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Fusion gene ID: 17210 |
FusionGeneSummary for IGFBP7_SPATA22 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: IGFBP7_SPATA22 | Fusion gene ID: 17210 | Hgene | Tgene | Gene symbol | IGFBP7 | SPATA22 | Gene ID | 3490 | 84690 |
| Gene name | insulin like growth factor binding protein 7 | spermatogenesis associated 22 | |
| Synonyms | AGM|FSTL2|IBP-7|IGFBP-7|IGFBP-7v|IGFBPRP1|MAC25|PSF|RAMSVPS|TAF | NYD-SP20|NYDSP20 | |
| Cytomap | 4q12 | 17p13.2 | |
| Type of gene | protein-coding | protein-coding | |
| Description | insulin-like growth factor-binding protein 7IGF-binding protein 7IGFBP-rP1PGI2-stimulating factorangiomodulinprostacyclin-stimulating factortumor-derived adhesion factor | spermatogenesis-associated protein 22testicular tissue protein Li 186testis development protein NYD-SP20 | |
| Modification date | 20180522 | 20180519 | |
| UniProtAcc | Q16270 | Q8NHS9 | |
| Ensembl transtripts involved in fusion gene | ENST00000295666, ENST00000537922, ENST00000512512, | ENST00000541913, ENST00000397168, ENST00000572969, ENST00000355380, ENST00000575375, ENST00000573128, ENST00000268981, | |
| Fusion gene scores | * DoF score | 5 X 5 X 2=50 | 3 X 3 X 3=27 |
| # samples | 5 | 3 | |
| ** MAII score | log2(5/50*10)=0 | log2(3/27*10)=0.15200309344505 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
| Context | PubMed: IGFBP7 [Title/Abstract] AND SPATA22 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | Oncogene involved fusion gene, in-frame and retained their domain. Tumor suppressor gene involved fusion gene, in-frame but not retained their domain. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | IGFBP7 | GO:0007155 | cell adhesion | 8117260 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | SKCM | TCGA-ER-A197-06A | IGFBP7 | chr4 | 57906990 | - | SPATA22 | chr17 | 3349895 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000295666 | ENST00000541913 | IGFBP7 | chr4 | 57906990 | - | SPATA22 | chr17 | 3349895 | - |
| In-frame | ENST00000295666 | ENST00000397168 | IGFBP7 | chr4 | 57906990 | - | SPATA22 | chr17 | 3349895 | - |
| In-frame | ENST00000295666 | ENST00000572969 | IGFBP7 | chr4 | 57906990 | - | SPATA22 | chr17 | 3349895 | - |
| In-frame | ENST00000295666 | ENST00000355380 | IGFBP7 | chr4 | 57906990 | - | SPATA22 | chr17 | 3349895 | - |
| In-frame | ENST00000295666 | ENST00000575375 | IGFBP7 | chr4 | 57906990 | - | SPATA22 | chr17 | 3349895 | - |
| In-frame | ENST00000295666 | ENST00000573128 | IGFBP7 | chr4 | 57906990 | - | SPATA22 | chr17 | 3349895 | - |
| In-frame | ENST00000295666 | ENST00000268981 | IGFBP7 | chr4 | 57906990 | - | SPATA22 | chr17 | 3349895 | - |
| In-frame | ENST00000537922 | ENST00000541913 | IGFBP7 | chr4 | 57906990 | - | SPATA22 | chr17 | 3349895 | - |
| In-frame | ENST00000537922 | ENST00000397168 | IGFBP7 | chr4 | 57906990 | - | SPATA22 | chr17 | 3349895 | - |
| In-frame | ENST00000537922 | ENST00000572969 | IGFBP7 | chr4 | 57906990 | - | SPATA22 | chr17 | 3349895 | - |
| In-frame | ENST00000537922 | ENST00000355380 | IGFBP7 | chr4 | 57906990 | - | SPATA22 | chr17 | 3349895 | - |
| In-frame | ENST00000537922 | ENST00000575375 | IGFBP7 | chr4 | 57906990 | - | SPATA22 | chr17 | 3349895 | - |
| In-frame | ENST00000537922 | ENST00000573128 | IGFBP7 | chr4 | 57906990 | - | SPATA22 | chr17 | 3349895 | - |
| In-frame | ENST00000537922 | ENST00000268981 | IGFBP7 | chr4 | 57906990 | - | SPATA22 | chr17 | 3349895 | - |
| 5UTR-3CDS | ENST00000512512 | ENST00000541913 | IGFBP7 | chr4 | 57906990 | - | SPATA22 | chr17 | 3349895 | - |
| 5UTR-3CDS | ENST00000512512 | ENST00000397168 | IGFBP7 | chr4 | 57906990 | - | SPATA22 | chr17 | 3349895 | - |
| 5UTR-3CDS | ENST00000512512 | ENST00000572969 | IGFBP7 | chr4 | 57906990 | - | SPATA22 | chr17 | 3349895 | - |
| 5UTR-3CDS | ENST00000512512 | ENST00000355380 | IGFBP7 | chr4 | 57906990 | - | SPATA22 | chr17 | 3349895 | - |
| 5UTR-3CDS | ENST00000512512 | ENST00000575375 | IGFBP7 | chr4 | 57906990 | - | SPATA22 | chr17 | 3349895 | - |
| 5UTR-3CDS | ENST00000512512 | ENST00000573128 | IGFBP7 | chr4 | 57906990 | - | SPATA22 | chr17 | 3349895 | - |
| 5UTR-3CDS | ENST00000512512 | ENST00000268981 | IGFBP7 | chr4 | 57906990 | - | SPATA22 | chr17 | 3349895 | - |
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FusionProtFeatures for IGFBP7_SPATA22 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| IGFBP7 | SPATA22 |
| Binds IGF-I and IGF-II with a relatively low affinity.Stimulates prostacyclin (PGI2) production. Stimulates celladhesion. {ECO:0000269|PubMed:8117260,ECO:0000269|PubMed:8939990}. | Meiosis-specific protein required for homologousrecombination in meiosis I. {ECO:0000250}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | IGFBP7 | chr4:57906990 | chr17:3349895 | ENST00000295666 | - | 2 | 5 | 105_158 | 195 | 283 | Domain | Kazal-like |
| Hgene | IGFBP7 | chr4:57906990 | chr17:3349895 | ENST00000295666 | - | 2 | 5 | 28_106 | 195 | 283 | Domain | IGFBP N-terminal |
| Hgene | IGFBP7 | chr4:57906990 | chr17:3349895 | ENST00000537922 | - | 2 | 4 | 105_158 | 195 | 280 | Domain | Kazal-like |
| Hgene | IGFBP7 | chr4:57906990 | chr17:3349895 | ENST00000537922 | - | 2 | 4 | 28_106 | 195 | 280 | Domain | IGFBP N-terminal |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >IGFBP7 | chr4:57906990 | chr17:3349895 | ENST00000295666 | - | 2 | 5 | 160_264 | 195 | 283 | Domain | Note=Ig-like C2-type |
| Hgene | >IGFBP7 | chr4:57906990 | chr17:3349895 | ENST00000537922 | - | 2 | 4 | 160_264 | 195 | 280 | Domain | Note=Ig-like C2-type |
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FusionGeneSequence for IGFBP7_SPATA22 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_IGFBP7_ENST00000295666_chr4_57906990_-_SPATA22_ENST00000541913_chr17_3349895_-_335aa MERPSLRALLLGAAGLLLLLLPLSSSSSSDTCGPCEPASCPPLPPLGCLLGETRDACGCCPMCARGEGEPCGGGGAGRGYCAPGMECVKS RKRRKGKAGAAAGGPGVSGVCVCKSRYPVCGSDGTTYPSGCQLRAASQRAESRGEKAITQVSKGTCEQGPSIVTPPKDIWNVTGAQVYLS CEVIGIPTPVLIWNKETSLYQLQFKEKASSLRIISAVIESMKYWREHAQKTVLLFEVLAVLDSAVTPGPYYSKTFLMRDGKNTLPCVFYE >In-frame_IGFBP7_ENST00000295666_chr4_57906990_-_SPATA22_ENST00000397168_chr17_3349895_-_335aa MERPSLRALLLGAAGLLLLLLPLSSSSSSDTCGPCEPASCPPLPPLGCLLGETRDACGCCPMCARGEGEPCGGGGAGRGYCAPGMECVKS RKRRKGKAGAAAGGPGVSGVCVCKSRYPVCGSDGTTYPSGCQLRAASQRAESRGEKAITQVSKGTCEQGPSIVTPPKDIWNVTGAQVYLS CEVIGIPTPVLIWNKETSLYQLQFKEKASSLRIISAVIESMKYWREHAQKTVLLFEVLAVLDSAVTPGPYYSKTFLMRDGKNTLPCVFYE >In-frame_IGFBP7_ENST00000295666_chr4_57906990_-_SPATA22_ENST00000572969_chr17_3349895_-_335aa MERPSLRALLLGAAGLLLLLLPLSSSSSSDTCGPCEPASCPPLPPLGCLLGETRDACGCCPMCARGEGEPCGGGGAGRGYCAPGMECVKS RKRRKGKAGAAAGGPGVSGVCVCKSRYPVCGSDGTTYPSGCQLRAASQRAESRGEKAITQVSKGTCEQGPSIVTPPKDIWNVTGAQVYLS CEVIGIPTPVLIWNKETSLYQLQFKEKASSLRIISAVIESMKYWREHAQKTVLLFEVLAVLDSAVTPGPYYSKTFLMRDGKNTLPCVFYE >In-frame_IGFBP7_ENST00000295666_chr4_57906990_-_SPATA22_ENST00000355380_chr17_3349895_-_335aa MERPSLRALLLGAAGLLLLLLPLSSSSSSDTCGPCEPASCPPLPPLGCLLGETRDACGCCPMCARGEGEPCGGGGAGRGYCAPGMECVKS RKRRKGKAGAAAGGPGVSGVCVCKSRYPVCGSDGTTYPSGCQLRAASQRAESRGEKAITQVSKGTCEQGPSIVTPPKDIWNVTGAQVYLS CEVIGIPTPVLIWNKETSLYQLQFKEKASSLRIISAVIESMKYWREHAQKTVLLFEVLAVLDSAVTPGPYYSKTFLMRDGKNTLPCVFYE >In-frame_IGFBP7_ENST00000295666_chr4_57906990_-_SPATA22_ENST00000575375_chr17_3349895_-_335aa MERPSLRALLLGAAGLLLLLLPLSSSSSSDTCGPCEPASCPPLPPLGCLLGETRDACGCCPMCARGEGEPCGGGGAGRGYCAPGMECVKS RKRRKGKAGAAAGGPGVSGVCVCKSRYPVCGSDGTTYPSGCQLRAASQRAESRGEKAITQVSKGTCEQGPSIVTPPKDIWNVTGAQVYLS CEVIGIPTPVLIWNKETSLYQLQFKEKASSLRIISAVIESMKYWREHAQKTVLLFEVLAVLDSAVTPGPYYSKTFLMRDGKNTLPCVFYE >In-frame_IGFBP7_ENST00000295666_chr4_57906990_-_SPATA22_ENST00000573128_chr17_3349895_-_335aa MERPSLRALLLGAAGLLLLLLPLSSSSSSDTCGPCEPASCPPLPPLGCLLGETRDACGCCPMCARGEGEPCGGGGAGRGYCAPGMECVKS RKRRKGKAGAAAGGPGVSGVCVCKSRYPVCGSDGTTYPSGCQLRAASQRAESRGEKAITQVSKGTCEQGPSIVTPPKDIWNVTGAQVYLS CEVIGIPTPVLIWNKETSLYQLQFKEKASSLRIISAVIESMKYWREHAQKTVLLFEVLAVLDSAVTPGPYYSKTFLMRDGKNTLPCVFYE >In-frame_IGFBP7_ENST00000295666_chr4_57906990_-_SPATA22_ENST00000268981_chr17_3349895_-_241aa MERPSLRALLLGAAGLLLLLLPLSSSSSSDTCGPCEPASCPPLPPLGCLLGETRDACGCCPMCARGEGEPCGGGGAGRGYCAPGMECVKS RKRRKGKAGAAAGGPGVSGVCVCKSRYPVCGSDGTTYPSGCQLRAASQRAESRGEKAITQVSKGTCEQGPSIVTPPKDIWNVTGAQVYLS >In-frame_IGFBP7_ENST00000537922_chr4_57906990_-_SPATA22_ENST00000541913_chr17_3349895_-_335aa MERPSLRALLLGAAGLLLLLLPLSSSSSSDTCGPCEPASCPPLPPLGCLLGETRDACGCCPMCARGEGEPCGGGGAGRGYCAPGMECVKS RKRRKGKAGAAAGGPGVSGVCVCKSRYPVCGSDGTTYPSGCQLRAASQRAESRGEKAITQVSKGTCEQGPSIVTPPKDIWNVTGAQVYLS CEVIGIPTPVLIWNKETSLYQLQFKEKASSLRIISAVIESMKYWREHAQKTVLLFEVLAVLDSAVTPGPYYSKTFLMRDGKNTLPCVFYE >In-frame_IGFBP7_ENST00000537922_chr4_57906990_-_SPATA22_ENST00000397168_chr17_3349895_-_335aa MERPSLRALLLGAAGLLLLLLPLSSSSSSDTCGPCEPASCPPLPPLGCLLGETRDACGCCPMCARGEGEPCGGGGAGRGYCAPGMECVKS RKRRKGKAGAAAGGPGVSGVCVCKSRYPVCGSDGTTYPSGCQLRAASQRAESRGEKAITQVSKGTCEQGPSIVTPPKDIWNVTGAQVYLS CEVIGIPTPVLIWNKETSLYQLQFKEKASSLRIISAVIESMKYWREHAQKTVLLFEVLAVLDSAVTPGPYYSKTFLMRDGKNTLPCVFYE >In-frame_IGFBP7_ENST00000537922_chr4_57906990_-_SPATA22_ENST00000572969_chr17_3349895_-_335aa MERPSLRALLLGAAGLLLLLLPLSSSSSSDTCGPCEPASCPPLPPLGCLLGETRDACGCCPMCARGEGEPCGGGGAGRGYCAPGMECVKS RKRRKGKAGAAAGGPGVSGVCVCKSRYPVCGSDGTTYPSGCQLRAASQRAESRGEKAITQVSKGTCEQGPSIVTPPKDIWNVTGAQVYLS CEVIGIPTPVLIWNKETSLYQLQFKEKASSLRIISAVIESMKYWREHAQKTVLLFEVLAVLDSAVTPGPYYSKTFLMRDGKNTLPCVFYE >In-frame_IGFBP7_ENST00000537922_chr4_57906990_-_SPATA22_ENST00000355380_chr17_3349895_-_335aa MERPSLRALLLGAAGLLLLLLPLSSSSSSDTCGPCEPASCPPLPPLGCLLGETRDACGCCPMCARGEGEPCGGGGAGRGYCAPGMECVKS RKRRKGKAGAAAGGPGVSGVCVCKSRYPVCGSDGTTYPSGCQLRAASQRAESRGEKAITQVSKGTCEQGPSIVTPPKDIWNVTGAQVYLS CEVIGIPTPVLIWNKETSLYQLQFKEKASSLRIISAVIESMKYWREHAQKTVLLFEVLAVLDSAVTPGPYYSKTFLMRDGKNTLPCVFYE >In-frame_IGFBP7_ENST00000537922_chr4_57906990_-_SPATA22_ENST00000575375_chr17_3349895_-_335aa MERPSLRALLLGAAGLLLLLLPLSSSSSSDTCGPCEPASCPPLPPLGCLLGETRDACGCCPMCARGEGEPCGGGGAGRGYCAPGMECVKS RKRRKGKAGAAAGGPGVSGVCVCKSRYPVCGSDGTTYPSGCQLRAASQRAESRGEKAITQVSKGTCEQGPSIVTPPKDIWNVTGAQVYLS CEVIGIPTPVLIWNKETSLYQLQFKEKASSLRIISAVIESMKYWREHAQKTVLLFEVLAVLDSAVTPGPYYSKTFLMRDGKNTLPCVFYE >In-frame_IGFBP7_ENST00000537922_chr4_57906990_-_SPATA22_ENST00000573128_chr17_3349895_-_335aa MERPSLRALLLGAAGLLLLLLPLSSSSSSDTCGPCEPASCPPLPPLGCLLGETRDACGCCPMCARGEGEPCGGGGAGRGYCAPGMECVKS RKRRKGKAGAAAGGPGVSGVCVCKSRYPVCGSDGTTYPSGCQLRAASQRAESRGEKAITQVSKGTCEQGPSIVTPPKDIWNVTGAQVYLS CEVIGIPTPVLIWNKETSLYQLQFKEKASSLRIISAVIESMKYWREHAQKTVLLFEVLAVLDSAVTPGPYYSKTFLMRDGKNTLPCVFYE >In-frame_IGFBP7_ENST00000537922_chr4_57906990_-_SPATA22_ENST00000268981_chr17_3349895_-_241aa MERPSLRALLLGAAGLLLLLLPLSSSSSSDTCGPCEPASCPPLPPLGCLLGETRDACGCCPMCARGEGEPCGGGGAGRGYCAPGMECVKS RKRRKGKAGAAAGGPGVSGVCVCKSRYPVCGSDGTTYPSGCQLRAASQRAESRGEKAITQVSKGTCEQGPSIVTPPKDIWNVTGAQVYLS |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_IGFBP7_ENST00000295666_chr4_57906990_-_SPATA22_ENST00000541913_chr17_3349895_-_1005nt ATGGAGCGGCCGTCGCTGCGCGCCCTGCTCCTCGGCGCCGCTGGGCTGCTGCTCCTGCTCCTGCCCCTCTCCTCTTCCTCCTCTTCGGAC ACCTGCGGCCCCTGCGAGCCGGCCTCCTGCCCGCCCCTGCCCCCGCTGGGCTGCCTGCTGGGCGAGACCCGCGACGCGTGCGGCTGCTGC CCTATGTGCGCCCGCGGCGAGGGCGAGCCGTGCGGGGGTGGCGGCGCCGGCAGGGGGTACTGCGCGCCGGGCATGGAGTGCGTGAAGAGC CGCAAGAGGCGGAAGGGTAAAGCCGGGGCAGCAGCCGGCGGTCCGGGTGTAAGCGGCGTGTGCGTGTGCAAGAGCCGCTACCCGGTGTGC GGCAGCGACGGCACCACCTACCCGAGCGGCTGCCAGCTGCGCGCCGCCAGCCAGAGGGCCGAGAGCCGCGGGGAGAAGGCCATCACCCAG GTCAGCAAGGGCACCTGCGAGCAAGGTCCTTCCATAGTGACGCCCCCCAAGGACATCTGGAATGTCACTGGTGCCCAGGTGTACTTGAGC TGTGAGGTCATCGGAATCCCGACACCTGTCCTCATCTGGAACAAGGAAACCTCATTGTATCAGTTACAGTTTAAGGAAAAAGCTAGTTCT TTAAGAATTATTTCTGCAGTTATTGAAAGCATGAAGTATTGGCGTGAACATGCACAGAAAACTGTACTTCTTTTTGAAGTATTAGCTGTT CTTGATTCAGCTGTTACACCTGGCCCATATTATTCGAAGACTTTTCTTATGAGGGATGGGAAAAATACTCTGCCTTGTGTCTTTTATGAA ATCGATCGTGAACTTCCGAGACTGATTAGAGGCCGAGTTCATAGATGTGTTGGCAACTATGACCAGAAAAAGAACATTTTCCAATGTGTT TCTGTCAGACCGGCGTCTGTTTCTGAACAAAAAACTTTCCAGGCATTTGTCAAAATTGCAGATGTTGAGATGCAGTATTATATTAATGTG >In-frame_IGFBP7_ENST00000295666_chr4_57906990_-_SPATA22_ENST00000397168_chr17_3349895_-_1005nt ATGGAGCGGCCGTCGCTGCGCGCCCTGCTCCTCGGCGCCGCTGGGCTGCTGCTCCTGCTCCTGCCCCTCTCCTCTTCCTCCTCTTCGGAC ACCTGCGGCCCCTGCGAGCCGGCCTCCTGCCCGCCCCTGCCCCCGCTGGGCTGCCTGCTGGGCGAGACCCGCGACGCGTGCGGCTGCTGC CCTATGTGCGCCCGCGGCGAGGGCGAGCCGTGCGGGGGTGGCGGCGCCGGCAGGGGGTACTGCGCGCCGGGCATGGAGTGCGTGAAGAGC CGCAAGAGGCGGAAGGGTAAAGCCGGGGCAGCAGCCGGCGGTCCGGGTGTAAGCGGCGTGTGCGTGTGCAAGAGCCGCTACCCGGTGTGC GGCAGCGACGGCACCACCTACCCGAGCGGCTGCCAGCTGCGCGCCGCCAGCCAGAGGGCCGAGAGCCGCGGGGAGAAGGCCATCACCCAG GTCAGCAAGGGCACCTGCGAGCAAGGTCCTTCCATAGTGACGCCCCCCAAGGACATCTGGAATGTCACTGGTGCCCAGGTGTACTTGAGC TGTGAGGTCATCGGAATCCCGACACCTGTCCTCATCTGGAACAAGGAAACCTCATTGTATCAGTTACAGTTTAAGGAAAAAGCTAGTTCT TTAAGAATTATTTCTGCAGTTATTGAAAGCATGAAGTATTGGCGTGAACATGCACAGAAAACTGTACTTCTTTTTGAAGTATTAGCTGTT CTTGATTCAGCTGTTACACCTGGCCCATATTATTCGAAGACTTTTCTTATGAGGGATGGGAAAAATACTCTGCCTTGTGTCTTTTATGAA ATCGATCGTGAACTTCCGAGACTGATTAGAGGCCGAGTTCATAGATGTGTTGGCAACTATGACCAGAAAAAGAACATTTTCCAATGTGTT TCTGTCAGACCGGCGTCTGTTTCTGAACAAAAAACTTTCCAGGCATTTGTCAAAATTGCAGATGTTGAGATGCAGTATTATATTAATGTG >In-frame_IGFBP7_ENST00000295666_chr4_57906990_-_SPATA22_ENST00000572969_chr17_3349895_-_1005nt ATGGAGCGGCCGTCGCTGCGCGCCCTGCTCCTCGGCGCCGCTGGGCTGCTGCTCCTGCTCCTGCCCCTCTCCTCTTCCTCCTCTTCGGAC ACCTGCGGCCCCTGCGAGCCGGCCTCCTGCCCGCCCCTGCCCCCGCTGGGCTGCCTGCTGGGCGAGACCCGCGACGCGTGCGGCTGCTGC CCTATGTGCGCCCGCGGCGAGGGCGAGCCGTGCGGGGGTGGCGGCGCCGGCAGGGGGTACTGCGCGCCGGGCATGGAGTGCGTGAAGAGC CGCAAGAGGCGGAAGGGTAAAGCCGGGGCAGCAGCCGGCGGTCCGGGTGTAAGCGGCGTGTGCGTGTGCAAGAGCCGCTACCCGGTGTGC GGCAGCGACGGCACCACCTACCCGAGCGGCTGCCAGCTGCGCGCCGCCAGCCAGAGGGCCGAGAGCCGCGGGGAGAAGGCCATCACCCAG GTCAGCAAGGGCACCTGCGAGCAAGGTCCTTCCATAGTGACGCCCCCCAAGGACATCTGGAATGTCACTGGTGCCCAGGTGTACTTGAGC TGTGAGGTCATCGGAATCCCGACACCTGTCCTCATCTGGAACAAGGAAACCTCATTGTATCAGTTACAGTTTAAGGAAAAAGCTAGTTCT TTAAGAATTATTTCTGCAGTTATTGAAAGCATGAAGTATTGGCGTGAACATGCACAGAAAACTGTACTTCTTTTTGAAGTATTAGCTGTT CTTGATTCAGCTGTTACACCTGGCCCATATTATTCGAAGACTTTTCTTATGAGGGATGGGAAAAATACTCTGCCTTGTGTCTTTTATGAA ATCGATCGTGAACTTCCGAGACTGATTAGAGGCCGAGTTCATAGATGTGTTGGCAACTATGACCAGAAAAAGAACATTTTCCAATGTGTT TCTGTCAGACCGGCGTCTGTTTCTGAACAAAAAACTTTCCAGGCATTTGTCAAAATTGCAGATGTTGAGATGCAGTATTATATTAATGTG >In-frame_IGFBP7_ENST00000295666_chr4_57906990_-_SPATA22_ENST00000355380_chr17_3349895_-_1005nt ATGGAGCGGCCGTCGCTGCGCGCCCTGCTCCTCGGCGCCGCTGGGCTGCTGCTCCTGCTCCTGCCCCTCTCCTCTTCCTCCTCTTCGGAC ACCTGCGGCCCCTGCGAGCCGGCCTCCTGCCCGCCCCTGCCCCCGCTGGGCTGCCTGCTGGGCGAGACCCGCGACGCGTGCGGCTGCTGC CCTATGTGCGCCCGCGGCGAGGGCGAGCCGTGCGGGGGTGGCGGCGCCGGCAGGGGGTACTGCGCGCCGGGCATGGAGTGCGTGAAGAGC CGCAAGAGGCGGAAGGGTAAAGCCGGGGCAGCAGCCGGCGGTCCGGGTGTAAGCGGCGTGTGCGTGTGCAAGAGCCGCTACCCGGTGTGC GGCAGCGACGGCACCACCTACCCGAGCGGCTGCCAGCTGCGCGCCGCCAGCCAGAGGGCCGAGAGCCGCGGGGAGAAGGCCATCACCCAG GTCAGCAAGGGCACCTGCGAGCAAGGTCCTTCCATAGTGACGCCCCCCAAGGACATCTGGAATGTCACTGGTGCCCAGGTGTACTTGAGC TGTGAGGTCATCGGAATCCCGACACCTGTCCTCATCTGGAACAAGGAAACCTCATTGTATCAGTTACAGTTTAAGGAAAAAGCTAGTTCT TTAAGAATTATTTCTGCAGTTATTGAAAGCATGAAGTATTGGCGTGAACATGCACAGAAAACTGTACTTCTTTTTGAAGTATTAGCTGTT CTTGATTCAGCTGTTACACCTGGCCCATATTATTCGAAGACTTTTCTTATGAGGGATGGGAAAAATACTCTGCCTTGTGTCTTTTATGAA ATCGATCGTGAACTTCCGAGACTGATTAGAGGCCGAGTTCATAGATGTGTTGGCAACTATGACCAGAAAAAGAACATTTTCCAATGTGTT TCTGTCAGACCGGCGTCTGTTTCTGAACAAAAAACTTTCCAGGCATTTGTCAAAATTGCAGATGTTGAGATGCAGTATTATATTAATGTG >In-frame_IGFBP7_ENST00000295666_chr4_57906990_-_SPATA22_ENST00000575375_chr17_3349895_-_1005nt ATGGAGCGGCCGTCGCTGCGCGCCCTGCTCCTCGGCGCCGCTGGGCTGCTGCTCCTGCTCCTGCCCCTCTCCTCTTCCTCCTCTTCGGAC ACCTGCGGCCCCTGCGAGCCGGCCTCCTGCCCGCCCCTGCCCCCGCTGGGCTGCCTGCTGGGCGAGACCCGCGACGCGTGCGGCTGCTGC CCTATGTGCGCCCGCGGCGAGGGCGAGCCGTGCGGGGGTGGCGGCGCCGGCAGGGGGTACTGCGCGCCGGGCATGGAGTGCGTGAAGAGC CGCAAGAGGCGGAAGGGTAAAGCCGGGGCAGCAGCCGGCGGTCCGGGTGTAAGCGGCGTGTGCGTGTGCAAGAGCCGCTACCCGGTGTGC GGCAGCGACGGCACCACCTACCCGAGCGGCTGCCAGCTGCGCGCCGCCAGCCAGAGGGCCGAGAGCCGCGGGGAGAAGGCCATCACCCAG GTCAGCAAGGGCACCTGCGAGCAAGGTCCTTCCATAGTGACGCCCCCCAAGGACATCTGGAATGTCACTGGTGCCCAGGTGTACTTGAGC TGTGAGGTCATCGGAATCCCGACACCTGTCCTCATCTGGAACAAGGAAACCTCATTGTATCAGTTACAGTTTAAGGAAAAAGCTAGTTCT TTAAGAATTATTTCTGCAGTTATTGAAAGCATGAAGTATTGGCGTGAACATGCACAGAAAACTGTACTTCTTTTTGAAGTATTAGCTGTT CTTGATTCAGCTGTTACACCTGGCCCATATTATTCGAAGACTTTTCTTATGAGGGATGGGAAAAATACTCTGCCTTGTGTCTTTTATGAA ATCGATCGTGAACTTCCGAGACTGATTAGAGGCCGAGTTCATAGATGTGTTGGCAACTATGACCAGAAAAAGAACATTTTCCAATGTGTT TCTGTCAGACCGGCGTCTGTTTCTGAACAAAAAACTTTCCAGGCATTTGTCAAAATTGCAGATGTTGAGATGCAGTATTATATTAATGTG >In-frame_IGFBP7_ENST00000295666_chr4_57906990_-_SPATA22_ENST00000573128_chr17_3349895_-_1005nt ATGGAGCGGCCGTCGCTGCGCGCCCTGCTCCTCGGCGCCGCTGGGCTGCTGCTCCTGCTCCTGCCCCTCTCCTCTTCCTCCTCTTCGGAC ACCTGCGGCCCCTGCGAGCCGGCCTCCTGCCCGCCCCTGCCCCCGCTGGGCTGCCTGCTGGGCGAGACCCGCGACGCGTGCGGCTGCTGC CCTATGTGCGCCCGCGGCGAGGGCGAGCCGTGCGGGGGTGGCGGCGCCGGCAGGGGGTACTGCGCGCCGGGCATGGAGTGCGTGAAGAGC CGCAAGAGGCGGAAGGGTAAAGCCGGGGCAGCAGCCGGCGGTCCGGGTGTAAGCGGCGTGTGCGTGTGCAAGAGCCGCTACCCGGTGTGC GGCAGCGACGGCACCACCTACCCGAGCGGCTGCCAGCTGCGCGCCGCCAGCCAGAGGGCCGAGAGCCGCGGGGAGAAGGCCATCACCCAG GTCAGCAAGGGCACCTGCGAGCAAGGTCCTTCCATAGTGACGCCCCCCAAGGACATCTGGAATGTCACTGGTGCCCAGGTGTACTTGAGC TGTGAGGTCATCGGAATCCCGACACCTGTCCTCATCTGGAACAAGGAAACCTCATTGTATCAGTTACAGTTTAAGGAAAAAGCTAGTTCT TTAAGAATTATTTCTGCAGTTATTGAAAGCATGAAGTATTGGCGTGAACATGCACAGAAAACTGTACTTCTTTTTGAAGTATTAGCTGTT CTTGATTCAGCTGTTACACCTGGCCCATATTATTCGAAGACTTTTCTTATGAGGGATGGGAAAAATACTCTGCCTTGTGTCTTTTATGAA ATCGATCGTGAACTTCCGAGACTGATTAGAGGCCGAGTTCATAGATGTGTTGGCAACTATGACCAGAAAAAGAACATTTTCCAATGTGTT TCTGTCAGACCGGCGTCTGTTTCTGAACAAAAAACTTTCCAGGCATTTGTCAAAATTGCAGATGTTGAGATGCAGTATTATATTAATGTG >In-frame_IGFBP7_ENST00000295666_chr4_57906990_-_SPATA22_ENST00000268981_chr17_3349895_-_723nt ATGGAGCGGCCGTCGCTGCGCGCCCTGCTCCTCGGCGCCGCTGGGCTGCTGCTCCTGCTCCTGCCCCTCTCCTCTTCCTCCTCTTCGGAC ACCTGCGGCCCCTGCGAGCCGGCCTCCTGCCCGCCCCTGCCCCCGCTGGGCTGCCTGCTGGGCGAGACCCGCGACGCGTGCGGCTGCTGC CCTATGTGCGCCCGCGGCGAGGGCGAGCCGTGCGGGGGTGGCGGCGCCGGCAGGGGGTACTGCGCGCCGGGCATGGAGTGCGTGAAGAGC CGCAAGAGGCGGAAGGGTAAAGCCGGGGCAGCAGCCGGCGGTCCGGGTGTAAGCGGCGTGTGCGTGTGCAAGAGCCGCTACCCGGTGTGC GGCAGCGACGGCACCACCTACCCGAGCGGCTGCCAGCTGCGCGCCGCCAGCCAGAGGGCCGAGAGCCGCGGGGAGAAGGCCATCACCCAG GTCAGCAAGGGCACCTGCGAGCAAGGTCCTTCCATAGTGACGCCCCCCAAGGACATCTGGAATGTCACTGGTGCCCAGGTGTACTTGAGC TGTGAGGTCATCGGAATCCCGACACCTGTCCTCATCTGGAACAAGGAAACCTCATTGTATCAGTTACAGTTTAAGGAAAAAGCTAGTTCT TTAAGAATTATTTCTGCAGTTATTGAAAGCATGAAGTATTGGCGTGAACATGCACAGAAAACTGTACTTCTTTTTGAAGTATTAGGATCG >In-frame_IGFBP7_ENST00000537922_chr4_57906990_-_SPATA22_ENST00000541913_chr17_3349895_-_1005nt ATGGAGCGGCCGTCGCTGCGCGCCCTGCTCCTCGGCGCCGCTGGGCTGCTGCTCCTGCTCCTGCCCCTCTCCTCTTCCTCCTCTTCGGAC ACCTGCGGCCCCTGCGAGCCGGCCTCCTGCCCGCCCCTGCCCCCGCTGGGCTGCCTGCTGGGCGAGACCCGCGACGCGTGCGGCTGCTGC CCTATGTGCGCCCGCGGCGAGGGCGAGCCGTGCGGGGGTGGCGGCGCCGGCAGGGGGTACTGCGCGCCGGGCATGGAGTGCGTGAAGAGC CGCAAGAGGCGGAAGGGTAAAGCCGGGGCAGCAGCCGGCGGTCCGGGTGTAAGCGGCGTGTGCGTGTGCAAGAGCCGCTACCCGGTGTGC GGCAGCGACGGCACCACCTACCCGAGCGGCTGCCAGCTGCGCGCCGCCAGCCAGAGGGCCGAGAGCCGCGGGGAGAAGGCCATCACCCAG GTCAGCAAGGGCACCTGCGAGCAAGGTCCTTCCATAGTGACGCCCCCCAAGGACATCTGGAATGTCACTGGTGCCCAGGTGTACTTGAGC TGTGAGGTCATCGGAATCCCGACACCTGTCCTCATCTGGAACAAGGAAACCTCATTGTATCAGTTACAGTTTAAGGAAAAAGCTAGTTCT TTAAGAATTATTTCTGCAGTTATTGAAAGCATGAAGTATTGGCGTGAACATGCACAGAAAACTGTACTTCTTTTTGAAGTATTAGCTGTT CTTGATTCAGCTGTTACACCTGGCCCATATTATTCGAAGACTTTTCTTATGAGGGATGGGAAAAATACTCTGCCTTGTGTCTTTTATGAA ATCGATCGTGAACTTCCGAGACTGATTAGAGGCCGAGTTCATAGATGTGTTGGCAACTATGACCAGAAAAAGAACATTTTCCAATGTGTT TCTGTCAGACCGGCGTCTGTTTCTGAACAAAAAACTTTCCAGGCATTTGTCAAAATTGCAGATGTTGAGATGCAGTATTATATTAATGTG >In-frame_IGFBP7_ENST00000537922_chr4_57906990_-_SPATA22_ENST00000397168_chr17_3349895_-_1005nt ATGGAGCGGCCGTCGCTGCGCGCCCTGCTCCTCGGCGCCGCTGGGCTGCTGCTCCTGCTCCTGCCCCTCTCCTCTTCCTCCTCTTCGGAC ACCTGCGGCCCCTGCGAGCCGGCCTCCTGCCCGCCCCTGCCCCCGCTGGGCTGCCTGCTGGGCGAGACCCGCGACGCGTGCGGCTGCTGC CCTATGTGCGCCCGCGGCGAGGGCGAGCCGTGCGGGGGTGGCGGCGCCGGCAGGGGGTACTGCGCGCCGGGCATGGAGTGCGTGAAGAGC CGCAAGAGGCGGAAGGGTAAAGCCGGGGCAGCAGCCGGCGGTCCGGGTGTAAGCGGCGTGTGCGTGTGCAAGAGCCGCTACCCGGTGTGC GGCAGCGACGGCACCACCTACCCGAGCGGCTGCCAGCTGCGCGCCGCCAGCCAGAGGGCCGAGAGCCGCGGGGAGAAGGCCATCACCCAG GTCAGCAAGGGCACCTGCGAGCAAGGTCCTTCCATAGTGACGCCCCCCAAGGACATCTGGAATGTCACTGGTGCCCAGGTGTACTTGAGC TGTGAGGTCATCGGAATCCCGACACCTGTCCTCATCTGGAACAAGGAAACCTCATTGTATCAGTTACAGTTTAAGGAAAAAGCTAGTTCT TTAAGAATTATTTCTGCAGTTATTGAAAGCATGAAGTATTGGCGTGAACATGCACAGAAAACTGTACTTCTTTTTGAAGTATTAGCTGTT CTTGATTCAGCTGTTACACCTGGCCCATATTATTCGAAGACTTTTCTTATGAGGGATGGGAAAAATACTCTGCCTTGTGTCTTTTATGAA ATCGATCGTGAACTTCCGAGACTGATTAGAGGCCGAGTTCATAGATGTGTTGGCAACTATGACCAGAAAAAGAACATTTTCCAATGTGTT TCTGTCAGACCGGCGTCTGTTTCTGAACAAAAAACTTTCCAGGCATTTGTCAAAATTGCAGATGTTGAGATGCAGTATTATATTAATGTG >In-frame_IGFBP7_ENST00000537922_chr4_57906990_-_SPATA22_ENST00000572969_chr17_3349895_-_1005nt ATGGAGCGGCCGTCGCTGCGCGCCCTGCTCCTCGGCGCCGCTGGGCTGCTGCTCCTGCTCCTGCCCCTCTCCTCTTCCTCCTCTTCGGAC ACCTGCGGCCCCTGCGAGCCGGCCTCCTGCCCGCCCCTGCCCCCGCTGGGCTGCCTGCTGGGCGAGACCCGCGACGCGTGCGGCTGCTGC CCTATGTGCGCCCGCGGCGAGGGCGAGCCGTGCGGGGGTGGCGGCGCCGGCAGGGGGTACTGCGCGCCGGGCATGGAGTGCGTGAAGAGC CGCAAGAGGCGGAAGGGTAAAGCCGGGGCAGCAGCCGGCGGTCCGGGTGTAAGCGGCGTGTGCGTGTGCAAGAGCCGCTACCCGGTGTGC GGCAGCGACGGCACCACCTACCCGAGCGGCTGCCAGCTGCGCGCCGCCAGCCAGAGGGCCGAGAGCCGCGGGGAGAAGGCCATCACCCAG GTCAGCAAGGGCACCTGCGAGCAAGGTCCTTCCATAGTGACGCCCCCCAAGGACATCTGGAATGTCACTGGTGCCCAGGTGTACTTGAGC TGTGAGGTCATCGGAATCCCGACACCTGTCCTCATCTGGAACAAGGAAACCTCATTGTATCAGTTACAGTTTAAGGAAAAAGCTAGTTCT TTAAGAATTATTTCTGCAGTTATTGAAAGCATGAAGTATTGGCGTGAACATGCACAGAAAACTGTACTTCTTTTTGAAGTATTAGCTGTT CTTGATTCAGCTGTTACACCTGGCCCATATTATTCGAAGACTTTTCTTATGAGGGATGGGAAAAATACTCTGCCTTGTGTCTTTTATGAA ATCGATCGTGAACTTCCGAGACTGATTAGAGGCCGAGTTCATAGATGTGTTGGCAACTATGACCAGAAAAAGAACATTTTCCAATGTGTT TCTGTCAGACCGGCGTCTGTTTCTGAACAAAAAACTTTCCAGGCATTTGTCAAAATTGCAGATGTTGAGATGCAGTATTATATTAATGTG >In-frame_IGFBP7_ENST00000537922_chr4_57906990_-_SPATA22_ENST00000355380_chr17_3349895_-_1005nt ATGGAGCGGCCGTCGCTGCGCGCCCTGCTCCTCGGCGCCGCTGGGCTGCTGCTCCTGCTCCTGCCCCTCTCCTCTTCCTCCTCTTCGGAC ACCTGCGGCCCCTGCGAGCCGGCCTCCTGCCCGCCCCTGCCCCCGCTGGGCTGCCTGCTGGGCGAGACCCGCGACGCGTGCGGCTGCTGC CCTATGTGCGCCCGCGGCGAGGGCGAGCCGTGCGGGGGTGGCGGCGCCGGCAGGGGGTACTGCGCGCCGGGCATGGAGTGCGTGAAGAGC CGCAAGAGGCGGAAGGGTAAAGCCGGGGCAGCAGCCGGCGGTCCGGGTGTAAGCGGCGTGTGCGTGTGCAAGAGCCGCTACCCGGTGTGC GGCAGCGACGGCACCACCTACCCGAGCGGCTGCCAGCTGCGCGCCGCCAGCCAGAGGGCCGAGAGCCGCGGGGAGAAGGCCATCACCCAG GTCAGCAAGGGCACCTGCGAGCAAGGTCCTTCCATAGTGACGCCCCCCAAGGACATCTGGAATGTCACTGGTGCCCAGGTGTACTTGAGC TGTGAGGTCATCGGAATCCCGACACCTGTCCTCATCTGGAACAAGGAAACCTCATTGTATCAGTTACAGTTTAAGGAAAAAGCTAGTTCT TTAAGAATTATTTCTGCAGTTATTGAAAGCATGAAGTATTGGCGTGAACATGCACAGAAAACTGTACTTCTTTTTGAAGTATTAGCTGTT CTTGATTCAGCTGTTACACCTGGCCCATATTATTCGAAGACTTTTCTTATGAGGGATGGGAAAAATACTCTGCCTTGTGTCTTTTATGAA ATCGATCGTGAACTTCCGAGACTGATTAGAGGCCGAGTTCATAGATGTGTTGGCAACTATGACCAGAAAAAGAACATTTTCCAATGTGTT TCTGTCAGACCGGCGTCTGTTTCTGAACAAAAAACTTTCCAGGCATTTGTCAAAATTGCAGATGTTGAGATGCAGTATTATATTAATGTG >In-frame_IGFBP7_ENST00000537922_chr4_57906990_-_SPATA22_ENST00000575375_chr17_3349895_-_1005nt ATGGAGCGGCCGTCGCTGCGCGCCCTGCTCCTCGGCGCCGCTGGGCTGCTGCTCCTGCTCCTGCCCCTCTCCTCTTCCTCCTCTTCGGAC ACCTGCGGCCCCTGCGAGCCGGCCTCCTGCCCGCCCCTGCCCCCGCTGGGCTGCCTGCTGGGCGAGACCCGCGACGCGTGCGGCTGCTGC CCTATGTGCGCCCGCGGCGAGGGCGAGCCGTGCGGGGGTGGCGGCGCCGGCAGGGGGTACTGCGCGCCGGGCATGGAGTGCGTGAAGAGC CGCAAGAGGCGGAAGGGTAAAGCCGGGGCAGCAGCCGGCGGTCCGGGTGTAAGCGGCGTGTGCGTGTGCAAGAGCCGCTACCCGGTGTGC GGCAGCGACGGCACCACCTACCCGAGCGGCTGCCAGCTGCGCGCCGCCAGCCAGAGGGCCGAGAGCCGCGGGGAGAAGGCCATCACCCAG GTCAGCAAGGGCACCTGCGAGCAAGGTCCTTCCATAGTGACGCCCCCCAAGGACATCTGGAATGTCACTGGTGCCCAGGTGTACTTGAGC TGTGAGGTCATCGGAATCCCGACACCTGTCCTCATCTGGAACAAGGAAACCTCATTGTATCAGTTACAGTTTAAGGAAAAAGCTAGTTCT TTAAGAATTATTTCTGCAGTTATTGAAAGCATGAAGTATTGGCGTGAACATGCACAGAAAACTGTACTTCTTTTTGAAGTATTAGCTGTT CTTGATTCAGCTGTTACACCTGGCCCATATTATTCGAAGACTTTTCTTATGAGGGATGGGAAAAATACTCTGCCTTGTGTCTTTTATGAA ATCGATCGTGAACTTCCGAGACTGATTAGAGGCCGAGTTCATAGATGTGTTGGCAACTATGACCAGAAAAAGAACATTTTCCAATGTGTT TCTGTCAGACCGGCGTCTGTTTCTGAACAAAAAACTTTCCAGGCATTTGTCAAAATTGCAGATGTTGAGATGCAGTATTATATTAATGTG >In-frame_IGFBP7_ENST00000537922_chr4_57906990_-_SPATA22_ENST00000573128_chr17_3349895_-_1005nt ATGGAGCGGCCGTCGCTGCGCGCCCTGCTCCTCGGCGCCGCTGGGCTGCTGCTCCTGCTCCTGCCCCTCTCCTCTTCCTCCTCTTCGGAC ACCTGCGGCCCCTGCGAGCCGGCCTCCTGCCCGCCCCTGCCCCCGCTGGGCTGCCTGCTGGGCGAGACCCGCGACGCGTGCGGCTGCTGC CCTATGTGCGCCCGCGGCGAGGGCGAGCCGTGCGGGGGTGGCGGCGCCGGCAGGGGGTACTGCGCGCCGGGCATGGAGTGCGTGAAGAGC CGCAAGAGGCGGAAGGGTAAAGCCGGGGCAGCAGCCGGCGGTCCGGGTGTAAGCGGCGTGTGCGTGTGCAAGAGCCGCTACCCGGTGTGC GGCAGCGACGGCACCACCTACCCGAGCGGCTGCCAGCTGCGCGCCGCCAGCCAGAGGGCCGAGAGCCGCGGGGAGAAGGCCATCACCCAG GTCAGCAAGGGCACCTGCGAGCAAGGTCCTTCCATAGTGACGCCCCCCAAGGACATCTGGAATGTCACTGGTGCCCAGGTGTACTTGAGC TGTGAGGTCATCGGAATCCCGACACCTGTCCTCATCTGGAACAAGGAAACCTCATTGTATCAGTTACAGTTTAAGGAAAAAGCTAGTTCT TTAAGAATTATTTCTGCAGTTATTGAAAGCATGAAGTATTGGCGTGAACATGCACAGAAAACTGTACTTCTTTTTGAAGTATTAGCTGTT CTTGATTCAGCTGTTACACCTGGCCCATATTATTCGAAGACTTTTCTTATGAGGGATGGGAAAAATACTCTGCCTTGTGTCTTTTATGAA ATCGATCGTGAACTTCCGAGACTGATTAGAGGCCGAGTTCATAGATGTGTTGGCAACTATGACCAGAAAAAGAACATTTTCCAATGTGTT TCTGTCAGACCGGCGTCTGTTTCTGAACAAAAAACTTTCCAGGCATTTGTCAAAATTGCAGATGTTGAGATGCAGTATTATATTAATGTG >In-frame_IGFBP7_ENST00000537922_chr4_57906990_-_SPATA22_ENST00000268981_chr17_3349895_-_723nt ATGGAGCGGCCGTCGCTGCGCGCCCTGCTCCTCGGCGCCGCTGGGCTGCTGCTCCTGCTCCTGCCCCTCTCCTCTTCCTCCTCTTCGGAC ACCTGCGGCCCCTGCGAGCCGGCCTCCTGCCCGCCCCTGCCCCCGCTGGGCTGCCTGCTGGGCGAGACCCGCGACGCGTGCGGCTGCTGC CCTATGTGCGCCCGCGGCGAGGGCGAGCCGTGCGGGGGTGGCGGCGCCGGCAGGGGGTACTGCGCGCCGGGCATGGAGTGCGTGAAGAGC CGCAAGAGGCGGAAGGGTAAAGCCGGGGCAGCAGCCGGCGGTCCGGGTGTAAGCGGCGTGTGCGTGTGCAAGAGCCGCTACCCGGTGTGC GGCAGCGACGGCACCACCTACCCGAGCGGCTGCCAGCTGCGCGCCGCCAGCCAGAGGGCCGAGAGCCGCGGGGAGAAGGCCATCACCCAG GTCAGCAAGGGCACCTGCGAGCAAGGTCCTTCCATAGTGACGCCCCCCAAGGACATCTGGAATGTCACTGGTGCCCAGGTGTACTTGAGC TGTGAGGTCATCGGAATCCCGACACCTGTCCTCATCTGGAACAAGGAAACCTCATTGTATCAGTTACAGTTTAAGGAAAAAGCTAGTTCT TTAAGAATTATTTCTGCAGTTATTGAAAGCATGAAGTATTGGCGTGAACATGCACAGAAAACTGTACTTCTTTTTGAAGTATTAGGATCG |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_IGFBP7_ENST00000295666_chr4_57906990_-_SPATA22_ENST00000541913_chr17_3349895_-_1164nt ACTCGCGCCCTTGCCGCTGCCACCGCACCCCGCCATGGAGCGGCCGTCGCTGCGCGCCCTGCTCCTCGGCGCCGCTGGGCTGCTGCTCCT GCTCCTGCCCCTCTCCTCTTCCTCCTCTTCGGACACCTGCGGCCCCTGCGAGCCGGCCTCCTGCCCGCCCCTGCCCCCGCTGGGCTGCCT GCTGGGCGAGACCCGCGACGCGTGCGGCTGCTGCCCTATGTGCGCCCGCGGCGAGGGCGAGCCGTGCGGGGGTGGCGGCGCCGGCAGGGG GTACTGCGCGCCGGGCATGGAGTGCGTGAAGAGCCGCAAGAGGCGGAAGGGTAAAGCCGGGGCAGCAGCCGGCGGTCCGGGTGTAAGCGG CGTGTGCGTGTGCAAGAGCCGCTACCCGGTGTGCGGCAGCGACGGCACCACCTACCCGAGCGGCTGCCAGCTGCGCGCCGCCAGCCAGAG GGCCGAGAGCCGCGGGGAGAAGGCCATCACCCAGGTCAGCAAGGGCACCTGCGAGCAAGGTCCTTCCATAGTGACGCCCCCCAAGGACAT CTGGAATGTCACTGGTGCCCAGGTGTACTTGAGCTGTGAGGTCATCGGAATCCCGACACCTGTCCTCATCTGGAACAAGGAAACCTCATT GTATCAGTTACAGTTTAAGGAAAAAGCTAGTTCTTTAAGAATTATTTCTGCAGTTATTGAAAGCATGAAGTATTGGCGTGAACATGCACA GAAAACTGTACTTCTTTTTGAAGTATTAGCTGTTCTTGATTCAGCTGTTACACCTGGCCCATATTATTCGAAGACTTTTCTTATGAGGGA TGGGAAAAATACTCTGCCTTGTGTCTTTTATGAAATCGATCGTGAACTTCCGAGACTGATTAGAGGCCGAGTTCATAGATGTGTTGGCAA CTATGACCAGAAAAAGAACATTTTCCAATGTGTTTCTGTCAGACCGGCGTCTGTTTCTGAACAAAAAACTTTCCAGGCATTTGTCAAAAT TGCAGATGTTGAGATGCAGTATTATATTAATGTGATGAATGAAACTTAAGTAGTGATAAAAGGAAGTTTAGCATAAATTATAGCAGTTTT >In-frame_IGFBP7_ENST00000295666_chr4_57906990_-_SPATA22_ENST00000397168_chr17_3349895_-_1167nt ACTCGCGCCCTTGCCGCTGCCACCGCACCCCGCCATGGAGCGGCCGTCGCTGCGCGCCCTGCTCCTCGGCGCCGCTGGGCTGCTGCTCCT GCTCCTGCCCCTCTCCTCTTCCTCCTCTTCGGACACCTGCGGCCCCTGCGAGCCGGCCTCCTGCCCGCCCCTGCCCCCGCTGGGCTGCCT GCTGGGCGAGACCCGCGACGCGTGCGGCTGCTGCCCTATGTGCGCCCGCGGCGAGGGCGAGCCGTGCGGGGGTGGCGGCGCCGGCAGGGG GTACTGCGCGCCGGGCATGGAGTGCGTGAAGAGCCGCAAGAGGCGGAAGGGTAAAGCCGGGGCAGCAGCCGGCGGTCCGGGTGTAAGCGG CGTGTGCGTGTGCAAGAGCCGCTACCCGGTGTGCGGCAGCGACGGCACCACCTACCCGAGCGGCTGCCAGCTGCGCGCCGCCAGCCAGAG GGCCGAGAGCCGCGGGGAGAAGGCCATCACCCAGGTCAGCAAGGGCACCTGCGAGCAAGGTCCTTCCATAGTGACGCCCCCCAAGGACAT CTGGAATGTCACTGGTGCCCAGGTGTACTTGAGCTGTGAGGTCATCGGAATCCCGACACCTGTCCTCATCTGGAACAAGGAAACCTCATT GTATCAGTTACAGTTTAAGGAAAAAGCTAGTTCTTTAAGAATTATTTCTGCAGTTATTGAAAGCATGAAGTATTGGCGTGAACATGCACA GAAAACTGTACTTCTTTTTGAAGTATTAGCTGTTCTTGATTCAGCTGTTACACCTGGCCCATATTATTCGAAGACTTTTCTTATGAGGGA TGGGAAAAATACTCTGCCTTGTGTCTTTTATGAAATCGATCGTGAACTTCCGAGACTGATTAGAGGCCGAGTTCATAGATGTGTTGGCAA CTATGACCAGAAAAAGAACATTTTCCAATGTGTTTCTGTCAGACCGGCGTCTGTTTCTGAACAAAAAACTTTCCAGGCATTTGTCAAAAT TGCAGATGTTGAGATGCAGTATTATATTAATGTGATGAATGAAACTTAAGTAGTGATAAAAGGAAGTTTAGCATAAATTATAGCAGTTTT >In-frame_IGFBP7_ENST00000295666_chr4_57906990_-_SPATA22_ENST00000572969_chr17_3349895_-_1167nt ACTCGCGCCCTTGCCGCTGCCACCGCACCCCGCCATGGAGCGGCCGTCGCTGCGCGCCCTGCTCCTCGGCGCCGCTGGGCTGCTGCTCCT GCTCCTGCCCCTCTCCTCTTCCTCCTCTTCGGACACCTGCGGCCCCTGCGAGCCGGCCTCCTGCCCGCCCCTGCCCCCGCTGGGCTGCCT GCTGGGCGAGACCCGCGACGCGTGCGGCTGCTGCCCTATGTGCGCCCGCGGCGAGGGCGAGCCGTGCGGGGGTGGCGGCGCCGGCAGGGG GTACTGCGCGCCGGGCATGGAGTGCGTGAAGAGCCGCAAGAGGCGGAAGGGTAAAGCCGGGGCAGCAGCCGGCGGTCCGGGTGTAAGCGG CGTGTGCGTGTGCAAGAGCCGCTACCCGGTGTGCGGCAGCGACGGCACCACCTACCCGAGCGGCTGCCAGCTGCGCGCCGCCAGCCAGAG GGCCGAGAGCCGCGGGGAGAAGGCCATCACCCAGGTCAGCAAGGGCACCTGCGAGCAAGGTCCTTCCATAGTGACGCCCCCCAAGGACAT CTGGAATGTCACTGGTGCCCAGGTGTACTTGAGCTGTGAGGTCATCGGAATCCCGACACCTGTCCTCATCTGGAACAAGGAAACCTCATT GTATCAGTTACAGTTTAAGGAAAAAGCTAGTTCTTTAAGAATTATTTCTGCAGTTATTGAAAGCATGAAGTATTGGCGTGAACATGCACA GAAAACTGTACTTCTTTTTGAAGTATTAGCTGTTCTTGATTCAGCTGTTACACCTGGCCCATATTATTCGAAGACTTTTCTTATGAGGGA TGGGAAAAATACTCTGCCTTGTGTCTTTTATGAAATCGATCGTGAACTTCCGAGACTGATTAGAGGCCGAGTTCATAGATGTGTTGGCAA CTATGACCAGAAAAAGAACATTTTCCAATGTGTTTCTGTCAGACCGGCGTCTGTTTCTGAACAAAAAACTTTCCAGGCATTTGTCAAAAT TGCAGATGTTGAGATGCAGTATTATATTAATGTGATGAATGAAACTTAAGTAGTGATAAAAGGAAGTTTAGCATAAATTATAGCAGTTTT >In-frame_IGFBP7_ENST00000295666_chr4_57906990_-_SPATA22_ENST00000355380_chr17_3349895_-_1167nt ACTCGCGCCCTTGCCGCTGCCACCGCACCCCGCCATGGAGCGGCCGTCGCTGCGCGCCCTGCTCCTCGGCGCCGCTGGGCTGCTGCTCCT GCTCCTGCCCCTCTCCTCTTCCTCCTCTTCGGACACCTGCGGCCCCTGCGAGCCGGCCTCCTGCCCGCCCCTGCCCCCGCTGGGCTGCCT GCTGGGCGAGACCCGCGACGCGTGCGGCTGCTGCCCTATGTGCGCCCGCGGCGAGGGCGAGCCGTGCGGGGGTGGCGGCGCCGGCAGGGG GTACTGCGCGCCGGGCATGGAGTGCGTGAAGAGCCGCAAGAGGCGGAAGGGTAAAGCCGGGGCAGCAGCCGGCGGTCCGGGTGTAAGCGG CGTGTGCGTGTGCAAGAGCCGCTACCCGGTGTGCGGCAGCGACGGCACCACCTACCCGAGCGGCTGCCAGCTGCGCGCCGCCAGCCAGAG GGCCGAGAGCCGCGGGGAGAAGGCCATCACCCAGGTCAGCAAGGGCACCTGCGAGCAAGGTCCTTCCATAGTGACGCCCCCCAAGGACAT CTGGAATGTCACTGGTGCCCAGGTGTACTTGAGCTGTGAGGTCATCGGAATCCCGACACCTGTCCTCATCTGGAACAAGGAAACCTCATT GTATCAGTTACAGTTTAAGGAAAAAGCTAGTTCTTTAAGAATTATTTCTGCAGTTATTGAAAGCATGAAGTATTGGCGTGAACATGCACA GAAAACTGTACTTCTTTTTGAAGTATTAGCTGTTCTTGATTCAGCTGTTACACCTGGCCCATATTATTCGAAGACTTTTCTTATGAGGGA TGGGAAAAATACTCTGCCTTGTGTCTTTTATGAAATCGATCGTGAACTTCCGAGACTGATTAGAGGCCGAGTTCATAGATGTGTTGGCAA CTATGACCAGAAAAAGAACATTTTCCAATGTGTTTCTGTCAGACCGGCGTCTGTTTCTGAACAAAAAACTTTCCAGGCATTTGTCAAAAT TGCAGATGTTGAGATGCAGTATTATATTAATGTGATGAATGAAACTTAAGTAGTGATAAAAGGAAGTTTAGCATAAATTATAGCAGTTTT >In-frame_IGFBP7_ENST00000295666_chr4_57906990_-_SPATA22_ENST00000575375_chr17_3349895_-_1167nt ACTCGCGCCCTTGCCGCTGCCACCGCACCCCGCCATGGAGCGGCCGTCGCTGCGCGCCCTGCTCCTCGGCGCCGCTGGGCTGCTGCTCCT GCTCCTGCCCCTCTCCTCTTCCTCCTCTTCGGACACCTGCGGCCCCTGCGAGCCGGCCTCCTGCCCGCCCCTGCCCCCGCTGGGCTGCCT GCTGGGCGAGACCCGCGACGCGTGCGGCTGCTGCCCTATGTGCGCCCGCGGCGAGGGCGAGCCGTGCGGGGGTGGCGGCGCCGGCAGGGG GTACTGCGCGCCGGGCATGGAGTGCGTGAAGAGCCGCAAGAGGCGGAAGGGTAAAGCCGGGGCAGCAGCCGGCGGTCCGGGTGTAAGCGG CGTGTGCGTGTGCAAGAGCCGCTACCCGGTGTGCGGCAGCGACGGCACCACCTACCCGAGCGGCTGCCAGCTGCGCGCCGCCAGCCAGAG GGCCGAGAGCCGCGGGGAGAAGGCCATCACCCAGGTCAGCAAGGGCACCTGCGAGCAAGGTCCTTCCATAGTGACGCCCCCCAAGGACAT CTGGAATGTCACTGGTGCCCAGGTGTACTTGAGCTGTGAGGTCATCGGAATCCCGACACCTGTCCTCATCTGGAACAAGGAAACCTCATT GTATCAGTTACAGTTTAAGGAAAAAGCTAGTTCTTTAAGAATTATTTCTGCAGTTATTGAAAGCATGAAGTATTGGCGTGAACATGCACA GAAAACTGTACTTCTTTTTGAAGTATTAGCTGTTCTTGATTCAGCTGTTACACCTGGCCCATATTATTCGAAGACTTTTCTTATGAGGGA TGGGAAAAATACTCTGCCTTGTGTCTTTTATGAAATCGATCGTGAACTTCCGAGACTGATTAGAGGCCGAGTTCATAGATGTGTTGGCAA CTATGACCAGAAAAAGAACATTTTCCAATGTGTTTCTGTCAGACCGGCGTCTGTTTCTGAACAAAAAACTTTCCAGGCATTTGTCAAAAT TGCAGATGTTGAGATGCAGTATTATATTAATGTGATGAATGAAACTTAAGTAGTGATAAAAGGAAGTTTAGCATAAATTATAGCAGTTTT >In-frame_IGFBP7_ENST00000295666_chr4_57906990_-_SPATA22_ENST00000573128_chr17_3349895_-_1167nt ACTCGCGCCCTTGCCGCTGCCACCGCACCCCGCCATGGAGCGGCCGTCGCTGCGCGCCCTGCTCCTCGGCGCCGCTGGGCTGCTGCTCCT GCTCCTGCCCCTCTCCTCTTCCTCCTCTTCGGACACCTGCGGCCCCTGCGAGCCGGCCTCCTGCCCGCCCCTGCCCCCGCTGGGCTGCCT GCTGGGCGAGACCCGCGACGCGTGCGGCTGCTGCCCTATGTGCGCCCGCGGCGAGGGCGAGCCGTGCGGGGGTGGCGGCGCCGGCAGGGG GTACTGCGCGCCGGGCATGGAGTGCGTGAAGAGCCGCAAGAGGCGGAAGGGTAAAGCCGGGGCAGCAGCCGGCGGTCCGGGTGTAAGCGG CGTGTGCGTGTGCAAGAGCCGCTACCCGGTGTGCGGCAGCGACGGCACCACCTACCCGAGCGGCTGCCAGCTGCGCGCCGCCAGCCAGAG GGCCGAGAGCCGCGGGGAGAAGGCCATCACCCAGGTCAGCAAGGGCACCTGCGAGCAAGGTCCTTCCATAGTGACGCCCCCCAAGGACAT CTGGAATGTCACTGGTGCCCAGGTGTACTTGAGCTGTGAGGTCATCGGAATCCCGACACCTGTCCTCATCTGGAACAAGGAAACCTCATT GTATCAGTTACAGTTTAAGGAAAAAGCTAGTTCTTTAAGAATTATTTCTGCAGTTATTGAAAGCATGAAGTATTGGCGTGAACATGCACA GAAAACTGTACTTCTTTTTGAAGTATTAGCTGTTCTTGATTCAGCTGTTACACCTGGCCCATATTATTCGAAGACTTTTCTTATGAGGGA TGGGAAAAATACTCTGCCTTGTGTCTTTTATGAAATCGATCGTGAACTTCCGAGACTGATTAGAGGCCGAGTTCATAGATGTGTTGGCAA CTATGACCAGAAAAAGAACATTTTCCAATGTGTTTCTGTCAGACCGGCGTCTGTTTCTGAACAAAAAACTTTCCAGGCATTTGTCAAAAT TGCAGATGTTGAGATGCAGTATTATATTAATGTGATGAATGAAACTTAAGTAGTGATAAAAGGAAGTTTAGCATAAATTATAGCAGTTTT >In-frame_IGFBP7_ENST00000295666_chr4_57906990_-_SPATA22_ENST00000268981_chr17_3349895_-_845nt ACTCGCGCCCTTGCCGCTGCCACCGCACCCCGCCATGGAGCGGCCGTCGCTGCGCGCCCTGCTCCTCGGCGCCGCTGGGCTGCTGCTCCT GCTCCTGCCCCTCTCCTCTTCCTCCTCTTCGGACACCTGCGGCCCCTGCGAGCCGGCCTCCTGCCCGCCCCTGCCCCCGCTGGGCTGCCT GCTGGGCGAGACCCGCGACGCGTGCGGCTGCTGCCCTATGTGCGCCCGCGGCGAGGGCGAGCCGTGCGGGGGTGGCGGCGCCGGCAGGGG GTACTGCGCGCCGGGCATGGAGTGCGTGAAGAGCCGCAAGAGGCGGAAGGGTAAAGCCGGGGCAGCAGCCGGCGGTCCGGGTGTAAGCGG CGTGTGCGTGTGCAAGAGCCGCTACCCGGTGTGCGGCAGCGACGGCACCACCTACCCGAGCGGCTGCCAGCTGCGCGCCGCCAGCCAGAG GGCCGAGAGCCGCGGGGAGAAGGCCATCACCCAGGTCAGCAAGGGCACCTGCGAGCAAGGTCCTTCCATAGTGACGCCCCCCAAGGACAT CTGGAATGTCACTGGTGCCCAGGTGTACTTGAGCTGTGAGGTCATCGGAATCCCGACACCTGTCCTCATCTGGAACAAGGAAACCTCATT GTATCAGTTACAGTTTAAGGAAAAAGCTAGTTCTTTAAGAATTATTTCTGCAGTTATTGAAAGCATGAAGTATTGGCGTGAACATGCACA GAAAACTGTACTTCTTTTTGAAGTATTAGGATCGTGAACTTCCGAGACTGATTAGAGGCCGAGTTCATAGATGTGTTGGCAACTATGACC >In-frame_IGFBP7_ENST00000537922_chr4_57906990_-_SPATA22_ENST00000541913_chr17_3349895_-_1164nt ACTCGCGCCCTTGCCGCTGCCACCGCACCCCGCCATGGAGCGGCCGTCGCTGCGCGCCCTGCTCCTCGGCGCCGCTGGGCTGCTGCTCCT GCTCCTGCCCCTCTCCTCTTCCTCCTCTTCGGACACCTGCGGCCCCTGCGAGCCGGCCTCCTGCCCGCCCCTGCCCCCGCTGGGCTGCCT GCTGGGCGAGACCCGCGACGCGTGCGGCTGCTGCCCTATGTGCGCCCGCGGCGAGGGCGAGCCGTGCGGGGGTGGCGGCGCCGGCAGGGG GTACTGCGCGCCGGGCATGGAGTGCGTGAAGAGCCGCAAGAGGCGGAAGGGTAAAGCCGGGGCAGCAGCCGGCGGTCCGGGTGTAAGCGG CGTGTGCGTGTGCAAGAGCCGCTACCCGGTGTGCGGCAGCGACGGCACCACCTACCCGAGCGGCTGCCAGCTGCGCGCCGCCAGCCAGAG GGCCGAGAGCCGCGGGGAGAAGGCCATCACCCAGGTCAGCAAGGGCACCTGCGAGCAAGGTCCTTCCATAGTGACGCCCCCCAAGGACAT CTGGAATGTCACTGGTGCCCAGGTGTACTTGAGCTGTGAGGTCATCGGAATCCCGACACCTGTCCTCATCTGGAACAAGGAAACCTCATT GTATCAGTTACAGTTTAAGGAAAAAGCTAGTTCTTTAAGAATTATTTCTGCAGTTATTGAAAGCATGAAGTATTGGCGTGAACATGCACA GAAAACTGTACTTCTTTTTGAAGTATTAGCTGTTCTTGATTCAGCTGTTACACCTGGCCCATATTATTCGAAGACTTTTCTTATGAGGGA TGGGAAAAATACTCTGCCTTGTGTCTTTTATGAAATCGATCGTGAACTTCCGAGACTGATTAGAGGCCGAGTTCATAGATGTGTTGGCAA CTATGACCAGAAAAAGAACATTTTCCAATGTGTTTCTGTCAGACCGGCGTCTGTTTCTGAACAAAAAACTTTCCAGGCATTTGTCAAAAT TGCAGATGTTGAGATGCAGTATTATATTAATGTGATGAATGAAACTTAAGTAGTGATAAAAGGAAGTTTAGCATAAATTATAGCAGTTTT >In-frame_IGFBP7_ENST00000537922_chr4_57906990_-_SPATA22_ENST00000397168_chr17_3349895_-_1167nt ACTCGCGCCCTTGCCGCTGCCACCGCACCCCGCCATGGAGCGGCCGTCGCTGCGCGCCCTGCTCCTCGGCGCCGCTGGGCTGCTGCTCCT GCTCCTGCCCCTCTCCTCTTCCTCCTCTTCGGACACCTGCGGCCCCTGCGAGCCGGCCTCCTGCCCGCCCCTGCCCCCGCTGGGCTGCCT GCTGGGCGAGACCCGCGACGCGTGCGGCTGCTGCCCTATGTGCGCCCGCGGCGAGGGCGAGCCGTGCGGGGGTGGCGGCGCCGGCAGGGG GTACTGCGCGCCGGGCATGGAGTGCGTGAAGAGCCGCAAGAGGCGGAAGGGTAAAGCCGGGGCAGCAGCCGGCGGTCCGGGTGTAAGCGG CGTGTGCGTGTGCAAGAGCCGCTACCCGGTGTGCGGCAGCGACGGCACCACCTACCCGAGCGGCTGCCAGCTGCGCGCCGCCAGCCAGAG GGCCGAGAGCCGCGGGGAGAAGGCCATCACCCAGGTCAGCAAGGGCACCTGCGAGCAAGGTCCTTCCATAGTGACGCCCCCCAAGGACAT CTGGAATGTCACTGGTGCCCAGGTGTACTTGAGCTGTGAGGTCATCGGAATCCCGACACCTGTCCTCATCTGGAACAAGGAAACCTCATT GTATCAGTTACAGTTTAAGGAAAAAGCTAGTTCTTTAAGAATTATTTCTGCAGTTATTGAAAGCATGAAGTATTGGCGTGAACATGCACA GAAAACTGTACTTCTTTTTGAAGTATTAGCTGTTCTTGATTCAGCTGTTACACCTGGCCCATATTATTCGAAGACTTTTCTTATGAGGGA TGGGAAAAATACTCTGCCTTGTGTCTTTTATGAAATCGATCGTGAACTTCCGAGACTGATTAGAGGCCGAGTTCATAGATGTGTTGGCAA CTATGACCAGAAAAAGAACATTTTCCAATGTGTTTCTGTCAGACCGGCGTCTGTTTCTGAACAAAAAACTTTCCAGGCATTTGTCAAAAT TGCAGATGTTGAGATGCAGTATTATATTAATGTGATGAATGAAACTTAAGTAGTGATAAAAGGAAGTTTAGCATAAATTATAGCAGTTTT >In-frame_IGFBP7_ENST00000537922_chr4_57906990_-_SPATA22_ENST00000572969_chr17_3349895_-_1167nt ACTCGCGCCCTTGCCGCTGCCACCGCACCCCGCCATGGAGCGGCCGTCGCTGCGCGCCCTGCTCCTCGGCGCCGCTGGGCTGCTGCTCCT GCTCCTGCCCCTCTCCTCTTCCTCCTCTTCGGACACCTGCGGCCCCTGCGAGCCGGCCTCCTGCCCGCCCCTGCCCCCGCTGGGCTGCCT GCTGGGCGAGACCCGCGACGCGTGCGGCTGCTGCCCTATGTGCGCCCGCGGCGAGGGCGAGCCGTGCGGGGGTGGCGGCGCCGGCAGGGG GTACTGCGCGCCGGGCATGGAGTGCGTGAAGAGCCGCAAGAGGCGGAAGGGTAAAGCCGGGGCAGCAGCCGGCGGTCCGGGTGTAAGCGG CGTGTGCGTGTGCAAGAGCCGCTACCCGGTGTGCGGCAGCGACGGCACCACCTACCCGAGCGGCTGCCAGCTGCGCGCCGCCAGCCAGAG GGCCGAGAGCCGCGGGGAGAAGGCCATCACCCAGGTCAGCAAGGGCACCTGCGAGCAAGGTCCTTCCATAGTGACGCCCCCCAAGGACAT CTGGAATGTCACTGGTGCCCAGGTGTACTTGAGCTGTGAGGTCATCGGAATCCCGACACCTGTCCTCATCTGGAACAAGGAAACCTCATT GTATCAGTTACAGTTTAAGGAAAAAGCTAGTTCTTTAAGAATTATTTCTGCAGTTATTGAAAGCATGAAGTATTGGCGTGAACATGCACA GAAAACTGTACTTCTTTTTGAAGTATTAGCTGTTCTTGATTCAGCTGTTACACCTGGCCCATATTATTCGAAGACTTTTCTTATGAGGGA TGGGAAAAATACTCTGCCTTGTGTCTTTTATGAAATCGATCGTGAACTTCCGAGACTGATTAGAGGCCGAGTTCATAGATGTGTTGGCAA CTATGACCAGAAAAAGAACATTTTCCAATGTGTTTCTGTCAGACCGGCGTCTGTTTCTGAACAAAAAACTTTCCAGGCATTTGTCAAAAT TGCAGATGTTGAGATGCAGTATTATATTAATGTGATGAATGAAACTTAAGTAGTGATAAAAGGAAGTTTAGCATAAATTATAGCAGTTTT >In-frame_IGFBP7_ENST00000537922_chr4_57906990_-_SPATA22_ENST00000355380_chr17_3349895_-_1167nt ACTCGCGCCCTTGCCGCTGCCACCGCACCCCGCCATGGAGCGGCCGTCGCTGCGCGCCCTGCTCCTCGGCGCCGCTGGGCTGCTGCTCCT GCTCCTGCCCCTCTCCTCTTCCTCCTCTTCGGACACCTGCGGCCCCTGCGAGCCGGCCTCCTGCCCGCCCCTGCCCCCGCTGGGCTGCCT GCTGGGCGAGACCCGCGACGCGTGCGGCTGCTGCCCTATGTGCGCCCGCGGCGAGGGCGAGCCGTGCGGGGGTGGCGGCGCCGGCAGGGG GTACTGCGCGCCGGGCATGGAGTGCGTGAAGAGCCGCAAGAGGCGGAAGGGTAAAGCCGGGGCAGCAGCCGGCGGTCCGGGTGTAAGCGG CGTGTGCGTGTGCAAGAGCCGCTACCCGGTGTGCGGCAGCGACGGCACCACCTACCCGAGCGGCTGCCAGCTGCGCGCCGCCAGCCAGAG GGCCGAGAGCCGCGGGGAGAAGGCCATCACCCAGGTCAGCAAGGGCACCTGCGAGCAAGGTCCTTCCATAGTGACGCCCCCCAAGGACAT CTGGAATGTCACTGGTGCCCAGGTGTACTTGAGCTGTGAGGTCATCGGAATCCCGACACCTGTCCTCATCTGGAACAAGGAAACCTCATT GTATCAGTTACAGTTTAAGGAAAAAGCTAGTTCTTTAAGAATTATTTCTGCAGTTATTGAAAGCATGAAGTATTGGCGTGAACATGCACA GAAAACTGTACTTCTTTTTGAAGTATTAGCTGTTCTTGATTCAGCTGTTACACCTGGCCCATATTATTCGAAGACTTTTCTTATGAGGGA TGGGAAAAATACTCTGCCTTGTGTCTTTTATGAAATCGATCGTGAACTTCCGAGACTGATTAGAGGCCGAGTTCATAGATGTGTTGGCAA CTATGACCAGAAAAAGAACATTTTCCAATGTGTTTCTGTCAGACCGGCGTCTGTTTCTGAACAAAAAACTTTCCAGGCATTTGTCAAAAT TGCAGATGTTGAGATGCAGTATTATATTAATGTGATGAATGAAACTTAAGTAGTGATAAAAGGAAGTTTAGCATAAATTATAGCAGTTTT >In-frame_IGFBP7_ENST00000537922_chr4_57906990_-_SPATA22_ENST00000575375_chr17_3349895_-_1167nt ACTCGCGCCCTTGCCGCTGCCACCGCACCCCGCCATGGAGCGGCCGTCGCTGCGCGCCCTGCTCCTCGGCGCCGCTGGGCTGCTGCTCCT GCTCCTGCCCCTCTCCTCTTCCTCCTCTTCGGACACCTGCGGCCCCTGCGAGCCGGCCTCCTGCCCGCCCCTGCCCCCGCTGGGCTGCCT GCTGGGCGAGACCCGCGACGCGTGCGGCTGCTGCCCTATGTGCGCCCGCGGCGAGGGCGAGCCGTGCGGGGGTGGCGGCGCCGGCAGGGG GTACTGCGCGCCGGGCATGGAGTGCGTGAAGAGCCGCAAGAGGCGGAAGGGTAAAGCCGGGGCAGCAGCCGGCGGTCCGGGTGTAAGCGG CGTGTGCGTGTGCAAGAGCCGCTACCCGGTGTGCGGCAGCGACGGCACCACCTACCCGAGCGGCTGCCAGCTGCGCGCCGCCAGCCAGAG GGCCGAGAGCCGCGGGGAGAAGGCCATCACCCAGGTCAGCAAGGGCACCTGCGAGCAAGGTCCTTCCATAGTGACGCCCCCCAAGGACAT CTGGAATGTCACTGGTGCCCAGGTGTACTTGAGCTGTGAGGTCATCGGAATCCCGACACCTGTCCTCATCTGGAACAAGGAAACCTCATT GTATCAGTTACAGTTTAAGGAAAAAGCTAGTTCTTTAAGAATTATTTCTGCAGTTATTGAAAGCATGAAGTATTGGCGTGAACATGCACA GAAAACTGTACTTCTTTTTGAAGTATTAGCTGTTCTTGATTCAGCTGTTACACCTGGCCCATATTATTCGAAGACTTTTCTTATGAGGGA TGGGAAAAATACTCTGCCTTGTGTCTTTTATGAAATCGATCGTGAACTTCCGAGACTGATTAGAGGCCGAGTTCATAGATGTGTTGGCAA CTATGACCAGAAAAAGAACATTTTCCAATGTGTTTCTGTCAGACCGGCGTCTGTTTCTGAACAAAAAACTTTCCAGGCATTTGTCAAAAT TGCAGATGTTGAGATGCAGTATTATATTAATGTGATGAATGAAACTTAAGTAGTGATAAAAGGAAGTTTAGCATAAATTATAGCAGTTTT >In-frame_IGFBP7_ENST00000537922_chr4_57906990_-_SPATA22_ENST00000573128_chr17_3349895_-_1167nt ACTCGCGCCCTTGCCGCTGCCACCGCACCCCGCCATGGAGCGGCCGTCGCTGCGCGCCCTGCTCCTCGGCGCCGCTGGGCTGCTGCTCCT GCTCCTGCCCCTCTCCTCTTCCTCCTCTTCGGACACCTGCGGCCCCTGCGAGCCGGCCTCCTGCCCGCCCCTGCCCCCGCTGGGCTGCCT GCTGGGCGAGACCCGCGACGCGTGCGGCTGCTGCCCTATGTGCGCCCGCGGCGAGGGCGAGCCGTGCGGGGGTGGCGGCGCCGGCAGGGG GTACTGCGCGCCGGGCATGGAGTGCGTGAAGAGCCGCAAGAGGCGGAAGGGTAAAGCCGGGGCAGCAGCCGGCGGTCCGGGTGTAAGCGG CGTGTGCGTGTGCAAGAGCCGCTACCCGGTGTGCGGCAGCGACGGCACCACCTACCCGAGCGGCTGCCAGCTGCGCGCCGCCAGCCAGAG GGCCGAGAGCCGCGGGGAGAAGGCCATCACCCAGGTCAGCAAGGGCACCTGCGAGCAAGGTCCTTCCATAGTGACGCCCCCCAAGGACAT CTGGAATGTCACTGGTGCCCAGGTGTACTTGAGCTGTGAGGTCATCGGAATCCCGACACCTGTCCTCATCTGGAACAAGGAAACCTCATT GTATCAGTTACAGTTTAAGGAAAAAGCTAGTTCTTTAAGAATTATTTCTGCAGTTATTGAAAGCATGAAGTATTGGCGTGAACATGCACA GAAAACTGTACTTCTTTTTGAAGTATTAGCTGTTCTTGATTCAGCTGTTACACCTGGCCCATATTATTCGAAGACTTTTCTTATGAGGGA TGGGAAAAATACTCTGCCTTGTGTCTTTTATGAAATCGATCGTGAACTTCCGAGACTGATTAGAGGCCGAGTTCATAGATGTGTTGGCAA CTATGACCAGAAAAAGAACATTTTCCAATGTGTTTCTGTCAGACCGGCGTCTGTTTCTGAACAAAAAACTTTCCAGGCATTTGTCAAAAT TGCAGATGTTGAGATGCAGTATTATATTAATGTGATGAATGAAACTTAAGTAGTGATAAAAGGAAGTTTAGCATAAATTATAGCAGTTTT >In-frame_IGFBP7_ENST00000537922_chr4_57906990_-_SPATA22_ENST00000268981_chr17_3349895_-_845nt ACTCGCGCCCTTGCCGCTGCCACCGCACCCCGCCATGGAGCGGCCGTCGCTGCGCGCCCTGCTCCTCGGCGCCGCTGGGCTGCTGCTCCT GCTCCTGCCCCTCTCCTCTTCCTCCTCTTCGGACACCTGCGGCCCCTGCGAGCCGGCCTCCTGCCCGCCCCTGCCCCCGCTGGGCTGCCT GCTGGGCGAGACCCGCGACGCGTGCGGCTGCTGCCCTATGTGCGCCCGCGGCGAGGGCGAGCCGTGCGGGGGTGGCGGCGCCGGCAGGGG GTACTGCGCGCCGGGCATGGAGTGCGTGAAGAGCCGCAAGAGGCGGAAGGGTAAAGCCGGGGCAGCAGCCGGCGGTCCGGGTGTAAGCGG CGTGTGCGTGTGCAAGAGCCGCTACCCGGTGTGCGGCAGCGACGGCACCACCTACCCGAGCGGCTGCCAGCTGCGCGCCGCCAGCCAGAG GGCCGAGAGCCGCGGGGAGAAGGCCATCACCCAGGTCAGCAAGGGCACCTGCGAGCAAGGTCCTTCCATAGTGACGCCCCCCAAGGACAT CTGGAATGTCACTGGTGCCCAGGTGTACTTGAGCTGTGAGGTCATCGGAATCCCGACACCTGTCCTCATCTGGAACAAGGAAACCTCATT GTATCAGTTACAGTTTAAGGAAAAAGCTAGTTCTTTAAGAATTATTTCTGCAGTTATTGAAAGCATGAAGTATTGGCGTGAACATGCACA GAAAACTGTACTTCTTTTTGAAGTATTAGGATCGTGAACTTCCGAGACTGATTAGAGGCCGAGTTCATAGATGTGTTGGCAACTATGACC |
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FusionGenePPI for IGFBP7_SPATA22 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| IGFBP7 | IGF1, IGF2, CHMP3, VEGFA, INS, DSTN, RTN4, HNF1A, RBBP8, YAP1 | SPATA22 | ECT2, KDM1A, PRMT6, GOLGA2, DES, ACTA2, ACTBL2, FAM107A |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for IGFBP7_SPATA22 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
| Hgene | IGFBP7 | Q16270 | DB00071 | Insulin Pork | Insulin-like growth factor-binding protein 7 | biotech | approved |
| Hgene | IGFBP7 | Q16270 | DB00030 | Insulin Human | Insulin-like growth factor-binding protein 7 | biotech | approved|investigational |
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RelatedDiseases for IGFBP7_SPATA22 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | IGFBP7 | C0001973 | Alcoholic Intoxication, Chronic | 1 | PSYGENET |
| Hgene | IGFBP7 | C0023893 | Liver Cirrhosis, Experimental | 1 | CTD_human |
| Hgene | IGFBP7 | C0033578 | Prostatic Neoplasms | 1 | CTD_human |
| Hgene | IGFBP7 | C0038356 | Stomach Neoplasms | 1 | CTD_human |
| Hgene | IGFBP7 | C1458155 | Mammary Neoplasms | 1 | CTD_human |
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