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Fusion gene ID: 17634 |
FusionGeneSummary for IPO7_AKIP1 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: IPO7_AKIP1 | Fusion gene ID: 17634 | Hgene | Tgene | Gene symbol | IPO7 | AKIP1 | Gene ID | 10527 | 56672 |
| Gene name | importin 7 | A-kinase interacting protein 1 | |
| Synonyms | Imp7|RANBP7 | BCA3|C11orf17 | |
| Cytomap | 11p15.4 | 11p15.4 | |
| Type of gene | protein-coding | protein-coding | |
| Description | importin-7RAN-binding protein 7 | A-kinase-interacting protein 1A kinase (PRKA) interacting protein 1breast cancer associated gene 3koyt binding protein 1koyt binding protein 2koyt binding protein 3proline-rich protein BCA3 | |
| Modification date | 20180523 | 20180519 | |
| UniProtAcc | O95373 | Q9NQ31 | |
| Ensembl transtripts involved in fusion gene | ENST00000379719, ENST00000533680, | ENST00000299576, ENST00000309377, ENST00000309357, ENST00000529876, ENST00000525005, ENST00000534506, ENST00000396648, ENST00000534147, | |
| Fusion gene scores | * DoF score | 8 X 5 X 5=200 | 4 X 4 X 2=32 |
| # samples | 9 | 5 | |
| ** MAII score | log2(9/200*10)=-1.15200309344505 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(5/32*10)=0.643856189774725 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
| Context | PubMed: IPO7 [Title/Abstract] AND AKIP1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | Oncogene involved fusion gene, in-frame and retained their domain. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | LUAD | TCGA-55-6969-01A | IPO7 | chr11 | 9442245 | + | AKIP1 | chr11 | 8936373 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000379719 | ENST00000299576 | IPO7 | chr11 | 9442245 | + | AKIP1 | chr11 | 8936373 | + |
| In-frame | ENST00000379719 | ENST00000309377 | IPO7 | chr11 | 9442245 | + | AKIP1 | chr11 | 8936373 | + |
| In-frame | ENST00000379719 | ENST00000309357 | IPO7 | chr11 | 9442245 | + | AKIP1 | chr11 | 8936373 | + |
| In-frame | ENST00000379719 | ENST00000529876 | IPO7 | chr11 | 9442245 | + | AKIP1 | chr11 | 8936373 | + |
| In-frame | ENST00000379719 | ENST00000525005 | IPO7 | chr11 | 9442245 | + | AKIP1 | chr11 | 8936373 | + |
| In-frame | ENST00000379719 | ENST00000534506 | IPO7 | chr11 | 9442245 | + | AKIP1 | chr11 | 8936373 | + |
| In-frame | ENST00000379719 | ENST00000396648 | IPO7 | chr11 | 9442245 | + | AKIP1 | chr11 | 8936373 | + |
| In-frame | ENST00000379719 | ENST00000534147 | IPO7 | chr11 | 9442245 | + | AKIP1 | chr11 | 8936373 | + |
| intron-3CDS | ENST00000533680 | ENST00000299576 | IPO7 | chr11 | 9442245 | + | AKIP1 | chr11 | 8936373 | + |
| intron-3CDS | ENST00000533680 | ENST00000309377 | IPO7 | chr11 | 9442245 | + | AKIP1 | chr11 | 8936373 | + |
| intron-3CDS | ENST00000533680 | ENST00000309357 | IPO7 | chr11 | 9442245 | + | AKIP1 | chr11 | 8936373 | + |
| intron-3CDS | ENST00000533680 | ENST00000529876 | IPO7 | chr11 | 9442245 | + | AKIP1 | chr11 | 8936373 | + |
| intron-3CDS | ENST00000533680 | ENST00000525005 | IPO7 | chr11 | 9442245 | + | AKIP1 | chr11 | 8936373 | + |
| intron-3CDS | ENST00000533680 | ENST00000534506 | IPO7 | chr11 | 9442245 | + | AKIP1 | chr11 | 8936373 | + |
| intron-3CDS | ENST00000533680 | ENST00000396648 | IPO7 | chr11 | 9442245 | + | AKIP1 | chr11 | 8936373 | + |
| intron-3CDS | ENST00000533680 | ENST00000534147 | IPO7 | chr11 | 9442245 | + | AKIP1 | chr11 | 8936373 | + |
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FusionProtFeatures for IPO7_AKIP1 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| IPO7 | AKIP1 |
| Functions in nuclear protein import, either by acting asautonomous nuclear transport receptor or as an adapter-likeprotein in association with the importin-beta subunit KPNB1.Acting autonomously, is thought to serve itself as receptor fornuclear localization signals (NLS) and to promote translocation ofimport substrates through the nuclear pore complex (NPC) by anenergy requiring, Ran-dependent mechanism. At the nucleoplasmicside of the NPC, Ran binds to importin, the importin/substratecomplex dissociates and importin is re-exported from the nucleusto the cytoplasm where GTP hydrolysis releases Ran. Thedirectionality of nuclear import is thought to be conferred by anasymmetric distribution of the GTP- and GDP-bound forms of Ranbetween the cytoplasm and nucleus. Mediates autonomously thenuclear import of ribosomal proteins RPL23A, RPS7 and RPL5. Bindsto a beta-like import receptor binding (BIB) domain of RPL23A. Inassociation with KPNB1 mediates the nuclear import of H1 histoneand the Ran-binding site of IPO7 is not required but synergizeswith that of KPNB1 in importin/substrate complex dissociation. Invitro, mediates nuclear import of H2A, H2B, H3 and H4 histones.{ECO:0000269|PubMed:10228156, ECO:0000269|PubMed:9687515}. (Microbial infection) Mediates the nuclear import ofHIV-1 reverse transcription complex (RTC) integrase. Binds andmediates the nuclear import of HIV-1 Rev.{ECO:0000269|PubMed:12853482, ECO:0000269|PubMed:16704975}. | Enhances NF-kappa-B transcriptional activity byregulating the nuclear localization of the NF-kappa-B subunit RELAand promoting the phosphorylation of RELA by PRKACA. Regulates theeffect of the cAMP-dependent protein kinase signaling pathway onthe NF-kappa-B activation cascade. {ECO:0000269|PubMed:18178962,ECO:0000269|PubMed:20562110}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | IPO7 | chr11:9442245 | chr11:8936373 | ENST00000379719 | + | 8 | 25 | 22_101 | 302 | 1039 | Domain | Importin N-terminal |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >IPO7 | chr11:9442245 | chr11:8936373 | ENST00000379719 | + | 8 | 25 | 885_957 | 302 | 1039 | Compositional bias | Note=Asp-rich |
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FusionGeneSequence for IPO7_AKIP1 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_IPO7_ENST00000379719_chr11_9442245_+_AKIP1_ENST00000299576_chr11_8936373_+_412aa MDPNTIIEALRGTMDPALREAAERQLNEAHKSLNFVSTLLQITMSEQLDLPVRQAGVIYLKNMITQYWPDRETAPGDISPYTIPEEDRHC IRENIVEAIIHSPELIRVQLTTCIHHIIKHDYPSRWTAIVDKIGFYLQSDNSACWLGILLCLYQLVKNYEYKKPEERSPLVAAMQHFLPV LKDRFIQLLSDQSDQSVLIQKQIFKIFYALVQYTLPLELINQQNLTEWIEILKTVVNRDVPNETLQVEEDDRPELPWWKCKKWALHILAR LFERYGSPGNVSKEYNEFAEVFLKAFAVGVQQKYYSSVPEEGGATHVYRYHRGESKLHMCLDIGNGQRKDRKKTSLGPGGSYQISEHAPE >In-frame_IPO7_ENST00000379719_chr11_9442245_+_AKIP1_ENST00000309377_chr11_8936373_+_412aa MDPNTIIEALRGTMDPALREAAERQLNEAHKSLNFVSTLLQITMSEQLDLPVRQAGVIYLKNMITQYWPDRETAPGDISPYTIPEEDRHC IRENIVEAIIHSPELIRVQLTTCIHHIIKHDYPSRWTAIVDKIGFYLQSDNSACWLGILLCLYQLVKNYEYKKPEERSPLVAAMQHFLPV LKDRFIQLLSDQSDQSVLIQKQIFKIFYALVQYTLPLELINQQNLTEWIEILKTVVNRDVPNETLQVEEDDRPELPWWKCKKWALHILAR LFERYGSPGNVSKEYNEFAEVFLKAFAVGVQQKYYSSVPEEGGATHVYRYHRGESKLHMCLDIGNGQRKDRKKTSLGPGGSYQISEHAPE >In-frame_IPO7_ENST00000379719_chr11_9442245_+_AKIP1_ENST00000309357_chr11_8936373_+_385aa MDPNTIIEALRGTMDPALREAAERQLNEAHKSLNFVSTLLQITMSEQLDLPVRQAGVIYLKNMITQYWPDRETAPGDISPYTIPEEDRHC IRENIVEAIIHSPELIRVQLTTCIHHIIKHDYPSRWTAIVDKIGFYLQSDNSACWLGILLCLYQLVKNYEYKKPEERSPLVAAMQHFLPV LKDRFIQLLSDQSDQSVLIQKQIFKIFYALVQYTLPLELINQQNLTEWIEILKTVVNRDVPNETLQVEEDDRPELPWWKCKKWALHILAR LFERYGSPGNVSKEYNEFAEVFLKAFAVGVQQKYYSSVPEEGGATHVYRYHRGESKLHMCLDIGNGQAENISKDLYIEVYPGTYSVTVGS >In-frame_IPO7_ENST00000379719_chr11_9442245_+_AKIP1_ENST00000529876_chr11_8936373_+_397aa MDPNTIIEALRGTMDPALREAAERQLNEAHKSLNFVSTLLQITMSEQLDLPVRQAGVIYLKNMITQYWPDRETAPGDISPYTIPEEDRHC IRENIVEAIIHSPELIRVQLTTCIHHIIKHDYPSRWTAIVDKIGFYLQSDNSACWLGILLCLYQLVKNYEYKKPEERSPLVAAMQHFLPV LKDRFIQLLSDQSDQSVLIQKQIFKIFYALVQYTLPLELINQQNLTEWIEILKTVVNRDVPNETLQVEEDDRPELPWWKCKKWALHILAR LFERYGSPGNVSKEYNEFAEVFLKAFAVGVQQKYYSSVPEEGGATHVYRYHRGESKLHMCLDIGNGQRKDRKKTSLGPGGSYQISEHAPE >In-frame_IPO7_ENST00000379719_chr11_9442245_+_AKIP1_ENST00000525005_chr11_8936373_+_397aa MDPNTIIEALRGTMDPALREAAERQLNEAHKSLNFVSTLLQITMSEQLDLPVRQAGVIYLKNMITQYWPDRETAPGDISPYTIPEEDRHC IRENIVEAIIHSPELIRVQLTTCIHHIIKHDYPSRWTAIVDKIGFYLQSDNSACWLGILLCLYQLVKNYEYKKPEERSPLVAAMQHFLPV LKDRFIQLLSDQSDQSVLIQKQIFKIFYALVQYTLPLELINQQNLTEWIEILKTVVNRDVPNETLQVEEDDRPELPWWKCKKWALHILAR LFERYGSPGNVSKEYNEFAEVFLKAFAVGVQQKYYSSVPEEGGATHVYRYHRGESKLHMCLDIGNGQRKDRKKTSLGPGGSYQISEHAPE >In-frame_IPO7_ENST00000379719_chr11_9442245_+_AKIP1_ENST00000534506_chr11_8936373_+_397aa MDPNTIIEALRGTMDPALREAAERQLNEAHKSLNFVSTLLQITMSEQLDLPVRQAGVIYLKNMITQYWPDRETAPGDISPYTIPEEDRHC IRENIVEAIIHSPELIRVQLTTCIHHIIKHDYPSRWTAIVDKIGFYLQSDNSACWLGILLCLYQLVKNYEYKKPEERSPLVAAMQHFLPV LKDRFIQLLSDQSDQSVLIQKQIFKIFYALVQYTLPLELINQQNLTEWIEILKTVVNRDVPNETLQVEEDDRPELPWWKCKKWALHILAR LFERYGSPGNVSKEYNEFAEVFLKAFAVGVQQKYYSSVPEEGGATHVYRYHRGESKLHMCLDIGNGQRKDRKKTSLGPGGSYQISEHAPE >In-frame_IPO7_ENST00000379719_chr11_9442245_+_AKIP1_ENST00000396648_chr11_8936373_+_412aa MDPNTIIEALRGTMDPALREAAERQLNEAHKSLNFVSTLLQITMSEQLDLPVRQAGVIYLKNMITQYWPDRETAPGDISPYTIPEEDRHC IRENIVEAIIHSPELIRVQLTTCIHHIIKHDYPSRWTAIVDKIGFYLQSDNSACWLGILLCLYQLVKNYEYKKPEERSPLVAAMQHFLPV LKDRFIQLLSDQSDQSVLIQKQIFKIFYALVQYTLPLELINQQNLTEWIEILKTVVNRDVPNETLQVEEDDRPELPWWKCKKWALHILAR LFERYGSPGNVSKEYNEFAEVFLKAFAVGVQQKYYSSVPEEGGATHVYRYHRGESKLHMCLDIGNGQRKDRKKTSLGPGGSYQISEHAPE >In-frame_IPO7_ENST00000379719_chr11_9442245_+_AKIP1_ENST00000534147_chr11_8936373_+_412aa MDPNTIIEALRGTMDPALREAAERQLNEAHKSLNFVSTLLQITMSEQLDLPVRQAGVIYLKNMITQYWPDRETAPGDISPYTIPEEDRHC IRENIVEAIIHSPELIRVQLTTCIHHIIKHDYPSRWTAIVDKIGFYLQSDNSACWLGILLCLYQLVKNYEYKKPEERSPLVAAMQHFLPV LKDRFIQLLSDQSDQSVLIQKQIFKIFYALVQYTLPLELINQQNLTEWIEILKTVVNRDVPNETLQVEEDDRPELPWWKCKKWALHILAR LFERYGSPGNVSKEYNEFAEVFLKAFAVGVQQKYYSSVPEEGGATHVYRYHRGESKLHMCLDIGNGQRKDRKKTSLGPGGSYQISEHAPE |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_IPO7_ENST00000379719_chr11_9442245_+_AKIP1_ENST00000299576_chr11_8936373_+_1236nt ATGGACCCCAACACCATTATCGAGGCCCTGCGGGGCACTATGGACCCAGCCCTGCGTGAGGCCGCGGAGCGCCAGCTCAATGAAGCACAC AAGTCTCTGAATTTTGTCTCAACACTGCTCCAGATTACTATGTCGGAACAGCTGGATTTACCTGTGAGACAGGCAGGTGTTATCTATCTG AAAAATATGATAACACAGTATTGGCCTGATCGAGAAACAGCACCAGGGGATATATCCCCTTATACTATTCCAGAAGAAGATCGCCATTGT ATTCGAGAAAATATTGTAGAAGCCATTATCCATTCTCCTGAGCTCATCAGGGTACAGCTTACTACATGCATTCATCACATCATCAAACAT GATTATCCAAGCCGCTGGACTGCCATTGTGGACAAAATTGGCTTTTATCTTCAGTCCGATAACAGTGCTTGTTGGCTAGGAATTCTTCTT TGCCTTTATCAGCTTGTGAAAAATTATGAGTATAAAAAACCAGAGGAGCGGAGTCCATTGGTAGCAGCAATGCAGCATTTTCTGCCAGTT CTAAAGGATCGTTTTATCCAGCTTCTTTCTGACCAGTCTGATCAGTCTGTCCTCATCCAGAAACAGATATTCAAGATCTTCTATGCTCTT GTTCAGTATACACTACCACTGGAACTGATAAACCAACAGAACCTGACAGAATGGATAGAAATTTTAAAGACTGTTGTGAACAGGGATGTA CCTAATGAAACACTTCAAGTTGAAGAAGATGATCGACCTGAGTTACCATGGTGGAAATGCAAGAAGTGGGCCTTACATATTTTAGCAAGA CTTTTTGAAAGATATGGAAGCCCTGGCAATGTTTCCAAGGAGTATAATGAATTTGCTGAAGTATTTCTGAAGGCATTTGCTGTTGGTGTC CAGCAAAAATATTATTCATCTGTGCCAGAGGAAGGAGGGGCAACCCATGTCTATCGTTATCACAGAGGCGAGTCGAAGCTGCACATGTGC TTGGACATAGGGAATGGTCAGAGAAAAGACAGAAAAAAGACATCCCTTGGTCCTGGAGGCAGCTATCAAATATCAGAGCATGCTCCAGAG GCATCCCAGCCTGCTGAGAACATCTCTAAGGACCTCTACATAGAAGTATATCCAGGGACCTATTCTGTCACTGTGGGCTCAAATGACTTA >In-frame_IPO7_ENST00000379719_chr11_9442245_+_AKIP1_ENST00000309377_chr11_8936373_+_1236nt ATGGACCCCAACACCATTATCGAGGCCCTGCGGGGCACTATGGACCCAGCCCTGCGTGAGGCCGCGGAGCGCCAGCTCAATGAAGCACAC AAGTCTCTGAATTTTGTCTCAACACTGCTCCAGATTACTATGTCGGAACAGCTGGATTTACCTGTGAGACAGGCAGGTGTTATCTATCTG AAAAATATGATAACACAGTATTGGCCTGATCGAGAAACAGCACCAGGGGATATATCCCCTTATACTATTCCAGAAGAAGATCGCCATTGT ATTCGAGAAAATATTGTAGAAGCCATTATCCATTCTCCTGAGCTCATCAGGGTACAGCTTACTACATGCATTCATCACATCATCAAACAT GATTATCCAAGCCGCTGGACTGCCATTGTGGACAAAATTGGCTTTTATCTTCAGTCCGATAACAGTGCTTGTTGGCTAGGAATTCTTCTT TGCCTTTATCAGCTTGTGAAAAATTATGAGTATAAAAAACCAGAGGAGCGGAGTCCATTGGTAGCAGCAATGCAGCATTTTCTGCCAGTT CTAAAGGATCGTTTTATCCAGCTTCTTTCTGACCAGTCTGATCAGTCTGTCCTCATCCAGAAACAGATATTCAAGATCTTCTATGCTCTT GTTCAGTATACACTACCACTGGAACTGATAAACCAACAGAACCTGACAGAATGGATAGAAATTTTAAAGACTGTTGTGAACAGGGATGTA CCTAATGAAACACTTCAAGTTGAAGAAGATGATCGACCTGAGTTACCATGGTGGAAATGCAAGAAGTGGGCCTTACATATTTTAGCAAGA CTTTTTGAAAGATATGGAAGCCCTGGCAATGTTTCCAAGGAGTATAATGAATTTGCTGAAGTATTTCTGAAGGCATTTGCTGTTGGTGTC CAGCAAAAATATTATTCATCTGTGCCAGAGGAAGGAGGGGCAACCCATGTCTATCGTTATCACAGAGGCGAGTCGAAGCTGCACATGTGC TTGGACATAGGGAATGGTCAGAGAAAAGACAGAAAAAAGACATCCCTTGGTCCTGGAGGCAGCTATCAAATATCAGAGCATGCTCCAGAG GCATCCCAGCCTGCTGAGAACATCTCTAAGGACCTCTACATAGAAGTATATCCAGGGACCTATTCTGTCACTGTGGGCTCAAATGACTTA >In-frame_IPO7_ENST00000379719_chr11_9442245_+_AKIP1_ENST00000309357_chr11_8936373_+_1155nt ATGGACCCCAACACCATTATCGAGGCCCTGCGGGGCACTATGGACCCAGCCCTGCGTGAGGCCGCGGAGCGCCAGCTCAATGAAGCACAC AAGTCTCTGAATTTTGTCTCAACACTGCTCCAGATTACTATGTCGGAACAGCTGGATTTACCTGTGAGACAGGCAGGTGTTATCTATCTG AAAAATATGATAACACAGTATTGGCCTGATCGAGAAACAGCACCAGGGGATATATCCCCTTATACTATTCCAGAAGAAGATCGCCATTGT ATTCGAGAAAATATTGTAGAAGCCATTATCCATTCTCCTGAGCTCATCAGGGTACAGCTTACTACATGCATTCATCACATCATCAAACAT GATTATCCAAGCCGCTGGACTGCCATTGTGGACAAAATTGGCTTTTATCTTCAGTCCGATAACAGTGCTTGTTGGCTAGGAATTCTTCTT TGCCTTTATCAGCTTGTGAAAAATTATGAGTATAAAAAACCAGAGGAGCGGAGTCCATTGGTAGCAGCAATGCAGCATTTTCTGCCAGTT CTAAAGGATCGTTTTATCCAGCTTCTTTCTGACCAGTCTGATCAGTCTGTCCTCATCCAGAAACAGATATTCAAGATCTTCTATGCTCTT GTTCAGTATACACTACCACTGGAACTGATAAACCAACAGAACCTGACAGAATGGATAGAAATTTTAAAGACTGTTGTGAACAGGGATGTA CCTAATGAAACACTTCAAGTTGAAGAAGATGATCGACCTGAGTTACCATGGTGGAAATGCAAGAAGTGGGCCTTACATATTTTAGCAAGA CTTTTTGAAAGATATGGAAGCCCTGGCAATGTTTCCAAGGAGTATAATGAATTTGCTGAAGTATTTCTGAAGGCATTTGCTGTTGGTGTC CAGCAAAAATATTATTCATCTGTGCCAGAGGAAGGAGGGGCAACCCATGTCTATCGTTATCACAGAGGCGAGTCGAAGCTGCACATGTGC TTGGACATAGGGAATGGTCAGGCTGAGAACATCTCTAAGGACCTCTACATAGAAGTATATCCAGGGACCTATTCTGTCACTGTGGGCTCA >In-frame_IPO7_ENST00000379719_chr11_9442245_+_AKIP1_ENST00000529876_chr11_8936373_+_1191nt ATGGACCCCAACACCATTATCGAGGCCCTGCGGGGCACTATGGACCCAGCCCTGCGTGAGGCCGCGGAGCGCCAGCTCAATGAAGCACAC AAGTCTCTGAATTTTGTCTCAACACTGCTCCAGATTACTATGTCGGAACAGCTGGATTTACCTGTGAGACAGGCAGGTGTTATCTATCTG AAAAATATGATAACACAGTATTGGCCTGATCGAGAAACAGCACCAGGGGATATATCCCCTTATACTATTCCAGAAGAAGATCGCCATTGT ATTCGAGAAAATATTGTAGAAGCCATTATCCATTCTCCTGAGCTCATCAGGGTACAGCTTACTACATGCATTCATCACATCATCAAACAT GATTATCCAAGCCGCTGGACTGCCATTGTGGACAAAATTGGCTTTTATCTTCAGTCCGATAACAGTGCTTGTTGGCTAGGAATTCTTCTT TGCCTTTATCAGCTTGTGAAAAATTATGAGTATAAAAAACCAGAGGAGCGGAGTCCATTGGTAGCAGCAATGCAGCATTTTCTGCCAGTT CTAAAGGATCGTTTTATCCAGCTTCTTTCTGACCAGTCTGATCAGTCTGTCCTCATCCAGAAACAGATATTCAAGATCTTCTATGCTCTT GTTCAGTATACACTACCACTGGAACTGATAAACCAACAGAACCTGACAGAATGGATAGAAATTTTAAAGACTGTTGTGAACAGGGATGTA CCTAATGAAACACTTCAAGTTGAAGAAGATGATCGACCTGAGTTACCATGGTGGAAATGCAAGAAGTGGGCCTTACATATTTTAGCAAGA CTTTTTGAAAGATATGGAAGCCCTGGCAATGTTTCCAAGGAGTATAATGAATTTGCTGAAGTATTTCTGAAGGCATTTGCTGTTGGTGTC CAGCAAAAATATTATTCATCTGTGCCAGAGGAAGGAGGGGCAACCCATGTCTATCGTTATCACAGAGGCGAGTCGAAGCTGCACATGTGC TTGGACATAGGGAATGGTCAGAGAAAAGACAGAAAAAAGACATCCCTTGGTCCTGGAGGCAGCTATCAAATATCAGAGCATGCTCCAGAG GCATCCCAGCCTGTGAGTACGGAACTGCTTACGCACTGGGTTTCACCACCGTTGCAACTCCATGAACCAGTTGACATGGTTCTTAGAGGG >In-frame_IPO7_ENST00000379719_chr11_9442245_+_AKIP1_ENST00000525005_chr11_8936373_+_1191nt ATGGACCCCAACACCATTATCGAGGCCCTGCGGGGCACTATGGACCCAGCCCTGCGTGAGGCCGCGGAGCGCCAGCTCAATGAAGCACAC AAGTCTCTGAATTTTGTCTCAACACTGCTCCAGATTACTATGTCGGAACAGCTGGATTTACCTGTGAGACAGGCAGGTGTTATCTATCTG AAAAATATGATAACACAGTATTGGCCTGATCGAGAAACAGCACCAGGGGATATATCCCCTTATACTATTCCAGAAGAAGATCGCCATTGT ATTCGAGAAAATATTGTAGAAGCCATTATCCATTCTCCTGAGCTCATCAGGGTACAGCTTACTACATGCATTCATCACATCATCAAACAT GATTATCCAAGCCGCTGGACTGCCATTGTGGACAAAATTGGCTTTTATCTTCAGTCCGATAACAGTGCTTGTTGGCTAGGAATTCTTCTT TGCCTTTATCAGCTTGTGAAAAATTATGAGTATAAAAAACCAGAGGAGCGGAGTCCATTGGTAGCAGCAATGCAGCATTTTCTGCCAGTT CTAAAGGATCGTTTTATCCAGCTTCTTTCTGACCAGTCTGATCAGTCTGTCCTCATCCAGAAACAGATATTCAAGATCTTCTATGCTCTT GTTCAGTATACACTACCACTGGAACTGATAAACCAACAGAACCTGACAGAATGGATAGAAATTTTAAAGACTGTTGTGAACAGGGATGTA CCTAATGAAACACTTCAAGTTGAAGAAGATGATCGACCTGAGTTACCATGGTGGAAATGCAAGAAGTGGGCCTTACATATTTTAGCAAGA CTTTTTGAAAGATATGGAAGCCCTGGCAATGTTTCCAAGGAGTATAATGAATTTGCTGAAGTATTTCTGAAGGCATTTGCTGTTGGTGTC CAGCAAAAATATTATTCATCTGTGCCAGAGGAAGGAGGGGCAACCCATGTCTATCGTTATCACAGAGGCGAGTCGAAGCTGCACATGTGC TTGGACATAGGGAATGGTCAGAGAAAAGACAGAAAAAAGACATCCCTTGGTCCTGGAGGCAGCTATCAAATATCAGAGCATGCTCCAGAG GCATCCCAGCCTGTGAGTACGGAACTGCTTACGCACTGGGTTTCACCACCGTTGCAACTCCATGAACCAGTTGACATGGTTCTTAGAGGG >In-frame_IPO7_ENST00000379719_chr11_9442245_+_AKIP1_ENST00000534506_chr11_8936373_+_1191nt ATGGACCCCAACACCATTATCGAGGCCCTGCGGGGCACTATGGACCCAGCCCTGCGTGAGGCCGCGGAGCGCCAGCTCAATGAAGCACAC AAGTCTCTGAATTTTGTCTCAACACTGCTCCAGATTACTATGTCGGAACAGCTGGATTTACCTGTGAGACAGGCAGGTGTTATCTATCTG AAAAATATGATAACACAGTATTGGCCTGATCGAGAAACAGCACCAGGGGATATATCCCCTTATACTATTCCAGAAGAAGATCGCCATTGT ATTCGAGAAAATATTGTAGAAGCCATTATCCATTCTCCTGAGCTCATCAGGGTACAGCTTACTACATGCATTCATCACATCATCAAACAT GATTATCCAAGCCGCTGGACTGCCATTGTGGACAAAATTGGCTTTTATCTTCAGTCCGATAACAGTGCTTGTTGGCTAGGAATTCTTCTT TGCCTTTATCAGCTTGTGAAAAATTATGAGTATAAAAAACCAGAGGAGCGGAGTCCATTGGTAGCAGCAATGCAGCATTTTCTGCCAGTT CTAAAGGATCGTTTTATCCAGCTTCTTTCTGACCAGTCTGATCAGTCTGTCCTCATCCAGAAACAGATATTCAAGATCTTCTATGCTCTT GTTCAGTATACACTACCACTGGAACTGATAAACCAACAGAACCTGACAGAATGGATAGAAATTTTAAAGACTGTTGTGAACAGGGATGTA CCTAATGAAACACTTCAAGTTGAAGAAGATGATCGACCTGAGTTACCATGGTGGAAATGCAAGAAGTGGGCCTTACATATTTTAGCAAGA CTTTTTGAAAGATATGGAAGCCCTGGCAATGTTTCCAAGGAGTATAATGAATTTGCTGAAGTATTTCTGAAGGCATTTGCTGTTGGTGTC CAGCAAAAATATTATTCATCTGTGCCAGAGGAAGGAGGGGCAACCCATGTCTATCGTTATCACAGAGGCGAGTCGAAGCTGCACATGTGC TTGGACATAGGGAATGGTCAGAGAAAAGACAGAAAAAAGACATCCCTTGGTCCTGGAGGCAGCTATCAAATATCAGAGCATGCTCCAGAG GCATCCCAGCCTGTGAGTACGGAACTGCTTACGCACTGGGTTTCACCACCGTTGCAACTCCATGAACCAGTTGACATGGTTCTTAGAGGG >In-frame_IPO7_ENST00000379719_chr11_9442245_+_AKIP1_ENST00000396648_chr11_8936373_+_1236nt ATGGACCCCAACACCATTATCGAGGCCCTGCGGGGCACTATGGACCCAGCCCTGCGTGAGGCCGCGGAGCGCCAGCTCAATGAAGCACAC AAGTCTCTGAATTTTGTCTCAACACTGCTCCAGATTACTATGTCGGAACAGCTGGATTTACCTGTGAGACAGGCAGGTGTTATCTATCTG AAAAATATGATAACACAGTATTGGCCTGATCGAGAAACAGCACCAGGGGATATATCCCCTTATACTATTCCAGAAGAAGATCGCCATTGT ATTCGAGAAAATATTGTAGAAGCCATTATCCATTCTCCTGAGCTCATCAGGGTACAGCTTACTACATGCATTCATCACATCATCAAACAT GATTATCCAAGCCGCTGGACTGCCATTGTGGACAAAATTGGCTTTTATCTTCAGTCCGATAACAGTGCTTGTTGGCTAGGAATTCTTCTT TGCCTTTATCAGCTTGTGAAAAATTATGAGTATAAAAAACCAGAGGAGCGGAGTCCATTGGTAGCAGCAATGCAGCATTTTCTGCCAGTT CTAAAGGATCGTTTTATCCAGCTTCTTTCTGACCAGTCTGATCAGTCTGTCCTCATCCAGAAACAGATATTCAAGATCTTCTATGCTCTT GTTCAGTATACACTACCACTGGAACTGATAAACCAACAGAACCTGACAGAATGGATAGAAATTTTAAAGACTGTTGTGAACAGGGATGTA CCTAATGAAACACTTCAAGTTGAAGAAGATGATCGACCTGAGTTACCATGGTGGAAATGCAAGAAGTGGGCCTTACATATTTTAGCAAGA CTTTTTGAAAGATATGGAAGCCCTGGCAATGTTTCCAAGGAGTATAATGAATTTGCTGAAGTATTTCTGAAGGCATTTGCTGTTGGTGTC CAGCAAAAATATTATTCATCTGTGCCAGAGGAAGGAGGGGCAACCCATGTCTATCGTTATCACAGAGGCGAGTCGAAGCTGCACATGTGC TTGGACATAGGGAATGGTCAGAGAAAAGACAGAAAAAAGACATCCCTTGGTCCTGGAGGCAGCTATCAAATATCAGAGCATGCTCCAGAG GCATCCCAGCCTGCTGAGAACATCTCTAAGGACCTCTACATAGAAGTATATCCAGGGACCTATTCTGTCACTGTGGGCTCAAATGACTTA >In-frame_IPO7_ENST00000379719_chr11_9442245_+_AKIP1_ENST00000534147_chr11_8936373_+_1236nt ATGGACCCCAACACCATTATCGAGGCCCTGCGGGGCACTATGGACCCAGCCCTGCGTGAGGCCGCGGAGCGCCAGCTCAATGAAGCACAC AAGTCTCTGAATTTTGTCTCAACACTGCTCCAGATTACTATGTCGGAACAGCTGGATTTACCTGTGAGACAGGCAGGTGTTATCTATCTG AAAAATATGATAACACAGTATTGGCCTGATCGAGAAACAGCACCAGGGGATATATCCCCTTATACTATTCCAGAAGAAGATCGCCATTGT ATTCGAGAAAATATTGTAGAAGCCATTATCCATTCTCCTGAGCTCATCAGGGTACAGCTTACTACATGCATTCATCACATCATCAAACAT GATTATCCAAGCCGCTGGACTGCCATTGTGGACAAAATTGGCTTTTATCTTCAGTCCGATAACAGTGCTTGTTGGCTAGGAATTCTTCTT TGCCTTTATCAGCTTGTGAAAAATTATGAGTATAAAAAACCAGAGGAGCGGAGTCCATTGGTAGCAGCAATGCAGCATTTTCTGCCAGTT CTAAAGGATCGTTTTATCCAGCTTCTTTCTGACCAGTCTGATCAGTCTGTCCTCATCCAGAAACAGATATTCAAGATCTTCTATGCTCTT GTTCAGTATACACTACCACTGGAACTGATAAACCAACAGAACCTGACAGAATGGATAGAAATTTTAAAGACTGTTGTGAACAGGGATGTA CCTAATGAAACACTTCAAGTTGAAGAAGATGATCGACCTGAGTTACCATGGTGGAAATGCAAGAAGTGGGCCTTACATATTTTAGCAAGA CTTTTTGAAAGATATGGAAGCCCTGGCAATGTTTCCAAGGAGTATAATGAATTTGCTGAAGTATTTCTGAAGGCATTTGCTGTTGGTGTC CAGCAAAAATATTATTCATCTGTGCCAGAGGAAGGAGGGGCAACCCATGTCTATCGTTATCACAGAGGCGAGTCGAAGCTGCACATGTGC TTGGACATAGGGAATGGTCAGAGAAAAGACAGAAAAAAGACATCCCTTGGTCCTGGAGGCAGCTATCAAATATCAGAGCATGCTCCAGAG GCATCCCAGCCTGCTGAGAACATCTCTAAGGACCTCTACATAGAAGTATATCCAGGGACCTATTCTGTCACTGTGGGCTCAAATGACTTA |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_IPO7_ENST00000379719_chr11_9442245_+_AKIP1_ENST00000299576_chr11_8936373_+_1982nt GTTCTATCCGGGGCCTTGGCGCTTCTCTTTCCTTTCGCGCCGGTTGCCGCTGCGGAGCGCGGCGGGTCCATGTGCGCAGTGAGTGGCGCT ATTCCTGGCCCAGTAGCACCCGAGCCCCGGGTTTGACCGAGTCCGCGCTGCGATGGACCCCAACACCATTATCGAGGCCCTGCGGGGCAC TATGGACCCAGCCCTGCGTGAGGCCGCGGAGCGCCAGCTCAATGAAGCACACAAGTCTCTGAATTTTGTCTCAACACTGCTCCAGATTAC TATGTCGGAACAGCTGGATTTACCTGTGAGACAGGCAGGTGTTATCTATCTGAAAAATATGATAACACAGTATTGGCCTGATCGAGAAAC AGCACCAGGGGATATATCCCCTTATACTATTCCAGAAGAAGATCGCCATTGTATTCGAGAAAATATTGTAGAAGCCATTATCCATTCTCC TGAGCTCATCAGGGTACAGCTTACTACATGCATTCATCACATCATCAAACATGATTATCCAAGCCGCTGGACTGCCATTGTGGACAAAAT TGGCTTTTATCTTCAGTCCGATAACAGTGCTTGTTGGCTAGGAATTCTTCTTTGCCTTTATCAGCTTGTGAAAAATTATGAGTATAAAAA ACCAGAGGAGCGGAGTCCATTGGTAGCAGCAATGCAGCATTTTCTGCCAGTTCTAAAGGATCGTTTTATCCAGCTTCTTTCTGACCAGTC TGATCAGTCTGTCCTCATCCAGAAACAGATATTCAAGATCTTCTATGCTCTTGTTCAGTATACACTACCACTGGAACTGATAAACCAACA GAACCTGACAGAATGGATAGAAATTTTAAAGACTGTTGTGAACAGGGATGTACCTAATGAAACACTTCAAGTTGAAGAAGATGATCGACC TGAGTTACCATGGTGGAAATGCAAGAAGTGGGCCTTACATATTTTAGCAAGACTTTTTGAAAGATATGGAAGCCCTGGCAATGTTTCCAA GGAGTATAATGAATTTGCTGAAGTATTTCTGAAGGCATTTGCTGTTGGTGTCCAGCAAAAATATTATTCATCTGTGCCAGAGGAAGGAGG GGCAACCCATGTCTATCGTTATCACAGAGGCGAGTCGAAGCTGCACATGTGCTTGGACATAGGGAATGGTCAGAGAAAAGACAGAAAAAA GACATCCCTTGGTCCTGGAGGCAGCTATCAAATATCAGAGCATGCTCCAGAGGCATCCCAGCCTGCTGAGAACATCTCTAAGGACCTCTA CATAGAAGTATATCCAGGGACCTATTCTGTCACTGTGGGCTCAAATGACTTAACCAAGAAGACTCATGTGGTAGCAGTTGATTCTGGACA AAGCGTGGACCTGGTCTTCCCTGTGTGATGTTGACCATCACTGCCATCACATCACCTTTTTTTAAGTAGTAAGAATAAAGCCACTGTATG ATTCTCTTAATAGCTATACATTAATCCTGTTTTTAGTGCTGACTGGGTCAGCCTTCCGGGAACTGGAGTCTGTCTCTTTCAGTGCTTTTT TGTTTGTTTGGTTGGTTTTTTTTTGAGACAGTCTCACTCTGTTGCCCAGGCTGGAGTGCAGTGGCGTGATCTCGGCTCACTGCAAGTTCC GCCTCCCGGGTTCACACCATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGCACTACAGGCACCCGCCACCATGCCCGGCTATTTTTTTTGT ATTTTTAGTAGAGACGGGGTTTCACCATGTTGGCCAGGATGGTCTCGATCTCTTGACCTCGTGATCCACCCACCTTGGCCTCCCAAAGTG TTGGGATTACAGGCGTGAGCCACCGCGCCCGGCCTCAGTGCCTTTTTTAACTTGAGGGTGTAGAGGTCCTCCACGCTTGTTTGCCTGAAA GTAATATAATGATGCTGTCTGAACAGGTTTTACTGCTTGCTTTCCAAGTAAAGGTTAATTATGATAATAAAGAGATTTGGAAATGAAGAG >In-frame_IPO7_ENST00000379719_chr11_9442245_+_AKIP1_ENST00000309377_chr11_8936373_+_1982nt GTTCTATCCGGGGCCTTGGCGCTTCTCTTTCCTTTCGCGCCGGTTGCCGCTGCGGAGCGCGGCGGGTCCATGTGCGCAGTGAGTGGCGCT ATTCCTGGCCCAGTAGCACCCGAGCCCCGGGTTTGACCGAGTCCGCGCTGCGATGGACCCCAACACCATTATCGAGGCCCTGCGGGGCAC TATGGACCCAGCCCTGCGTGAGGCCGCGGAGCGCCAGCTCAATGAAGCACACAAGTCTCTGAATTTTGTCTCAACACTGCTCCAGATTAC TATGTCGGAACAGCTGGATTTACCTGTGAGACAGGCAGGTGTTATCTATCTGAAAAATATGATAACACAGTATTGGCCTGATCGAGAAAC AGCACCAGGGGATATATCCCCTTATACTATTCCAGAAGAAGATCGCCATTGTATTCGAGAAAATATTGTAGAAGCCATTATCCATTCTCC TGAGCTCATCAGGGTACAGCTTACTACATGCATTCATCACATCATCAAACATGATTATCCAAGCCGCTGGACTGCCATTGTGGACAAAAT TGGCTTTTATCTTCAGTCCGATAACAGTGCTTGTTGGCTAGGAATTCTTCTTTGCCTTTATCAGCTTGTGAAAAATTATGAGTATAAAAA ACCAGAGGAGCGGAGTCCATTGGTAGCAGCAATGCAGCATTTTCTGCCAGTTCTAAAGGATCGTTTTATCCAGCTTCTTTCTGACCAGTC TGATCAGTCTGTCCTCATCCAGAAACAGATATTCAAGATCTTCTATGCTCTTGTTCAGTATACACTACCACTGGAACTGATAAACCAACA GAACCTGACAGAATGGATAGAAATTTTAAAGACTGTTGTGAACAGGGATGTACCTAATGAAACACTTCAAGTTGAAGAAGATGATCGACC TGAGTTACCATGGTGGAAATGCAAGAAGTGGGCCTTACATATTTTAGCAAGACTTTTTGAAAGATATGGAAGCCCTGGCAATGTTTCCAA GGAGTATAATGAATTTGCTGAAGTATTTCTGAAGGCATTTGCTGTTGGTGTCCAGCAAAAATATTATTCATCTGTGCCAGAGGAAGGAGG GGCAACCCATGTCTATCGTTATCACAGAGGCGAGTCGAAGCTGCACATGTGCTTGGACATAGGGAATGGTCAGAGAAAAGACAGAAAAAA GACATCCCTTGGTCCTGGAGGCAGCTATCAAATATCAGAGCATGCTCCAGAGGCATCCCAGCCTGCTGAGAACATCTCTAAGGACCTCTA CATAGAAGTATATCCAGGGACCTATTCTGTCACTGTGGGCTCAAATGACTTAACCAAGAAGACTCATGTGGTAGCAGTTGATTCTGGACA AAGCGTGGACCTGGTCTTCCCTGTGTGATGTTGACCATCACTGCCATCACATCACCTTTTTTTAAGTAGTAAGAATAAAGCCACTGTATG ATTCTCTTAATAGCTATACATTAATCCTGTTTTTAGTGCTGACTGGGTCAGCCTTCCGGGAACTGGAGTCTGTCTCTTTCAGTGCTTTTT TGTTTGTTTGGTTGGTTTTTTTTTGAGACAGTCTCACTCTGTTGCCCAGGCTGGAGTGCAGTGGCGTGATCTCGGCTCACTGCAAGTTCC GCCTCCCGGGTTCACACCATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGCACTACAGGCACCCGCCACCATGCCCGGCTATTTTTTTTGT ATTTTTAGTAGAGACGGGGTTTCACCATGTTGGCCAGGATGGTCTCGATCTCTTGACCTCGTGATCCACCCACCTTGGCCTCCCAAAGTG TTGGGATTACAGGCGTGAGCCACCGCGCCCGGCCTCAGTGCCTTTTTTAACTTGAGGGTGTAGAGGTCCTCCACGCTTGTTTGCCTGAAA GTAATATAATGATGCTGTCTGAACAGGTTTTACTGCTTGCTTTCCAAGTAAAGGTTAATTATGATAATAAAGAGATTTGGAAATGAAGAG >In-frame_IPO7_ENST00000379719_chr11_9442245_+_AKIP1_ENST00000309357_chr11_8936373_+_1901nt GTTCTATCCGGGGCCTTGGCGCTTCTCTTTCCTTTCGCGCCGGTTGCCGCTGCGGAGCGCGGCGGGTCCATGTGCGCAGTGAGTGGCGCT ATTCCTGGCCCAGTAGCACCCGAGCCCCGGGTTTGACCGAGTCCGCGCTGCGATGGACCCCAACACCATTATCGAGGCCCTGCGGGGCAC TATGGACCCAGCCCTGCGTGAGGCCGCGGAGCGCCAGCTCAATGAAGCACACAAGTCTCTGAATTTTGTCTCAACACTGCTCCAGATTAC TATGTCGGAACAGCTGGATTTACCTGTGAGACAGGCAGGTGTTATCTATCTGAAAAATATGATAACACAGTATTGGCCTGATCGAGAAAC AGCACCAGGGGATATATCCCCTTATACTATTCCAGAAGAAGATCGCCATTGTATTCGAGAAAATATTGTAGAAGCCATTATCCATTCTCC TGAGCTCATCAGGGTACAGCTTACTACATGCATTCATCACATCATCAAACATGATTATCCAAGCCGCTGGACTGCCATTGTGGACAAAAT TGGCTTTTATCTTCAGTCCGATAACAGTGCTTGTTGGCTAGGAATTCTTCTTTGCCTTTATCAGCTTGTGAAAAATTATGAGTATAAAAA ACCAGAGGAGCGGAGTCCATTGGTAGCAGCAATGCAGCATTTTCTGCCAGTTCTAAAGGATCGTTTTATCCAGCTTCTTTCTGACCAGTC TGATCAGTCTGTCCTCATCCAGAAACAGATATTCAAGATCTTCTATGCTCTTGTTCAGTATACACTACCACTGGAACTGATAAACCAACA GAACCTGACAGAATGGATAGAAATTTTAAAGACTGTTGTGAACAGGGATGTACCTAATGAAACACTTCAAGTTGAAGAAGATGATCGACC TGAGTTACCATGGTGGAAATGCAAGAAGTGGGCCTTACATATTTTAGCAAGACTTTTTGAAAGATATGGAAGCCCTGGCAATGTTTCCAA GGAGTATAATGAATTTGCTGAAGTATTTCTGAAGGCATTTGCTGTTGGTGTCCAGCAAAAATATTATTCATCTGTGCCAGAGGAAGGAGG GGCAACCCATGTCTATCGTTATCACAGAGGCGAGTCGAAGCTGCACATGTGCTTGGACATAGGGAATGGTCAGGCTGAGAACATCTCTAA GGACCTCTACATAGAAGTATATCCAGGGACCTATTCTGTCACTGTGGGCTCAAATGACTTAACCAAGAAGACTCATGTGGTAGCAGTTGA TTCTGGACAAAGCGTGGACCTGGTCTTCCCTGTGTGATGTTGACCATCACTGCCATCACATCACCTTTTTTTAAGTAGTAAGAATAAAGC CACTGTATGATTCTCTTAATAGCTATACATTAATCCTGTTTTTAGTGCTGACTGGGTCAGCCTTCCGGGAACTGGAGTCTGTCTCTTTCA GTGCTTTTTTGTTTGTTTGGTTGGTTTTTTTTTGAGACAGTCTCACTCTGTTGCCCAGGCTGGAGTGCAGTGGCGTGATCTCGGCTCACT GCAAGTTCCGCCTCCCGGGTTCACACCATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGCACTACAGGCACCCGCCACCATGCCCGGCTAT TTTTTTTGTATTTTTAGTAGAGACGGGGTTTCACCATGTTGGCCAGGATGGTCTCGATCTCTTGACCTCGTGATCCACCCACCTTGGCCT CCCAAAGTGTTGGGATTACAGGCGTGAGCCACCGCGCCCGGCCTCAGTGCCTTTTTTAACTTGAGGGTGTAGAGGTCCTCCACGCTTGTT TGCCTGAAAGTAATATAATGATGCTGTCTGAACAGGTTTTACTGCTTGCTTTCCAAGTAAAGGTTAATTATGATAATAAAGAGATTTGGA >In-frame_IPO7_ENST00000379719_chr11_9442245_+_AKIP1_ENST00000529876_chr11_8936373_+_1986nt GTTCTATCCGGGGCCTTGGCGCTTCTCTTTCCTTTCGCGCCGGTTGCCGCTGCGGAGCGCGGCGGGTCCATGTGCGCAGTGAGTGGCGCT ATTCCTGGCCCAGTAGCACCCGAGCCCCGGGTTTGACCGAGTCCGCGCTGCGATGGACCCCAACACCATTATCGAGGCCCTGCGGGGCAC TATGGACCCAGCCCTGCGTGAGGCCGCGGAGCGCCAGCTCAATGAAGCACACAAGTCTCTGAATTTTGTCTCAACACTGCTCCAGATTAC TATGTCGGAACAGCTGGATTTACCTGTGAGACAGGCAGGTGTTATCTATCTGAAAAATATGATAACACAGTATTGGCCTGATCGAGAAAC AGCACCAGGGGATATATCCCCTTATACTATTCCAGAAGAAGATCGCCATTGTATTCGAGAAAATATTGTAGAAGCCATTATCCATTCTCC TGAGCTCATCAGGGTACAGCTTACTACATGCATTCATCACATCATCAAACATGATTATCCAAGCCGCTGGACTGCCATTGTGGACAAAAT TGGCTTTTATCTTCAGTCCGATAACAGTGCTTGTTGGCTAGGAATTCTTCTTTGCCTTTATCAGCTTGTGAAAAATTATGAGTATAAAAA ACCAGAGGAGCGGAGTCCATTGGTAGCAGCAATGCAGCATTTTCTGCCAGTTCTAAAGGATCGTTTTATCCAGCTTCTTTCTGACCAGTC TGATCAGTCTGTCCTCATCCAGAAACAGATATTCAAGATCTTCTATGCTCTTGTTCAGTATACACTACCACTGGAACTGATAAACCAACA GAACCTGACAGAATGGATAGAAATTTTAAAGACTGTTGTGAACAGGGATGTACCTAATGAAACACTTCAAGTTGAAGAAGATGATCGACC TGAGTTACCATGGTGGAAATGCAAGAAGTGGGCCTTACATATTTTAGCAAGACTTTTTGAAAGATATGGAAGCCCTGGCAATGTTTCCAA GGAGTATAATGAATTTGCTGAAGTATTTCTGAAGGCATTTGCTGTTGGTGTCCAGCAAAAATATTATTCATCTGTGCCAGAGGAAGGAGG GGCAACCCATGTCTATCGTTATCACAGAGGCGAGTCGAAGCTGCACATGTGCTTGGACATAGGGAATGGTCAGAGAAAAGACAGAAAAAA GACATCCCTTGGTCCTGGAGGCAGCTATCAAATATCAGAGCATGCTCCAGAGGCATCCCAGCCTGTGAGTACGGAACTGCTTACGCACTG GGTTTCACCACCGTTGCAACTCCATGAACCAGTTGACATGGTTCTTAGAGGGCTATTTGAATTGAGTCTATAGTATTTTTAAGTTGAGAT GTTCTTACACTTAAGAAGGGCACACAAGATTTTGGTTCAGTGTAAAATTAGGTTTTCTTGGTATTCTTCCTTCACTCTAAGCTTCAGGGA TACTCTTTGTGCCTGAACTCATAGTTGTGGTTGGAAAGAATGTGAAGTATTCACCTCTCAGTTCCTACAGCTCAGCTGGGCTGGCACTGG GTCCTGCTGGAATTCCACCATCTGTTCAAGCAGCAGGAGGGGCACGATCCTCCTGCTAACAAAGTGAAAACCATTGCTGAAATTCCGAAA CATACACATTTGGTGAGATCAGGTTCCAAAACATTTGAAGGCATTTGTTCTTATTTTCCACAAATGTTTCTCTGTAAAAACATATAATGA GTTTTTCATTTTTAGGATAAAGTACTCATTAGGTCATGAAGCCAGGGGATCCTTTTTGGAACTTGGAAGGGCTAGAATTCTGAGGAAAGG AACTTCATTCAGCATGGTGCCGCAATACATTTACTTTTTGTTTGTATACGGTTTGCTACGAGTCAGGATTTGGAGTATACTAGAGTTAGT GACAATTAAGAATATTCTGCTTCTAGTACAAATATAAGTTGTTAAGGCTTAGACGCCTCTCAACACTTGCTGACTTTTGGTAATGCTGAT >In-frame_IPO7_ENST00000379719_chr11_9442245_+_AKIP1_ENST00000525005_chr11_8936373_+_1615nt GTTCTATCCGGGGCCTTGGCGCTTCTCTTTCCTTTCGCGCCGGTTGCCGCTGCGGAGCGCGGCGGGTCCATGTGCGCAGTGAGTGGCGCT ATTCCTGGCCCAGTAGCACCCGAGCCCCGGGTTTGACCGAGTCCGCGCTGCGATGGACCCCAACACCATTATCGAGGCCCTGCGGGGCAC TATGGACCCAGCCCTGCGTGAGGCCGCGGAGCGCCAGCTCAATGAAGCACACAAGTCTCTGAATTTTGTCTCAACACTGCTCCAGATTAC TATGTCGGAACAGCTGGATTTACCTGTGAGACAGGCAGGTGTTATCTATCTGAAAAATATGATAACACAGTATTGGCCTGATCGAGAAAC AGCACCAGGGGATATATCCCCTTATACTATTCCAGAAGAAGATCGCCATTGTATTCGAGAAAATATTGTAGAAGCCATTATCCATTCTCC TGAGCTCATCAGGGTACAGCTTACTACATGCATTCATCACATCATCAAACATGATTATCCAAGCCGCTGGACTGCCATTGTGGACAAAAT TGGCTTTTATCTTCAGTCCGATAACAGTGCTTGTTGGCTAGGAATTCTTCTTTGCCTTTATCAGCTTGTGAAAAATTATGAGTATAAAAA ACCAGAGGAGCGGAGTCCATTGGTAGCAGCAATGCAGCATTTTCTGCCAGTTCTAAAGGATCGTTTTATCCAGCTTCTTTCTGACCAGTC TGATCAGTCTGTCCTCATCCAGAAACAGATATTCAAGATCTTCTATGCTCTTGTTCAGTATACACTACCACTGGAACTGATAAACCAACA GAACCTGACAGAATGGATAGAAATTTTAAAGACTGTTGTGAACAGGGATGTACCTAATGAAACACTTCAAGTTGAAGAAGATGATCGACC TGAGTTACCATGGTGGAAATGCAAGAAGTGGGCCTTACATATTTTAGCAAGACTTTTTGAAAGATATGGAAGCCCTGGCAATGTTTCCAA GGAGTATAATGAATTTGCTGAAGTATTTCTGAAGGCATTTGCTGTTGGTGTCCAGCAAAAATATTATTCATCTGTGCCAGAGGAAGGAGG GGCAACCCATGTCTATCGTTATCACAGAGGCGAGTCGAAGCTGCACATGTGCTTGGACATAGGGAATGGTCAGAGAAAAGACAGAAAAAA GACATCCCTTGGTCCTGGAGGCAGCTATCAAATATCAGAGCATGCTCCAGAGGCATCCCAGCCTGTGAGTACGGAACTGCTTACGCACTG GGTTTCACCACCGTTGCAACTCCATGAACCAGTTGACATGGTTCTTAGAGGGCTATTTGAATTGAGTCTATAGTATTTTTAAGTTGAGAT GTTCTTACACTTAAGAAGGGCACACAAGATTTTGGTTCAGTGTAAAATTAGGTTTTCTTGGTATTCTTCCTTCACTCTAAGCTTCAGGGA TACTCTTTGTGCCTGAACTCATAGTTGTGGTTGGAAAGAATGTGAAGTATTCACCTCTCAGTTCCTACAGCTCAGCTGGGCTGGCACTGG >In-frame_IPO7_ENST00000379719_chr11_9442245_+_AKIP1_ENST00000534506_chr11_8936373_+_1371nt GTTCTATCCGGGGCCTTGGCGCTTCTCTTTCCTTTCGCGCCGGTTGCCGCTGCGGAGCGCGGCGGGTCCATGTGCGCAGTGAGTGGCGCT ATTCCTGGCCCAGTAGCACCCGAGCCCCGGGTTTGACCGAGTCCGCGCTGCGATGGACCCCAACACCATTATCGAGGCCCTGCGGGGCAC TATGGACCCAGCCCTGCGTGAGGCCGCGGAGCGCCAGCTCAATGAAGCACACAAGTCTCTGAATTTTGTCTCAACACTGCTCCAGATTAC TATGTCGGAACAGCTGGATTTACCTGTGAGACAGGCAGGTGTTATCTATCTGAAAAATATGATAACACAGTATTGGCCTGATCGAGAAAC AGCACCAGGGGATATATCCCCTTATACTATTCCAGAAGAAGATCGCCATTGTATTCGAGAAAATATTGTAGAAGCCATTATCCATTCTCC TGAGCTCATCAGGGTACAGCTTACTACATGCATTCATCACATCATCAAACATGATTATCCAAGCCGCTGGACTGCCATTGTGGACAAAAT TGGCTTTTATCTTCAGTCCGATAACAGTGCTTGTTGGCTAGGAATTCTTCTTTGCCTTTATCAGCTTGTGAAAAATTATGAGTATAAAAA ACCAGAGGAGCGGAGTCCATTGGTAGCAGCAATGCAGCATTTTCTGCCAGTTCTAAAGGATCGTTTTATCCAGCTTCTTTCTGACCAGTC TGATCAGTCTGTCCTCATCCAGAAACAGATATTCAAGATCTTCTATGCTCTTGTTCAGTATACACTACCACTGGAACTGATAAACCAACA GAACCTGACAGAATGGATAGAAATTTTAAAGACTGTTGTGAACAGGGATGTACCTAATGAAACACTTCAAGTTGAAGAAGATGATCGACC TGAGTTACCATGGTGGAAATGCAAGAAGTGGGCCTTACATATTTTAGCAAGACTTTTTGAAAGATATGGAAGCCCTGGCAATGTTTCCAA GGAGTATAATGAATTTGCTGAAGTATTTCTGAAGGCATTTGCTGTTGGTGTCCAGCAAAAATATTATTCATCTGTGCCAGAGGAAGGAGG GGCAACCCATGTCTATCGTTATCACAGAGGCGAGTCGAAGCTGCACATGTGCTTGGACATAGGGAATGGTCAGAGAAAAGACAGAAAAAA GACATCCCTTGGTCCTGGAGGCAGCTATCAAATATCAGAGCATGCTCCAGAGGCATCCCAGCCTGTGAGTACGGAACTGCTTACGCACTG GGTTTCACCACCGTTGCAACTCCATGAACCAGTTGACATGGTTCTTAGAGGGCTATTTGAATTGAGTCTATAGTATTTTTAAGTTGAGAT >In-frame_IPO7_ENST00000379719_chr11_9442245_+_AKIP1_ENST00000396648_chr11_8936373_+_1798nt GTTCTATCCGGGGCCTTGGCGCTTCTCTTTCCTTTCGCGCCGGTTGCCGCTGCGGAGCGCGGCGGGTCCATGTGCGCAGTGAGTGGCGCT ATTCCTGGCCCAGTAGCACCCGAGCCCCGGGTTTGACCGAGTCCGCGCTGCGATGGACCCCAACACCATTATCGAGGCCCTGCGGGGCAC TATGGACCCAGCCCTGCGTGAGGCCGCGGAGCGCCAGCTCAATGAAGCACACAAGTCTCTGAATTTTGTCTCAACACTGCTCCAGATTAC TATGTCGGAACAGCTGGATTTACCTGTGAGACAGGCAGGTGTTATCTATCTGAAAAATATGATAACACAGTATTGGCCTGATCGAGAAAC AGCACCAGGGGATATATCCCCTTATACTATTCCAGAAGAAGATCGCCATTGTATTCGAGAAAATATTGTAGAAGCCATTATCCATTCTCC TGAGCTCATCAGGGTACAGCTTACTACATGCATTCATCACATCATCAAACATGATTATCCAAGCCGCTGGACTGCCATTGTGGACAAAAT TGGCTTTTATCTTCAGTCCGATAACAGTGCTTGTTGGCTAGGAATTCTTCTTTGCCTTTATCAGCTTGTGAAAAATTATGAGTATAAAAA ACCAGAGGAGCGGAGTCCATTGGTAGCAGCAATGCAGCATTTTCTGCCAGTTCTAAAGGATCGTTTTATCCAGCTTCTTTCTGACCAGTC TGATCAGTCTGTCCTCATCCAGAAACAGATATTCAAGATCTTCTATGCTCTTGTTCAGTATACACTACCACTGGAACTGATAAACCAACA GAACCTGACAGAATGGATAGAAATTTTAAAGACTGTTGTGAACAGGGATGTACCTAATGAAACACTTCAAGTTGAAGAAGATGATCGACC TGAGTTACCATGGTGGAAATGCAAGAAGTGGGCCTTACATATTTTAGCAAGACTTTTTGAAAGATATGGAAGCCCTGGCAATGTTTCCAA GGAGTATAATGAATTTGCTGAAGTATTTCTGAAGGCATTTGCTGTTGGTGTCCAGCAAAAATATTATTCATCTGTGCCAGAGGAAGGAGG GGCAACCCATGTCTATCGTTATCACAGAGGCGAGTCGAAGCTGCACATGTGCTTGGACATAGGGAATGGTCAGAGAAAAGACAGAAAAAA GACATCCCTTGGTCCTGGAGGCAGCTATCAAATATCAGAGCATGCTCCAGAGGCATCCCAGCCTGCTGAGAACATCTCTAAGGACCTCTA CATAGAAGTATATCCAGGGACCTATTCTGTCACTGTGGGCTCAAATGACTTAACCAAGAAGACTCATGTGGTAGCAGTTGATTCTGGACA AAGCGTGGACCTGGTCTTCCCTGTGTGATGTTGACCATCACTGCCATCACATCACCTTTTTTTAAGTAGTAAGAATAAAGCCACTGTATG ATTCTCTTAATAGCTATACATTAATCCTGTTTTTAGTGCTGACTGGGTCAGCCTTCCGGGAACTGGAGTCTGTCTCTTTCAGTGCTTTTT TGTTTGTTTGGTTGGTTTTTTTTTGAGACAGTCTCACTCTGTTGCCCAGGCTGGAGTGCAGTGGCGTGATCTCGGCTCACTGCAAGTTCC GCCTCCCGGGTTCACACCATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGCACTACAGGCACCCGCCACCATGCCCGGCTATTTTTTTTGT >In-frame_IPO7_ENST00000379719_chr11_9442245_+_AKIP1_ENST00000534147_chr11_8936373_+_1760nt GTTCTATCCGGGGCCTTGGCGCTTCTCTTTCCTTTCGCGCCGGTTGCCGCTGCGGAGCGCGGCGGGTCCATGTGCGCAGTGAGTGGCGCT ATTCCTGGCCCAGTAGCACCCGAGCCCCGGGTTTGACCGAGTCCGCGCTGCGATGGACCCCAACACCATTATCGAGGCCCTGCGGGGCAC TATGGACCCAGCCCTGCGTGAGGCCGCGGAGCGCCAGCTCAATGAAGCACACAAGTCTCTGAATTTTGTCTCAACACTGCTCCAGATTAC TATGTCGGAACAGCTGGATTTACCTGTGAGACAGGCAGGTGTTATCTATCTGAAAAATATGATAACACAGTATTGGCCTGATCGAGAAAC AGCACCAGGGGATATATCCCCTTATACTATTCCAGAAGAAGATCGCCATTGTATTCGAGAAAATATTGTAGAAGCCATTATCCATTCTCC TGAGCTCATCAGGGTACAGCTTACTACATGCATTCATCACATCATCAAACATGATTATCCAAGCCGCTGGACTGCCATTGTGGACAAAAT TGGCTTTTATCTTCAGTCCGATAACAGTGCTTGTTGGCTAGGAATTCTTCTTTGCCTTTATCAGCTTGTGAAAAATTATGAGTATAAAAA ACCAGAGGAGCGGAGTCCATTGGTAGCAGCAATGCAGCATTTTCTGCCAGTTCTAAAGGATCGTTTTATCCAGCTTCTTTCTGACCAGTC TGATCAGTCTGTCCTCATCCAGAAACAGATATTCAAGATCTTCTATGCTCTTGTTCAGTATACACTACCACTGGAACTGATAAACCAACA GAACCTGACAGAATGGATAGAAATTTTAAAGACTGTTGTGAACAGGGATGTACCTAATGAAACACTTCAAGTTGAAGAAGATGATCGACC TGAGTTACCATGGTGGAAATGCAAGAAGTGGGCCTTACATATTTTAGCAAGACTTTTTGAAAGATATGGAAGCCCTGGCAATGTTTCCAA GGAGTATAATGAATTTGCTGAAGTATTTCTGAAGGCATTTGCTGTTGGTGTCCAGCAAAAATATTATTCATCTGTGCCAGAGGAAGGAGG GGCAACCCATGTCTATCGTTATCACAGAGGCGAGTCGAAGCTGCACATGTGCTTGGACATAGGGAATGGTCAGAGAAAAGACAGAAAAAA GACATCCCTTGGTCCTGGAGGCAGCTATCAAATATCAGAGCATGCTCCAGAGGCATCCCAGCCTGCTGAGAACATCTCTAAGGACCTCTA CATAGAAGTATATCCAGGGACCTATTCTGTCACTGTGGGCTCAAATGACTTAACCAAGAAGACTCATGTGGTAGCAGTTGATTCTGGACA AAGCGTGGACCTGGTCTTCCCTGTGTGATGTTGACCATCACTGCCATCACATCACCTTTTTTTAAGTAGTAAGAATAAAGCCACTGTATG ATTCTCTTAATAGCTATACATTAATCCTGTTTTTAGTGCTGACTGGGTCAGCCTTCCGGGAACTGGAGTCTGTCTCTTTCAGTGCTTTTT TGTTTGTTTGGTTGGTTTTTTTTTGAGACAGTCTCACTCTGTTGCCCAGGCTGGAGTGCAGTGGCGTGATCTCGGCTCACTGCAAGTTCC GCCTCCCGGGTTCACACCATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGCACTACAGGCACCCGCCACCATGCCCGGCTATTTTTTTTGT |
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FusionGenePPI for IPO7_AKIP1 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| IPO7 | SRP19, RPL23A, KPNB1, USP49, AIRE, UBC, MYC, RNF146, RAN, SIRT7, FBXO25, CDK2, IGBP1, CA9, METTL18, CFTR, SOX2, EGFR, FBXO6, APEH, CAND1, ELAC2, HARS, HSPA1L, HSPA4L, KARS, NFRKB, PFDN5, RNASEH2A, TNPO1, TRMT112, STAU1, MDM2, CCDC8, RNF2, ILK, RIC3, NUSAP1, VTI1B, COMTD1, CD274, TNFSF13B, ZBTB38, VSIG2, PNKD, RP2, EDA, PTGER3, RPS6KB2, UNK, HSP90AB1, HSPA8, HSPB1, IPO5, IPO9, SLC25A3, MPHOSPH10, PPM1G, NTRK1, IFI16, CEP162, LCA5, RPGRIP1L, SSX2IP, SPICE1, DCTN1, CEP19, RPGRIP1, CAPZA2, MAD2L1, NUP153, HDAC6, LIMA1, NUP107, VPS16, ASPM, MCM2, CDC5L, DUSP5, SIGLECL1, HP1BP3, AURKAIP1, FZD10, TMEM206, HTR2C, UXS1, CHRM3, PTPRE, TRIM25, G3BP1, BRCA1, TES | AKIP1 | PRKACA, RELA, SIRT1, SENP8, MAPK13, ELAVL1, BARD1, POC5, POC1A, CNOT2, RNF2, SPTAN1, MCPH1 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for IPO7_AKIP1 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for IPO7_AKIP1 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | IPO7 | C0019693 | HIV Infections | 1 | CTD_human |
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