![]() |
||||||
|
![]() | |
![]() | |
![]() | |
![]() | |
![]() | |
![]() |
Fusion gene ID: 17068 |
FusionGeneSummary for IFI6_TNRC18 |
![]() |
Fusion gene information | Fusion gene name: IFI6_TNRC18 | Fusion gene ID: 17068 | Hgene | Tgene | Gene symbol | IFI6 | TNRC18 | Gene ID | 2537 | 84629 |
Gene name | interferon alpha inducible protein 6 | trinucleotide repeat containing 18 | |
Synonyms | 6-16|FAM14C|G1P3|IFI-6-16|IFI616 | CAGL79|TNRC18A | |
Cytomap | 1p35.3 | 7p22.1 | |
Type of gene | protein-coding | protein-coding | |
Description | interferon alpha-inducible protein 6interferon, alpha-inducible protein clone IFI-6-16interferon-induced protein 6-16 | trinucleotide repeat-containing gene 18 proteinlong CAG trinucleotide repeat-containing gene 79 protein | |
Modification date | 20180523 | 20180522 | |
UniProtAcc | P09912 | O15417 | |
Ensembl transtripts involved in fusion gene | ENST00000361157, ENST00000339145, ENST00000362020, | ENST00000399537, ENST00000430969, ENST00000399434, | |
Fusion gene scores | * DoF score | 6 X 5 X 2=60 | 8 X 9 X 1=72 |
# samples | 6 | 10 | |
** MAII score | log2(6/60*10)=0 | log2(10/72*10)=0.473931188332412 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
Context | PubMed: IFI6 [Title/Abstract] AND TNRC18 [Title/Abstract] AND fusion [Title/Abstract] | ||
Functional or gene categories assigned by FusionGDB annotation |
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
![]() |
Partner | Gene | GO ID | GO term | PubMed ID |
![]() (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
ChiTaRS3.1 | BP320632 | IFI6 | chr1 | 27994791 | - | TNRC18 | chr7 | 5413712 | - |
* LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
![]() * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
intron-3CDS | ENST00000361157 | ENST00000399537 | IFI6 | chr1 | 27994791 | - | TNRC18 | chr7 | 5413712 | - |
intron-3CDS | ENST00000361157 | ENST00000430969 | IFI6 | chr1 | 27994791 | - | TNRC18 | chr7 | 5413712 | - |
intron-intron | ENST00000361157 | ENST00000399434 | IFI6 | chr1 | 27994791 | - | TNRC18 | chr7 | 5413712 | - |
intron-3CDS | ENST00000339145 | ENST00000399537 | IFI6 | chr1 | 27994791 | - | TNRC18 | chr7 | 5413712 | - |
intron-3CDS | ENST00000339145 | ENST00000430969 | IFI6 | chr1 | 27994791 | - | TNRC18 | chr7 | 5413712 | - |
intron-intron | ENST00000339145 | ENST00000399434 | IFI6 | chr1 | 27994791 | - | TNRC18 | chr7 | 5413712 | - |
intron-3CDS | ENST00000362020 | ENST00000399537 | IFI6 | chr1 | 27994791 | - | TNRC18 | chr7 | 5413712 | - |
intron-3CDS | ENST00000362020 | ENST00000430969 | IFI6 | chr1 | 27994791 | - | TNRC18 | chr7 | 5413712 | - |
intron-intron | ENST00000362020 | ENST00000399434 | IFI6 | chr1 | 27994791 | - | TNRC18 | chr7 | 5413712 | - |
Top |
FusionProtFeatures for IFI6_TNRC18 |
![]() |
Hgene | Tgene |
IFI6 | TNRC18 |
![]() * Minus value of BPloci means that the break pointn is located before the CDS. |
- In-frame and retained protein feature among the 13 regional features. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
- In-frame and not-retained protein feature among the 13 regional features. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
Top |
FusionGeneSequence for IFI6_TNRC18 |
![]() (nt: nucleotides, aa: amino acids) |
* Fusion amino acid sequences. |
* Fusion transcript sequences (only coding sequence (CDS) region). |
* Fusion transcript sequences (Full-length transcript). |
Top |
FusionGenePPI for IFI6_TNRC18 |
![]() |
![]() |
Hgene | Hgene's interactors | Tgene | Tgene's interactors |
![]() |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
![]() |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
![]() |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
Top |
RelatedDrugs for IFI6_TNRC18 |
![]() (DrugBank Version 5.1.0 2018-04-02) |
Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
Top |
RelatedDiseases for IFI6_TNRC18 |
![]() (DisGeNet 4.0) |
Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
Hgene | IFI6 | C0000786 | Spontaneous abortion | 1 | CTD_human |
Hgene | IFI6 | C0021400 | Influenza | 1 | CTD_human |