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Fusion gene ID: 17631 |
FusionGeneSummary for IPO11_TNFAIP8 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: IPO11_TNFAIP8 | Fusion gene ID: 17631 | Hgene | Tgene | Gene symbol | IPO11 | TNFAIP8 | Gene ID | 51194 | 25816 |
| Gene name | importin 11 | TNF alpha induced protein 8 | |
| Synonyms | RanBP11 | GG2-1|MDC-3.13|NDED|SCC-S2|SCCS2 | |
| Cytomap | 5q12.1 | 5q23.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | importin-11Ran binding protein 11imp11ran-binding protein 11 | tumor necrosis factor alpha-induced protein 8NF-kappa-B-inducible DED-containing proteinTNF-induced protein GG2-1head and neck tumor and metastasis-related proteintumor necrosis factor, alpha induced protein 8 | |
| Modification date | 20180523 | 20180523 | |
| UniProtAcc | Q9UI26 | O95379 | |
| Ensembl transtripts involved in fusion gene | ENST00000325324, ENST00000409296, ENST00000409534, ENST00000512177, | ENST00000274456, ENST00000513374, ENST00000504771, ENST00000503646, ENST00000504642, ENST00000415806, | |
| Fusion gene scores | * DoF score | 6 X 6 X 4=144 | 5 X 4 X 4=80 |
| # samples | 6 | 6 | |
| ** MAII score | log2(6/144*10)=-1.26303440583379 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(6/80*10)=-0.415037499278844 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: IPO11 [Title/Abstract] AND TNFAIP8 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | BRCA | TCGA-A8-A08L-01A | IPO11 | chr5 | 61770291 | + | TNFAIP8 | chr5 | 118728511 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| Frame-shift | ENST00000325324 | ENST00000274456 | IPO11 | chr5 | 61770291 | + | TNFAIP8 | chr5 | 118728511 | + |
| In-frame | ENST00000325324 | ENST00000513374 | IPO11 | chr5 | 61770291 | + | TNFAIP8 | chr5 | 118728511 | + |
| Frame-shift | ENST00000325324 | ENST00000504771 | IPO11 | chr5 | 61770291 | + | TNFAIP8 | chr5 | 118728511 | + |
| In-frame | ENST00000325324 | ENST00000503646 | IPO11 | chr5 | 61770291 | + | TNFAIP8 | chr5 | 118728511 | + |
| In-frame | ENST00000325324 | ENST00000504642 | IPO11 | chr5 | 61770291 | + | TNFAIP8 | chr5 | 118728511 | + |
| 5CDS-3UTR | ENST00000325324 | ENST00000415806 | IPO11 | chr5 | 61770291 | + | TNFAIP8 | chr5 | 118728511 | + |
| Frame-shift | ENST00000409296 | ENST00000274456 | IPO11 | chr5 | 61770291 | + | TNFAIP8 | chr5 | 118728511 | + |
| In-frame | ENST00000409296 | ENST00000513374 | IPO11 | chr5 | 61770291 | + | TNFAIP8 | chr5 | 118728511 | + |
| Frame-shift | ENST00000409296 | ENST00000504771 | IPO11 | chr5 | 61770291 | + | TNFAIP8 | chr5 | 118728511 | + |
| In-frame | ENST00000409296 | ENST00000503646 | IPO11 | chr5 | 61770291 | + | TNFAIP8 | chr5 | 118728511 | + |
| In-frame | ENST00000409296 | ENST00000504642 | IPO11 | chr5 | 61770291 | + | TNFAIP8 | chr5 | 118728511 | + |
| 5CDS-3UTR | ENST00000409296 | ENST00000415806 | IPO11 | chr5 | 61770291 | + | TNFAIP8 | chr5 | 118728511 | + |
| intron-3CDS | ENST00000409534 | ENST00000274456 | IPO11 | chr5 | 61770291 | + | TNFAIP8 | chr5 | 118728511 | + |
| intron-3CDS | ENST00000409534 | ENST00000513374 | IPO11 | chr5 | 61770291 | + | TNFAIP8 | chr5 | 118728511 | + |
| intron-3CDS | ENST00000409534 | ENST00000504771 | IPO11 | chr5 | 61770291 | + | TNFAIP8 | chr5 | 118728511 | + |
| intron-3CDS | ENST00000409534 | ENST00000503646 | IPO11 | chr5 | 61770291 | + | TNFAIP8 | chr5 | 118728511 | + |
| intron-3CDS | ENST00000409534 | ENST00000504642 | IPO11 | chr5 | 61770291 | + | TNFAIP8 | chr5 | 118728511 | + |
| intron-3UTR | ENST00000409534 | ENST00000415806 | IPO11 | chr5 | 61770291 | + | TNFAIP8 | chr5 | 118728511 | + |
| intron-3CDS | ENST00000512177 | ENST00000274456 | IPO11 | chr5 | 61770291 | + | TNFAIP8 | chr5 | 118728511 | + |
| intron-3CDS | ENST00000512177 | ENST00000513374 | IPO11 | chr5 | 61770291 | + | TNFAIP8 | chr5 | 118728511 | + |
| intron-3CDS | ENST00000512177 | ENST00000504771 | IPO11 | chr5 | 61770291 | + | TNFAIP8 | chr5 | 118728511 | + |
| intron-3CDS | ENST00000512177 | ENST00000503646 | IPO11 | chr5 | 61770291 | + | TNFAIP8 | chr5 | 118728511 | + |
| intron-3CDS | ENST00000512177 | ENST00000504642 | IPO11 | chr5 | 61770291 | + | TNFAIP8 | chr5 | 118728511 | + |
| intron-3UTR | ENST00000512177 | ENST00000415806 | IPO11 | chr5 | 61770291 | + | TNFAIP8 | chr5 | 118728511 | + |
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FusionProtFeatures for IPO11_TNFAIP8 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| IPO11 | TNFAIP8 |
| Functions in nuclear protein import as nuclear transportreceptor. Serves as receptor for nuclear localization signals(NLS) in cargo substrates. Is thought to mediate docking of theimportin/substrate complex to the nuclear pore complex (NPC)through binding to nucleoporin and the complex is subsequentlytranslocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ranbinds to the importin, the importin/substrate complex dissociatesand importin is re-exported from the nucleus to the cytoplasmwhere GTP hydrolysis releases Ran. The directionality of nuclearimport is thought to be conferred by an asymmetric distribution ofthe GTP- and GDP-bound forms of Ran between the cytoplasm andnucleus (By similarity). Mediates the nuclear import of UBE2E3,and of RPL12 (By similarity). {ECO:0000250,ECO:0000269|PubMed:11032817}. | Acts as a negative mediator of apoptosis and may play arole in tumor progression. Suppresses the TNF-mediated apoptosisby inhibiting caspase-8 activity but not the processing ofprocaspase-8, subsequently resulting in inhibition of BID cleavageand caspase-3 activation. {ECO:0000269|PubMed:10644768,ECO:0000269|PubMed:11346652, ECO:0000269|PubMed:14724590}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
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FusionGeneSequence for IPO11_TNFAIP8 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_IPO11_ENST00000325324_chr5_61770291_+_TNFAIP8_ENST00000513374_chr5_118728511_+_441aa MDLNSASTVVLQVLTQATSQDTAVLKPAEEQLKQWETQPGFYSVLLNIFTNHTLDINVRWLAVLYFKHGIDRYWRRVAPHALSEEEKTTL RAGLITNFNEPINQIATQIAVLIAKVARLDCPRQWPELIPTLIESVKVQDDLRQHRALLTFYHVTKTLASKRLAADRKLFYDLASGIYNF ACSLWNHHTDTFLQEVSSGNEAAILSSLERTLLSLKVLRKLTVNGFVEPHKNMEVMGFLHGIFERLKQFLECMATDVFNSKNLAVQAQKK ILGKMVSKSIATTLIDDTSSEVLDELYRVTREYTQNKKEAEKIIKNLIKTVIKLAILYRNNQFNQDELALMEKFKKKVHQLAMTVVSFHQ >In-frame_IPO11_ENST00000325324_chr5_61770291_+_TNFAIP8_ENST00000503646_chr5_118728511_+_441aa MDLNSASTVVLQVLTQATSQDTAVLKPAEEQLKQWETQPGFYSVLLNIFTNHTLDINVRWLAVLYFKHGIDRYWRRVAPHALSEEEKTTL RAGLITNFNEPINQIATQIAVLIAKVARLDCPRQWPELIPTLIESVKVQDDLRQHRALLTFYHVTKTLASKRLAADRKLFYDLASGIYNF ACSLWNHHTDTFLQEVSSGNEAAILSSLERTLLSLKVLRKLTVNGFVEPHKNMEVMGFLHGIFERLKQFLECMATDVFNSKNLAVQAQKK ILGKMVSKSIATTLIDDTSSEVLDELYRVTREYTQNKKEAEKIIKNLIKTVIKLAILYRNNQFNQDELALMEKFKKKVHQLAMTVVSFHQ >In-frame_IPO11_ENST00000325324_chr5_61770291_+_TNFAIP8_ENST00000504642_chr5_118728511_+_441aa MDLNSASTVVLQVLTQATSQDTAVLKPAEEQLKQWETQPGFYSVLLNIFTNHTLDINVRWLAVLYFKHGIDRYWRRVAPHALSEEEKTTL RAGLITNFNEPINQIATQIAVLIAKVARLDCPRQWPELIPTLIESVKVQDDLRQHRALLTFYHVTKTLASKRLAADRKLFYDLASGIYNF ACSLWNHHTDTFLQEVSSGNEAAILSSLERTLLSLKVLRKLTVNGFVEPHKNMEVMGFLHGIFERLKQFLECMATDVFNSKNLAVQAQKK ILGKMVSKSIATTLIDDTSSEVLDELYRVTREYTQNKKEAEKIIKNLIKTVIKLAILYRNNQFNQDELALMEKFKKKVHQLAMTVVSFHQ >In-frame_IPO11_ENST00000409296_chr5_61770291_+_TNFAIP8_ENST00000513374_chr5_118728511_+_481aa MVQPIIHLGYVVYSLLYLGYKPVQHVTALNTVSSCHKMVSMDLNSASTVVLQVLTQATSQDTAVLKPAEEQLKQWETQPGFYSVLLNIFT NHTLDINVRWLAVLYFKHGIDRYWRRVAPHALSEEEKTTLRAGLITNFNEPINQIATQIAVLIAKVARLDCPRQWPELIPTLIESVKVQD DLRQHRALLTFYHVTKTLASKRLAADRKLFYDLASGIYNFACSLWNHHTDTFLQEVSSGNEAAILSSLERTLLSLKVLRKLTVNGFVEPH KNMEVMGFLHGIFERLKQFLECMATDVFNSKNLAVQAQKKILGKMVSKSIATTLIDDTSSEVLDELYRVTREYTQNKKEAEKIIKNLIKT VIKLAILYRNNQFNQDELALMEKFKKKVHQLAMTVVSFHQVDYTFDRNVLSRLLNECREMLHQIIQRHLTAKSHGRVNNVFDHFSDCEFL >In-frame_IPO11_ENST00000409296_chr5_61770291_+_TNFAIP8_ENST00000503646_chr5_118728511_+_481aa MVQPIIHLGYVVYSLLYLGYKPVQHVTALNTVSSCHKMVSMDLNSASTVVLQVLTQATSQDTAVLKPAEEQLKQWETQPGFYSVLLNIFT NHTLDINVRWLAVLYFKHGIDRYWRRVAPHALSEEEKTTLRAGLITNFNEPINQIATQIAVLIAKVARLDCPRQWPELIPTLIESVKVQD DLRQHRALLTFYHVTKTLASKRLAADRKLFYDLASGIYNFACSLWNHHTDTFLQEVSSGNEAAILSSLERTLLSLKVLRKLTVNGFVEPH KNMEVMGFLHGIFERLKQFLECMATDVFNSKNLAVQAQKKILGKMVSKSIATTLIDDTSSEVLDELYRVTREYTQNKKEAEKIIKNLIKT VIKLAILYRNNQFNQDELALMEKFKKKVHQLAMTVVSFHQVDYTFDRNVLSRLLNECREMLHQIIQRHLTAKSHGRVNNVFDHFSDCEFL >In-frame_IPO11_ENST00000409296_chr5_61770291_+_TNFAIP8_ENST00000504642_chr5_118728511_+_481aa MVQPIIHLGYVVYSLLYLGYKPVQHVTALNTVSSCHKMVSMDLNSASTVVLQVLTQATSQDTAVLKPAEEQLKQWETQPGFYSVLLNIFT NHTLDINVRWLAVLYFKHGIDRYWRRVAPHALSEEEKTTLRAGLITNFNEPINQIATQIAVLIAKVARLDCPRQWPELIPTLIESVKVQD DLRQHRALLTFYHVTKTLASKRLAADRKLFYDLASGIYNFACSLWNHHTDTFLQEVSSGNEAAILSSLERTLLSLKVLRKLTVNGFVEPH KNMEVMGFLHGIFERLKQFLECMATDVFNSKNLAVQAQKKILGKMVSKSIATTLIDDTSSEVLDELYRVTREYTQNKKEAEKIIKNLIKT VIKLAILYRNNQFNQDELALMEKFKKKVHQLAMTVVSFHQVDYTFDRNVLSRLLNECREMLHQIIQRHLTAKSHGRVNNVFDHFSDCEFL |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_IPO11_ENST00000325324_chr5_61770291_+_TNFAIP8_ENST00000513374_chr5_118728511_+_1323nt ATGGATCTCAATAGTGCCAGCACTGTTGTTCTTCAGGTGTTAACACAGGCCACCAGTCAGGATACTGCTGTGTTAAAACCAGCTGAGGAG CAGTTGAAGCAGTGGGAGACACAGCCAGGTTTCTATTCAGTGTTGCTGAATATTTTCACCAACCACACTTTGGATATAAATGTAAGGTGG CTTGCTGTACTGTATTTTAAACATGGAATTGATCGCTACTGGAGACGTGTAGCACCTCATGCTCTCTCAGAGGAGGAGAAAACTACTCTG CGTGCAGGGCTCATCACCAACTTCAATGAACCAATAAACCAGATTGCAACTCAGATTGCAGTGCTCATTGCAAAAGTTGCTAGATTGGAT TGTCCCAGACAGTGGCCTGAACTAATTCCCACTCTTATAGAGTCTGTTAAAGTCCAGGATGATCTTCGACAGCACAGAGCATTACTTACC TTCTATCATGTTACCAAGACACTGGCATCTAAACGACTTGCTGCTGATAGAAAACTATTTTATGATTTAGCTTCTGGAATTTATAATTTT GCCTGCTCTCTGTGGAATCACCACACAGACACATTCCTGCAAGAAGTTTCTTCTGGCAATGAAGCTGCAATTTTGAGTTCACTAGAACGA ACACTGCTATCATTGAAAGTGCTGCGTAAGTTAACTGTTAATGGATTTGTGGAACCTCATAAGAATATGGAGGTGATGGGTTTTTTACAT GGAATATTTGAACGTCTAAAACAGTTTCTGGAATGCATGGCCACAGATGTCTTTAATTCCAAAAACCTGGCCGTTCAGGCACAAAAGAAG ATCTTGGGTAAAATGGTGTCCAAATCCATCGCCACCACCTTAATAGACGACACAAGTAGTGAGGTGCTGGATGAGCTCTACAGAGTGACC AGGGAGTACACCCAAAACAAGAAGGAGGCAGAGAAGATCATCAAGAACCTCATCAAGACAGTCATCAAGCTGGCCATTCTTTATAGGAAT AATCAGTTTAATCAAGATGAGCTAGCATTGATGGAGAAATTTAAGAAGAAAGTTCATCAGCTTGCTATGACCGTGGTCAGTTTCCATCAG GTGGATTATACCTTTGACCGGAATGTGTTATCCAGGCTGTTAAATGAATGCAGAGAGATGCTGCACCAAATCATTCAGCGCCACCTCACT GCCAAGTCACATGGACGGGTTAATAATGTGTTTGATCATTTTTCAGATTGTGAATTTTTGGCTGCCTTGTATAATCCTTTTGGGAATTTT >In-frame_IPO11_ENST00000325324_chr5_61770291_+_TNFAIP8_ENST00000503646_chr5_118728511_+_1323nt ATGGATCTCAATAGTGCCAGCACTGTTGTTCTTCAGGTGTTAACACAGGCCACCAGTCAGGATACTGCTGTGTTAAAACCAGCTGAGGAG CAGTTGAAGCAGTGGGAGACACAGCCAGGTTTCTATTCAGTGTTGCTGAATATTTTCACCAACCACACTTTGGATATAAATGTAAGGTGG CTTGCTGTACTGTATTTTAAACATGGAATTGATCGCTACTGGAGACGTGTAGCACCTCATGCTCTCTCAGAGGAGGAGAAAACTACTCTG CGTGCAGGGCTCATCACCAACTTCAATGAACCAATAAACCAGATTGCAACTCAGATTGCAGTGCTCATTGCAAAAGTTGCTAGATTGGAT TGTCCCAGACAGTGGCCTGAACTAATTCCCACTCTTATAGAGTCTGTTAAAGTCCAGGATGATCTTCGACAGCACAGAGCATTACTTACC TTCTATCATGTTACCAAGACACTGGCATCTAAACGACTTGCTGCTGATAGAAAACTATTTTATGATTTAGCTTCTGGAATTTATAATTTT GCCTGCTCTCTGTGGAATCACCACACAGACACATTCCTGCAAGAAGTTTCTTCTGGCAATGAAGCTGCAATTTTGAGTTCACTAGAACGA ACACTGCTATCATTGAAAGTGCTGCGTAAGTTAACTGTTAATGGATTTGTGGAACCTCATAAGAATATGGAGGTGATGGGTTTTTTACAT GGAATATTTGAACGTCTAAAACAGTTTCTGGAATGCATGGCCACAGATGTCTTTAATTCCAAAAACCTGGCCGTTCAGGCACAAAAGAAG ATCTTGGGTAAAATGGTGTCCAAATCCATCGCCACCACCTTAATAGACGACACAAGTAGTGAGGTGCTGGATGAGCTCTACAGAGTGACC AGGGAGTACACCCAAAACAAGAAGGAGGCAGAGAAGATCATCAAGAACCTCATCAAGACAGTCATCAAGCTGGCCATTCTTTATAGGAAT AATCAGTTTAATCAAGATGAGCTAGCATTGATGGAGAAATTTAAGAAGAAAGTTCATCAGCTTGCTATGACCGTGGTCAGTTTCCATCAG GTGGATTATACCTTTGACCGGAATGTGTTATCCAGGCTGTTAAATGAATGCAGAGAGATGCTGCACCAAATCATTCAGCGCCACCTCACT GCCAAGTCACATGGACGGGTTAATAATGTGTTTGATCATTTTTCAGATTGTGAATTTTTGGCTGCCTTGTATAATCCTTTTGGGAATTTT >In-frame_IPO11_ENST00000325324_chr5_61770291_+_TNFAIP8_ENST00000504642_chr5_118728511_+_1323nt ATGGATCTCAATAGTGCCAGCACTGTTGTTCTTCAGGTGTTAACACAGGCCACCAGTCAGGATACTGCTGTGTTAAAACCAGCTGAGGAG CAGTTGAAGCAGTGGGAGACACAGCCAGGTTTCTATTCAGTGTTGCTGAATATTTTCACCAACCACACTTTGGATATAAATGTAAGGTGG CTTGCTGTACTGTATTTTAAACATGGAATTGATCGCTACTGGAGACGTGTAGCACCTCATGCTCTCTCAGAGGAGGAGAAAACTACTCTG CGTGCAGGGCTCATCACCAACTTCAATGAACCAATAAACCAGATTGCAACTCAGATTGCAGTGCTCATTGCAAAAGTTGCTAGATTGGAT TGTCCCAGACAGTGGCCTGAACTAATTCCCACTCTTATAGAGTCTGTTAAAGTCCAGGATGATCTTCGACAGCACAGAGCATTACTTACC TTCTATCATGTTACCAAGACACTGGCATCTAAACGACTTGCTGCTGATAGAAAACTATTTTATGATTTAGCTTCTGGAATTTATAATTTT GCCTGCTCTCTGTGGAATCACCACACAGACACATTCCTGCAAGAAGTTTCTTCTGGCAATGAAGCTGCAATTTTGAGTTCACTAGAACGA ACACTGCTATCATTGAAAGTGCTGCGTAAGTTAACTGTTAATGGATTTGTGGAACCTCATAAGAATATGGAGGTGATGGGTTTTTTACAT GGAATATTTGAACGTCTAAAACAGTTTCTGGAATGCATGGCCACAGATGTCTTTAATTCCAAAAACCTGGCCGTTCAGGCACAAAAGAAG ATCTTGGGTAAAATGGTGTCCAAATCCATCGCCACCACCTTAATAGACGACACAAGTAGTGAGGTGCTGGATGAGCTCTACAGAGTGACC AGGGAGTACACCCAAAACAAGAAGGAGGCAGAGAAGATCATCAAGAACCTCATCAAGACAGTCATCAAGCTGGCCATTCTTTATAGGAAT AATCAGTTTAATCAAGATGAGCTAGCATTGATGGAGAAATTTAAGAAGAAAGTTCATCAGCTTGCTATGACCGTGGTCAGTTTCCATCAG GTGGATTATACCTTTGACCGGAATGTGTTATCCAGGCTGTTAAATGAATGCAGAGAGATGCTGCACCAAATCATTCAGCGCCACCTCACT GCCAAGTCACATGGACGGGTTAATAATGTGTTTGATCATTTTTCAGATTGTGAATTTTTGGCTGCCTTGTATAATCCTTTTGGGAATTTT >In-frame_IPO11_ENST00000409296_chr5_61770291_+_TNFAIP8_ENST00000513374_chr5_118728511_+_1443nt ATGGTACAGCCTATTATACACTTGGGCTATGTGGTATATAGCTTATTGTATCTAGGCTATAAGCCTGTACAGCATGTTACTGCACTGAAT ACTGTAAGCAGTTGTCACAAAATGGTTTCCATGGATCTCAATAGTGCCAGCACTGTTGTTCTTCAGGTGTTAACACAGGCCACCAGTCAG GATACTGCTGTGTTAAAACCAGCTGAGGAGCAGTTGAAGCAGTGGGAGACACAGCCAGGTTTCTATTCAGTGTTGCTGAATATTTTCACC AACCACACTTTGGATATAAATGTAAGGTGGCTTGCTGTACTGTATTTTAAACATGGAATTGATCGCTACTGGAGACGTGTAGCACCTCAT GCTCTCTCAGAGGAGGAGAAAACTACTCTGCGTGCAGGGCTCATCACCAACTTCAATGAACCAATAAACCAGATTGCAACTCAGATTGCA GTGCTCATTGCAAAAGTTGCTAGATTGGATTGTCCCAGACAGTGGCCTGAACTAATTCCCACTCTTATAGAGTCTGTTAAAGTCCAGGAT GATCTTCGACAGCACAGAGCATTACTTACCTTCTATCATGTTACCAAGACACTGGCATCTAAACGACTTGCTGCTGATAGAAAACTATTT TATGATTTAGCTTCTGGAATTTATAATTTTGCCTGCTCTCTGTGGAATCACCACACAGACACATTCCTGCAAGAAGTTTCTTCTGGCAAT GAAGCTGCAATTTTGAGTTCACTAGAACGAACACTGCTATCATTGAAAGTGCTGCGTAAGTTAACTGTTAATGGATTTGTGGAACCTCAT AAGAATATGGAGGTGATGGGTTTTTTACATGGAATATTTGAACGTCTAAAACAGTTTCTGGAATGCATGGCCACAGATGTCTTTAATTCC AAAAACCTGGCCGTTCAGGCACAAAAGAAGATCTTGGGTAAAATGGTGTCCAAATCCATCGCCACCACCTTAATAGACGACACAAGTAGT GAGGTGCTGGATGAGCTCTACAGAGTGACCAGGGAGTACACCCAAAACAAGAAGGAGGCAGAGAAGATCATCAAGAACCTCATCAAGACA GTCATCAAGCTGGCCATTCTTTATAGGAATAATCAGTTTAATCAAGATGAGCTAGCATTGATGGAGAAATTTAAGAAGAAAGTTCATCAG CTTGCTATGACCGTGGTCAGTTTCCATCAGGTGGATTATACCTTTGACCGGAATGTGTTATCCAGGCTGTTAAATGAATGCAGAGAGATG CTGCACCAAATCATTCAGCGCCACCTCACTGCCAAGTCACATGGACGGGTTAATAATGTGTTTGATCATTTTTCAGATTGTGAATTTTTG GCTGCCTTGTATAATCCTTTTGGGAATTTTAAACCCCACTTACAAAAACTATGTGATGGTATCAACAAAATGTTGGATGAAGAGAACATA >In-frame_IPO11_ENST00000409296_chr5_61770291_+_TNFAIP8_ENST00000503646_chr5_118728511_+_1443nt ATGGTACAGCCTATTATACACTTGGGCTATGTGGTATATAGCTTATTGTATCTAGGCTATAAGCCTGTACAGCATGTTACTGCACTGAAT ACTGTAAGCAGTTGTCACAAAATGGTTTCCATGGATCTCAATAGTGCCAGCACTGTTGTTCTTCAGGTGTTAACACAGGCCACCAGTCAG GATACTGCTGTGTTAAAACCAGCTGAGGAGCAGTTGAAGCAGTGGGAGACACAGCCAGGTTTCTATTCAGTGTTGCTGAATATTTTCACC AACCACACTTTGGATATAAATGTAAGGTGGCTTGCTGTACTGTATTTTAAACATGGAATTGATCGCTACTGGAGACGTGTAGCACCTCAT GCTCTCTCAGAGGAGGAGAAAACTACTCTGCGTGCAGGGCTCATCACCAACTTCAATGAACCAATAAACCAGATTGCAACTCAGATTGCA GTGCTCATTGCAAAAGTTGCTAGATTGGATTGTCCCAGACAGTGGCCTGAACTAATTCCCACTCTTATAGAGTCTGTTAAAGTCCAGGAT GATCTTCGACAGCACAGAGCATTACTTACCTTCTATCATGTTACCAAGACACTGGCATCTAAACGACTTGCTGCTGATAGAAAACTATTT TATGATTTAGCTTCTGGAATTTATAATTTTGCCTGCTCTCTGTGGAATCACCACACAGACACATTCCTGCAAGAAGTTTCTTCTGGCAAT GAAGCTGCAATTTTGAGTTCACTAGAACGAACACTGCTATCATTGAAAGTGCTGCGTAAGTTAACTGTTAATGGATTTGTGGAACCTCAT AAGAATATGGAGGTGATGGGTTTTTTACATGGAATATTTGAACGTCTAAAACAGTTTCTGGAATGCATGGCCACAGATGTCTTTAATTCC AAAAACCTGGCCGTTCAGGCACAAAAGAAGATCTTGGGTAAAATGGTGTCCAAATCCATCGCCACCACCTTAATAGACGACACAAGTAGT GAGGTGCTGGATGAGCTCTACAGAGTGACCAGGGAGTACACCCAAAACAAGAAGGAGGCAGAGAAGATCATCAAGAACCTCATCAAGACA GTCATCAAGCTGGCCATTCTTTATAGGAATAATCAGTTTAATCAAGATGAGCTAGCATTGATGGAGAAATTTAAGAAGAAAGTTCATCAG CTTGCTATGACCGTGGTCAGTTTCCATCAGGTGGATTATACCTTTGACCGGAATGTGTTATCCAGGCTGTTAAATGAATGCAGAGAGATG CTGCACCAAATCATTCAGCGCCACCTCACTGCCAAGTCACATGGACGGGTTAATAATGTGTTTGATCATTTTTCAGATTGTGAATTTTTG GCTGCCTTGTATAATCCTTTTGGGAATTTTAAACCCCACTTACAAAAACTATGTGATGGTATCAACAAAATGTTGGATGAAGAGAACATA >In-frame_IPO11_ENST00000409296_chr5_61770291_+_TNFAIP8_ENST00000504642_chr5_118728511_+_1443nt ATGGTACAGCCTATTATACACTTGGGCTATGTGGTATATAGCTTATTGTATCTAGGCTATAAGCCTGTACAGCATGTTACTGCACTGAAT ACTGTAAGCAGTTGTCACAAAATGGTTTCCATGGATCTCAATAGTGCCAGCACTGTTGTTCTTCAGGTGTTAACACAGGCCACCAGTCAG GATACTGCTGTGTTAAAACCAGCTGAGGAGCAGTTGAAGCAGTGGGAGACACAGCCAGGTTTCTATTCAGTGTTGCTGAATATTTTCACC AACCACACTTTGGATATAAATGTAAGGTGGCTTGCTGTACTGTATTTTAAACATGGAATTGATCGCTACTGGAGACGTGTAGCACCTCAT GCTCTCTCAGAGGAGGAGAAAACTACTCTGCGTGCAGGGCTCATCACCAACTTCAATGAACCAATAAACCAGATTGCAACTCAGATTGCA GTGCTCATTGCAAAAGTTGCTAGATTGGATTGTCCCAGACAGTGGCCTGAACTAATTCCCACTCTTATAGAGTCTGTTAAAGTCCAGGAT GATCTTCGACAGCACAGAGCATTACTTACCTTCTATCATGTTACCAAGACACTGGCATCTAAACGACTTGCTGCTGATAGAAAACTATTT TATGATTTAGCTTCTGGAATTTATAATTTTGCCTGCTCTCTGTGGAATCACCACACAGACACATTCCTGCAAGAAGTTTCTTCTGGCAAT GAAGCTGCAATTTTGAGTTCACTAGAACGAACACTGCTATCATTGAAAGTGCTGCGTAAGTTAACTGTTAATGGATTTGTGGAACCTCAT AAGAATATGGAGGTGATGGGTTTTTTACATGGAATATTTGAACGTCTAAAACAGTTTCTGGAATGCATGGCCACAGATGTCTTTAATTCC AAAAACCTGGCCGTTCAGGCACAAAAGAAGATCTTGGGTAAAATGGTGTCCAAATCCATCGCCACCACCTTAATAGACGACACAAGTAGT GAGGTGCTGGATGAGCTCTACAGAGTGACCAGGGAGTACACCCAAAACAAGAAGGAGGCAGAGAAGATCATCAAGAACCTCATCAAGACA GTCATCAAGCTGGCCATTCTTTATAGGAATAATCAGTTTAATCAAGATGAGCTAGCATTGATGGAGAAATTTAAGAAGAAAGTTCATCAG CTTGCTATGACCGTGGTCAGTTTCCATCAGGTGGATTATACCTTTGACCGGAATGTGTTATCCAGGCTGTTAAATGAATGCAGAGAGATG CTGCACCAAATCATTCAGCGCCACCTCACTGCCAAGTCACATGGACGGGTTAATAATGTGTTTGATCATTTTTCAGATTGTGAATTTTTG GCTGCCTTGTATAATCCTTTTGGGAATTTTAAACCCCACTTACAAAAACTATGTGATGGTATCAACAAAATGTTGGATGAAGAGAACATA |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_IPO11_ENST00000325324_chr5_61770291_+_TNFAIP8_ENST00000513374_chr5_118728511_+_1854nt TTTGGAGCTGCGACGCCAAACATGGCGTGTTCCTAGAAGCCGCTTTCGGCATCAGTAGGCGGCGGCGTGGGGTCTGGCAGCGTGGGGAGA GGGACCAACCGACGCCACTTCGTGTTGGGAAGTGGGAGCGGGAGGGCCGGGCAATTCCCGACCGAACCAAACGGTTTCCATGGATCTCAA TAGTGCCAGCACTGTTGTTCTTCAGGTGTTAACACAGGCCACCAGTCAGGATACTGCTGTGTTAAAACCAGCTGAGGAGCAGTTGAAGCA GTGGGAGACACAGCCAGGTTTCTATTCAGTGTTGCTGAATATTTTCACCAACCACACTTTGGATATAAATGTAAGGTGGCTTGCTGTACT GTATTTTAAACATGGAATTGATCGCTACTGGAGACGTGTAGCACCTCATGCTCTCTCAGAGGAGGAGAAAACTACTCTGCGTGCAGGGCT CATCACCAACTTCAATGAACCAATAAACCAGATTGCAACTCAGATTGCAGTGCTCATTGCAAAAGTTGCTAGATTGGATTGTCCCAGACA GTGGCCTGAACTAATTCCCACTCTTATAGAGTCTGTTAAAGTCCAGGATGATCTTCGACAGCACAGAGCATTACTTACCTTCTATCATGT TACCAAGACACTGGCATCTAAACGACTTGCTGCTGATAGAAAACTATTTTATGATTTAGCTTCTGGAATTTATAATTTTGCCTGCTCTCT GTGGAATCACCACACAGACACATTCCTGCAAGAAGTTTCTTCTGGCAATGAAGCTGCAATTTTGAGTTCACTAGAACGAACACTGCTATC ATTGAAAGTGCTGCGTAAGTTAACTGTTAATGGATTTGTGGAACCTCATAAGAATATGGAGGTGATGGGTTTTTTACATGGAATATTTGA ACGTCTAAAACAGTTTCTGGAATGCATGGCCACAGATGTCTTTAATTCCAAAAACCTGGCCGTTCAGGCACAAAAGAAGATCTTGGGTAA AATGGTGTCCAAATCCATCGCCACCACCTTAATAGACGACACAAGTAGTGAGGTGCTGGATGAGCTCTACAGAGTGACCAGGGAGTACAC CCAAAACAAGAAGGAGGCAGAGAAGATCATCAAGAACCTCATCAAGACAGTCATCAAGCTGGCCATTCTTTATAGGAATAATCAGTTTAA TCAAGATGAGCTAGCATTGATGGAGAAATTTAAGAAGAAAGTTCATCAGCTTGCTATGACCGTGGTCAGTTTCCATCAGGTGGATTATAC CTTTGACCGGAATGTGTTATCCAGGCTGTTAAATGAATGCAGAGAGATGCTGCACCAAATCATTCAGCGCCACCTCACTGCCAAGTCACA TGGACGGGTTAATAATGTGTTTGATCATTTTTCAGATTGTGAATTTTTGGCTGCCTTGTATAATCCTTTTGGGAATTTTAAACCCCACTT ACAAAAACTATGTGATGGTATCAACAAAATGTTGGATGAAGAGAACATATGAGCACATGAGTTAAGATTGTGACTGATCATGATTTATTT GAAGATGGAGCACTGCTGATTTATGAAGGAAAAAAGAAGAATTTTCTAAAGATTACACATATTTCAGAAAGACTTTACCCAATTCAGTTG TCAGACATAATGATTTATTTGAAGGCTTGTTTTATTTGAAGAAAAGCATATTGCCAAAAATTCTGGTTAAAAGCTTCCTAACGGGTAACA GACCATGGGAGAGATATGTGGTTGGGTAATGCAAATGTAGTTATACAAAGAAAAATACAGATGTCTCCAGACCTGAGGACTTTTTAATAG >In-frame_IPO11_ENST00000325324_chr5_61770291_+_TNFAIP8_ENST00000503646_chr5_118728511_+_2709nt TTTGGAGCTGCGACGCCAAACATGGCGTGTTCCTAGAAGCCGCTTTCGGCATCAGTAGGCGGCGGCGTGGGGTCTGGCAGCGTGGGGAGA GGGACCAACCGACGCCACTTCGTGTTGGGAAGTGGGAGCGGGAGGGCCGGGCAATTCCCGACCGAACCAAACGGTTTCCATGGATCTCAA TAGTGCCAGCACTGTTGTTCTTCAGGTGTTAACACAGGCCACCAGTCAGGATACTGCTGTGTTAAAACCAGCTGAGGAGCAGTTGAAGCA GTGGGAGACACAGCCAGGTTTCTATTCAGTGTTGCTGAATATTTTCACCAACCACACTTTGGATATAAATGTAAGGTGGCTTGCTGTACT GTATTTTAAACATGGAATTGATCGCTACTGGAGACGTGTAGCACCTCATGCTCTCTCAGAGGAGGAGAAAACTACTCTGCGTGCAGGGCT CATCACCAACTTCAATGAACCAATAAACCAGATTGCAACTCAGATTGCAGTGCTCATTGCAAAAGTTGCTAGATTGGATTGTCCCAGACA GTGGCCTGAACTAATTCCCACTCTTATAGAGTCTGTTAAAGTCCAGGATGATCTTCGACAGCACAGAGCATTACTTACCTTCTATCATGT TACCAAGACACTGGCATCTAAACGACTTGCTGCTGATAGAAAACTATTTTATGATTTAGCTTCTGGAATTTATAATTTTGCCTGCTCTCT GTGGAATCACCACACAGACACATTCCTGCAAGAAGTTTCTTCTGGCAATGAAGCTGCAATTTTGAGTTCACTAGAACGAACACTGCTATC ATTGAAAGTGCTGCGTAAGTTAACTGTTAATGGATTTGTGGAACCTCATAAGAATATGGAGGTGATGGGTTTTTTACATGGAATATTTGA ACGTCTAAAACAGTTTCTGGAATGCATGGCCACAGATGTCTTTAATTCCAAAAACCTGGCCGTTCAGGCACAAAAGAAGATCTTGGGTAA AATGGTGTCCAAATCCATCGCCACCACCTTAATAGACGACACAAGTAGTGAGGTGCTGGATGAGCTCTACAGAGTGACCAGGGAGTACAC CCAAAACAAGAAGGAGGCAGAGAAGATCATCAAGAACCTCATCAAGACAGTCATCAAGCTGGCCATTCTTTATAGGAATAATCAGTTTAA TCAAGATGAGCTAGCATTGATGGAGAAATTTAAGAAGAAAGTTCATCAGCTTGCTATGACCGTGGTCAGTTTCCATCAGGTGGATTATAC CTTTGACCGGAATGTGTTATCCAGGCTGTTAAATGAATGCAGAGAGATGCTGCACCAAATCATTCAGCGCCACCTCACTGCCAAGTCACA TGGACGGGTTAATAATGTGTTTGATCATTTTTCAGATTGTGAATTTTTGGCTGCCTTGTATAATCCTTTTGGGAATTTTAAACCCCACTT ACAAAAACTATGTGATGGTATCAACAAAATGTTGGATGAAGAGAACATATGAGCACATGAGTTAAGATTGTGACTGATCATGATTTATTT GAAGATGGAGCACTGCTGATTTATGAAGGAAAAAAGAAGAATTTTCTAAAGATTACACATATTTCAGAAAGACTTTACCCAATTCAGTTG TCAGACATAATGATTTATTTGAAGGCTTGTTTTATTTGAAGAAAAGCATATTGCCAAAAATTCTGGTTAAAAGCTTCCTAACGGGTAACA GACCATGGGAGAGATATGTGGTTGGGTAATGCAAATGTAGTTATACAAAGAAAAATACAGATGTCTCCAGACCTGAGGACTTTTTAATAG GGCAGTTGTTGTGTTGGTGGCACATTGGATATTTCTAACATGTACAAAGCTATGTATTTTGATTTACTTTCATTTCTTGCTATGTATATG TACTTTTCTTAAAATGCCAAGAACTTTCTCTTGCTATCATTGCTCCTTTTGAAACAATTCAATTTTCATGTCTACAGCTGACTGTTTTGT TAAGATTGAGTCATCGACATTCAGGATTTAAGTCTGAGGTAGTCAACCCTCAGGAAAAAAAAAATGGCTTATCTGAAATCAGTACTGTGG AAATGAACTATATTAGCTATTATGAATAATGTCCAGTATAAGAATATGCTTCTGGAATTGAGTTCTCCTTTTAAGTACCAATGATACTTA AATTTCTCAGAAATGTAATGGTGTGTCATTGCCTTGAAATGCTTGCTTAGGGCTTCTTTTATGTTATCTTAAAAAGTGCTGGTGAATTTT CCATTTTTTACATCCATTTCACATGTAAGAGACAAAAAAGTCTAGATTGGTCTTGATATTGAGATAATAAAAAGTAAGTAGCATTAAGAA AGGTAACAATCTTCATTCTACAGATGAACTCATTGAAACAATTTAGGGGAATGAGGGGCAAAAGGGGAGAAATACTGCTAAAGAACATGA GCATAAAAATGCGTGCGTTTCAGTGTTTAAGAAGGCTTGATAAAGAATGTCACTTTTTTATTTAACTGATAAGATTTTTGTTATTTTTTA CTTTGATAAGTAAACCAAAGAATATTTGTATTTCAAGCAGTTTGTGTGGTGTTTCTATATAATTTTCTGTGTATAAATAATAAAGTAGGC ATTTGTTTATTTTGTAAAAAAGAAATGAAAATCTGCTGGCCAGCTATGTCCTCTAGGAAATGACAGACCCAACCACCAGCAATAAACATT >In-frame_IPO11_ENST00000325324_chr5_61770291_+_TNFAIP8_ENST00000504642_chr5_118728511_+_1557nt TTTGGAGCTGCGACGCCAAACATGGCGTGTTCCTAGAAGCCGCTTTCGGCATCAGTAGGCGGCGGCGTGGGGTCTGGCAGCGTGGGGAGA GGGACCAACCGACGCCACTTCGTGTTGGGAAGTGGGAGCGGGAGGGCCGGGCAATTCCCGACCGAACCAAACGGTTTCCATGGATCTCAA TAGTGCCAGCACTGTTGTTCTTCAGGTGTTAACACAGGCCACCAGTCAGGATACTGCTGTGTTAAAACCAGCTGAGGAGCAGTTGAAGCA GTGGGAGACACAGCCAGGTTTCTATTCAGTGTTGCTGAATATTTTCACCAACCACACTTTGGATATAAATGTAAGGTGGCTTGCTGTACT GTATTTTAAACATGGAATTGATCGCTACTGGAGACGTGTAGCACCTCATGCTCTCTCAGAGGAGGAGAAAACTACTCTGCGTGCAGGGCT CATCACCAACTTCAATGAACCAATAAACCAGATTGCAACTCAGATTGCAGTGCTCATTGCAAAAGTTGCTAGATTGGATTGTCCCAGACA GTGGCCTGAACTAATTCCCACTCTTATAGAGTCTGTTAAAGTCCAGGATGATCTTCGACAGCACAGAGCATTACTTACCTTCTATCATGT TACCAAGACACTGGCATCTAAACGACTTGCTGCTGATAGAAAACTATTTTATGATTTAGCTTCTGGAATTTATAATTTTGCCTGCTCTCT GTGGAATCACCACACAGACACATTCCTGCAAGAAGTTTCTTCTGGCAATGAAGCTGCAATTTTGAGTTCACTAGAACGAACACTGCTATC ATTGAAAGTGCTGCGTAAGTTAACTGTTAATGGATTTGTGGAACCTCATAAGAATATGGAGGTGATGGGTTTTTTACATGGAATATTTGA ACGTCTAAAACAGTTTCTGGAATGCATGGCCACAGATGTCTTTAATTCCAAAAACCTGGCCGTTCAGGCACAAAAGAAGATCTTGGGTAA AATGGTGTCCAAATCCATCGCCACCACCTTAATAGACGACACAAGTAGTGAGGTGCTGGATGAGCTCTACAGAGTGACCAGGGAGTACAC CCAAAACAAGAAGGAGGCAGAGAAGATCATCAAGAACCTCATCAAGACAGTCATCAAGCTGGCCATTCTTTATAGGAATAATCAGTTTAA TCAAGATGAGCTAGCATTGATGGAGAAATTTAAGAAGAAAGTTCATCAGCTTGCTATGACCGTGGTCAGTTTCCATCAGGTGGATTATAC CTTTGACCGGAATGTGTTATCCAGGCTGTTAAATGAATGCAGAGAGATGCTGCACCAAATCATTCAGCGCCACCTCACTGCCAAGTCACA TGGACGGGTTAATAATGTGTTTGATCATTTTTCAGATTGTGAATTTTTGGCTGCCTTGTATAATCCTTTTGGGAATTTTAAACCCCACTT ACAAAAACTATGTGATGGTATCAACAAAATGTTGGATGAAGAGAACATATGAGCACATGAGTTAAGATTGTGACTGATCATGATTTATTT >In-frame_IPO11_ENST00000409296_chr5_61770291_+_TNFAIP8_ENST00000513374_chr5_118728511_+_1935nt ATAGCACCAGGTGTGAAACTGCTGGGTCATAGAAGATACAGTCACGAGTTGCTTAAGGCTGGGATACATCCTGAGAAATGGGTCGTTAGG CAATTTTGTTGTTCTATGAACATCATATGAACAAACCTAGATGGTACAGCCTATTATACACTTGGGCTATGTGGTATATAGCTTATTGTA TCTAGGCTATAAGCCTGTACAGCATGTTACTGCACTGAATACTGTAAGCAGTTGTCACAAAATGGTTTCCATGGATCTCAATAGTGCCAG CACTGTTGTTCTTCAGGTGTTAACACAGGCCACCAGTCAGGATACTGCTGTGTTAAAACCAGCTGAGGAGCAGTTGAAGCAGTGGGAGAC ACAGCCAGGTTTCTATTCAGTGTTGCTGAATATTTTCACCAACCACACTTTGGATATAAATGTAAGGTGGCTTGCTGTACTGTATTTTAA ACATGGAATTGATCGCTACTGGAGACGTGTAGCACCTCATGCTCTCTCAGAGGAGGAGAAAACTACTCTGCGTGCAGGGCTCATCACCAA CTTCAATGAACCAATAAACCAGATTGCAACTCAGATTGCAGTGCTCATTGCAAAAGTTGCTAGATTGGATTGTCCCAGACAGTGGCCTGA ACTAATTCCCACTCTTATAGAGTCTGTTAAAGTCCAGGATGATCTTCGACAGCACAGAGCATTACTTACCTTCTATCATGTTACCAAGAC ACTGGCATCTAAACGACTTGCTGCTGATAGAAAACTATTTTATGATTTAGCTTCTGGAATTTATAATTTTGCCTGCTCTCTGTGGAATCA CCACACAGACACATTCCTGCAAGAAGTTTCTTCTGGCAATGAAGCTGCAATTTTGAGTTCACTAGAACGAACACTGCTATCATTGAAAGT GCTGCGTAAGTTAACTGTTAATGGATTTGTGGAACCTCATAAGAATATGGAGGTGATGGGTTTTTTACATGGAATATTTGAACGTCTAAA ACAGTTTCTGGAATGCATGGCCACAGATGTCTTTAATTCCAAAAACCTGGCCGTTCAGGCACAAAAGAAGATCTTGGGTAAAATGGTGTC CAAATCCATCGCCACCACCTTAATAGACGACACAAGTAGTGAGGTGCTGGATGAGCTCTACAGAGTGACCAGGGAGTACACCCAAAACAA GAAGGAGGCAGAGAAGATCATCAAGAACCTCATCAAGACAGTCATCAAGCTGGCCATTCTTTATAGGAATAATCAGTTTAATCAAGATGA GCTAGCATTGATGGAGAAATTTAAGAAGAAAGTTCATCAGCTTGCTATGACCGTGGTCAGTTTCCATCAGGTGGATTATACCTTTGACCG GAATGTGTTATCCAGGCTGTTAAATGAATGCAGAGAGATGCTGCACCAAATCATTCAGCGCCACCTCACTGCCAAGTCACATGGACGGGT TAATAATGTGTTTGATCATTTTTCAGATTGTGAATTTTTGGCTGCCTTGTATAATCCTTTTGGGAATTTTAAACCCCACTTACAAAAACT ATGTGATGGTATCAACAAAATGTTGGATGAAGAGAACATATGAGCACATGAGTTAAGATTGTGACTGATCATGATTTATTTGAAGATGGA GCACTGCTGATTTATGAAGGAAAAAAGAAGAATTTTCTAAAGATTACACATATTTCAGAAAGACTTTACCCAATTCAGTTGTCAGACATA ATGATTTATTTGAAGGCTTGTTTTATTTGAAGAAAAGCATATTGCCAAAAATTCTGGTTAAAAGCTTCCTAACGGGTAACAGACCATGGG AGAGATATGTGGTTGGGTAATGCAAATGTAGTTATACAAAGAAAAATACAGATGTCTCCAGACCTGAGGACTTTTTAATAGGGCAGTTGT >In-frame_IPO11_ENST00000409296_chr5_61770291_+_TNFAIP8_ENST00000503646_chr5_118728511_+_2790nt ATAGCACCAGGTGTGAAACTGCTGGGTCATAGAAGATACAGTCACGAGTTGCTTAAGGCTGGGATACATCCTGAGAAATGGGTCGTTAGG CAATTTTGTTGTTCTATGAACATCATATGAACAAACCTAGATGGTACAGCCTATTATACACTTGGGCTATGTGGTATATAGCTTATTGTA TCTAGGCTATAAGCCTGTACAGCATGTTACTGCACTGAATACTGTAAGCAGTTGTCACAAAATGGTTTCCATGGATCTCAATAGTGCCAG CACTGTTGTTCTTCAGGTGTTAACACAGGCCACCAGTCAGGATACTGCTGTGTTAAAACCAGCTGAGGAGCAGTTGAAGCAGTGGGAGAC ACAGCCAGGTTTCTATTCAGTGTTGCTGAATATTTTCACCAACCACACTTTGGATATAAATGTAAGGTGGCTTGCTGTACTGTATTTTAA ACATGGAATTGATCGCTACTGGAGACGTGTAGCACCTCATGCTCTCTCAGAGGAGGAGAAAACTACTCTGCGTGCAGGGCTCATCACCAA CTTCAATGAACCAATAAACCAGATTGCAACTCAGATTGCAGTGCTCATTGCAAAAGTTGCTAGATTGGATTGTCCCAGACAGTGGCCTGA ACTAATTCCCACTCTTATAGAGTCTGTTAAAGTCCAGGATGATCTTCGACAGCACAGAGCATTACTTACCTTCTATCATGTTACCAAGAC ACTGGCATCTAAACGACTTGCTGCTGATAGAAAACTATTTTATGATTTAGCTTCTGGAATTTATAATTTTGCCTGCTCTCTGTGGAATCA CCACACAGACACATTCCTGCAAGAAGTTTCTTCTGGCAATGAAGCTGCAATTTTGAGTTCACTAGAACGAACACTGCTATCATTGAAAGT GCTGCGTAAGTTAACTGTTAATGGATTTGTGGAACCTCATAAGAATATGGAGGTGATGGGTTTTTTACATGGAATATTTGAACGTCTAAA ACAGTTTCTGGAATGCATGGCCACAGATGTCTTTAATTCCAAAAACCTGGCCGTTCAGGCACAAAAGAAGATCTTGGGTAAAATGGTGTC CAAATCCATCGCCACCACCTTAATAGACGACACAAGTAGTGAGGTGCTGGATGAGCTCTACAGAGTGACCAGGGAGTACACCCAAAACAA GAAGGAGGCAGAGAAGATCATCAAGAACCTCATCAAGACAGTCATCAAGCTGGCCATTCTTTATAGGAATAATCAGTTTAATCAAGATGA GCTAGCATTGATGGAGAAATTTAAGAAGAAAGTTCATCAGCTTGCTATGACCGTGGTCAGTTTCCATCAGGTGGATTATACCTTTGACCG GAATGTGTTATCCAGGCTGTTAAATGAATGCAGAGAGATGCTGCACCAAATCATTCAGCGCCACCTCACTGCCAAGTCACATGGACGGGT TAATAATGTGTTTGATCATTTTTCAGATTGTGAATTTTTGGCTGCCTTGTATAATCCTTTTGGGAATTTTAAACCCCACTTACAAAAACT ATGTGATGGTATCAACAAAATGTTGGATGAAGAGAACATATGAGCACATGAGTTAAGATTGTGACTGATCATGATTTATTTGAAGATGGA GCACTGCTGATTTATGAAGGAAAAAAGAAGAATTTTCTAAAGATTACACATATTTCAGAAAGACTTTACCCAATTCAGTTGTCAGACATA ATGATTTATTTGAAGGCTTGTTTTATTTGAAGAAAAGCATATTGCCAAAAATTCTGGTTAAAAGCTTCCTAACGGGTAACAGACCATGGG AGAGATATGTGGTTGGGTAATGCAAATGTAGTTATACAAAGAAAAATACAGATGTCTCCAGACCTGAGGACTTTTTAATAGGGCAGTTGT TGTGTTGGTGGCACATTGGATATTTCTAACATGTACAAAGCTATGTATTTTGATTTACTTTCATTTCTTGCTATGTATATGTACTTTTCT TAAAATGCCAAGAACTTTCTCTTGCTATCATTGCTCCTTTTGAAACAATTCAATTTTCATGTCTACAGCTGACTGTTTTGTTAAGATTGA GTCATCGACATTCAGGATTTAAGTCTGAGGTAGTCAACCCTCAGGAAAAAAAAAATGGCTTATCTGAAATCAGTACTGTGGAAATGAACT ATATTAGCTATTATGAATAATGTCCAGTATAAGAATATGCTTCTGGAATTGAGTTCTCCTTTTAAGTACCAATGATACTTAAATTTCTCA GAAATGTAATGGTGTGTCATTGCCTTGAAATGCTTGCTTAGGGCTTCTTTTATGTTATCTTAAAAAGTGCTGGTGAATTTTCCATTTTTT ACATCCATTTCACATGTAAGAGACAAAAAAGTCTAGATTGGTCTTGATATTGAGATAATAAAAAGTAAGTAGCATTAAGAAAGGTAACAA TCTTCATTCTACAGATGAACTCATTGAAACAATTTAGGGGAATGAGGGGCAAAAGGGGAGAAATACTGCTAAAGAACATGAGCATAAAAA TGCGTGCGTTTCAGTGTTTAAGAAGGCTTGATAAAGAATGTCACTTTTTTATTTAACTGATAAGATTTTTGTTATTTTTTACTTTGATAA GTAAACCAAAGAATATTTGTATTTCAAGCAGTTTGTGTGGTGTTTCTATATAATTTTCTGTGTATAAATAATAAAGTAGGCATTTGTTTA TTTTGTAAAAAAGAAATGAAAATCTGCTGGCCAGCTATGTCCTCTAGGAAATGACAGACCCAACCACCAGCAATAAACATTTCCATTGTC >In-frame_IPO11_ENST00000409296_chr5_61770291_+_TNFAIP8_ENST00000504642_chr5_118728511_+_1638nt ATAGCACCAGGTGTGAAACTGCTGGGTCATAGAAGATACAGTCACGAGTTGCTTAAGGCTGGGATACATCCTGAGAAATGGGTCGTTAGG CAATTTTGTTGTTCTATGAACATCATATGAACAAACCTAGATGGTACAGCCTATTATACACTTGGGCTATGTGGTATATAGCTTATTGTA TCTAGGCTATAAGCCTGTACAGCATGTTACTGCACTGAATACTGTAAGCAGTTGTCACAAAATGGTTTCCATGGATCTCAATAGTGCCAG CACTGTTGTTCTTCAGGTGTTAACACAGGCCACCAGTCAGGATACTGCTGTGTTAAAACCAGCTGAGGAGCAGTTGAAGCAGTGGGAGAC ACAGCCAGGTTTCTATTCAGTGTTGCTGAATATTTTCACCAACCACACTTTGGATATAAATGTAAGGTGGCTTGCTGTACTGTATTTTAA ACATGGAATTGATCGCTACTGGAGACGTGTAGCACCTCATGCTCTCTCAGAGGAGGAGAAAACTACTCTGCGTGCAGGGCTCATCACCAA CTTCAATGAACCAATAAACCAGATTGCAACTCAGATTGCAGTGCTCATTGCAAAAGTTGCTAGATTGGATTGTCCCAGACAGTGGCCTGA ACTAATTCCCACTCTTATAGAGTCTGTTAAAGTCCAGGATGATCTTCGACAGCACAGAGCATTACTTACCTTCTATCATGTTACCAAGAC ACTGGCATCTAAACGACTTGCTGCTGATAGAAAACTATTTTATGATTTAGCTTCTGGAATTTATAATTTTGCCTGCTCTCTGTGGAATCA CCACACAGACACATTCCTGCAAGAAGTTTCTTCTGGCAATGAAGCTGCAATTTTGAGTTCACTAGAACGAACACTGCTATCATTGAAAGT GCTGCGTAAGTTAACTGTTAATGGATTTGTGGAACCTCATAAGAATATGGAGGTGATGGGTTTTTTACATGGAATATTTGAACGTCTAAA ACAGTTTCTGGAATGCATGGCCACAGATGTCTTTAATTCCAAAAACCTGGCCGTTCAGGCACAAAAGAAGATCTTGGGTAAAATGGTGTC CAAATCCATCGCCACCACCTTAATAGACGACACAAGTAGTGAGGTGCTGGATGAGCTCTACAGAGTGACCAGGGAGTACACCCAAAACAA GAAGGAGGCAGAGAAGATCATCAAGAACCTCATCAAGACAGTCATCAAGCTGGCCATTCTTTATAGGAATAATCAGTTTAATCAAGATGA GCTAGCATTGATGGAGAAATTTAAGAAGAAAGTTCATCAGCTTGCTATGACCGTGGTCAGTTTCCATCAGGTGGATTATACCTTTGACCG GAATGTGTTATCCAGGCTGTTAAATGAATGCAGAGAGATGCTGCACCAAATCATTCAGCGCCACCTCACTGCCAAGTCACATGGACGGGT TAATAATGTGTTTGATCATTTTTCAGATTGTGAATTTTTGGCTGCCTTGTATAATCCTTTTGGGAATTTTAAACCCCACTTACAAAAACT ATGTGATGGTATCAACAAAATGTTGGATGAAGAGAACATATGAGCACATGAGTTAAGATTGTGACTGATCATGATTTATTTGAAGATGGA |
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FusionGenePPI for IPO11_TNFAIP8 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| IPO11 | TRAF2, PLCD4, C20orf24, RPL12, DDX5, KEAP1, RAN, UBE2E1, UBE2E3, UBE2E2, NXF1, SH3GL2, CFTR, PHB, EGFR, FBXO6, MOB1A, MOB1B, AARS, CACYBP, DR1, EIF4A3, HNRNPD, HNRNPH1, AGFG1, ARPC1B, CALU, HSF1, LPP, METTL1, TPD52L2, TTLL12, UBE3A, PDLIM5, PKM, PLIN3, PRDX2, RANGAP1, SRP9, TPRKB, EIF4A2, C1orf94, ADORA3, COMTD1, BSG, TNFSF13B, PNKD, LPAR6, P2RY12, PTGER3, ARL13B, SCN2B, XPO1, NTRK1, CEP128, SIGLECL1, IL13RA2, HTR2C, FZD10, CHRM4, TMEM206, OPRM1, CD70, SLC15A1, APLNR, STOM, AAR2, TRIM25 | TNFAIP8 | MED4, PTP4A2, PTP4A1, ACOT7, DLD, DPP3, EIF6, HSPA9, IPO5, NHLRC2, PPP1R2, ASS1, ATG3, YWHAE, SDCBP, PRR13, PLEKHF2, TIFA, INO80E, SHMT2, LATS1 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for IPO11_TNFAIP8 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for IPO11_TNFAIP8 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | IPO11 | C0001973 | Alcoholic Intoxication, Chronic | 1 | PSYGENET |
| Hgene | IPO11 | C0043094 | Weight Gain | 1 | CTD_human |
| Tgene | TNFAIP8 | C0023893 | Liver Cirrhosis, Experimental | 1 | CTD_human |
| Tgene | TNFAIP8 | C0027627 | Neoplasm Metastasis | 1 | CTD_human |
| Tgene | TNFAIP8 | C0279626 | Squamous cell carcinoma of esophagus | 1 | CTD_human |
| Tgene | TNFAIP8 | C3495559 | Juvenile arthritis | 1 | CTD_human |
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