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Fusion gene ID: 17813 |
FusionGeneSummary for ITGA2_MYO18B |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: ITGA2_MYO18B | Fusion gene ID: 17813 | Hgene | Tgene | Gene symbol | ITGA2 | MYO18B | Gene ID | 3673 | 84700 |
| Gene name | integrin subunit alpha 2 | myosin XVIIIB | |
| Synonyms | BR|CD49B|GPIa|HPA-5|VLA-2|VLAA2 | KFS4 | |
| Cytomap | 5q11.2 | 22q12.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | integrin alpha-2CD49 antigen-like family member Balpha 2 subunit of VLA-2 receptorcollagen receptorhuman platelet alloantigen system 5integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)platelet antigen Brplatelet glycoprotein GPIaplatelet | unconventional myosin-XVIIIbmyosin 18B | |
| Modification date | 20180527 | 20180519 | |
| UniProtAcc | P17301 | Q8IUG5 | |
| Ensembl transtripts involved in fusion gene | ENST00000296585, | ENST00000536101, ENST00000335473, ENST00000407587, ENST00000536204, | |
| Fusion gene scores | * DoF score | 8 X 5 X 5=200 | 6 X 5 X 6=180 |
| # samples | 8 | 6 | |
| ** MAII score | log2(8/200*10)=-1.32192809488736 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(6/180*10)=-1.58496250072116 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: ITGA2 [Title/Abstract] AND MYO18B [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | KIRP | TCGA-P4-A5EB-01A | ITGA2 | chr5 | 52353931 | + | MYO18B | chr22 | 26388329 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000296585 | ENST00000536101 | ITGA2 | chr5 | 52353931 | + | MYO18B | chr22 | 26388329 | + |
| In-frame | ENST00000296585 | ENST00000335473 | ITGA2 | chr5 | 52353931 | + | MYO18B | chr22 | 26388329 | + |
| In-frame | ENST00000296585 | ENST00000407587 | ITGA2 | chr5 | 52353931 | + | MYO18B | chr22 | 26388329 | + |
| 5CDS-intron | ENST00000296585 | ENST00000536204 | ITGA2 | chr5 | 52353931 | + | MYO18B | chr22 | 26388329 | + |
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FusionProtFeatures for ITGA2_MYO18B |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| ITGA2 | MYO18B |
| Integrin alpha-2/beta-1 is a receptor for laminin,collagen, collagen C-propeptides, fibronectin and E-cadherin. Itrecognizes the proline-hydroxylated sequence G-F-P-G-E-R incollagen. It is responsible for adhesion of platelets and othercells to collagens, modulation of collagen and collagenase geneexpression, force generation and organization of newly synthesizedextracellular matrix. (Microbial infection) Integrin ITGA2:ITGB1 acts as areceptor for Human rotavirus A. {ECO:0000269|PubMed:12941907}. (Microbial infection) Integrin ITGA2:ITGB1 acts as areceptor for Human echoviruses 1 and 8.{ECO:0000269|PubMed:8411387}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | ITGA2 | chr5:52353931 | chr22:26388329 | ENST00000296585 | + | 10 | 30 | 188_365 | 391 | 1182 | Domain | VWFA |
| Hgene | ITGA2 | chr5:52353931 | chr22:26388329 | ENST00000296585 | + | 10 | 30 | 101_161 | 391 | 1182 | Repeat | FG-GAP 2 |
| Hgene | ITGA2 | chr5:52353931 | chr22:26388329 | ENST00000296585 | + | 10 | 30 | 34_92 | 391 | 1182 | Repeat | FG-GAP 1 |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >ITGA2 | chr5:52353931 | chr22:26388329 | ENST00000296585 | + | 10 | 30 | 499_507 | 391 | 1182 | Calcium binding | Ontology_term=ECO:0000255 |
| Hgene | >ITGA2 | chr5:52353931 | chr22:26388329 | ENST00000296585 | + | 10 | 30 | 563_571 | 391 | 1182 | Calcium binding | Ontology_term=ECO:0000255 |
| Hgene | >ITGA2 | chr5:52353931 | chr22:26388329 | ENST00000296585 | + | 10 | 30 | 627_635 | 391 | 1182 | Calcium binding | Ontology_term=ECO:0000255 |
| Hgene | >ITGA2 | chr5:52353931 | chr22:26388329 | ENST00000296585 | + | 10 | 30 | 1157_1161 | 391 | 1182 | Motif | Note=GFFKR motif |
| Hgene | >ITGA2 | chr5:52353931 | chr22:26388329 | ENST00000296585 | + | 10 | 30 | 366_420 | 391 | 1182 | Repeat | FG-GAP 3 |
| Hgene | >ITGA2 | chr5:52353931 | chr22:26388329 | ENST00000296585 | + | 10 | 30 | 423_475 | 391 | 1182 | Repeat | FG-GAP 4 |
| Hgene | >ITGA2 | chr5:52353931 | chr22:26388329 | ENST00000296585 | + | 10 | 30 | 477_539 | 391 | 1182 | Repeat | FG-GAP 5 |
| Hgene | >ITGA2 | chr5:52353931 | chr22:26388329 | ENST00000296585 | + | 10 | 30 | 540_598 | 391 | 1182 | Repeat | FG-GAP 6 |
| Hgene | >ITGA2 | chr5:52353931 | chr22:26388329 | ENST00000296585 | + | 10 | 30 | 602_664 | 391 | 1182 | Repeat | FG-GAP 7 |
| Hgene | >ITGA2 | chr5:52353931 | chr22:26388329 | ENST00000296585 | + | 10 | 30 | 1155_1181 | 391 | 1182 | Topological domain | Cytoplasmic |
| Hgene | >ITGA2 | chr5:52353931 | chr22:26388329 | ENST00000296585 | + | 10 | 30 | 30_1132 | 391 | 1182 | Topological domain | Extracellular |
| Hgene | >ITGA2 | chr5:52353931 | chr22:26388329 | ENST00000296585 | + | 10 | 30 | 1133_1154 | 391 | 1182 | Transmembrane | Helical |
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FusionGeneSequence for ITGA2_MYO18B |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_ITGA2_ENST00000296585_chr5_52353931_+_MYO18B_ENST00000536101_chr22_26388329_+_907aa MGPERTGAAPLPLLLVLALSQGILNCCLAYNVGLPEAKIFSGPSSEQFGYAVQQFINPKGNWLLVGSPWSGFPENRMGDVYKCPVDLSTA TCEKLNLQTSTSIPNVTEMKTNMSLGLILTRNMGTGGFLTCGPLWAQQCGNQYYTTGVCSDISPDFQLSASFSPATQPCPSLIDVVVVCD ESNSIYPWDAVKNFLEKFVQGLDIGPTKTQVGLIQYANNPRVVFNLNTYKTKEEMIVATSQTSQYGGDLTNTFGAIQYARKYAYSAASGG RRSATKVMVVVTDGESHDGSMLKAVIDQCNHDNILRFGIAVLGYLNRNALDTKNLIKEIKAIASIPTERYFFNVSDEAALLEKAGTLGEQ IFSIEGTVQGGDNFQMEMSQVGFSADYSSQNEKYVEELAAVRQTLQTDLETSIRRIADLQAALEEVASSDSDTESVQTAVDCGSSGRKEM DNVSILSSQPEGSLQSWLSCTLSLATDTMRTPSRQSATSSRILSPRINEEAGDTERTQSALALSRARSTNVHSKTSGDKPVSPHFVRRQK YCHFGDGEVLAVQRKSTERLEPASSPLASRSTNTSPLSREKLPSPSAALSEFVEGLRRKRAQRGQGSTLGLEDWPTLPIYQTTGASTLRR GRAGSDEGNLSLRVGAKSPLEIEGAAGGLLRSTSLKCISSDGVGGTTLLPEKSKTQFSSCESLLESRPSMGRKLSSPTTPRDMLLSPTLR PRRRCLESSVDDAGCPDLGKEPLVFQNRQFAHLMEEPLGSDPFSWKLPSLDYERKTKVDFDDFLPAIRKPQTPTSLAGSAKGGQDGSQRS SIHFETEEANRSFLSGIKTILKKSPEPKEDPAHLSDSSSSSGSIVSFKSADSIKSRPGIPRLAGDGGERTSPERREPGTGRKDDDVASIM >In-frame_ITGA2_ENST00000296585_chr5_52353931_+_MYO18B_ENST00000335473_chr22_26388329_+_907aa MGPERTGAAPLPLLLVLALSQGILNCCLAYNVGLPEAKIFSGPSSEQFGYAVQQFINPKGNWLLVGSPWSGFPENRMGDVYKCPVDLSTA TCEKLNLQTSTSIPNVTEMKTNMSLGLILTRNMGTGGFLTCGPLWAQQCGNQYYTTGVCSDISPDFQLSASFSPATQPCPSLIDVVVVCD ESNSIYPWDAVKNFLEKFVQGLDIGPTKTQVGLIQYANNPRVVFNLNTYKTKEEMIVATSQTSQYGGDLTNTFGAIQYARKYAYSAASGG RRSATKVMVVVTDGESHDGSMLKAVIDQCNHDNILRFGIAVLGYLNRNALDTKNLIKEIKAIASIPTERYFFNVSDEAALLEKAGTLGEQ IFSIEGTVQGGDNFQMEMSQVGFSADYSSQNEKYVEELAAVRQTLQTDLETSIRRIADLQAALEEVASSDSDTESVQTAVDCGSSGRKEM DNVSILSSQPEGSLQSWLSCTLSLATDTMRTPSRQSATSSRILSPRINEEAGDTERTQSALALSRARSTNVHSKTSGDKPVSPHFVRRQK YCHFGDGEVLAVQRKSTERLEPASSPLASRSTNTSPLSREKLPSPSAALSEFVEGLRRKRAQRGQGSTLGLEDWPTLPIYQTTGASTLRR GRAGSDEGNLSLRVGAKSPLEIEGAAGGLLRSTSLKCISSDGVGGTTLLPEKSKTQFSSCESLLESRPSMGRKLSSPTTPRDMLLSPTLR PRRRCLESSVDDAGCPDLGKEPLVFQNRQFAHLMEEPLGSDPFSWKLPSLDYERKTKVDFDDFLPAIRKPQTPTSLAGSAKGGQDGSQRS SIHFETEEANRSFLSGIKTILKKSPEPKEDPAHLSDSSSSSGSIVSFKSADSIKSRPGIPRLAGDGGERTSPERREPGTGRKDDDVASIM >In-frame_ITGA2_ENST00000296585_chr5_52353931_+_MYO18B_ENST00000407587_chr22_26388329_+_907aa MGPERTGAAPLPLLLVLALSQGILNCCLAYNVGLPEAKIFSGPSSEQFGYAVQQFINPKGNWLLVGSPWSGFPENRMGDVYKCPVDLSTA TCEKLNLQTSTSIPNVTEMKTNMSLGLILTRNMGTGGFLTCGPLWAQQCGNQYYTTGVCSDISPDFQLSASFSPATQPCPSLIDVVVVCD ESNSIYPWDAVKNFLEKFVQGLDIGPTKTQVGLIQYANNPRVVFNLNTYKTKEEMIVATSQTSQYGGDLTNTFGAIQYARKYAYSAASGG RRSATKVMVVVTDGESHDGSMLKAVIDQCNHDNILRFGIAVLGYLNRNALDTKNLIKEIKAIASIPTERYFFNVSDEAALLEKAGTLGEQ IFSIEGTVQGGDNFQMEMSQVGFSADYSSQNEKYVEELAAVRQTLQTDLETSIRRIADLQAALEEVASSDSDTESVQTAVDCGSSGRKEM DNVSILSSQPEGSLQSWLSCTLSLATDTMRTPSRQSATSSRILSPRINEEAGDTERTQSALALSRARSTNVHSKTSGDKPVSPHFVRRQK YCHFGDGEVLAVQRKSTERLEPASSPLASRSTNTSPLSREKLPSPSAALSEFVEGLRRKRAQRGQGSTLGLEDWPTLPIYQTTGASTLRR GRAGSDEGNLSLRVGAKSPLEIEGAAGGLLRSTSLKCISSDGVGGTTLLPEKSKTQFSSCESLLESRPSMGRKLSSPTTPRDMLLSPTLR PRRRCLESSVDDAGCPDLGKEPLVFQNRQFAHLMEEPLGSDPFSWKLPSLDYERKTKVDFDDFLPAIRKPQTPTSLAGSAKGGQDGSQRS SIHFETEEANRSFLSGIKTILKKSPEPKEDPAHLSDSSSSSGSIVSFKSADSIKSRPGIPRLAGDGGERTSPERREPGTGRKDDDVASIM |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_ITGA2_ENST00000296585_chr5_52353931_+_MYO18B_ENST00000536101_chr22_26388329_+_2721nt ATGGGGCCAGAACGGACAGGGGCCGCGCCGCTGCCGCTGCTGCTGGTGTTAGCGCTCAGTCAAGGCATTTTAAATTGTTGTTTGGCCTAC AATGTTGGTCTCCCAGAAGCAAAAATATTTTCCGGTCCTTCAAGTGAACAGTTTGGCTATGCAGTGCAGCAGTTTATAAATCCAAAAGGC AACTGGTTACTGGTTGGTTCACCCTGGAGTGGCTTTCCTGAGAACCGAATGGGAGATGTGTATAAATGTCCTGTTGACCTATCCACTGCC ACATGTGAAAAACTAAATTTGCAAACTTCAACAAGCATTCCAAATGTTACTGAGATGAAAACCAACATGAGCCTCGGCTTGATCCTCACC AGGAACATGGGAACTGGAGGTTTTCTCACATGTGGTCCTCTGTGGGCACAGCAATGTGGGAATCAGTATTACACAACGGGTGTGTGTTCT GACATCAGTCCTGATTTTCAGCTCTCAGCCAGCTTCTCACCTGCAACTCAGCCCTGCCCTTCCCTCATAGATGTTGTGGTTGTGTGTGAT GAATCAAATAGTATTTATCCTTGGGATGCAGTAAAGAATTTTTTGGAAAAATTTGTACAAGGCCTGGATATAGGCCCCACAAAGACACAG GTGGGGTTAATTCAGTATGCCAATAATCCAAGAGTTGTGTTTAACTTGAACACATATAAAACCAAAGAAGAAATGATTGTAGCAACATCC CAGACATCCCAATATGGTGGGGACCTCACAAACACATTCGGAGCAATTCAATATGCAAGAAAATATGCTTATTCAGCAGCTTCTGGTGGG CGACGAAGTGCTACGAAAGTAATGGTAGTTGTAACTGACGGTGAATCACATGATGGTTCAATGTTGAAAGCTGTGATTGATCAATGCAAC CATGACAATATACTGAGGTTTGGCATAGCAGTTCTTGGGTACTTAAACAGAAACGCCCTTGATACTAAAAATTTAATAAAAGAAATAAAA GCAATCGCTAGTATTCCAACAGAAAGATACTTTTTCAATGTGTCTGATGAAGCAGCTCTACTAGAAAAGGCTGGGACATTAGGAGAACAA ATTTTCAGCATTGAAGGTACTGTTCAAGGAGGAGACAACTTTCAGATGGAAATGTCACAAGTGGGATTCAGTGCAGATTACTCTTCTCAA AATGAGAAGTACGTGGAGGAACTTGCAGCAGTGAGGCAAACCCTCCAGACAGACCTGGAGACATCCATTCGGCGGATTGCCGACCTGCAG GCTGCCTTGGAAGAAGTGGCATCCAGTGACAGTGATACTGAGAGTGTCCAGACGGCAGTGGATTGTGGCAGCAGCGGCCGAAAAGAGATG GATAACGTCTCCATCCTCAGCTCCCAGCCAGAGGGCAGCCTGCAGTCCTGGTTGAGCTGTACTCTGTCCCTGGCCACAGATACTATGAGG ACTCCTTCTCGACAGTCAGCCACCAGCAGCCGCATCCTCAGCCCCAGGATAAACGAAGAGGCTGGGGACACTGAGAGGACCCAGTCGGCA TTGGCACTGAGCAGAGCCCGGTCCACCAATGTCCACAGCAAGACCTCAGGAGACAAGCCTGTTTCTCCCCACTTTGTCCGCCGGCAAAAG TACTGTCATTTTGGGGACGGCGAAGTGCTTGCCGTCCAGAGAAAGTCCACAGAGAGATTAGAACCTGCTTCCTCTCCCCTGGCTTCTCGG AGTACAAATACATCCCCGCTGTCGAGGGAAAAGCTGCCCAGTCCTTCAGCGGCCCTCTCGGAGTTCGTGGAAGGGCTCCGGAGGAAGAGA GCCCAGAGAGGCCAGGGGTCCACGCTGGGCCTAGAGGACTGGCCCACTCTCCCCATTTACCAGACGACTGGGGCCTCCACACTAAGGAGG GGCAGGGCTGGCAGTGACGAGGGAAACCTCTCGCTGAGGGTTGGGGCAAAGTCACCCCTGGAAATCGAAGGGGCCGCTGGTGGTCTCTTG AGGTCCACCAGCCTCAAATGCATCTCTTCAGACGGTGTTGGGGGCACAACCCTACTCCCCGAAAAGTCGAAAACCCAATTCAGTTCCTGC GAGTCCCTCTTAGAATCCAGACCGAGCATGGGGAGAAAACTGAGCTCTCCGACCACACCCAGGGACATGCTGTTGTCGCCCACACTGCGT CCTCGGAGGCGGTGTCTGGAGTCCTCTGTGGACGATGCGGGCTGTCCAGACCTTGGAAAGGAGCCGCTTGTTTTCCAGAACCGCCAGTTT GCCCACCTGATGGAGGAACCTCTAGGCAGTGACCCATTCAGCTGGAAACTCCCAAGCCTCGACTACGAACGCAAGACCAAAGTGGACTTC GATGACTTCCTCCCAGCTATCCGGAAGCCCCAGACACCTACCTCCTTGGCTGGATCAGCCAAAGGTGGGCAAGACGGTTCACAGCGTTCA AGCATCCACTTTGAAACGGAAGAGGCTAACCGTTCCTTTCTCTCGGGGATCAAGACCATTTTGAAGAAGAGCCCGGAGCCCAAGGAGGAT CCCGCTCACCTGTCTGACTCGTCCTCATCCTCCGGCTCCATCGTGTCCTTCAAAAGTGCTGACAGCATCAAAAGTCGACCAGGAATCCCA CGACTTGCGGGTGACGGTGGCGAGCGAACGTCCCCCGAGCGGAGAGAGCCAGGGACGGGGAGGAAAGACGACGATGTTGCGAGCATAATG >In-frame_ITGA2_ENST00000296585_chr5_52353931_+_MYO18B_ENST00000335473_chr22_26388329_+_2721nt ATGGGGCCAGAACGGACAGGGGCCGCGCCGCTGCCGCTGCTGCTGGTGTTAGCGCTCAGTCAAGGCATTTTAAATTGTTGTTTGGCCTAC AATGTTGGTCTCCCAGAAGCAAAAATATTTTCCGGTCCTTCAAGTGAACAGTTTGGCTATGCAGTGCAGCAGTTTATAAATCCAAAAGGC AACTGGTTACTGGTTGGTTCACCCTGGAGTGGCTTTCCTGAGAACCGAATGGGAGATGTGTATAAATGTCCTGTTGACCTATCCACTGCC ACATGTGAAAAACTAAATTTGCAAACTTCAACAAGCATTCCAAATGTTACTGAGATGAAAACCAACATGAGCCTCGGCTTGATCCTCACC AGGAACATGGGAACTGGAGGTTTTCTCACATGTGGTCCTCTGTGGGCACAGCAATGTGGGAATCAGTATTACACAACGGGTGTGTGTTCT GACATCAGTCCTGATTTTCAGCTCTCAGCCAGCTTCTCACCTGCAACTCAGCCCTGCCCTTCCCTCATAGATGTTGTGGTTGTGTGTGAT GAATCAAATAGTATTTATCCTTGGGATGCAGTAAAGAATTTTTTGGAAAAATTTGTACAAGGCCTGGATATAGGCCCCACAAAGACACAG GTGGGGTTAATTCAGTATGCCAATAATCCAAGAGTTGTGTTTAACTTGAACACATATAAAACCAAAGAAGAAATGATTGTAGCAACATCC CAGACATCCCAATATGGTGGGGACCTCACAAACACATTCGGAGCAATTCAATATGCAAGAAAATATGCTTATTCAGCAGCTTCTGGTGGG CGACGAAGTGCTACGAAAGTAATGGTAGTTGTAACTGACGGTGAATCACATGATGGTTCAATGTTGAAAGCTGTGATTGATCAATGCAAC CATGACAATATACTGAGGTTTGGCATAGCAGTTCTTGGGTACTTAAACAGAAACGCCCTTGATACTAAAAATTTAATAAAAGAAATAAAA GCAATCGCTAGTATTCCAACAGAAAGATACTTTTTCAATGTGTCTGATGAAGCAGCTCTACTAGAAAAGGCTGGGACATTAGGAGAACAA ATTTTCAGCATTGAAGGTACTGTTCAAGGAGGAGACAACTTTCAGATGGAAATGTCACAAGTGGGATTCAGTGCAGATTACTCTTCTCAA AATGAGAAGTACGTGGAGGAACTTGCAGCAGTGAGGCAAACCCTCCAGACAGACCTGGAGACATCCATTCGGCGGATTGCCGACCTGCAG GCTGCCTTGGAAGAAGTGGCATCCAGTGACAGTGATACTGAGAGTGTCCAGACGGCAGTGGATTGTGGCAGCAGCGGCCGAAAAGAGATG GATAACGTCTCCATCCTCAGCTCCCAGCCAGAGGGCAGCCTGCAGTCCTGGTTGAGCTGTACTCTGTCCCTGGCCACAGATACTATGAGG ACTCCTTCTCGACAGTCAGCCACCAGCAGCCGCATCCTCAGCCCCAGGATAAACGAAGAGGCTGGGGACACTGAGAGGACCCAGTCGGCA TTGGCACTGAGCAGAGCCCGGTCCACCAATGTCCACAGCAAGACCTCAGGAGACAAGCCTGTTTCTCCCCACTTTGTCCGCCGGCAAAAG TACTGTCATTTTGGGGACGGCGAAGTGCTTGCCGTCCAGAGAAAGTCCACAGAGAGATTAGAACCTGCTTCCTCTCCCCTGGCTTCTCGG AGTACAAATACATCCCCGCTGTCGAGGGAAAAGCTGCCCAGTCCTTCAGCGGCCCTCTCGGAGTTCGTGGAAGGGCTCCGGAGGAAGAGA GCCCAGAGAGGCCAGGGGTCCACGCTGGGCCTAGAGGACTGGCCCACTCTCCCCATTTACCAGACGACTGGGGCCTCCACACTAAGGAGG GGCAGGGCTGGCAGTGACGAGGGAAACCTCTCGCTGAGGGTTGGGGCAAAGTCACCCCTGGAAATCGAAGGGGCCGCTGGTGGTCTCTTG AGGTCCACCAGCCTCAAATGCATCTCTTCAGACGGTGTTGGGGGCACAACCCTACTCCCCGAAAAGTCGAAAACCCAATTCAGTTCCTGC GAGTCCCTCTTAGAATCCAGACCGAGCATGGGGAGAAAACTGAGCTCTCCGACCACACCCAGGGACATGCTGTTGTCGCCCACACTGCGT CCTCGGAGGCGGTGTCTGGAGTCCTCTGTGGACGATGCGGGCTGTCCAGACCTTGGAAAGGAGCCGCTTGTTTTCCAGAACCGCCAGTTT GCCCACCTGATGGAGGAACCTCTAGGCAGTGACCCATTCAGCTGGAAACTCCCAAGCCTCGACTACGAACGCAAGACCAAAGTGGACTTC GATGACTTCCTCCCAGCTATCCGGAAGCCCCAGACACCTACCTCCTTGGCTGGATCAGCCAAAGGTGGGCAAGACGGTTCACAGCGTTCA AGCATCCACTTTGAAACGGAAGAGGCTAACCGTTCCTTTCTCTCGGGGATCAAGACCATTTTGAAGAAGAGCCCGGAGCCCAAGGAGGAT CCCGCTCACCTGTCTGACTCGTCCTCATCCTCCGGCTCCATCGTGTCCTTCAAAAGTGCTGACAGCATCAAAAGTCGACCAGGAATCCCA CGACTTGCGGGTGACGGTGGCGAGCGAACGTCCCCCGAGCGGAGAGAGCCAGGGACGGGGAGGAAAGACGACGATGTTGCGAGCATAATG >In-frame_ITGA2_ENST00000296585_chr5_52353931_+_MYO18B_ENST00000407587_chr22_26388329_+_2721nt ATGGGGCCAGAACGGACAGGGGCCGCGCCGCTGCCGCTGCTGCTGGTGTTAGCGCTCAGTCAAGGCATTTTAAATTGTTGTTTGGCCTAC AATGTTGGTCTCCCAGAAGCAAAAATATTTTCCGGTCCTTCAAGTGAACAGTTTGGCTATGCAGTGCAGCAGTTTATAAATCCAAAAGGC AACTGGTTACTGGTTGGTTCACCCTGGAGTGGCTTTCCTGAGAACCGAATGGGAGATGTGTATAAATGTCCTGTTGACCTATCCACTGCC ACATGTGAAAAACTAAATTTGCAAACTTCAACAAGCATTCCAAATGTTACTGAGATGAAAACCAACATGAGCCTCGGCTTGATCCTCACC AGGAACATGGGAACTGGAGGTTTTCTCACATGTGGTCCTCTGTGGGCACAGCAATGTGGGAATCAGTATTACACAACGGGTGTGTGTTCT GACATCAGTCCTGATTTTCAGCTCTCAGCCAGCTTCTCACCTGCAACTCAGCCCTGCCCTTCCCTCATAGATGTTGTGGTTGTGTGTGAT GAATCAAATAGTATTTATCCTTGGGATGCAGTAAAGAATTTTTTGGAAAAATTTGTACAAGGCCTGGATATAGGCCCCACAAAGACACAG GTGGGGTTAATTCAGTATGCCAATAATCCAAGAGTTGTGTTTAACTTGAACACATATAAAACCAAAGAAGAAATGATTGTAGCAACATCC CAGACATCCCAATATGGTGGGGACCTCACAAACACATTCGGAGCAATTCAATATGCAAGAAAATATGCTTATTCAGCAGCTTCTGGTGGG CGACGAAGTGCTACGAAAGTAATGGTAGTTGTAACTGACGGTGAATCACATGATGGTTCAATGTTGAAAGCTGTGATTGATCAATGCAAC CATGACAATATACTGAGGTTTGGCATAGCAGTTCTTGGGTACTTAAACAGAAACGCCCTTGATACTAAAAATTTAATAAAAGAAATAAAA GCAATCGCTAGTATTCCAACAGAAAGATACTTTTTCAATGTGTCTGATGAAGCAGCTCTACTAGAAAAGGCTGGGACATTAGGAGAACAA ATTTTCAGCATTGAAGGTACTGTTCAAGGAGGAGACAACTTTCAGATGGAAATGTCACAAGTGGGATTCAGTGCAGATTACTCTTCTCAA AATGAGAAGTACGTGGAGGAACTTGCAGCAGTGAGGCAAACCCTCCAGACAGACCTGGAGACATCCATTCGGCGGATTGCCGACCTGCAG GCTGCCTTGGAAGAAGTGGCATCCAGTGACAGTGATACTGAGAGTGTCCAGACGGCAGTGGATTGTGGCAGCAGCGGCCGAAAAGAGATG GATAACGTCTCCATCCTCAGCTCCCAGCCAGAGGGCAGCCTGCAGTCCTGGTTGAGCTGTACTCTGTCCCTGGCCACAGATACTATGAGG ACTCCTTCTCGACAGTCAGCCACCAGCAGCCGCATCCTCAGCCCCAGGATAAACGAAGAGGCTGGGGACACTGAGAGGACCCAGTCGGCA TTGGCACTGAGCAGAGCCCGGTCCACCAATGTCCACAGCAAGACCTCAGGAGACAAGCCTGTTTCTCCCCACTTTGTCCGCCGGCAAAAG TACTGTCATTTTGGGGACGGCGAAGTGCTTGCCGTCCAGAGAAAGTCCACAGAGAGATTAGAACCTGCTTCCTCTCCCCTGGCTTCTCGG AGTACAAATACATCCCCGCTGTCGAGGGAAAAGCTGCCCAGTCCTTCAGCGGCCCTCTCGGAGTTCGTGGAAGGGCTCCGGAGGAAGAGA GCCCAGAGAGGCCAGGGGTCCACGCTGGGCCTAGAGGACTGGCCCACTCTCCCCATTTACCAGACGACTGGGGCCTCCACACTAAGGAGG GGCAGGGCTGGCAGTGACGAGGGAAACCTCTCGCTGAGGGTTGGGGCAAAGTCACCCCTGGAAATCGAAGGGGCCGCTGGTGGTCTCTTG AGGTCCACCAGCCTCAAATGCATCTCTTCAGACGGTGTTGGGGGCACAACCCTACTCCCCGAAAAGTCGAAAACCCAATTCAGTTCCTGC GAGTCCCTCTTAGAATCCAGACCGAGCATGGGGAGAAAACTGAGCTCTCCGACCACACCCAGGGACATGCTGTTGTCGCCCACACTGCGT CCTCGGAGGCGGTGTCTGGAGTCCTCTGTGGACGATGCGGGCTGTCCAGACCTTGGAAAGGAGCCGCTTGTTTTCCAGAACCGCCAGTTT GCCCACCTGATGGAGGAACCTCTAGGCAGTGACCCATTCAGCTGGAAACTCCCAAGCCTCGACTACGAACGCAAGACCAAAGTGGACTTC GATGACTTCCTCCCAGCTATCCGGAAGCCCCAGACACCTACCTCCTTGGCTGGATCAGCCAAAGGTGGGCAAGACGGTTCACAGCGTTCA AGCATCCACTTTGAAACGGAAGAGGCTAACCGTTCCTTTCTCTCGGGGATCAAGACCATTTTGAAGAAGAGCCCGGAGCCCAAGGAGGAT CCCGCTCACCTGTCTGACTCGTCCTCATCCTCCGGCTCCATCGTGTCCTTCAAAAGTGCTGACAGCATCAAAAGTCGACCAGGAATCCCA CGACTTGCGGGTGACGGTGGCGAGCGAACGTCCCCCGAGCGGAGAGAGCCAGGGACGGGGAGGAAAGACGACGATGTTGCGAGCATAATG |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_ITGA2_ENST00000296585_chr5_52353931_+_MYO18B_ENST00000536101_chr22_26388329_+_2952nt TTTTCCCTGCTCTCACCGGGCGGGGGAGAGAAGCCCTCTGGACAGCTTCTAGAGTGTGCAGGTTCTCGTATCCCTCGGCCAAGGGTATCC TCTGCAAACCTCTGCAAACCCAGCGCAACTACGGTCCCCCGGTCAGACCCAGGATGGGGCCAGAACGGACAGGGGCCGCGCCGCTGCCGC TGCTGCTGGTGTTAGCGCTCAGTCAAGGCATTTTAAATTGTTGTTTGGCCTACAATGTTGGTCTCCCAGAAGCAAAAATATTTTCCGGTC CTTCAAGTGAACAGTTTGGCTATGCAGTGCAGCAGTTTATAAATCCAAAAGGCAACTGGTTACTGGTTGGTTCACCCTGGAGTGGCTTTC CTGAGAACCGAATGGGAGATGTGTATAAATGTCCTGTTGACCTATCCACTGCCACATGTGAAAAACTAAATTTGCAAACTTCAACAAGCA TTCCAAATGTTACTGAGATGAAAACCAACATGAGCCTCGGCTTGATCCTCACCAGGAACATGGGAACTGGAGGTTTTCTCACATGTGGTC CTCTGTGGGCACAGCAATGTGGGAATCAGTATTACACAACGGGTGTGTGTTCTGACATCAGTCCTGATTTTCAGCTCTCAGCCAGCTTCT CACCTGCAACTCAGCCCTGCCCTTCCCTCATAGATGTTGTGGTTGTGTGTGATGAATCAAATAGTATTTATCCTTGGGATGCAGTAAAGA ATTTTTTGGAAAAATTTGTACAAGGCCTGGATATAGGCCCCACAAAGACACAGGTGGGGTTAATTCAGTATGCCAATAATCCAAGAGTTG TGTTTAACTTGAACACATATAAAACCAAAGAAGAAATGATTGTAGCAACATCCCAGACATCCCAATATGGTGGGGACCTCACAAACACAT TCGGAGCAATTCAATATGCAAGAAAATATGCTTATTCAGCAGCTTCTGGTGGGCGACGAAGTGCTACGAAAGTAATGGTAGTTGTAACTG ACGGTGAATCACATGATGGTTCAATGTTGAAAGCTGTGATTGATCAATGCAACCATGACAATATACTGAGGTTTGGCATAGCAGTTCTTG GGTACTTAAACAGAAACGCCCTTGATACTAAAAATTTAATAAAAGAAATAAAAGCAATCGCTAGTATTCCAACAGAAAGATACTTTTTCA ATGTGTCTGATGAAGCAGCTCTACTAGAAAAGGCTGGGACATTAGGAGAACAAATTTTCAGCATTGAAGGTACTGTTCAAGGAGGAGACA ACTTTCAGATGGAAATGTCACAAGTGGGATTCAGTGCAGATTACTCTTCTCAAAATGAGAAGTACGTGGAGGAACTTGCAGCAGTGAGGC AAACCCTCCAGACAGACCTGGAGACATCCATTCGGCGGATTGCCGACCTGCAGGCTGCCTTGGAAGAAGTGGCATCCAGTGACAGTGATA CTGAGAGTGTCCAGACGGCAGTGGATTGTGGCAGCAGCGGCCGAAAAGAGATGGATAACGTCTCCATCCTCAGCTCCCAGCCAGAGGGCA GCCTGCAGTCCTGGTTGAGCTGTACTCTGTCCCTGGCCACAGATACTATGAGGACTCCTTCTCGACAGTCAGCCACCAGCAGCCGCATCC TCAGCCCCAGGATAAACGAAGAGGCTGGGGACACTGAGAGGACCCAGTCGGCATTGGCACTGAGCAGAGCCCGGTCCACCAATGTCCACA GCAAGACCTCAGGAGACAAGCCTGTTTCTCCCCACTTTGTCCGCCGGCAAAAGTACTGTCATTTTGGGGACGGCGAAGTGCTTGCCGTCC AGAGAAAGTCCACAGAGAGATTAGAACCTGCTTCCTCTCCCCTGGCTTCTCGGAGTACAAATACATCCCCGCTGTCGAGGGAAAAGCTGC CCAGTCCTTCAGCGGCCCTCTCGGAGTTCGTGGAAGGGCTCCGGAGGAAGAGAGCCCAGAGAGGCCAGGGGTCCACGCTGGGCCTAGAGG ACTGGCCCACTCTCCCCATTTACCAGACGACTGGGGCCTCCACACTAAGGAGGGGCAGGGCTGGCAGTGACGAGGGAAACCTCTCGCTGA GGGTTGGGGCAAAGTCACCCCTGGAAATCGAAGGGGCCGCTGGTGGTCTCTTGAGGTCCACCAGCCTCAAATGCATCTCTTCAGACGGTG TTGGGGGCACAACCCTACTCCCCGAAAAGTCGAAAACCCAATTCAGTTCCTGCGAGTCCCTCTTAGAATCCAGACCGAGCATGGGGAGAA AACTGAGCTCTCCGACCACACCCAGGGACATGCTGTTGTCGCCCACACTGCGTCCTCGGAGGCGGTGTCTGGAGTCCTCTGTGGACGATG CGGGCTGTCCAGACCTTGGAAAGGAGCCGCTTGTTTTCCAGAACCGCCAGTTTGCCCACCTGATGGAGGAACCTCTAGGCAGTGACCCAT TCAGCTGGAAACTCCCAAGCCTCGACTACGAACGCAAGACCAAAGTGGACTTCGATGACTTCCTCCCAGCTATCCGGAAGCCCCAGACAC CTACCTCCTTGGCTGGATCAGCCAAAGGTGGGCAAGACGGTTCACAGCGTTCAAGCATCCACTTTGAAACGGAAGAGGCTAACCGTTCCT TTCTCTCGGGGATCAAGACCATTTTGAAGAAGAGCCCGGAGCCCAAGGAGGATCCCGCTCACCTGTCTGACTCGTCCTCATCCTCCGGCT CCATCGTGTCCTTCAAAAGTGCTGACAGCATCAAAAGTCGACCAGGAATCCCACGACTTGCGGGTGACGGTGGCGAGCGAACGTCCCCCG AGCGGAGAGAGCCAGGGACGGGGAGGAAAGACGACGATGTTGCGAGCATAATGAAGAAATACCTCCAGAAGTAGGAACCAGTTCAGGTAA >In-frame_ITGA2_ENST00000296585_chr5_52353931_+_MYO18B_ENST00000335473_chr22_26388329_+_3475nt TTTTCCCTGCTCTCACCGGGCGGGGGAGAGAAGCCCTCTGGACAGCTTCTAGAGTGTGCAGGTTCTCGTATCCCTCGGCCAAGGGTATCC TCTGCAAACCTCTGCAAACCCAGCGCAACTACGGTCCCCCGGTCAGACCCAGGATGGGGCCAGAACGGACAGGGGCCGCGCCGCTGCCGC TGCTGCTGGTGTTAGCGCTCAGTCAAGGCATTTTAAATTGTTGTTTGGCCTACAATGTTGGTCTCCCAGAAGCAAAAATATTTTCCGGTC CTTCAAGTGAACAGTTTGGCTATGCAGTGCAGCAGTTTATAAATCCAAAAGGCAACTGGTTACTGGTTGGTTCACCCTGGAGTGGCTTTC CTGAGAACCGAATGGGAGATGTGTATAAATGTCCTGTTGACCTATCCACTGCCACATGTGAAAAACTAAATTTGCAAACTTCAACAAGCA TTCCAAATGTTACTGAGATGAAAACCAACATGAGCCTCGGCTTGATCCTCACCAGGAACATGGGAACTGGAGGTTTTCTCACATGTGGTC CTCTGTGGGCACAGCAATGTGGGAATCAGTATTACACAACGGGTGTGTGTTCTGACATCAGTCCTGATTTTCAGCTCTCAGCCAGCTTCT CACCTGCAACTCAGCCCTGCCCTTCCCTCATAGATGTTGTGGTTGTGTGTGATGAATCAAATAGTATTTATCCTTGGGATGCAGTAAAGA ATTTTTTGGAAAAATTTGTACAAGGCCTGGATATAGGCCCCACAAAGACACAGGTGGGGTTAATTCAGTATGCCAATAATCCAAGAGTTG TGTTTAACTTGAACACATATAAAACCAAAGAAGAAATGATTGTAGCAACATCCCAGACATCCCAATATGGTGGGGACCTCACAAACACAT TCGGAGCAATTCAATATGCAAGAAAATATGCTTATTCAGCAGCTTCTGGTGGGCGACGAAGTGCTACGAAAGTAATGGTAGTTGTAACTG ACGGTGAATCACATGATGGTTCAATGTTGAAAGCTGTGATTGATCAATGCAACCATGACAATATACTGAGGTTTGGCATAGCAGTTCTTG GGTACTTAAACAGAAACGCCCTTGATACTAAAAATTTAATAAAAGAAATAAAAGCAATCGCTAGTATTCCAACAGAAAGATACTTTTTCA ATGTGTCTGATGAAGCAGCTCTACTAGAAAAGGCTGGGACATTAGGAGAACAAATTTTCAGCATTGAAGGTACTGTTCAAGGAGGAGACA ACTTTCAGATGGAAATGTCACAAGTGGGATTCAGTGCAGATTACTCTTCTCAAAATGAGAAGTACGTGGAGGAACTTGCAGCAGTGAGGC AAACCCTCCAGACAGACCTGGAGACATCCATTCGGCGGATTGCCGACCTGCAGGCTGCCTTGGAAGAAGTGGCATCCAGTGACAGTGATA CTGAGAGTGTCCAGACGGCAGTGGATTGTGGCAGCAGCGGCCGAAAAGAGATGGATAACGTCTCCATCCTCAGCTCCCAGCCAGAGGGCA GCCTGCAGTCCTGGTTGAGCTGTACTCTGTCCCTGGCCACAGATACTATGAGGACTCCTTCTCGACAGTCAGCCACCAGCAGCCGCATCC TCAGCCCCAGGATAAACGAAGAGGCTGGGGACACTGAGAGGACCCAGTCGGCATTGGCACTGAGCAGAGCCCGGTCCACCAATGTCCACA GCAAGACCTCAGGAGACAAGCCTGTTTCTCCCCACTTTGTCCGCCGGCAAAAGTACTGTCATTTTGGGGACGGCGAAGTGCTTGCCGTCC AGAGAAAGTCCACAGAGAGATTAGAACCTGCTTCCTCTCCCCTGGCTTCTCGGAGTACAAATACATCCCCGCTGTCGAGGGAAAAGCTGC CCAGTCCTTCAGCGGCCCTCTCGGAGTTCGTGGAAGGGCTCCGGAGGAAGAGAGCCCAGAGAGGCCAGGGGTCCACGCTGGGCCTAGAGG ACTGGCCCACTCTCCCCATTTACCAGACGACTGGGGCCTCCACACTAAGGAGGGGCAGGGCTGGCAGTGACGAGGGAAACCTCTCGCTGA GGGTTGGGGCAAAGTCACCCCTGGAAATCGAAGGGGCCGCTGGTGGTCTCTTGAGGTCCACCAGCCTCAAATGCATCTCTTCAGACGGTG TTGGGGGCACAACCCTACTCCCCGAAAAGTCGAAAACCCAATTCAGTTCCTGCGAGTCCCTCTTAGAATCCAGACCGAGCATGGGGAGAA AACTGAGCTCTCCGACCACACCCAGGGACATGCTGTTGTCGCCCACACTGCGTCCTCGGAGGCGGTGTCTGGAGTCCTCTGTGGACGATG CGGGCTGTCCAGACCTTGGAAAGGAGCCGCTTGTTTTCCAGAACCGCCAGTTTGCCCACCTGATGGAGGAACCTCTAGGCAGTGACCCAT TCAGCTGGAAACTCCCAAGCCTCGACTACGAACGCAAGACCAAAGTGGACTTCGATGACTTCCTCCCAGCTATCCGGAAGCCCCAGACAC CTACCTCCTTGGCTGGATCAGCCAAAGGTGGGCAAGACGGTTCACAGCGTTCAAGCATCCACTTTGAAACGGAAGAGGCTAACCGTTCCT TTCTCTCGGGGATCAAGACCATTTTGAAGAAGAGCCCGGAGCCCAAGGAGGATCCCGCTCACCTGTCTGACTCGTCCTCATCCTCCGGCT CCATCGTGTCCTTCAAAAGTGCTGACAGCATCAAAAGTCGACCAGGAATCCCACGACTTGCGGGTGACGGTGGCGAGCGAACGTCCCCCG AGCGGAGAGAGCCAGGGACGGGGAGGAAAGACGACGATGTTGCGAGCATAATGAAGAAATACCTCCAGAAGTAGGAACCAGTTCAGCCTC CTTGAAGCTGCCCTTGAAGACTTCCCGACTCTACAATAACTTGGAGACAGAGAGACTGGCCAGGCCTCCCCGGTGGCCAGAGCCAGCCAG CATGGCCACCCTCAAGAGGCGAGATGAGCCCACAGAGGCATATCCTGCGGGGATGCTGGGCTCCCAGTGTGGTTGGCCTGAACAAAATAA AGTGTTGACTCCTGGGCATCTGTGCCTTCTCTATGGCCTTGCTACCTGGGATTCCAGAGAGTTGATGGGGTGCAGATAGGGGTAGGACTG TTAGAATAGAACCAACCCAAACTGTGTGTAGTTTGGGGTGTATACTTCTATTTCTCTTCCTACATGTCTACATGCCATGACCTTCCTCCT CCTCTTCACTTGGCCAGTTTCAGCTCACTTCCTCCAGGAAGTCTTTCCTGATATATCAAACTGAAACAAATGCTCCTCCTCCATGCTCCC TTAATCCCCATGCTTGTCGATTATATTCCTTTGCCAATTCATTTCTCTATCCTGTGTATGTATAAGTGTGTACAAGCATTCAAGAAACTG >In-frame_ITGA2_ENST00000296585_chr5_52353931_+_MYO18B_ENST00000407587_chr22_26388329_+_3078nt TTTTCCCTGCTCTCACCGGGCGGGGGAGAGAAGCCCTCTGGACAGCTTCTAGAGTGTGCAGGTTCTCGTATCCCTCGGCCAAGGGTATCC TCTGCAAACCTCTGCAAACCCAGCGCAACTACGGTCCCCCGGTCAGACCCAGGATGGGGCCAGAACGGACAGGGGCCGCGCCGCTGCCGC TGCTGCTGGTGTTAGCGCTCAGTCAAGGCATTTTAAATTGTTGTTTGGCCTACAATGTTGGTCTCCCAGAAGCAAAAATATTTTCCGGTC CTTCAAGTGAACAGTTTGGCTATGCAGTGCAGCAGTTTATAAATCCAAAAGGCAACTGGTTACTGGTTGGTTCACCCTGGAGTGGCTTTC CTGAGAACCGAATGGGAGATGTGTATAAATGTCCTGTTGACCTATCCACTGCCACATGTGAAAAACTAAATTTGCAAACTTCAACAAGCA TTCCAAATGTTACTGAGATGAAAACCAACATGAGCCTCGGCTTGATCCTCACCAGGAACATGGGAACTGGAGGTTTTCTCACATGTGGTC CTCTGTGGGCACAGCAATGTGGGAATCAGTATTACACAACGGGTGTGTGTTCTGACATCAGTCCTGATTTTCAGCTCTCAGCCAGCTTCT CACCTGCAACTCAGCCCTGCCCTTCCCTCATAGATGTTGTGGTTGTGTGTGATGAATCAAATAGTATTTATCCTTGGGATGCAGTAAAGA ATTTTTTGGAAAAATTTGTACAAGGCCTGGATATAGGCCCCACAAAGACACAGGTGGGGTTAATTCAGTATGCCAATAATCCAAGAGTTG TGTTTAACTTGAACACATATAAAACCAAAGAAGAAATGATTGTAGCAACATCCCAGACATCCCAATATGGTGGGGACCTCACAAACACAT TCGGAGCAATTCAATATGCAAGAAAATATGCTTATTCAGCAGCTTCTGGTGGGCGACGAAGTGCTACGAAAGTAATGGTAGTTGTAACTG ACGGTGAATCACATGATGGTTCAATGTTGAAAGCTGTGATTGATCAATGCAACCATGACAATATACTGAGGTTTGGCATAGCAGTTCTTG GGTACTTAAACAGAAACGCCCTTGATACTAAAAATTTAATAAAAGAAATAAAAGCAATCGCTAGTATTCCAACAGAAAGATACTTTTTCA ATGTGTCTGATGAAGCAGCTCTACTAGAAAAGGCTGGGACATTAGGAGAACAAATTTTCAGCATTGAAGGTACTGTTCAAGGAGGAGACA ACTTTCAGATGGAAATGTCACAAGTGGGATTCAGTGCAGATTACTCTTCTCAAAATGAGAAGTACGTGGAGGAACTTGCAGCAGTGAGGC AAACCCTCCAGACAGACCTGGAGACATCCATTCGGCGGATTGCCGACCTGCAGGCTGCCTTGGAAGAAGTGGCATCCAGTGACAGTGATA CTGAGAGTGTCCAGACGGCAGTGGATTGTGGCAGCAGCGGCCGAAAAGAGATGGATAACGTCTCCATCCTCAGCTCCCAGCCAGAGGGCA GCCTGCAGTCCTGGTTGAGCTGTACTCTGTCCCTGGCCACAGATACTATGAGGACTCCTTCTCGACAGTCAGCCACCAGCAGCCGCATCC TCAGCCCCAGGATAAACGAAGAGGCTGGGGACACTGAGAGGACCCAGTCGGCATTGGCACTGAGCAGAGCCCGGTCCACCAATGTCCACA GCAAGACCTCAGGAGACAAGCCTGTTTCTCCCCACTTTGTCCGCCGGCAAAAGTACTGTCATTTTGGGGACGGCGAAGTGCTTGCCGTCC AGAGAAAGTCCACAGAGAGATTAGAACCTGCTTCCTCTCCCCTGGCTTCTCGGAGTACAAATACATCCCCGCTGTCGAGGGAAAAGCTGC CCAGTCCTTCAGCGGCCCTCTCGGAGTTCGTGGAAGGGCTCCGGAGGAAGAGAGCCCAGAGAGGCCAGGGGTCCACGCTGGGCCTAGAGG ACTGGCCCACTCTCCCCATTTACCAGACGACTGGGGCCTCCACACTAAGGAGGGGCAGGGCTGGCAGTGACGAGGGAAACCTCTCGCTGA GGGTTGGGGCAAAGTCACCCCTGGAAATCGAAGGGGCCGCTGGTGGTCTCTTGAGGTCCACCAGCCTCAAATGCATCTCTTCAGACGGTG TTGGGGGCACAACCCTACTCCCCGAAAAGTCGAAAACCCAATTCAGTTCCTGCGAGTCCCTCTTAGAATCCAGACCGAGCATGGGGAGAA AACTGAGCTCTCCGACCACACCCAGGGACATGCTGTTGTCGCCCACACTGCGTCCTCGGAGGCGGTGTCTGGAGTCCTCTGTGGACGATG CGGGCTGTCCAGACCTTGGAAAGGAGCCGCTTGTTTTCCAGAACCGCCAGTTTGCCCACCTGATGGAGGAACCTCTAGGCAGTGACCCAT TCAGCTGGAAACTCCCAAGCCTCGACTACGAACGCAAGACCAAAGTGGACTTCGATGACTTCCTCCCAGCTATCCGGAAGCCCCAGACAC CTACCTCCTTGGCTGGATCAGCCAAAGGTGGGCAAGACGGTTCACAGCGTTCAAGCATCCACTTTGAAACGGAAGAGGCTAACCGTTCCT TTCTCTCGGGGATCAAGACCATTTTGAAGAAGAGCCCGGAGCCCAAGGAGGATCCCGCTCACCTGTCTGACTCGTCCTCATCCTCCGGCT CCATCGTGTCCTTCAAAAGTGCTGACAGCATCAAAAGTCGACCAGGAATCCCACGACTTGCGGGTGACGGTGGCGAGCGAACGTCCCCCG AGCGGAGAGAGCCAGGGACGGGGAGGAAAGACGACGATGTTGCGAGCATAATGAAGAAATACCTCCAGAAGTAGGAACCAGTTCAGCCTC CTTGAAGCTGCCCTTGAAGACTTCCCGACTCTACAATAACTTGGAGACAGAGAGACTGGCCAGGCCTCCCCGGTGGCCAGAGCCAGCCAG CATGGCCACCCTCAAGAGGCGAGATGAGCCCACAGAGGCATATCCTGCGGGGATGCTGGGCTCCCAGTGTGGTTGGCCTGAACAAAATAA 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FusionGenePPI for ITGA2_MYO18B |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| ITGA2 | COL1A1, CD46, AUP1, MMP1, LAMA1, RABIF, PSMD4, SHARPIN, ITGB1, ERGIC1, PDIA3, ALB, ATF2, LGALS3, LGALS8, BTNL8, ZACN, RSRP1, TSC22D2, MGAT4C, TMED6, SCGB1D1, SERPINA12 | MYO18B | PSMC5, SRPK2 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| Hgene | ITGA2 | chr5:52353931 | chr22:26388329 | ENST00000296585 | + | 10 | 30 | 1155_1161 | 391 | 1182 | HPS5 |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for ITGA2_MYO18B |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for ITGA2_MYO18B |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | ITGA2 | C0014175 | Endometriosis | 1 | CTD_human |
| Hgene | ITGA2 | C0017639 | Gliosis | 1 | CTD_human |
| Hgene | ITGA2 | C0020429 | Hyperalgesia | 1 | CTD_human |
| Hgene | ITGA2 | C0035328 | Retinal Vein Occlusion | 1 | CTD_human |
| Tgene | MYO18B | C0025500 | Mesothelioma | 1 | CTD_human |
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