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Center for Computational Systems Medicine
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FusionGeneSummary

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FusionGeneSequence

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Fusion gene ID: 17505

FusionGeneSummary for INPP5A_DLG2

check button Fusion gene summary
Fusion gene informationFusion gene name: INPP5A_DLG2
Fusion gene ID: 17505
HgeneTgene
Gene symbol

INPP5A

DLG2

Gene ID

3632

4355

Gene nameinositol polyphosphate-5-phosphatase Amembrane palmitoylated protein 2
Synonyms5PTASEDLG2
Cytomap

10q26.3

17q21.31

Type of geneprotein-codingprotein-coding
Descriptiontype I inositol 1,4,5-trisphosphate 5-phosphatase43 kDa inositol polyphosphate 5-phophataseCTCL tumor antigen HD-CL-02InsP3 5-phosphataseinositol polyphosphate-5-phosphatase, 40kDinositol polyphosphate-5-phosphatase, 40kDainositol trisphosphate-5-phMAGUK p55 subfamily member 2discs large, homolog 2membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)
Modification date2018052320180519
UniProtAcc

Q14642

Q15700

Ensembl transtripts involved in fusion geneENST00000368594, ENST00000368593, 
ENST00000487614, 		ENST00000398309, 
ENST00000376104, ENST00000418306, 
ENST00000280241, ENST00000543673, 
ENST00000376106, ENST00000330014, 
ENST00000537455, ENST00000524982, 
ENST00000532653, ENST00000531015, 
ENST00000398301, ENST00000426717, 
ENST00000404783, ENST00000398304, 
ENST00000530800, ENST00000472545, 
Fusion gene scores* DoF score11 X 6 X 8=52816 X 15 X 6=1440
# samples 1220
** MAII scorelog2(12/528*10)=-2.13750352374993
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(20/1440*10)=-2.84799690655495
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: INPP5A [Title/Abstract] AND DLG2 [Title/Abstract] AND fusion [Title/Abstract]

Functional or gene categories assigned by FusionGDB annotationKinase involved fusion gene, inframe and retained kinase domain.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check button Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
Data typeSourceCancer typeSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
TCGALDBRCATCGA-AR-A0TT-01AINPP5Achr10

134464009

+DLG2chr11

84245774

-
* LD: Li Ding group's fusion gene list
  RV: Roel Verhaak group's fusion gene list
  ChiTaRs fusion database

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000368594ENST00000398309INPP5Achr10

134464009

+DLG2chr11

84245774

-
In-frameENST00000368594ENST00000376104INPP5Achr10

134464009

+DLG2chr11

84245774

-
5CDS-intronENST00000368594ENST00000418306INPP5Achr10

134464009

+DLG2chr11

84245774

-
5CDS-intronENST00000368594ENST00000280241INPP5Achr10

134464009

+DLG2chr11

84245774

-
5CDS-intronENST00000368594ENST00000543673INPP5Achr10

134464009

+DLG2chr11

84245774

-
5CDS-intronENST00000368594ENST00000376106INPP5Achr10

134464009

+DLG2chr11

84245774

-
5CDS-intronENST00000368594ENST00000330014INPP5Achr10

134464009

+DLG2chr11

84245774

-
5CDS-intronENST00000368594ENST00000537455INPP5Achr10

134464009

+DLG2chr11

84245774

-
5CDS-intronENST00000368594ENST00000524982INPP5Achr10

134464009

+DLG2chr11

84245774

-
5CDS-intronENST00000368594ENST00000532653INPP5Achr10

134464009

+DLG2chr11

84245774

-
5CDS-intronENST00000368594ENST00000531015INPP5Achr10

134464009

+DLG2chr11

84245774

-
5CDS-intronENST00000368594ENST00000398301INPP5Achr10

134464009

+DLG2chr11

84245774

-
5CDS-intronENST00000368594ENST00000426717INPP5Achr10

134464009

+DLG2chr11

84245774

-
5CDS-intronENST00000368594ENST00000404783INPP5Achr10

134464009

+DLG2chr11

84245774

-
5CDS-intronENST00000368594ENST00000398304INPP5Achr10

134464009

+DLG2chr11

84245774

-
5CDS-intronENST00000368594ENST00000530800INPP5Achr10

134464009

+DLG2chr11

84245774

-
5CDS-intronENST00000368594ENST00000472545INPP5Achr10

134464009

+DLG2chr11

84245774

-
In-frameENST00000368593ENST00000398309INPP5Achr10

134464009

+DLG2chr11

84245774

-
In-frameENST00000368593ENST00000376104INPP5Achr10

134464009

+DLG2chr11

84245774

-
5CDS-intronENST00000368593ENST00000418306INPP5Achr10

134464009

+DLG2chr11

84245774

-
5CDS-intronENST00000368593ENST00000280241INPP5Achr10

134464009

+DLG2chr11

84245774

-
5CDS-intronENST00000368593ENST00000543673INPP5Achr10

134464009

+DLG2chr11

84245774

-
5CDS-intronENST00000368593ENST00000376106INPP5Achr10

134464009

+DLG2chr11

84245774

-
5CDS-intronENST00000368593ENST00000330014INPP5Achr10

134464009

+DLG2chr11

84245774

-
5CDS-intronENST00000368593ENST00000537455INPP5Achr10

134464009

+DLG2chr11

84245774

-
5CDS-intronENST00000368593ENST00000524982INPP5Achr10

134464009

+DLG2chr11

84245774

-
5CDS-intronENST00000368593ENST00000532653INPP5Achr10

134464009

+DLG2chr11

84245774

-
5CDS-intronENST00000368593ENST00000531015INPP5Achr10

134464009

+DLG2chr11

84245774

-
5CDS-intronENST00000368593ENST00000398301INPP5Achr10

134464009

+DLG2chr11

84245774

-
5CDS-intronENST00000368593ENST00000426717INPP5Achr10

134464009

+DLG2chr11

84245774

-
5CDS-intronENST00000368593ENST00000404783INPP5Achr10

134464009

+DLG2chr11

84245774

-
5CDS-intronENST00000368593ENST00000398304INPP5Achr10

134464009

+DLG2chr11

84245774

-
5CDS-intronENST00000368593ENST00000530800INPP5Achr10

134464009

+DLG2chr11

84245774

-
5CDS-intronENST00000368593ENST00000472545INPP5Achr10

134464009

+DLG2chr11

84245774

-
intron-3CDSENST00000487614ENST00000398309INPP5Achr10

134464009

+DLG2chr11

84245774

-
intron-3CDSENST00000487614ENST00000376104INPP5Achr10

134464009

+DLG2chr11

84245774

-
intron-intronENST00000487614ENST00000418306INPP5Achr10

134464009

+DLG2chr11

84245774

-
intron-intronENST00000487614ENST00000280241INPP5Achr10

134464009

+DLG2chr11

84245774

-
intron-intronENST00000487614ENST00000543673INPP5Achr10

134464009

+DLG2chr11

84245774

-
intron-intronENST00000487614ENST00000376106INPP5Achr10

134464009

+DLG2chr11

84245774

-
intron-intronENST00000487614ENST00000330014INPP5Achr10

134464009

+DLG2chr11

84245774

-
intron-intronENST00000487614ENST00000537455INPP5Achr10

134464009

+DLG2chr11

84245774

-
intron-intronENST00000487614ENST00000524982INPP5Achr10

134464009

+DLG2chr11

84245774

-
intron-intronENST00000487614ENST00000532653INPP5Achr10

134464009

+DLG2chr11

84245774

-
intron-intronENST00000487614ENST00000531015INPP5Achr10

134464009

+DLG2chr11

84245774

-
intron-intronENST00000487614ENST00000398301INPP5Achr10

134464009

+DLG2chr11

84245774

-
intron-intronENST00000487614ENST00000426717INPP5Achr10

134464009

+DLG2chr11

84245774

-
intron-intronENST00000487614ENST00000404783INPP5Achr10

134464009

+DLG2chr11

84245774

-
intron-intronENST00000487614ENST00000398304INPP5Achr10

134464009

+DLG2chr11

84245774

-
intron-intronENST00000487614ENST00000530800INPP5Achr10

134464009

+DLG2chr11

84245774

-
intron-intronENST00000487614ENST00000472545INPP5Achr10

134464009

+DLG2chr11

84245774

-

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FusionProtFeatures for INPP5A_DLG2


check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
INPP5A

Q14642

DLG2

Q15700

Major isoenzyme hydrolyzing the calcium-mobilizingsecond messenger Ins(1,4,5)P3, this is a signal-terminatingreaction. Required for perception of chronic pain through NMDAreceptor signaling. Regulates surface expression of NMDA receptorsin dorsal horn neurons of the spinal cord. Interacts with thecytoplasmic tail of NMDA receptor subunits as well as inwardrectifying potassium channels. Involved in regulation of synapticstability at cholinergic synapses. Part of the postsynapticprotein scaffold of excitatory synapses (By similarity).{ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

.

* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneDLG2chr10:134464009chr11:84245774ENST00000280241-022193_2790910DomainPDZ 2
TgeneDLG2chr10:134464009chr11:84245774ENST00000280241-022421_5010910DomainPDZ 3
TgeneDLG2chr10:134464009chr11:84245774ENST00000280241-022536_6060910DomainSH3
TgeneDLG2chr10:134464009chr11:84245774ENST00000280241-022680_8550910DomainGuanylate kinase-like
TgeneDLG2chr10:134464009chr11:84245774ENST00000280241-02298_1840910DomainPDZ 1
TgeneDLG2chr10:134464009chr11:84245774ENST00000376104-528193_279119976DomainPDZ 2
TgeneDLG2chr10:134464009chr11:84245774ENST00000376104-528421_501119976DomainPDZ 3
TgeneDLG2chr10:134464009chr11:84245774ENST00000376104-528536_606119976DomainSH3
TgeneDLG2chr10:134464009chr11:84245774ENST00000376104-528680_855119976DomainGuanylate kinase-like
TgeneDLG2chr10:134464009chr11:84245774ENST00000376106-022193_279-463335DomainPDZ 2
TgeneDLG2chr10:134464009chr11:84245774ENST00000376106-022421_501-463335DomainPDZ 3
TgeneDLG2chr10:134464009chr11:84245774ENST00000376106-022536_606-463335DomainSH3
TgeneDLG2chr10:134464009chr11:84245774ENST00000376106-022680_855-463335DomainGuanylate kinase-like
TgeneDLG2chr10:134464009chr11:84245774ENST00000376106-02298_184-463335DomainPDZ 1
TgeneDLG2chr10:134464009chr11:84245774ENST00000398309-023193_27914871DomainPDZ 2
TgeneDLG2chr10:134464009chr11:84245774ENST00000398309-023421_50114871DomainPDZ 3
TgeneDLG2chr10:134464009chr11:84245774ENST00000398309-023536_60614871DomainSH3
TgeneDLG2chr10:134464009chr11:84245774ENST00000398309-023680_85514871DomainGuanylate kinase-like
TgeneDLG2chr10:134464009chr11:84245774ENST00000398309-02398_18414871DomainPDZ 1
TgeneDLG2chr10:134464009chr11:84245774ENST00000418306-020193_279-9750DomainPDZ 2
TgeneDLG2chr10:134464009chr11:84245774ENST00000418306-020421_501-9750DomainPDZ 3
TgeneDLG2chr10:134464009chr11:84245774ENST00000418306-020536_606-9750DomainSH3
TgeneDLG2chr10:134464009chr11:84245774ENST00000418306-020680_855-9750DomainGuanylate kinase-like
TgeneDLG2chr10:134464009chr11:84245774ENST00000418306-02098_184-9750DomainPDZ 1
TgeneDLG2chr10:134464009chr11:84245774ENST00000426717-011193_279-94335DomainPDZ 2
TgeneDLG2chr10:134464009chr11:84245774ENST00000426717-011421_501-94335DomainPDZ 3
TgeneDLG2chr10:134464009chr11:84245774ENST00000426717-011536_606-94335DomainSH3
TgeneDLG2chr10:134464009chr11:84245774ENST00000426717-011680_855-94335DomainGuanylate kinase-like
TgeneDLG2chr10:134464009chr11:84245774ENST00000426717-01198_184-94335DomainPDZ 1
TgeneDLG2chr10:134464009chr11:84245774ENST00000543673-326193_279119976DomainPDZ 2
TgeneDLG2chr10:134464009chr11:84245774ENST00000543673-326421_501119976DomainPDZ 3
TgeneDLG2chr10:134464009chr11:84245774ENST00000543673-326536_606119976DomainSH3
TgeneDLG2chr10:134464009chr11:84245774ENST00000543673-326680_855119976DomainGuanylate kinase-like

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneDLG2chr10:134464009chr11:84245774ENST00000376104-52898_184119976DomainPDZ 1
TgeneDLG2chr10:134464009chr11:84245774ENST00000543673-32698_184119976DomainPDZ 1


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FusionGeneSequence for INPP5A_DLG2


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.
>In-frame_INPP5A_ENST00000368594_chr10_134464009_+_DLG2_ENST00000398309_chr11_84245774_-_959aa
MAGKAAAPGTAVLLVTANVGSLFDDPENLQKNWLREFYQVVHTHKPHFMALHCQEFGGKNYEASMSHVDKFVKELLSSDAMKEYNRARVY
LDENYKSQEHFTKYRYQDEDAPHDHSLPRLTHEVRGPELVHVSEKNLSQIENVHGYVLQSHISPLKASPAPIIVNTDTLDTIPYVNGTEI
EYEFEEITLERGNSGLGFSIAGGTDNPHIGDDPGIFITKIIPGGAAAEDGRLRVNDCILRVNEVDVSEVSHSKAVEALKEAGSIVRLYVR
RRRPILETVVEIKLFKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIDGGAAQKDGRLQVGDRLLMVNNYSLEEVTHEEAVAILKNTSEVV
YLKVGKPTTIYMTDPYGPPDITHSYSPPMENHLLSGNNGTLEYKTSLPPISPGRYSPIPKHMLVDDDYTRPPEPVYSTVNKLCDKPASPR
HYSPVECDKSFLLSAPYSHYHLGLLPDSEMTSHSQHSTATRQPSMTLQRAVSLEGEPRKVVLHKGSTGLGFNIVGGEDGEGIFVSFILAG
GPADLSGELQRGDQILSVNGIDLRGASHEQAAAALKGAGQTVTIIAQYQPEDYARFEAKIHDLREQMMNHSMSSGSGSLRTNQKRSLYVR
AMFDYDKSKDSGLPSQGLSFKYGDILHVINASDDEWWQARRVMLEGDSEEMGVIPSKRRVERKERARLKTVKFNAKPGVIDSKGSFNDKR
KKSFIFSRKFPFYKNKEQSEQETSDPERGQEDLILSYEPVTRQEINYTRPVIILGPMKDRINDDLISEFPDKFGSCVPHTTRPKRDYEVD
GRDYHFVISREQMEKDIQEHKFIEAGQYNDNLYGTSVQSVRFVAERGKHCILDVSGNAIKRLQVAQLYPIAIFIKPRSLEPLMEMNKRLT

>In-frame_INPP5A_ENST00000368594_chr10_134464009_+_DLG2_ENST00000376104_chr11_84245774_-_959aa
MAGKAAAPGTAVLLVTANVGSLFDDPENLQKNWLREFYQVVHTHKPHFMALHCQEFGGKNYEASMSHVDKFVKELLSSDAMKEYNRARVY
LDENYKSQEHFTKYRYQDEDAPHDHSLPRLTHEVRGPELVHVSEKNLSQIENVHGYVLQSHISPLKASPAPIIVNTDTLDTIPYVNGTEI
EYEFEEITLERGNSGLGFSIAGGTDNPHIGDDPGIFITKIIPGGAAAEDGRLRVNDCILRVNEVDVSEVSHSKAVEALKEAGSIVRLYVR
RRRPILETVVEIKLFKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIDGGAAQKDGRLQVGDRLLMVNNYSLEEVTHEEAVAILKNTSEVV
YLKVGKPTTIYMTDPYGPPDITHSYSPPMENHLLSGNNGTLEYKTSLPPISPGRYSPIPKHMLVDDDYTRPPEPVYSTVNKLCDKPASPR
HYSPVECDKSFLLSAPYSHYHLGLLPDSEMTSHSQHSTATRQPSMTLQRAVSLEGEPRKVVLHKGSTGLGFNIVGGEDGEGIFVSFILAG
GPADLSGELQRGDQILSVNGIDLRGASHEQAAAALKGAGQTVTIIAQYQPEDYARFEAKIHDLREQMMNHSMSSGSGSLRTNQKRSLYVR
AMFDYDKSKDSGLPSQGLSFKYGDILHVINASDDEWWQARRVMLEGDSEEMGVIPSKRRVERKERARLKTVKFNAKPGVIDSKGSFNDKR
KKSFIFSRKFPFYKNKEQSEQETSDPERGQEDLILSYEPVTRQEINYTRPVIILGPMKDRINDDLISEFPDKFGSCVPHTTRPKRDYEVD
GRDYHFVISREQMEKDIQEHKFIEAGQYNDNLYGTSVQSVRFVAERGKHCILDVSGNAIKRLQVAQLYPIAIFIKPRSLEPLMEMNKRLT

>In-frame_INPP5A_ENST00000368593_chr10_134464009_+_DLG2_ENST00000398309_chr11_84245774_-_959aa
MAGKAAAPGTAVLLVTANVGSLFDDPENLQKNWLREFYQVVHTHKPHFMALHCQEFGGKNYEASMSHVDKFVKELLSSDAMKEYNRARVY
LDENYKSQEHFTKYRYQDEDAPHDHSLPRLTHEVRGPELVHVSEKNLSQIENVHGYVLQSHISPLKASPAPIIVNTDTLDTIPYVNGTEI
EYEFEEITLERGNSGLGFSIAGGTDNPHIGDDPGIFITKIIPGGAAAEDGRLRVNDCILRVNEVDVSEVSHSKAVEALKEAGSIVRLYVR
RRRPILETVVEIKLFKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIDGGAAQKDGRLQVGDRLLMVNNYSLEEVTHEEAVAILKNTSEVV
YLKVGKPTTIYMTDPYGPPDITHSYSPPMENHLLSGNNGTLEYKTSLPPISPGRYSPIPKHMLVDDDYTRPPEPVYSTVNKLCDKPASPR
HYSPVECDKSFLLSAPYSHYHLGLLPDSEMTSHSQHSTATRQPSMTLQRAVSLEGEPRKVVLHKGSTGLGFNIVGGEDGEGIFVSFILAG
GPADLSGELQRGDQILSVNGIDLRGASHEQAAAALKGAGQTVTIIAQYQPEDYARFEAKIHDLREQMMNHSMSSGSGSLRTNQKRSLYVR
AMFDYDKSKDSGLPSQGLSFKYGDILHVINASDDEWWQARRVMLEGDSEEMGVIPSKRRVERKERARLKTVKFNAKPGVIDSKGSFNDKR
KKSFIFSRKFPFYKNKEQSEQETSDPERGQEDLILSYEPVTRQEINYTRPVIILGPMKDRINDDLISEFPDKFGSCVPHTTRPKRDYEVD
GRDYHFVISREQMEKDIQEHKFIEAGQYNDNLYGTSVQSVRFVAERGKHCILDVSGNAIKRLQVAQLYPIAIFIKPRSLEPLMEMNKRLT

>In-frame_INPP5A_ENST00000368593_chr10_134464009_+_DLG2_ENST00000376104_chr11_84245774_-_959aa
MAGKAAAPGTAVLLVTANVGSLFDDPENLQKNWLREFYQVVHTHKPHFMALHCQEFGGKNYEASMSHVDKFVKELLSSDAMKEYNRARVY
LDENYKSQEHFTKYRYQDEDAPHDHSLPRLTHEVRGPELVHVSEKNLSQIENVHGYVLQSHISPLKASPAPIIVNTDTLDTIPYVNGTEI
EYEFEEITLERGNSGLGFSIAGGTDNPHIGDDPGIFITKIIPGGAAAEDGRLRVNDCILRVNEVDVSEVSHSKAVEALKEAGSIVRLYVR
RRRPILETVVEIKLFKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIDGGAAQKDGRLQVGDRLLMVNNYSLEEVTHEEAVAILKNTSEVV
YLKVGKPTTIYMTDPYGPPDITHSYSPPMENHLLSGNNGTLEYKTSLPPISPGRYSPIPKHMLVDDDYTRPPEPVYSTVNKLCDKPASPR
HYSPVECDKSFLLSAPYSHYHLGLLPDSEMTSHSQHSTATRQPSMTLQRAVSLEGEPRKVVLHKGSTGLGFNIVGGEDGEGIFVSFILAG
GPADLSGELQRGDQILSVNGIDLRGASHEQAAAALKGAGQTVTIIAQYQPEDYARFEAKIHDLREQMMNHSMSSGSGSLRTNQKRSLYVR
AMFDYDKSKDSGLPSQGLSFKYGDILHVINASDDEWWQARRVMLEGDSEEMGVIPSKRRVERKERARLKTVKFNAKPGVIDSKGSFNDKR
KKSFIFSRKFPFYKNKEQSEQETSDPERGQEDLILSYEPVTRQEINYTRPVIILGPMKDRINDDLISEFPDKFGSCVPHTTRPKRDYEVD
GRDYHFVISREQMEKDIQEHKFIEAGQYNDNLYGTSVQSVRFVAERGKHCILDVSGNAIKRLQVAQLYPIAIFIKPRSLEPLMEMNKRLT


* Fusion transcript sequences (only coding sequence (CDS) region).
>In-frame_INPP5A_ENST00000368594_chr10_134464009_+_DLG2_ENST00000398309_chr11_84245774_-_2877nt
ATGGCGGGGAAGGCGGCCGCCCCGGGCACCGCGGTGCTGCTGGTCACGGCCAACGTGGGCTCGCTCTTCGACGACCCAGAAAACCTGCAG
AAGAACTGGCTTCGGGAATTTTACCAGGTCGTGCACACACACAAGCCGCACTTCATGGCCTTGCACTGTCAGGAGTTTGGAGGGAAGAAC
TACGAGGCCTCCATGTCCCACGTGGACAAGTTCGTCAAAGAACTATTGTCGAGTGATGCGATGAAAGAATATAACAGGGCTCGAGTCTAC
CTGGATGAAAACTACAAATCCCAGGAGCACTTCACGAAGTATCGATATCAAGATGAGGACGCTCCACATGATCATTCCTTACCTCGACTA
ACCCACGAAGTAAGAGGCCCAGAACTCGTGCATGTATCAGAAAAGAACCTCTCTCAAATAGAAAATGTCCATGGATATGTCTTGCAGTCT
CATATTTCTCCTCTGAAGGCCAGTCCTGCTCCTATAATTGTCAACACAGATACTTTGGACACAATTCCTTATGTCAATGGGACAGAAATT
GAATATGAATTTGAAGAAATTACACTGGAGAGGGGGAATTCTGGCCTGGGATTCAGTATTGCTGGGGGGACAGATAATCCCCACATTGGA
GATGACCCTGGCATATTTATTACGAAGATTATACCAGGAGGTGCTGCAGCAGAGGATGGCAGACTCAGGGTCAATGATTGTATCTTGCGG
GTGAATGAGGTTGATGTGTCAGAGGTTTCCCACAGTAAAGCGGTGGAAGCCCTGAAGGAAGCAGGGTCTATCGTTCGGCTGTATGTGCGT
AGAAGACGACCTATTTTGGAGACCGTTGTGGAAATCAAACTGTTCAAAGGCCCTAAAGGTTTAGGCTTCAGTATTGCAGGAGGTGTGGGG
AACCAACACATTCCTGGAGACAACAGCATTTATGTAACTAAAATTATAGATGGAGGAGCTGCACAAAAAGATGGAAGGTTGCAAGTAGGA
GATAGACTACTAATGGTAAACAACTACAGTTTAGAAGAAGTAACACACGAAGAGGCAGTAGCAATATTAAAGAACACATCAGAGGTAGTT
TATTTAAAAGTTGGCAAACCCACTACCATTTATATGACTGATCCTTATGGTCCACCTGATATTACTCACTCTTATTCTCCACCAATGGAA
AACCATCTACTCTCTGGCAACAATGGCACTTTAGAATATAAAACCTCCCTGCCACCCATCTCTCCAGGAAGGTACTCACCAATTCCAAAG
CACATGCTTGTTGACGACGACTACACCAGGCCTCCGGAACCTGTTTACAGCACTGTGAACAAACTATGTGATAAGCCTGCTTCTCCCAGG
CACTATTCCCCTGTTGAGTGTGACAAAAGCTTCCTCCTCTCAGCTCCCTATTCCCACTACCACCTAGGCCTGCTACCTGACTCTGAGATG
ACCAGTCATTCCCAACATAGCACCGCAACTCGTCAGCCTTCAATGACTCTCCAACGGGCCGTCTCCCTGGAAGGAGAGCCTCGCAAGGTA
GTCCTGCACAAAGGCTCCACTGGCCTGGGCTTCAACATTGTCGGTGGGGAAGATGGAGAAGGTATTTTTGTGTCCTTCATTCTGGCTGGT
GGACCAGCAGACCTAAGTGGGGAGCTCCAGAGAGGAGACCAGATCCTATCGGTGAATGGCATTGACCTCCGTGGTGCATCCCACGAGCAG
GCAGCTGCTGCACTAAAGGGGGCTGGACAGACAGTGACGATTATAGCACAATATCAACCTGAAGATTACGCTCGATTTGAGGCCAAAATC
CATGACCTACGAGAGCAGATGATGAACCACAGCATGAGCTCCGGGTCCGGATCCCTGCGAACCAATCAGAAACGCTCCCTCTACGTCAGA
GCCATGTTCGACTACGACAAGAGCAAGGACAGTGGGCTGCCAAGTCAAGGACTTAGTTTTAAATATGGAGATATTCTCCACGTTATCAAT
GCCTCTGATGATGAGTGGTGGCAAGCCAGGAGAGTCATGCTGGAGGGAGACAGTGAGGAGATGGGGGTCATCCCCAGCAAAAGGAGGGTG
GAAAGAAAGGAACGTGCCCGATTGAAGACAGTGAAGTTTAATGCCAAACCTGGAGTGATTGATTCGAAAGGGTCATTCAATGACAAGCGT
AAAAAGAGCTTCATCTTTTCACGAAAATTCCCATTCTACAAGAACAAGGAGCAGAGTGAGCAGGAAACCAGTGATCCTGAACGAGGACAA
GAAGACCTCATTCTTTCCTATGAGCCTGTTACAAGGCAGGAAATAAACTACACCCGGCCGGTGATTATCCTGGGGCCCATGAAGGATCGG
ATCAATGACGACTTGATATCTGAATTCCCTGATAAATTTGGCTCCTGTGTGCCTCATACTACGAGGCCAAAGCGAGACTACGAGGTGGAT
GGCAGAGACTATCACTTTGTCATTTCCAGAGAACAAATGGAGAAAGATATCCAAGAGCACAAGTTTATAGAAGCCGGCCAGTACAATGAC
AATTTATATGGAACCAGTGTGCAGTCTGTGAGATTTGTAGCAGAAAGAGGCAAACACTGTATACTTGATGTATCAGGAAATGCTATCAAG
CGGTTACAAGTTGCCCAGCTCTATCCCATTGCCATCTTCATAAAACCCAGGTCTCTGGAACCTCTTATGGAGATGAATAAGCGTCTAACA
GAGGAACAAGCCAAGAAAACCTATGATCGAGCAATTAAGCTAGAACAAGAATTTGGAGAATATTTTACAGCTATTGTCCAAGGAGATACT

>In-frame_INPP5A_ENST00000368594_chr10_134464009_+_DLG2_ENST00000376104_chr11_84245774_-_2877nt
ATGGCGGGGAAGGCGGCCGCCCCGGGCACCGCGGTGCTGCTGGTCACGGCCAACGTGGGCTCGCTCTTCGACGACCCAGAAAACCTGCAG
AAGAACTGGCTTCGGGAATTTTACCAGGTCGTGCACACACACAAGCCGCACTTCATGGCCTTGCACTGTCAGGAGTTTGGAGGGAAGAAC
TACGAGGCCTCCATGTCCCACGTGGACAAGTTCGTCAAAGAACTATTGTCGAGTGATGCGATGAAAGAATATAACAGGGCTCGAGTCTAC
CTGGATGAAAACTACAAATCCCAGGAGCACTTCACGAAGTATCGATATCAAGATGAGGACGCTCCACATGATCATTCCTTACCTCGACTA
ACCCACGAAGTAAGAGGCCCAGAACTCGTGCATGTATCAGAAAAGAACCTCTCTCAAATAGAAAATGTCCATGGATATGTCTTGCAGTCT
CATATTTCTCCTCTGAAGGCCAGTCCTGCTCCTATAATTGTCAACACAGATACTTTGGACACAATTCCTTATGTCAATGGGACAGAAATT
GAATATGAATTTGAAGAAATTACACTGGAGAGGGGGAATTCTGGCCTGGGATTCAGTATTGCTGGGGGGACAGATAATCCCCACATTGGA
GATGACCCTGGCATATTTATTACGAAGATTATACCAGGAGGTGCTGCAGCAGAGGATGGCAGACTCAGGGTCAATGATTGTATCTTGCGG
GTGAATGAGGTTGATGTGTCAGAGGTTTCCCACAGTAAAGCGGTGGAAGCCCTGAAGGAAGCAGGGTCTATCGTTCGGCTGTATGTGCGT
AGAAGACGACCTATTTTGGAGACCGTTGTGGAAATCAAACTGTTCAAAGGCCCTAAAGGTTTAGGCTTCAGTATTGCAGGAGGTGTGGGG
AACCAACACATTCCTGGAGACAACAGCATTTATGTAACTAAAATTATAGATGGAGGAGCTGCACAAAAAGATGGAAGGTTGCAAGTAGGA
GATAGACTACTAATGGTAAACAACTACAGTTTAGAAGAAGTAACACACGAAGAGGCAGTAGCAATATTAAAGAACACATCAGAGGTAGTT
TATTTAAAAGTTGGCAAACCCACTACCATTTATATGACTGATCCTTATGGTCCACCTGATATTACTCACTCTTATTCTCCACCAATGGAA
AACCATCTACTCTCTGGCAACAATGGCACTTTAGAATATAAAACCTCCCTGCCACCCATCTCTCCAGGAAGGTACTCACCAATTCCAAAG
CACATGCTTGTTGACGACGACTACACCAGGCCTCCGGAACCTGTTTACAGCACTGTGAACAAACTATGTGATAAGCCTGCTTCTCCCAGG
CACTATTCCCCTGTTGAGTGTGACAAAAGCTTCCTCCTCTCAGCTCCCTATTCCCACTACCACCTAGGCCTGCTACCTGACTCTGAGATG
ACCAGTCATTCCCAACATAGCACCGCAACTCGTCAGCCTTCAATGACTCTCCAACGGGCCGTCTCCCTGGAAGGAGAGCCTCGCAAGGTA
GTCCTGCACAAAGGCTCCACTGGCCTGGGCTTCAACATTGTCGGTGGGGAAGATGGAGAAGGTATTTTTGTGTCCTTCATTCTGGCTGGT
GGACCAGCAGACCTAAGTGGGGAGCTCCAGAGAGGAGACCAGATCCTATCGGTGAATGGCATTGACCTCCGTGGTGCATCCCACGAGCAG
GCAGCTGCTGCACTAAAGGGGGCTGGACAGACAGTGACGATTATAGCACAATATCAACCTGAAGATTACGCTCGATTTGAGGCCAAAATC
CATGACCTACGAGAGCAGATGATGAACCACAGCATGAGCTCCGGGTCCGGATCCCTGCGAACCAATCAGAAACGCTCCCTCTACGTCAGA
GCCATGTTCGACTACGACAAGAGCAAGGACAGTGGGCTGCCAAGTCAAGGACTTAGTTTTAAATATGGAGATATTCTCCACGTTATCAAT
GCCTCTGATGATGAGTGGTGGCAAGCCAGGAGAGTCATGCTGGAGGGAGACAGTGAGGAGATGGGGGTCATCCCCAGCAAAAGGAGGGTG
GAAAGAAAGGAACGTGCCCGATTGAAGACAGTGAAGTTTAATGCCAAACCTGGAGTGATTGATTCGAAAGGGTCATTCAATGACAAGCGT
AAAAAGAGCTTCATCTTTTCACGAAAATTCCCATTCTACAAGAACAAGGAGCAGAGTGAGCAGGAAACCAGTGATCCTGAACGAGGACAA
GAAGACCTCATTCTTTCCTATGAGCCTGTTACAAGGCAGGAAATAAACTACACCCGGCCGGTGATTATCCTGGGGCCCATGAAGGATCGG
ATCAATGACGACTTGATATCTGAATTCCCTGATAAATTTGGCTCCTGTGTGCCTCATACTACGAGGCCAAAGCGAGACTACGAGGTGGAT
GGCAGAGACTATCACTTTGTCATTTCCAGAGAACAAATGGAGAAAGATATCCAAGAGCACAAGTTTATAGAAGCCGGCCAGTACAATGAC
AATTTATATGGAACCAGTGTGCAGTCTGTGAGATTTGTAGCAGAAAGAGGCAAACACTGTATACTTGATGTATCAGGAAATGCTATCAAG
CGGTTACAAGTTGCCCAGCTCTATCCCATTGCCATCTTCATAAAACCCAGGTCTCTGGAACCTCTTATGGAGATGAATAAGCGTCTAACA
GAGGAACAAGCCAAGAAAACCTATGATCGAGCAATTAAGCTAGAACAAGAATTTGGAGAATATTTTACAGCTATTGTCCAAGGAGATACT

>In-frame_INPP5A_ENST00000368593_chr10_134464009_+_DLG2_ENST00000398309_chr11_84245774_-_2877nt
ATGGCGGGGAAGGCGGCCGCCCCGGGCACCGCGGTGCTGCTGGTCACGGCCAACGTGGGCTCGCTCTTCGACGACCCAGAAAACCTGCAG
AAGAACTGGCTTCGGGAATTTTACCAGGTCGTGCACACACACAAGCCGCACTTCATGGCCTTGCACTGTCAGGAGTTTGGAGGGAAGAAC
TACGAGGCCTCCATGTCCCACGTGGACAAGTTCGTCAAAGAACTATTGTCGAGTGATGCGATGAAAGAATATAACAGGGCTCGAGTCTAC
CTGGATGAAAACTACAAATCCCAGGAGCACTTCACGAAGTATCGATATCAAGATGAGGACGCTCCACATGATCATTCCTTACCTCGACTA
ACCCACGAAGTAAGAGGCCCAGAACTCGTGCATGTATCAGAAAAGAACCTCTCTCAAATAGAAAATGTCCATGGATATGTCTTGCAGTCT
CATATTTCTCCTCTGAAGGCCAGTCCTGCTCCTATAATTGTCAACACAGATACTTTGGACACAATTCCTTATGTCAATGGGACAGAAATT
GAATATGAATTTGAAGAAATTACACTGGAGAGGGGGAATTCTGGCCTGGGATTCAGTATTGCTGGGGGGACAGATAATCCCCACATTGGA
GATGACCCTGGCATATTTATTACGAAGATTATACCAGGAGGTGCTGCAGCAGAGGATGGCAGACTCAGGGTCAATGATTGTATCTTGCGG
GTGAATGAGGTTGATGTGTCAGAGGTTTCCCACAGTAAAGCGGTGGAAGCCCTGAAGGAAGCAGGGTCTATCGTTCGGCTGTATGTGCGT
AGAAGACGACCTATTTTGGAGACCGTTGTGGAAATCAAACTGTTCAAAGGCCCTAAAGGTTTAGGCTTCAGTATTGCAGGAGGTGTGGGG
AACCAACACATTCCTGGAGACAACAGCATTTATGTAACTAAAATTATAGATGGAGGAGCTGCACAAAAAGATGGAAGGTTGCAAGTAGGA
GATAGACTACTAATGGTAAACAACTACAGTTTAGAAGAAGTAACACACGAAGAGGCAGTAGCAATATTAAAGAACACATCAGAGGTAGTT
TATTTAAAAGTTGGCAAACCCACTACCATTTATATGACTGATCCTTATGGTCCACCTGATATTACTCACTCTTATTCTCCACCAATGGAA
AACCATCTACTCTCTGGCAACAATGGCACTTTAGAATATAAAACCTCCCTGCCACCCATCTCTCCAGGAAGGTACTCACCAATTCCAAAG
CACATGCTTGTTGACGACGACTACACCAGGCCTCCGGAACCTGTTTACAGCACTGTGAACAAACTATGTGATAAGCCTGCTTCTCCCAGG
CACTATTCCCCTGTTGAGTGTGACAAAAGCTTCCTCCTCTCAGCTCCCTATTCCCACTACCACCTAGGCCTGCTACCTGACTCTGAGATG
ACCAGTCATTCCCAACATAGCACCGCAACTCGTCAGCCTTCAATGACTCTCCAACGGGCCGTCTCCCTGGAAGGAGAGCCTCGCAAGGTA
GTCCTGCACAAAGGCTCCACTGGCCTGGGCTTCAACATTGTCGGTGGGGAAGATGGAGAAGGTATTTTTGTGTCCTTCATTCTGGCTGGT
GGACCAGCAGACCTAAGTGGGGAGCTCCAGAGAGGAGACCAGATCCTATCGGTGAATGGCATTGACCTCCGTGGTGCATCCCACGAGCAG
GCAGCTGCTGCACTAAAGGGGGCTGGACAGACAGTGACGATTATAGCACAATATCAACCTGAAGATTACGCTCGATTTGAGGCCAAAATC
CATGACCTACGAGAGCAGATGATGAACCACAGCATGAGCTCCGGGTCCGGATCCCTGCGAACCAATCAGAAACGCTCCCTCTACGTCAGA
GCCATGTTCGACTACGACAAGAGCAAGGACAGTGGGCTGCCAAGTCAAGGACTTAGTTTTAAATATGGAGATATTCTCCACGTTATCAAT
GCCTCTGATGATGAGTGGTGGCAAGCCAGGAGAGTCATGCTGGAGGGAGACAGTGAGGAGATGGGGGTCATCCCCAGCAAAAGGAGGGTG
GAAAGAAAGGAACGTGCCCGATTGAAGACAGTGAAGTTTAATGCCAAACCTGGAGTGATTGATTCGAAAGGGTCATTCAATGACAAGCGT
AAAAAGAGCTTCATCTTTTCACGAAAATTCCCATTCTACAAGAACAAGGAGCAGAGTGAGCAGGAAACCAGTGATCCTGAACGAGGACAA
GAAGACCTCATTCTTTCCTATGAGCCTGTTACAAGGCAGGAAATAAACTACACCCGGCCGGTGATTATCCTGGGGCCCATGAAGGATCGG
ATCAATGACGACTTGATATCTGAATTCCCTGATAAATTTGGCTCCTGTGTGCCTCATACTACGAGGCCAAAGCGAGACTACGAGGTGGAT
GGCAGAGACTATCACTTTGTCATTTCCAGAGAACAAATGGAGAAAGATATCCAAGAGCACAAGTTTATAGAAGCCGGCCAGTACAATGAC
AATTTATATGGAACCAGTGTGCAGTCTGTGAGATTTGTAGCAGAAAGAGGCAAACACTGTATACTTGATGTATCAGGAAATGCTATCAAG
CGGTTACAAGTTGCCCAGCTCTATCCCATTGCCATCTTCATAAAACCCAGGTCTCTGGAACCTCTTATGGAGATGAATAAGCGTCTAACA
GAGGAACAAGCCAAGAAAACCTATGATCGAGCAATTAAGCTAGAACAAGAATTTGGAGAATATTTTACAGCTATTGTCCAAGGAGATACT

>In-frame_INPP5A_ENST00000368593_chr10_134464009_+_DLG2_ENST00000376104_chr11_84245774_-_2877nt
ATGGCGGGGAAGGCGGCCGCCCCGGGCACCGCGGTGCTGCTGGTCACGGCCAACGTGGGCTCGCTCTTCGACGACCCAGAAAACCTGCAG
AAGAACTGGCTTCGGGAATTTTACCAGGTCGTGCACACACACAAGCCGCACTTCATGGCCTTGCACTGTCAGGAGTTTGGAGGGAAGAAC
TACGAGGCCTCCATGTCCCACGTGGACAAGTTCGTCAAAGAACTATTGTCGAGTGATGCGATGAAAGAATATAACAGGGCTCGAGTCTAC
CTGGATGAAAACTACAAATCCCAGGAGCACTTCACGAAGTATCGATATCAAGATGAGGACGCTCCACATGATCATTCCTTACCTCGACTA
ACCCACGAAGTAAGAGGCCCAGAACTCGTGCATGTATCAGAAAAGAACCTCTCTCAAATAGAAAATGTCCATGGATATGTCTTGCAGTCT
CATATTTCTCCTCTGAAGGCCAGTCCTGCTCCTATAATTGTCAACACAGATACTTTGGACACAATTCCTTATGTCAATGGGACAGAAATT
GAATATGAATTTGAAGAAATTACACTGGAGAGGGGGAATTCTGGCCTGGGATTCAGTATTGCTGGGGGGACAGATAATCCCCACATTGGA
GATGACCCTGGCATATTTATTACGAAGATTATACCAGGAGGTGCTGCAGCAGAGGATGGCAGACTCAGGGTCAATGATTGTATCTTGCGG
GTGAATGAGGTTGATGTGTCAGAGGTTTCCCACAGTAAAGCGGTGGAAGCCCTGAAGGAAGCAGGGTCTATCGTTCGGCTGTATGTGCGT
AGAAGACGACCTATTTTGGAGACCGTTGTGGAAATCAAACTGTTCAAAGGCCCTAAAGGTTTAGGCTTCAGTATTGCAGGAGGTGTGGGG
AACCAACACATTCCTGGAGACAACAGCATTTATGTAACTAAAATTATAGATGGAGGAGCTGCACAAAAAGATGGAAGGTTGCAAGTAGGA
GATAGACTACTAATGGTAAACAACTACAGTTTAGAAGAAGTAACACACGAAGAGGCAGTAGCAATATTAAAGAACACATCAGAGGTAGTT
TATTTAAAAGTTGGCAAACCCACTACCATTTATATGACTGATCCTTATGGTCCACCTGATATTACTCACTCTTATTCTCCACCAATGGAA
AACCATCTACTCTCTGGCAACAATGGCACTTTAGAATATAAAACCTCCCTGCCACCCATCTCTCCAGGAAGGTACTCACCAATTCCAAAG
CACATGCTTGTTGACGACGACTACACCAGGCCTCCGGAACCTGTTTACAGCACTGTGAACAAACTATGTGATAAGCCTGCTTCTCCCAGG
CACTATTCCCCTGTTGAGTGTGACAAAAGCTTCCTCCTCTCAGCTCCCTATTCCCACTACCACCTAGGCCTGCTACCTGACTCTGAGATG
ACCAGTCATTCCCAACATAGCACCGCAACTCGTCAGCCTTCAATGACTCTCCAACGGGCCGTCTCCCTGGAAGGAGAGCCTCGCAAGGTA
GTCCTGCACAAAGGCTCCACTGGCCTGGGCTTCAACATTGTCGGTGGGGAAGATGGAGAAGGTATTTTTGTGTCCTTCATTCTGGCTGGT
GGACCAGCAGACCTAAGTGGGGAGCTCCAGAGAGGAGACCAGATCCTATCGGTGAATGGCATTGACCTCCGTGGTGCATCCCACGAGCAG
GCAGCTGCTGCACTAAAGGGGGCTGGACAGACAGTGACGATTATAGCACAATATCAACCTGAAGATTACGCTCGATTTGAGGCCAAAATC
CATGACCTACGAGAGCAGATGATGAACCACAGCATGAGCTCCGGGTCCGGATCCCTGCGAACCAATCAGAAACGCTCCCTCTACGTCAGA
GCCATGTTCGACTACGACAAGAGCAAGGACAGTGGGCTGCCAAGTCAAGGACTTAGTTTTAAATATGGAGATATTCTCCACGTTATCAAT
GCCTCTGATGATGAGTGGTGGCAAGCCAGGAGAGTCATGCTGGAGGGAGACAGTGAGGAGATGGGGGTCATCCCCAGCAAAAGGAGGGTG
GAAAGAAAGGAACGTGCCCGATTGAAGACAGTGAAGTTTAATGCCAAACCTGGAGTGATTGATTCGAAAGGGTCATTCAATGACAAGCGT
AAAAAGAGCTTCATCTTTTCACGAAAATTCCCATTCTACAAGAACAAGGAGCAGAGTGAGCAGGAAACCAGTGATCCTGAACGAGGACAA
GAAGACCTCATTCTTTCCTATGAGCCTGTTACAAGGCAGGAAATAAACTACACCCGGCCGGTGATTATCCTGGGGCCCATGAAGGATCGG
ATCAATGACGACTTGATATCTGAATTCCCTGATAAATTTGGCTCCTGTGTGCCTCATACTACGAGGCCAAAGCGAGACTACGAGGTGGAT
GGCAGAGACTATCACTTTGTCATTTCCAGAGAACAAATGGAGAAAGATATCCAAGAGCACAAGTTTATAGAAGCCGGCCAGTACAATGAC
AATTTATATGGAACCAGTGTGCAGTCTGTGAGATTTGTAGCAGAAAGAGGCAAACACTGTATACTTGATGTATCAGGAAATGCTATCAAG
CGGTTACAAGTTGCCCAGCTCTATCCCATTGCCATCTTCATAAAACCCAGGTCTCTGGAACCTCTTATGGAGATGAATAAGCGTCTAACA
GAGGAACAAGCCAAGAAAACCTATGATCGAGCAATTAAGCTAGAACAAGAATTTGGAGAATATTTTACAGCTATTGTCCAAGGAGATACT


* Fusion transcript sequences (Full-length transcript).
>In-frame_INPP5A_ENST00000368594_chr10_134464009_+_DLG2_ENST00000398309_chr11_84245774_-_7960nt
GGAACTTTCCCAGCGGATCTAATGGCTGCGCGCGGGCCGCTGTGAGGCGCGGCGGCGAGCGACGGGCGCGGGGCCGCGGAGCAGCGAGCG
AGCGAGCGAGCGCGAGGCCGGAGCCCCGGCCAGGCCCGGCCGACCCGCCGAGCCCGCGATGCGCCCCGGGGCCGCCCCCCGGCGCAGCTG
ACGCCCCGCGGCCCCGCGAAGACCCCGGCCGGCCGGTCCCGGAGGAAGCGGCCGCCGCCGCCGCCGCCCAGCCCAGCGCCCGCGCCGCCC
GGGCACCATGGCGGGGAAGGCGGCCGCCCCGGGCACCGCGGTGCTGCTGGTCACGGCCAACGTGGGCTCGCTCTTCGACGACCCAGAAAA
CCTGCAGAAGAACTGGCTTCGGGAATTTTACCAGGTCGTGCACACACACAAGCCGCACTTCATGGCCTTGCACTGTCAGGAGTTTGGAGG
GAAGAACTACGAGGCCTCCATGTCCCACGTGGACAAGTTCGTCAAAGAACTATTGTCGAGTGATGCGATGAAAGAATATAACAGGGCTCG
AGTCTACCTGGATGAAAACTACAAATCCCAGGAGCACTTCACGAAGTATCGATATCAAGATGAGGACGCTCCACATGATCATTCCTTACC
TCGACTAACCCACGAAGTAAGAGGCCCAGAACTCGTGCATGTATCAGAAAAGAACCTCTCTCAAATAGAAAATGTCCATGGATATGTCTT
GCAGTCTCATATTTCTCCTCTGAAGGCCAGTCCTGCTCCTATAATTGTCAACACAGATACTTTGGACACAATTCCTTATGTCAATGGGAC
AGAAATTGAATATGAATTTGAAGAAATTACACTGGAGAGGGGGAATTCTGGCCTGGGATTCAGTATTGCTGGGGGGACAGATAATCCCCA
CATTGGAGATGACCCTGGCATATTTATTACGAAGATTATACCAGGAGGTGCTGCAGCAGAGGATGGCAGACTCAGGGTCAATGATTGTAT
CTTGCGGGTGAATGAGGTTGATGTGTCAGAGGTTTCCCACAGTAAAGCGGTGGAAGCCCTGAAGGAAGCAGGGTCTATCGTTCGGCTGTA
TGTGCGTAGAAGACGACCTATTTTGGAGACCGTTGTGGAAATCAAACTGTTCAAAGGCCCTAAAGGTTTAGGCTTCAGTATTGCAGGAGG
TGTGGGGAACCAACACATTCCTGGAGACAACAGCATTTATGTAACTAAAATTATAGATGGAGGAGCTGCACAAAAAGATGGAAGGTTGCA
AGTAGGAGATAGACTACTAATGGTAAACAACTACAGTTTAGAAGAAGTAACACACGAAGAGGCAGTAGCAATATTAAAGAACACATCAGA
GGTAGTTTATTTAAAAGTTGGCAAACCCACTACCATTTATATGACTGATCCTTATGGTCCACCTGATATTACTCACTCTTATTCTCCACC
AATGGAAAACCATCTACTCTCTGGCAACAATGGCACTTTAGAATATAAAACCTCCCTGCCACCCATCTCTCCAGGAAGGTACTCACCAAT
TCCAAAGCACATGCTTGTTGACGACGACTACACCAGGCCTCCGGAACCTGTTTACAGCACTGTGAACAAACTATGTGATAAGCCTGCTTC
TCCCAGGCACTATTCCCCTGTTGAGTGTGACAAAAGCTTCCTCCTCTCAGCTCCCTATTCCCACTACCACCTAGGCCTGCTACCTGACTC
TGAGATGACCAGTCATTCCCAACATAGCACCGCAACTCGTCAGCCTTCAATGACTCTCCAACGGGCCGTCTCCCTGGAAGGAGAGCCTCG
CAAGGTAGTCCTGCACAAAGGCTCCACTGGCCTGGGCTTCAACATTGTCGGTGGGGAAGATGGAGAAGGTATTTTTGTGTCCTTCATTCT
GGCTGGTGGACCAGCAGACCTAAGTGGGGAGCTCCAGAGAGGAGACCAGATCCTATCGGTGAATGGCATTGACCTCCGTGGTGCATCCCA
CGAGCAGGCAGCTGCTGCACTAAAGGGGGCTGGACAGACAGTGACGATTATAGCACAATATCAACCTGAAGATTACGCTCGATTTGAGGC
CAAAATCCATGACCTACGAGAGCAGATGATGAACCACAGCATGAGCTCCGGGTCCGGATCCCTGCGAACCAATCAGAAACGCTCCCTCTA
CGTCAGAGCCATGTTCGACTACGACAAGAGCAAGGACAGTGGGCTGCCAAGTCAAGGACTTAGTTTTAAATATGGAGATATTCTCCACGT
TATCAATGCCTCTGATGATGAGTGGTGGCAAGCCAGGAGAGTCATGCTGGAGGGAGACAGTGAGGAGATGGGGGTCATCCCCAGCAAAAG
GAGGGTGGAAAGAAAGGAACGTGCCCGATTGAAGACAGTGAAGTTTAATGCCAAACCTGGAGTGATTGATTCGAAAGGGTCATTCAATGA
CAAGCGTAAAAAGAGCTTCATCTTTTCACGAAAATTCCCATTCTACAAGAACAAGGAGCAGAGTGAGCAGGAAACCAGTGATCCTGAACG
AGGACAAGAAGACCTCATTCTTTCCTATGAGCCTGTTACAAGGCAGGAAATAAACTACACCCGGCCGGTGATTATCCTGGGGCCCATGAA
GGATCGGATCAATGACGACTTGATATCTGAATTCCCTGATAAATTTGGCTCCTGTGTGCCTCATACTACGAGGCCAAAGCGAGACTACGA
GGTGGATGGCAGAGACTATCACTTTGTCATTTCCAGAGAACAAATGGAGAAAGATATCCAAGAGCACAAGTTTATAGAAGCCGGCCAGTA
CAATGACAATTTATATGGAACCAGTGTGCAGTCTGTGAGATTTGTAGCAGAAAGAGGCAAACACTGTATACTTGATGTATCAGGAAATGC
TATCAAGCGGTTACAAGTTGCCCAGCTCTATCCCATTGCCATCTTCATAAAACCCAGGTCTCTGGAACCTCTTATGGAGATGAATAAGCG
TCTAACAGAGGAACAAGCCAAGAAAACCTATGATCGAGCAATTAAGCTAGAACAAGAATTTGGAGAATATTTTACAGCTATTGTCCAAGG
AGATACTTTAGAAGATATATATAACCAATGCAAGCTTGTTATTGAAGAGCAATCTGGGCCTTTCATCTGGATTCCCTCAAAGGAAAAGTT
ATAAATTAGCTACTGCGCCTCTGACAACGACAGAAGAGCATTTAGAAGAACAAAATATATATAACATACTACTTGGAGGCTTTTATGTTT
TTGTTGCATTTATGTTTTTGCAGTCAATGTGAATTCTTACGAATGTACAACACAAACTGTATGAAGCCATGAAGGAAACAGAGGGGCCAA
AGGGTGGGACAGAAAAGACATTGCAGTATGAAGGAAGGCTTTGGTTTGCTCAAAGTGCCAGGTGTAGGGATGAACCTCTGACGGGCTTTC
TGCCCAAGAGATGAGATGAGAGCCTCCTCACCCCAGCAGATGTCCAGAGCTGATTTAGCTGCAGAGCTCTCTGTGTCTTTTGCTTTAAAG
AAAAATTGCCAGCACTCGAACCTCATCAGCCTTCCCATTACCCACATCTGTAATTGGTACACTTTGAATTTTATAACTATGCACATCTTT
TGATTTCTTAACAAGCAAATGAAAGAAAGAAGGAAAAAAGAAAGGAATCCCTTTGGAGATGACATACTATCAGGGAAGGATAAGTGTGTA
GTTTTTTGACTGGCATCTGCAAAGACAAGAATTTCATAAAATTTGCAAGTGTATGGAGGACTAACCTCACTGACAGGAGGGGATTCCACC
TGGGATTAGCTTTATGATTGTTGATTGCCTATTTTGCCATTTATAAACTGAAAGAAGGCACTAAAGATGAGAATAATTTATACAATAAAA
ATATATTAAATGTATAGAAACAAATTTCTATAGGTTAAAAAAGTTTTGTGAAATATTTTGTAAAGACTAATATTGAAAGACTAAATGTAT
GCAACATCAGCAGATGATCAAATTCAAGACCTGAAAGTTGCACTCTCCCTTTTGTTGCCAATGATCTGTTAAGAGCATCTGAGTTCCTTT
TAAGTCTGACAAAGACTTCTTCCTCACTTACCTCCCTTCCACATTAGTGATACACTCTCATGCAGCACATCCCTTAATGAGTTGCCCTCA
TGGATATTTTTGGAAGACATTTGGTTAATGCATTTTTTTATGCTGATGGCTTTTCAGAGACAAACTTATGCAAATGATCTAAAGGGAAGT
TTTTGCTTTCCTCTAGTTAAATAACCTGAGCCTGCCATGCAAATAGTTGAATAACTTTGTTCCTAGTTACTGACATACAATTCTTAAAGG
ACCATTTAGCATTTTGGCCAACAATGAGTAATTAGGATTAGTACCTTTTTGTTTTACAGAGTAACTGAGAGTTTTGTAACATCCAGAGAT
GGTACTAGAGCCAATGAGAGATCTGTTCCTAGATGCACTATTTCTTTGAGGAAGAGAGAGAAGAGAAGTGTCTGGTTGGGGGTGAGGGGG
TGCAGACTTTTTTGTTTCTATGTACAGAGCAAAGAGATAGAGTCACAAGGAAAGACAATTAATGACTTTGAGCTCAACCAACTGAACTGC
CTTTCTTGGAGCTGCACCTGGACCAAGTTTATTTTTTAACAATTATAATAACGATGATTTAAAAAAAGAAACCTCCCAAAGCCTATAAAC
TGAACTAGAAGAGTTGGTTTCCCACTTTAGAGTGGATGGCGACATCAGCATTGCTTTTGCCCATGGTGTTTGGGGAGAGACTTTTCAGTG
ATAATAACCACTCTACTCTGGGTTCTGTGCATGCCCAGACTAAGCCCCATCGCCTTATTTCTGGGGTACATCCAGACCTGGCAGGGATTC
TGCCACACTGTGCAGCAAACCAGCATGTAGGCTGGGTAGGAGAGCAAGAGATAGAGCCATCAGAGTGATGGGGCTTCTTCACAGTAAGAA
CATCGGAGCTTAGAATGAGAGTCTCTTTCCAAAAACAGGCATTGTTCATCTTACGCTAAACATCATTGTCTGCCTGGCTACAGTCACCAA
AACAAAACAGAAATGCAAAATTATGCATCTTCCCATAGTCCTGAGGCTTCCTTTGCCAATGGAAGGGCTAGCAATGCATTCTCCCTCTCA
TGAAAGTTAAATTTCCAGAGACTTCCTTAGATTGCTCAAAATGTTAAAGATATGTCCATGTCTGCAATTCGCCAGTTTCAGGTCAAGGCC
TACTTTCATCAATATTGCTCCCAGAAGTTTTCTGACACCAGAATGCCATTCCTGATCCCAGCTCTATTTTTAGGCCACCACGATAACTTC
TTTGGTTTCTCAACTGAGCATGCAACCATTTATTTAAAAGACTGTCATTAATGAGTAGATGTTTTCGCGGGTCGTGTGATGTGCTTTCCA
TTTACTAGTGTTGCTGTGGCTAAGTACAATCAAATTGAACCACCAACCCTTGGTTTTGTAGTAATATAACTATTTATTTTCCTAGTGTAG
ATGCTTTCAGATTAGAATTGGCATTTGCACTGATTTTTTTATGTAGATTTATATAAATATATAGATACATATATATTTGCTTGAAGAATC
ACCAAGCAAATTGGTGAGAGGGTCTTTTCCAATAGAATTTACACCTCCATTTGTTGTGTTGTCTTGCACTTCCCAATGTTGATGTCTCTA
TGGCTCCAATGAACTGGTGTATTTTGCAGCAAATCTGATGACTTGTATGGAAATGGCATGAAAGTTACCCAGATTACATCTGGTGCAAAT
GCACTCGGAGCCTGGGGCCAGACTGGTGCTAACACTGCAAACTTTGTCCAGAGCTCTCTCCAACCTGAAGGCTTGCTGGGGGTGCAATGT
CACCTTCACACATGCTGGGCCCTTTCAGAAAAGTGCCAGATCGTGTAACTGGTGCTATTTTTCATGCTCTGGTACAATGTGTAGCACCAC
GGGGGTCTCAGCTTTACCAAAATCAAAATTCCATTTGTCAGCTAAGTGCAGAGGCATTTGTTTTTTGCTCTCCTCCCACAGAATTGTCGG
CCATTTATTTGCAGGCCTTTTGCGGGATTTCTTGGCTATTTATTTGCAGGCCTTTTTTCCCAGCCCCAAATTCTTGGGTTGGCTCTGTCT
GCTTAAAGAGCCTGTCTTCACAAAGCTGCACTCGGGTGCCTCTGTGCGCTGTCTTAGATCCTACTGCCGGCCCTTCAGGACTCCGAGCCA
GGAAAGAACTCTCCAACCTCTGGCTCGAGACTCTACTTTTTTTCTCATTCTTTTCCTTACTCTCCTCCTCCTTCTACTTCCGACTAATTC
CATCTCTTTTTTTTTTTGTTCCTCTCCTTTTCCTATTCCTCCTTCCCACCATCTCTGAGTTGTTGACTTTCTCCTATAATCCTTCTCTAT
TCCCTTTCTCTTTTTGTCCACCTCTCCTTTAGTCTCTGTTTCTCTGCCCTTCTTATTCCTCTTCTGTCCTTTCTCCTCTCCTCAAATCTC
TGATCATCTTCTCCCGTACATCCCTGTATTGATTTTTCTGTCCTCTAAAGGGCTCATGGCTGATTCAGACAGCAAGTCCATGCACTGGAC
TAATGACACAAATACTTTAGGTCGCCGTTTCACCTACTCAGCCCAGAAAGTAAAGCTGAGCGTGAGGCCCTGACCTGGAGCCTGCTCCAG
CCCGCCTCCCGGAGCCAGCCTGCACCGTTGCCCTGGCAGCGATGATGCATGTGCTGTGGGCCCTGCCGGCGCCTGAGTGCCTCTGCCTGA
ACACTGCTCCTAAGCGAGCCCACTCCCAGCACTACCGCATGGCTCTGAGGACATTTTCTTTCAATAAAGGCAGACTCTGGCCCCAATTAT
TCTGATAGCAAACCTCTTCCTCCTCATTGAAGCCATGCCATCACCTTGGTTTGGAGAGAGACATTTTTTTCCCATTCATAAGCTTTCTTT
TTCCCATTTTTATGTGAAGCCCCCTCTGCTTTTCAGCTGGTGATTGCTCTGGTGAGACTGAATGGACTTGCTGGTGAAATGAAATCTCTT
CTTTCCTGTCTTGGTCCTGCCTAAATTCCTACAAATATATTTAAGCCAAGGACTCAGGCTAATTCCTAAGTTGATCACATTAATTTGTTA
CTCCTAGAGGGAAAAAGATCAATTCCCTTGAAGCATGTGGAGTACCTCCTGTGACAGCTGACTTGCCAGGGGACTCCCTACAGAATTCTG
TGATATACATTTTACTTCTGTGTATGTATGGTATATATGGTATGTATACCATGTACACACGTTACATTGAGTATGAATGACTGTGGTTGG
AAACACACACACACACTCAAGTCTGTAAATATCCTTCCTCACTGAAACCTGTGCTTTGGAAATCATTTCTTGTACAGCTGTGCAGTTTCT
TGTAACAGCTGAGGACAAAGCTAAGACAGGCGGACAATTTAGACAAAGATCATCTAAAGAGTATAGTATCTCCCTAGCAACTCATGAGGA
CAGACAACCAAGTGGCAAGGTTGACTCCCAATGGGATGGCAGACTTTTCTTCTCTCCTTTTTGAGTTTGTGTTTCCTAAGTGTTTCTTAA
CTTCTGAGTGCACCAGGCTGTACCCGTTAGATCCTTTCAATATGACAGTTTTGTGCTTCTCTCTGACAGGATGTTTCTCCACCGAGCTGT
AGCACAGGATGGGAGGGAGGTGGGAATACTCCTTGCCTAGGCTGGAGTTTACAGAGACACTGCACAGCTTACACTCCTGTTAAGTGTAAA
TATTCAACACTTCCATTCCATTTGTGTAAAAAATAAAGCACACACGATTATAAAATCAAGATGTATATTTCATACTCAGTGTGTCTGTGC
ATATTTATTGCGTTTCTAGTTGTCAGCGGTGGGTGGCCCCATTGTAAAAATGCCTGATAGAGTGTTTATAAACATGTCATGGTTTTATTA

>In-frame_INPP5A_ENST00000368594_chr10_134464009_+_DLG2_ENST00000376104_chr11_84245774_-_5053nt
GGAACTTTCCCAGCGGATCTAATGGCTGCGCGCGGGCCGCTGTGAGGCGCGGCGGCGAGCGACGGGCGCGGGGCCGCGGAGCAGCGAGCG
AGCGAGCGAGCGCGAGGCCGGAGCCCCGGCCAGGCCCGGCCGACCCGCCGAGCCCGCGATGCGCCCCGGGGCCGCCCCCCGGCGCAGCTG
ACGCCCCGCGGCCCCGCGAAGACCCCGGCCGGCCGGTCCCGGAGGAAGCGGCCGCCGCCGCCGCCGCCCAGCCCAGCGCCCGCGCCGCCC
GGGCACCATGGCGGGGAAGGCGGCCGCCCCGGGCACCGCGGTGCTGCTGGTCACGGCCAACGTGGGCTCGCTCTTCGACGACCCAGAAAA
CCTGCAGAAGAACTGGCTTCGGGAATTTTACCAGGTCGTGCACACACACAAGCCGCACTTCATGGCCTTGCACTGTCAGGAGTTTGGAGG
GAAGAACTACGAGGCCTCCATGTCCCACGTGGACAAGTTCGTCAAAGAACTATTGTCGAGTGATGCGATGAAAGAATATAACAGGGCTCG
AGTCTACCTGGATGAAAACTACAAATCCCAGGAGCACTTCACGAAGTATCGATATCAAGATGAGGACGCTCCACATGATCATTCCTTACC
TCGACTAACCCACGAAGTAAGAGGCCCAGAACTCGTGCATGTATCAGAAAAGAACCTCTCTCAAATAGAAAATGTCCATGGATATGTCTT
GCAGTCTCATATTTCTCCTCTGAAGGCCAGTCCTGCTCCTATAATTGTCAACACAGATACTTTGGACACAATTCCTTATGTCAATGGGAC
AGAAATTGAATATGAATTTGAAGAAATTACACTGGAGAGGGGGAATTCTGGCCTGGGATTCAGTATTGCTGGGGGGACAGATAATCCCCA
CATTGGAGATGACCCTGGCATATTTATTACGAAGATTATACCAGGAGGTGCTGCAGCAGAGGATGGCAGACTCAGGGTCAATGATTGTAT
CTTGCGGGTGAATGAGGTTGATGTGTCAGAGGTTTCCCACAGTAAAGCGGTGGAAGCCCTGAAGGAAGCAGGGTCTATCGTTCGGCTGTA
TGTGCGTAGAAGACGACCTATTTTGGAGACCGTTGTGGAAATCAAACTGTTCAAAGGCCCTAAAGGTTTAGGCTTCAGTATTGCAGGAGG
TGTGGGGAACCAACACATTCCTGGAGACAACAGCATTTATGTAACTAAAATTATAGATGGAGGAGCTGCACAAAAAGATGGAAGGTTGCA
AGTAGGAGATAGACTACTAATGGTAAACAACTACAGTTTAGAAGAAGTAACACACGAAGAGGCAGTAGCAATATTAAAGAACACATCAGA
GGTAGTTTATTTAAAAGTTGGCAAACCCACTACCATTTATATGACTGATCCTTATGGTCCACCTGATATTACTCACTCTTATTCTCCACC
AATGGAAAACCATCTACTCTCTGGCAACAATGGCACTTTAGAATATAAAACCTCCCTGCCACCCATCTCTCCAGGAAGGTACTCACCAAT
TCCAAAGCACATGCTTGTTGACGACGACTACACCAGGCCTCCGGAACCTGTTTACAGCACTGTGAACAAACTATGTGATAAGCCTGCTTC
TCCCAGGCACTATTCCCCTGTTGAGTGTGACAAAAGCTTCCTCCTCTCAGCTCCCTATTCCCACTACCACCTAGGCCTGCTACCTGACTC
TGAGATGACCAGTCATTCCCAACATAGCACCGCAACTCGTCAGCCTTCAATGACTCTCCAACGGGCCGTCTCCCTGGAAGGAGAGCCTCG
CAAGGTAGTCCTGCACAAAGGCTCCACTGGCCTGGGCTTCAACATTGTCGGTGGGGAAGATGGAGAAGGTATTTTTGTGTCCTTCATTCT
GGCTGGTGGACCAGCAGACCTAAGTGGGGAGCTCCAGAGAGGAGACCAGATCCTATCGGTGAATGGCATTGACCTCCGTGGTGCATCCCA
CGAGCAGGCAGCTGCTGCACTAAAGGGGGCTGGACAGACAGTGACGATTATAGCACAATATCAACCTGAAGATTACGCTCGATTTGAGGC
CAAAATCCATGACCTACGAGAGCAGATGATGAACCACAGCATGAGCTCCGGGTCCGGATCCCTGCGAACCAATCAGAAACGCTCCCTCTA
CGTCAGAGCCATGTTCGACTACGACAAGAGCAAGGACAGTGGGCTGCCAAGTCAAGGACTTAGTTTTAAATATGGAGATATTCTCCACGT
TATCAATGCCTCTGATGATGAGTGGTGGCAAGCCAGGAGAGTCATGCTGGAGGGAGACAGTGAGGAGATGGGGGTCATCCCCAGCAAAAG
GAGGGTGGAAAGAAAGGAACGTGCCCGATTGAAGACAGTGAAGTTTAATGCCAAACCTGGAGTGATTGATTCGAAAGGGTCATTCAATGA
CAAGCGTAAAAAGAGCTTCATCTTTTCACGAAAATTCCCATTCTACAAGAACAAGGAGCAGAGTGAGCAGGAAACCAGTGATCCTGAACG
AGGACAAGAAGACCTCATTCTTTCCTATGAGCCTGTTACAAGGCAGGAAATAAACTACACCCGGCCGGTGATTATCCTGGGGCCCATGAA
GGATCGGATCAATGACGACTTGATATCTGAATTCCCTGATAAATTTGGCTCCTGTGTGCCTCATACTACGAGGCCAAAGCGAGACTACGA
GGTGGATGGCAGAGACTATCACTTTGTCATTTCCAGAGAACAAATGGAGAAAGATATCCAAGAGCACAAGTTTATAGAAGCCGGCCAGTA
CAATGACAATTTATATGGAACCAGTGTGCAGTCTGTGAGATTTGTAGCAGAAAGAGGCAAACACTGTATACTTGATGTATCAGGAAATGC
TATCAAGCGGTTACAAGTTGCCCAGCTCTATCCCATTGCCATCTTCATAAAACCCAGGTCTCTGGAACCTCTTATGGAGATGAATAAGCG
TCTAACAGAGGAACAAGCCAAGAAAACCTATGATCGAGCAATTAAGCTAGAACAAGAATTTGGAGAATATTTTACAGCTATTGTCCAAGG
AGATACTTTAGAAGATATATATAACCAATGCAAGCTTGTTATTGAAGAGCAATCTGGGCCTTTCATCTGGATTCCCTCAAAGGAAAAGTT
ATAAATTAGCTACTGCGCCTCTGACAACGACAGAAGAGCATTTAGAAGAACAAAATATATATAACATACTACTTGGAGGCTTTTATGTTT
TTGTTGCATTTATGTTTTTGCAGTCAATGTGAATTCTTACGAATGTACAACACAAACTGTATGAAGCCATGAAGGAAACAGAGGGGCCAA
AGGGTGGGACAGAAAAGACATTGCAGTATGAAGGAAGGCTTTGGTTTGCTCAAAGTGCCAGGTGTAGGGATGAACCTCTGACGGGCTTTC
TGCCCAAGAGATGAGATGAGAGCCTCCTCACCCCAGCAGATGTCCAGAGCTGATTTAGCTGCAGAGCTCTCTGTGTCTTTTGCTTTAAAG
AAAAATTGCCAGCACTCGAACCTCATCAGCCTTCCCATTACCCACATCTGTAATTGGTACACTTTGAATTTTATAACTATGCACATCTTT
TGATTTCTTAACAAGCAAATGAAAGAAAGAAGGAAAAAAGAAAGGAATCCCTTTGGAGATGACATACTATCAGGGAAGGATAAGTGTGTA
GTTTTTTGACTGGCATCTGCAAAGACAAGAATTTCATAAAATTTGCAAGTGTATGGAGGACTAACCTCACTGACAGGAGGGGATTCCACC
TGGGATTAGCTTTATGATTGTTGATTGCCTATTTTGCCATTTATAAACTGAAAGAAGGCACTAAAGATGAGAATAATTTATACAATAAAA
ATATATTAAATGTATAGAAACAAATTTCTATAGGTTAAAAAAGTTTTGTGAAATATTTTGTAAAGACTAATATTGAAAGACTAAATGTAT
GCAACATCAGCAGATGATCAAATTCAAGACCTGAAAGTTGCACTCTCCCTTTTGTTGCCAATGATCTGTTAAGAGCATCTGAGTTCCTTT
TAAGTCTGACAAAGACTTCTTCCTCACTTACCTCCCTTCCACATTAGTGATACACTCTCATGCAGCACATCCCTTAATGAGTTGCCCTCA
TGGATATTTTTGGAAGACATTTGGTTAATGCATTTTTTTATGCTGATGGCTTTTCAGAGACAAACTTATGCAAATGATCTAAAGGGAAGT
TTTTGCTTTCCTCTAGTTAAATAACCTGAGCCTGCCATGCAAATAGTTGAATAACTTTGTTCCTAGTTACTGACATACAATTCTTAAAGG
ACCATTTAGCATTTTGGCCAACAATGAGTAATTAGGATTAGTACCTTTTTGTTTTACAGAGTAACTGAGAGTTTTGTAACATCCAGAGAT
GGTACTAGAGCCAATGAGAGATCTGTTCCTAGATGCACTATTTCTTTGAGGAAGAGAGAGAAGAGAAGTGTCTGGTTGGGGGTGAGGGGG
TGCAGACTTTTTTGTTTCTATGTACAGAGCAAAGAGATAGAGTCACAAGGAAAGACAATTAATGACTTTGAGCTCAACCAACTGAACTGC
CTTTCTTGGAGCTGCACCTGGACCAAGTTTATTTTTTAACAATTATAATAACGATGATTTAAAAAAAGAAACCTCCCAAAGCCTATAAAC
TGAACTAGAAGAGTTGGTTTCCCACTTTAGAGTGGATGGCGACATCAGCATTGCTTTTGCCCATGGTGTTTGGGGAGAGACTTTTCAGTG
ATAATAACCACTCTACTCTGGGTTCTGTGCATGCCCAGACTAAGCCCCATCGCCTTATTTCTGGGGTACATCCAGACCTGGCAGGGATTC
TGCCACACTGTGCAGCAAACCAGCATGTAGGCTGGGTAGGAGAGCAAGAGATAGAGCCATCAGAGTGATGGGGCTTCTTCACAGTAAGAA
CATCGGAGCTTAGAATGAGAGTCTCTTTCCAAAAACAGGCATTGTTCATCTTACGCTAAACATCATTGTCTGCCTGGCTACAGTCACCAA

>In-frame_INPP5A_ENST00000368593_chr10_134464009_+_DLG2_ENST00000398309_chr11_84245774_-_7931nt
GCGCGGGCCGCTGTGAGGCGCGGCGGCGAGCGACGGGCGCGGGGCCGCGGAGCAGCGAGCGAGCGAGCGAGCGCGAGGCCGGAGCCCCGG
CCAGGCCCGGCCGACCCGCCGAGCCCGCGATGCGCCCCGGGGCCGCCCCCCGGCGCAGCTGACGCCCCGCGGCCCCGCGAAGACCCCGGC
CGGCCGGTCCCGGAGGAAGCGGCCGCCGCCGCCGCCGCCCAGCCCAGCGCCCGCGCCGCCCGGGCACCATGGCGGGGAAGGCGGCCGCCC
CGGGCACCGCGGTGCTGCTGGTCACGGCCAACGTGGGCTCGCTCTTCGACGACCCAGAAAACCTGCAGAAGAACTGGCTTCGGGAATTTT
ACCAGGTCGTGCACACACACAAGCCGCACTTCATGGCCTTGCACTGTCAGGAGTTTGGAGGGAAGAACTACGAGGCCTCCATGTCCCACG
TGGACAAGTTCGTCAAAGAACTATTGTCGAGTGATGCGATGAAAGAATATAACAGGGCTCGAGTCTACCTGGATGAAAACTACAAATCCC
AGGAGCACTTCACGAAGTATCGATATCAAGATGAGGACGCTCCACATGATCATTCCTTACCTCGACTAACCCACGAAGTAAGAGGCCCAG
AACTCGTGCATGTATCAGAAAAGAACCTCTCTCAAATAGAAAATGTCCATGGATATGTCTTGCAGTCTCATATTTCTCCTCTGAAGGCCA
GTCCTGCTCCTATAATTGTCAACACAGATACTTTGGACACAATTCCTTATGTCAATGGGACAGAAATTGAATATGAATTTGAAGAAATTA
CACTGGAGAGGGGGAATTCTGGCCTGGGATTCAGTATTGCTGGGGGGACAGATAATCCCCACATTGGAGATGACCCTGGCATATTTATTA
CGAAGATTATACCAGGAGGTGCTGCAGCAGAGGATGGCAGACTCAGGGTCAATGATTGTATCTTGCGGGTGAATGAGGTTGATGTGTCAG
AGGTTTCCCACAGTAAAGCGGTGGAAGCCCTGAAGGAAGCAGGGTCTATCGTTCGGCTGTATGTGCGTAGAAGACGACCTATTTTGGAGA
CCGTTGTGGAAATCAAACTGTTCAAAGGCCCTAAAGGTTTAGGCTTCAGTATTGCAGGAGGTGTGGGGAACCAACACATTCCTGGAGACA
ACAGCATTTATGTAACTAAAATTATAGATGGAGGAGCTGCACAAAAAGATGGAAGGTTGCAAGTAGGAGATAGACTACTAATGGTAAACA
ACTACAGTTTAGAAGAAGTAACACACGAAGAGGCAGTAGCAATATTAAAGAACACATCAGAGGTAGTTTATTTAAAAGTTGGCAAACCCA
CTACCATTTATATGACTGATCCTTATGGTCCACCTGATATTACTCACTCTTATTCTCCACCAATGGAAAACCATCTACTCTCTGGCAACA
ATGGCACTTTAGAATATAAAACCTCCCTGCCACCCATCTCTCCAGGAAGGTACTCACCAATTCCAAAGCACATGCTTGTTGACGACGACT
ACACCAGGCCTCCGGAACCTGTTTACAGCACTGTGAACAAACTATGTGATAAGCCTGCTTCTCCCAGGCACTATTCCCCTGTTGAGTGTG
ACAAAAGCTTCCTCCTCTCAGCTCCCTATTCCCACTACCACCTAGGCCTGCTACCTGACTCTGAGATGACCAGTCATTCCCAACATAGCA
CCGCAACTCGTCAGCCTTCAATGACTCTCCAACGGGCCGTCTCCCTGGAAGGAGAGCCTCGCAAGGTAGTCCTGCACAAAGGCTCCACTG
GCCTGGGCTTCAACATTGTCGGTGGGGAAGATGGAGAAGGTATTTTTGTGTCCTTCATTCTGGCTGGTGGACCAGCAGACCTAAGTGGGG
AGCTCCAGAGAGGAGACCAGATCCTATCGGTGAATGGCATTGACCTCCGTGGTGCATCCCACGAGCAGGCAGCTGCTGCACTAAAGGGGG
CTGGACAGACAGTGACGATTATAGCACAATATCAACCTGAAGATTACGCTCGATTTGAGGCCAAAATCCATGACCTACGAGAGCAGATGA
TGAACCACAGCATGAGCTCCGGGTCCGGATCCCTGCGAACCAATCAGAAACGCTCCCTCTACGTCAGAGCCATGTTCGACTACGACAAGA
GCAAGGACAGTGGGCTGCCAAGTCAAGGACTTAGTTTTAAATATGGAGATATTCTCCACGTTATCAATGCCTCTGATGATGAGTGGTGGC
AAGCCAGGAGAGTCATGCTGGAGGGAGACAGTGAGGAGATGGGGGTCATCCCCAGCAAAAGGAGGGTGGAAAGAAAGGAACGTGCCCGAT
TGAAGACAGTGAAGTTTAATGCCAAACCTGGAGTGATTGATTCGAAAGGGTCATTCAATGACAAGCGTAAAAAGAGCTTCATCTTTTCAC
GAAAATTCCCATTCTACAAGAACAAGGAGCAGAGTGAGCAGGAAACCAGTGATCCTGAACGAGGACAAGAAGACCTCATTCTTTCCTATG
AGCCTGTTACAAGGCAGGAAATAAACTACACCCGGCCGGTGATTATCCTGGGGCCCATGAAGGATCGGATCAATGACGACTTGATATCTG
AATTCCCTGATAAATTTGGCTCCTGTGTGCCTCATACTACGAGGCCAAAGCGAGACTACGAGGTGGATGGCAGAGACTATCACTTTGTCA
TTTCCAGAGAACAAATGGAGAAAGATATCCAAGAGCACAAGTTTATAGAAGCCGGCCAGTACAATGACAATTTATATGGAACCAGTGTGC
AGTCTGTGAGATTTGTAGCAGAAAGAGGCAAACACTGTATACTTGATGTATCAGGAAATGCTATCAAGCGGTTACAAGTTGCCCAGCTCT
ATCCCATTGCCATCTTCATAAAACCCAGGTCTCTGGAACCTCTTATGGAGATGAATAAGCGTCTAACAGAGGAACAAGCCAAGAAAACCT
ATGATCGAGCAATTAAGCTAGAACAAGAATTTGGAGAATATTTTACAGCTATTGTCCAAGGAGATACTTTAGAAGATATATATAACCAAT
GCAAGCTTGTTATTGAAGAGCAATCTGGGCCTTTCATCTGGATTCCCTCAAAGGAAAAGTTATAAATTAGCTACTGCGCCTCTGACAACG
ACAGAAGAGCATTTAGAAGAACAAAATATATATAACATACTACTTGGAGGCTTTTATGTTTTTGTTGCATTTATGTTTTTGCAGTCAATG
TGAATTCTTACGAATGTACAACACAAACTGTATGAAGCCATGAAGGAAACAGAGGGGCCAAAGGGTGGGACAGAAAAGACATTGCAGTAT
GAAGGAAGGCTTTGGTTTGCTCAAAGTGCCAGGTGTAGGGATGAACCTCTGACGGGCTTTCTGCCCAAGAGATGAGATGAGAGCCTCCTC
ACCCCAGCAGATGTCCAGAGCTGATTTAGCTGCAGAGCTCTCTGTGTCTTTTGCTTTAAAGAAAAATTGCCAGCACTCGAACCTCATCAG
CCTTCCCATTACCCACATCTGTAATTGGTACACTTTGAATTTTATAACTATGCACATCTTTTGATTTCTTAACAAGCAAATGAAAGAAAG
AAGGAAAAAAGAAAGGAATCCCTTTGGAGATGACATACTATCAGGGAAGGATAAGTGTGTAGTTTTTTGACTGGCATCTGCAAAGACAAG
AATTTCATAAAATTTGCAAGTGTATGGAGGACTAACCTCACTGACAGGAGGGGATTCCACCTGGGATTAGCTTTATGATTGTTGATTGCC
TATTTTGCCATTTATAAACTGAAAGAAGGCACTAAAGATGAGAATAATTTATACAATAAAAATATATTAAATGTATAGAAACAAATTTCT
ATAGGTTAAAAAAGTTTTGTGAAATATTTTGTAAAGACTAATATTGAAAGACTAAATGTATGCAACATCAGCAGATGATCAAATTCAAGA
CCTGAAAGTTGCACTCTCCCTTTTGTTGCCAATGATCTGTTAAGAGCATCTGAGTTCCTTTTAAGTCTGACAAAGACTTCTTCCTCACTT
ACCTCCCTTCCACATTAGTGATACACTCTCATGCAGCACATCCCTTAATGAGTTGCCCTCATGGATATTTTTGGAAGACATTTGGTTAAT
GCATTTTTTTATGCTGATGGCTTTTCAGAGACAAACTTATGCAAATGATCTAAAGGGAAGTTTTTGCTTTCCTCTAGTTAAATAACCTGA
GCCTGCCATGCAAATAGTTGAATAACTTTGTTCCTAGTTACTGACATACAATTCTTAAAGGACCATTTAGCATTTTGGCCAACAATGAGT
AATTAGGATTAGTACCTTTTTGTTTTACAGAGTAACTGAGAGTTTTGTAACATCCAGAGATGGTACTAGAGCCAATGAGAGATCTGTTCC
TAGATGCACTATTTCTTTGAGGAAGAGAGAGAAGAGAAGTGTCTGGTTGGGGGTGAGGGGGTGCAGACTTTTTTGTTTCTATGTACAGAG
CAAAGAGATAGAGTCACAAGGAAAGACAATTAATGACTTTGAGCTCAACCAACTGAACTGCCTTTCTTGGAGCTGCACCTGGACCAAGTT
TATTTTTTAACAATTATAATAACGATGATTTAAAAAAAGAAACCTCCCAAAGCCTATAAACTGAACTAGAAGAGTTGGTTTCCCACTTTA
GAGTGGATGGCGACATCAGCATTGCTTTTGCCCATGGTGTTTGGGGAGAGACTTTTCAGTGATAATAACCACTCTACTCTGGGTTCTGTG
CATGCCCAGACTAAGCCCCATCGCCTTATTTCTGGGGTACATCCAGACCTGGCAGGGATTCTGCCACACTGTGCAGCAAACCAGCATGTA
GGCTGGGTAGGAGAGCAAGAGATAGAGCCATCAGAGTGATGGGGCTTCTTCACAGTAAGAACATCGGAGCTTAGAATGAGAGTCTCTTTC
CAAAAACAGGCATTGTTCATCTTACGCTAAACATCATTGTCTGCCTGGCTACAGTCACCAAAACAAAACAGAAATGCAAAATTATGCATC
TTCCCATAGTCCTGAGGCTTCCTTTGCCAATGGAAGGGCTAGCAATGCATTCTCCCTCTCATGAAAGTTAAATTTCCAGAGACTTCCTTA
GATTGCTCAAAATGTTAAAGATATGTCCATGTCTGCAATTCGCCAGTTTCAGGTCAAGGCCTACTTTCATCAATATTGCTCCCAGAAGTT
TTCTGACACCAGAATGCCATTCCTGATCCCAGCTCTATTTTTAGGCCACCACGATAACTTCTTTGGTTTCTCAACTGAGCATGCAACCAT
TTATTTAAAAGACTGTCATTAATGAGTAGATGTTTTCGCGGGTCGTGTGATGTGCTTTCCATTTACTAGTGTTGCTGTGGCTAAGTACAA
TCAAATTGAACCACCAACCCTTGGTTTTGTAGTAATATAACTATTTATTTTCCTAGTGTAGATGCTTTCAGATTAGAATTGGCATTTGCA
CTGATTTTTTTATGTAGATTTATATAAATATATAGATACATATATATTTGCTTGAAGAATCACCAAGCAAATTGGTGAGAGGGTCTTTTC
CAATAGAATTTACACCTCCATTTGTTGTGTTGTCTTGCACTTCCCAATGTTGATGTCTCTATGGCTCCAATGAACTGGTGTATTTTGCAG
CAAATCTGATGACTTGTATGGAAATGGCATGAAAGTTACCCAGATTACATCTGGTGCAAATGCACTCGGAGCCTGGGGCCAGACTGGTGC
TAACACTGCAAACTTTGTCCAGAGCTCTCTCCAACCTGAAGGCTTGCTGGGGGTGCAATGTCACCTTCACACATGCTGGGCCCTTTCAGA
AAAGTGCCAGATCGTGTAACTGGTGCTATTTTTCATGCTCTGGTACAATGTGTAGCACCACGGGGGTCTCAGCTTTACCAAAATCAAAAT
TCCATTTGTCAGCTAAGTGCAGAGGCATTTGTTTTTTGCTCTCCTCCCACAGAATTGTCGGCCATTTATTTGCAGGCCTTTTGCGGGATT
TCTTGGCTATTTATTTGCAGGCCTTTTTTCCCAGCCCCAAATTCTTGGGTTGGCTCTGTCTGCTTAAAGAGCCTGTCTTCACAAAGCTGC
ACTCGGGTGCCTCTGTGCGCTGTCTTAGATCCTACTGCCGGCCCTTCAGGACTCCGAGCCAGGAAAGAACTCTCCAACCTCTGGCTCGAG
ACTCTACTTTTTTTCTCATTCTTTTCCTTACTCTCCTCCTCCTTCTACTTCCGACTAATTCCATCTCTTTTTTTTTTTGTTCCTCTCCTT
TTCCTATTCCTCCTTCCCACCATCTCTGAGTTGTTGACTTTCTCCTATAATCCTTCTCTATTCCCTTTCTCTTTTTGTCCACCTCTCCTT
TAGTCTCTGTTTCTCTGCCCTTCTTATTCCTCTTCTGTCCTTTCTCCTCTCCTCAAATCTCTGATCATCTTCTCCCGTACATCCCTGTAT
TGATTTTTCTGTCCTCTAAAGGGCTCATGGCTGATTCAGACAGCAAGTCCATGCACTGGACTAATGACACAAATACTTTAGGTCGCCGTT
TCACCTACTCAGCCCAGAAAGTAAAGCTGAGCGTGAGGCCCTGACCTGGAGCCTGCTCCAGCCCGCCTCCCGGAGCCAGCCTGCACCGTT
GCCCTGGCAGCGATGATGCATGTGCTGTGGGCCCTGCCGGCGCCTGAGTGCCTCTGCCTGAACACTGCTCCTAAGCGAGCCCACTCCCAG
CACTACCGCATGGCTCTGAGGACATTTTCTTTCAATAAAGGCAGACTCTGGCCCCAATTATTCTGATAGCAAACCTCTTCCTCCTCATTG
AAGCCATGCCATCACCTTGGTTTGGAGAGAGACATTTTTTTCCCATTCATAAGCTTTCTTTTTCCCATTTTTATGTGAAGCCCCCTCTGC
TTTTCAGCTGGTGATTGCTCTGGTGAGACTGAATGGACTTGCTGGTGAAATGAAATCTCTTCTTTCCTGTCTTGGTCCTGCCTAAATTCC
TACAAATATATTTAAGCCAAGGACTCAGGCTAATTCCTAAGTTGATCACATTAATTTGTTACTCCTAGAGGGAAAAAGATCAATTCCCTT
GAAGCATGTGGAGTACCTCCTGTGACAGCTGACTTGCCAGGGGACTCCCTACAGAATTCTGTGATATACATTTTACTTCTGTGTATGTAT
GGTATATATGGTATGTATACCATGTACACACGTTACATTGAGTATGAATGACTGTGGTTGGAAACACACACACACACTCAAGTCTGTAAA
TATCCTTCCTCACTGAAACCTGTGCTTTGGAAATCATTTCTTGTACAGCTGTGCAGTTTCTTGTAACAGCTGAGGACAAAGCTAAGACAG
GCGGACAATTTAGACAAAGATCATCTAAAGAGTATAGTATCTCCCTAGCAACTCATGAGGACAGACAACCAAGTGGCAAGGTTGACTCCC
AATGGGATGGCAGACTTTTCTTCTCTCCTTTTTGAGTTTGTGTTTCCTAAGTGTTTCTTAACTTCTGAGTGCACCAGGCTGTACCCGTTA
GATCCTTTCAATATGACAGTTTTGTGCTTCTCTCTGACAGGATGTTTCTCCACCGAGCTGTAGCACAGGATGGGAGGGAGGTGGGAATAC
TCCTTGCCTAGGCTGGAGTTTACAGAGACACTGCACAGCTTACACTCCTGTTAAGTGTAAATATTCAACACTTCCATTCCATTTGTGTAA
AAAATAAAGCACACACGATTATAAAATCAAGATGTATATTTCATACTCAGTGTGTCTGTGCATATTTATTGCGTTTCTAGTTGTCAGCGG
TGGGTGGCCCCATTGTAAAAATGCCTGATAGAGTGTTTATAAACATGTCATGGTTTTATTATAAGATATAAATATTAAAACATTTTATAC

>In-frame_INPP5A_ENST00000368593_chr10_134464009_+_DLG2_ENST00000376104_chr11_84245774_-_5024nt
GCGCGGGCCGCTGTGAGGCGCGGCGGCGAGCGACGGGCGCGGGGCCGCGGAGCAGCGAGCGAGCGAGCGAGCGCGAGGCCGGAGCCCCGG
CCAGGCCCGGCCGACCCGCCGAGCCCGCGATGCGCCCCGGGGCCGCCCCCCGGCGCAGCTGACGCCCCGCGGCCCCGCGAAGACCCCGGC
CGGCCGGTCCCGGAGGAAGCGGCCGCCGCCGCCGCCGCCCAGCCCAGCGCCCGCGCCGCCCGGGCACCATGGCGGGGAAGGCGGCCGCCC
CGGGCACCGCGGTGCTGCTGGTCACGGCCAACGTGGGCTCGCTCTTCGACGACCCAGAAAACCTGCAGAAGAACTGGCTTCGGGAATTTT
ACCAGGTCGTGCACACACACAAGCCGCACTTCATGGCCTTGCACTGTCAGGAGTTTGGAGGGAAGAACTACGAGGCCTCCATGTCCCACG
TGGACAAGTTCGTCAAAGAACTATTGTCGAGTGATGCGATGAAAGAATATAACAGGGCTCGAGTCTACCTGGATGAAAACTACAAATCCC
AGGAGCACTTCACGAAGTATCGATATCAAGATGAGGACGCTCCACATGATCATTCCTTACCTCGACTAACCCACGAAGTAAGAGGCCCAG
AACTCGTGCATGTATCAGAAAAGAACCTCTCTCAAATAGAAAATGTCCATGGATATGTCTTGCAGTCTCATATTTCTCCTCTGAAGGCCA
GTCCTGCTCCTATAATTGTCAACACAGATACTTTGGACACAATTCCTTATGTCAATGGGACAGAAATTGAATATGAATTTGAAGAAATTA
CACTGGAGAGGGGGAATTCTGGCCTGGGATTCAGTATTGCTGGGGGGACAGATAATCCCCACATTGGAGATGACCCTGGCATATTTATTA
CGAAGATTATACCAGGAGGTGCTGCAGCAGAGGATGGCAGACTCAGGGTCAATGATTGTATCTTGCGGGTGAATGAGGTTGATGTGTCAG
AGGTTTCCCACAGTAAAGCGGTGGAAGCCCTGAAGGAAGCAGGGTCTATCGTTCGGCTGTATGTGCGTAGAAGACGACCTATTTTGGAGA
CCGTTGTGGAAATCAAACTGTTCAAAGGCCCTAAAGGTTTAGGCTTCAGTATTGCAGGAGGTGTGGGGAACCAACACATTCCTGGAGACA
ACAGCATTTATGTAACTAAAATTATAGATGGAGGAGCTGCACAAAAAGATGGAAGGTTGCAAGTAGGAGATAGACTACTAATGGTAAACA
ACTACAGTTTAGAAGAAGTAACACACGAAGAGGCAGTAGCAATATTAAAGAACACATCAGAGGTAGTTTATTTAAAAGTTGGCAAACCCA
CTACCATTTATATGACTGATCCTTATGGTCCACCTGATATTACTCACTCTTATTCTCCACCAATGGAAAACCATCTACTCTCTGGCAACA
ATGGCACTTTAGAATATAAAACCTCCCTGCCACCCATCTCTCCAGGAAGGTACTCACCAATTCCAAAGCACATGCTTGTTGACGACGACT
ACACCAGGCCTCCGGAACCTGTTTACAGCACTGTGAACAAACTATGTGATAAGCCTGCTTCTCCCAGGCACTATTCCCCTGTTGAGTGTG
ACAAAAGCTTCCTCCTCTCAGCTCCCTATTCCCACTACCACCTAGGCCTGCTACCTGACTCTGAGATGACCAGTCATTCCCAACATAGCA
CCGCAACTCGTCAGCCTTCAATGACTCTCCAACGGGCCGTCTCCCTGGAAGGAGAGCCTCGCAAGGTAGTCCTGCACAAAGGCTCCACTG
GCCTGGGCTTCAACATTGTCGGTGGGGAAGATGGAGAAGGTATTTTTGTGTCCTTCATTCTGGCTGGTGGACCAGCAGACCTAAGTGGGG
AGCTCCAGAGAGGAGACCAGATCCTATCGGTGAATGGCATTGACCTCCGTGGTGCATCCCACGAGCAGGCAGCTGCTGCACTAAAGGGGG
CTGGACAGACAGTGACGATTATAGCACAATATCAACCTGAAGATTACGCTCGATTTGAGGCCAAAATCCATGACCTACGAGAGCAGATGA
TGAACCACAGCATGAGCTCCGGGTCCGGATCCCTGCGAACCAATCAGAAACGCTCCCTCTACGTCAGAGCCATGTTCGACTACGACAAGA
GCAAGGACAGTGGGCTGCCAAGTCAAGGACTTAGTTTTAAATATGGAGATATTCTCCACGTTATCAATGCCTCTGATGATGAGTGGTGGC
AAGCCAGGAGAGTCATGCTGGAGGGAGACAGTGAGGAGATGGGGGTCATCCCCAGCAAAAGGAGGGTGGAAAGAAAGGAACGTGCCCGAT
TGAAGACAGTGAAGTTTAATGCCAAACCTGGAGTGATTGATTCGAAAGGGTCATTCAATGACAAGCGTAAAAAGAGCTTCATCTTTTCAC
GAAAATTCCCATTCTACAAGAACAAGGAGCAGAGTGAGCAGGAAACCAGTGATCCTGAACGAGGACAAGAAGACCTCATTCTTTCCTATG
AGCCTGTTACAAGGCAGGAAATAAACTACACCCGGCCGGTGATTATCCTGGGGCCCATGAAGGATCGGATCAATGACGACTTGATATCTG
AATTCCCTGATAAATTTGGCTCCTGTGTGCCTCATACTACGAGGCCAAAGCGAGACTACGAGGTGGATGGCAGAGACTATCACTTTGTCA
TTTCCAGAGAACAAATGGAGAAAGATATCCAAGAGCACAAGTTTATAGAAGCCGGCCAGTACAATGACAATTTATATGGAACCAGTGTGC
AGTCTGTGAGATTTGTAGCAGAAAGAGGCAAACACTGTATACTTGATGTATCAGGAAATGCTATCAAGCGGTTACAAGTTGCCCAGCTCT
ATCCCATTGCCATCTTCATAAAACCCAGGTCTCTGGAACCTCTTATGGAGATGAATAAGCGTCTAACAGAGGAACAAGCCAAGAAAACCT
ATGATCGAGCAATTAAGCTAGAACAAGAATTTGGAGAATATTTTACAGCTATTGTCCAAGGAGATACTTTAGAAGATATATATAACCAAT
GCAAGCTTGTTATTGAAGAGCAATCTGGGCCTTTCATCTGGATTCCCTCAAAGGAAAAGTTATAAATTAGCTACTGCGCCTCTGACAACG
ACAGAAGAGCATTTAGAAGAACAAAATATATATAACATACTACTTGGAGGCTTTTATGTTTTTGTTGCATTTATGTTTTTGCAGTCAATG
TGAATTCTTACGAATGTACAACACAAACTGTATGAAGCCATGAAGGAAACAGAGGGGCCAAAGGGTGGGACAGAAAAGACATTGCAGTAT
GAAGGAAGGCTTTGGTTTGCTCAAAGTGCCAGGTGTAGGGATGAACCTCTGACGGGCTTTCTGCCCAAGAGATGAGATGAGAGCCTCCTC
ACCCCAGCAGATGTCCAGAGCTGATTTAGCTGCAGAGCTCTCTGTGTCTTTTGCTTTAAAGAAAAATTGCCAGCACTCGAACCTCATCAG
CCTTCCCATTACCCACATCTGTAATTGGTACACTTTGAATTTTATAACTATGCACATCTTTTGATTTCTTAACAAGCAAATGAAAGAAAG
AAGGAAAAAAGAAAGGAATCCCTTTGGAGATGACATACTATCAGGGAAGGATAAGTGTGTAGTTTTTTGACTGGCATCTGCAAAGACAAG
AATTTCATAAAATTTGCAAGTGTATGGAGGACTAACCTCACTGACAGGAGGGGATTCCACCTGGGATTAGCTTTATGATTGTTGATTGCC
TATTTTGCCATTTATAAACTGAAAGAAGGCACTAAAGATGAGAATAATTTATACAATAAAAATATATTAAATGTATAGAAACAAATTTCT
ATAGGTTAAAAAAGTTTTGTGAAATATTTTGTAAAGACTAATATTGAAAGACTAAATGTATGCAACATCAGCAGATGATCAAATTCAAGA
CCTGAAAGTTGCACTCTCCCTTTTGTTGCCAATGATCTGTTAAGAGCATCTGAGTTCCTTTTAAGTCTGACAAAGACTTCTTCCTCACTT
ACCTCCCTTCCACATTAGTGATACACTCTCATGCAGCACATCCCTTAATGAGTTGCCCTCATGGATATTTTTGGAAGACATTTGGTTAAT
GCATTTTTTTATGCTGATGGCTTTTCAGAGACAAACTTATGCAAATGATCTAAAGGGAAGTTTTTGCTTTCCTCTAGTTAAATAACCTGA
GCCTGCCATGCAAATAGTTGAATAACTTTGTTCCTAGTTACTGACATACAATTCTTAAAGGACCATTTAGCATTTTGGCCAACAATGAGT
AATTAGGATTAGTACCTTTTTGTTTTACAGAGTAACTGAGAGTTTTGTAACATCCAGAGATGGTACTAGAGCCAATGAGAGATCTGTTCC
TAGATGCACTATTTCTTTGAGGAAGAGAGAGAAGAGAAGTGTCTGGTTGGGGGTGAGGGGGTGCAGACTTTTTTGTTTCTATGTACAGAG
CAAAGAGATAGAGTCACAAGGAAAGACAATTAATGACTTTGAGCTCAACCAACTGAACTGCCTTTCTTGGAGCTGCACCTGGACCAAGTT
TATTTTTTAACAATTATAATAACGATGATTTAAAAAAAGAAACCTCCCAAAGCCTATAAACTGAACTAGAAGAGTTGGTTTCCCACTTTA
GAGTGGATGGCGACATCAGCATTGCTTTTGCCCATGGTGTTTGGGGAGAGACTTTTCAGTGATAATAACCACTCTACTCTGGGTTCTGTG
CATGCCCAGACTAAGCCCCATCGCCTTATTTCTGGGGTACATCCAGACCTGGCAGGGATTCTGCCACACTGTGCAGCAAACCAGCATGTA
GGCTGGGTAGGAGAGCAAGAGATAGAGCCATCAGAGTGATGGGGCTTCTTCACAGTAAGAACATCGGAGCTTAGAATGAGAGTCTCTTTC


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FusionGenePPI for INPP5A_DLG2


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page

.

check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors
INPP5AYWHAZ, RABGGTB, TTC1, RCCD1, ZG16B, ITFG2, IGHA1, SLC25A41, DUSP22, ISOC2, MED21, PRPS2DLG2LRP2, ERBB4, KCNJ12, KCNJ4, GRIN2B, KCNA4, DLGAP1, DYNLL1, DYNLL2, DLG4, NLGN2, NLGN1, NLGN3, GRIN2A, SEMA4C, NOS1, ATP2B2, ATP2B4, GUCY1A2, KHDRBS1, FASLG, MAP1A


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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RelatedDrugs for INPP5A_DLG2


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for INPP5A_DLG2


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneINPP5AC0007137Squamous cell carcinoma1CTD_human
HgeneINPP5AC0036341Schizophrenia1CTD_human
HgeneINPP5AC0037274Dermatologic disorders1CTD_human
HgeneINPP5AC0311375Arsenic Poisoning1CTD_human
TgeneDLG2C0036341Schizophrenia4PSYGENET
TgeneDLG2C0005586Bipolar Disorder2PSYGENET
TgeneDLG2C0025202melanoma1CTD_human
TgeneDLG2C0041696Unipolar Depression1PSYGENET
TgeneDLG2C0809983Schizophrenia and related disorders1PSYGENET
TgeneDLG2C1269683Major Depressive Disorder1PSYGENET