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Fusion gene ID: 16567 |
FusionGeneSummary for HNRNPD_PRKG2 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: HNRNPD_PRKG2 | Fusion gene ID: 16567 | Hgene | Tgene | Gene symbol | HNRNPD | PRKG2 | Gene ID | 3184 | 5593 |
| Gene name | heterogeneous nuclear ribonucleoprotein D | protein kinase cGMP-dependent 2 | |
| Synonyms | AUF1|AUF1A|HNRPD|P37|hnRNPD0 | PKG2|PRKGR2|cGK2|cGKII | |
| Cytomap | 4q21.22 | 4q21.21 | |
| Type of gene | protein-coding | protein-coding | |
| Description | heterogeneous nuclear ribonucleoprotein D0ARE-binding protein AUFI, type AAU-rich element RNA binding protein 1, 37kDahnRNP D0 | cGMP-dependent protein kinase 2cGMP-dependent protein kinase IIprotein kinase, cGMP-dependent, type IItesticular tissue protein Li 99 | |
| Modification date | 20180523 | 20180519 | |
| UniProtAcc | Q14103 | Q13237 | |
| Ensembl transtripts involved in fusion gene | ENST00000313899, ENST00000353341, ENST00000543098, ENST00000352301, ENST00000508119, ENST00000541060, | ENST00000264399, ENST00000395578, ENST00000418486, ENST00000545647, ENST00000509169, | |
| Fusion gene scores | * DoF score | 8 X 7 X 4=224 | 1 X 1 X 1=1 |
| # samples | 8 | 1 | |
| ** MAII score | log2(8/224*10)=-1.48542682717024 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(1/1*10)=3.32192809488736 | |
| Context | PubMed: HNRNPD [Title/Abstract] AND PRKG2 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | Kinase involved fusion gene, inframe and retained kinase domain. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | MESO | TCGA-TS-A8AF-01A | HNRNPD | chr4 | 83292681 | - | PRKG2 | chr4 | 82031765 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000313899 | ENST00000264399 | HNRNPD | chr4 | 83292681 | - | PRKG2 | chr4 | 82031765 | - |
| In-frame | ENST00000313899 | ENST00000395578 | HNRNPD | chr4 | 83292681 | - | PRKG2 | chr4 | 82031765 | - |
| In-frame | ENST00000313899 | ENST00000418486 | HNRNPD | chr4 | 83292681 | - | PRKG2 | chr4 | 82031765 | - |
| In-frame | ENST00000313899 | ENST00000545647 | HNRNPD | chr4 | 83292681 | - | PRKG2 | chr4 | 82031765 | - |
| 5CDS-5UTR | ENST00000313899 | ENST00000509169 | HNRNPD | chr4 | 83292681 | - | PRKG2 | chr4 | 82031765 | - |
| In-frame | ENST00000353341 | ENST00000264399 | HNRNPD | chr4 | 83292681 | - | PRKG2 | chr4 | 82031765 | - |
| In-frame | ENST00000353341 | ENST00000395578 | HNRNPD | chr4 | 83292681 | - | PRKG2 | chr4 | 82031765 | - |
| In-frame | ENST00000353341 | ENST00000418486 | HNRNPD | chr4 | 83292681 | - | PRKG2 | chr4 | 82031765 | - |
| In-frame | ENST00000353341 | ENST00000545647 | HNRNPD | chr4 | 83292681 | - | PRKG2 | chr4 | 82031765 | - |
| 5CDS-5UTR | ENST00000353341 | ENST00000509169 | HNRNPD | chr4 | 83292681 | - | PRKG2 | chr4 | 82031765 | - |
| intron-3CDS | ENST00000543098 | ENST00000264399 | HNRNPD | chr4 | 83292681 | - | PRKG2 | chr4 | 82031765 | - |
| intron-3CDS | ENST00000543098 | ENST00000395578 | HNRNPD | chr4 | 83292681 | - | PRKG2 | chr4 | 82031765 | - |
| intron-3CDS | ENST00000543098 | ENST00000418486 | HNRNPD | chr4 | 83292681 | - | PRKG2 | chr4 | 82031765 | - |
| intron-3CDS | ENST00000543098 | ENST00000545647 | HNRNPD | chr4 | 83292681 | - | PRKG2 | chr4 | 82031765 | - |
| intron-5UTR | ENST00000543098 | ENST00000509169 | HNRNPD | chr4 | 83292681 | - | PRKG2 | chr4 | 82031765 | - |
| intron-3CDS | ENST00000352301 | ENST00000264399 | HNRNPD | chr4 | 83292681 | - | PRKG2 | chr4 | 82031765 | - |
| intron-3CDS | ENST00000352301 | ENST00000395578 | HNRNPD | chr4 | 83292681 | - | PRKG2 | chr4 | 82031765 | - |
| intron-3CDS | ENST00000352301 | ENST00000418486 | HNRNPD | chr4 | 83292681 | - | PRKG2 | chr4 | 82031765 | - |
| intron-3CDS | ENST00000352301 | ENST00000545647 | HNRNPD | chr4 | 83292681 | - | PRKG2 | chr4 | 82031765 | - |
| intron-5UTR | ENST00000352301 | ENST00000509169 | HNRNPD | chr4 | 83292681 | - | PRKG2 | chr4 | 82031765 | - |
| intron-3CDS | ENST00000508119 | ENST00000264399 | HNRNPD | chr4 | 83292681 | - | PRKG2 | chr4 | 82031765 | - |
| intron-3CDS | ENST00000508119 | ENST00000395578 | HNRNPD | chr4 | 83292681 | - | PRKG2 | chr4 | 82031765 | - |
| intron-3CDS | ENST00000508119 | ENST00000418486 | HNRNPD | chr4 | 83292681 | - | PRKG2 | chr4 | 82031765 | - |
| intron-3CDS | ENST00000508119 | ENST00000545647 | HNRNPD | chr4 | 83292681 | - | PRKG2 | chr4 | 82031765 | - |
| intron-5UTR | ENST00000508119 | ENST00000509169 | HNRNPD | chr4 | 83292681 | - | PRKG2 | chr4 | 82031765 | - |
| intron-3CDS | ENST00000541060 | ENST00000264399 | HNRNPD | chr4 | 83292681 | - | PRKG2 | chr4 | 82031765 | - |
| intron-3CDS | ENST00000541060 | ENST00000395578 | HNRNPD | chr4 | 83292681 | - | PRKG2 | chr4 | 82031765 | - |
| intron-3CDS | ENST00000541060 | ENST00000418486 | HNRNPD | chr4 | 83292681 | - | PRKG2 | chr4 | 82031765 | - |
| intron-3CDS | ENST00000541060 | ENST00000545647 | HNRNPD | chr4 | 83292681 | - | PRKG2 | chr4 | 82031765 | - |
| intron-5UTR | ENST00000541060 | ENST00000509169 | HNRNPD | chr4 | 83292681 | - | PRKG2 | chr4 | 82031765 | - |
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FusionProtFeatures for HNRNPD_PRKG2 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| HNRNPD | PRKG2 |
| Crucial regulator of intestinal secretion and bonegrowth (By similarity). Phosphorylates and activates CFTR on theplasma membrane. Plays a key role in intestinal secretion byregulating cGMP-dependent translocation of CFTR in jejunum (Bysimilarity). Acts downstream of NMDAR to activate the plasmamembrane accumulation of GRIA1/GLUR1 in synapse and increasesynaptic plasticity. Phosphorylates GRIA1/GLUR1 at Ser-863 (Bysimilarity). Acts as regulator of gene expression and activator ofthe extracellular signal-regulated kinases MAPK3/ERK1 andMAPK1/ERK2 in mechanically stimulated osteoblasts. Under fluidshear stress, mediates ERK activation and subsequent induction ofFOS, FOSL1/FRA1, FOSL2/FRA2 and FOSB that play a key role in theosteoblast anabolic response to mechanical stimulation (Bysimilarity). {ECO:0000250|UniProtKB:Q61410,ECO:0000250|UniProtKB:Q64595}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | HNRNPD | chr4:83292681 | chr4:82031765 | ENST00000313899 | - | 2 | 9 | 11_45 | 96 | 751 | Compositional bias | Note=Ala-rich |
| Hgene | HNRNPD | chr4:83292681 | chr4:82031765 | ENST00000353341 | - | 2 | 8 | 11_45 | 96 | 249 | Compositional bias | Note=Ala-rich |
| Tgene | >PRKG2 | chr4:83292681 | chr4:82031765 | ENST00000264399 | - | 12 | 18 | 712_762 | 592 | 763 | Domain | Note=AGC-kinase C-terminal |
| Tgene | >PRKG2 | chr4:83292681 | chr4:82031765 | ENST00000395578 | - | 13 | 19 | 712_762 | 592 | 763 | Domain | Note=AGC-kinase C-terminal |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >HNRNPD | chr4:83292681 | chr4:82031765 | ENST00000313899 | - | 2 | 9 | 270_347 | 96 | 751 | Compositional bias | Note=Gly-rich |
| Hgene | >HNRNPD | chr4:83292681 | chr4:82031765 | ENST00000313899 | - | 2 | 9 | 294_332 | 96 | 751 | Compositional bias | Note=Tyr-rich |
| Hgene | >HNRNPD | chr4:83292681 | chr4:82031765 | ENST00000352301 | - | 1 | 8 | 11_45 | -102 | 241 | Compositional bias | Note=Ala-rich |
| Hgene | >HNRNPD | chr4:83292681 | chr4:82031765 | ENST00000352301 | - | 1 | 8 | 270_347 | -102 | 241 | Compositional bias | Note=Gly-rich |
| Hgene | >HNRNPD | chr4:83292681 | chr4:82031765 | ENST00000352301 | - | 1 | 8 | 294_332 | -102 | 241 | Compositional bias | Note=Tyr-rich |
| Hgene | >HNRNPD | chr4:83292681 | chr4:82031765 | ENST00000353341 | - | 2 | 8 | 270_347 | 96 | 249 | Compositional bias | Note=Gly-rich |
| Hgene | >HNRNPD | chr4:83292681 | chr4:82031765 | ENST00000353341 | - | 2 | 8 | 294_332 | 96 | 249 | Compositional bias | Note=Tyr-rich |
| Hgene | >HNRNPD | chr4:83292681 | chr4:82031765 | ENST00000313899 | - | 2 | 9 | 182_261 | 96 | 751 | Domain | RRM 2 |
| Hgene | >HNRNPD | chr4:83292681 | chr4:82031765 | ENST00000313899 | - | 2 | 9 | 97_179 | 96 | 751 | Domain | RRM 1 |
| Hgene | >HNRNPD | chr4:83292681 | chr4:82031765 | ENST00000352301 | - | 1 | 8 | 182_261 | -102 | 241 | Domain | RRM 2 |
| Hgene | >HNRNPD | chr4:83292681 | chr4:82031765 | ENST00000352301 | - | 1 | 8 | 97_179 | -102 | 241 | Domain | RRM 1 |
| Hgene | >HNRNPD | chr4:83292681 | chr4:82031765 | ENST00000353341 | - | 2 | 8 | 182_261 | 96 | 249 | Domain | RRM 2 |
| Hgene | >HNRNPD | chr4:83292681 | chr4:82031765 | ENST00000353341 | - | 2 | 8 | 97_179 | 96 | 249 | Domain | RRM 1 |
| Tgene | PRKG2 | chr4:83292681 | chr4:82031765 | ENST00000264399 | - | 12 | 18 | 23_85 | 592 | 763 | Coiled coil | Ontology_term=ECO:0000255 |
| Tgene | PRKG2 | chr4:83292681 | chr4:82031765 | ENST00000395578 | - | 13 | 19 | 23_85 | 592 | 763 | Coiled coil | Ontology_term=ECO:0000255 |
| Tgene | PRKG2 | chr4:83292681 | chr4:82031765 | ENST00000264399 | - | 12 | 18 | 453_711 | 592 | 763 | Domain | Protein kinase |
| Tgene | PRKG2 | chr4:83292681 | chr4:82031765 | ENST00000395578 | - | 13 | 19 | 453_711 | 592 | 763 | Domain | Protein kinase |
| Tgene | PRKG2 | chr4:83292681 | chr4:82031765 | ENST00000264399 | - | 12 | 18 | 232_235 | 592 | 763 | Nucleotide binding | cAMP or cGMP 1 |
| Tgene | PRKG2 | chr4:83292681 | chr4:82031765 | ENST00000264399 | - | 12 | 18 | 242_243 | 592 | 763 | Nucleotide binding | cAMP or cGMP 1 |
| Tgene | PRKG2 | chr4:83292681 | chr4:82031765 | ENST00000264399 | - | 12 | 18 | 357_359 | 592 | 763 | Nucleotide binding | cAMP or cGMP 2 |
| Tgene | PRKG2 | chr4:83292681 | chr4:82031765 | ENST00000264399 | - | 12 | 18 | 366_367 | 592 | 763 | Nucleotide binding | cAMP or cGMP 2 |
| Tgene | PRKG2 | chr4:83292681 | chr4:82031765 | ENST00000264399 | - | 12 | 18 | 459_467 | 592 | 763 | Nucleotide binding | ATP |
| Tgene | PRKG2 | chr4:83292681 | chr4:82031765 | ENST00000395578 | - | 13 | 19 | 232_235 | 592 | 763 | Nucleotide binding | cAMP or cGMP 1 |
| Tgene | PRKG2 | chr4:83292681 | chr4:82031765 | ENST00000395578 | - | 13 | 19 | 242_243 | 592 | 763 | Nucleotide binding | cAMP or cGMP 1 |
| Tgene | PRKG2 | chr4:83292681 | chr4:82031765 | ENST00000395578 | - | 13 | 19 | 357_359 | 592 | 763 | Nucleotide binding | cAMP or cGMP 2 |
| Tgene | PRKG2 | chr4:83292681 | chr4:82031765 | ENST00000395578 | - | 13 | 19 | 366_367 | 592 | 763 | Nucleotide binding | cAMP or cGMP 2 |
| Tgene | PRKG2 | chr4:83292681 | chr4:82031765 | ENST00000395578 | - | 13 | 19 | 459_467 | 592 | 763 | Nucleotide binding | ATP |
| Tgene | PRKG2 | chr4:83292681 | chr4:82031765 | ENST00000264399 | - | 12 | 18 | 168_283 | 592 | 763 | Region | cGMP-binding%2C high affinity%3B cAMP-binding%2C moderate affinity |
| Tgene | PRKG2 | chr4:83292681 | chr4:82031765 | ENST00000264399 | - | 12 | 18 | 286_416 | 592 | 763 | Region | cGMP-binding%2C high affinity%3B cAMP-binding%2C low affinity |
| Tgene | PRKG2 | chr4:83292681 | chr4:82031765 | ENST00000395578 | - | 13 | 19 | 168_283 | 592 | 763 | Region | cGMP-binding%2C high affinity%3B cAMP-binding%2C moderate affinity |
| Tgene | PRKG2 | chr4:83292681 | chr4:82031765 | ENST00000395578 | - | 13 | 19 | 286_416 | 592 | 763 | Region | cGMP-binding%2C high affinity%3B cAMP-binding%2C low affinity |
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FusionGeneSequence for HNRNPD_PRKG2 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_HNRNPD_ENST00000313899_chr4_83292681_-_PRKG2_ENST00000264399_chr4_82031765_-_267aa MSEEQFGGDGAAAAATAAVGGSAGEQEGAMVAATQGAAAAAGSGAGTGGGTASGGTEGGSAESEGAKIDASKNEEDEGHSNSSPRHSEAA TAQREEWLTLDLRRKXGLDRKHGHSVGLQNMXLLKSFSTRDMTSVWISGHWEFXCMSSXRATHPFLGLTKXXPTIXFSKELKKWIFPGRX >In-frame_HNRNPD_ENST00000313899_chr4_83292681_-_PRKG2_ENST00000395578_chr4_82031765_-_267aa MSEEQFGGDGAAAAATAAVGGSAGEQEGAMVAATQGAAAAAGSGAGTGGGTASGGTEGGSAESEGAKIDASKNEEDEGHSNSSPRHSEAA TAQREEWLTLDLRRKXGLDRKHGHSVGLQNMXLLKSFSTRDMTSVWISGHWEFXCMSSXRATHPFLGLTKXXPTIXFSKELKKWIFPGRX >In-frame_HNRNPD_ENST00000313899_chr4_83292681_-_PRKG2_ENST00000418486_chr4_82031765_-_267aa MSEEQFGGDGAAAAATAAVGGSAGEQEGAMVAATQGAAAAAGSGAGTGGGTASGGTEGGSAESEGAKIDASKNEEDEGHSNSSPRHSEAA TAQREEWLTLDLRRKXGLDRKHGHSVGLQNMXLLKSFSTRDMTSVWISGHWEFXCMSSXRATHPFLGLTKXXPTIXFSKELKKWIFPGRX >In-frame_HNRNPD_ENST00000313899_chr4_83292681_-_PRKG2_ENST00000545647_chr4_82031765_-_267aa MSEEQFGGDGAAAAATAAVGGSAGEQEGAMVAATQGAAAAAGSGAGTGGGTASGGTEGGSAESEGAKIDASKNEEDEGHSNSSPRHSEAA TAQREEWLTLDLRRKXGLDRKHGHSVGLQNMXLLKSFSTRDMTSVWISGHWEFXCMSSXRATHPFLGLTKXXPTIXFSKELKKWIFPGRX >In-frame_HNRNPD_ENST00000353341_chr4_83292681_-_PRKG2_ENST00000264399_chr4_82031765_-_267aa MSEEQFGGDGAAAAATAAVGGSAGEQEGAMVAATQGAAAAAGSGAGTGGGTASGGTEGGSAESEGAKIDASKNEEDEGHSNSSPRHSEAA TAQREEWLTLDLRRKXGLDRKHGHSVGLQNMXLLKSFSTRDMTSVWISGHWEFXCMSSXRATHPFLGLTKXXPTIXFSKELKKWIFPGRX >In-frame_HNRNPD_ENST00000353341_chr4_83292681_-_PRKG2_ENST00000395578_chr4_82031765_-_267aa MSEEQFGGDGAAAAATAAVGGSAGEQEGAMVAATQGAAAAAGSGAGTGGGTASGGTEGGSAESEGAKIDASKNEEDEGHSNSSPRHSEAA TAQREEWLTLDLRRKXGLDRKHGHSVGLQNMXLLKSFSTRDMTSVWISGHWEFXCMSSXRATHPFLGLTKXXPTIXFSKELKKWIFPGRX >In-frame_HNRNPD_ENST00000353341_chr4_83292681_-_PRKG2_ENST00000418486_chr4_82031765_-_267aa MSEEQFGGDGAAAAATAAVGGSAGEQEGAMVAATQGAAAAAGSGAGTGGGTASGGTEGGSAESEGAKIDASKNEEDEGHSNSSPRHSEAA TAQREEWLTLDLRRKXGLDRKHGHSVGLQNMXLLKSFSTRDMTSVWISGHWEFXCMSSXRATHPFLGLTKXXPTIXFSKELKKWIFPGRX >In-frame_HNRNPD_ENST00000353341_chr4_83292681_-_PRKG2_ENST00000545647_chr4_82031765_-_267aa MSEEQFGGDGAAAAATAAVGGSAGEQEGAMVAATQGAAAAAGSGAGTGGGTASGGTEGGSAESEGAKIDASKNEEDEGHSNSSPRHSEAA TAQREEWLTLDLRRKXGLDRKHGHSVGLQNMXLLKSFSTRDMTSVWISGHWEFXCMSSXRATHPFLGLTKXXPTIXFSKELKKWIFPGRX |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_HNRNPD_ENST00000313899_chr4_83292681_-_PRKG2_ENST00000264399_chr4_82031765_-_803nt ATGTCGGAGGAGCAGTTCGGCGGGGACGGGGCGGCGGCAGCGGCAACGGCGGCGGTAGGCGGCTCGGCGGGCGAGCAGGAGGGAGCCATG GTGGCGGCGACACAGGGGGCAGCGGCGGCGGCGGGAAGCGGAGCCGGGACCGGGGGCGGAACCGCGTCTGGAGGCACCGAAGGGGGCAGC GCCGAGTCGGAGGGGGCGAAGATTGACGCCAGTAAGAACGAGGAGGATGAAGGCCATTCAAACTCCTCCCCACGACACTCTGAAGCAGCG ACGGCACAGCGGGAAGAATGGTTGACTTTGGATTTGCGAAGAAAATAGGGTCTGGACAGAAAACATGGACATTCTGTGGGACTCCAGAAT ATGTAGCTCCTGAAGTCATTCTCAACAAGGGACATGACTTCAGTGTGGATTTCTGGTCACTGGGAATTCTAGTGTATGAGCTCCTAACGG GCAACCCACCCTTTTCTGGGGTTGACCAAATGATGACCTACAATTTGATTCTCAAAGGAATTGAAAAAATGGATTTTCCCAGGAAGATAA CACGACGACCTGAGGATTTGATTCGGAGGCTTTGCAGGCAAAATCCAACAGAAAGGCTGGGAAATCTGAAGAATGGAATAAATGACATTA AGAAACACAGGTGGTTAAATGGTTTTAATTGGGAGGGACTGAAAGCACGGAGCCTTCCATCACCTTTGCAAAGAGAGCTCAAGGGACCCA >In-frame_HNRNPD_ENST00000313899_chr4_83292681_-_PRKG2_ENST00000395578_chr4_82031765_-_803nt ATGTCGGAGGAGCAGTTCGGCGGGGACGGGGCGGCGGCAGCGGCAACGGCGGCGGTAGGCGGCTCGGCGGGCGAGCAGGAGGGAGCCATG GTGGCGGCGACACAGGGGGCAGCGGCGGCGGCGGGAAGCGGAGCCGGGACCGGGGGCGGAACCGCGTCTGGAGGCACCGAAGGGGGCAGC GCCGAGTCGGAGGGGGCGAAGATTGACGCCAGTAAGAACGAGGAGGATGAAGGCCATTCAAACTCCTCCCCACGACACTCTGAAGCAGCG ACGGCACAGCGGGAAGAATGGTTGACTTTGGATTTGCGAAGAAAATAGGGTCTGGACAGAAAACATGGACATTCTGTGGGACTCCAGAAT ATGTAGCTCCTGAAGTCATTCTCAACAAGGGACATGACTTCAGTGTGGATTTCTGGTCACTGGGAATTCTAGTGTATGAGCTCCTAACGG GCAACCCACCCTTTTCTGGGGTTGACCAAATGATGACCTACAATTTGATTCTCAAAGGAATTGAAAAAATGGATTTTCCCAGGAAGATAA CACGACGACCTGAGGATTTGATTCGGAGGCTTTGCAGGCAAAATCCAACAGAAAGGCTGGGAAATCTGAAGAATGGAATAAATGACATTA AGAAACACAGGTGGTTAAATGGTTTTAATTGGGAGGGACTGAAAGCACGGAGCCTTCCATCACCTTTGCAAAGAGAGCTCAAGGGACCCA >In-frame_HNRNPD_ENST00000313899_chr4_83292681_-_PRKG2_ENST00000418486_chr4_82031765_-_803nt ATGTCGGAGGAGCAGTTCGGCGGGGACGGGGCGGCGGCAGCGGCAACGGCGGCGGTAGGCGGCTCGGCGGGCGAGCAGGAGGGAGCCATG GTGGCGGCGACACAGGGGGCAGCGGCGGCGGCGGGAAGCGGAGCCGGGACCGGGGGCGGAACCGCGTCTGGAGGCACCGAAGGGGGCAGC GCCGAGTCGGAGGGGGCGAAGATTGACGCCAGTAAGAACGAGGAGGATGAAGGCCATTCAAACTCCTCCCCACGACACTCTGAAGCAGCG ACGGCACAGCGGGAAGAATGGTTGACTTTGGATTTGCGAAGAAAATAGGGTCTGGACAGAAAACATGGACATTCTGTGGGACTCCAGAAT ATGTAGCTCCTGAAGTCATTCTCAACAAGGGACATGACTTCAGTGTGGATTTCTGGTCACTGGGAATTCTAGTGTATGAGCTCCTAACGG GCAACCCACCCTTTTCTGGGGTTGACCAAATGATGACCTACAATTTGATTCTCAAAGGAATTGAAAAAATGGATTTTCCCAGGAAGATAA CACGACGACCTGAGGATTTGATTCGGAGGCTTTGCAGGCAAAATCCAACAGAAAGGCTGGGAAATCTGAAGAATGGAATAAATGACATTA AGAAACACAGGTGGTTAAATGGTTTTAATTGGGAGGGACTGAAAGCACGGAGCCTTCCATCACCTTTGCAAAGAGAGCTCAAGGGACCCA >In-frame_HNRNPD_ENST00000313899_chr4_83292681_-_PRKG2_ENST00000545647_chr4_82031765_-_803nt ATGTCGGAGGAGCAGTTCGGCGGGGACGGGGCGGCGGCAGCGGCAACGGCGGCGGTAGGCGGCTCGGCGGGCGAGCAGGAGGGAGCCATG GTGGCGGCGACACAGGGGGCAGCGGCGGCGGCGGGAAGCGGAGCCGGGACCGGGGGCGGAACCGCGTCTGGAGGCACCGAAGGGGGCAGC GCCGAGTCGGAGGGGGCGAAGATTGACGCCAGTAAGAACGAGGAGGATGAAGGCCATTCAAACTCCTCCCCACGACACTCTGAAGCAGCG ACGGCACAGCGGGAAGAATGGTTGACTTTGGATTTGCGAAGAAAATAGGGTCTGGACAGAAAACATGGACATTCTGTGGGACTCCAGAAT ATGTAGCTCCTGAAGTCATTCTCAACAAGGGACATGACTTCAGTGTGGATTTCTGGTCACTGGGAATTCTAGTGTATGAGCTCCTAACGG GCAACCCACCCTTTTCTGGGGTTGACCAAATGATGACCTACAATTTGATTCTCAAAGGAATTGAAAAAATGGATTTTCCCAGGAAGATAA CACGACGACCTGAGGATTTGATTCGGAGGCTTTGCAGGCAAAATCCAACAGAAAGGCTGGGAAATCTGAAGAATGGAATAAATGACATTA AGAAACACAGGTGGTTAAATGGTTTTAATTGGGAGGGACTGAAAGCACGGAGCCTTCCATCACCTTTGCAAAGAGAGCTCAAGGGACCCA >In-frame_HNRNPD_ENST00000353341_chr4_83292681_-_PRKG2_ENST00000264399_chr4_82031765_-_803nt ATGTCGGAGGAGCAGTTCGGCGGGGACGGGGCGGCGGCAGCGGCAACGGCGGCGGTAGGCGGCTCGGCGGGCGAGCAGGAGGGAGCCATG GTGGCGGCGACACAGGGGGCAGCGGCGGCGGCGGGAAGCGGAGCCGGGACCGGGGGCGGAACCGCGTCTGGAGGCACCGAAGGGGGCAGC GCCGAGTCGGAGGGGGCGAAGATTGACGCCAGTAAGAACGAGGAGGATGAAGGCCATTCAAACTCCTCCCCACGACACTCTGAAGCAGCG ACGGCACAGCGGGAAGAATGGTTGACTTTGGATTTGCGAAGAAAATAGGGTCTGGACAGAAAACATGGACATTCTGTGGGACTCCAGAAT ATGTAGCTCCTGAAGTCATTCTCAACAAGGGACATGACTTCAGTGTGGATTTCTGGTCACTGGGAATTCTAGTGTATGAGCTCCTAACGG GCAACCCACCCTTTTCTGGGGTTGACCAAATGATGACCTACAATTTGATTCTCAAAGGAATTGAAAAAATGGATTTTCCCAGGAAGATAA CACGACGACCTGAGGATTTGATTCGGAGGCTTTGCAGGCAAAATCCAACAGAAAGGCTGGGAAATCTGAAGAATGGAATAAATGACATTA AGAAACACAGGTGGTTAAATGGTTTTAATTGGGAGGGACTGAAAGCACGGAGCCTTCCATCACCTTTGCAAAGAGAGCTCAAGGGACCCA >In-frame_HNRNPD_ENST00000353341_chr4_83292681_-_PRKG2_ENST00000395578_chr4_82031765_-_803nt ATGTCGGAGGAGCAGTTCGGCGGGGACGGGGCGGCGGCAGCGGCAACGGCGGCGGTAGGCGGCTCGGCGGGCGAGCAGGAGGGAGCCATG GTGGCGGCGACACAGGGGGCAGCGGCGGCGGCGGGAAGCGGAGCCGGGACCGGGGGCGGAACCGCGTCTGGAGGCACCGAAGGGGGCAGC GCCGAGTCGGAGGGGGCGAAGATTGACGCCAGTAAGAACGAGGAGGATGAAGGCCATTCAAACTCCTCCCCACGACACTCTGAAGCAGCG ACGGCACAGCGGGAAGAATGGTTGACTTTGGATTTGCGAAGAAAATAGGGTCTGGACAGAAAACATGGACATTCTGTGGGACTCCAGAAT ATGTAGCTCCTGAAGTCATTCTCAACAAGGGACATGACTTCAGTGTGGATTTCTGGTCACTGGGAATTCTAGTGTATGAGCTCCTAACGG GCAACCCACCCTTTTCTGGGGTTGACCAAATGATGACCTACAATTTGATTCTCAAAGGAATTGAAAAAATGGATTTTCCCAGGAAGATAA CACGACGACCTGAGGATTTGATTCGGAGGCTTTGCAGGCAAAATCCAACAGAAAGGCTGGGAAATCTGAAGAATGGAATAAATGACATTA AGAAACACAGGTGGTTAAATGGTTTTAATTGGGAGGGACTGAAAGCACGGAGCCTTCCATCACCTTTGCAAAGAGAGCTCAAGGGACCCA >In-frame_HNRNPD_ENST00000353341_chr4_83292681_-_PRKG2_ENST00000418486_chr4_82031765_-_803nt ATGTCGGAGGAGCAGTTCGGCGGGGACGGGGCGGCGGCAGCGGCAACGGCGGCGGTAGGCGGCTCGGCGGGCGAGCAGGAGGGAGCCATG GTGGCGGCGACACAGGGGGCAGCGGCGGCGGCGGGAAGCGGAGCCGGGACCGGGGGCGGAACCGCGTCTGGAGGCACCGAAGGGGGCAGC GCCGAGTCGGAGGGGGCGAAGATTGACGCCAGTAAGAACGAGGAGGATGAAGGCCATTCAAACTCCTCCCCACGACACTCTGAAGCAGCG ACGGCACAGCGGGAAGAATGGTTGACTTTGGATTTGCGAAGAAAATAGGGTCTGGACAGAAAACATGGACATTCTGTGGGACTCCAGAAT ATGTAGCTCCTGAAGTCATTCTCAACAAGGGACATGACTTCAGTGTGGATTTCTGGTCACTGGGAATTCTAGTGTATGAGCTCCTAACGG GCAACCCACCCTTTTCTGGGGTTGACCAAATGATGACCTACAATTTGATTCTCAAAGGAATTGAAAAAATGGATTTTCCCAGGAAGATAA CACGACGACCTGAGGATTTGATTCGGAGGCTTTGCAGGCAAAATCCAACAGAAAGGCTGGGAAATCTGAAGAATGGAATAAATGACATTA AGAAACACAGGTGGTTAAATGGTTTTAATTGGGAGGGACTGAAAGCACGGAGCCTTCCATCACCTTTGCAAAGAGAGCTCAAGGGACCCA >In-frame_HNRNPD_ENST00000353341_chr4_83292681_-_PRKG2_ENST00000545647_chr4_82031765_-_803nt ATGTCGGAGGAGCAGTTCGGCGGGGACGGGGCGGCGGCAGCGGCAACGGCGGCGGTAGGCGGCTCGGCGGGCGAGCAGGAGGGAGCCATG GTGGCGGCGACACAGGGGGCAGCGGCGGCGGCGGGAAGCGGAGCCGGGACCGGGGGCGGAACCGCGTCTGGAGGCACCGAAGGGGGCAGC GCCGAGTCGGAGGGGGCGAAGATTGACGCCAGTAAGAACGAGGAGGATGAAGGCCATTCAAACTCCTCCCCACGACACTCTGAAGCAGCG ACGGCACAGCGGGAAGAATGGTTGACTTTGGATTTGCGAAGAAAATAGGGTCTGGACAGAAAACATGGACATTCTGTGGGACTCCAGAAT ATGTAGCTCCTGAAGTCATTCTCAACAAGGGACATGACTTCAGTGTGGATTTCTGGTCACTGGGAATTCTAGTGTATGAGCTCCTAACGG GCAACCCACCCTTTTCTGGGGTTGACCAAATGATGACCTACAATTTGATTCTCAAAGGAATTGAAAAAATGGATTTTCCCAGGAAGATAA CACGACGACCTGAGGATTTGATTCGGAGGCTTTGCAGGCAAAATCCAACAGAAAGGCTGGGAAATCTGAAGAATGGAATAAATGACATTA AGAAACACAGGTGGTTAAATGGTTTTAATTGGGAGGGACTGAAAGCACGGAGCCTTCCATCACCTTTGCAAAGAGAGCTCAAGGGACCCA |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_HNRNPD_ENST00000313899_chr4_83292681_-_PRKG2_ENST00000264399_chr4_82031765_-_2106nt AAAGCGAGGAGGAGGCGAGAGCGGCCGCCGCTGGTGCTTATTCTTTTTTAGTGCAGCGGGAGAGAGCGGGAGTGTGCGCCGCGCGAGAGT GGGAGGCGAAGGGGGCAGGCCAGGGAGAGGCGCAGGAGCCTTTGCAGCCACGCGCGCGCCTTCCCTGTCTTGTGTGCTTCGCGAGGTAGA GCGGGCGCGCGGCAGCGGCGGGGATTACTTTGCTGCTAGTTTCGGTTCGCGGCAGCGGCGGGTGTAGTCTCGGCGGCAGCGGCGGAGACA CTAGCACTATGTCGGAGGAGCAGTTCGGCGGGGACGGGGCGGCGGCAGCGGCAACGGCGGCGGTAGGCGGCTCGGCGGGCGAGCAGGAGG GAGCCATGGTGGCGGCGACACAGGGGGCAGCGGCGGCGGCGGGAAGCGGAGCCGGGACCGGGGGCGGAACCGCGTCTGGAGGCACCGAAG GGGGCAGCGCCGAGTCGGAGGGGGCGAAGATTGACGCCAGTAAGAACGAGGAGGATGAAGGCCATTCAAACTCCTCCCCACGACACTCTG AAGCAGCGACGGCACAGCGGGAAGAATGGTTGACTTTGGATTTGCGAAGAAAATAGGGTCTGGACAGAAAACATGGACATTCTGTGGGAC TCCAGAATATGTAGCTCCTGAAGTCATTCTCAACAAGGGACATGACTTCAGTGTGGATTTCTGGTCACTGGGAATTCTAGTGTATGAGCT CCTAACGGGCAACCCACCCTTTTCTGGGGTTGACCAAATGATGACCTACAATTTGATTCTCAAAGGAATTGAAAAAATGGATTTTCCCAG GAAGATAACACGACGACCTGAGGATTTGATTCGGAGGCTTTGCAGGCAAAATCCAACAGAAAGGCTGGGAAATCTGAAGAATGGAATAAA TGACATTAAGAAACACAGGTGGTTAAATGGTTTTAATTGGGAGGGACTGAAAGCACGGAGCCTTCCATCACCTTTGCAAAGAGAGCTCAA GGGACCCATAGATCACAGCTACTTTGACAAATATCCTCCTGAAAAGGGAATGCCTCCAGATGAGCTATCAGGCTGGGATAAAGACTTCTG ACAGAAGAAAAGTTGATTACTGCCTGTACTCTACAGAAGAGGACCTCAAGGATCAATAATCCAACACATTATTTTCTTTTCAGAGTATTA TAATATCTTTGGAAGACCATTAGGGAAAAGAAATTCCTGCACAATGGGAAGAGGAGAATGGTGTGGATATGGTTCTGAGTTATAGTGTCT TATTTAGATGCTGTGAATTATTGATGTATTACATTATTTGCTTTTCTCAACTGCTAGAGGCTACCCCATTTTCCTTTCCACAATCAGAGC CATTTTTGTTAAAGTGGCAGTTTTTTCTGCAATCTATTGTTCCATTCCAATCATATCCTTCTCGTTTGAGTACTACTAACGTTTAAAAAG GGTCTTGCCCTTGAATAACTAAGTCATACAAATAGAAGGAAAAACAATGGTGAATTTTGGAGAGCTCCCCAGCTCTCAGCAACTTCATAT AAGCATGGTGGTATCTTAAAATGGTGGTTTGCAGAAACCATGGTAGCCAACAGAACCTCCTGACTTTCACCTGCTTTTAACCTGAAAATA TATTAATACGCCTCTGACATGAGTCCAGGGAGAGGCAAGATTGAGCAATAGTCAGTGGCACCATTTCCTAAAGTAACTGAATCAATCAAT CCAGTCAGGTAATTATTTTCTATTGGGGAACTTAGAAAAAAAAGTAAAGCAAGAAATATTTTCTCTCCTTTATGATCAGTGATACCTTAG AGACTTTTCGAAAGTCCTTGTTAAAGATAGTTACAATGTGTGGTTAAATGATGCTAAAATATTTTCACAACCAGAGTAGAAAACGTGCTG GAACAAAATTGCGAAGGCTTTTGCCTCCCAGTAAATAGAAAGGAAAATATATTCTAGTAGGTAAGACTGCTGACTCTTTGAAAATCTGAG GTATTTTGAAAAATTCTGTGATAGTTGCTATTAATAAACCAAAATTGTATAGAATCATCGTTAATTTTTAATATAAATCCCATTGACAAA >In-frame_HNRNPD_ENST00000313899_chr4_83292681_-_PRKG2_ENST00000395578_chr4_82031765_-_2106nt AAAGCGAGGAGGAGGCGAGAGCGGCCGCCGCTGGTGCTTATTCTTTTTTAGTGCAGCGGGAGAGAGCGGGAGTGTGCGCCGCGCGAGAGT GGGAGGCGAAGGGGGCAGGCCAGGGAGAGGCGCAGGAGCCTTTGCAGCCACGCGCGCGCCTTCCCTGTCTTGTGTGCTTCGCGAGGTAGA GCGGGCGCGCGGCAGCGGCGGGGATTACTTTGCTGCTAGTTTCGGTTCGCGGCAGCGGCGGGTGTAGTCTCGGCGGCAGCGGCGGAGACA CTAGCACTATGTCGGAGGAGCAGTTCGGCGGGGACGGGGCGGCGGCAGCGGCAACGGCGGCGGTAGGCGGCTCGGCGGGCGAGCAGGAGG GAGCCATGGTGGCGGCGACACAGGGGGCAGCGGCGGCGGCGGGAAGCGGAGCCGGGACCGGGGGCGGAACCGCGTCTGGAGGCACCGAAG GGGGCAGCGCCGAGTCGGAGGGGGCGAAGATTGACGCCAGTAAGAACGAGGAGGATGAAGGCCATTCAAACTCCTCCCCACGACACTCTG AAGCAGCGACGGCACAGCGGGAAGAATGGTTGACTTTGGATTTGCGAAGAAAATAGGGTCTGGACAGAAAACATGGACATTCTGTGGGAC TCCAGAATATGTAGCTCCTGAAGTCATTCTCAACAAGGGACATGACTTCAGTGTGGATTTCTGGTCACTGGGAATTCTAGTGTATGAGCT CCTAACGGGCAACCCACCCTTTTCTGGGGTTGACCAAATGATGACCTACAATTTGATTCTCAAAGGAATTGAAAAAATGGATTTTCCCAG GAAGATAACACGACGACCTGAGGATTTGATTCGGAGGCTTTGCAGGCAAAATCCAACAGAAAGGCTGGGAAATCTGAAGAATGGAATAAA TGACATTAAGAAACACAGGTGGTTAAATGGTTTTAATTGGGAGGGACTGAAAGCACGGAGCCTTCCATCACCTTTGCAAAGAGAGCTCAA GGGACCCATAGATCACAGCTACTTTGACAAATATCCTCCTGAAAAGGGAATGCCTCCAGATGAGCTATCAGGCTGGGATAAAGACTTCTG ACAGAAGAAAAGTTGATTACTGCCTGTACTCTACAGAAGAGGACCTCAAGGATCAATAATCCAACACATTATTTTCTTTTCAGAGTATTA TAATATCTTTGGAAGACCATTAGGGAAAAGAAATTCCTGCACAATGGGAAGAGGAGAATGGTGTGGATATGGTTCTGAGTTATAGTGTCT TATTTAGATGCTGTGAATTATTGATGTATTACATTATTTGCTTTTCTCAACTGCTAGAGGCTACCCCATTTTCCTTTCCACAATCAGAGC CATTTTTGTTAAAGTGGCAGTTTTTTCTGCAATCTATTGTTCCATTCCAATCATATCCTTCTCGTTTGAGTACTACTAACGTTTAAAAAG GGTCTTGCCCTTGAATAACTAAGTCATACAAATAGAAGGAAAAACAATGGTGAATTTTGGAGAGCTCCCCAGCTCTCAGCAACTTCATAT AAGCATGGTGGTATCTTAAAATGGTGGTTTGCAGAAACCATGGTAGCCAACAGAACCTCCTGACTTTCACCTGCTTTTAACCTGAAAATA TATTAATACGCCTCTGACATGAGTCCAGGGAGAGGCAAGATTGAGCAATAGTCAGTGGCACCATTTCCTAAAGTAACTGAATCAATCAAT CCAGTCAGGTAATTATTTTCTATTGGGGAACTTAGAAAAAAAAGTAAAGCAAGAAATATTTTCTCTCCTTTATGATCAGTGATACCTTAG AGACTTTTCGAAAGTCCTTGTTAAAGATAGTTACAATGTGTGGTTAAATGATGCTAAAATATTTTCACAACCAGAGTAGAAAACGTGCTG GAACAAAATTGCGAAGGCTTTTGCCTCCCAGTAAATAGAAAGGAAAATATATTCTAGTAGGTAAGACTGCTGACTCTTTGAAAATCTGAG GTATTTTGAAAAATTCTGTGATAGTTGCTATTAATAAACCAAAATTGTATAGAATCATCGTTAATTTTTAATATAAATCCCATTGACAAA >In-frame_HNRNPD_ENST00000313899_chr4_83292681_-_PRKG2_ENST00000418486_chr4_82031765_-_1360nt AAAGCGAGGAGGAGGCGAGAGCGGCCGCCGCTGGTGCTTATTCTTTTTTAGTGCAGCGGGAGAGAGCGGGAGTGTGCGCCGCGCGAGAGT GGGAGGCGAAGGGGGCAGGCCAGGGAGAGGCGCAGGAGCCTTTGCAGCCACGCGCGCGCCTTCCCTGTCTTGTGTGCTTCGCGAGGTAGA GCGGGCGCGCGGCAGCGGCGGGGATTACTTTGCTGCTAGTTTCGGTTCGCGGCAGCGGCGGGTGTAGTCTCGGCGGCAGCGGCGGAGACA CTAGCACTATGTCGGAGGAGCAGTTCGGCGGGGACGGGGCGGCGGCAGCGGCAACGGCGGCGGTAGGCGGCTCGGCGGGCGAGCAGGAGG GAGCCATGGTGGCGGCGACACAGGGGGCAGCGGCGGCGGCGGGAAGCGGAGCCGGGACCGGGGGCGGAACCGCGTCTGGAGGCACCGAAG GGGGCAGCGCCGAGTCGGAGGGGGCGAAGATTGACGCCAGTAAGAACGAGGAGGATGAAGGCCATTCAAACTCCTCCCCACGACACTCTG AAGCAGCGACGGCACAGCGGGAAGAATGGTTGACTTTGGATTTGCGAAGAAAATAGGGTCTGGACAGAAAACATGGACATTCTGTGGGAC TCCAGAATATGTAGCTCCTGAAGTCATTCTCAACAAGGGACATGACTTCAGTGTGGATTTCTGGTCACTGGGAATTCTAGTGTATGAGCT CCTAACGGGCAACCCACCCTTTTCTGGGGTTGACCAAATGATGACCTACAATTTGATTCTCAAAGGAATTGAAAAAATGGATTTTCCCAG GAAGATAACACGACGACCTGAGGATTTGATTCGGAGGCTTTGCAGGCAAAATCCAACAGAAAGGCTGGGAAATCTGAAGAATGGAATAAA TGACATTAAGAAACACAGGTGGTTAAATGGTTTTAATTGGGAGGGACTGAAAGCACGGAGCCTTCCATCACCTTTGCAAAGAGAGCTCAA GGGACCCATAGATCACAGCTACTTTGACAAATATCCTCCTGAAAAGGGAATGCCTCCAGATGAGCTATCAGGCTGGGATAAAGACTTCTG ACAGAAGAAAAGTTGATTACTGCCTGTACTCTACAGAAGAGGACCTCAAGGATCAATAATCCAACACATTATTTTCTTTTCAGAGTATTA TAATATCTTTGGAAGACCATTAGGGAAAAGAAATTCCTGCACAATGGGAAGAGGAGAATGGTGTGGATATGGTTCTGAGTTATAGTGTCT TATTTAGATGCTGTGAATTATTGATGTATTACATTATTTGCTTTTCTCAACTGCTAGAGGCTACCCCATTTTCCTTTCCACAATCAGAGC >In-frame_HNRNPD_ENST00000313899_chr4_83292681_-_PRKG2_ENST00000545647_chr4_82031765_-_1296nt AAAGCGAGGAGGAGGCGAGAGCGGCCGCCGCTGGTGCTTATTCTTTTTTAGTGCAGCGGGAGAGAGCGGGAGTGTGCGCCGCGCGAGAGT GGGAGGCGAAGGGGGCAGGCCAGGGAGAGGCGCAGGAGCCTTTGCAGCCACGCGCGCGCCTTCCCTGTCTTGTGTGCTTCGCGAGGTAGA GCGGGCGCGCGGCAGCGGCGGGGATTACTTTGCTGCTAGTTTCGGTTCGCGGCAGCGGCGGGTGTAGTCTCGGCGGCAGCGGCGGAGACA CTAGCACTATGTCGGAGGAGCAGTTCGGCGGGGACGGGGCGGCGGCAGCGGCAACGGCGGCGGTAGGCGGCTCGGCGGGCGAGCAGGAGG GAGCCATGGTGGCGGCGACACAGGGGGCAGCGGCGGCGGCGGGAAGCGGAGCCGGGACCGGGGGCGGAACCGCGTCTGGAGGCACCGAAG GGGGCAGCGCCGAGTCGGAGGGGGCGAAGATTGACGCCAGTAAGAACGAGGAGGATGAAGGCCATTCAAACTCCTCCCCACGACACTCTG AAGCAGCGACGGCACAGCGGGAAGAATGGTTGACTTTGGATTTGCGAAGAAAATAGGGTCTGGACAGAAAACATGGACATTCTGTGGGAC TCCAGAATATGTAGCTCCTGAAGTCATTCTCAACAAGGGACATGACTTCAGTGTGGATTTCTGGTCACTGGGAATTCTAGTGTATGAGCT CCTAACGGGCAACCCACCCTTTTCTGGGGTTGACCAAATGATGACCTACAATTTGATTCTCAAAGGAATTGAAAAAATGGATTTTCCCAG GAAGATAACACGACGACCTGAGGATTTGATTCGGAGGCTTTGCAGGCAAAATCCAACAGAAAGGCTGGGAAATCTGAAGAATGGAATAAA TGACATTAAGAAACACAGGTGGTTAAATGGTTTTAATTGGGAGGGACTGAAAGCACGGAGCCTTCCATCACCTTTGCAAAGAGAGCTCAA GGGACCCATAGATCACAGCTACTTTGACAAATATCCTCCTGAAAAGGGAATGCCTCCAGATGAGCTATCAGGCTGGGATAAAGACTTCTG ACAGAAGAAAAGTTGATTACTGCCTGTACTCTACAGAAGAGGACCTCAAGGATCAATAATCCAACACATTATTTTCTTTTCAGAGTATTA TAATATCTTTGGAAGACCATTAGGGAAAAGAAATTCCTGCACAATGGGAAGAGGAGAATGGTGTGGATATGGTTCTGAGTTATAGTGTCT >In-frame_HNRNPD_ENST00000353341_chr4_83292681_-_PRKG2_ENST00000264399_chr4_82031765_-_2136nt CCATTTTAGGTGGTCCGCGGCGGCGCCATTAAAGCGAGGAGGAGGCGAGAGCGGCCGCCGCTGGTGCTTATTCTTTTTTAGTGCAGCGGG AGAGAGCGGGAGTGTGCGCCGCGCGAGAGTGGGAGGCGAAGGGGGCAGGCCAGGGAGAGGCGCAGGAGCCTTTGCAGCCACGCGCGCGCC TTCCCTGTCTTGTGTGCTTCGCGAGGTAGAGCGGGCGCGCGGCAGCGGCGGGGATTACTTTGCTGCTAGTTTCGGTTCGCGGCAGCGGCG GGTGTAGTCTCGGCGGCAGCGGCGGAGACACTAGCACTATGTCGGAGGAGCAGTTCGGCGGGGACGGGGCGGCGGCAGCGGCAACGGCGG CGGTAGGCGGCTCGGCGGGCGAGCAGGAGGGAGCCATGGTGGCGGCGACACAGGGGGCAGCGGCGGCGGCGGGAAGCGGAGCCGGGACCG GGGGCGGAACCGCGTCTGGAGGCACCGAAGGGGGCAGCGCCGAGTCGGAGGGGGCGAAGATTGACGCCAGTAAGAACGAGGAGGATGAAG GCCATTCAAACTCCTCCCCACGACACTCTGAAGCAGCGACGGCACAGCGGGAAGAATGGTTGACTTTGGATTTGCGAAGAAAATAGGGTC TGGACAGAAAACATGGACATTCTGTGGGACTCCAGAATATGTAGCTCCTGAAGTCATTCTCAACAAGGGACATGACTTCAGTGTGGATTT CTGGTCACTGGGAATTCTAGTGTATGAGCTCCTAACGGGCAACCCACCCTTTTCTGGGGTTGACCAAATGATGACCTACAATTTGATTCT CAAAGGAATTGAAAAAATGGATTTTCCCAGGAAGATAACACGACGACCTGAGGATTTGATTCGGAGGCTTTGCAGGCAAAATCCAACAGA AAGGCTGGGAAATCTGAAGAATGGAATAAATGACATTAAGAAACACAGGTGGTTAAATGGTTTTAATTGGGAGGGACTGAAAGCACGGAG CCTTCCATCACCTTTGCAAAGAGAGCTCAAGGGACCCATAGATCACAGCTACTTTGACAAATATCCTCCTGAAAAGGGAATGCCTCCAGA TGAGCTATCAGGCTGGGATAAAGACTTCTGACAGAAGAAAAGTTGATTACTGCCTGTACTCTACAGAAGAGGACCTCAAGGATCAATAAT CCAACACATTATTTTCTTTTCAGAGTATTATAATATCTTTGGAAGACCATTAGGGAAAAGAAATTCCTGCACAATGGGAAGAGGAGAATG GTGTGGATATGGTTCTGAGTTATAGTGTCTTATTTAGATGCTGTGAATTATTGATGTATTACATTATTTGCTTTTCTCAACTGCTAGAGG CTACCCCATTTTCCTTTCCACAATCAGAGCCATTTTTGTTAAAGTGGCAGTTTTTTCTGCAATCTATTGTTCCATTCCAATCATATCCTT CTCGTTTGAGTACTACTAACGTTTAAAAAGGGTCTTGCCCTTGAATAACTAAGTCATACAAATAGAAGGAAAAACAATGGTGAATTTTGG AGAGCTCCCCAGCTCTCAGCAACTTCATATAAGCATGGTGGTATCTTAAAATGGTGGTTTGCAGAAACCATGGTAGCCAACAGAACCTCC TGACTTTCACCTGCTTTTAACCTGAAAATATATTAATACGCCTCTGACATGAGTCCAGGGAGAGGCAAGATTGAGCAATAGTCAGTGGCA CCATTTCCTAAAGTAACTGAATCAATCAATCCAGTCAGGTAATTATTTTCTATTGGGGAACTTAGAAAAAAAAGTAAAGCAAGAAATATT TTCTCTCCTTTATGATCAGTGATACCTTAGAGACTTTTCGAAAGTCCTTGTTAAAGATAGTTACAATGTGTGGTTAAATGATGCTAAAAT ATTTTCACAACCAGAGTAGAAAACGTGCTGGAACAAAATTGCGAAGGCTTTTGCCTCCCAGTAAATAGAAAGGAAAATATATTCTAGTAG GTAAGACTGCTGACTCTTTGAAAATCTGAGGTATTTTGAAAAATTCTGTGATAGTTGCTATTAATAAACCAAAATTGTATAGAATCATCG >In-frame_HNRNPD_ENST00000353341_chr4_83292681_-_PRKG2_ENST00000395578_chr4_82031765_-_2136nt CCATTTTAGGTGGTCCGCGGCGGCGCCATTAAAGCGAGGAGGAGGCGAGAGCGGCCGCCGCTGGTGCTTATTCTTTTTTAGTGCAGCGGG AGAGAGCGGGAGTGTGCGCCGCGCGAGAGTGGGAGGCGAAGGGGGCAGGCCAGGGAGAGGCGCAGGAGCCTTTGCAGCCACGCGCGCGCC TTCCCTGTCTTGTGTGCTTCGCGAGGTAGAGCGGGCGCGCGGCAGCGGCGGGGATTACTTTGCTGCTAGTTTCGGTTCGCGGCAGCGGCG GGTGTAGTCTCGGCGGCAGCGGCGGAGACACTAGCACTATGTCGGAGGAGCAGTTCGGCGGGGACGGGGCGGCGGCAGCGGCAACGGCGG CGGTAGGCGGCTCGGCGGGCGAGCAGGAGGGAGCCATGGTGGCGGCGACACAGGGGGCAGCGGCGGCGGCGGGAAGCGGAGCCGGGACCG GGGGCGGAACCGCGTCTGGAGGCACCGAAGGGGGCAGCGCCGAGTCGGAGGGGGCGAAGATTGACGCCAGTAAGAACGAGGAGGATGAAG GCCATTCAAACTCCTCCCCACGACACTCTGAAGCAGCGACGGCACAGCGGGAAGAATGGTTGACTTTGGATTTGCGAAGAAAATAGGGTC TGGACAGAAAACATGGACATTCTGTGGGACTCCAGAATATGTAGCTCCTGAAGTCATTCTCAACAAGGGACATGACTTCAGTGTGGATTT CTGGTCACTGGGAATTCTAGTGTATGAGCTCCTAACGGGCAACCCACCCTTTTCTGGGGTTGACCAAATGATGACCTACAATTTGATTCT CAAAGGAATTGAAAAAATGGATTTTCCCAGGAAGATAACACGACGACCTGAGGATTTGATTCGGAGGCTTTGCAGGCAAAATCCAACAGA AAGGCTGGGAAATCTGAAGAATGGAATAAATGACATTAAGAAACACAGGTGGTTAAATGGTTTTAATTGGGAGGGACTGAAAGCACGGAG CCTTCCATCACCTTTGCAAAGAGAGCTCAAGGGACCCATAGATCACAGCTACTTTGACAAATATCCTCCTGAAAAGGGAATGCCTCCAGA TGAGCTATCAGGCTGGGATAAAGACTTCTGACAGAAGAAAAGTTGATTACTGCCTGTACTCTACAGAAGAGGACCTCAAGGATCAATAAT CCAACACATTATTTTCTTTTCAGAGTATTATAATATCTTTGGAAGACCATTAGGGAAAAGAAATTCCTGCACAATGGGAAGAGGAGAATG GTGTGGATATGGTTCTGAGTTATAGTGTCTTATTTAGATGCTGTGAATTATTGATGTATTACATTATTTGCTTTTCTCAACTGCTAGAGG CTACCCCATTTTCCTTTCCACAATCAGAGCCATTTTTGTTAAAGTGGCAGTTTTTTCTGCAATCTATTGTTCCATTCCAATCATATCCTT CTCGTTTGAGTACTACTAACGTTTAAAAAGGGTCTTGCCCTTGAATAACTAAGTCATACAAATAGAAGGAAAAACAATGGTGAATTTTGG AGAGCTCCCCAGCTCTCAGCAACTTCATATAAGCATGGTGGTATCTTAAAATGGTGGTTTGCAGAAACCATGGTAGCCAACAGAACCTCC TGACTTTCACCTGCTTTTAACCTGAAAATATATTAATACGCCTCTGACATGAGTCCAGGGAGAGGCAAGATTGAGCAATAGTCAGTGGCA CCATTTCCTAAAGTAACTGAATCAATCAATCCAGTCAGGTAATTATTTTCTATTGGGGAACTTAGAAAAAAAAGTAAAGCAAGAAATATT TTCTCTCCTTTATGATCAGTGATACCTTAGAGACTTTTCGAAAGTCCTTGTTAAAGATAGTTACAATGTGTGGTTAAATGATGCTAAAAT ATTTTCACAACCAGAGTAGAAAACGTGCTGGAACAAAATTGCGAAGGCTTTTGCCTCCCAGTAAATAGAAAGGAAAATATATTCTAGTAG GTAAGACTGCTGACTCTTTGAAAATCTGAGGTATTTTGAAAAATTCTGTGATAGTTGCTATTAATAAACCAAAATTGTATAGAATCATCG >In-frame_HNRNPD_ENST00000353341_chr4_83292681_-_PRKG2_ENST00000418486_chr4_82031765_-_1390nt CCATTTTAGGTGGTCCGCGGCGGCGCCATTAAAGCGAGGAGGAGGCGAGAGCGGCCGCCGCTGGTGCTTATTCTTTTTTAGTGCAGCGGG AGAGAGCGGGAGTGTGCGCCGCGCGAGAGTGGGAGGCGAAGGGGGCAGGCCAGGGAGAGGCGCAGGAGCCTTTGCAGCCACGCGCGCGCC TTCCCTGTCTTGTGTGCTTCGCGAGGTAGAGCGGGCGCGCGGCAGCGGCGGGGATTACTTTGCTGCTAGTTTCGGTTCGCGGCAGCGGCG GGTGTAGTCTCGGCGGCAGCGGCGGAGACACTAGCACTATGTCGGAGGAGCAGTTCGGCGGGGACGGGGCGGCGGCAGCGGCAACGGCGG CGGTAGGCGGCTCGGCGGGCGAGCAGGAGGGAGCCATGGTGGCGGCGACACAGGGGGCAGCGGCGGCGGCGGGAAGCGGAGCCGGGACCG GGGGCGGAACCGCGTCTGGAGGCACCGAAGGGGGCAGCGCCGAGTCGGAGGGGGCGAAGATTGACGCCAGTAAGAACGAGGAGGATGAAG GCCATTCAAACTCCTCCCCACGACACTCTGAAGCAGCGACGGCACAGCGGGAAGAATGGTTGACTTTGGATTTGCGAAGAAAATAGGGTC TGGACAGAAAACATGGACATTCTGTGGGACTCCAGAATATGTAGCTCCTGAAGTCATTCTCAACAAGGGACATGACTTCAGTGTGGATTT CTGGTCACTGGGAATTCTAGTGTATGAGCTCCTAACGGGCAACCCACCCTTTTCTGGGGTTGACCAAATGATGACCTACAATTTGATTCT CAAAGGAATTGAAAAAATGGATTTTCCCAGGAAGATAACACGACGACCTGAGGATTTGATTCGGAGGCTTTGCAGGCAAAATCCAACAGA AAGGCTGGGAAATCTGAAGAATGGAATAAATGACATTAAGAAACACAGGTGGTTAAATGGTTTTAATTGGGAGGGACTGAAAGCACGGAG CCTTCCATCACCTTTGCAAAGAGAGCTCAAGGGACCCATAGATCACAGCTACTTTGACAAATATCCTCCTGAAAAGGGAATGCCTCCAGA TGAGCTATCAGGCTGGGATAAAGACTTCTGACAGAAGAAAAGTTGATTACTGCCTGTACTCTACAGAAGAGGACCTCAAGGATCAATAAT CCAACACATTATTTTCTTTTCAGAGTATTATAATATCTTTGGAAGACCATTAGGGAAAAGAAATTCCTGCACAATGGGAAGAGGAGAATG GTGTGGATATGGTTCTGAGTTATAGTGTCTTATTTAGATGCTGTGAATTATTGATGTATTACATTATTTGCTTTTCTCAACTGCTAGAGG >In-frame_HNRNPD_ENST00000353341_chr4_83292681_-_PRKG2_ENST00000545647_chr4_82031765_-_1326nt CCATTTTAGGTGGTCCGCGGCGGCGCCATTAAAGCGAGGAGGAGGCGAGAGCGGCCGCCGCTGGTGCTTATTCTTTTTTAGTGCAGCGGG AGAGAGCGGGAGTGTGCGCCGCGCGAGAGTGGGAGGCGAAGGGGGCAGGCCAGGGAGAGGCGCAGGAGCCTTTGCAGCCACGCGCGCGCC TTCCCTGTCTTGTGTGCTTCGCGAGGTAGAGCGGGCGCGCGGCAGCGGCGGGGATTACTTTGCTGCTAGTTTCGGTTCGCGGCAGCGGCG GGTGTAGTCTCGGCGGCAGCGGCGGAGACACTAGCACTATGTCGGAGGAGCAGTTCGGCGGGGACGGGGCGGCGGCAGCGGCAACGGCGG CGGTAGGCGGCTCGGCGGGCGAGCAGGAGGGAGCCATGGTGGCGGCGACACAGGGGGCAGCGGCGGCGGCGGGAAGCGGAGCCGGGACCG GGGGCGGAACCGCGTCTGGAGGCACCGAAGGGGGCAGCGCCGAGTCGGAGGGGGCGAAGATTGACGCCAGTAAGAACGAGGAGGATGAAG GCCATTCAAACTCCTCCCCACGACACTCTGAAGCAGCGACGGCACAGCGGGAAGAATGGTTGACTTTGGATTTGCGAAGAAAATAGGGTC TGGACAGAAAACATGGACATTCTGTGGGACTCCAGAATATGTAGCTCCTGAAGTCATTCTCAACAAGGGACATGACTTCAGTGTGGATTT CTGGTCACTGGGAATTCTAGTGTATGAGCTCCTAACGGGCAACCCACCCTTTTCTGGGGTTGACCAAATGATGACCTACAATTTGATTCT CAAAGGAATTGAAAAAATGGATTTTCCCAGGAAGATAACACGACGACCTGAGGATTTGATTCGGAGGCTTTGCAGGCAAAATCCAACAGA AAGGCTGGGAAATCTGAAGAATGGAATAAATGACATTAAGAAACACAGGTGGTTAAATGGTTTTAATTGGGAGGGACTGAAAGCACGGAG CCTTCCATCACCTTTGCAAAGAGAGCTCAAGGGACCCATAGATCACAGCTACTTTGACAAATATCCTCCTGAAAAGGGAATGCCTCCAGA TGAGCTATCAGGCTGGGATAAAGACTTCTGACAGAAGAAAAGTTGATTACTGCCTGTACTCTACAGAAGAGGACCTCAAGGATCAATAAT CCAACACATTATTTTCTTTTCAGAGTATTATAATATCTTTGGAAGACCATTAGGGAAAAGAAATTCCTGCACAATGGGAAGAGGAGAATG |
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FusionGenePPI for HNRNPD_PRKG2 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| HNRNPD | LSM5, SAFB, TRN-GTT2-1, HSPB1, HSPA4, HSPA8, EIF4G1, HNRNPD, HNRNPH1, CDK9, MEPCE, KHDRBS2, GPN1, BANF1, MTA2, HDAC1, PABPC1, H2AFX, CD4, HDAC5, HSPB2, MAPK6, PCBP1, PCBP2, VHL, SMARCAD1, SREK1, ARRB2, HNRNPA1, PAIP1, BCL2, CUL3, CUL4A, CUL4B, CUL5, CUL2, CDK2, CUL1, COPS5, COPS6, DCUN1D1, CAND1, NEDD8, SYNCRIP, YBX1, IGF2BP2, UBE2I, MEOX2, GRB2, VEGFA, TNF, HNRNPR, PTBP1, RBMX, HNRNPF, HNRNPL, HNRNPA2B1, HNRNPA0, HNRNPA3, MRPL12, RPS28, RALY, HNRNPDL, AHNAK, RMDN3, SEPT9, SLC30A5, DDX1, MSH2, SMURF1, SFN, FN1, VCAM1, SNRPC, SF3B4, U2AF2, HNRNPC, HNRNPU, HNRNPK, HNRNPH3, PTBP2, IFIT2, IFIT3, IL7R, BRCA1, ITGA4, PAN2, CD81, IGSF8, ICAM1, HMGA1, C1QBP, RPSA, ACTB, GTF3C3, CD97, EXOSC4, EEF2, SNAPC4, ABCC10, BET1L, TSEN34, CINP, SHISA5, MPP1, TMEM261, GUK1, P4HB, FLNA, ARF4, SLC3A2, MAP2K1, HIRA, DGCR2, CAPN1, HBZ, PDLIM7, IMMT, PYCR1, SLC27A5, NTMT1, DHX30, CUTA, GTSE1, FBXL15, COL18A1, IMMP2L, COG7, PPOX, CTSB, PEX10, UQCRC1, PRDX3, SDF2, B3GAT3, PARK2, EIF3K, DENR, IPO11, ERI1, PAFAH1B3, KHSRP, RPS12, WNK1, RPA1, RPA2, RPA3, ERG, ASB2, HSPA5, IVNS1ABP, STAU1, NCL, KAT2B, FUS, ING4, MYC, ENO1, MOV10, NXF1, MDM2, CUL7, OBSL1, EED, ESR1, BTRC, FBXW11, PTGS2, CHEK1, DNAJC7, HNRNPAB, AURKA, C2orf49, HSPA9, NAA50, PICALM, PKM, SFPQ, TARS, TOMM34, UBE2G2, PGK1, NTRK1, SCARNA22, EWSR1, BLMH, SLC25A20, CETN2, DKC1, DNM2, ETFA, FANCD2, ACSL4, MTOR, GOLGA4, HEXA, DYNC1H1, HNRNPH2, MYEF2, HSD17B4, HSPA6, ITGB4, EIF6, MAP3K4, MYH1, NHS, PDCL, PLXNB1, PPM1A, RBM4, RET, SRSF6, UAP1, TARBP1, GCFC2, TLN1, TNFRSF1A, BAG6, USP11, DYSF, NRP1, TAX1BP1, FUBP3, GTF2IRD1, ESPL1, ARHGAP32, C2CD5, OSBPL2, RBM8A, PRMT3, SAP18, ABCA7, TUBB3, PPIH, SRSF10, COG2, FNDC3A, MORC2, FAM120A, USP24, KIAA0368, DICER1, SIRT5, KLHDC2, INTS7, PKN3, PNPLA8, CHMP5, UHRF1BP1, RASIP1, PINX1, HEATR3, SMEK2, ZNF286A, GPBP1, PDRG1, SBF2, TLN2, KLF16, OBSCN, WDR24, GPRIN1, MRPL55, PTGR2, PPP1R18, DDX51, HNRNPCL1, MCM2, SNW1, CYLD, TRIM25, UBE2A, HEY1 | PRKG2 | MYLK, NEDD4, HSP90AA1, FBXO25, CDKL5, UNC119, WDR77, PDE9A, NPHP3 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for HNRNPD_PRKG2 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
| Hgene | HNRNPD | Q14103 | DB11638 | Artenimol | Heterogeneous nuclear ribonucleoprotein D0 | small molecule | approved|investigational |
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RelatedDiseases for HNRNPD_PRKG2 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
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