAATGGATTTGAGGTCTTTGCACGGTTTGGCAGTGCCATAGCTCCTTTGGGAGATCTGGACCAGGATGGTTTCAATGATATTGC
AATTGCTGCTCCATATGGGGGTGAAGATAAAAAAGGAATTGTTTATATCTTCAATGGAAGATCAACAGGCTTGAACGCAGTCCCATCTCA
AATCCTTGAAGGGCAGTGGGCTGCTCGAAGCATGCCACCAAGCTTTGGCTATTCAATGAAAGGAGCCACAGATATAGACAAAAATGGATA
TCCAGACTTAATTGTAGGAGCTTTTGGTGTAGATCGAGCTATCTTATACAGGGCCAGACCAGTTATCACTGTAAATGCTGGTCTTGAAGT
GTACCCTAGCATTTTAAATCAAGACAATAAAACCTGCTCACTGCCTGGAACAGCTCTCAAAGTTTCCTGTTTTAATGTTAGGTTCTGCTT
AAAGGCAGATGGCAAAGGAGTACTTCCCAGGAAACTTAATTTCCAGGTGGAACTTCTTTTGGATAAACTCAAGCAAAAGGGAGCAATTCG
ACGAGCACTGTTTCTCTACAGCAGGTCCCCAAGTCACTCCAAGAACATGACTATTTCAAGGGGGGGACTGATGCAGTGTGAGGAATTGAT
AGCGTATCTGCGGGATGAATCTGAATTTAGAGACAAACTCACTCCAATTACTATTTTTATGGAATATCGGTTGGATTATAGAACAGCTGC
TGATACAACAGGCTTGCAACCCATTCTTAACCAGTTCACGCCTGCTAACATTAGTCGACAGGCTCACATTCTACTTGACTGTGGTGAAGA
CAATGTCTGTAAACCCAAGCTGGAAGTTTCTGTAGATAGTGATCAAAAGAAGATCTATATTGGGGATGACAACCCTCTGACATTGATTGT
TAAGGCTCAGAATCAAGGAGAAGGTGCCTACGAAGCTGAGCTCATCGTTTCCATTCCACTGCAGGCTGATTTCATCGGGGTTGTCCGAAA
CAATGAAGCCTTAGCAAGACTTTCCTGTGCATTTAAGACAGAAAACCAAACTCGCCAGGTGGTATGTGACCTTGGAAACCCAATGAAGGC
TGGAACTCAACTCTTAGCTGGTCTTCGTTTCAGTGTGCACCAGCAGTCAGAGATGGATACTTCTGTGAAATTTGACTTACAAATCCAAAG
CTCAAATCTATTTGACAAAGTAAGCCCAGTTGTATCTCACAAAGTTGATCTTGCTGTTTTAGCTGCAGTTGAGATAAGAGGAGTCTCGAG
TCCTGATCATGTCTTTCTTCCGATTCCAAACTGGGAGCACAAGGAGAACCCTGAGACTGAAGAAGATGTTGGGCCAGTTGTTCAGCACAT
CTATGAGCTGAGAAACAATGGTCCAAGTTCATTCAGCAAGGCAATGCTCCATCTTCAGTGGCCTTACAAATATAATAATAACACTCTGTT
GTATATCCTTCATTATGATATTGATGGACCAATGAACTGCACTTCAGATATGGAGATCAACCCTTTGAGAATTAAGATCTCATCTTTGCA
AACAACTGAAAAGAATGACACGGTTGCCGGGCAAGGTGAGCGGGACCATCTCATCACTAAGCGGGATCTTGCCCTCAGTGAAGGAGATAT
TCACACTTTGGTGGAAGAAAGTGATAACGAGTGGTCTGTTCCACACTGTTTCACCATCTACGCGGCTCAGAAAACAATCGTGGTGGCAGC
CAGCACTCGGCTGGAGAAAGAGAAGTGGATGCTGGACCTGAACTCCGCGATCCAAGCAGCCAAGAGTGGCGGTGACACGGCCCCTGCACT
GCCAGGCCGCACTGTGTGCACTCGTCCCCCCAGATCCCCCAACGAGGTATCTCTGGAGCAGGAGTCAGAAGATGATGCTCGGGGTGTCCG
CAGCTCCCTGGAGGGGCATGGCCAGCACCGGGCCAACACCACAATGCACGTGTGCTGGTACCGGAACACCAGCGTGTCCAGGGCAGACCA
CAGTGCAGCTGTCGAGAACCAGCTTTCAGGATATCTGCTAAGAAAGTTCAAAAACAGTCATGGCTGGCAGAAGCTCTGGGTCGTCTTTAC
CAACTTCTGTTTGTTCTTCTACAAAACTCATCAGGATGACTACCCACTGGCCAGCCTCCCGCTGCTGGGCTACAGCGTGAGCATCCCCAG
GGAGGCCGATGGCATACACAAAGACTATGTTTTCAAGCTCCAGTTCAAATCCCACGTCTACTTCTTCCGGGCTGAGAGCAAGTACACATT
TGAAAGGTGGATGGAGGTGATCCAGGGGGCCAGCAGCTCAGCCGGGAGGGCCCCAAGCATCGTGCAGGATGGCCCCCAACCCTCCTCAGG
GCTGGAGGGGATGGTCAGGGGGAAGGAGGAATGACGCTCAACCTGCCCAGGTTTGGACACAACTACAAAGAACAGCAGGACACAGAGGTG
ACCTCTGTCCTGAGGCTTCTCAACAGATGGGAAGTGGCTGTGGTCTCACTGGATCCCCACTGGCACCAGCAGTGTGGGTGGGCCTCATGT
AACATCTGGGAGGGGCTTCATCCCCCCACCCAGGACCTAGTGCATGCCAGCAGCTATCTGGGGCCCTGGGAAAAATGTGCGAGTCTTGAG
CGCGGAGCCGCTCAAGCCACAGCTCCCAGGCCCCTGGCTCAAAGACGCAGACAAGGCCTGAGCAGTGCTCTCGGCATCGGACCAAAGCCT
GGGCACACCCTGCCTCTCTCCCCAGAGCAGGGTCCCTGCCGAGGACTGGCCTAGAGCAAGCACTGGAAAAGAGGCCCTGCCATACACCCT
GCGTACCCACTGCCAGGACCCTCTCAGACAAGCGTGGCACAGCCATGCTGACCTTCCATCTGGTGAACCAAGTGGCAGCCCCAGGGGCCT
GCCCTGCAGGTCACAGCTAAACAAGTCTGGCAGAAGCCACGCTTGTTCCCCATGTACCTCTAGAGAAGCAGAAACCAAAGTCCCCCTGTG
CCCTGGGAGGGTGGGGCCGTCTAATTTATTACTGCCCAGCATTCCTTCCAACGGGAAGTAGATGGGCGACTGCTTTGTTCACACACATTT

>In-frame_ITGAV_ENST00000374907_chr2_187534541_+_FARP2_ENST00000264042_chr2_242429377_+_4317nt
GGAGCGGCGGAGCCGGAGGGAAGCAAAGGACCGTCTGCGCTGCTGTCCCCGCCCCGCGCGCTCTGCGCCCCTCGTCCCTGGCGGTCGCTC
CGAAGCTCAGCCCTCTTGCCTGCCCCGGAGCTGTCCCGGGCTAGCCGAGAAGAGAGCGGCCGGCAAGTTTGGGCGCGCGCAGGCGGCGGG
CCGCGGGCACTGGGCGCCTCGCTGGGGCGGGGGGAGGTGGCTACCGCTCCCGGCTTGGCGTCCCGCGCGCACTTCGGCGATGGCTTTTCC
GCCGCGGCGACGGCTGCGCCTCGGTCCCCGCGGCCTCCCGCTTCTTCTCTCGGGACTCCTGCTACCTCTGTGCCGCGCCTTCAACCTAGA
CGTGGACAGTCCTGCCGAGTACTCTGGCCCCGAGGGAAGTTACTTCGGCTTCGCCGTGGATTTCTTCGTGCCCAGCGCGTCTTCCCGGAT
GTTTCTTCTCGTGGGAGCTCCCAAAGCAAACACCACCCAGCCTGGGATTGTGGAAGGAGGGCAGGTCCTCAAATGTGACTGGTCTTCTAC
CCGCCGGTGCCAGCCAATTGAATTTGATGCAACAGGCAATAGAGATTATGCCAAGGATGATCCATTGGAATTTAAGTCCCATCAGTGGTT
TGGAGCATCTGTGAGGTCGAAACAGGATAAAATTTTGGCCTGTGCCCCATTGTACCATTGGAGAACTGAGATGAAACAGGAGCGAGAGCC
TGTTGGAACATGCTTTCTTCAAGATGGAACAAAGACTGTTGAGTATGCTCCATGTAGATCACGTCAGCTTATTTCGGATCAAGTGGCAGA
AATCGTATCTAAATACGACCCCAATGTTTACAGCATCAAGTATAATAACCAATTAGCAACTCGGACTGCACAAGCTATTTTTGATGACAG
CTATTTGGGTTATTCTGTGGCTGTCGGAGATTTCAATGGTGATGGCATAGATGACTTTGTTTCAGGAGTTCCAAGAGCAGCAAGGACTTT
GGGAATGGTTTATATTTATGATGGGAAGAACATGTCCTCCTTATACAATTTTACTGGCGAGCAGATGGCTGCATATTTCGGATTTTCTGT
AGCTGCCACTGACATTAATGGAGATGATTATGCAGATGTGTTTATTGGAGCACCTCTCTTCATGGATCGTGGCTCTGATGGCAAACTCCA
AGAGGTGGGGCAGGTCTCAGTGTCTCTACAGAGAGCTTCAGGAGACTTCCAGACGACAAAGCTGAATGGATTTGAGGTCTTTGCACGGTT
TGGCAGTGCCATAGCTCCTTTGGGAGATCTGGACCAGGATGGTTTCAATGATATTGCAATTGCTGCTCCATATGGGGGTGAAGATAAAAA
AGGAATTGTTTATATCTTCAATGGAAGATCAACAGGCTTGAACGCAGTCCCATCTCAAATCCTTGAAGGGCAGTGGGCTGCTCGAAGCAT
GCCACCAAGCTTTGGCTATTCAATGAAAGGAGCCACAGATATAGACAAAAATGGATATCCAGACTTAATTGTAGGAGCTTTTGGTGTAGA
TCGAGCTATCTTATACAGGGCCAGACCAGTTATCACTGTAAATGCTGGTCTTGAAGTGTACCCTAGCATTTTAAATCAAGACAATAAAAC
CTGCTCACTGCCTGGAACAGCTCTCAAAGTTTCCTGTTTTAATGTTAGGTTCTGCTTAAAGGCAGATGGCAAAGGAGTACTTCCCAGGAA
ACTTAATTTCCAGGTGGAACTTCTTTTGGATAAACTCAAGCAAAAGGGAGCAATTCGACGAGCACTGTTTCTCTACAGCAGGTCCCCAAG
TCACTCCAAGAACATGACTATTTCAAGGGGGGGACTGATGCAGTGTGAGGAATTGATAGCGTATCTGCGGGATGAATCTGAATTTAGAGA
CAAACTCACTCCAATTACTATTTTTATGGAATATCGGTTGGATTATAGAACAGCTGCTGATACAACAGGCTTGCAACCCATTCTTAACCA
GTTCACGCCTGCTAACATTAGTCGACAGGCTCACATTCTACTTGACTGTGGTGAAGACAATGTCTGTAAACCCAAGCTGGAAGTTTCTGT
AGATAGTGATCAAAAGAAGATCTATATTGGGGATGACAACCCTCTGACATTGATTGTTAAGGCTCAGAATCAAGGAGAAGGTGCCTACGA
AGCTGAGCTCATCGTTTCCATTCCACTGCAGGCTGATTTCATCGGGGTTGTCCGAAACAATGAAGCCTTAGCAAGACTTTCCTGTGCATT
TAAGACAGAAAACCAAACTCGCCAGGTGGTATGTGACCTTGGAAACCCAATGAAGGCTGGAACTCAACTCTTAGCTGGTCTTCGTTTCAG
TGTGCACCAGCAGTCAGAGATGGATACTTCTGTGAAATTTGACTTACAAATCCAAAGCTCAAATCTATTTGACAAAGTAAGCCCAGTTGT
ATCTCACAAAGTTGATCTTGCTGTTTTAGCTGCAGTTGAGATAAGAGGAGTCTCGAGTCCTGATCATGTCTTTCTTCCGATTCCAAACTG
GGAGCACAAGGAGAACCCTGAGACTGAAGAAGATGTTGGGCCAGTTGTTCAGCACATCTATGAGCTGAGAAACAATGGTCCAAGTTCATT
CAGCAAGGCAATGCTCCATCTTCAGTGGCCTTACAAATATAATAATAACACTCTGTTGTATATCCTTCATTATGATATTGATGGACCAAT
GAACTGCACTTCAGATATGGAGATCAACCCTTTGAGAATTAAGATCTCATCTTTGCAAACAACTGAAAAGAATGACACGGTTGCCGGGCA
AGGTGAGCGGGACCATCTCATCACTAAGCGGGATCTTGCCCTCAGTGAAGGAGATATTCACACTTTGGTGGAAGAAAGTGATAACGAGTG
GTCTGTTCCACACTGTTTCACCATCTACGCGGCTCAGAAAACAATCGTGGTGGCAGCCAGCACTCGGCTGGAGAAAGAGAAGTGGATGCT
GGACCTGAACTCCGCGATCCAAGCAGCCAAGAGTGGCGGTGACACGGCCCCTGCACTGCCAGGCCGCACTGTGTGCACTCGTCCCCCCAG
ATCCCCCAACGAGGTATCTCTGGAGCAGGAGTCAGAAGATGATGCTCGGGGTGTCCGCAGCTCCCTGGAGGGGCATGGCCAGCACCGGGC
CAACACCACAATGCACGTGTGCTGGTACCGGAACACCAGCGTGTCCAGGGCAGACCACAGTGCAGCTGTCGAGAACCAGCTTTCAGGATA
TCTGCTAAGAAAGTTCAAAAACAGTCATGGCTGGCAGAAGCTCTGGGTCGTCTTTACCAACTTCTGTTTGTTCTTCTACAAAACTCATCA
GGATGACTACCCACTGGCCAGCCTCCCGCTGCTGGGCTACAGCGTGAGCATCCCCAGGGAGGCCGATGGCATACACAAAGACTATGTTTT
CAAGCTCCAGTTCAAATCCCACGTCTACTTCTTCCGGGCTGAGAGCAAGTACACATTTGAAAGGTGGATGGAGGTGATCCAGGGGGCCAG
CAGCTCAGCCGGGAGGGCCCCAAGCATCGTGCAGGATGGCCCCCAACCCTCCTCAGGGCTGGAGGGGATGGTCAGGGGGAAGGAGGAATG
ACGCTCAACCTGCCCAGGTTTGGACACAACTACAAAGAACAGCAGGACACAGAGGTGACCTCTGTCCTGAGGCTTCTCAACAGATGGGAA
GTGGCTGTGGTCTCACTGGATCCCCACTGGCACCAGCAGTGTGGGTGGGCCTCATGTAACATCTGGGAGGGGCTTCATCCCCCCACCCAG
GACCTAGTGCATGCCAGCAGCTATCTGGGGCCCTGGGAAAAATGTGCGAGTCTTGAGCGCGGAGCCGCTCAAGCCACAGCTCCCAGGCCC
CTGGCTCAAAGACGCAGACAAGGCCTGAGCAGTGCTCTCGGCATCGGACCAAAGCCTGGGCACACCCTGCCTCTCTCCCCAGAGCAGGGT
CCCTGCCGAGGACTGGCCTAGAGCAAGCACTGGAAAAGAGGCCCTGCCATACACCCTGCGTACCCACTGCCAGGACCCTCTCAGACAAGC
GTGGCACAGCCATGCTGACCTTCCATCTGGTGAACCAAGTGGCAGCCCCAGGGGCCTGCCCTGCAGGTCACAGCTAAACAAGTCTGGCAG
AAGCCACGCTTGTTCCCCATGTACCTCTAGAGAAGCAGAAACCAAAGTCCCCCTGTGCCCTGGGAGGGTGGGGCCGTCTAATTTATTACT

>In-frame_ITGAV_ENST00000433736_chr2_187534541_+_FARP2_ENST00000264042_chr2_242429377_+_4158nt
CTTTGTAGCTCCTGGAGATTCAATTCTTTCTTGCCAGGGTCTTTCTACCTCTGCCTCACATATTCCCTCCATCTCTTCATTCCACTTCCC
TCATCCCCACCCCCCACTCCCCTCCATCCTCAATACACAAATGCTCCTAGGCACCCTCCTTCTGATCCTGTACATCTTAATGTTGTGCCG
GATGTTTCTTCTCGTGGGAGCTCCCAAAGCAAACACCACCCAGCCTGGGATTGTGGAAGGAGGGCAGGTCCTCAAATGTGACTGGTCTTC
TACCCGCCGGTGCCAGCCAATTGAATTTGATGCAACAGGCAATAGAGATTATGCCAAGGATGATCCATTGGAATTTAAGTCCCATCAGTG
GTTTGGAGCATCTGTGAGGTCGAAACAGGATAAAATTTTGGCCTGTGCCCCATTGTACCATTGGAGAACTGAGATGAAACAGGAGCGAGA
GCCTGTTGGAACATGCTTTCTTCAAGATGGAACAAAGACTGTTGAGTATGCTCCATGTAGATCACAAGATATTGATGCTGATGGACAGGG
ATTTTGTCAAGGAGGATTCAGCATTGATTTTACTAAAGCTGACAGAGTACTTCTTGGTGGTCCTGGTAGCTTTTATTGGCAAGGTCAGCT
TATTTCGGATCAAGTGGCAGAAATCGTATCTAAATACGACCCCAATGTTTACAGCATCAAGTATAATAACCAATTAGCAACTCGGACTGC
ACAAGCTATTTTTGATGACAGCTATTTGGGTTATTCTGTGGCTGTCGGAGATTTCAATGGTGATGGCATAGATGACTTTGTTTCAGGAGT
TCCAAGAGCAGCAAGGACTTTGGGAATGGTTTATATTTATGATGGGAAGAACATGTCCTCCTTATACAATTTTACTGGCGAGCAGATGGC
TGCATATTTCGGATTTTCTGTAGCTGCCACTGACATTAATGGAGATGATTATGCAGATGTGTTTATTGGAGCACCTCTCTTCATGGATCG
TGGCTCTGATGGCAAACTCCAAGAGGTGGGGCAGGTCTCAGTGTCTCTACAGAGAGCTTCAGGAGACTTCCAGACGACAAAGCTGAATGG
ATTTGAGGTCTTTGCACGGTTTGGCAGTGCCATAGCTCCTTTGGGAGATCTGGACCAGGATGGTTTCAATGATATTGCAATTGCTGCTCC
ATATGGGGGTGAAGATAAAAAAGGAATTGTTTATATCTTCAATGGAAGATCAACAGGCTTGAACGCAGTCCCATCTCAAATCCTTGAAGG
GCAGTGGGCTGCTCGAAGCATGCCACCAAGCTTTGGCTATTCAATGAAAGGAGCCACAGATATAGACAAAAATGGATATCCAGACTTAAT
TGTAGGAGCTTTTGGTGTAGATCGAGCTATCTTATACAGGGCCAGACCAGTTATCACTGTAAATGCTGGTCTTGAAGTGTACCCTAGCAT
TTTAAATCAAGACAATAAAACCTGCTCACTGCCTGGAACAGCTCTCAAAGTTTCCTGTTTTAATGTTAGGTTCTGCTTAAAGGCAGATGG
CAAAGGAGTACTTCCCAGGAAACTTAATTTCCAGGTGGAACTTCTTTTGGATAAACTCAAGCAAAAGGGAGCAATTCGACGAGCACTGTT
TCTCTACAGCAGGTCCCCAAGTCACTCCAAGAACATGACTATTTCAAGGGGGGGACTGATGCAGTGTGAGGAATTGATAGCGTATCTGCG
GGATGAATCTGAATTTAGAGACAAACTCACTCCAATTACTATTTTTATGGAATATCGGTTGGATTATAGAACAGCTGCTGATACAACAGG
CTTGCAACCCATTCTTAACCAGTTCACGCCTGCTAACATTAGTCGACAGGCTCACATTCTACTTGACTGTGGTGAAGACAATGTCTGTAA
ACCCAAGCTGGAAGTTTCTGTAGATAGTGATCAAAAGAAGATCTATATTGGGGATGACAACCCTCTGACATTGATTGTTAAGGCTCAGAA
TCAAGGAGAAGGTGCCTACGAAGCTGAGCTCATCGTTTCCATTCCACTGCAGGCTGATTTCATCGGGGTTGTCCGAAACAATGAAGCCTT
AGCAAGACTTTCCTGTGCATTTAAGACAGAAAACCAAACTCGCCAGGTGGTATGTGACCTTGGAAACCCAATGAAGGCTGGAACTCAACT
CTTAGCTGGTCTTCGTTTCAGTGTGCACCAGCAGTCAGAGATGGATACTTCTGTGAAATTTGACTTACAAATCCAAAGCTCAAATCTATT
TGACAAAGTAAGCCCAGTTGTATCTCACAAAGTTGATCTTGCTGTTTTAGCTGCAGTTGAGATAAGAGGAGTCTCGAGTCCTGATCATGT
CTTTCTTCCGATTCCAAACTGGGAGCACAAGGAGAACCCTGAGACTGAAGAAGATGTTGGGCCAGTTGTTCAGCACATCTATGAGCTGAG
AAACAATGGTCCAAGTTCATTCAGCAAGGCAATGCTCCATCTTCAGTGGCCTTACAAATATAATAATAACACTCTGTTGTATATCCTTCA
TTATGATATTGATGGACCAATGAACTGCACTTCAGATATGGAGATCAACCCTTTGAGAATTAAGATCTCATCTTTGCAAACAACTGAAAA
GAATGACACGGTTGCCGGGCAAGGTGAGCGGGACCATCTCATCACTAAGCGGGATCTTGCCCTCAGTGAAGGAGATATTCACACTTTGGT
GGAAGAAAGTGATAACGAGTGGTCTGTTCCACACTGTTTCACCATCTACGCGGCTCAGAAAACAATCGTGGTGGCAGCCAGCACTCGGCT
GGAGAAAGAGAAGTGGATGCTGGACCTGAACTCCGCGATCCAAGCAGCCAAGAGTGGCGGTGACACGGCCCCTGCACTGCCAGGCCGCAC
TGTGTGCACTCGTCCCCCCAGATCCCCCAACGAGGTATCTCTGGAGCAGGAGTCAGAAGATGATGCTCGGGGTGTCCGCAGCTCCCTGGA
GGGGCATGGCCAGCACCGGGCCAACACCACAATGCACGTGTGCTGGTACCGGAACACCAGCGTGTCCAGGGCAGACCACAGTGCAGCTGT
CGAGAACCAGCTTTCAGGATATCTGCTAAGAAAGTTCAAAAACAGTCATGGCTGGCAGAAGCTCTGGGTCGTCTTTACCAACTTCTGTTT
GTTCTTCTACAAAACTCATCAGGATGACTACCCACTGGCCAGCCTCCCGCTGCTGGGCTACAGCGTGAGCATCCCCAGGGAGGCCGATGG
CATACACAAAGACTATGTTTTCAAGCTCCAGTTCAAATCCCACGTCTACTTCTTCCGGGCTGAGAGCAAGTACACATTTGAAAGGTGGAT
GGAGGTGATCCAGGGGGCCAGCAGCTCAGCCGGGAGGGCCCCAAGCATCGTGCAGGATGGCCCCCAACCCTCCTCAGGGCTGGAGGGGAT
GGTCAGGGGGAAGGAGGAATGACGCTCAACCTGCCCAGGTTTGGACACAACTACAAAGAACAGCAGGACACAGAGGTGACCTCTGTCCTG
AGGCTTCTCAACAGATGGGAAGTGGCTGTGGTCTCACTGGATCCCCACTGGCACCAGCAGTGTGGGTGGGCCTCATGTAACATCTGGGAG
GGGCTTCATCCCCCCACCCAGGACCTAGTGCATGCCAGCAGCTATCTGGGGCCCTGGGAAAAATGTGCGAGTCTTGAGCGCGGAGCCGCT
CAAGCCACAGCTCCCAGGCCCCTGGCTCAAAGACGCAGACAAGGCCTGAGCAGTGCTCTCGGCATCGGACCAAAGCCTGGGCACACCCTG
CCTCTCTCCCCAGAGCAGGGTCCCTGCCGAGGACTGGCCTAGAGCAAGCACTGGAAAAGAGGCCCTGCCATACACCCTGCGTACCCACTG
CCAGGACCCTCTCAGACAAGCGTGGCACAGCCATGCTGACCTTCCATCTGGTGAACCAAGTGGCAGCCCCAGGGGCCTGCCCTGCAGGTC
ACAGCTAAACAAGTCTGGCAGAAGCCACGCTTGTTCCCCATGTACCTCTAGAGAAGCAGAAACCAAAGTCCCCCTGTGCCCTGGGAGGGT
GGGGCCGTCTAATTTATTACTGCCCAGCATTCCTTCCAACGGGAAGTAGATGGGCGACTGCTTTGTTCACACACATTTGATTAAAAATAA


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FusionGenePPI for ITGAV_FARP2


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page

.

check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors
ITGAVNOV, ILK, ITGB3, AUP1, L1CAM, CYR61, PLP1, MMP2, CSF1R, CBL, BCAR1, PHKA2, PXN, FBXO6, MCAT, KRT3, FN1, THBS1, EPHA2, TAZ, SUSD4, DPEP2, NTRK1, ITGB1, PSMD12, SPP1, LGALS3BP, FBXW7, MAPK3, NCOR1, NCOR2, EP300, MAPK1, STAT1, SHC1, PTK2, PLA2G2A, ADAM9, ERBB2, ANGPT2, NCL, PAK4, TNFSF13B, LYZL2, NAAA, DEFA1, ST3GAL1, GGH, TMEM25, ST8SIA4, TCTN2, INSL5, FCGR3B, EDIL3, FUT8, PTCH1, B3GNT2, UBC, ITGA4, ITGAV, ITGB5, AGMAT, TRIM25FARP2PDZK1, UBE2G2, CSNK1E, PTGER3, XPO1, RPS27A, TRIM41, GPR156, CLNS1A, PRMT5, MISP, RIOK1, CHRM3, COPRS, PRKCI, CCDC88A, C17orf85, PRICKLE3, HERC2, TRIM25


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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RelatedDrugs for ITGAV_FARP2


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status
HgeneITGAVP06756DB00098Antithymocyte immunoglobulin (rabbit)Integrin alpha-Vbiotechapproved

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RelatedDiseases for ITGAV_FARP2


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneITGAVC0038454Cerebrovascular accident1CTD_human
HgeneITGAVC2937358Cerebral Hemorrhage1CTD_human
TgeneFARP2C0004352Autistic Disorder1CTD_human
TgeneFARP2C0023434Chronic Lymphocytic Leukemia1CTD_human
TgeneFARP2C2931817Chromosome 2q37 deletion syndrome1CTD_human