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FusionGeneSummary

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FusionGeneSequence

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Fusion gene ID: 17304

FusionGeneSummary for IGSF9B_OPCML

check button Fusion gene summary
Fusion gene informationFusion gene name: IGSF9B_OPCML
Fusion gene ID: 17304
HgeneTgene
Gene symbol

IGSF9B

OPCML

Gene ID

22997

4978

Gene nameimmunoglobulin superfamily member 9Bopioid binding protein/cell adhesion molecule like
Synonyms-IGLON1|OBCAM|OPCM
Cytomap

11q25

11q25

Type of geneprotein-codingprotein-coding
Descriptionprotein turtle homolog Bopioid-binding protein/cell adhesion moleculeIgLON family member 1opioid binding protein/cell adhesion molecule-like preprotein
Modification date2018052320180522
UniProtAcc

Q9UPX0

Q14982

Ensembl transtripts involved in fusion geneENST00000533871, ENST00000321016, 
ENST00000564347, 		ENST00000524381, 
ENST00000529038, ENST00000331898, 
ENST00000374778, ENST00000541867, 
Fusion gene scores* DoF score2 X 2 X 2=85 X 4 X 5=100
# samples 25
** MAII scorelog2(2/8*10)=1.32192809488736log2(5/100*10)=-1
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: IGSF9B [Title/Abstract] AND OPCML [Title/Abstract] AND fusion [Title/Abstract]

Functional or gene categories assigned by FusionGDB annotationTumor suppressor gene involved fusion gene, in-frame but not retained their domain.
Tumor suppressor gene involved fusion gene, retained protein feature but frameshift.
DDR (DNA damage repair) gene involved fusion gene, in-frame but not retained their domain.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check button Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
Data typeSourceCancer typeSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
TCGARVSARCTCGA-PC-A5DP-01AIGSF9Bchr11

133815956

-OPCMLchr11

132812905

-
* LD: Li Ding group's fusion gene list
  RV: Roel Verhaak group's fusion gene list
  ChiTaRs fusion database

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000533871ENST00000524381IGSF9Bchr11

133815956

-OPCMLchr11

132812905

-
5CDS-intronENST00000533871ENST00000529038IGSF9Bchr11

133815956

-OPCMLchr11

132812905

-
5CDS-intronENST00000533871ENST00000331898IGSF9Bchr11

133815956

-OPCMLchr11

132812905

-
5CDS-5UTRENST00000533871ENST00000374778IGSF9Bchr11

133815956

-OPCMLchr11

132812905

-
5CDS-5UTRENST00000533871ENST00000541867IGSF9Bchr11

133815956

-OPCMLchr11

132812905

-
Frame-shiftENST00000321016ENST00000524381IGSF9Bchr11

133815956

-OPCMLchr11

132812905

-
5CDS-intronENST00000321016ENST00000529038IGSF9Bchr11

133815956

-OPCMLchr11

132812905

-
5CDS-intronENST00000321016ENST00000331898IGSF9Bchr11

133815956

-OPCMLchr11

132812905

-
5CDS-5UTRENST00000321016ENST00000374778IGSF9Bchr11

133815956

-OPCMLchr11

132812905

-
5CDS-5UTRENST00000321016ENST00000541867IGSF9Bchr11

133815956

-OPCMLchr11

132812905

-
intron-3CDSENST00000564347ENST00000524381IGSF9Bchr11

133815956

-OPCMLchr11

132812905

-
intron-intronENST00000564347ENST00000529038IGSF9Bchr11

133815956

-OPCMLchr11

132812905

-
intron-intronENST00000564347ENST00000331898IGSF9Bchr11

133815956

-OPCMLchr11

132812905

-
intron-5UTRENST00000564347ENST00000374778IGSF9Bchr11

133815956

-OPCMLchr11

132812905

-
intron-5UTRENST00000564347ENST00000541867IGSF9Bchr11

133815956

-OPCMLchr11

132812905

-

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FusionProtFeatures for IGSF9B_OPCML


check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
IGSF9B

Q9UPX0

OPCML

Q14982

Transmembrane protein which is abundantly expressed ininterneurons, where it may regulate inhibitory synapsedevelopment. May mediate homophilic cell adhesion.{ECO:0000250|UniProtKB:D3ZB51, ECO:0000250|UniProtKB:E9PZ19}. Binds opioids in the presence of acidic lipids; probablyinvolved in cell contact.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

.

* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
>>>>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneOPCMLchr11:133815956chr11:132812905ENST00000331898-07136_219-193346DomainNote=Ig-like C2-type 2
TgeneOPCMLchr11:133815956chr11:132812905ENST00000331898-07223_310-193346DomainNote=Ig-like C2-type 3
TgeneOPCMLchr11:133815956chr11:132812905ENST00000331898-0739_126-193346DomainNote=Ig-like C2-type 1
TgeneOPCMLchr11:133815956chr11:132812905ENST00000374778-08136_219-14305DomainNote=Ig-like C2-type 2
TgeneOPCMLchr11:133815956chr11:132812905ENST00000374778-08223_310-14305DomainNote=Ig-like C2-type 3
TgeneOPCMLchr11:133815956chr11:132812905ENST00000374778-0839_126-14305DomainNote=Ig-like C2-type 1
TgeneOPCMLchr11:133815956chr11:132812905ENST00000524381-08136_21920339DomainNote=Ig-like C2-type 2
TgeneOPCMLchr11:133815956chr11:132812905ENST00000524381-08223_31020339DomainNote=Ig-like C2-type 3
TgeneOPCMLchr11:133815956chr11:132812905ENST00000524381-0839_12620339DomainNote=Ig-like C2-type 1

- In-frame and not-retained protein feature among the 13 regional features.
>>>>>>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneIGSF9Bchr11:133815956chr11:132812905ENST00000321016-220924_1342872217Compositional biasNote=Pro-rich
HgeneIGSF9Bchr11:133815956chr11:132812905ENST00000321016-220139_226872217DomainNote=Ig-like 2
HgeneIGSF9Bchr11:133815956chr11:132812905ENST00000321016-220228_320872217DomainNote=Ig-like 3
HgeneIGSF9Bchr11:133815956chr11:132812905ENST00000321016-22024_129872217DomainNote=Ig-like 1
HgeneIGSF9Bchr11:133815956chr11:132812905ENST00000321016-220324_415872217DomainNote=Ig-like 4
HgeneIGSF9Bchr11:133815956chr11:132812905ENST00000321016-220420_504872217DomainNote=Ig-like 5
HgeneIGSF9Bchr11:133815956chr11:132812905ENST00000321016-220512_604872217DomainFibronectin type-III 1
HgeneIGSF9Bchr11:133815956chr11:132812905ENST00000321016-220614_708872217DomainFibronectin type-III 2
HgeneIGSF9Bchr11:133815956chr11:132812905ENST00000321016-22021_722872217Topological domainExtracellular
HgeneIGSF9Bchr11:133815956chr11:132812905ENST00000321016-220744_1349872217Topological domainCytoplasmic
HgeneIGSF9Bchr11:133815956chr11:132812905ENST00000321016-220723_743872217TransmembraneHelical


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FusionGeneSequence for IGSF9B_OPCML


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.
>In-frame_IGSF9B_ENST00000533871_chr11_133815956_-_OPCML_ENST00000524381_chr11_132812905_-_406aa
MIWYVATFIASVIGTRGLAAEGAHGLREEPEFVTARAGESVVLRCDVIHPVTGQPPPYVVEWFKFGVPIPIFIKFGYYPPHVDPEYAGVP
VRSGDATFPKAMDNVTVRQGESATLRCTIDDRVTRVAWLNRSTILYAGNDKWSIDPRVIILVNTPTQYSIMIQNVDVYDEGPYTCSVQTD
NHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGRPEPTVTWRHLSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAA
PDVRKVKITVNYPPYISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATN


* Fusion transcript sequences (only coding sequence (CDS) region).
>In-frame_IGSF9B_ENST00000533871_chr11_133815956_-_OPCML_ENST00000524381_chr11_132812905_-_1218nt
ATGATTTGGTATGTGGCCACTTTCATAGCAAGTGTGATCGGCACCCGAGGGCTTGCGGCTGAAGGCGCCCACGGCCTGCGAGAGGAGCCC
GAGTTTGTGACGGCAAGAGCTGGGGAGAGCGTGGTCCTGCGATGCGACGTGATCCACCCAGTGACGGGACAGCCCCCACCCTATGTCGTA
GAGTGGTTCAAGTTCGGGGTCCCCATCCCTATCTTCATCAAGTTTGGCTACTACCCGCCGCACGTGGACCCTGAGTATGCAGGAGTGCCC
GTGCGCAGCGGAGATGCCACCTTCCCCAAAGCTATGGACAACGTGACGGTCCGGCAGGGGGAGAGCGCCACCCTCAGGTGTACCATAGAT
GACCGGGTAACCCGGGTGGCCTGGCTAAACCGCAGCACCATCCTCTACGCTGGGAATGACAAGTGGTCCATAGACCCTCGTGTGATCATC
CTGGTCAATACACCAACCCAGTACAGCATCATGATCCAAAATGTGGATGTGTATGACGAAGGTCCGTACACCTGCTCTGTGCAGACAGAC
AATCATCCCAAAACGTCCCGGGTTCACCTAATAGTGCAAGTTCCTCCTCAGATCATGAATATCTCCTCAGACATCACTGTGAATGAGGGA
AGCAGTGTGACCCTGCTGTGTCTTGCTATTGGCAGACCAGAGCCAACTGTGACATGGAGACACCTGTCAGTCAAGGAAGGCCAGGGCTTT
GTAAGTGAGGATGAGTACCTGGAGATCTCTGACATCAAGCGAGACCAGTCCGGGGAGTACGAATGCAGCGCGTTGAACGATGTCGCTGCG
CCCGATGTGCGGAAAGTAAAAATCACTGTAAACTATCCTCCCTATATCTCAAAAGCCAAGAACACTGGTGTTTCAGTCGGTCAGAAGGGC
ATCCTGAGCTGTGAAGCCTCTGCAGTCCCCATGGCTGAATTCCAGTGGTTCAAGGAAGAAACCAGGTTAGCCACTGGTCTGGATGGAATG
AGGATTGAAAACAAAGGCCGCATGTCCACTCTGACTTTCTTCAATGTTTCAGAAAAGGATTATGGGAACTATACTTGTGTGGCCACGAAC
AAGCTTGGGAACACCAATGCCAGCATCACATTGTATGGGCCTGGAGCAGTCATTGATGGTGTAAACTCGGCCTCCAGAGCACTGGCTTGT


* Fusion transcript sequences (Full-length transcript).
>In-frame_IGSF9B_ENST00000533871_chr11_133815956_-_OPCML_ENST00000524381_chr11_132812905_-_6661nt
GCTCCGCCCGGGCGAGTAGTGCAGGTGCCGCTGCGCCGGGGCCGGGGAGGCGCGCGCCGAGCCGAGCGGAGCCTAGGAGGGATGGAGAGC
TGGCCACCCGGGCTGCAGGAGCACCGGCGCGGGGCGTAGGCGGCGCGAGGCGGGCGCGAGGCGGGCGCTCGGGCGCGAGGCGCGTGCGGG
CGCGGGAGCACTTTGCGATAGGATGAGGCTCCGGGCTGGCGCGGTAGTACTATGATTTGGTATGTGGCCACTTTCATAGCAAGTGTGATC
GGCACCCGAGGGCTTGCGGCTGAAGGCGCCCACGGCCTGCGAGAGGAGCCCGAGTTTGTGACGGCAAGAGCTGGGGAGAGCGTGGTCCTG
CGATGCGACGTGATCCACCCAGTGACGGGACAGCCCCCACCCTATGTCGTAGAGTGGTTCAAGTTCGGGGTCCCCATCCCTATCTTCATC
AAGTTTGGCTACTACCCGCCGCACGTGGACCCTGAGTATGCAGGAGTGCCCGTGCGCAGCGGAGATGCCACCTTCCCCAAAGCTATGGAC
AACGTGACGGTCCGGCAGGGGGAGAGCGCCACCCTCAGGTGTACCATAGATGACCGGGTAACCCGGGTGGCCTGGCTAAACCGCAGCACC
ATCCTCTACGCTGGGAATGACAAGTGGTCCATAGACCCTCGTGTGATCATCCTGGTCAATACACCAACCCAGTACAGCATCATGATCCAA
AATGTGGATGTGTATGACGAAGGTCCGTACACCTGCTCTGTGCAGACAGACAATCATCCCAAAACGTCCCGGGTTCACCTAATAGTGCAA
GTTCCTCCTCAGATCATGAATATCTCCTCAGACATCACTGTGAATGAGGGAAGCAGTGTGACCCTGCTGTGTCTTGCTATTGGCAGACCA
GAGCCAACTGTGACATGGAGACACCTGTCAGTCAAGGAAGGCCAGGGCTTTGTAAGTGAGGATGAGTACCTGGAGATCTCTGACATCAAG
CGAGACCAGTCCGGGGAGTACGAATGCAGCGCGTTGAACGATGTCGCTGCGCCCGATGTGCGGAAAGTAAAAATCACTGTAAACTATCCT
CCCTATATCTCAAAAGCCAAGAACACTGGTGTTTCAGTCGGTCAGAAGGGCATCCTGAGCTGTGAAGCCTCTGCAGTCCCCATGGCTGAA
TTCCAGTGGTTCAAGGAAGAAACCAGGTTAGCCACTGGTCTGGATGGAATGAGGATTGAAAACAAAGGCCGCATGTCCACTCTGACTTTC
TTCAATGTTTCAGAAAAGGATTATGGGAACTATACTTGTGTGGCCACGAACAAGCTTGGGAACACCAATGCCAGCATCACATTGTATGGG
CCTGGAGCAGTCATTGATGGTGTAAACTCGGCCTCCAGAGCACTGGCTTGTCTCTGGCTATCAGGGACCCTCTTAGCCCACTTCTTCATC
AAGTTTTGATAAGAAATCCTAGGTCCTCTGAGCAACGCCTGCTTCTCCATATCACAGACTTTAATCTACACTGCGGAGAGCAAACCAGCT
TGGGCTTCTTTTTGTTTTTTTCTGTTATTCTAGATTTGTTTTCTTTTTGTTTTTGTTTATTTGTTTGTTTGCTTTTATTTCCAGCTTGAA
TGAGTGGGGTTGGGGGCGGGGTGGGCAGGGTTCTACCACGTGTAGGATAATCATTCATTGGTGTGTCCAAAAATGGGGTCTGCTCCTGCT
ACCTTGACCCTTCCCTTTCCTCTGCTTCTCTCCTCATCATCATTCCCAACAACATCCTCTGCCACACACAACAAAACGTAAGTTTCATTT
GGGCAAAAATTGAGCCTCACAATAAACACCCTGAAGACACAACTTGACTTATAACATAGTGCACAGCAAGAGCTACATCCAAGTGTCCTA
TTATCTGTGATTATTTTCTTAATGACAATGTACATATGCCCCCATCCATGTTAATTATTATCTAATTCCATTAGGGTTCACGTCTTTTCT
TTCTGGGACACTATCCTACTATATCCATATCTATAGATTTCAATATAGATGATTGTGCCATCTTCTGTAGCCCCTCCGCTCTACTCATTC
CTTCCACCATCTGCAGAGATTTGAAGTTTGGGGCTATGCATGAAACCCAACACTAAATTTTGCAAGTCAAGTAACCAAAAAAGGGGGAGG
CATTTTGAAGATAGAACCTCTATTTTAAAAAGAGAAGTTCAACTCATAAACGTGATTGATAGGTGGCTGATTTATTTAGGTTTTGTCAAG
CTATCTATCAAAGTAATGGTACAGTTACCCATCTACTCAAATATCTGATTTATCTCACCATCCAATTATCTACCCACCTGTCTTCCTCTC
TAGCAATCTATTTACTGTTTATCAATCTATCAATGTAATTGTCTAACACTCCTTTCTATTCTCTCCCTACTACTCACTATCAATTCATCC
CCATATGAATCTCTAACCATATTGTATCTCTCCCACTGTATTCATTTATACACCATCAGCAGACATTGGCATCTTCAAAATTATCTTTCA
ACTTCTGTGAAAGCCAACGATCTCACAGGTTAACAAAATACAAAAGCAATACCCTGTGTTGTGGACTCTTTAAAATCTGGTATCCTATCC
ACCCAAGGGAGACACTAACAGATAGGCCAAAGTAGCAAGCTAATGATCAGTCACTCACTATTCCCAGAAGAGCCTGTGTTTTCTAAAACA
CTTTCTTGGGAAGCAGATCAGCCTAGAAAAGTTTTGATTAGCACTGTGGTTTTCCTTTTGCACTTGAAGGACAAAGGTGCCAGCCTTTAT
GCTTCTCTCAACCCTTCAAGAAAGTACATGTCAGGAACCTATGGCTGGCTTTCCTTAGCAGCAAGAACTTGAGAGAAAAACACATCTGTC
TCTGCAATGCAAAGTGAAGAGTCCACCCGCCTGAGTGGGATGACTTCAGCTAGAGTCTCCTTTCTGCTCCAGTTCTGGTTTAATCTGTTT
GAAAACTATCCAGTAAAAAGCTGATGGAGGCCAATTACATGGCGGGTGTATTGACAACTCTGGTATTTGTTTCAGGAAGCTCTTCTAAGC
TGAGGGCACTTGAGCAACTGACTTAATTTTCAAGCACTTGATTAACACAACACTGCAAACAGAAGGGAGAAAGTGTCAGTGACACAGTTT
CCTCTGATGCAGCTGCTTCTCCAATGGCTTTGGGGAAGAACTTCACCAGCTCTTCAGGTTCAAAGCAGACCCAGCATACAAACAAGAGCT
GAGCCACCTTTGCTGTCTTGTCTCCTGGGACGAGAAGGACTCATCCAGCAAAGTTGCCTGGGATTCAAAATAAAGGCATTGCAGACCGCA
CAGGTGTGCTGCAGGGACTGATCCACAGAGAGGATGAGAATGCAGCATCAATCGCAGACCTGCCCTGCCTCAGTTGGAAAACCTTTTCAG
GCCCTCAGTCTAAAAAATAAAAAATATGAGCACCATTGAATTCTGTGCCCTTAATGCTTAACTGGTCTTCTTCCTCTGGTATCAGTGTCC
TCTTTGTTTTTGTCCATCAAGGCACATGAGTGTGACCTCTGCCATGGGGAAACACACACAGAGATATCTATACATATATACATACATACA
AACATAGGCTATCTTGGCACACTAAATGCTAAGCACTGTCTTAAGAGGTAGAGCTGGTGTGAGTGAAATTAATGTTACATTTTCCAGCTG
TAAACAGACATCTGCATTTCCTAGTGAGCTGCCAGGAGCCAGATTCGGGAACCGTAACTGATGTGCCAGGAATGGTGCATTGATTCCCAG
TTCCAGGGATGATCATGAGCAGGCGCAAAATCAGAATTAAAGGTCGCACATAGACGTTTCAGATCTGTCACCACCTTCAGCATCTGGAGT
TGAGTTGGTGTCAGATAGTGTATGAGAATTAAATGTGTCATCTGAGCATGCTACTGATGATAAATTTGTTACTTTGGAGTTGAATAAATG
TGAAGGCTGTGAAGAGTGGACAGTCTTGGAGAACACAGTGCTTGAAATGGACAAGCTGGACCTATTCCTCACTCCAAGACTTGTTCTACA
GGAAAGGGTCCATGCTCCTTTGGCCAAGATCATCAGAACCTCTCAACCCAACAAGGCTGGCTTCAGGGCCACTATGGAACCCTGCTGTTC
CCCCTTCCAAAGGATACTAAGATGCCCCTCTGGTGGGTACCTATCCCAGCCACGTTTCAGAGGGAGAGAAATGCTACAGTTGATCCTCAT
CTGTCTGGGGTAAAGACAACAAAGTAAATACAACCCAAGGCAACTGGGGTACTCACTGGGAGTGAAAATGACTTCTTCACAACAGACATA
TTTCTGCTTCTGTGTTTTTGTGTTTCTTTGGTGGGGATGGCTTCATGGGAGAGTGGCTGTCACCCATCATTTTGAAGCATATAGAACAAC
AAATGCTTACACAAGACAATATCCACACTTTTCCAACTTCACACACGGAGAGTACATGGAGAATGCCTACAGGCTAGATTTGTTCAGGGT
GCCAGTAGTGGGCATGGGGTGGGGGCAAGGCAGGACAAAACATACAAGTCTGAGCAAGTACATCTCTTGCAGGTTTTCCACATGAAAAGG
AAGCCAAATAAGTCCTGTTAGGAGATTAGGTGAGAGGAATTAGCAATGTAGGGACTCTGAAACCCTTCCCCTTCCCAAAACAGAGTTCAT
ATGCACTTCCACCAAAGTAATGCCAATGAAAGTGCTCGTGTTAAGGCTGCAGCCAAGCTTGTTTTTCAGTAGTTTAATGTCAAGTGCCTG
ATACAGTCGACTGCAAGTCTAAACAAGCATGTTTAGTTTTTCTCATTCTTGCTTTAATTCAGGGAGGGGGAGATGTAGAGAAGTGGTTGT
GAAAACATGTACAGGCTTTATGCAGAGCACTGCGCATGGCTGTTCTGCTGCAACTGTGCTCCACGAAACAGAAGAAAAGGTAAGGTGTTG
TGTCACAAAGAGGCCCCAGTCTCTTTCTTCTTACATCCATGCCTCTTACTAGATGATACATTTACAGATTGGGCAGTTTGTTCTCAAAAC
CTGGGTGAGAAGACTATTCCTGGACTCTAGCAACTTCAAAACTGAGGCTGGGTTTCAGAATCTTTTTCTGCATCAATTCAGTCAATTTGC
CTTCAACAAAGAGAAGTCAGCAAGTTCTATTTATGCTGAAAGAACTATTCCATGAGAAAAGCAGAGAACCCCAAAGTGGGCAGGCAACCC
CGACGAGAGCTTATCCCTGTGGCGGCATCAGGAGTGGCTGTACATTGAATTTTCAAGTGCTGGTTGGCTGTCGCCAGCCCATGGTAGGAG
GGGAGGAATGGCTTAAGATGAGGTAAGATCTGGTGGTGGGGCATCTTTCCTCAATTCCATACTGACTTTGATCTTGAGAAAGAAAAACTG
GCTATGCATTACCTAAAACCAGTCCAAAATGAAACAGACCAACACACACACAAAAGCAAATTGTCAATCCCTTTGGAATTAAGGGAAGCA
GCATAAGGTTTTTCTTTTTGGAAAAAATGCATTTATTTTCTTTTTCTCCAACAGCAAGAATCTTTTGTTTTCATTTTGCACGTGACCTTA
TCTTGGAAACTCTTATACCCAATTGCCTCCCCTCCTATTATTCAGAGCTTCCCTGTCTTTTTACTTGAAGACAAATAAGTTTGAGCACTT
GAGTAAAACTTCACAGGTGTGTAAGTAGGAAGGCAACATTTTCAAAAAGAGACCATATGATGAGAACGCCTAATGATCACCACATGCAAA
CAAACAAAACTGCCAGTCTCATTTCCCACATTTCTTACTTAAGAGAAGAGAAGTAAATGAAAGGAAGAAGAAATAGATTTGTAATTAAAG
ATGTGGCAAAAAAGATAGGGCTGAGCCAGTTCAATTTAGCCTTCAGGTGCAGAATACTTAGAGTCCAAAGAAATGTGGAGTGGACTTAAT
TAGATGCAGTTGTCTTTATCCTGAAAGTAGTGAGCTAAGCCTAATTTCCAGCATTTTGAAAGAGATTCCTTTTTGTTTCTTTCCATGGTG
CCCTCTTTAAGGCACAGAGTTGCTCCACACCACTGGGTGGAGAAAGAAAGATTGCGAACCCTCGACCATCCTTTTGAGGCTACATTCTAT
GTTATTTGGCAGATTTATAAAGCTATCAGTAATAACAATGCTATGTACTGCAAGCTGCCCTTGTGTTAGTTAAAGGGAGCATTTTTAATC
GTTCGGAAATTTTCGTGACATGTCAAGTGCAGTTGTGAGGACTGTGTGGGTGAACGAAAATGTGTCTGTCAAGTTCAGAGTCCTTTAGAT
TTAAAAAAAAATTATGACTTATCAATGGTGCCGTTATAGCTGTGTCAGACAATGGGTGTGCCCATTCTCACAATTATCCTTCAAAAAAAA
TCTATGTTCAAATGCTTTAAAAATTTATCACACGATACAAGAGTATGACTTTGTCAGCCTTCTAGAGTTCTTTTTTTCTTTTATTTTCTT
TCGTATTTTTTCCTTCAAAAAATCAATGAAGACTTGATTTCTGTCAATAATTGTATCAAGGGTGAATATACTACCTGAATTTTGTGCATG
TTACATTGTAGTTGTAACCTTTTCTAATTCAGGATGAATACGAGATGGTTGTGATTGTGCAGTGTACCAATAAAGTTCGAGAAATTTGTA


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FusionGenePPI for IGSF9B_OPCML


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page

.

check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors
IGSF9BOPCMLATXN1, KRT40, KRTAP10-3, NTM, MBLAC2, TRIP12, TMEM214, CANX, NCAM1, FBXO2


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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RelatedDrugs for IGSF9B_OPCML


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for IGSF9B_OPCML


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
TgeneOPCMLC0036341Schizophrenia1PSYGENET
TgeneOPCMLC1140680Malignant neoplasm of ovary1UNIPROT