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Fusion gene ID: 16953 |
FusionGeneSummary for HTT_WDR19 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: HTT_WDR19 | Fusion gene ID: 16953 | Hgene | Tgene | Gene symbol | HTT | WDR19 | Gene ID | 6532 | 57728 |
| Gene name | solute carrier family 6 member 4 | WD repeat domain 19 | |
| Synonyms | 5-HTT|5-HTTLPR|5HTT|HTT|OCD1|SERT|SERT1|hSERT | ATD5|CED4|DYF-2|IFT144|NPHP13|ORF26|Oseg6|PWDMP|SRTD5 | |
| Cytomap | 17q11.2 | 4p14 | |
| Type of gene | protein-coding | protein-coding | |
| Description | sodium-dependent serotonin transporter5-hydroxytryptamine (serotonin) transporter5HT transporterNa+/Cl- dependent serotonin transporterserotonin transporter 1solute carrier family 6 (neurotransmitter transporter), member 4solute carrier family 6 (ne | WD repeat-containing protein 19WD repeat membrane protein PWDMPintraflagellar transport 144 homolog | |
| Modification date | 20180527 | 20180523 | |
| UniProtAcc | P42858 | Q8NEZ3 | |
| Ensembl transtripts involved in fusion gene | ENST00000355072, ENST00000513806, | ENST00000399820, ENST00000288634, ENST00000506503, ENST00000515631, | |
| Fusion gene scores | * DoF score | 8 X 12 X 8=768 | 4 X 4 X 4=64 |
| # samples | 12 | 4 | |
| ** MAII score | log2(12/768*10)=-2.67807190511264 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(4/64*10)=-0.678071905112638 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: HTT [Title/Abstract] AND WDR19 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | HTT | GO:0006837 | serotonin transport | 19270731 |
| Hgene | HTT | GO:0009636 | response to toxic substance | 17575980 |
| Hgene | HTT | GO:0015844 | monoamine transport | 16024787 |
| Hgene | HTT | GO:0051610 | serotonin uptake | 8987735|16870614|17506858|18227069|19270731 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | PRAD | TCGA-V1-A9OL-01A | HTT | chr4 | 3190820 | + | WDR19 | chr4 | 39257468 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000355072 | ENST00000399820 | HTT | chr4 | 3190820 | + | WDR19 | chr4 | 39257468 | + |
| In-frame | ENST00000355072 | ENST00000288634 | HTT | chr4 | 3190820 | + | WDR19 | chr4 | 39257468 | + |
| 5CDS-intron | ENST00000355072 | ENST00000506503 | HTT | chr4 | 3190820 | + | WDR19 | chr4 | 39257468 | + |
| 5CDS-intron | ENST00000355072 | ENST00000515631 | HTT | chr4 | 3190820 | + | WDR19 | chr4 | 39257468 | + |
| intron-3CDS | ENST00000513806 | ENST00000399820 | HTT | chr4 | 3190820 | + | WDR19 | chr4 | 39257468 | + |
| intron-3CDS | ENST00000513806 | ENST00000288634 | HTT | chr4 | 3190820 | + | WDR19 | chr4 | 39257468 | + |
| intron-intron | ENST00000513806 | ENST00000506503 | HTT | chr4 | 3190820 | + | WDR19 | chr4 | 39257468 | + |
| intron-intron | ENST00000513806 | ENST00000515631 | HTT | chr4 | 3190820 | + | WDR19 | chr4 | 39257468 | + |
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FusionProtFeatures for HTT_WDR19 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| HTT | WDR19 |
| May play a role in microtubule-mediated transport orvesicle function. | Component of the IFT complex A (IFT-A), a complexrequired for retrograde ciliary transport (PubMed:20889716).Involved in cilia function and/or assembly (By similarity).Associates with the BBSome complex to mediate ciliary transport(By similarity). {ECO:0000250|UniProtKB:Q3UGF1,ECO:0000269|PubMed:20889716}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | HTT | chr4:3190820 | chr4:39257468 | ENST00000355072 | + | 40 | 67 | 1437_1440 | 1789 | 3143 | Compositional bias | Note=Poly-Thr |
| Hgene | HTT | chr4:3190820 | chr4:39257468 | ENST00000355072 | + | 40 | 67 | 18_38 | 1789 | 3143 | Compositional bias | Note=Poly-Gln |
| Hgene | HTT | chr4:3190820 | chr4:39257468 | ENST00000355072 | + | 40 | 67 | 39_49 | 1789 | 3143 | Compositional bias | Note=Poly-Pro |
| Hgene | HTT | chr4:3190820 | chr4:39257468 | ENST00000355072 | + | 40 | 67 | 63_78 | 1789 | 3143 | Compositional bias | Note=Poly-Pro |
| Hgene | HTT | chr4:3190820 | chr4:39257468 | ENST00000355072 | + | 40 | 67 | 204_241 | 1789 | 3143 | Repeat | Note=HEAT 1 |
| Hgene | HTT | chr4:3190820 | chr4:39257468 | ENST00000355072 | + | 40 | 67 | 246_283 | 1789 | 3143 | Repeat | Note=HEAT 2 |
| Hgene | HTT | chr4:3190820 | chr4:39257468 | ENST00000355072 | + | 40 | 67 | 316_360 | 1789 | 3143 | Repeat | Note=HEAT 3 |
| Hgene | HTT | chr4:3190820 | chr4:39257468 | ENST00000355072 | + | 40 | 67 | 802_839 | 1789 | 3143 | Repeat | Note=HEAT 4 |
| Hgene | HTT | chr4:3190820 | chr4:39257468 | ENST00000355072 | + | 40 | 67 | 902_940 | 1789 | 3143 | Repeat | Note=HEAT 5 |
| Tgene | >WDR19 | chr4:3190820 | chr4:39257468 | ENST00000399820 | + | 25 | 37 | 1020_1053 | 1000 | 1397 | Repeat | Note=TPR 6 |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >HTT | chr4:3190820 | chr4:39257468 | ENST00000355072 | + | 40 | 67 | 2341_2345 | 1789 | 3143 | Compositional bias | Note=Poly-Glu |
| Hgene | >HTT | chr4:3190820 | chr4:39257468 | ENST00000355072 | + | 40 | 67 | 2638_2643 | 1789 | 3143 | Compositional bias | Note=Poly-Glu |
| Hgene | >HTT | chr4:3190820 | chr4:39257468 | ENST00000355072 | + | 40 | 67 | 2395_2404 | 1789 | 3143 | Motif | Nuclear export signal |
| Tgene | WDR19 | chr4:3190820 | chr4:39257468 | ENST00000399820 | + | 25 | 37 | 11_51 | 1000 | 1397 | Repeat | Note=WD 1 |
| Tgene | WDR19 | chr4:3190820 | chr4:39257468 | ENST00000399820 | + | 25 | 37 | 137_175 | 1000 | 1397 | Repeat | Note=WD 4 |
| Tgene | WDR19 | chr4:3190820 | chr4:39257468 | ENST00000399820 | + | 25 | 37 | 273_311 | 1000 | 1397 | Repeat | Note=WD 5 |
| Tgene | WDR19 | chr4:3190820 | chr4:39257468 | ENST00000399820 | + | 25 | 37 | 317_356 | 1000 | 1397 | Repeat | Note=WD 6 |
| Tgene | WDR19 | chr4:3190820 | chr4:39257468 | ENST00000399820 | + | 25 | 37 | 52_92 | 1000 | 1397 | Repeat | Note=WD 2 |
| Tgene | WDR19 | chr4:3190820 | chr4:39257468 | ENST00000399820 | + | 25 | 37 | 736_769 | 1000 | 1397 | Repeat | Note=TPR 1 |
| Tgene | WDR19 | chr4:3190820 | chr4:39257468 | ENST00000399820 | + | 25 | 37 | 775_808 | 1000 | 1397 | Repeat | Note=TPR 2 |
| Tgene | WDR19 | chr4:3190820 | chr4:39257468 | ENST00000399820 | + | 25 | 37 | 840_873 | 1000 | 1397 | Repeat | Note=TPR 3 |
| Tgene | WDR19 | chr4:3190820 | chr4:39257468 | ENST00000399820 | + | 25 | 37 | 895_928 | 1000 | 1397 | Repeat | Note=TPR 4 |
| Tgene | WDR19 | chr4:3190820 | chr4:39257468 | ENST00000399820 | + | 25 | 37 | 951_984 | 1000 | 1397 | Repeat | Note=TPR 5 |
| Tgene | WDR19 | chr4:3190820 | chr4:39257468 | ENST00000399820 | + | 25 | 37 | 95_134 | 1000 | 1397 | Repeat | Note=WD 3 |
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FusionGeneSequence for HTT_WDR19 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_HTT_ENST00000355072_chr4_3190820_+_WDR19_ENST00000399820_chr4_39257468_+_2132aa MATLEKLMKAFESLKSFQQQQQQQQQQQQQQQQQQQQQPPPPPPPPPPPQLPQPPPQAQPLLPQPQPPPPPPPPPPGPAVAEEPLHRPKK ELSATKKDRVNHCLTICENIVAQSVRNSPEFQKLLGIAMELFLLCSDDAESDVRMVADECLNKVIKALMDSNLPRLQLELYKEIKKNGAP RSLRAALWRFAELAHLVRPQKCRPYLVNLLPCLTRTSKRPEESVQETLAAAVPKIMASFGNFANDNEIKVLLKAFIANLKSSSPTIRRTA AGSAVSICQHSRRTQYFYSWLLNVLLGLLVPVEDEHSTLLILGVLLTLRYLVPLLQQQVKDTSLKGSFGVTRKEMEVSPSAEQLVQVYEL TLHHTQHQDHNVVTGALELLQQLFRTPPPELLQTLTAVGGIGQLTAAKEESGGRSRSGSIVELIAGGGSSCSPVLSRKQKGKVLLGEEEA LEDDSESRSDVSSSALTASVKDEISGELAASSGVSTPGSAGHDIITEQPRSQHTLQADSVDLASCDLTSSATDGDEEDILSHSSSQVSAV PSDPAMDLNDGTQASSPISDSSQTTTEGPDSAVTPSDSSEIVLDGTDNQYLGLQIGQPQDEDEEATGILPDEASEAFRNSSMALQQAHLL KNMSHCRQPSDSSVDKFVLRDEATEPGDQENKPCRIKGDIGQSTDDDSAPLVHCVRLLSASFLLTGGKNVLVPDRDVRVSVKALALSCVG AAVALHPESFFSKLYKVPLDTTEYPEEQYVSDILNYIDHGDPQVRGATAILCGTLICSILSRSRFHVGDWMGTIRTLTGNTFSLADCIPL LRKTLKDESSVTCKLACTAVRNCVMSLCSSSYSELGLQLIIDVLTLRNSSYWLVRTELLETLAEIDFRLVSFLEAKAENLHRGAHHYTGL LKLQERVLNNVVIHLLGDEDPRVRHVAAASLIRLVPKLFYKCDQGQADPVVAVARDQSSVYLKLLMHETQPPSHFSVSTITRIYRGYNLL PSITDVTMENNLSRVIAAVSHELITSTTRALTFGCCEALCLLSTAFPVCIWSLGWHCGVPPLSASDESRKSCTVGMATMILTLLSSAWFP LDLSAHQDALILAGNLLAASAPKSLRSSWASEEEANPAATKQEEVWPALGDRALVPMVEQLFSHLLKVINICAHVLDDVAPGPAIKAALP SLTNPPSLSPIRRKGKEKEPGEQASVPLSPKKGSEASAASRQSDTSGPVTTSKSSSLGSFYHLPSYLKLHDVLKATHANYKVTLDLQNST EKFGGFLRSALDVLSQILELATLQDIGKCVEEILGYLKSCFSREPMMATVCVQQLLKTLFGTNLASQFDGLSSNPSKSQGRAQRLGSSSV RPGLYHYCFMAPYTHFTQALADASLRNMVQAEQENDTSGWFDVLQKVSTQLKTNLTSVTKNRADKNAIHNHIRLFEPLVIKALKQYTTTT CVQLQKQVLDLLAQLVQLRVNYCLLDSDQVFIGFVLKQFEYIEVGQFRESEAIIPNIFFFLVLLSYERYHSKQIIGIPKIIQLCDGIMAS GRKAVTHAIPALQPIVHDLFVLRGTNKADAGKELETQKEVVVSMLLRLIQYHQVLEMFILVLQQCHKENEDKWKRLSRQIADIILPMLAK QQMHIDSHEALGVLNTLFEILAPSSLRPVDMLLRSMFVTPNTMASVSTVQLWISGILAILRVLISQSTEDIVLSRIQELSFSPYLISCTV INRLRDGDSTSTLEEHSEGKQIKNLPEETFSRFLLQLVGILLEDIVTKQLKVEMSEQQHTFYCQELGTLLMCLIHIFKSGSEDTTNEDYQ SIALYFEGEKRYLQAGKFFLLCGQYSRALKHFLKCPSSEDNVAIEMAIETVGQAKDELLTNQLIDHLLGENDGMPKDAKYLFRLYMALKQ YREAAQTAIIIAREEQSAGNYRNAHDVLFSMYAELKSQKIKIPSEMATNLMILHSYILVKIHVKNGDHMKGARMLIRVANNISKFPSHIV PILTSTVIECHRAGLKNSAFSFAAMLMRPEYRSKIDAKYKKKIEGMVRRPDISEIEEATTPCPFCKFLLPECELLCPGCKNSIPYCIATG >In-frame_HTT_ENST00000355072_chr4_3190820_+_WDR19_ENST00000288634_chr4_39257468_+_2132aa MATLEKLMKAFESLKSFQQQQQQQQQQQQQQQQQQQQQPPPPPPPPPPPQLPQPPPQAQPLLPQPQPPPPPPPPPPGPAVAEEPLHRPKK ELSATKKDRVNHCLTICENIVAQSVRNSPEFQKLLGIAMELFLLCSDDAESDVRMVADECLNKVIKALMDSNLPRLQLELYKEIKKNGAP RSLRAALWRFAELAHLVRPQKCRPYLVNLLPCLTRTSKRPEESVQETLAAAVPKIMASFGNFANDNEIKVLLKAFIANLKSSSPTIRRTA AGSAVSICQHSRRTQYFYSWLLNVLLGLLVPVEDEHSTLLILGVLLTLRYLVPLLQQQVKDTSLKGSFGVTRKEMEVSPSAEQLVQVYEL TLHHTQHQDHNVVTGALELLQQLFRTPPPELLQTLTAVGGIGQLTAAKEESGGRSRSGSIVELIAGGGSSCSPVLSRKQKGKVLLGEEEA LEDDSESRSDVSSSALTASVKDEISGELAASSGVSTPGSAGHDIITEQPRSQHTLQADSVDLASCDLTSSATDGDEEDILSHSSSQVSAV PSDPAMDLNDGTQASSPISDSSQTTTEGPDSAVTPSDSSEIVLDGTDNQYLGLQIGQPQDEDEEATGILPDEASEAFRNSSMALQQAHLL KNMSHCRQPSDSSVDKFVLRDEATEPGDQENKPCRIKGDIGQSTDDDSAPLVHCVRLLSASFLLTGGKNVLVPDRDVRVSVKALALSCVG AAVALHPESFFSKLYKVPLDTTEYPEEQYVSDILNYIDHGDPQVRGATAILCGTLICSILSRSRFHVGDWMGTIRTLTGNTFSLADCIPL LRKTLKDESSVTCKLACTAVRNCVMSLCSSSYSELGLQLIIDVLTLRNSSYWLVRTELLETLAEIDFRLVSFLEAKAENLHRGAHHYTGL LKLQERVLNNVVIHLLGDEDPRVRHVAAASLIRLVPKLFYKCDQGQADPVVAVARDQSSVYLKLLMHETQPPSHFSVSTITRIYRGYNLL PSITDVTMENNLSRVIAAVSHELITSTTRALTFGCCEALCLLSTAFPVCIWSLGWHCGVPPLSASDESRKSCTVGMATMILTLLSSAWFP LDLSAHQDALILAGNLLAASAPKSLRSSWASEEEANPAATKQEEVWPALGDRALVPMVEQLFSHLLKVINICAHVLDDVAPGPAIKAALP SLTNPPSLSPIRRKGKEKEPGEQASVPLSPKKGSEASAASRQSDTSGPVTTSKSSSLGSFYHLPSYLKLHDVLKATHANYKVTLDLQNST EKFGGFLRSALDVLSQILELATLQDIGKCVEEILGYLKSCFSREPMMATVCVQQLLKTLFGTNLASQFDGLSSNPSKSQGRAQRLGSSSV RPGLYHYCFMAPYTHFTQALADASLRNMVQAEQENDTSGWFDVLQKVSTQLKTNLTSVTKNRADKNAIHNHIRLFEPLVIKALKQYTTTT CVQLQKQVLDLLAQLVQLRVNYCLLDSDQVFIGFVLKQFEYIEVGQFRESEAIIPNIFFFLVLLSYERYHSKQIIGIPKIIQLCDGIMAS GRKAVTHAIPALQPIVHDLFVLRGTNKADAGKELETQKEVVVSMLLRLIQYHQVLEMFILVLQQCHKENEDKWKRLSRQIADIILPMLAK QQMHIDSHEALGVLNTLFEILAPSSLRPVDMLLRSMFVTPNTMASVSTVQLWISGILAILRVLISQSTEDIVLSRIQELSFSPYLISCTV INRLRDGDSTSTLEEHSEGKQIKNLPEETFSRFLLQLVGILLEDIVTKQLKVEMSEQQHTFYCQELGTLLMCLIHIFKSGSEDTTNEDYQ SIALYFEGEKRYLQAGKFFLLCGQYSRALKHFLKCPSSEDNVAIEMAIETVGQAKDELLTNQLIDHLLGENDGMPKDAKYLFRLYMALKQ YREAAQTAIIIAREEQSAGNYRNAHDVLFSMYAELKSQKIKIPSEMATNLMILHSYILVKIHVKNGDHMKGARMLIRVANNISKFPSHIV PILTSTVIECHRAGLKNSAFSFAAMLMRPEYRSKIDAKYKKKIEGMVRRPDISEIEEATTPCPFCKFLLPECELLCPGCKNSIPYCIATG |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_HTT_ENST00000355072_chr4_3190820_+_WDR19_ENST00000399820_chr4_39257468_+_6396nt ATGGCGACCCTGGAAAAGCTGATGAAGGCCTTCGAGTCCCTCAAGTCCTTCCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAG CAGCAGCAGCAGCAGCAGCAACAGCCGCCACCGCCGCCGCCGCCGCCGCCGCCTCCTCAGCTTCCTCAGCCGCCGCCGCAGGCACAGCCG CTGCTGCCTCAGCCGCAGCCGCCCCCGCCGCCGCCCCCGCCGCCACCCGGCCCGGCTGTGGCTGAGGAGCCGCTGCACCGACCAAAGAAA GAACTTTCAGCTACCAAGAAAGACCGTGTGAATCATTGTCTGACAATATGTGAAAACATAGTGGCACAGTCTGTCAGAAATTCTCCAGAA TTTCAGAAACTTCTGGGCATCGCTATGGAACTTTTTCTGCTGTGCAGTGATGACGCAGAGTCAGATGTCAGGATGGTGGCTGACGAATGC CTCAACAAAGTTATCAAAGCTTTGATGGATTCTAATCTTCCAAGGTTACAGCTCGAGCTCTATAAGGAAATTAAAAAGAATGGTGCCCCT CGGAGTTTGCGTGCTGCCCTGTGGAGGTTTGCTGAGCTGGCTCACCTGGTTCGGCCTCAGAAATGCAGGCCTTACCTGGTGAACCTTCTG CCGTGCCTGACTCGAACAAGCAAGAGACCCGAAGAATCAGTCCAGGAGACCTTGGCTGCAGCTGTTCCCAAAATTATGGCTTCTTTTGGC AATTTTGCAAATGACAATGAAATTAAGGTTTTGTTAAAGGCCTTCATAGCGAACCTGAAGTCAAGCTCCCCCACCATTCGGCGGACAGCG GCTGGATCAGCAGTGAGCATCTGCCAGCACTCAAGAAGGACACAATATTTCTATAGTTGGCTACTAAATGTGCTCTTAGGCTTACTCGTT CCTGTCGAGGATGAACACTCCACTCTGCTGATTCTTGGCGTGCTGCTCACCCTGAGGTATTTGGTGCCCTTGCTGCAGCAGCAGGTCAAG GACACAAGCCTGAAAGGCAGCTTCGGAGTGACAAGGAAAGAAATGGAAGTCTCTCCTTCTGCAGAGCAGCTTGTCCAGGTTTATGAACTG ACGTTACATCATACACAGCACCAAGACCACAATGTTGTGACCGGAGCCCTGGAGCTGTTGCAGCAGCTCTTCAGAACGCCTCCACCCGAG CTTCTGCAAACCCTGACCGCAGTCGGGGGCATTGGGCAGCTCACCGCTGCTAAGGAGGAGTCTGGTGGCCGAAGCCGTAGTGGGAGTATT GTGGAACTTATAGCTGGAGGGGGTTCCTCATGCAGCCCTGTCCTTTCAAGAAAACAAAAAGGCAAAGTGCTCTTAGGAGAAGAAGAAGCC TTGGAGGATGACTCTGAATCGAGATCGGATGTCAGCAGCTCTGCCTTAACAGCCTCAGTGAAGGATGAGATCAGTGGAGAGCTGGCTGCT TCTTCAGGGGTTTCCACTCCAGGGTCAGCAGGTCATGACATCATCACAGAACAGCCACGGTCACAGCACACACTGCAGGCGGACTCAGTG GATCTGGCCAGCTGTGACTTGACAAGCTCTGCCACTGATGGGGATGAGGAGGATATCTTGAGCCACAGCTCCAGCCAGGTCAGCGCCGTC CCATCTGACCCTGCCATGGACCTGAATGATGGGACCCAGGCCTCGTCGCCCATCAGCGACAGCTCCCAGACCACCACCGAAGGGCCTGAT TCAGCTGTTACCCCTTCAGACAGTTCTGAAATTGTGTTAGACGGTACCGACAACCAGTATTTGGGCCTGCAGATTGGACAGCCCCAGGAT GAAGATGAGGAAGCCACAGGTATTCTTCCTGATGAAGCCTCGGAGGCCTTCAGGAACTCTTCCATGGCCCTTCAACAGGCACATTTATTG AAAAACATGAGTCACTGCAGGCAGCCTTCTGACAGCAGTGTTGATAAATTTGTGTTGAGAGATGAAGCTACTGAACCGGGTGATCAAGAA AACAAGCCTTGCCGCATCAAAGGTGACATTGGACAGTCCACTGATGATGACTCTGCACCTCTTGTCCATTGTGTCCGCCTTTTATCTGCT TCGTTTTTGCTAACAGGGGGAAAAAATGTGCTGGTTCCGGACAGGGATGTGAGGGTCAGCGTGAAGGCCCTGGCCCTCAGCTGTGTGGGA GCAGCTGTGGCCCTCCACCCGGAATCTTTCTTCAGCAAACTCTATAAAGTTCCTCTTGACACCACGGAATACCCTGAGGAACAGTATGTC TCAGACATCTTGAACTACATCGATCATGGAGACCCACAGGTTCGAGGAGCCACTGCCATTCTCTGTGGGACCCTCATCTGCTCCATCCTC AGCAGGTCCCGCTTCCACGTGGGAGATTGGATGGGCACCATTAGAACCCTCACAGGAAATACATTTTCTTTGGCGGATTGCATTCCTTTG CTGCGGAAAACACTGAAGGATGAGTCTTCTGTTACTTGCAAGTTAGCTTGTACAGCTGTGAGGAACTGTGTCATGAGTCTCTGCAGCAGC AGCTACAGTGAGTTAGGACTGCAGCTGATCATCGATGTGCTGACTCTGAGGAACAGTTCCTATTGGCTGGTGAGGACAGAGCTTCTGGAA ACCCTTGCAGAGATTGACTTCAGGCTGGTGAGCTTTTTGGAGGCAAAAGCAGAAAACTTACACAGAGGGGCTCATCATTATACAGGGCTT TTAAAACTGCAAGAACGAGTGCTCAATAATGTTGTCATCCATTTGCTTGGAGATGAAGACCCCAGGGTGCGACATGTTGCCGCAGCATCA CTAATTAGGCTTGTCCCAAAGCTGTTTTATAAATGTGACCAAGGACAAGCTGATCCAGTAGTGGCCGTGGCAAGAGATCAAAGCAGTGTT TACCTGAAACTTCTCATGCATGAGACGCAGCCTCCATCTCATTTCTCCGTCAGCACAATAACCAGAATATATAGAGGCTATAACCTACTA CCAAGCATAACAGACGTCACTATGGAAAATAACCTTTCAAGAGTTATTGCAGCAGTTTCTCATGAACTAATCACATCAACCACCAGAGCA CTCACATTTGGATGCTGTGAAGCTTTGTGTCTTCTTTCCACTGCCTTCCCAGTTTGCATTTGGAGTTTAGGTTGGCACTGTGGAGTGCCT CCACTGAGTGCCTCAGATGAGTCTAGGAAGAGCTGTACCGTTGGGATGGCCACAATGATTCTGACCCTGCTCTCGTCAGCTTGGTTCCCA TTGGATCTCTCAGCCCATCAAGATGCTTTGATTTTGGCCGGAAACTTGCTTGCAGCCAGTGCTCCCAAATCTCTGAGAAGTTCATGGGCC TCTGAAGAAGAAGCCAACCCAGCAGCCACCAAGCAAGAGGAGGTCTGGCCAGCCCTGGGGGACCGGGCCCTGGTGCCCATGGTGGAGCAG CTCTTCTCTCACCTGCTGAAGGTGATTAACATTTGTGCCCACGTCCTGGATGACGTGGCTCCTGGACCCGCAATAAAGGCAGCCTTGCCT TCTCTAACAAACCCCCCTTCTCTAAGTCCCATCCGACGAAAGGGGAAGGAGAAAGAACCAGGAGAACAAGCATCTGTACCGTTGAGTCCC AAGAAAGGCAGTGAGGCCAGTGCAGCTTCTAGACAATCTGATACCTCAGGTCCTGTTACAACAAGTAAATCCTCATCACTGGGGAGTTTC TATCATCTTCCTTCATACCTCAAACTGCATGATGTCCTGAAAGCTACACACGCTAACTACAAGGTCACGCTGGATCTTCAGAACAGCACG GAAAAGTTTGGAGGGTTTCTCCGCTCAGCCTTGGATGTTCTTTCTCAGATACTAGAGCTGGCCACACTGCAGGACATTGGGAAGTGTGTT GAAGAGATCCTAGGATACCTGAAATCCTGCTTTAGTCGAGAACCAATGATGGCAACTGTTTGTGTTCAACAATTGTTGAAGACTCTCTTT GGCACAAACTTGGCCTCCCAGTTTGATGGCTTATCTTCCAACCCCAGCAAGTCACAAGGCCGAGCACAGCGCCTTGGCTCCTCCAGTGTG AGGCCAGGCTTGTACCACTACTGCTTCATGGCCCCGTACACCCACTTCACCCAGGCCCTCGCTGACGCCAGCCTGAGGAACATGGTGCAG GCGGAGCAGGAGAACGACACCTCGGGATGGTTTGATGTCCTCCAGAAAGTGTCTACCCAGTTGAAGACAAACCTCACGAGTGTCACAAAG AACCGTGCAGATAAGAATGCTATTCATAATCACATTCGTTTGTTTGAACCTCTTGTTATAAAAGCTTTAAAACAGTACACGACTACAACA TGTGTGCAGTTACAGAAGCAGGTTTTAGATTTGCTGGCGCAGCTGGTTCAGTTACGGGTTAATTACTGTCTTCTGGATTCAGATCAGGTG TTTATTGGCTTTGTATTGAAACAGTTTGAATACATTGAAGTGGGCCAGTTCAGGGAATCAGAGGCAATCATTCCAAACATCTTTTTCTTC TTGGTATTACTATCTTATGAACGCTATCATTCAAAACAGATCATTGGAATTCCTAAAATCATTCAGCTCTGTGATGGCATCATGGCCAGT GGAAGGAAGGCTGTGACACATGCCATACCGGCTCTGCAGCCCATAGTCCACGACCTCTTTGTATTAAGAGGAACAAATAAAGCTGATGCA GGAAAAGAGCTTGAAACCCAAAAAGAGGTGGTGGTGTCAATGTTACTGAGACTCATCCAGTACCATCAGGTGTTGGAGATGTTCATTCTT GTCCTGCAGCAGTGCCACAAGGAGAATGAAGACAAGTGGAAGCGACTGTCTCGACAGATAGCTGACATCATCCTCCCAATGTTAGCCAAA CAGCAGATGCACATTGACTCTCATGAAGCCCTTGGAGTGTTAAATACATTATTTGAGATTTTGGCCCCTTCCTCCCTCCGTCCGGTAGAC ATGCTTTTACGGAGTATGTTCGTCACTCCAAACACAATGGCGTCCGTGAGCACTGTTCAACTGTGGATATCGGGAATTCTGGCCATTTTG AGGGTTCTGATTTCCCAGTCAACTGAAGATATTGTTCTTTCTCGTATTCAGGAGCTCTCCTTCTCTCCGTATTTAATCTCCTGTACAGTA ATTAATAGGTTAAGAGATGGGGACAGTACTTCAACGCTAGAAGAACACAGTGAAGGGAAACAAATAAAGAATTTGCCAGAAGAAACATTT TCAAGGTTTCTATTACAACTGGTTGGTATTCTTTTAGAAGACATTGTTACAAAACAGCTGAAGGTGGAAATGAGTGAGCAGCAACATACT TTCTATTGCCAGGAACTAGGCACACTGCTAATGTGTCTGATCCACATCTTCAAGTCTGGTTCTGAAGACACTACTAATGAAGACTATCAA AGCATTGCCTTATACTTTGAAGGAGAAAAGAGATATCTTCAGGCTGGAAAATTCTTCTTGCTGTGTGGCCAATATTCACGAGCACTTAAA CACTTCCTGAAATGCCCAAGCTCGGAAGATAATGTGGCAATAGAAATGGCAATTGAAACTGTTGGTCAGGCCAAAGATGAACTGCTGACC AATCAGCTGATAGACCATCTCCTGGGGGAGAACGATGGCATGCCTAAGGATGCCAAGTACCTGTTCCGCTTGTACATGGCTCTGAAGCAA TACCGAGAAGCTGCCCAGACTGCCATCATCATTGCCAGAGAAGAGCAGTCTGCAGGCAACTACCGGAATGCACACGATGTTCTCTTCAGT ATGTATGCAGAACTGAAATCCCAGAAGATCAAAATTCCCTCCGAGATGGCCACCAACCTCATGATTCTGCACAGCTATATACTAGTAAAG ATTCATGTTAAAAATGGAGATCACATGAAAGGGGCTCGCATGCTCATTCGGGTGGCCAACAACATCAGCAAATTTCCATCACACATTGTA CCCATCCTGACGTCAACTGTGATTGAGTGTCACAGGGCAGGCCTGAAGAACTCTGCTTTCAGCTTCGCAGCTATGTTGATGAGGCCTGAA TACCGCAGCAAAATAGATGCCAAATACAAAAAGAAGATCGAGGGAATGGTCAGGAGACCCGATATATCTGAGATAGAAGAGGCCACGACT CCATGTCCATTCTGCAAATTTCTTCTCCCAGAGTGTGAACTCCTCTGTCCTGGATGTAAAAACAGTATCCCATATTGCATTGCAACAGGT CGACACATGTTGAAAGATGACTGGACGGTGTGTCCACATTGTGACTTCCCTGCTCTATACTCAGAATTGAAGATCATGCTAAACACTGAA AGCACATGTCCTATGTGTTCAGAAAGATTAAACGCTGCTCAGCTGAAAAAGATTTCAGACTGTACCCAGTACCTGCGAACGGAGGAGGAA >In-frame_HTT_ENST00000355072_chr4_3190820_+_WDR19_ENST00000288634_chr4_39257468_+_6396nt ATGGCGACCCTGGAAAAGCTGATGAAGGCCTTCGAGTCCCTCAAGTCCTTCCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAG CAGCAGCAGCAGCAGCAGCAACAGCCGCCACCGCCGCCGCCGCCGCCGCCGCCTCCTCAGCTTCCTCAGCCGCCGCCGCAGGCACAGCCG CTGCTGCCTCAGCCGCAGCCGCCCCCGCCGCCGCCCCCGCCGCCACCCGGCCCGGCTGTGGCTGAGGAGCCGCTGCACCGACCAAAGAAA GAACTTTCAGCTACCAAGAAAGACCGTGTGAATCATTGTCTGACAATATGTGAAAACATAGTGGCACAGTCTGTCAGAAATTCTCCAGAA TTTCAGAAACTTCTGGGCATCGCTATGGAACTTTTTCTGCTGTGCAGTGATGACGCAGAGTCAGATGTCAGGATGGTGGCTGACGAATGC CTCAACAAAGTTATCAAAGCTTTGATGGATTCTAATCTTCCAAGGTTACAGCTCGAGCTCTATAAGGAAATTAAAAAGAATGGTGCCCCT CGGAGTTTGCGTGCTGCCCTGTGGAGGTTTGCTGAGCTGGCTCACCTGGTTCGGCCTCAGAAATGCAGGCCTTACCTGGTGAACCTTCTG CCGTGCCTGACTCGAACAAGCAAGAGACCCGAAGAATCAGTCCAGGAGACCTTGGCTGCAGCTGTTCCCAAAATTATGGCTTCTTTTGGC AATTTTGCAAATGACAATGAAATTAAGGTTTTGTTAAAGGCCTTCATAGCGAACCTGAAGTCAAGCTCCCCCACCATTCGGCGGACAGCG GCTGGATCAGCAGTGAGCATCTGCCAGCACTCAAGAAGGACACAATATTTCTATAGTTGGCTACTAAATGTGCTCTTAGGCTTACTCGTT CCTGTCGAGGATGAACACTCCACTCTGCTGATTCTTGGCGTGCTGCTCACCCTGAGGTATTTGGTGCCCTTGCTGCAGCAGCAGGTCAAG GACACAAGCCTGAAAGGCAGCTTCGGAGTGACAAGGAAAGAAATGGAAGTCTCTCCTTCTGCAGAGCAGCTTGTCCAGGTTTATGAACTG ACGTTACATCATACACAGCACCAAGACCACAATGTTGTGACCGGAGCCCTGGAGCTGTTGCAGCAGCTCTTCAGAACGCCTCCACCCGAG CTTCTGCAAACCCTGACCGCAGTCGGGGGCATTGGGCAGCTCACCGCTGCTAAGGAGGAGTCTGGTGGCCGAAGCCGTAGTGGGAGTATT GTGGAACTTATAGCTGGAGGGGGTTCCTCATGCAGCCCTGTCCTTTCAAGAAAACAAAAAGGCAAAGTGCTCTTAGGAGAAGAAGAAGCC TTGGAGGATGACTCTGAATCGAGATCGGATGTCAGCAGCTCTGCCTTAACAGCCTCAGTGAAGGATGAGATCAGTGGAGAGCTGGCTGCT TCTTCAGGGGTTTCCACTCCAGGGTCAGCAGGTCATGACATCATCACAGAACAGCCACGGTCACAGCACACACTGCAGGCGGACTCAGTG GATCTGGCCAGCTGTGACTTGACAAGCTCTGCCACTGATGGGGATGAGGAGGATATCTTGAGCCACAGCTCCAGCCAGGTCAGCGCCGTC CCATCTGACCCTGCCATGGACCTGAATGATGGGACCCAGGCCTCGTCGCCCATCAGCGACAGCTCCCAGACCACCACCGAAGGGCCTGAT TCAGCTGTTACCCCTTCAGACAGTTCTGAAATTGTGTTAGACGGTACCGACAACCAGTATTTGGGCCTGCAGATTGGACAGCCCCAGGAT GAAGATGAGGAAGCCACAGGTATTCTTCCTGATGAAGCCTCGGAGGCCTTCAGGAACTCTTCCATGGCCCTTCAACAGGCACATTTATTG AAAAACATGAGTCACTGCAGGCAGCCTTCTGACAGCAGTGTTGATAAATTTGTGTTGAGAGATGAAGCTACTGAACCGGGTGATCAAGAA AACAAGCCTTGCCGCATCAAAGGTGACATTGGACAGTCCACTGATGATGACTCTGCACCTCTTGTCCATTGTGTCCGCCTTTTATCTGCT TCGTTTTTGCTAACAGGGGGAAAAAATGTGCTGGTTCCGGACAGGGATGTGAGGGTCAGCGTGAAGGCCCTGGCCCTCAGCTGTGTGGGA GCAGCTGTGGCCCTCCACCCGGAATCTTTCTTCAGCAAACTCTATAAAGTTCCTCTTGACACCACGGAATACCCTGAGGAACAGTATGTC TCAGACATCTTGAACTACATCGATCATGGAGACCCACAGGTTCGAGGAGCCACTGCCATTCTCTGTGGGACCCTCATCTGCTCCATCCTC AGCAGGTCCCGCTTCCACGTGGGAGATTGGATGGGCACCATTAGAACCCTCACAGGAAATACATTTTCTTTGGCGGATTGCATTCCTTTG CTGCGGAAAACACTGAAGGATGAGTCTTCTGTTACTTGCAAGTTAGCTTGTACAGCTGTGAGGAACTGTGTCATGAGTCTCTGCAGCAGC AGCTACAGTGAGTTAGGACTGCAGCTGATCATCGATGTGCTGACTCTGAGGAACAGTTCCTATTGGCTGGTGAGGACAGAGCTTCTGGAA ACCCTTGCAGAGATTGACTTCAGGCTGGTGAGCTTTTTGGAGGCAAAAGCAGAAAACTTACACAGAGGGGCTCATCATTATACAGGGCTT TTAAAACTGCAAGAACGAGTGCTCAATAATGTTGTCATCCATTTGCTTGGAGATGAAGACCCCAGGGTGCGACATGTTGCCGCAGCATCA CTAATTAGGCTTGTCCCAAAGCTGTTTTATAAATGTGACCAAGGACAAGCTGATCCAGTAGTGGCCGTGGCAAGAGATCAAAGCAGTGTT TACCTGAAACTTCTCATGCATGAGACGCAGCCTCCATCTCATTTCTCCGTCAGCACAATAACCAGAATATATAGAGGCTATAACCTACTA CCAAGCATAACAGACGTCACTATGGAAAATAACCTTTCAAGAGTTATTGCAGCAGTTTCTCATGAACTAATCACATCAACCACCAGAGCA CTCACATTTGGATGCTGTGAAGCTTTGTGTCTTCTTTCCACTGCCTTCCCAGTTTGCATTTGGAGTTTAGGTTGGCACTGTGGAGTGCCT CCACTGAGTGCCTCAGATGAGTCTAGGAAGAGCTGTACCGTTGGGATGGCCACAATGATTCTGACCCTGCTCTCGTCAGCTTGGTTCCCA TTGGATCTCTCAGCCCATCAAGATGCTTTGATTTTGGCCGGAAACTTGCTTGCAGCCAGTGCTCCCAAATCTCTGAGAAGTTCATGGGCC TCTGAAGAAGAAGCCAACCCAGCAGCCACCAAGCAAGAGGAGGTCTGGCCAGCCCTGGGGGACCGGGCCCTGGTGCCCATGGTGGAGCAG CTCTTCTCTCACCTGCTGAAGGTGATTAACATTTGTGCCCACGTCCTGGATGACGTGGCTCCTGGACCCGCAATAAAGGCAGCCTTGCCT TCTCTAACAAACCCCCCTTCTCTAAGTCCCATCCGACGAAAGGGGAAGGAGAAAGAACCAGGAGAACAAGCATCTGTACCGTTGAGTCCC AAGAAAGGCAGTGAGGCCAGTGCAGCTTCTAGACAATCTGATACCTCAGGTCCTGTTACAACAAGTAAATCCTCATCACTGGGGAGTTTC TATCATCTTCCTTCATACCTCAAACTGCATGATGTCCTGAAAGCTACACACGCTAACTACAAGGTCACGCTGGATCTTCAGAACAGCACG GAAAAGTTTGGAGGGTTTCTCCGCTCAGCCTTGGATGTTCTTTCTCAGATACTAGAGCTGGCCACACTGCAGGACATTGGGAAGTGTGTT GAAGAGATCCTAGGATACCTGAAATCCTGCTTTAGTCGAGAACCAATGATGGCAACTGTTTGTGTTCAACAATTGTTGAAGACTCTCTTT GGCACAAACTTGGCCTCCCAGTTTGATGGCTTATCTTCCAACCCCAGCAAGTCACAAGGCCGAGCACAGCGCCTTGGCTCCTCCAGTGTG AGGCCAGGCTTGTACCACTACTGCTTCATGGCCCCGTACACCCACTTCACCCAGGCCCTCGCTGACGCCAGCCTGAGGAACATGGTGCAG GCGGAGCAGGAGAACGACACCTCGGGATGGTTTGATGTCCTCCAGAAAGTGTCTACCCAGTTGAAGACAAACCTCACGAGTGTCACAAAG AACCGTGCAGATAAGAATGCTATTCATAATCACATTCGTTTGTTTGAACCTCTTGTTATAAAAGCTTTAAAACAGTACACGACTACAACA TGTGTGCAGTTACAGAAGCAGGTTTTAGATTTGCTGGCGCAGCTGGTTCAGTTACGGGTTAATTACTGTCTTCTGGATTCAGATCAGGTG TTTATTGGCTTTGTATTGAAACAGTTTGAATACATTGAAGTGGGCCAGTTCAGGGAATCAGAGGCAATCATTCCAAACATCTTTTTCTTC TTGGTATTACTATCTTATGAACGCTATCATTCAAAACAGATCATTGGAATTCCTAAAATCATTCAGCTCTGTGATGGCATCATGGCCAGT GGAAGGAAGGCTGTGACACATGCCATACCGGCTCTGCAGCCCATAGTCCACGACCTCTTTGTATTAAGAGGAACAAATAAAGCTGATGCA GGAAAAGAGCTTGAAACCCAAAAAGAGGTGGTGGTGTCAATGTTACTGAGACTCATCCAGTACCATCAGGTGTTGGAGATGTTCATTCTT GTCCTGCAGCAGTGCCACAAGGAGAATGAAGACAAGTGGAAGCGACTGTCTCGACAGATAGCTGACATCATCCTCCCAATGTTAGCCAAA CAGCAGATGCACATTGACTCTCATGAAGCCCTTGGAGTGTTAAATACATTATTTGAGATTTTGGCCCCTTCCTCCCTCCGTCCGGTAGAC ATGCTTTTACGGAGTATGTTCGTCACTCCAAACACAATGGCGTCCGTGAGCACTGTTCAACTGTGGATATCGGGAATTCTGGCCATTTTG AGGGTTCTGATTTCCCAGTCAACTGAAGATATTGTTCTTTCTCGTATTCAGGAGCTCTCCTTCTCTCCGTATTTAATCTCCTGTACAGTA ATTAATAGGTTAAGAGATGGGGACAGTACTTCAACGCTAGAAGAACACAGTGAAGGGAAACAAATAAAGAATTTGCCAGAAGAAACATTT TCAAGGTTTCTATTACAACTGGTTGGTATTCTTTTAGAAGACATTGTTACAAAACAGCTGAAGGTGGAAATGAGTGAGCAGCAACATACT TTCTATTGCCAGGAACTAGGCACACTGCTAATGTGTCTGATCCACATCTTCAAGTCTGGTTCTGAAGACACTACTAATGAAGACTATCAA AGCATTGCCTTATACTTTGAAGGAGAAAAGAGATATCTTCAGGCTGGAAAATTCTTCTTGCTGTGTGGCCAATATTCACGAGCACTTAAA CACTTCCTGAAATGCCCAAGCTCGGAAGATAATGTGGCAATAGAAATGGCAATTGAAACTGTTGGTCAGGCCAAAGATGAACTGCTGACC AATCAGCTGATAGACCATCTCCTGGGGGAGAACGATGGCATGCCTAAGGATGCCAAGTACCTGTTCCGCTTGTACATGGCTCTGAAGCAA TACCGAGAAGCTGCCCAGACTGCCATCATCATTGCCAGAGAAGAGCAGTCTGCAGGCAACTACCGGAATGCACACGATGTTCTCTTCAGT ATGTATGCAGAACTGAAATCCCAGAAGATCAAAATTCCCTCCGAGATGGCCACCAACCTCATGATTCTGCACAGCTATATACTAGTAAAG ATTCATGTTAAAAATGGAGATCACATGAAAGGGGCTCGCATGCTCATTCGGGTGGCCAACAACATCAGCAAATTTCCATCACACATTGTA CCCATCCTGACGTCAACTGTGATTGAGTGTCACAGGGCAGGCCTGAAGAACTCTGCTTTCAGCTTCGCAGCTATGTTGATGAGGCCTGAA TACCGCAGCAAAATAGATGCCAAATACAAAAAGAAGATCGAGGGAATGGTCAGGAGACCCGATATATCTGAGATAGAAGAGGCCACGACT CCATGTCCATTCTGCAAATTTCTTCTCCCAGAGTGTGAACTCCTCTGTCCTGGATGTAAAAACAGTATCCCATATTGCATTGCAACAGGT CGACACATGTTGAAAGATGACTGGACGGTGTGTCCACATTGTGACTTCCCTGCTCTATACTCAGAATTGAAGATCATGCTAAACACTGAA AGCACATGTCCTATGTGTTCAGAAAGATTAAACGCTGCTCAGCTGAAAAAGATTTCAGACTGTACCCAGTACCTGCGAACGGAGGAGGAA |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_HTT_ENST00000355072_chr4_3190820_+_WDR19_ENST00000399820_chr4_39257468_+_6878nt GCTGCCGGGACGGGTCCAAGATGGACGGCCGCTCAGGTTCTGCTTTTACCTGCGGCCCAGAGCCCCATTCATTGCCCCGGTGCTGAGCGG CGCCGCGAGTCGGCCCGAGGCCTCCGGGGACTGCCGTGCCGGGCGGGAGACCGCCATGGCGACCCTGGAAAAGCTGATGAAGGCCTTCGA GTCCCTCAAGTCCTTCCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAACAGCCGCCACCGCC GCCGCCGCCGCCGCCGCCTCCTCAGCTTCCTCAGCCGCCGCCGCAGGCACAGCCGCTGCTGCCTCAGCCGCAGCCGCCCCCGCCGCCGCC CCCGCCGCCACCCGGCCCGGCTGTGGCTGAGGAGCCGCTGCACCGACCAAAGAAAGAACTTTCAGCTACCAAGAAAGACCGTGTGAATCA TTGTCTGACAATATGTGAAAACATAGTGGCACAGTCTGTCAGAAATTCTCCAGAATTTCAGAAACTTCTGGGCATCGCTATGGAACTTTT TCTGCTGTGCAGTGATGACGCAGAGTCAGATGTCAGGATGGTGGCTGACGAATGCCTCAACAAAGTTATCAAAGCTTTGATGGATTCTAA TCTTCCAAGGTTACAGCTCGAGCTCTATAAGGAAATTAAAAAGAATGGTGCCCCTCGGAGTTTGCGTGCTGCCCTGTGGAGGTTTGCTGA GCTGGCTCACCTGGTTCGGCCTCAGAAATGCAGGCCTTACCTGGTGAACCTTCTGCCGTGCCTGACTCGAACAAGCAAGAGACCCGAAGA ATCAGTCCAGGAGACCTTGGCTGCAGCTGTTCCCAAAATTATGGCTTCTTTTGGCAATTTTGCAAATGACAATGAAATTAAGGTTTTGTT AAAGGCCTTCATAGCGAACCTGAAGTCAAGCTCCCCCACCATTCGGCGGACAGCGGCTGGATCAGCAGTGAGCATCTGCCAGCACTCAAG AAGGACACAATATTTCTATAGTTGGCTACTAAATGTGCTCTTAGGCTTACTCGTTCCTGTCGAGGATGAACACTCCACTCTGCTGATTCT TGGCGTGCTGCTCACCCTGAGGTATTTGGTGCCCTTGCTGCAGCAGCAGGTCAAGGACACAAGCCTGAAAGGCAGCTTCGGAGTGACAAG GAAAGAAATGGAAGTCTCTCCTTCTGCAGAGCAGCTTGTCCAGGTTTATGAACTGACGTTACATCATACACAGCACCAAGACCACAATGT TGTGACCGGAGCCCTGGAGCTGTTGCAGCAGCTCTTCAGAACGCCTCCACCCGAGCTTCTGCAAACCCTGACCGCAGTCGGGGGCATTGG GCAGCTCACCGCTGCTAAGGAGGAGTCTGGTGGCCGAAGCCGTAGTGGGAGTATTGTGGAACTTATAGCTGGAGGGGGTTCCTCATGCAG CCCTGTCCTTTCAAGAAAACAAAAAGGCAAAGTGCTCTTAGGAGAAGAAGAAGCCTTGGAGGATGACTCTGAATCGAGATCGGATGTCAG CAGCTCTGCCTTAACAGCCTCAGTGAAGGATGAGATCAGTGGAGAGCTGGCTGCTTCTTCAGGGGTTTCCACTCCAGGGTCAGCAGGTCA TGACATCATCACAGAACAGCCACGGTCACAGCACACACTGCAGGCGGACTCAGTGGATCTGGCCAGCTGTGACTTGACAAGCTCTGCCAC TGATGGGGATGAGGAGGATATCTTGAGCCACAGCTCCAGCCAGGTCAGCGCCGTCCCATCTGACCCTGCCATGGACCTGAATGATGGGAC CCAGGCCTCGTCGCCCATCAGCGACAGCTCCCAGACCACCACCGAAGGGCCTGATTCAGCTGTTACCCCTTCAGACAGTTCTGAAATTGT GTTAGACGGTACCGACAACCAGTATTTGGGCCTGCAGATTGGACAGCCCCAGGATGAAGATGAGGAAGCCACAGGTATTCTTCCTGATGA AGCCTCGGAGGCCTTCAGGAACTCTTCCATGGCCCTTCAACAGGCACATTTATTGAAAAACATGAGTCACTGCAGGCAGCCTTCTGACAG CAGTGTTGATAAATTTGTGTTGAGAGATGAAGCTACTGAACCGGGTGATCAAGAAAACAAGCCTTGCCGCATCAAAGGTGACATTGGACA GTCCACTGATGATGACTCTGCACCTCTTGTCCATTGTGTCCGCCTTTTATCTGCTTCGTTTTTGCTAACAGGGGGAAAAAATGTGCTGGT TCCGGACAGGGATGTGAGGGTCAGCGTGAAGGCCCTGGCCCTCAGCTGTGTGGGAGCAGCTGTGGCCCTCCACCCGGAATCTTTCTTCAG CAAACTCTATAAAGTTCCTCTTGACACCACGGAATACCCTGAGGAACAGTATGTCTCAGACATCTTGAACTACATCGATCATGGAGACCC ACAGGTTCGAGGAGCCACTGCCATTCTCTGTGGGACCCTCATCTGCTCCATCCTCAGCAGGTCCCGCTTCCACGTGGGAGATTGGATGGG CACCATTAGAACCCTCACAGGAAATACATTTTCTTTGGCGGATTGCATTCCTTTGCTGCGGAAAACACTGAAGGATGAGTCTTCTGTTAC TTGCAAGTTAGCTTGTACAGCTGTGAGGAACTGTGTCATGAGTCTCTGCAGCAGCAGCTACAGTGAGTTAGGACTGCAGCTGATCATCGA TGTGCTGACTCTGAGGAACAGTTCCTATTGGCTGGTGAGGACAGAGCTTCTGGAAACCCTTGCAGAGATTGACTTCAGGCTGGTGAGCTT TTTGGAGGCAAAAGCAGAAAACTTACACAGAGGGGCTCATCATTATACAGGGCTTTTAAAACTGCAAGAACGAGTGCTCAATAATGTTGT CATCCATTTGCTTGGAGATGAAGACCCCAGGGTGCGACATGTTGCCGCAGCATCACTAATTAGGCTTGTCCCAAAGCTGTTTTATAAATG TGACCAAGGACAAGCTGATCCAGTAGTGGCCGTGGCAAGAGATCAAAGCAGTGTTTACCTGAAACTTCTCATGCATGAGACGCAGCCTCC ATCTCATTTCTCCGTCAGCACAATAACCAGAATATATAGAGGCTATAACCTACTACCAAGCATAACAGACGTCACTATGGAAAATAACCT TTCAAGAGTTATTGCAGCAGTTTCTCATGAACTAATCACATCAACCACCAGAGCACTCACATTTGGATGCTGTGAAGCTTTGTGTCTTCT TTCCACTGCCTTCCCAGTTTGCATTTGGAGTTTAGGTTGGCACTGTGGAGTGCCTCCACTGAGTGCCTCAGATGAGTCTAGGAAGAGCTG TACCGTTGGGATGGCCACAATGATTCTGACCCTGCTCTCGTCAGCTTGGTTCCCATTGGATCTCTCAGCCCATCAAGATGCTTTGATTTT GGCCGGAAACTTGCTTGCAGCCAGTGCTCCCAAATCTCTGAGAAGTTCATGGGCCTCTGAAGAAGAAGCCAACCCAGCAGCCACCAAGCA AGAGGAGGTCTGGCCAGCCCTGGGGGACCGGGCCCTGGTGCCCATGGTGGAGCAGCTCTTCTCTCACCTGCTGAAGGTGATTAACATTTG TGCCCACGTCCTGGATGACGTGGCTCCTGGACCCGCAATAAAGGCAGCCTTGCCTTCTCTAACAAACCCCCCTTCTCTAAGTCCCATCCG ACGAAAGGGGAAGGAGAAAGAACCAGGAGAACAAGCATCTGTACCGTTGAGTCCCAAGAAAGGCAGTGAGGCCAGTGCAGCTTCTAGACA ATCTGATACCTCAGGTCCTGTTACAACAAGTAAATCCTCATCACTGGGGAGTTTCTATCATCTTCCTTCATACCTCAAACTGCATGATGT CCTGAAAGCTACACACGCTAACTACAAGGTCACGCTGGATCTTCAGAACAGCACGGAAAAGTTTGGAGGGTTTCTCCGCTCAGCCTTGGA TGTTCTTTCTCAGATACTAGAGCTGGCCACACTGCAGGACATTGGGAAGTGTGTTGAAGAGATCCTAGGATACCTGAAATCCTGCTTTAG TCGAGAACCAATGATGGCAACTGTTTGTGTTCAACAATTGTTGAAGACTCTCTTTGGCACAAACTTGGCCTCCCAGTTTGATGGCTTATC TTCCAACCCCAGCAAGTCACAAGGCCGAGCACAGCGCCTTGGCTCCTCCAGTGTGAGGCCAGGCTTGTACCACTACTGCTTCATGGCCCC GTACACCCACTTCACCCAGGCCCTCGCTGACGCCAGCCTGAGGAACATGGTGCAGGCGGAGCAGGAGAACGACACCTCGGGATGGTTTGA TGTCCTCCAGAAAGTGTCTACCCAGTTGAAGACAAACCTCACGAGTGTCACAAAGAACCGTGCAGATAAGAATGCTATTCATAATCACAT TCGTTTGTTTGAACCTCTTGTTATAAAAGCTTTAAAACAGTACACGACTACAACATGTGTGCAGTTACAGAAGCAGGTTTTAGATTTGCT GGCGCAGCTGGTTCAGTTACGGGTTAATTACTGTCTTCTGGATTCAGATCAGGTGTTTATTGGCTTTGTATTGAAACAGTTTGAATACAT TGAAGTGGGCCAGTTCAGGGAATCAGAGGCAATCATTCCAAACATCTTTTTCTTCTTGGTATTACTATCTTATGAACGCTATCATTCAAA ACAGATCATTGGAATTCCTAAAATCATTCAGCTCTGTGATGGCATCATGGCCAGTGGAAGGAAGGCTGTGACACATGCCATACCGGCTCT GCAGCCCATAGTCCACGACCTCTTTGTATTAAGAGGAACAAATAAAGCTGATGCAGGAAAAGAGCTTGAAACCCAAAAAGAGGTGGTGGT GTCAATGTTACTGAGACTCATCCAGTACCATCAGGTGTTGGAGATGTTCATTCTTGTCCTGCAGCAGTGCCACAAGGAGAATGAAGACAA GTGGAAGCGACTGTCTCGACAGATAGCTGACATCATCCTCCCAATGTTAGCCAAACAGCAGATGCACATTGACTCTCATGAAGCCCTTGG AGTGTTAAATACATTATTTGAGATTTTGGCCCCTTCCTCCCTCCGTCCGGTAGACATGCTTTTACGGAGTATGTTCGTCACTCCAAACAC AATGGCGTCCGTGAGCACTGTTCAACTGTGGATATCGGGAATTCTGGCCATTTTGAGGGTTCTGATTTCCCAGTCAACTGAAGATATTGT TCTTTCTCGTATTCAGGAGCTCTCCTTCTCTCCGTATTTAATCTCCTGTACAGTAATTAATAGGTTAAGAGATGGGGACAGTACTTCAAC GCTAGAAGAACACAGTGAAGGGAAACAAATAAAGAATTTGCCAGAAGAAACATTTTCAAGGTTTCTATTACAACTGGTTGGTATTCTTTT AGAAGACATTGTTACAAAACAGCTGAAGGTGGAAATGAGTGAGCAGCAACATACTTTCTATTGCCAGGAACTAGGCACACTGCTAATGTG TCTGATCCACATCTTCAAGTCTGGTTCTGAAGACACTACTAATGAAGACTATCAAAGCATTGCCTTATACTTTGAAGGAGAAAAGAGATA TCTTCAGGCTGGAAAATTCTTCTTGCTGTGTGGCCAATATTCACGAGCACTTAAACACTTCCTGAAATGCCCAAGCTCGGAAGATAATGT GGCAATAGAAATGGCAATTGAAACTGTTGGTCAGGCCAAAGATGAACTGCTGACCAATCAGCTGATAGACCATCTCCTGGGGGAGAACGA TGGCATGCCTAAGGATGCCAAGTACCTGTTCCGCTTGTACATGGCTCTGAAGCAATACCGAGAAGCTGCCCAGACTGCCATCATCATTGC CAGAGAAGAGCAGTCTGCAGGCAACTACCGGAATGCACACGATGTTCTCTTCAGTATGTATGCAGAACTGAAATCCCAGAAGATCAAAAT TCCCTCCGAGATGGCCACCAACCTCATGATTCTGCACAGCTATATACTAGTAAAGATTCATGTTAAAAATGGAGATCACATGAAAGGGGC TCGCATGCTCATTCGGGTGGCCAACAACATCAGCAAATTTCCATCACACATTGTACCCATCCTGACGTCAACTGTGATTGAGTGTCACAG GGCAGGCCTGAAGAACTCTGCTTTCAGCTTCGCAGCTATGTTGATGAGGCCTGAATACCGCAGCAAAATAGATGCCAAATACAAAAAGAA GATCGAGGGAATGGTCAGGAGACCCGATATATCTGAGATAGAAGAGGCCACGACTCCATGTCCATTCTGCAAATTTCTTCTCCCAGAGTG TGAACTCCTCTGTCCTGGATGTAAAAACAGTATCCCATATTGCATTGCAACAGGTCGACACATGTTGAAAGATGACTGGACGGTGTGTCC ACATTGTGACTTCCCTGCTCTATACTCAGAATTGAAGATCATGCTAAACACTGAAAGCACATGTCCTATGTGTTCAGAAAGATTAAACGC TGCTCAGCTGAAAAAGATTTCAGACTGTACCCAGTACCTGCGAACGGAGGAGGAACTGTGATTGGCACGTGCAGATACAATGCTCCTGAG AAGACAGCATTTTCCACAGGAGGCTGTTTCCTCCCCTGGTGGATTTAAGAGACGGTCCTTTCTGGATACAGAGAAATGAAACAACGGTGA CCTCTCCAGGTCGGCACTTTCCACTTCTGTACGGTGGCAAAACGATGACATGTAACCTTGCTGTTTATTGTACTTTGTATATTATTTCCT CTTCAAAGTCTTTCTTACACACTCTATCCTCTGCACTGTTAATAGTAACCTATGACATAATTGTAAATATTCAGCTTTTTGCTAACTTTT >In-frame_HTT_ENST00000355072_chr4_3190820_+_WDR19_ENST00000288634_chr4_39257468_+_6848nt GCTGCCGGGACGGGTCCAAGATGGACGGCCGCTCAGGTTCTGCTTTTACCTGCGGCCCAGAGCCCCATTCATTGCCCCGGTGCTGAGCGG CGCCGCGAGTCGGCCCGAGGCCTCCGGGGACTGCCGTGCCGGGCGGGAGACCGCCATGGCGACCCTGGAAAAGCTGATGAAGGCCTTCGA GTCCCTCAAGTCCTTCCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAACAGCCGCCACCGCC GCCGCCGCCGCCGCCGCCTCCTCAGCTTCCTCAGCCGCCGCCGCAGGCACAGCCGCTGCTGCCTCAGCCGCAGCCGCCCCCGCCGCCGCC CCCGCCGCCACCCGGCCCGGCTGTGGCTGAGGAGCCGCTGCACCGACCAAAGAAAGAACTTTCAGCTACCAAGAAAGACCGTGTGAATCA TTGTCTGACAATATGTGAAAACATAGTGGCACAGTCTGTCAGAAATTCTCCAGAATTTCAGAAACTTCTGGGCATCGCTATGGAACTTTT TCTGCTGTGCAGTGATGACGCAGAGTCAGATGTCAGGATGGTGGCTGACGAATGCCTCAACAAAGTTATCAAAGCTTTGATGGATTCTAA TCTTCCAAGGTTACAGCTCGAGCTCTATAAGGAAATTAAAAAGAATGGTGCCCCTCGGAGTTTGCGTGCTGCCCTGTGGAGGTTTGCTGA GCTGGCTCACCTGGTTCGGCCTCAGAAATGCAGGCCTTACCTGGTGAACCTTCTGCCGTGCCTGACTCGAACAAGCAAGAGACCCGAAGA ATCAGTCCAGGAGACCTTGGCTGCAGCTGTTCCCAAAATTATGGCTTCTTTTGGCAATTTTGCAAATGACAATGAAATTAAGGTTTTGTT AAAGGCCTTCATAGCGAACCTGAAGTCAAGCTCCCCCACCATTCGGCGGACAGCGGCTGGATCAGCAGTGAGCATCTGCCAGCACTCAAG AAGGACACAATATTTCTATAGTTGGCTACTAAATGTGCTCTTAGGCTTACTCGTTCCTGTCGAGGATGAACACTCCACTCTGCTGATTCT TGGCGTGCTGCTCACCCTGAGGTATTTGGTGCCCTTGCTGCAGCAGCAGGTCAAGGACACAAGCCTGAAAGGCAGCTTCGGAGTGACAAG GAAAGAAATGGAAGTCTCTCCTTCTGCAGAGCAGCTTGTCCAGGTTTATGAACTGACGTTACATCATACACAGCACCAAGACCACAATGT TGTGACCGGAGCCCTGGAGCTGTTGCAGCAGCTCTTCAGAACGCCTCCACCCGAGCTTCTGCAAACCCTGACCGCAGTCGGGGGCATTGG GCAGCTCACCGCTGCTAAGGAGGAGTCTGGTGGCCGAAGCCGTAGTGGGAGTATTGTGGAACTTATAGCTGGAGGGGGTTCCTCATGCAG CCCTGTCCTTTCAAGAAAACAAAAAGGCAAAGTGCTCTTAGGAGAAGAAGAAGCCTTGGAGGATGACTCTGAATCGAGATCGGATGTCAG CAGCTCTGCCTTAACAGCCTCAGTGAAGGATGAGATCAGTGGAGAGCTGGCTGCTTCTTCAGGGGTTTCCACTCCAGGGTCAGCAGGTCA TGACATCATCACAGAACAGCCACGGTCACAGCACACACTGCAGGCGGACTCAGTGGATCTGGCCAGCTGTGACTTGACAAGCTCTGCCAC TGATGGGGATGAGGAGGATATCTTGAGCCACAGCTCCAGCCAGGTCAGCGCCGTCCCATCTGACCCTGCCATGGACCTGAATGATGGGAC CCAGGCCTCGTCGCCCATCAGCGACAGCTCCCAGACCACCACCGAAGGGCCTGATTCAGCTGTTACCCCTTCAGACAGTTCTGAAATTGT GTTAGACGGTACCGACAACCAGTATTTGGGCCTGCAGATTGGACAGCCCCAGGATGAAGATGAGGAAGCCACAGGTATTCTTCCTGATGA AGCCTCGGAGGCCTTCAGGAACTCTTCCATGGCCCTTCAACAGGCACATTTATTGAAAAACATGAGTCACTGCAGGCAGCCTTCTGACAG CAGTGTTGATAAATTTGTGTTGAGAGATGAAGCTACTGAACCGGGTGATCAAGAAAACAAGCCTTGCCGCATCAAAGGTGACATTGGACA GTCCACTGATGATGACTCTGCACCTCTTGTCCATTGTGTCCGCCTTTTATCTGCTTCGTTTTTGCTAACAGGGGGAAAAAATGTGCTGGT TCCGGACAGGGATGTGAGGGTCAGCGTGAAGGCCCTGGCCCTCAGCTGTGTGGGAGCAGCTGTGGCCCTCCACCCGGAATCTTTCTTCAG CAAACTCTATAAAGTTCCTCTTGACACCACGGAATACCCTGAGGAACAGTATGTCTCAGACATCTTGAACTACATCGATCATGGAGACCC ACAGGTTCGAGGAGCCACTGCCATTCTCTGTGGGACCCTCATCTGCTCCATCCTCAGCAGGTCCCGCTTCCACGTGGGAGATTGGATGGG CACCATTAGAACCCTCACAGGAAATACATTTTCTTTGGCGGATTGCATTCCTTTGCTGCGGAAAACACTGAAGGATGAGTCTTCTGTTAC TTGCAAGTTAGCTTGTACAGCTGTGAGGAACTGTGTCATGAGTCTCTGCAGCAGCAGCTACAGTGAGTTAGGACTGCAGCTGATCATCGA TGTGCTGACTCTGAGGAACAGTTCCTATTGGCTGGTGAGGACAGAGCTTCTGGAAACCCTTGCAGAGATTGACTTCAGGCTGGTGAGCTT TTTGGAGGCAAAAGCAGAAAACTTACACAGAGGGGCTCATCATTATACAGGGCTTTTAAAACTGCAAGAACGAGTGCTCAATAATGTTGT CATCCATTTGCTTGGAGATGAAGACCCCAGGGTGCGACATGTTGCCGCAGCATCACTAATTAGGCTTGTCCCAAAGCTGTTTTATAAATG TGACCAAGGACAAGCTGATCCAGTAGTGGCCGTGGCAAGAGATCAAAGCAGTGTTTACCTGAAACTTCTCATGCATGAGACGCAGCCTCC ATCTCATTTCTCCGTCAGCACAATAACCAGAATATATAGAGGCTATAACCTACTACCAAGCATAACAGACGTCACTATGGAAAATAACCT TTCAAGAGTTATTGCAGCAGTTTCTCATGAACTAATCACATCAACCACCAGAGCACTCACATTTGGATGCTGTGAAGCTTTGTGTCTTCT TTCCACTGCCTTCCCAGTTTGCATTTGGAGTTTAGGTTGGCACTGTGGAGTGCCTCCACTGAGTGCCTCAGATGAGTCTAGGAAGAGCTG TACCGTTGGGATGGCCACAATGATTCTGACCCTGCTCTCGTCAGCTTGGTTCCCATTGGATCTCTCAGCCCATCAAGATGCTTTGATTTT GGCCGGAAACTTGCTTGCAGCCAGTGCTCCCAAATCTCTGAGAAGTTCATGGGCCTCTGAAGAAGAAGCCAACCCAGCAGCCACCAAGCA AGAGGAGGTCTGGCCAGCCCTGGGGGACCGGGCCCTGGTGCCCATGGTGGAGCAGCTCTTCTCTCACCTGCTGAAGGTGATTAACATTTG TGCCCACGTCCTGGATGACGTGGCTCCTGGACCCGCAATAAAGGCAGCCTTGCCTTCTCTAACAAACCCCCCTTCTCTAAGTCCCATCCG ACGAAAGGGGAAGGAGAAAGAACCAGGAGAACAAGCATCTGTACCGTTGAGTCCCAAGAAAGGCAGTGAGGCCAGTGCAGCTTCTAGACA ATCTGATACCTCAGGTCCTGTTACAACAAGTAAATCCTCATCACTGGGGAGTTTCTATCATCTTCCTTCATACCTCAAACTGCATGATGT CCTGAAAGCTACACACGCTAACTACAAGGTCACGCTGGATCTTCAGAACAGCACGGAAAAGTTTGGAGGGTTTCTCCGCTCAGCCTTGGA TGTTCTTTCTCAGATACTAGAGCTGGCCACACTGCAGGACATTGGGAAGTGTGTTGAAGAGATCCTAGGATACCTGAAATCCTGCTTTAG TCGAGAACCAATGATGGCAACTGTTTGTGTTCAACAATTGTTGAAGACTCTCTTTGGCACAAACTTGGCCTCCCAGTTTGATGGCTTATC TTCCAACCCCAGCAAGTCACAAGGCCGAGCACAGCGCCTTGGCTCCTCCAGTGTGAGGCCAGGCTTGTACCACTACTGCTTCATGGCCCC GTACACCCACTTCACCCAGGCCCTCGCTGACGCCAGCCTGAGGAACATGGTGCAGGCGGAGCAGGAGAACGACACCTCGGGATGGTTTGA TGTCCTCCAGAAAGTGTCTACCCAGTTGAAGACAAACCTCACGAGTGTCACAAAGAACCGTGCAGATAAGAATGCTATTCATAATCACAT TCGTTTGTTTGAACCTCTTGTTATAAAAGCTTTAAAACAGTACACGACTACAACATGTGTGCAGTTACAGAAGCAGGTTTTAGATTTGCT GGCGCAGCTGGTTCAGTTACGGGTTAATTACTGTCTTCTGGATTCAGATCAGGTGTTTATTGGCTTTGTATTGAAACAGTTTGAATACAT TGAAGTGGGCCAGTTCAGGGAATCAGAGGCAATCATTCCAAACATCTTTTTCTTCTTGGTATTACTATCTTATGAACGCTATCATTCAAA ACAGATCATTGGAATTCCTAAAATCATTCAGCTCTGTGATGGCATCATGGCCAGTGGAAGGAAGGCTGTGACACATGCCATACCGGCTCT GCAGCCCATAGTCCACGACCTCTTTGTATTAAGAGGAACAAATAAAGCTGATGCAGGAAAAGAGCTTGAAACCCAAAAAGAGGTGGTGGT GTCAATGTTACTGAGACTCATCCAGTACCATCAGGTGTTGGAGATGTTCATTCTTGTCCTGCAGCAGTGCCACAAGGAGAATGAAGACAA GTGGAAGCGACTGTCTCGACAGATAGCTGACATCATCCTCCCAATGTTAGCCAAACAGCAGATGCACATTGACTCTCATGAAGCCCTTGG AGTGTTAAATACATTATTTGAGATTTTGGCCCCTTCCTCCCTCCGTCCGGTAGACATGCTTTTACGGAGTATGTTCGTCACTCCAAACAC AATGGCGTCCGTGAGCACTGTTCAACTGTGGATATCGGGAATTCTGGCCATTTTGAGGGTTCTGATTTCCCAGTCAACTGAAGATATTGT TCTTTCTCGTATTCAGGAGCTCTCCTTCTCTCCGTATTTAATCTCCTGTACAGTAATTAATAGGTTAAGAGATGGGGACAGTACTTCAAC GCTAGAAGAACACAGTGAAGGGAAACAAATAAAGAATTTGCCAGAAGAAACATTTTCAAGGTTTCTATTACAACTGGTTGGTATTCTTTT AGAAGACATTGTTACAAAACAGCTGAAGGTGGAAATGAGTGAGCAGCAACATACTTTCTATTGCCAGGAACTAGGCACACTGCTAATGTG TCTGATCCACATCTTCAAGTCTGGTTCTGAAGACACTACTAATGAAGACTATCAAAGCATTGCCTTATACTTTGAAGGAGAAAAGAGATA TCTTCAGGCTGGAAAATTCTTCTTGCTGTGTGGCCAATATTCACGAGCACTTAAACACTTCCTGAAATGCCCAAGCTCGGAAGATAATGT GGCAATAGAAATGGCAATTGAAACTGTTGGTCAGGCCAAAGATGAACTGCTGACCAATCAGCTGATAGACCATCTCCTGGGGGAGAACGA TGGCATGCCTAAGGATGCCAAGTACCTGTTCCGCTTGTACATGGCTCTGAAGCAATACCGAGAAGCTGCCCAGACTGCCATCATCATTGC CAGAGAAGAGCAGTCTGCAGGCAACTACCGGAATGCACACGATGTTCTCTTCAGTATGTATGCAGAACTGAAATCCCAGAAGATCAAAAT TCCCTCCGAGATGGCCACCAACCTCATGATTCTGCACAGCTATATACTAGTAAAGATTCATGTTAAAAATGGAGATCACATGAAAGGGGC TCGCATGCTCATTCGGGTGGCCAACAACATCAGCAAATTTCCATCACACATTGTACCCATCCTGACGTCAACTGTGATTGAGTGTCACAG GGCAGGCCTGAAGAACTCTGCTTTCAGCTTCGCAGCTATGTTGATGAGGCCTGAATACCGCAGCAAAATAGATGCCAAATACAAAAAGAA GATCGAGGGAATGGTCAGGAGACCCGATATATCTGAGATAGAAGAGGCCACGACTCCATGTCCATTCTGCAAATTTCTTCTCCCAGAGTG TGAACTCCTCTGTCCTGGATGTAAAAACAGTATCCCATATTGCATTGCAACAGGTCGACACATGTTGAAAGATGACTGGACGGTGTGTCC ACATTGTGACTTCCCTGCTCTATACTCAGAATTGAAGATCATGCTAAACACTGAAAGCACATGTCCTATGTGTTCAGAAAGATTAAACGC TGCTCAGCTGAAAAAGATTTCAGACTGTACCCAGTACCTGCGAACGGAGGAGGAACTGTGATTGGCACGTGCAGATACAATGCTCCTGAG AAGACAGCATTTTCCACAGGAGGCTGTTTCCTCCCCTGGTGGATTTAAGAGACGGTCCTTTCTGGATACAGAGAAATGAAACAACGGTGA CCTCTCCAGGTCGGCACTTTCCACTTCTGTACGGTGGCAAAACGATGACATGTAACCTTGCTGTTTATTGTACTTTGTATATTATTTCCT CTTCAAAGTCTTTCTTACACACTCTATCCTCTGCACTGTTAATAGTAACCTATGACATAATTGTAAATATTCAGCTTTTTGCTAACTTTT |
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FusionGenePPI for HTT_WDR19 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| HTT | SETD2, HAP1, ZDHHC17, HYPK, TRIP10, NEUROD1, PRPF40A, PRPF40B, MAGEA3, FICD, UBE2K, AP2A2, OPTN, HYPM, CREBBP, SH3GL3, SP1, MAP3K10, HIP1, EGFR, GRB2, RASA1, TCERG1, TP53, PACSIN1, F8A1, NCOR1, CTBP1, AGO2, KAT2B, SYVN1, AMFR, VCP, CHUK, IKBKB, HSPA8, TRAF6, UBQLN1, IKBKG, AXIN1, CTNNB1, GAPDH, SIAH1, MED31, CRMP1, FEZ1, GIT1, CHD3, ECH1, IKBKAP, XRCC6, PFN2, PIAS4, GPRASP2, UTP14A, DNALI1, GRM1, HSP90AB1, DNAJB1, DNAJA1, HBS1L, TUBA1A, TUBB, PSMC5, ATG5, SQSTM1, NBR1, MAP1LC3A, HTT, TAF4, PIAS1, ZNF451, HOXC4, EVL, UBAC1, HMG20A, ERCC6L, FTL, TTC23, RNF20, HEY2, ZNF655, PIK3R1, ZFYVE19, GOLPH3L, MAGEB18, MRFAP1, UBE2E3, ZMAT2, DUSP10, MRFAP1L1, GGA2, ING5, IFT20, HEYL, TACC1, MBD4, DPPA4, ETV4, MAGEB6, MED21, HIST1H3H, PEX11B, MBD1, TRAFD1, HOXC11, OSTF1, NUPL1, XAGE3, PTGES2, MIPEP, PSMB7, NME4, RPL4, ZFC3H1, UPF3A, CCDC126, HMGA1, FAM71F1, RCN2, USP8, MGRN1, PML, ITCH, USP14, MID1, RPS6KB1, PPP2CA, CREB1, HLA-B, PRMT2, ULK1, RFXANK, LLGL1, MAPK3, KIF23, BAG3, RAPGEF2, HUWE1, MORC3, UBQLN2, RAB30, SNX21, SYT12, MPP1, NPY2R, OPRM1, CRYL1, IL17RA, C5AR2, TKT, RHEB, MTOR | WDR19 | C11orf74, IFT122, DDX39A, IFT43, TULP3, DNAJC7, TULP2, TKT, RAD51D, LRRC27, C6orf141, DOCK5, IFT140, WDR35, PISD, NIPSNAP1, TTC21B, PFKP, NTPCR, SCO1, ACSL3, NEK7 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| Hgene | HTT | chr4:3190820 | chr4:39257468 | ENST00000355072 | + | 40 | 67 | 491_502 | 1789 | 3143 | ZDHHC17 |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for HTT_WDR19 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for HTT_WDR19 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | HTT | C0020179 | Huntington Disease | 9 | CTD_human;ORPHANET |
| Hgene | HTT | C0011570 | Mental Depression | 4 | PSYGENET |
| Hgene | HTT | C0011581 | Depressive disorder | 4 | HPO;PSYGENET |
| Hgene | HTT | C0525045 | Mood Disorders | 2 | PSYGENET |
| Hgene | HTT | C0006635 | Cadmium poisoning | 1 | CTD_human |
| Hgene | HTT | C0026650 | Movement Disorders | 1 | CTD_human;HPO |
| Hgene | HTT | C0677050 | Manganese Poisoning | 1 | CTD_human |
| Tgene | WDR19 | C3280616 | CRANIOECTODERMAL DYSPLASIA 4 | 2 | UNIPROT |
| Tgene | WDR19 | C4225376 | SENIOR-LOKEN SYNDROME 8 | 2 | UNIPROT |
| Tgene | WDR19 | C3280598 | SHORT-RIB THORACIC DYSPLASIA 5 WITH OR WITHOUT POLYDACTYLY | 1 | UNIPROT |
| Tgene | WDR19 | C3280612 | NEPHRONOPHTHISIS 13 | 1 | UNIPROT |
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