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Fusion gene ID: 17472 |
FusionGeneSummary for INCENP_CCS |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: INCENP_CCS | Fusion gene ID: 17472 | Hgene | Tgene | Gene symbol | INCENP | CCS | Gene ID | 3619 | 9973 |
| Gene name | inner centromere protein | copper chaperone for superoxide dismutase | |
| Synonyms | - | - | |
| Cytomap | 11q12.3 | 11q13.2 | |
| Type of gene | protein-coding | protein-coding | |
| Description | inner centromere proteinbinds and activates aurora-B and -C in vivo and in vitrochromosomal passenger proteininner centromere protein INCENPinner centromere protein antigens 135/155kDa | copper chaperone for superoxide dismutasesuperoxide dismutase copper chaperone | |
| Modification date | 20180522 | 20180523 | |
| UniProtAcc | Q9NQS7 | O14618 | |
| Ensembl transtripts involved in fusion gene | ENST00000394818, ENST00000278849, ENST00000531099, | ENST00000533244, ENST00000310190, | |
| Fusion gene scores | * DoF score | 2 X 3 X 2=12 | 2 X 2 X 2=8 |
| # samples | 2 | 2 | |
| ** MAII score | log2(2/12*10)=0.736965594166206 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | log2(2/8*10)=1.32192809488736 | |
| Context | PubMed: INCENP [Title/Abstract] AND CCS [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | LUSC | TCGA-77-8153-01A | INCENP | chr11 | 61908983 | + | CCS | chr11 | 66372810 | + |
| TCGA | LD | LUSC | TCGA-77-8153-01A | INCENP | chr11 | 61908516 | + | CCS | chr11 | 66372810 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000394818 | ENST00000533244 | INCENP | chr11 | 61908983 | + | CCS | chr11 | 66372810 | + |
| In-frame | ENST00000394818 | ENST00000310190 | INCENP | chr11 | 61908983 | + | CCS | chr11 | 66372810 | + |
| intron-3CDS | ENST00000278849 | ENST00000533244 | INCENP | chr11 | 61908983 | + | CCS | chr11 | 66372810 | + |
| intron-3CDS | ENST00000278849 | ENST00000310190 | INCENP | chr11 | 61908983 | + | CCS | chr11 | 66372810 | + |
| intron-3CDS | ENST00000531099 | ENST00000533244 | INCENP | chr11 | 61908983 | + | CCS | chr11 | 66372810 | + |
| intron-3CDS | ENST00000531099 | ENST00000310190 | INCENP | chr11 | 61908983 | + | CCS | chr11 | 66372810 | + |
| In-frame | ENST00000394818 | ENST00000533244 | INCENP | chr11 | 61908516 | + | CCS | chr11 | 66372810 | + |
| In-frame | ENST00000394818 | ENST00000310190 | INCENP | chr11 | 61908516 | + | CCS | chr11 | 66372810 | + |
| In-frame | ENST00000278849 | ENST00000533244 | INCENP | chr11 | 61908516 | + | CCS | chr11 | 66372810 | + |
| In-frame | ENST00000278849 | ENST00000310190 | INCENP | chr11 | 61908516 | + | CCS | chr11 | 66372810 | + |
| intron-3CDS | ENST00000531099 | ENST00000533244 | INCENP | chr11 | 61908516 | + | CCS | chr11 | 66372810 | + |
| intron-3CDS | ENST00000531099 | ENST00000310190 | INCENP | chr11 | 61908516 | + | CCS | chr11 | 66372810 | + |
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FusionProtFeatures for INCENP_CCS |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| INCENP | CCS |
| Component of the chromosomal passenger complex (CPC), acomplex that acts as a key regulator of mitosis. The CPC complexhas essential functions at the centromere in ensuring correctchromosome alignment and segregation and is required forchromatin-induced microtubule stabilization and spindle assembly.Acts as a scaffold regulating CPC localization and activity. TheC-terminus associates with AURKB or AURKC, the N-terminusassociated with BIRC5/survivin and CDCA8/borealin tethers the CPCto the inner centromere, and the microtubule binding activitywithin the central SAH domain directs AURKB/C toward substratesnear microtubules (PubMed:15316025, PubMed:12925766,PubMed:27332895). The flexibility of the SAH domain is proposed toallow AURKB/C to follow substrates on dynamic microtubules whileensuring CPC docking to static chromatin (By similarity).Activates AURKB and AURKC (PubMed:27332895). Required forlocalization of CBX5 to mitotic centromeres (PubMed:21346195).Controls the kinetochore localization of BUB1 (PubMed:16760428).{ECO:0000250|UniProtKB:P53352, ECO:0000269|PubMed:12925766,ECO:0000269|PubMed:15316025, ECO:0000269|PubMed:16760428,ECO:0000269|PubMed:21346195, ECO:0000269|PubMed:27332895}. | Delivers copper to copper zinc superoxide dismutase(SOD1). |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | INCENP | chr11:61908516 | chr11:66372810 | ENST00000278849 | + | 10 | 18 | 167_171 | 531 | 915 | Motif | PXVXL/I motif |
| Hgene | INCENP | chr11:61908516 | chr11:66372810 | ENST00000394818 | + | 10 | 19 | 167_171 | 531 | 919 | Motif | PXVXL/I motif |
| Hgene | INCENP | chr11:61908983 | chr11:66372810 | ENST00000394818 | + | 11 | 19 | 167_171 | 535 | 919 | Motif | PXVXL/I motif |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >INCENP | chr11:61908983 | chr11:66372810 | ENST00000278849 | + | 1 | 18 | 167_171 | -59 | 915 | Motif | PXVXL/I motif |
| Hgene | >INCENP | chr11:61908516 | chr11:66372810 | ENST00000278849 | + | 10 | 18 | 531_765 | 531 | 915 | Region | SAH |
| Hgene | >INCENP | chr11:61908516 | chr11:66372810 | ENST00000278849 | + | 10 | 18 | 826_900 | 531 | 915 | Region | IN box |
| Hgene | >INCENP | chr11:61908516 | chr11:66372810 | ENST00000394818 | + | 10 | 19 | 531_765 | 531 | 919 | Region | SAH |
| Hgene | >INCENP | chr11:61908516 | chr11:66372810 | ENST00000394818 | + | 10 | 19 | 826_900 | 531 | 919 | Region | IN box |
| Hgene | >INCENP | chr11:61908983 | chr11:66372810 | ENST00000278849 | + | 1 | 18 | 531_765 | -59 | 915 | Region | SAH |
| Hgene | >INCENP | chr11:61908983 | chr11:66372810 | ENST00000278849 | + | 1 | 18 | 826_900 | -59 | 915 | Region | IN box |
| Hgene | >INCENP | chr11:61908983 | chr11:66372810 | ENST00000394818 | + | 11 | 19 | 531_765 | 535 | 919 | Region | SAH |
| Hgene | >INCENP | chr11:61908983 | chr11:66372810 | ENST00000394818 | + | 11 | 19 | 826_900 | 535 | 919 | Region | IN box |
| Tgene | CCS | chr11:61908516 | chr11:66372810 | ENST00000533244 | + | 4 | 8 | 12_75 | 163 | 275 | Domain | HMA |
| Tgene | CCS | chr11:61908983 | chr11:66372810 | ENST00000533244 | + | 4 | 8 | 12_75 | 163 | 275 | Domain | HMA |
| Tgene | CCS | chr11:61908516 | chr11:66372810 | ENST00000533244 | + | 4 | 8 | 88_234 | 163 | 275 | Region | Note=Superoxide dismutase-like |
| Tgene | CCS | chr11:61908983 | chr11:66372810 | ENST00000533244 | + | 4 | 8 | 88_234 | 163 | 275 | Region | Note=Superoxide dismutase-like |
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FusionGeneSequence for INCENP_CCS |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_INCENP_ENST00000394818_chr11_61908983_+_CCS_ENST00000533244_chr11_66372810_+_647aa MGTTAPGPIHLLELCDQKLMEFLCNMDNKDLVWLEEIQEEAERMFTREFSKEPELMPKTPSQKNRRKKRRISYVQDENRDPIRRRLSRRK SRSSQLSSRRLRSKDSVEKLATVVGENGSVLRRVTRAAAAAAAATMALAAPSSPTPESPTMLTKKPEDNHTQCQLVPVVEIGISERQNAE QHVTQLMSTEPLPRTLSPTPASATAPTSQGIPTSDEESTPKKSKARILESITVSSLMATPQDPKGQGVGTGRSASKLRIAQVSPGPRDSP AFPDSPWRERVLAPILPDNFSTPTGSRTDSQSVRHSPIAPSSPSPQVLAQKYSLVAKQESVVRRASRRLAKKTAEEPAASGRIICHSYLE RLLNVEVPQKVGSEQKEPPEEAEPVAAAEPEVPENNGNNSWPHNDTEIANSTPNPKPAASSPETPSAGQQEAKTDQADGPREPPQSARRK RSYKQAVSELDEEQHLEDEELQPPRSKTPSSPCPASKVVRPLRTFLHTVQRNQMLMTPTSAPRSVMKSFIKRNTPLRMDPKCSFVHRGDL GNVRADADGRAIFRMEDEQLKVWDVIGRSLIIDEGEDDLGRGGHPLSKITGNSGERLACGIIARSAGLFQNPKQICSCDGLTIWEERGRP >In-frame_INCENP_ENST00000394818_chr11_61908983_+_CCS_ENST00000310190_chr11_66372810_+_647aa MGTTAPGPIHLLELCDQKLMEFLCNMDNKDLVWLEEIQEEAERMFTREFSKEPELMPKTPSQKNRRKKRRISYVQDENRDPIRRRLSRRK SRSSQLSSRRLRSKDSVEKLATVVGENGSVLRRVTRAAAAAAAATMALAAPSSPTPESPTMLTKKPEDNHTQCQLVPVVEIGISERQNAE QHVTQLMSTEPLPRTLSPTPASATAPTSQGIPTSDEESTPKKSKARILESITVSSLMATPQDPKGQGVGTGRSASKLRIAQVSPGPRDSP AFPDSPWRERVLAPILPDNFSTPTGSRTDSQSVRHSPIAPSSPSPQVLAQKYSLVAKQESVVRRASRRLAKKTAEEPAASGRIICHSYLE RLLNVEVPQKVGSEQKEPPEEAEPVAAAEPEVPENNGNNSWPHNDTEIANSTPNPKPAASSPETPSAGQQEAKTDQADGPREPPQSARRK RSYKQAVSELDEEQHLEDEELQPPRSKTPSSPCPASKVVRPLRTFLHTVQRNQMLMTPTSAPRSVMKSFIKRNTPLRMDPKCSFVHRGDL GNVRADADGRAIFRMEDEQLKVWDVIGRSLIIDEGEDDLGRGGHPLSKITGNSGERLACGIIARSAGLFQNPKQICSCDGLTIWEERGRP >In-frame_INCENP_ENST00000394818_chr11_61908516_+_CCS_ENST00000533244_chr11_66372810_+_643aa MGTTAPGPIHLLELCDQKLMEFLCNMDNKDLVWLEEIQEEAERMFTREFSKEPELMPKTPSQKNRRKKRRISYVQDENRDPIRRRLSRRK SRSSQLSSRRLRSKDSVEKLATVVGENGSVLRRVTRAAAAAAAATMALAAPSSPTPESPTMLTKKPEDNHTQCQLVPVVEIGISERQNAE QHVTQLMSTEPLPRTLSPTPASATAPTSQGIPTSDEESTPKKSKARILESITVSSLMATPQDPKGQGVGTGRSASKLRIAQVSPGPRDSP AFPDSPWRERVLAPILPDNFSTPTGSRTDSQSVRHSPIAPSSPSPQVLAQKYSLVAKQESVVRRASRRLAKKTAEEPAASGRIICHSYLE RLLNVEVPQKVGSEQKEPPEEAEPVAAAEPEVPENNGNNSWPHNDTEIANSTPNPKPAASSPETPSAGQQEAKTDQADGPREPPQSARRK RSYKQAVSELDEEQHLEDEELQPPRSKTPSSPCPASKVVRPLRTFLHTVQRNQMLMTPTSAPRSVMKSFIKRNTPLRMDPKHRGDLGNVR ADADGRAIFRMEDEQLKVWDVIGRSLIIDEGEDDLGRGGHPLSKITGNSGERLACGIIARSAGLFQNPKQICSCDGLTIWEERGRPIAGK >In-frame_INCENP_ENST00000394818_chr11_61908516_+_CCS_ENST00000310190_chr11_66372810_+_643aa MGTTAPGPIHLLELCDQKLMEFLCNMDNKDLVWLEEIQEEAERMFTREFSKEPELMPKTPSQKNRRKKRRISYVQDENRDPIRRRLSRRK SRSSQLSSRRLRSKDSVEKLATVVGENGSVLRRVTRAAAAAAAATMALAAPSSPTPESPTMLTKKPEDNHTQCQLVPVVEIGISERQNAE QHVTQLMSTEPLPRTLSPTPASATAPTSQGIPTSDEESTPKKSKARILESITVSSLMATPQDPKGQGVGTGRSASKLRIAQVSPGPRDSP AFPDSPWRERVLAPILPDNFSTPTGSRTDSQSVRHSPIAPSSPSPQVLAQKYSLVAKQESVVRRASRRLAKKTAEEPAASGRIICHSYLE RLLNVEVPQKVGSEQKEPPEEAEPVAAAEPEVPENNGNNSWPHNDTEIANSTPNPKPAASSPETPSAGQQEAKTDQADGPREPPQSARRK RSYKQAVSELDEEQHLEDEELQPPRSKTPSSPCPASKVVRPLRTFLHTVQRNQMLMTPTSAPRSVMKSFIKRNTPLRMDPKHRGDLGNVR ADADGRAIFRMEDEQLKVWDVIGRSLIIDEGEDDLGRGGHPLSKITGNSGERLACGIIARSAGLFQNPKQICSCDGLTIWEERGRPIAGK >In-frame_INCENP_ENST00000278849_chr11_61908516_+_CCS_ENST00000533244_chr11_66372810_+_643aa MGTTAPGPIHLLELCDQKLMEFLCNMDNKDLVWLEEIQEEAERMFTREFSKEPELMPKTPSQKNRRKKRRISYVQDENRDPIRRRLSRRK SRSSQLSSRRLRSKDSVEKLATVVGENGSVLRRVTRAAAAAAAATMALAAPSSPTPESPTMLTKKPEDNHTQCQLVPVVEIGISERQNAE QHVTQLMSTEPLPRTLSPTPASATAPTSQGIPTSDEESTPKKSKARILESITVSSLMATPQDPKGQGVGTGRSASKLRIAQVSPGPRDSP AFPDSPWRERVLAPILPDNFSTPTGSRTDSQSVRHSPIAPSSPSPQVLAQKYSLVAKQESVVRRASRRLAKKTAEEPAASGRIICHSYLE RLLNVEVPQKVGSEQKEPPEEAEPVAAAEPEVPENNGNNSWPHNDTEIANSTPNPKPAASSPETPSAGQQEAKTDQADGPREPPQSARRK RSYKQAVSELDEEQHLEDEELQPPRSKTPSSPCPASKVVRPLRTFLHTVQRNQMLMTPTSAPRSVMKSFIKRNTPLRMDPKHRGDLGNVR ADADGRAIFRMEDEQLKVWDVIGRSLIIDEGEDDLGRGGHPLSKITGNSGERLACGIIARSAGLFQNPKQICSCDGLTIWEERGRPIAGK >In-frame_INCENP_ENST00000278849_chr11_61908516_+_CCS_ENST00000310190_chr11_66372810_+_643aa MGTTAPGPIHLLELCDQKLMEFLCNMDNKDLVWLEEIQEEAERMFTREFSKEPELMPKTPSQKNRRKKRRISYVQDENRDPIRRRLSRRK SRSSQLSSRRLRSKDSVEKLATVVGENGSVLRRVTRAAAAAAAATMALAAPSSPTPESPTMLTKKPEDNHTQCQLVPVVEIGISERQNAE QHVTQLMSTEPLPRTLSPTPASATAPTSQGIPTSDEESTPKKSKARILESITVSSLMATPQDPKGQGVGTGRSASKLRIAQVSPGPRDSP AFPDSPWRERVLAPILPDNFSTPTGSRTDSQSVRHSPIAPSSPSPQVLAQKYSLVAKQESVVRRASRRLAKKTAEEPAASGRIICHSYLE RLLNVEVPQKVGSEQKEPPEEAEPVAAAEPEVPENNGNNSWPHNDTEIANSTPNPKPAASSPETPSAGQQEAKTDQADGPREPPQSARRK RSYKQAVSELDEEQHLEDEELQPPRSKTPSSPCPASKVVRPLRTFLHTVQRNQMLMTPTSAPRSVMKSFIKRNTPLRMDPKHRGDLGNVR ADADGRAIFRMEDEQLKVWDVIGRSLIIDEGEDDLGRGGHPLSKITGNSGERLACGIIARSAGLFQNPKQICSCDGLTIWEERGRPIAGK |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_INCENP_ENST00000394818_chr11_61908983_+_CCS_ENST00000533244_chr11_66372810_+_1941nt ATGGGGACGACGGCCCCAGGGCCCATTCACCTGCTGGAGCTATGTGACCAGAAGCTCATGGAGTTTCTCTGCAACATGGATAATAAGGAC TTGGTGTGGCTTGAGGAAATCCAAGAGGAGGCCGAGCGCATGTTCACCAGAGAATTCAGCAAAGAGCCAGAGCTGATGCCCAAAACACCT TCTCAGAAGAACCGACGGAAGAAGAGACGGATTTCTTATGTTCAGGATGAAAACAGAGATCCCATCAGGAGAAGGTTATCCCGCAGAAAG TCTCGGAGCAGCCAGCTGAGCTCCCGACGCCTCCGCAGCAAGGACAGTGTAGAGAAGCTGGCTACAGTGGTCGGGGAGAACGGCTCCGTC CTGCGGCGTGTGACCCGTGCTGCGGCTGCAGCTGCCGCGGCTACCATGGCATTGGCTGCACCTTCTTCACCCACCCCTGAGTCTCCCACG ATGCTGACTAAGAAGCCCGAGGATAACCACACCCAGTGCCAGCTGGTGCCTGTGGTGGAGATCGGCATCAGTGAGCGCCAGAATGCTGAG CAGCATGTCACCCAGCTCATGTCCACCGAGCCTCTGCCCCGCACTCTGTCCCCGACTCCAGCTTCAGCCACAGCTCCAACCTCCCAGGGC ATCCCGACATCAGATGAGGAATCAACACCTAAGAAGTCGAAGGCCAGGATACTGGAGTCCATCACAGTGAGCTCCCTGATGGCTACACCC CAGGACCCCAAGGGTCAAGGGGTCGGGACGGGGCGGTCTGCGTCTAAGCTCAGGATTGCGCAGGTCTCCCCTGGCCCACGGGACTCGCCA GCCTTTCCAGATTCTCCATGGCGGGAGCGGGTGCTGGCTCCCATCCTGCCGGATAACTTCTCCACGCCCACGGGCTCTCGCACGGACTCT CAATCGGTGCGGCACAGCCCGATCGCCCCGTCTTCCCCGAGTCCCCAAGTCTTAGCCCAGAAGTACTCTCTGGTGGCCAAACAGGAAAGT GTTGTCCGCAGGGCGAGCAGAAGGCTTGCCAAGAAGACTGCCGAAGAGCCAGCTGCCTCTGGCCGCATCATCTGTCACAGTTACCTGGAG AGGCTCCTGAATGTTGAGGTGCCCCAGAAAGTTGGTTCTGAGCAGAAGGAACCCCCCGAGGAGGCTGAGCCTGTGGCGGCAGCTGAGCCA GAGGTCCCTGAGAACAATGGAAATAACTCGTGGCCCCACAATGACACGGAGATTGCCAACAGCACACCCAACCCGAAGCCTGCAGCCAGC AGCCCGGAAACACCCTCTGCAGGGCAGCAAGAGGCCAAGACGGACCAAGCAGATGGACCCAGAGAGCCACCGCAGAGTGCCAGGAGGAAG CGCAGCTACAAGCAGGCCGTGAGTGAGCTGGACGAGGAGCAGCACCTGGAGGATGAGGAGCTGCAGCCCCCCAGGAGCAAGACCCCTTCC TCACCCTGCCCAGCCAGCAAGGTGGTACGGCCCCTCCGGACCTTTCTGCACACAGTGCAGAGGAACCAGATGCTCATGACCCCGACCTCA GCCCCACGCAGCGTCATGAAGTCCTTTATTAAGCGCAACACTCCCCTGCGCATGGACCCCAAGTGCAGCTTCGTCCACCGCGGAGACCTG GGCAATGTCCGTGCTGATGCTGACGGCCGCGCCATCTTCAGAATGGAGGATGAGCAGCTGAAGGTGTGGGATGTGATTGGCCGCAGCCTG ATTATTGATGAGGGAGAAGATGACCTGGGCCGGGGAGGCCATCCCTTATCCAAGATCACAGGGAACTCCGGGGAGAGGTTGGCCTGTGGC ATCATTGCACGCTCCGCTGGCCTTTTCCAGAACCCCAAGCAGATCTGCTCTTGCGATGGCCTCACCATCTGGGAGGAGCGAGGCCGGCCC >In-frame_INCENP_ENST00000394818_chr11_61908983_+_CCS_ENST00000310190_chr11_66372810_+_1941nt ATGGGGACGACGGCCCCAGGGCCCATTCACCTGCTGGAGCTATGTGACCAGAAGCTCATGGAGTTTCTCTGCAACATGGATAATAAGGAC TTGGTGTGGCTTGAGGAAATCCAAGAGGAGGCCGAGCGCATGTTCACCAGAGAATTCAGCAAAGAGCCAGAGCTGATGCCCAAAACACCT TCTCAGAAGAACCGACGGAAGAAGAGACGGATTTCTTATGTTCAGGATGAAAACAGAGATCCCATCAGGAGAAGGTTATCCCGCAGAAAG TCTCGGAGCAGCCAGCTGAGCTCCCGACGCCTCCGCAGCAAGGACAGTGTAGAGAAGCTGGCTACAGTGGTCGGGGAGAACGGCTCCGTC CTGCGGCGTGTGACCCGTGCTGCGGCTGCAGCTGCCGCGGCTACCATGGCATTGGCTGCACCTTCTTCACCCACCCCTGAGTCTCCCACG ATGCTGACTAAGAAGCCCGAGGATAACCACACCCAGTGCCAGCTGGTGCCTGTGGTGGAGATCGGCATCAGTGAGCGCCAGAATGCTGAG CAGCATGTCACCCAGCTCATGTCCACCGAGCCTCTGCCCCGCACTCTGTCCCCGACTCCAGCTTCAGCCACAGCTCCAACCTCCCAGGGC ATCCCGACATCAGATGAGGAATCAACACCTAAGAAGTCGAAGGCCAGGATACTGGAGTCCATCACAGTGAGCTCCCTGATGGCTACACCC CAGGACCCCAAGGGTCAAGGGGTCGGGACGGGGCGGTCTGCGTCTAAGCTCAGGATTGCGCAGGTCTCCCCTGGCCCACGGGACTCGCCA GCCTTTCCAGATTCTCCATGGCGGGAGCGGGTGCTGGCTCCCATCCTGCCGGATAACTTCTCCACGCCCACGGGCTCTCGCACGGACTCT CAATCGGTGCGGCACAGCCCGATCGCCCCGTCTTCCCCGAGTCCCCAAGTCTTAGCCCAGAAGTACTCTCTGGTGGCCAAACAGGAAAGT GTTGTCCGCAGGGCGAGCAGAAGGCTTGCCAAGAAGACTGCCGAAGAGCCAGCTGCCTCTGGCCGCATCATCTGTCACAGTTACCTGGAG AGGCTCCTGAATGTTGAGGTGCCCCAGAAAGTTGGTTCTGAGCAGAAGGAACCCCCCGAGGAGGCTGAGCCTGTGGCGGCAGCTGAGCCA GAGGTCCCTGAGAACAATGGAAATAACTCGTGGCCCCACAATGACACGGAGATTGCCAACAGCACACCCAACCCGAAGCCTGCAGCCAGC AGCCCGGAAACACCCTCTGCAGGGCAGCAAGAGGCCAAGACGGACCAAGCAGATGGACCCAGAGAGCCACCGCAGAGTGCCAGGAGGAAG CGCAGCTACAAGCAGGCCGTGAGTGAGCTGGACGAGGAGCAGCACCTGGAGGATGAGGAGCTGCAGCCCCCCAGGAGCAAGACCCCTTCC TCACCCTGCCCAGCCAGCAAGGTGGTACGGCCCCTCCGGACCTTTCTGCACACAGTGCAGAGGAACCAGATGCTCATGACCCCGACCTCA GCCCCACGCAGCGTCATGAAGTCCTTTATTAAGCGCAACACTCCCCTGCGCATGGACCCCAAGTGCAGCTTCGTCCACCGCGGAGACCTG GGCAATGTCCGTGCTGATGCTGACGGCCGCGCCATCTTCAGAATGGAGGATGAGCAGCTGAAGGTGTGGGATGTGATTGGCCGCAGCCTG ATTATTGATGAGGGAGAAGATGACCTGGGCCGGGGAGGCCATCCCTTATCCAAGATCACAGGGAACTCCGGGGAGAGGTTGGCCTGTGGC ATCATTGCACGCTCCGCTGGCCTTTTCCAGAACCCCAAGCAGATCTGCTCTTGCGATGGCCTCACCATCTGGGAGGAGCGAGGCCGGCCC >In-frame_INCENP_ENST00000394818_chr11_61908516_+_CCS_ENST00000533244_chr11_66372810_+_1929nt ATGGGGACGACGGCCCCAGGGCCCATTCACCTGCTGGAGCTATGTGACCAGAAGCTCATGGAGTTTCTCTGCAACATGGATAATAAGGAC TTGGTGTGGCTTGAGGAAATCCAAGAGGAGGCCGAGCGCATGTTCACCAGAGAATTCAGCAAAGAGCCAGAGCTGATGCCCAAAACACCT TCTCAGAAGAACCGACGGAAGAAGAGACGGATTTCTTATGTTCAGGATGAAAACAGAGATCCCATCAGGAGAAGGTTATCCCGCAGAAAG TCTCGGAGCAGCCAGCTGAGCTCCCGACGCCTCCGCAGCAAGGACAGTGTAGAGAAGCTGGCTACAGTGGTCGGGGAGAACGGCTCCGTC CTGCGGCGTGTGACCCGTGCTGCGGCTGCAGCTGCCGCGGCTACCATGGCATTGGCTGCACCTTCTTCACCCACCCCTGAGTCTCCCACG ATGCTGACTAAGAAGCCCGAGGATAACCACACCCAGTGCCAGCTGGTGCCTGTGGTGGAGATCGGCATCAGTGAGCGCCAGAATGCTGAG CAGCATGTCACCCAGCTCATGTCCACCGAGCCTCTGCCCCGCACTCTGTCCCCGACTCCAGCTTCAGCCACAGCTCCAACCTCCCAGGGC ATCCCGACATCAGATGAGGAATCAACACCTAAGAAGTCGAAGGCCAGGATACTGGAGTCCATCACAGTGAGCTCCCTGATGGCTACACCC CAGGACCCCAAGGGTCAAGGGGTCGGGACGGGGCGGTCTGCGTCTAAGCTCAGGATTGCGCAGGTCTCCCCTGGCCCACGGGACTCGCCA GCCTTTCCAGATTCTCCATGGCGGGAGCGGGTGCTGGCTCCCATCCTGCCGGATAACTTCTCCACGCCCACGGGCTCTCGCACGGACTCT CAATCGGTGCGGCACAGCCCGATCGCCCCGTCTTCCCCGAGTCCCCAAGTCTTAGCCCAGAAGTACTCTCTGGTGGCCAAACAGGAAAGT GTTGTCCGCAGGGCGAGCAGAAGGCTTGCCAAGAAGACTGCCGAAGAGCCAGCTGCCTCTGGCCGCATCATCTGTCACAGTTACCTGGAG AGGCTCCTGAATGTTGAGGTGCCCCAGAAAGTTGGTTCTGAGCAGAAGGAACCCCCCGAGGAGGCTGAGCCTGTGGCGGCAGCTGAGCCA GAGGTCCCTGAGAACAATGGAAATAACTCGTGGCCCCACAATGACACGGAGATTGCCAACAGCACACCCAACCCGAAGCCTGCAGCCAGC AGCCCGGAAACACCCTCTGCAGGGCAGCAAGAGGCCAAGACGGACCAAGCAGATGGACCCAGAGAGCCACCGCAGAGTGCCAGGAGGAAG CGCAGCTACAAGCAGGCCGTGAGTGAGCTGGACGAGGAGCAGCACCTGGAGGATGAGGAGCTGCAGCCCCCCAGGAGCAAGACCCCTTCC TCACCCTGCCCAGCCAGCAAGGTGGTACGGCCCCTCCGGACCTTTCTGCACACAGTGCAGAGGAACCAGATGCTCATGACCCCGACCTCA GCCCCACGCAGCGTCATGAAGTCCTTTATTAAGCGCAACACTCCCCTGCGCATGGACCCCAAGCACCGCGGAGACCTGGGCAATGTCCGT GCTGATGCTGACGGCCGCGCCATCTTCAGAATGGAGGATGAGCAGCTGAAGGTGTGGGATGTGATTGGCCGCAGCCTGATTATTGATGAG GGAGAAGATGACCTGGGCCGGGGAGGCCATCCCTTATCCAAGATCACAGGGAACTCCGGGGAGAGGTTGGCCTGTGGCATCATTGCACGC TCCGCTGGCCTTTTCCAGAACCCCAAGCAGATCTGCTCTTGCGATGGCCTCACCATCTGGGAGGAGCGAGGCCGGCCCATCGCTGGCAAG >In-frame_INCENP_ENST00000394818_chr11_61908516_+_CCS_ENST00000310190_chr11_66372810_+_1929nt ATGGGGACGACGGCCCCAGGGCCCATTCACCTGCTGGAGCTATGTGACCAGAAGCTCATGGAGTTTCTCTGCAACATGGATAATAAGGAC TTGGTGTGGCTTGAGGAAATCCAAGAGGAGGCCGAGCGCATGTTCACCAGAGAATTCAGCAAAGAGCCAGAGCTGATGCCCAAAACACCT TCTCAGAAGAACCGACGGAAGAAGAGACGGATTTCTTATGTTCAGGATGAAAACAGAGATCCCATCAGGAGAAGGTTATCCCGCAGAAAG TCTCGGAGCAGCCAGCTGAGCTCCCGACGCCTCCGCAGCAAGGACAGTGTAGAGAAGCTGGCTACAGTGGTCGGGGAGAACGGCTCCGTC CTGCGGCGTGTGACCCGTGCTGCGGCTGCAGCTGCCGCGGCTACCATGGCATTGGCTGCACCTTCTTCACCCACCCCTGAGTCTCCCACG ATGCTGACTAAGAAGCCCGAGGATAACCACACCCAGTGCCAGCTGGTGCCTGTGGTGGAGATCGGCATCAGTGAGCGCCAGAATGCTGAG CAGCATGTCACCCAGCTCATGTCCACCGAGCCTCTGCCCCGCACTCTGTCCCCGACTCCAGCTTCAGCCACAGCTCCAACCTCCCAGGGC ATCCCGACATCAGATGAGGAATCAACACCTAAGAAGTCGAAGGCCAGGATACTGGAGTCCATCACAGTGAGCTCCCTGATGGCTACACCC CAGGACCCCAAGGGTCAAGGGGTCGGGACGGGGCGGTCTGCGTCTAAGCTCAGGATTGCGCAGGTCTCCCCTGGCCCACGGGACTCGCCA GCCTTTCCAGATTCTCCATGGCGGGAGCGGGTGCTGGCTCCCATCCTGCCGGATAACTTCTCCACGCCCACGGGCTCTCGCACGGACTCT CAATCGGTGCGGCACAGCCCGATCGCCCCGTCTTCCCCGAGTCCCCAAGTCTTAGCCCAGAAGTACTCTCTGGTGGCCAAACAGGAAAGT GTTGTCCGCAGGGCGAGCAGAAGGCTTGCCAAGAAGACTGCCGAAGAGCCAGCTGCCTCTGGCCGCATCATCTGTCACAGTTACCTGGAG AGGCTCCTGAATGTTGAGGTGCCCCAGAAAGTTGGTTCTGAGCAGAAGGAACCCCCCGAGGAGGCTGAGCCTGTGGCGGCAGCTGAGCCA GAGGTCCCTGAGAACAATGGAAATAACTCGTGGCCCCACAATGACACGGAGATTGCCAACAGCACACCCAACCCGAAGCCTGCAGCCAGC AGCCCGGAAACACCCTCTGCAGGGCAGCAAGAGGCCAAGACGGACCAAGCAGATGGACCCAGAGAGCCACCGCAGAGTGCCAGGAGGAAG CGCAGCTACAAGCAGGCCGTGAGTGAGCTGGACGAGGAGCAGCACCTGGAGGATGAGGAGCTGCAGCCCCCCAGGAGCAAGACCCCTTCC TCACCCTGCCCAGCCAGCAAGGTGGTACGGCCCCTCCGGACCTTTCTGCACACAGTGCAGAGGAACCAGATGCTCATGACCCCGACCTCA GCCCCACGCAGCGTCATGAAGTCCTTTATTAAGCGCAACACTCCCCTGCGCATGGACCCCAAGCACCGCGGAGACCTGGGCAATGTCCGT GCTGATGCTGACGGCCGCGCCATCTTCAGAATGGAGGATGAGCAGCTGAAGGTGTGGGATGTGATTGGCCGCAGCCTGATTATTGATGAG GGAGAAGATGACCTGGGCCGGGGAGGCCATCCCTTATCCAAGATCACAGGGAACTCCGGGGAGAGGTTGGCCTGTGGCATCATTGCACGC TCCGCTGGCCTTTTCCAGAACCCCAAGCAGATCTGCTCTTGCGATGGCCTCACCATCTGGGAGGAGCGAGGCCGGCCCATCGCTGGCAAG >In-frame_INCENP_ENST00000278849_chr11_61908516_+_CCS_ENST00000533244_chr11_66372810_+_1929nt ATGGGGACGACGGCCCCAGGGCCCATTCACCTGCTGGAGCTATGTGACCAGAAGCTCATGGAGTTTCTCTGCAACATGGATAATAAGGAC TTGGTGTGGCTTGAGGAAATCCAAGAGGAGGCCGAGCGCATGTTCACCAGAGAATTCAGCAAAGAGCCAGAGCTGATGCCCAAAACACCT TCTCAGAAGAACCGACGGAAGAAGAGACGGATTTCTTATGTTCAGGATGAAAACAGAGATCCCATCAGGAGAAGGTTATCCCGCAGAAAG TCTCGGAGCAGCCAGCTGAGCTCCCGACGCCTCCGCAGCAAGGACAGTGTAGAGAAGCTGGCTACAGTGGTCGGGGAGAACGGCTCCGTC CTGCGGCGTGTGACCCGTGCTGCGGCTGCAGCTGCCGCGGCTACCATGGCATTGGCTGCACCTTCTTCACCCACCCCTGAGTCTCCCACG ATGCTGACTAAGAAGCCCGAGGATAACCACACCCAGTGCCAGCTGGTGCCTGTGGTGGAGATCGGCATCAGTGAGCGCCAGAATGCTGAG CAGCATGTCACCCAGCTCATGTCCACCGAGCCTCTGCCCCGCACTCTGTCCCCGACTCCAGCTTCAGCCACAGCTCCAACCTCCCAGGGC ATCCCGACATCAGATGAGGAATCAACACCTAAGAAGTCGAAGGCCAGGATACTGGAGTCCATCACAGTGAGCTCCCTGATGGCTACACCC CAGGACCCCAAGGGTCAAGGGGTCGGGACGGGGCGGTCTGCGTCTAAGCTCAGGATTGCGCAGGTCTCCCCTGGCCCACGGGACTCGCCA GCCTTTCCAGATTCTCCATGGCGGGAGCGGGTGCTGGCTCCCATCCTGCCGGATAACTTCTCCACGCCCACGGGCTCTCGCACGGACTCT CAATCGGTGCGGCACAGCCCGATCGCCCCGTCTTCCCCGAGTCCCCAAGTCTTAGCCCAGAAGTACTCTCTGGTGGCCAAACAGGAAAGT GTTGTCCGCAGGGCGAGCAGAAGGCTTGCCAAGAAGACTGCCGAAGAGCCAGCTGCCTCTGGCCGCATCATCTGTCACAGTTACCTGGAG AGGCTCCTGAATGTTGAGGTGCCCCAGAAAGTTGGTTCTGAGCAGAAGGAACCCCCCGAGGAGGCTGAGCCTGTGGCGGCAGCTGAGCCA GAGGTCCCTGAGAACAATGGAAATAACTCGTGGCCCCACAATGACACGGAGATTGCCAACAGCACACCCAACCCGAAGCCTGCAGCCAGC AGCCCGGAAACACCCTCTGCAGGGCAGCAAGAGGCCAAGACGGACCAAGCAGATGGACCCAGAGAGCCACCGCAGAGTGCCAGGAGGAAG CGCAGCTACAAGCAGGCCGTGAGTGAGCTGGACGAGGAGCAGCACCTGGAGGATGAGGAGCTGCAGCCCCCCAGGAGCAAGACCCCTTCC TCACCCTGCCCAGCCAGCAAGGTGGTACGGCCCCTCCGGACCTTTCTGCACACAGTGCAGAGGAACCAGATGCTCATGACCCCGACCTCA GCCCCACGCAGCGTCATGAAGTCCTTTATTAAGCGCAACACTCCCCTGCGCATGGACCCCAAGCACCGCGGAGACCTGGGCAATGTCCGT GCTGATGCTGACGGCCGCGCCATCTTCAGAATGGAGGATGAGCAGCTGAAGGTGTGGGATGTGATTGGCCGCAGCCTGATTATTGATGAG GGAGAAGATGACCTGGGCCGGGGAGGCCATCCCTTATCCAAGATCACAGGGAACTCCGGGGAGAGGTTGGCCTGTGGCATCATTGCACGC TCCGCTGGCCTTTTCCAGAACCCCAAGCAGATCTGCTCTTGCGATGGCCTCACCATCTGGGAGGAGCGAGGCCGGCCCATCGCTGGCAAG >In-frame_INCENP_ENST00000278849_chr11_61908516_+_CCS_ENST00000310190_chr11_66372810_+_1929nt ATGGGGACGACGGCCCCAGGGCCCATTCACCTGCTGGAGCTATGTGACCAGAAGCTCATGGAGTTTCTCTGCAACATGGATAATAAGGAC TTGGTGTGGCTTGAGGAAATCCAAGAGGAGGCCGAGCGCATGTTCACCAGAGAATTCAGCAAAGAGCCAGAGCTGATGCCCAAAACACCT TCTCAGAAGAACCGACGGAAGAAGAGACGGATTTCTTATGTTCAGGATGAAAACAGAGATCCCATCAGGAGAAGGTTATCCCGCAGAAAG TCTCGGAGCAGCCAGCTGAGCTCCCGACGCCTCCGCAGCAAGGACAGTGTAGAGAAGCTGGCTACAGTGGTCGGGGAGAACGGCTCCGTC CTGCGGCGTGTGACCCGTGCTGCGGCTGCAGCTGCCGCGGCTACCATGGCATTGGCTGCACCTTCTTCACCCACCCCTGAGTCTCCCACG ATGCTGACTAAGAAGCCCGAGGATAACCACACCCAGTGCCAGCTGGTGCCTGTGGTGGAGATCGGCATCAGTGAGCGCCAGAATGCTGAG CAGCATGTCACCCAGCTCATGTCCACCGAGCCTCTGCCCCGCACTCTGTCCCCGACTCCAGCTTCAGCCACAGCTCCAACCTCCCAGGGC ATCCCGACATCAGATGAGGAATCAACACCTAAGAAGTCGAAGGCCAGGATACTGGAGTCCATCACAGTGAGCTCCCTGATGGCTACACCC CAGGACCCCAAGGGTCAAGGGGTCGGGACGGGGCGGTCTGCGTCTAAGCTCAGGATTGCGCAGGTCTCCCCTGGCCCACGGGACTCGCCA GCCTTTCCAGATTCTCCATGGCGGGAGCGGGTGCTGGCTCCCATCCTGCCGGATAACTTCTCCACGCCCACGGGCTCTCGCACGGACTCT CAATCGGTGCGGCACAGCCCGATCGCCCCGTCTTCCCCGAGTCCCCAAGTCTTAGCCCAGAAGTACTCTCTGGTGGCCAAACAGGAAAGT GTTGTCCGCAGGGCGAGCAGAAGGCTTGCCAAGAAGACTGCCGAAGAGCCAGCTGCCTCTGGCCGCATCATCTGTCACAGTTACCTGGAG AGGCTCCTGAATGTTGAGGTGCCCCAGAAAGTTGGTTCTGAGCAGAAGGAACCCCCCGAGGAGGCTGAGCCTGTGGCGGCAGCTGAGCCA GAGGTCCCTGAGAACAATGGAAATAACTCGTGGCCCCACAATGACACGGAGATTGCCAACAGCACACCCAACCCGAAGCCTGCAGCCAGC AGCCCGGAAACACCCTCTGCAGGGCAGCAAGAGGCCAAGACGGACCAAGCAGATGGACCCAGAGAGCCACCGCAGAGTGCCAGGAGGAAG CGCAGCTACAAGCAGGCCGTGAGTGAGCTGGACGAGGAGCAGCACCTGGAGGATGAGGAGCTGCAGCCCCCCAGGAGCAAGACCCCTTCC TCACCCTGCCCAGCCAGCAAGGTGGTACGGCCCCTCCGGACCTTTCTGCACACAGTGCAGAGGAACCAGATGCTCATGACCCCGACCTCA GCCCCACGCAGCGTCATGAAGTCCTTTATTAAGCGCAACACTCCCCTGCGCATGGACCCCAAGCACCGCGGAGACCTGGGCAATGTCCGT GCTGATGCTGACGGCCGCGCCATCTTCAGAATGGAGGATGAGCAGCTGAAGGTGTGGGATGTGATTGGCCGCAGCCTGATTATTGATGAG GGAGAAGATGACCTGGGCCGGGGAGGCCATCCCTTATCCAAGATCACAGGGAACTCCGGGGAGAGGTTGGCCTGTGGCATCATTGCACGC TCCGCTGGCCTTTTCCAGAACCCCAAGCAGATCTGCTCTTGCGATGGCCTCACCATCTGGGAGGAGCGAGGCCGGCCCATCGCTGGCAAG |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_INCENP_ENST00000394818_chr11_61908983_+_CCS_ENST00000533244_chr11_66372810_+_2307nt CTTGCCGAGGATTGGCTGAGCCTTCAGTTTTGAAAATCATAGTTTTCGCCCGCGCTGCGCCGCCTGGTTGCTCCTCCCGTGCGGTGAGTC CCGAAGGCCCGGAGCCAAGTGGGTCTGGGCAAGCGGGGCCTTACCTAGGGATACCACCGGACTTGGATCGGAGCAGCCTTCAGGGGACGT GGCGCAGTCGAACAGAGCCACCATGGGGACGACGGCCCCAGGGCCCATTCACCTGCTGGAGCTATGTGACCAGAAGCTCATGGAGTTTCT CTGCAACATGGATAATAAGGACTTGGTGTGGCTTGAGGAAATCCAAGAGGAGGCCGAGCGCATGTTCACCAGAGAATTCAGCAAAGAGCC AGAGCTGATGCCCAAAACACCTTCTCAGAAGAACCGACGGAAGAAGAGACGGATTTCTTATGTTCAGGATGAAAACAGAGATCCCATCAG GAGAAGGTTATCCCGCAGAAAGTCTCGGAGCAGCCAGCTGAGCTCCCGACGCCTCCGCAGCAAGGACAGTGTAGAGAAGCTGGCTACAGT GGTCGGGGAGAACGGCTCCGTCCTGCGGCGTGTGACCCGTGCTGCGGCTGCAGCTGCCGCGGCTACCATGGCATTGGCTGCACCTTCTTC ACCCACCCCTGAGTCTCCCACGATGCTGACTAAGAAGCCCGAGGATAACCACACCCAGTGCCAGCTGGTGCCTGTGGTGGAGATCGGCAT CAGTGAGCGCCAGAATGCTGAGCAGCATGTCACCCAGCTCATGTCCACCGAGCCTCTGCCCCGCACTCTGTCCCCGACTCCAGCTTCAGC CACAGCTCCAACCTCCCAGGGCATCCCGACATCAGATGAGGAATCAACACCTAAGAAGTCGAAGGCCAGGATACTGGAGTCCATCACAGT GAGCTCCCTGATGGCTACACCCCAGGACCCCAAGGGTCAAGGGGTCGGGACGGGGCGGTCTGCGTCTAAGCTCAGGATTGCGCAGGTCTC CCCTGGCCCACGGGACTCGCCAGCCTTTCCAGATTCTCCATGGCGGGAGCGGGTGCTGGCTCCCATCCTGCCGGATAACTTCTCCACGCC CACGGGCTCTCGCACGGACTCTCAATCGGTGCGGCACAGCCCGATCGCCCCGTCTTCCCCGAGTCCCCAAGTCTTAGCCCAGAAGTACTC TCTGGTGGCCAAACAGGAAAGTGTTGTCCGCAGGGCGAGCAGAAGGCTTGCCAAGAAGACTGCCGAAGAGCCAGCTGCCTCTGGCCGCAT CATCTGTCACAGTTACCTGGAGAGGCTCCTGAATGTTGAGGTGCCCCAGAAAGTTGGTTCTGAGCAGAAGGAACCCCCCGAGGAGGCTGA GCCTGTGGCGGCAGCTGAGCCAGAGGTCCCTGAGAACAATGGAAATAACTCGTGGCCCCACAATGACACGGAGATTGCCAACAGCACACC CAACCCGAAGCCTGCAGCCAGCAGCCCGGAAACACCCTCTGCAGGGCAGCAAGAGGCCAAGACGGACCAAGCAGATGGACCCAGAGAGCC ACCGCAGAGTGCCAGGAGGAAGCGCAGCTACAAGCAGGCCGTGAGTGAGCTGGACGAGGAGCAGCACCTGGAGGATGAGGAGCTGCAGCC CCCCAGGAGCAAGACCCCTTCCTCACCCTGCCCAGCCAGCAAGGTGGTACGGCCCCTCCGGACCTTTCTGCACACAGTGCAGAGGAACCA GATGCTCATGACCCCGACCTCAGCCCCACGCAGCGTCATGAAGTCCTTTATTAAGCGCAACACTCCCCTGCGCATGGACCCCAAGTGCAG CTTCGTCCACCGCGGAGACCTGGGCAATGTCCGTGCTGATGCTGACGGCCGCGCCATCTTCAGAATGGAGGATGAGCAGCTGAAGGTGTG GGATGTGATTGGCCGCAGCCTGATTATTGATGAGGGAGAAGATGACCTGGGCCGGGGAGGCCATCCCTTATCCAAGATCACAGGGAACTC CGGGGAGAGGTTGGCCTGTGGCATCATTGCACGCTCCGCTGGCCTTTTCCAGAACCCCAAGCAGATCTGCTCTTGCGATGGCCTCACCAT CTGGGAGGAGCGAGGCCGGCCCATCGCTGGCAAGGGCCGAAAGGAGTCAGCGCAGCCCCCTGCCCACCTTTGAGCAGGACCTCACCTTGG CTCTGTTGCTGTCCTCCAGGGCGAGCACTTTCCACTTCCAGAGGGGGCCAGAGGGACTTTGCCTGCCCAGTCTTTGGAGAGCTCAGTACA >In-frame_INCENP_ENST00000394818_chr11_61908983_+_CCS_ENST00000310190_chr11_66372810_+_2207nt CTTGCCGAGGATTGGCTGAGCCTTCAGTTTTGAAAATCATAGTTTTCGCCCGCGCTGCGCCGCCTGGTTGCTCCTCCCGTGCGGTGAGTC CCGAAGGCCCGGAGCCAAGTGGGTCTGGGCAAGCGGGGCCTTACCTAGGGATACCACCGGACTTGGATCGGAGCAGCCTTCAGGGGACGT GGCGCAGTCGAACAGAGCCACCATGGGGACGACGGCCCCAGGGCCCATTCACCTGCTGGAGCTATGTGACCAGAAGCTCATGGAGTTTCT CTGCAACATGGATAATAAGGACTTGGTGTGGCTTGAGGAAATCCAAGAGGAGGCCGAGCGCATGTTCACCAGAGAATTCAGCAAAGAGCC AGAGCTGATGCCCAAAACACCTTCTCAGAAGAACCGACGGAAGAAGAGACGGATTTCTTATGTTCAGGATGAAAACAGAGATCCCATCAG GAGAAGGTTATCCCGCAGAAAGTCTCGGAGCAGCCAGCTGAGCTCCCGACGCCTCCGCAGCAAGGACAGTGTAGAGAAGCTGGCTACAGT GGTCGGGGAGAACGGCTCCGTCCTGCGGCGTGTGACCCGTGCTGCGGCTGCAGCTGCCGCGGCTACCATGGCATTGGCTGCACCTTCTTC ACCCACCCCTGAGTCTCCCACGATGCTGACTAAGAAGCCCGAGGATAACCACACCCAGTGCCAGCTGGTGCCTGTGGTGGAGATCGGCAT CAGTGAGCGCCAGAATGCTGAGCAGCATGTCACCCAGCTCATGTCCACCGAGCCTCTGCCCCGCACTCTGTCCCCGACTCCAGCTTCAGC CACAGCTCCAACCTCCCAGGGCATCCCGACATCAGATGAGGAATCAACACCTAAGAAGTCGAAGGCCAGGATACTGGAGTCCATCACAGT GAGCTCCCTGATGGCTACACCCCAGGACCCCAAGGGTCAAGGGGTCGGGACGGGGCGGTCTGCGTCTAAGCTCAGGATTGCGCAGGTCTC CCCTGGCCCACGGGACTCGCCAGCCTTTCCAGATTCTCCATGGCGGGAGCGGGTGCTGGCTCCCATCCTGCCGGATAACTTCTCCACGCC CACGGGCTCTCGCACGGACTCTCAATCGGTGCGGCACAGCCCGATCGCCCCGTCTTCCCCGAGTCCCCAAGTCTTAGCCCAGAAGTACTC TCTGGTGGCCAAACAGGAAAGTGTTGTCCGCAGGGCGAGCAGAAGGCTTGCCAAGAAGACTGCCGAAGAGCCAGCTGCCTCTGGCCGCAT CATCTGTCACAGTTACCTGGAGAGGCTCCTGAATGTTGAGGTGCCCCAGAAAGTTGGTTCTGAGCAGAAGGAACCCCCCGAGGAGGCTGA GCCTGTGGCGGCAGCTGAGCCAGAGGTCCCTGAGAACAATGGAAATAACTCGTGGCCCCACAATGACACGGAGATTGCCAACAGCACACC CAACCCGAAGCCTGCAGCCAGCAGCCCGGAAACACCCTCTGCAGGGCAGCAAGAGGCCAAGACGGACCAAGCAGATGGACCCAGAGAGCC ACCGCAGAGTGCCAGGAGGAAGCGCAGCTACAAGCAGGCCGTGAGTGAGCTGGACGAGGAGCAGCACCTGGAGGATGAGGAGCTGCAGCC CCCCAGGAGCAAGACCCCTTCCTCACCCTGCCCAGCCAGCAAGGTGGTACGGCCCCTCCGGACCTTTCTGCACACAGTGCAGAGGAACCA GATGCTCATGACCCCGACCTCAGCCCCACGCAGCGTCATGAAGTCCTTTATTAAGCGCAACACTCCCCTGCGCATGGACCCCAAGTGCAG CTTCGTCCACCGCGGAGACCTGGGCAATGTCCGTGCTGATGCTGACGGCCGCGCCATCTTCAGAATGGAGGATGAGCAGCTGAAGGTGTG GGATGTGATTGGCCGCAGCCTGATTATTGATGAGGGAGAAGATGACCTGGGCCGGGGAGGCCATCCCTTATCCAAGATCACAGGGAACTC CGGGGAGAGGTTGGCCTGTGGCATCATTGCACGCTCCGCTGGCCTTTTCCAGAACCCCAAGCAGATCTGCTCTTGCGATGGCCTCACCAT CTGGGAGGAGCGAGGCCGGCCCATCGCTGGCAAGGGCCGAAAGGAGTCAGCGCAGCCCCCTGCCCACCTTTGAGCAGGACCTCACCTTGG >In-frame_INCENP_ENST00000394818_chr11_61908516_+_CCS_ENST00000533244_chr11_66372810_+_2295nt CTTGCCGAGGATTGGCTGAGCCTTCAGTTTTGAAAATCATAGTTTTCGCCCGCGCTGCGCCGCCTGGTTGCTCCTCCCGTGCGGTGAGTC CCGAAGGCCCGGAGCCAAGTGGGTCTGGGCAAGCGGGGCCTTACCTAGGGATACCACCGGACTTGGATCGGAGCAGCCTTCAGGGGACGT GGCGCAGTCGAACAGAGCCACCATGGGGACGACGGCCCCAGGGCCCATTCACCTGCTGGAGCTATGTGACCAGAAGCTCATGGAGTTTCT CTGCAACATGGATAATAAGGACTTGGTGTGGCTTGAGGAAATCCAAGAGGAGGCCGAGCGCATGTTCACCAGAGAATTCAGCAAAGAGCC AGAGCTGATGCCCAAAACACCTTCTCAGAAGAACCGACGGAAGAAGAGACGGATTTCTTATGTTCAGGATGAAAACAGAGATCCCATCAG GAGAAGGTTATCCCGCAGAAAGTCTCGGAGCAGCCAGCTGAGCTCCCGACGCCTCCGCAGCAAGGACAGTGTAGAGAAGCTGGCTACAGT GGTCGGGGAGAACGGCTCCGTCCTGCGGCGTGTGACCCGTGCTGCGGCTGCAGCTGCCGCGGCTACCATGGCATTGGCTGCACCTTCTTC ACCCACCCCTGAGTCTCCCACGATGCTGACTAAGAAGCCCGAGGATAACCACACCCAGTGCCAGCTGGTGCCTGTGGTGGAGATCGGCAT CAGTGAGCGCCAGAATGCTGAGCAGCATGTCACCCAGCTCATGTCCACCGAGCCTCTGCCCCGCACTCTGTCCCCGACTCCAGCTTCAGC CACAGCTCCAACCTCCCAGGGCATCCCGACATCAGATGAGGAATCAACACCTAAGAAGTCGAAGGCCAGGATACTGGAGTCCATCACAGT GAGCTCCCTGATGGCTACACCCCAGGACCCCAAGGGTCAAGGGGTCGGGACGGGGCGGTCTGCGTCTAAGCTCAGGATTGCGCAGGTCTC CCCTGGCCCACGGGACTCGCCAGCCTTTCCAGATTCTCCATGGCGGGAGCGGGTGCTGGCTCCCATCCTGCCGGATAACTTCTCCACGCC CACGGGCTCTCGCACGGACTCTCAATCGGTGCGGCACAGCCCGATCGCCCCGTCTTCCCCGAGTCCCCAAGTCTTAGCCCAGAAGTACTC TCTGGTGGCCAAACAGGAAAGTGTTGTCCGCAGGGCGAGCAGAAGGCTTGCCAAGAAGACTGCCGAAGAGCCAGCTGCCTCTGGCCGCAT CATCTGTCACAGTTACCTGGAGAGGCTCCTGAATGTTGAGGTGCCCCAGAAAGTTGGTTCTGAGCAGAAGGAACCCCCCGAGGAGGCTGA GCCTGTGGCGGCAGCTGAGCCAGAGGTCCCTGAGAACAATGGAAATAACTCGTGGCCCCACAATGACACGGAGATTGCCAACAGCACACC CAACCCGAAGCCTGCAGCCAGCAGCCCGGAAACACCCTCTGCAGGGCAGCAAGAGGCCAAGACGGACCAAGCAGATGGACCCAGAGAGCC ACCGCAGAGTGCCAGGAGGAAGCGCAGCTACAAGCAGGCCGTGAGTGAGCTGGACGAGGAGCAGCACCTGGAGGATGAGGAGCTGCAGCC CCCCAGGAGCAAGACCCCTTCCTCACCCTGCCCAGCCAGCAAGGTGGTACGGCCCCTCCGGACCTTTCTGCACACAGTGCAGAGGAACCA GATGCTCATGACCCCGACCTCAGCCCCACGCAGCGTCATGAAGTCCTTTATTAAGCGCAACACTCCCCTGCGCATGGACCCCAAGCACCG CGGAGACCTGGGCAATGTCCGTGCTGATGCTGACGGCCGCGCCATCTTCAGAATGGAGGATGAGCAGCTGAAGGTGTGGGATGTGATTGG CCGCAGCCTGATTATTGATGAGGGAGAAGATGACCTGGGCCGGGGAGGCCATCCCTTATCCAAGATCACAGGGAACTCCGGGGAGAGGTT GGCCTGTGGCATCATTGCACGCTCCGCTGGCCTTTTCCAGAACCCCAAGCAGATCTGCTCTTGCGATGGCCTCACCATCTGGGAGGAGCG AGGCCGGCCCATCGCTGGCAAGGGCCGAAAGGAGTCAGCGCAGCCCCCTGCCCACCTTTGAGCAGGACCTCACCTTGGCTCTGTTGCTGT CCTCCAGGGCGAGCACTTTCCACTTCCAGAGGGGGCCAGAGGGACTTTGCCTGCCCAGTCTTTGGAGAGCTCAGTACAGGGCAGGAGCTG >In-frame_INCENP_ENST00000394818_chr11_61908516_+_CCS_ENST00000310190_chr11_66372810_+_2195nt CTTGCCGAGGATTGGCTGAGCCTTCAGTTTTGAAAATCATAGTTTTCGCCCGCGCTGCGCCGCCTGGTTGCTCCTCCCGTGCGGTGAGTC CCGAAGGCCCGGAGCCAAGTGGGTCTGGGCAAGCGGGGCCTTACCTAGGGATACCACCGGACTTGGATCGGAGCAGCCTTCAGGGGACGT GGCGCAGTCGAACAGAGCCACCATGGGGACGACGGCCCCAGGGCCCATTCACCTGCTGGAGCTATGTGACCAGAAGCTCATGGAGTTTCT CTGCAACATGGATAATAAGGACTTGGTGTGGCTTGAGGAAATCCAAGAGGAGGCCGAGCGCATGTTCACCAGAGAATTCAGCAAAGAGCC AGAGCTGATGCCCAAAACACCTTCTCAGAAGAACCGACGGAAGAAGAGACGGATTTCTTATGTTCAGGATGAAAACAGAGATCCCATCAG GAGAAGGTTATCCCGCAGAAAGTCTCGGAGCAGCCAGCTGAGCTCCCGACGCCTCCGCAGCAAGGACAGTGTAGAGAAGCTGGCTACAGT GGTCGGGGAGAACGGCTCCGTCCTGCGGCGTGTGACCCGTGCTGCGGCTGCAGCTGCCGCGGCTACCATGGCATTGGCTGCACCTTCTTC ACCCACCCCTGAGTCTCCCACGATGCTGACTAAGAAGCCCGAGGATAACCACACCCAGTGCCAGCTGGTGCCTGTGGTGGAGATCGGCAT CAGTGAGCGCCAGAATGCTGAGCAGCATGTCACCCAGCTCATGTCCACCGAGCCTCTGCCCCGCACTCTGTCCCCGACTCCAGCTTCAGC CACAGCTCCAACCTCCCAGGGCATCCCGACATCAGATGAGGAATCAACACCTAAGAAGTCGAAGGCCAGGATACTGGAGTCCATCACAGT GAGCTCCCTGATGGCTACACCCCAGGACCCCAAGGGTCAAGGGGTCGGGACGGGGCGGTCTGCGTCTAAGCTCAGGATTGCGCAGGTCTC CCCTGGCCCACGGGACTCGCCAGCCTTTCCAGATTCTCCATGGCGGGAGCGGGTGCTGGCTCCCATCCTGCCGGATAACTTCTCCACGCC CACGGGCTCTCGCACGGACTCTCAATCGGTGCGGCACAGCCCGATCGCCCCGTCTTCCCCGAGTCCCCAAGTCTTAGCCCAGAAGTACTC TCTGGTGGCCAAACAGGAAAGTGTTGTCCGCAGGGCGAGCAGAAGGCTTGCCAAGAAGACTGCCGAAGAGCCAGCTGCCTCTGGCCGCAT CATCTGTCACAGTTACCTGGAGAGGCTCCTGAATGTTGAGGTGCCCCAGAAAGTTGGTTCTGAGCAGAAGGAACCCCCCGAGGAGGCTGA GCCTGTGGCGGCAGCTGAGCCAGAGGTCCCTGAGAACAATGGAAATAACTCGTGGCCCCACAATGACACGGAGATTGCCAACAGCACACC CAACCCGAAGCCTGCAGCCAGCAGCCCGGAAACACCCTCTGCAGGGCAGCAAGAGGCCAAGACGGACCAAGCAGATGGACCCAGAGAGCC ACCGCAGAGTGCCAGGAGGAAGCGCAGCTACAAGCAGGCCGTGAGTGAGCTGGACGAGGAGCAGCACCTGGAGGATGAGGAGCTGCAGCC CCCCAGGAGCAAGACCCCTTCCTCACCCTGCCCAGCCAGCAAGGTGGTACGGCCCCTCCGGACCTTTCTGCACACAGTGCAGAGGAACCA GATGCTCATGACCCCGACCTCAGCCCCACGCAGCGTCATGAAGTCCTTTATTAAGCGCAACACTCCCCTGCGCATGGACCCCAAGCACCG CGGAGACCTGGGCAATGTCCGTGCTGATGCTGACGGCCGCGCCATCTTCAGAATGGAGGATGAGCAGCTGAAGGTGTGGGATGTGATTGG CCGCAGCCTGATTATTGATGAGGGAGAAGATGACCTGGGCCGGGGAGGCCATCCCTTATCCAAGATCACAGGGAACTCCGGGGAGAGGTT GGCCTGTGGCATCATTGCACGCTCCGCTGGCCTTTTCCAGAACCCCAAGCAGATCTGCTCTTGCGATGGCCTCACCATCTGGGAGGAGCG AGGCCGGCCCATCGCTGGCAAGGGCCGAAAGGAGTCAGCGCAGCCCCCTGCCCACCTTTGAGCAGGACCTCACCTTGGCTCTGTTGCTGT >In-frame_INCENP_ENST00000278849_chr11_61908516_+_CCS_ENST00000533244_chr11_66372810_+_2270nt AGTTTTGAAAATCATAGTTTTCGCCCGCGCTGCGCCGCCTGGTTGCTCCTCCCGTGCGGTGAGTCCCGAAGGCCCGGAGCCAAGTGGGTC TGGGCAAGCGGGGCCTTACCTAGGGATACCACCGGACTTGGATCGGAGCAGCCTTCAGGGGACGTGGCGCAGTCGAACAGAGCCACCATG GGGACGACGGCCCCAGGGCCCATTCACCTGCTGGAGCTATGTGACCAGAAGCTCATGGAGTTTCTCTGCAACATGGATAATAAGGACTTG GTGTGGCTTGAGGAAATCCAAGAGGAGGCCGAGCGCATGTTCACCAGAGAATTCAGCAAAGAGCCAGAGCTGATGCCCAAAACACCTTCT CAGAAGAACCGACGGAAGAAGAGACGGATTTCTTATGTTCAGGATGAAAACAGAGATCCCATCAGGAGAAGGTTATCCCGCAGAAAGTCT CGGAGCAGCCAGCTGAGCTCCCGACGCCTCCGCAGCAAGGACAGTGTAGAGAAGCTGGCTACAGTGGTCGGGGAGAACGGCTCCGTCCTG CGGCGTGTGACCCGTGCTGCGGCTGCAGCTGCCGCGGCTACCATGGCATTGGCTGCACCTTCTTCACCCACCCCTGAGTCTCCCACGATG CTGACTAAGAAGCCCGAGGATAACCACACCCAGTGCCAGCTGGTGCCTGTGGTGGAGATCGGCATCAGTGAGCGCCAGAATGCTGAGCAG CATGTCACCCAGCTCATGTCCACCGAGCCTCTGCCCCGCACTCTGTCCCCGACTCCAGCTTCAGCCACAGCTCCAACCTCCCAGGGCATC CCGACATCAGATGAGGAATCAACACCTAAGAAGTCGAAGGCCAGGATACTGGAGTCCATCACAGTGAGCTCCCTGATGGCTACACCCCAG GACCCCAAGGGTCAAGGGGTCGGGACGGGGCGGTCTGCGTCTAAGCTCAGGATTGCGCAGGTCTCCCCTGGCCCACGGGACTCGCCAGCC TTTCCAGATTCTCCATGGCGGGAGCGGGTGCTGGCTCCCATCCTGCCGGATAACTTCTCCACGCCCACGGGCTCTCGCACGGACTCTCAA TCGGTGCGGCACAGCCCGATCGCCCCGTCTTCCCCGAGTCCCCAAGTCTTAGCCCAGAAGTACTCTCTGGTGGCCAAACAGGAAAGTGTT GTCCGCAGGGCGAGCAGAAGGCTTGCCAAGAAGACTGCCGAAGAGCCAGCTGCCTCTGGCCGCATCATCTGTCACAGTTACCTGGAGAGG CTCCTGAATGTTGAGGTGCCCCAGAAAGTTGGTTCTGAGCAGAAGGAACCCCCCGAGGAGGCTGAGCCTGTGGCGGCAGCTGAGCCAGAG GTCCCTGAGAACAATGGAAATAACTCGTGGCCCCACAATGACACGGAGATTGCCAACAGCACACCCAACCCGAAGCCTGCAGCCAGCAGC CCGGAAACACCCTCTGCAGGGCAGCAAGAGGCCAAGACGGACCAAGCAGATGGACCCAGAGAGCCACCGCAGAGTGCCAGGAGGAAGCGC AGCTACAAGCAGGCCGTGAGTGAGCTGGACGAGGAGCAGCACCTGGAGGATGAGGAGCTGCAGCCCCCCAGGAGCAAGACCCCTTCCTCA CCCTGCCCAGCCAGCAAGGTGGTACGGCCCCTCCGGACCTTTCTGCACACAGTGCAGAGGAACCAGATGCTCATGACCCCGACCTCAGCC CCACGCAGCGTCATGAAGTCCTTTATTAAGCGCAACACTCCCCTGCGCATGGACCCCAAGCACCGCGGAGACCTGGGCAATGTCCGTGCT GATGCTGACGGCCGCGCCATCTTCAGAATGGAGGATGAGCAGCTGAAGGTGTGGGATGTGATTGGCCGCAGCCTGATTATTGATGAGGGA GAAGATGACCTGGGCCGGGGAGGCCATCCCTTATCCAAGATCACAGGGAACTCCGGGGAGAGGTTGGCCTGTGGCATCATTGCACGCTCC GCTGGCCTTTTCCAGAACCCCAAGCAGATCTGCTCTTGCGATGGCCTCACCATCTGGGAGGAGCGAGGCCGGCCCATCGCTGGCAAGGGC CGAAAGGAGTCAGCGCAGCCCCCTGCCCACCTTTGAGCAGGACCTCACCTTGGCTCTGTTGCTGTCCTCCAGGGCGAGCACTTTCCACTT CCAGAGGGGGCCAGAGGGACTTTGCCTGCCCAGTCTTTGGAGAGCTCAGTACAGGGCAGGAGCTGCTGTGGTGTTCCCTTGGCAAATGAA >In-frame_INCENP_ENST00000278849_chr11_61908516_+_CCS_ENST00000310190_chr11_66372810_+_2170nt AGTTTTGAAAATCATAGTTTTCGCCCGCGCTGCGCCGCCTGGTTGCTCCTCCCGTGCGGTGAGTCCCGAAGGCCCGGAGCCAAGTGGGTC TGGGCAAGCGGGGCCTTACCTAGGGATACCACCGGACTTGGATCGGAGCAGCCTTCAGGGGACGTGGCGCAGTCGAACAGAGCCACCATG GGGACGACGGCCCCAGGGCCCATTCACCTGCTGGAGCTATGTGACCAGAAGCTCATGGAGTTTCTCTGCAACATGGATAATAAGGACTTG GTGTGGCTTGAGGAAATCCAAGAGGAGGCCGAGCGCATGTTCACCAGAGAATTCAGCAAAGAGCCAGAGCTGATGCCCAAAACACCTTCT CAGAAGAACCGACGGAAGAAGAGACGGATTTCTTATGTTCAGGATGAAAACAGAGATCCCATCAGGAGAAGGTTATCCCGCAGAAAGTCT CGGAGCAGCCAGCTGAGCTCCCGACGCCTCCGCAGCAAGGACAGTGTAGAGAAGCTGGCTACAGTGGTCGGGGAGAACGGCTCCGTCCTG CGGCGTGTGACCCGTGCTGCGGCTGCAGCTGCCGCGGCTACCATGGCATTGGCTGCACCTTCTTCACCCACCCCTGAGTCTCCCACGATG CTGACTAAGAAGCCCGAGGATAACCACACCCAGTGCCAGCTGGTGCCTGTGGTGGAGATCGGCATCAGTGAGCGCCAGAATGCTGAGCAG CATGTCACCCAGCTCATGTCCACCGAGCCTCTGCCCCGCACTCTGTCCCCGACTCCAGCTTCAGCCACAGCTCCAACCTCCCAGGGCATC CCGACATCAGATGAGGAATCAACACCTAAGAAGTCGAAGGCCAGGATACTGGAGTCCATCACAGTGAGCTCCCTGATGGCTACACCCCAG GACCCCAAGGGTCAAGGGGTCGGGACGGGGCGGTCTGCGTCTAAGCTCAGGATTGCGCAGGTCTCCCCTGGCCCACGGGACTCGCCAGCC TTTCCAGATTCTCCATGGCGGGAGCGGGTGCTGGCTCCCATCCTGCCGGATAACTTCTCCACGCCCACGGGCTCTCGCACGGACTCTCAA TCGGTGCGGCACAGCCCGATCGCCCCGTCTTCCCCGAGTCCCCAAGTCTTAGCCCAGAAGTACTCTCTGGTGGCCAAACAGGAAAGTGTT GTCCGCAGGGCGAGCAGAAGGCTTGCCAAGAAGACTGCCGAAGAGCCAGCTGCCTCTGGCCGCATCATCTGTCACAGTTACCTGGAGAGG CTCCTGAATGTTGAGGTGCCCCAGAAAGTTGGTTCTGAGCAGAAGGAACCCCCCGAGGAGGCTGAGCCTGTGGCGGCAGCTGAGCCAGAG GTCCCTGAGAACAATGGAAATAACTCGTGGCCCCACAATGACACGGAGATTGCCAACAGCACACCCAACCCGAAGCCTGCAGCCAGCAGC CCGGAAACACCCTCTGCAGGGCAGCAAGAGGCCAAGACGGACCAAGCAGATGGACCCAGAGAGCCACCGCAGAGTGCCAGGAGGAAGCGC AGCTACAAGCAGGCCGTGAGTGAGCTGGACGAGGAGCAGCACCTGGAGGATGAGGAGCTGCAGCCCCCCAGGAGCAAGACCCCTTCCTCA CCCTGCCCAGCCAGCAAGGTGGTACGGCCCCTCCGGACCTTTCTGCACACAGTGCAGAGGAACCAGATGCTCATGACCCCGACCTCAGCC CCACGCAGCGTCATGAAGTCCTTTATTAAGCGCAACACTCCCCTGCGCATGGACCCCAAGCACCGCGGAGACCTGGGCAATGTCCGTGCT GATGCTGACGGCCGCGCCATCTTCAGAATGGAGGATGAGCAGCTGAAGGTGTGGGATGTGATTGGCCGCAGCCTGATTATTGATGAGGGA GAAGATGACCTGGGCCGGGGAGGCCATCCCTTATCCAAGATCACAGGGAACTCCGGGGAGAGGTTGGCCTGTGGCATCATTGCACGCTCC GCTGGCCTTTTCCAGAACCCCAAGCAGATCTGCTCTTGCGATGGCCTCACCATCTGGGAGGAGCGAGGCCGGCCCATCGCTGGCAAGGGC CGAAAGGAGTCAGCGCAGCCCCCTGCCCACCTTTGAGCAGGACCTCACCTTGGCTCTGTTGCTGTCCTCCAGGGCGAGCACTTTCCACTT |
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FusionGenePPI for INCENP_CCS |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| INCENP | CDCA8, AURKB, H2AFZ, BIRC5, SGOL1, AURKA, EVI5, SIRT7, HIST2H3C, CBX5, AURKC, HECW2, FLOT1, IFI16, HIST1H2BG, HIST1H3A, EWSR1, PHF8, EGFR, TRIM25 | CCS | SOD1, APBA1, CCS, XIAP, SLC31A1, CAPZA2, SCRN2, ATOX1, GMPPB, GOT1, TXN, PPIL3, RAE1, CUL4B, CDH1, DUSP13 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| Hgene | INCENP | chr11:61908516 | chr11:66372810 | ENST00000278849 | + | 10 | 18 | 124_248 | 531 | 915 | CBX5 |
| Hgene | INCENP | chr11:61908516 | chr11:66372810 | ENST00000394818 | + | 10 | 19 | 124_248 | 531 | 919 | CBX5 |
| Hgene | INCENP | chr11:61908983 | chr11:66372810 | ENST00000394818 | + | 11 | 19 | 124_248 | 535 | 919 | CBX5 |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| Hgene | INCENP | chr11:61908516 | chr11:66372810 | ENST00000278849 | + | 10 | 18 | 822_897 | 531 | 915 | AURKC |
| Hgene | INCENP | chr11:61908516 | chr11:66372810 | ENST00000394818 | + | 10 | 19 | 822_897 | 531 | 919 | AURKC |
| Hgene | INCENP | chr11:61908983 | chr11:66372810 | ENST00000278849 | + | 1 | 18 | 822_897 | -59 | 915 | AURKC |
| Hgene | INCENP | chr11:61908983 | chr11:66372810 | ENST00000394818 | + | 11 | 19 | 822_897 | 535 | 919 | AURKC |
| Hgene | INCENP | chr11:61908983 | chr11:66372810 | ENST00000278849 | + | 1 | 18 | 124_248 | -59 | 915 | CBX5 |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for INCENP_CCS |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
| Tgene | CCS | O14618 | DB01593 | Zinc | Copper chaperone for superoxide dismutase | small molecule | approved|investigational |
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RelatedDiseases for INCENP_CCS |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | INCENP | C0025202 | melanoma | 1 | CTD_human |
| Tgene | CCS | C0019189 | Hepatitis, Chronic | 1 | CTD_human |
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