|
||||||
|
 | |
| |
| |
| |
| |
|
Fusion gene ID: 16207 |
FusionGeneSummary for HIPK2_PARP12 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: HIPK2_PARP12 | Fusion gene ID: 16207 | Hgene | Tgene | Gene symbol | HIPK2 | PARP12 | Gene ID | 28996 | 64761 |
| Gene name | homeodomain interacting protein kinase 2 | poly(ADP-ribose) polymerase family member 12 | |
| Synonyms | PRO0593 | ARTD12|MST109|MSTP109|ZC3H1|ZC3HDC1 | |
| Cytomap | 7q34 | 7q34 | |
| Type of gene | protein-coding | protein-coding | |
| Description | homeodomain-interacting protein kinase 2hHIPk2 | poly [ADP-ribose] polymerase 12ADP-ribosyltransferase diphtheria toxin-like 12zinc finger CCCH type domain containing 1 | |
| Modification date | 20180522 | 20180519 | |
| UniProtAcc | Q9H2X6 | Q9H0J9 | |
| Ensembl transtripts involved in fusion gene | ENST00000406875, ENST00000428878, ENST00000342645, | ENST00000263549, ENST00000470515, | |
| Fusion gene scores | * DoF score | 11 X 7 X 9=693 | 3 X 4 X 2=24 |
| # samples | 12 | 4 | |
| ** MAII score | log2(12/693*10)=-2.5298209465287 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(4/24*10)=0.736965594166206 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
| Context | PubMed: HIPK2 [Title/Abstract] AND PARP12 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | Tumor suppressor gene involved fusion gene, in-frame but not retained their domain. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | HIPK2 | GO:0006468 | protein phosphorylation | 19448668 |
| Hgene | HIPK2 | GO:0006978 | DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator | 14647468 |
| Hgene | HIPK2 | GO:0045766 | positive regulation of angiogenesis | 19046997 |
| Hgene | HIPK2 | GO:0060395 | SMAD protein signal transduction | 12874272 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | UCEC | TCGA-A5-A2K4-01A | HIPK2 | chr7 | 139415731 | - | PARP12 | chr7 | 139726148 | - |
| TCGA | RV | UCEC | TCGA-KP-A3W4-01A | HIPK2 | chr7 | 139415731 | - | PARP12 | chr7 | 139728488 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000406875 | ENST00000263549 | HIPK2 | chr7 | 139415731 | - | PARP12 | chr7 | 139726148 | - |
| 5CDS-intron | ENST00000406875 | ENST00000470515 | HIPK2 | chr7 | 139415731 | - | PARP12 | chr7 | 139726148 | - |
| In-frame | ENST00000428878 | ENST00000263549 | HIPK2 | chr7 | 139415731 | - | PARP12 | chr7 | 139726148 | - |
| 5CDS-intron | ENST00000428878 | ENST00000470515 | HIPK2 | chr7 | 139415731 | - | PARP12 | chr7 | 139726148 | - |
| In-frame | ENST00000342645 | ENST00000263549 | HIPK2 | chr7 | 139415731 | - | PARP12 | chr7 | 139726148 | - |
| 5CDS-intron | ENST00000342645 | ENST00000470515 | HIPK2 | chr7 | 139415731 | - | PARP12 | chr7 | 139726148 | - |
| In-frame | ENST00000406875 | ENST00000263549 | HIPK2 | chr7 | 139415731 | - | PARP12 | chr7 | 139728488 | - |
| 5CDS-intron | ENST00000406875 | ENST00000470515 | HIPK2 | chr7 | 139415731 | - | PARP12 | chr7 | 139728488 | - |
| In-frame | ENST00000428878 | ENST00000263549 | HIPK2 | chr7 | 139415731 | - | PARP12 | chr7 | 139728488 | - |
| 5CDS-intron | ENST00000428878 | ENST00000470515 | HIPK2 | chr7 | 139415731 | - | PARP12 | chr7 | 139728488 | - |
| In-frame | ENST00000342645 | ENST00000263549 | HIPK2 | chr7 | 139415731 | - | PARP12 | chr7 | 139728488 | - |
| 5CDS-intron | ENST00000342645 | ENST00000470515 | HIPK2 | chr7 | 139415731 | - | PARP12 | chr7 | 139728488 | - |
Top |
FusionProtFeatures for HIPK2_PARP12 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| HIPK2 | PARP12 |
| Serine/threonine-protein kinase involved intranscription regulation, p53/TP53-mediated cellular apoptosis andregulation of the cell cycle. Acts as a corepressor of severaltranscription factors, including SMAD1 and POU4F1/Brn3a andprobably NK homeodomain transcription factors. PhosphorylatesPDX1, ATF1, PML, p53/TP53, CREB1, CTBP1, CBX4, RUNX1, EP300,CTNNB1, HMGA1 and ZBTB4. Inhibits cell growth and promotesapoptosis through the activation of p53/TP53 both at thetranscription level and at the protein level (by phosphorylationand indirect acetylation). The phosphorylation of p53/TP53 may bemediated by a p53/TP53-HIPK2-AXIN1 complex. Involved in theresponse to hypoxia by acting as a transcriptional co-suppressorof HIF1A. Mediates transcriptional activation of TP73. In responseto TGFB, cooperates with DAXX to activate JNK. Negative regulatorthrough phosphorylation and subsequent proteasomal degradation ofCTNNB1 and the antiapoptotic factor CTBP1. In the Wnt/beta-cateninsignaling pathway acts as an intermediate kinase betweenMAP3K7/TAK1 and NLK to promote the proteasomal degradation of MYB.Phosphorylates CBX4 upon DNA damage and promotes its E3 SUMO-protein ligase activity. Activates CREB1 and ATF1 transcriptionfactors by phosphorylation in response to genotoxic stress. Inresponse to DNA damage, stabilizes PML by phosphorylation. PML,HIPK2 and FBXO3 may act synergically to activate p53/TP53-dependent transactivation. Promotes angiogenesis, and is involvedin erythroid differentiation, especially during fetal livererythropoiesis. Phosphorylation of RUNX1 and EP300 stimulatesEP300 transcription regulation activity. Triggers ZBTB4 proteindegradation in response to DNA damage. Modulates HMGA1 DNA-bindingaffinity. In response to high glucose, triggers phosphorylation-mediated subnuclear localization shifting of PDX1. Involved in theregulation of eye size, lens formation and retinal laminationduring late embryogenesis. {ECO:0000269|PubMed:11740489,ECO:0000269|PubMed:11925430, ECO:0000269|PubMed:12851404,ECO:0000269|PubMed:12874272, ECO:0000269|PubMed:14678985,ECO:0000269|PubMed:17018294, ECO:0000269|PubMed:17960875,ECO:0000269|PubMed:18695000, ECO:0000269|PubMed:18809579,ECO:0000269|PubMed:19015637, ECO:0000269|PubMed:19046997,ECO:0000269|PubMed:19448668, ECO:0000269|PubMed:20307497,ECO:0000269|PubMed:20573984, ECO:0000269|PubMed:20637728,ECO:0000269|PubMed:20980392, ECO:0000269|PubMed:21192925,ECO:0000269|PubMed:22825850}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | HIPK2 | chr7:139415731 | chr7:139726148 | ENST00000406875 | - | 2 | 15 | 205_213 | 367 | 1199 | Nucleotide binding | ATP |
| Hgene | HIPK2 | chr7:139415731 | chr7:139726148 | ENST00000428878 | - | 2 | 15 | 205_213 | 367 | 1172 | Nucleotide binding | ATP |
| Hgene | HIPK2 | chr7:139415731 | chr7:139728488 | ENST00000406875 | - | 2 | 15 | 205_213 | 367 | 1199 | Nucleotide binding | ATP |
| Hgene | HIPK2 | chr7:139415731 | chr7:139728488 | ENST00000428878 | - | 2 | 15 | 205_213 | 367 | 1172 | Nucleotide binding | ATP |
| Hgene | HIPK2 | chr7:139415731 | chr7:139726148 | ENST00000406875 | - | 2 | 15 | 97_230 | 367 | 1199 | Region | Transcriptional corepression |
| Hgene | HIPK2 | chr7:139415731 | chr7:139726148 | ENST00000428878 | - | 2 | 15 | 97_230 | 367 | 1172 | Region | Transcriptional corepression |
| Hgene | HIPK2 | chr7:139415731 | chr7:139728488 | ENST00000406875 | - | 2 | 15 | 97_230 | 367 | 1199 | Region | Transcriptional corepression |
| Hgene | HIPK2 | chr7:139415731 | chr7:139728488 | ENST00000428878 | - | 2 | 15 | 97_230 | 367 | 1172 | Region | Transcriptional corepression |
| Tgene | >PARP12 | chr7:139415731 | chr7:139728488 | ENST00000263549 | - | 7 | 12 | 484_698 | 473 | 702 | Domain | PARP catalytic |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >HIPK2 | chr7:139415731 | chr7:139726148 | ENST00000406875 | - | 2 | 15 | 1088_1094 | 367 | 1199 | Compositional bias | Note=Poly-Ala |
| Hgene | >HIPK2 | chr7:139415731 | chr7:139726148 | ENST00000428878 | - | 2 | 15 | 1088_1094 | 367 | 1172 | Compositional bias | Note=Poly-Ala |
| Hgene | >HIPK2 | chr7:139415731 | chr7:139728488 | ENST00000406875 | - | 2 | 15 | 1088_1094 | 367 | 1199 | Compositional bias | Note=Poly-Ala |
| Hgene | >HIPK2 | chr7:139415731 | chr7:139728488 | ENST00000428878 | - | 2 | 15 | 1088_1094 | 367 | 1172 | Compositional bias | Note=Poly-Ala |
| Hgene | >HIPK2 | chr7:139415731 | chr7:139726148 | ENST00000406875 | - | 2 | 15 | 199_527 | 367 | 1199 | Domain | Protein kinase |
| Hgene | >HIPK2 | chr7:139415731 | chr7:139726148 | ENST00000428878 | - | 2 | 15 | 199_527 | 367 | 1172 | Domain | Protein kinase |
| Hgene | >HIPK2 | chr7:139415731 | chr7:139728488 | ENST00000406875 | - | 2 | 15 | 199_527 | 367 | 1199 | Domain | Protein kinase |
| Hgene | >HIPK2 | chr7:139415731 | chr7:139728488 | ENST00000428878 | - | 2 | 15 | 199_527 | 367 | 1172 | Domain | Protein kinase |
| Hgene | >HIPK2 | chr7:139415731 | chr7:139726148 | ENST00000406875 | - | 2 | 15 | 802_805 | 367 | 1199 | Motif | Note=Nuclear localization signal 1 (NLS1) |
| Hgene | >HIPK2 | chr7:139415731 | chr7:139726148 | ENST00000406875 | - | 2 | 15 | 832_835 | 367 | 1199 | Motif | Note=Nuclear localization signal 2 (NLS2) |
| Hgene | >HIPK2 | chr7:139415731 | chr7:139726148 | ENST00000428878 | - | 2 | 15 | 802_805 | 367 | 1172 | Motif | Note=Nuclear localization signal 1 (NLS1) |
| Hgene | >HIPK2 | chr7:139415731 | chr7:139726148 | ENST00000428878 | - | 2 | 15 | 832_835 | 367 | 1172 | Motif | Note=Nuclear localization signal 2 (NLS2) |
| Hgene | >HIPK2 | chr7:139415731 | chr7:139728488 | ENST00000406875 | - | 2 | 15 | 802_805 | 367 | 1199 | Motif | Note=Nuclear localization signal 1 (NLS1) |
| Hgene | >HIPK2 | chr7:139415731 | chr7:139728488 | ENST00000406875 | - | 2 | 15 | 832_835 | 367 | 1199 | Motif | Note=Nuclear localization signal 2 (NLS2) |
| Hgene | >HIPK2 | chr7:139415731 | chr7:139728488 | ENST00000428878 | - | 2 | 15 | 802_805 | 367 | 1172 | Motif | Note=Nuclear localization signal 1 (NLS1) |
| Hgene | >HIPK2 | chr7:139415731 | chr7:139728488 | ENST00000428878 | - | 2 | 15 | 832_835 | 367 | 1172 | Motif | Note=Nuclear localization signal 2 (NLS2) |
| Hgene | >HIPK2 | chr7:139415731 | chr7:139726148 | ENST00000406875 | - | 2 | 15 | 873_980 | 367 | 1199 | Region | Required for localization to nuclear speckles |
| Hgene | >HIPK2 | chr7:139415731 | chr7:139726148 | ENST00000406875 | - | 2 | 15 | 984_1198 | 367 | 1199 | Region | Note=Autoinhibitory domain (AID) |
| Hgene | >HIPK2 | chr7:139415731 | chr7:139726148 | ENST00000428878 | - | 2 | 15 | 873_980 | 367 | 1172 | Region | Required for localization to nuclear speckles |
| Hgene | >HIPK2 | chr7:139415731 | chr7:139726148 | ENST00000428878 | - | 2 | 15 | 984_1198 | 367 | 1172 | Region | Note=Autoinhibitory domain (AID) |
| Hgene | >HIPK2 | chr7:139415731 | chr7:139728488 | ENST00000406875 | - | 2 | 15 | 873_980 | 367 | 1199 | Region | Required for localization to nuclear speckles |
| Hgene | >HIPK2 | chr7:139415731 | chr7:139728488 | ENST00000406875 | - | 2 | 15 | 984_1198 | 367 | 1199 | Region | Note=Autoinhibitory domain (AID) |
| Hgene | >HIPK2 | chr7:139415731 | chr7:139728488 | ENST00000428878 | - | 2 | 15 | 873_980 | 367 | 1172 | Region | Required for localization to nuclear speckles |
| Hgene | >HIPK2 | chr7:139415731 | chr7:139728488 | ENST00000428878 | - | 2 | 15 | 984_1198 | 367 | 1172 | Region | Note=Autoinhibitory domain (AID) |
| Tgene | PARP12 | chr7:139415731 | chr7:139726148 | ENST00000263549 | - | 9 | 12 | 58_61 | 542 | 702 | Compositional bias | Note=Poly-Ala |
| Tgene | PARP12 | chr7:139415731 | chr7:139728488 | ENST00000263549 | - | 7 | 12 | 58_61 | 473 | 702 | Compositional bias | Note=Poly-Ala |
| Tgene | PARP12 | chr7:139415731 | chr7:139726148 | ENST00000263549 | - | 9 | 12 | 298_361 | 542 | 702 | Domain | WWE 1 |
| Tgene | PARP12 | chr7:139415731 | chr7:139726148 | ENST00000263549 | - | 9 | 12 | 364_458 | 542 | 702 | Domain | WWE 2 |
| Tgene | PARP12 | chr7:139415731 | chr7:139726148 | ENST00000263549 | - | 9 | 12 | 484_698 | 542 | 702 | Domain | PARP catalytic |
| Tgene | PARP12 | chr7:139415731 | chr7:139728488 | ENST00000263549 | - | 7 | 12 | 298_361 | 473 | 702 | Domain | WWE 1 |
| Tgene | PARP12 | chr7:139415731 | chr7:139728488 | ENST00000263549 | - | 7 | 12 | 364_458 | 473 | 702 | Domain | WWE 2 |
| Tgene | PARP12 | chr7:139415731 | chr7:139726148 | ENST00000263549 | - | 9 | 12 | 150_179 | 542 | 702 | Zinc finger | C3H1-type 2 |
| Tgene | PARP12 | chr7:139415731 | chr7:139726148 | ENST00000263549 | - | 9 | 12 | 180_202 | 542 | 702 | Zinc finger | C3H1-type 3 |
| Tgene | PARP12 | chr7:139415731 | chr7:139726148 | ENST00000263549 | - | 9 | 12 | 270_297 | 542 | 702 | Zinc finger | C3H1-type 4 |
| Tgene | PARP12 | chr7:139415731 | chr7:139726148 | ENST00000263549 | - | 9 | 12 | 271_296 | 542 | 702 | Zinc finger | C3H1-type 3 |
| Tgene | PARP12 | chr7:139415731 | chr7:139726148 | ENST00000263549 | - | 9 | 12 | 94_119 | 542 | 702 | Zinc finger | C3H1-type 1 |
| Tgene | PARP12 | chr7:139415731 | chr7:139728488 | ENST00000263549 | - | 7 | 12 | 150_179 | 473 | 702 | Zinc finger | C3H1-type 2 |
| Tgene | PARP12 | chr7:139415731 | chr7:139728488 | ENST00000263549 | - | 7 | 12 | 180_202 | 473 | 702 | Zinc finger | C3H1-type 3 |
| Tgene | PARP12 | chr7:139415731 | chr7:139728488 | ENST00000263549 | - | 7 | 12 | 270_297 | 473 | 702 | Zinc finger | C3H1-type 4 |
| Tgene | PARP12 | chr7:139415731 | chr7:139728488 | ENST00000263549 | - | 7 | 12 | 271_296 | 473 | 702 | Zinc finger | C3H1-type 3 |
| Tgene | PARP12 | chr7:139415731 | chr7:139728488 | ENST00000263549 | - | 7 | 12 | 94_119 | 473 | 702 | Zinc finger | C3H1-type 1 |
Top |
FusionGeneSequence for HIPK2_PARP12 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_HIPK2_ENST00000406875_chr7_139415731_-_PARP12_ENST00000263549_chr7_139728488_-_596aa MAPVYEGMASHVQVFSPHTLQSSAFCSVKKLKIEPSSNWDMTGYGSHSKVYSQSKNIPLSQPATTTVSTSLPVPNPSLPYEQTIVFPGST GHIVVTSASSTSVTGQVLGGPHNLMRRSTVSLLDTYQKCGLKRKSEEIENTSSVQIIEEHPPMIQNNASGATVATATTSTATSKNSGSNS EGDYQLVQHEVLCSMTNTYEVLEFLGRGTFGQVVKCWKRGTNEIVAIKILKNHPSYARQGQIEVSILARLSTESADDYNFVRAYECFQHK NHTCLVFEMLEQNLYDFLKQNKFSPLPLKYIRPVLQQVATALMKLKSLGLIHADLKPENIMLVDPSRQPYRVKVIDFGSASHVSKAVCST YLQSRYYSNTKFPGPKSIPDYWDSSALPDPGFQKITLSSSSEEYQKVWNLFNRTLPFYFVQKIERVQNLALWEVYQWQKGQMQKQNGGKA VDERQLFHGTSAIFVDAICQQNFDWRVCGVHGTSYGKGSYFARDAAYSHHYSKSDTQTHTMFLARVLVGEFVRGNASFVRPPAKEGWSNA >In-frame_HIPK2_ENST00000428878_chr7_139415731_-_PARP12_ENST00000263549_chr7_139728488_-_596aa MAPVYEGMASHVQVFSPHTLQSSAFCSVKKLKIEPSSNWDMTGYGSHSKVYSQSKNIPLSQPATTTVSTSLPVPNPSLPYEQTIVFPGST GHIVVTSASSTSVTGQVLGGPHNLMRRSTVSLLDTYQKCGLKRKSEEIENTSSVQIIEEHPPMIQNNASGATVATATTSTATSKNSGSNS EGDYQLVQHEVLCSMTNTYEVLEFLGRGTFGQVVKCWKRGTNEIVAIKILKNHPSYARQGQIEVSILARLSTESADDYNFVRAYECFQHK NHTCLVFEMLEQNLYDFLKQNKFSPLPLKYIRPVLQQVATALMKLKSLGLIHADLKPENIMLVDPSRQPYRVKVIDFGSASHVSKAVCST YLQSRYYSNTKFPGPKSIPDYWDSSALPDPGFQKITLSSSSEEYQKVWNLFNRTLPFYFVQKIERVQNLALWEVYQWQKGQMQKQNGGKA VDERQLFHGTSAIFVDAICQQNFDWRVCGVHGTSYGKGSYFARDAAYSHHYSKSDTQTHTMFLARVLVGEFVRGNASFVRPPAKEGWSNA >In-frame_HIPK2_ENST00000342645_chr7_139415731_-_PARP12_ENST00000263549_chr7_139728488_-_596aa LQPVYESMASHVQVFSPHTLQSSAFCSVKKLKIEPSSNWDMTGYGSHSKVYSQSKNIPLSQPATTTVSTSLPVPNPSLPYEQTIVFPGST GHIVVTSASSTSVTGQVLGGPHNLMRRSTVSLLDTYQKCGLKRKSEEIENTSSVQIIEEHPPMIQNNASGATVATATTSTATSKNSGSNS EGDYQLVQHEVLCSMTNTYEVLEFLGRGTFGQVVKCWKRGTNEIVAIKILKNHPSYARQGQIEVSILARLSTESADDYNFVRAYECFQHK NHTCLVFEMLEQNLYDFLKQNKFSPLPLKYIRPVLQQVATALMKLKSLGLIHADLKPENIMLVDPSRQPYRVKVIDFGSASHVSKAVCST YLQSRYYSNTKFPGPKSIPDYWDSSALPDPGFQKITLSSSSEEYQKVWNLFNRTLPFYFVQKIERVQNLALWEVYQWQKGQMQKQNGGKA VDERQLFHGTSAIFVDAICQQNFDWRVCGVHGTSYGKGSYFARDAAYSHHYSKSDTQTHTMFLARVLVGEFVRGNASFVRPPAKEGWSNA >In-frame_HIPK2_ENST00000406875_chr7_139415731_-_PARP12_ENST00000263549_chr7_139726148_-_527aa MAPVYEGMASHVQVFSPHTLQSSAFCSVKKLKIEPSSNWDMTGYGSHSKVYSQSKNIPLSQPATTTVSTSLPVPNPSLPYEQTIVFPGST GHIVVTSASSTSVTGQVLGGPHNLMRRSTVSLLDTYQKCGLKRKSEEIENTSSVQIIEEHPPMIQNNASGATVATATTSTATSKNSGSNS EGDYQLVQHEVLCSMTNTYEVLEFLGRGTFGQVVKCWKRGTNEIVAIKILKNHPSYARQGQIEVSILARLSTESADDYNFVRAYECFQHK NHTCLVFEMLEQNLYDFLKQNKFSPLPLKYIRPVLQQVATALMKLKSLGLIHADLKPENIMLVDPSRQPYRVKVIDFGSASHVSKAVCST YLQSRYYRQKGQMQKQNGGKAVDERQLFHGTSAIFVDAICQQNFDWRVCGVHGTSYGKGSYFARDAAYSHHYSKSDTQTHTMFLARVLVG >In-frame_HIPK2_ENST00000428878_chr7_139415731_-_PARP12_ENST00000263549_chr7_139726148_-_527aa MAPVYEGMASHVQVFSPHTLQSSAFCSVKKLKIEPSSNWDMTGYGSHSKVYSQSKNIPLSQPATTTVSTSLPVPNPSLPYEQTIVFPGST GHIVVTSASSTSVTGQVLGGPHNLMRRSTVSLLDTYQKCGLKRKSEEIENTSSVQIIEEHPPMIQNNASGATVATATTSTATSKNSGSNS EGDYQLVQHEVLCSMTNTYEVLEFLGRGTFGQVVKCWKRGTNEIVAIKILKNHPSYARQGQIEVSILARLSTESADDYNFVRAYECFQHK NHTCLVFEMLEQNLYDFLKQNKFSPLPLKYIRPVLQQVATALMKLKSLGLIHADLKPENIMLVDPSRQPYRVKVIDFGSASHVSKAVCST YLQSRYYRQKGQMQKQNGGKAVDERQLFHGTSAIFVDAICQQNFDWRVCGVHGTSYGKGSYFARDAAYSHHYSKSDTQTHTMFLARVLVG >In-frame_HIPK2_ENST00000342645_chr7_139415731_-_PARP12_ENST00000263549_chr7_139726148_-_527aa LQPVYESMASHVQVFSPHTLQSSAFCSVKKLKIEPSSNWDMTGYGSHSKVYSQSKNIPLSQPATTTVSTSLPVPNPSLPYEQTIVFPGST GHIVVTSASSTSVTGQVLGGPHNLMRRSTVSLLDTYQKCGLKRKSEEIENTSSVQIIEEHPPMIQNNASGATVATATTSTATSKNSGSNS EGDYQLVQHEVLCSMTNTYEVLEFLGRGTFGQVVKCWKRGTNEIVAIKILKNHPSYARQGQIEVSILARLSTESADDYNFVRAYECFQHK NHTCLVFEMLEQNLYDFLKQNKFSPLPLKYIRPVLQQVATALMKLKSLGLIHADLKPENIMLVDPSRQPYRVKVIDFGSASHVSKAVCST YLQSRYYRQKGQMQKQNGGKAVDERQLFHGTSAIFVDAICQQNFDWRVCGVHGTSYGKGSYFARDAAYSHHYSKSDTQTHTMFLARVLVG |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_HIPK2_ENST00000406875_chr7_139415731_-_PARP12_ENST00000263549_chr7_139728488_-_1788nt ATGGCCCCCGTGTACGAAGGTATGGCCTCACATGTGCAAGTTTTCTCCCCTCACACCCTTCAATCAAGTGCCTTCTGTAGTGTGAAGAAA CTGAAAATAGAGCCGAGTTCCAACTGGGACATGACTGGGTACGGCTCCCACAGCAAAGTGTATAGCCAGAGCAAGAACATCCCCCTGTCG CAGCCAGCCACCACAACCGTCAGCACCTCCTTGCCGGTCCCAAACCCAAGCCTACCTTACGAGCAGACCATCGTCTTCCCAGGAAGCACC GGGCACATCGTGGTCACCTCAGCAAGCAGCACTTCTGTCACCGGGCAAGTCCTCGGCGGACCACACAACCTAATGCGTCGAAGCACTGTG AGCCTCCTTGATACCTACCAAAAATGTGGACTCAAGCGTAAGAGCGAGGAGATCGAGAACACAAGCAGCGTGCAGATCATCGAGGAGCAT CCACCCATGATTCAGAATAATGCAAGCGGGGCCACTGTCGCCACTGCCACCACGTCTACTGCCACCTCCAAAAACAGCGGCTCCAACAGC GAGGGCGACTATCAGCTGGTGCAGCATGAGGTGCTGTGCTCCATGACCAACACCTACGAGGTCTTAGAGTTCTTGGGCCGAGGGACGTTT GGGCAAGTGGTCAAGTGCTGGAAACGGGGCACCAATGAGATCGTAGCCATCAAGATCCTGAAGAACCACCCATCCTATGCCCGACAAGGT CAGATTGAAGTGAGCATCCTGGCCCGGTTGAGCACGGAGAGTGCCGATGACTATAACTTCGTCCGGGCCTACGAATGCTTCCAGCACAAG AACCACACGTGCTTGGTCTTCGAGATGTTGGAGCAGAACCTCTATGACTTTCTGAAGCAAAACAAGTTTAGCCCCTTGCCCCTCAAATAC ATTCGCCCAGTTCTCCAGCAGGTAGCCACAGCCCTGATGAAACTCAAAAGCCTAGGTCTTATCCACGCTGACCTCAAACCAGAAAACATC ATGCTGGTGGATCCATCTAGACAACCATACAGAGTCAAGGTCATCGACTTTGGTTCAGCCAGCCACGTCTCCAAGGCTGTGTGCTCCACC TACTTGCAGTCCAGATATTACAGCAATACCAAGTTTCCAGGCCCGAAGAGCATCCCAGACTATTGGGACTCCTCTGCCCTGCCAGACCCA GGCTTTCAGAAGATCACCCTTAGTTCTTCCTCGGAAGAGTATCAGAAGGTCTGGAACCTCTTTAACCGCACGCTGCCTTTCTACTTTGTT CAGAAGATTGAGCGAGTACAGAACCTGGCCCTCTGGGAAGTCTACCAGTGGCAAAAAGGACAGATGCAGAAGCAGAACGGAGGGAAGGCC GTGGACGAGCGGCAGCTGTTCCACGGCACCAGCGCCATTTTTGTGGACGCCATCTGCCAGCAGAACTTTGACTGGCGGGTCTGTGGTGTT CATGGCACTTCCTACGGCAAGGGGAGCTACTTTGCCCGAGATGCTGCATATTCCCACCACTACAGCAAATCCGACACGCAGACCCACACG ATGTTCCTGGCCCGGGTGCTGGTGGGCGAGTTCGTCAGGGGCAATGCCTCCTTTGTCCGTCCGCCGGCCAAGGAGGGCTGGAGCAACGCC TTCTATGATAGCTGCGTGAACAGTGTGTCCGACCCCTCCATCTTTGTGATCTTTGAGAAACACCAGGTCTACCCAGAGTATGTCATCCAG >In-frame_HIPK2_ENST00000428878_chr7_139415731_-_PARP12_ENST00000263549_chr7_139728488_-_1788nt ATGGCCCCCGTGTACGAAGGTATGGCCTCACATGTGCAAGTTTTCTCCCCTCACACCCTTCAATCAAGTGCCTTCTGTAGTGTGAAGAAA CTGAAAATAGAGCCGAGTTCCAACTGGGACATGACTGGGTACGGCTCCCACAGCAAAGTGTATAGCCAGAGCAAGAACATCCCCCTGTCG CAGCCAGCCACCACAACCGTCAGCACCTCCTTGCCGGTCCCAAACCCAAGCCTACCTTACGAGCAGACCATCGTCTTCCCAGGAAGCACC GGGCACATCGTGGTCACCTCAGCAAGCAGCACTTCTGTCACCGGGCAAGTCCTCGGCGGACCACACAACCTAATGCGTCGAAGCACTGTG AGCCTCCTTGATACCTACCAAAAATGTGGACTCAAGCGTAAGAGCGAGGAGATCGAGAACACAAGCAGCGTGCAGATCATCGAGGAGCAT CCACCCATGATTCAGAATAATGCAAGCGGGGCCACTGTCGCCACTGCCACCACGTCTACTGCCACCTCCAAAAACAGCGGCTCCAACAGC GAGGGCGACTATCAGCTGGTGCAGCATGAGGTGCTGTGCTCCATGACCAACACCTACGAGGTCTTAGAGTTCTTGGGCCGAGGGACGTTT GGGCAAGTGGTCAAGTGCTGGAAACGGGGCACCAATGAGATCGTAGCCATCAAGATCCTGAAGAACCACCCATCCTATGCCCGACAAGGT CAGATTGAAGTGAGCATCCTGGCCCGGTTGAGCACGGAGAGTGCCGATGACTATAACTTCGTCCGGGCCTACGAATGCTTCCAGCACAAG AACCACACGTGCTTGGTCTTCGAGATGTTGGAGCAGAACCTCTATGACTTTCTGAAGCAAAACAAGTTTAGCCCCTTGCCCCTCAAATAC ATTCGCCCAGTTCTCCAGCAGGTAGCCACAGCCCTGATGAAACTCAAAAGCCTAGGTCTTATCCACGCTGACCTCAAACCAGAAAACATC ATGCTGGTGGATCCATCTAGACAACCATACAGAGTCAAGGTCATCGACTTTGGTTCAGCCAGCCACGTCTCCAAGGCTGTGTGCTCCACC TACTTGCAGTCCAGATATTACAGCAATACCAAGTTTCCAGGCCCGAAGAGCATCCCAGACTATTGGGACTCCTCTGCCCTGCCAGACCCA GGCTTTCAGAAGATCACCCTTAGTTCTTCCTCGGAAGAGTATCAGAAGGTCTGGAACCTCTTTAACCGCACGCTGCCTTTCTACTTTGTT CAGAAGATTGAGCGAGTACAGAACCTGGCCCTCTGGGAAGTCTACCAGTGGCAAAAAGGACAGATGCAGAAGCAGAACGGAGGGAAGGCC GTGGACGAGCGGCAGCTGTTCCACGGCACCAGCGCCATTTTTGTGGACGCCATCTGCCAGCAGAACTTTGACTGGCGGGTCTGTGGTGTT CATGGCACTTCCTACGGCAAGGGGAGCTACTTTGCCCGAGATGCTGCATATTCCCACCACTACAGCAAATCCGACACGCAGACCCACACG ATGTTCCTGGCCCGGGTGCTGGTGGGCGAGTTCGTCAGGGGCAATGCCTCCTTTGTCCGTCCGCCGGCCAAGGAGGGCTGGAGCAACGCC TTCTATGATAGCTGCGTGAACAGTGTGTCCGACCCCTCCATCTTTGTGATCTTTGAGAAACACCAGGTCTACCCAGAGTATGTCATCCAG >In-frame_HIPK2_ENST00000342645_chr7_139415731_-_PARP12_ENST00000263549_chr7_139728488_-_1788nt CTTCAGCCTGTTTATGAGAGTATGGCCTCACATGTGCAAGTTTTCTCCCCTCACACCCTTCAATCAAGTGCCTTCTGTAGTGTGAAGAAA CTGAAAATAGAGCCGAGTTCCAACTGGGACATGACTGGGTACGGCTCCCACAGCAAAGTGTATAGCCAGAGCAAGAACATCCCCCTGTCG CAGCCAGCCACCACAACCGTCAGCACCTCCTTGCCGGTCCCAAACCCAAGCCTACCTTACGAGCAGACCATCGTCTTCCCAGGAAGCACC GGGCACATCGTGGTCACCTCAGCAAGCAGCACTTCTGTCACCGGGCAAGTCCTCGGCGGACCACACAACCTAATGCGTCGAAGCACTGTG AGCCTCCTTGATACCTACCAAAAATGTGGACTCAAGCGTAAGAGCGAGGAGATCGAGAACACAAGCAGCGTGCAGATCATCGAGGAGCAT CCACCCATGATTCAGAATAATGCAAGCGGGGCCACTGTCGCCACTGCCACCACGTCTACTGCCACCTCCAAAAACAGCGGCTCCAACAGC GAGGGCGACTATCAGCTGGTGCAGCATGAGGTGCTGTGCTCCATGACCAACACCTACGAGGTCTTAGAGTTCTTGGGCCGAGGGACGTTT GGGCAAGTGGTCAAGTGCTGGAAACGGGGCACCAATGAGATCGTAGCCATCAAGATCCTGAAGAACCACCCATCCTATGCCCGACAAGGT CAGATTGAAGTGAGCATCCTGGCCCGGTTGAGCACGGAGAGTGCCGATGACTATAACTTCGTCCGGGCCTACGAATGCTTCCAGCACAAG AACCACACGTGCTTGGTCTTCGAGATGTTGGAGCAGAACCTCTATGACTTTCTGAAGCAAAACAAGTTTAGCCCCTTGCCCCTCAAATAC ATTCGCCCAGTTCTCCAGCAGGTAGCCACAGCCCTGATGAAACTCAAAAGCCTAGGTCTTATCCACGCTGACCTCAAACCAGAAAACATC ATGCTGGTGGATCCATCTAGACAACCATACAGAGTCAAGGTCATCGACTTTGGTTCAGCCAGCCACGTCTCCAAGGCTGTGTGCTCCACC TACTTGCAGTCCAGATATTACAGCAATACCAAGTTTCCAGGCCCGAAGAGCATCCCAGACTATTGGGACTCCTCTGCCCTGCCAGACCCA GGCTTTCAGAAGATCACCCTTAGTTCTTCCTCGGAAGAGTATCAGAAGGTCTGGAACCTCTTTAACCGCACGCTGCCTTTCTACTTTGTT CAGAAGATTGAGCGAGTACAGAACCTGGCCCTCTGGGAAGTCTACCAGTGGCAAAAAGGACAGATGCAGAAGCAGAACGGAGGGAAGGCC GTGGACGAGCGGCAGCTGTTCCACGGCACCAGCGCCATTTTTGTGGACGCCATCTGCCAGCAGAACTTTGACTGGCGGGTCTGTGGTGTT CATGGCACTTCCTACGGCAAGGGGAGCTACTTTGCCCGAGATGCTGCATATTCCCACCACTACAGCAAATCCGACACGCAGACCCACACG ATGTTCCTGGCCCGGGTGCTGGTGGGCGAGTTCGTCAGGGGCAATGCCTCCTTTGTCCGTCCGCCGGCCAAGGAGGGCTGGAGCAACGCC TTCTATGATAGCTGCGTGAACAGTGTGTCCGACCCCTCCATCTTTGTGATCTTTGAGAAACACCAGGTCTACCCAGAGTATGTCATCCAG >In-frame_HIPK2_ENST00000406875_chr7_139415731_-_PARP12_ENST00000263549_chr7_139726148_-_1581nt ATGGCCCCCGTGTACGAAGGTATGGCCTCACATGTGCAAGTTTTCTCCCCTCACACCCTTCAATCAAGTGCCTTCTGTAGTGTGAAGAAA CTGAAAATAGAGCCGAGTTCCAACTGGGACATGACTGGGTACGGCTCCCACAGCAAAGTGTATAGCCAGAGCAAGAACATCCCCCTGTCG CAGCCAGCCACCACAACCGTCAGCACCTCCTTGCCGGTCCCAAACCCAAGCCTACCTTACGAGCAGACCATCGTCTTCCCAGGAAGCACC GGGCACATCGTGGTCACCTCAGCAAGCAGCACTTCTGTCACCGGGCAAGTCCTCGGCGGACCACACAACCTAATGCGTCGAAGCACTGTG AGCCTCCTTGATACCTACCAAAAATGTGGACTCAAGCGTAAGAGCGAGGAGATCGAGAACACAAGCAGCGTGCAGATCATCGAGGAGCAT CCACCCATGATTCAGAATAATGCAAGCGGGGCCACTGTCGCCACTGCCACCACGTCTACTGCCACCTCCAAAAACAGCGGCTCCAACAGC GAGGGCGACTATCAGCTGGTGCAGCATGAGGTGCTGTGCTCCATGACCAACACCTACGAGGTCTTAGAGTTCTTGGGCCGAGGGACGTTT GGGCAAGTGGTCAAGTGCTGGAAACGGGGCACCAATGAGATCGTAGCCATCAAGATCCTGAAGAACCACCCATCCTATGCCCGACAAGGT CAGATTGAAGTGAGCATCCTGGCCCGGTTGAGCACGGAGAGTGCCGATGACTATAACTTCGTCCGGGCCTACGAATGCTTCCAGCACAAG AACCACACGTGCTTGGTCTTCGAGATGTTGGAGCAGAACCTCTATGACTTTCTGAAGCAAAACAAGTTTAGCCCCTTGCCCCTCAAATAC ATTCGCCCAGTTCTCCAGCAGGTAGCCACAGCCCTGATGAAACTCAAAAGCCTAGGTCTTATCCACGCTGACCTCAAACCAGAAAACATC ATGCTGGTGGATCCATCTAGACAACCATACAGAGTCAAGGTCATCGACTTTGGTTCAGCCAGCCACGTCTCCAAGGCTGTGTGCTCCACC TACTTGCAGTCCAGATATTACAGGCAAAAAGGACAGATGCAGAAGCAGAACGGAGGGAAGGCCGTGGACGAGCGGCAGCTGTTCCACGGC ACCAGCGCCATTTTTGTGGACGCCATCTGCCAGCAGAACTTTGACTGGCGGGTCTGTGGTGTTCATGGCACTTCCTACGGCAAGGGGAGC TACTTTGCCCGAGATGCTGCATATTCCCACCACTACAGCAAATCCGACACGCAGACCCACACGATGTTCCTGGCCCGGGTGCTGGTGGGC GAGTTCGTCAGGGGCAATGCCTCCTTTGTCCGTCCGCCGGCCAAGGAGGGCTGGAGCAACGCCTTCTATGATAGCTGCGTGAACAGTGTG TCCGACCCCTCCATCTTTGTGATCTTTGAGAAACACCAGGTCTACCCAGAGTATGTCATCCAGTACACCACCTCCTCCAAGCCCTCGGTC >In-frame_HIPK2_ENST00000428878_chr7_139415731_-_PARP12_ENST00000263549_chr7_139726148_-_1581nt ATGGCCCCCGTGTACGAAGGTATGGCCTCACATGTGCAAGTTTTCTCCCCTCACACCCTTCAATCAAGTGCCTTCTGTAGTGTGAAGAAA CTGAAAATAGAGCCGAGTTCCAACTGGGACATGACTGGGTACGGCTCCCACAGCAAAGTGTATAGCCAGAGCAAGAACATCCCCCTGTCG CAGCCAGCCACCACAACCGTCAGCACCTCCTTGCCGGTCCCAAACCCAAGCCTACCTTACGAGCAGACCATCGTCTTCCCAGGAAGCACC GGGCACATCGTGGTCACCTCAGCAAGCAGCACTTCTGTCACCGGGCAAGTCCTCGGCGGACCACACAACCTAATGCGTCGAAGCACTGTG AGCCTCCTTGATACCTACCAAAAATGTGGACTCAAGCGTAAGAGCGAGGAGATCGAGAACACAAGCAGCGTGCAGATCATCGAGGAGCAT CCACCCATGATTCAGAATAATGCAAGCGGGGCCACTGTCGCCACTGCCACCACGTCTACTGCCACCTCCAAAAACAGCGGCTCCAACAGC GAGGGCGACTATCAGCTGGTGCAGCATGAGGTGCTGTGCTCCATGACCAACACCTACGAGGTCTTAGAGTTCTTGGGCCGAGGGACGTTT GGGCAAGTGGTCAAGTGCTGGAAACGGGGCACCAATGAGATCGTAGCCATCAAGATCCTGAAGAACCACCCATCCTATGCCCGACAAGGT CAGATTGAAGTGAGCATCCTGGCCCGGTTGAGCACGGAGAGTGCCGATGACTATAACTTCGTCCGGGCCTACGAATGCTTCCAGCACAAG AACCACACGTGCTTGGTCTTCGAGATGTTGGAGCAGAACCTCTATGACTTTCTGAAGCAAAACAAGTTTAGCCCCTTGCCCCTCAAATAC ATTCGCCCAGTTCTCCAGCAGGTAGCCACAGCCCTGATGAAACTCAAAAGCCTAGGTCTTATCCACGCTGACCTCAAACCAGAAAACATC ATGCTGGTGGATCCATCTAGACAACCATACAGAGTCAAGGTCATCGACTTTGGTTCAGCCAGCCACGTCTCCAAGGCTGTGTGCTCCACC TACTTGCAGTCCAGATATTACAGGCAAAAAGGACAGATGCAGAAGCAGAACGGAGGGAAGGCCGTGGACGAGCGGCAGCTGTTCCACGGC ACCAGCGCCATTTTTGTGGACGCCATCTGCCAGCAGAACTTTGACTGGCGGGTCTGTGGTGTTCATGGCACTTCCTACGGCAAGGGGAGC TACTTTGCCCGAGATGCTGCATATTCCCACCACTACAGCAAATCCGACACGCAGACCCACACGATGTTCCTGGCCCGGGTGCTGGTGGGC GAGTTCGTCAGGGGCAATGCCTCCTTTGTCCGTCCGCCGGCCAAGGAGGGCTGGAGCAACGCCTTCTATGATAGCTGCGTGAACAGTGTG TCCGACCCCTCCATCTTTGTGATCTTTGAGAAACACCAGGTCTACCCAGAGTATGTCATCCAGTACACCACCTCCTCCAAGCCCTCGGTC >In-frame_HIPK2_ENST00000342645_chr7_139415731_-_PARP12_ENST00000263549_chr7_139726148_-_1581nt CTTCAGCCTGTTTATGAGAGTATGGCCTCACATGTGCAAGTTTTCTCCCCTCACACCCTTCAATCAAGTGCCTTCTGTAGTGTGAAGAAA CTGAAAATAGAGCCGAGTTCCAACTGGGACATGACTGGGTACGGCTCCCACAGCAAAGTGTATAGCCAGAGCAAGAACATCCCCCTGTCG CAGCCAGCCACCACAACCGTCAGCACCTCCTTGCCGGTCCCAAACCCAAGCCTACCTTACGAGCAGACCATCGTCTTCCCAGGAAGCACC GGGCACATCGTGGTCACCTCAGCAAGCAGCACTTCTGTCACCGGGCAAGTCCTCGGCGGACCACACAACCTAATGCGTCGAAGCACTGTG AGCCTCCTTGATACCTACCAAAAATGTGGACTCAAGCGTAAGAGCGAGGAGATCGAGAACACAAGCAGCGTGCAGATCATCGAGGAGCAT CCACCCATGATTCAGAATAATGCAAGCGGGGCCACTGTCGCCACTGCCACCACGTCTACTGCCACCTCCAAAAACAGCGGCTCCAACAGC GAGGGCGACTATCAGCTGGTGCAGCATGAGGTGCTGTGCTCCATGACCAACACCTACGAGGTCTTAGAGTTCTTGGGCCGAGGGACGTTT GGGCAAGTGGTCAAGTGCTGGAAACGGGGCACCAATGAGATCGTAGCCATCAAGATCCTGAAGAACCACCCATCCTATGCCCGACAAGGT CAGATTGAAGTGAGCATCCTGGCCCGGTTGAGCACGGAGAGTGCCGATGACTATAACTTCGTCCGGGCCTACGAATGCTTCCAGCACAAG AACCACACGTGCTTGGTCTTCGAGATGTTGGAGCAGAACCTCTATGACTTTCTGAAGCAAAACAAGTTTAGCCCCTTGCCCCTCAAATAC ATTCGCCCAGTTCTCCAGCAGGTAGCCACAGCCCTGATGAAACTCAAAAGCCTAGGTCTTATCCACGCTGACCTCAAACCAGAAAACATC ATGCTGGTGGATCCATCTAGACAACCATACAGAGTCAAGGTCATCGACTTTGGTTCAGCCAGCCACGTCTCCAAGGCTGTGTGCTCCACC TACTTGCAGTCCAGATATTACAGGCAAAAAGGACAGATGCAGAAGCAGAACGGAGGGAAGGCCGTGGACGAGCGGCAGCTGTTCCACGGC ACCAGCGCCATTTTTGTGGACGCCATCTGCCAGCAGAACTTTGACTGGCGGGTCTGTGGTGTTCATGGCACTTCCTACGGCAAGGGGAGC TACTTTGCCCGAGATGCTGCATATTCCCACCACTACAGCAAATCCGACACGCAGACCCACACGATGTTCCTGGCCCGGGTGCTGGTGGGC GAGTTCGTCAGGGGCAATGCCTCCTTTGTCCGTCCGCCGGCCAAGGAGGGCTGGAGCAACGCCTTCTATGATAGCTGCGTGAACAGTGTG TCCGACCCCTCCATCTTTGTGATCTTTGAGAAACACCAGGTCTACCCAGAGTATGTCATCCAGTACACCACCTCCTCCAAGCCCTCGGTC |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_HIPK2_ENST00000406875_chr7_139415731_-_PARP12_ENST00000263549_chr7_139728488_-_2699nt CTCAAGATGGCAGATTCCGACTGAGGCTGGGGGGGCCGAGCTCGCGCGCCGCTTTCCCGTCCCCGTTGCCATGAACCGCGGACACCCCGG CCCCGATGGCCCCCGTGTACGAAGGTATGGCCTCACATGTGCAAGTTTTCTCCCCTCACACCCTTCAATCAAGTGCCTTCTGTAGTGTGA AGAAACTGAAAATAGAGCCGAGTTCCAACTGGGACATGACTGGGTACGGCTCCCACAGCAAAGTGTATAGCCAGAGCAAGAACATCCCCC TGTCGCAGCCAGCCACCACAACCGTCAGCACCTCCTTGCCGGTCCCAAACCCAAGCCTACCTTACGAGCAGACCATCGTCTTCCCAGGAA GCACCGGGCACATCGTGGTCACCTCAGCAAGCAGCACTTCTGTCACCGGGCAAGTCCTCGGCGGACCACACAACCTAATGCGTCGAAGCA CTGTGAGCCTCCTTGATACCTACCAAAAATGTGGACTCAAGCGTAAGAGCGAGGAGATCGAGAACACAAGCAGCGTGCAGATCATCGAGG AGCATCCACCCATGATTCAGAATAATGCAAGCGGGGCCACTGTCGCCACTGCCACCACGTCTACTGCCACCTCCAAAAACAGCGGCTCCA ACAGCGAGGGCGACTATCAGCTGGTGCAGCATGAGGTGCTGTGCTCCATGACCAACACCTACGAGGTCTTAGAGTTCTTGGGCCGAGGGA CGTTTGGGCAAGTGGTCAAGTGCTGGAAACGGGGCACCAATGAGATCGTAGCCATCAAGATCCTGAAGAACCACCCATCCTATGCCCGAC AAGGTCAGATTGAAGTGAGCATCCTGGCCCGGTTGAGCACGGAGAGTGCCGATGACTATAACTTCGTCCGGGCCTACGAATGCTTCCAGC ACAAGAACCACACGTGCTTGGTCTTCGAGATGTTGGAGCAGAACCTCTATGACTTTCTGAAGCAAAACAAGTTTAGCCCCTTGCCCCTCA AATACATTCGCCCAGTTCTCCAGCAGGTAGCCACAGCCCTGATGAAACTCAAAAGCCTAGGTCTTATCCACGCTGACCTCAAACCAGAAA ACATCATGCTGGTGGATCCATCTAGACAACCATACAGAGTCAAGGTCATCGACTTTGGTTCAGCCAGCCACGTCTCCAAGGCTGTGTGCT CCACCTACTTGCAGTCCAGATATTACAGCAATACCAAGTTTCCAGGCCCGAAGAGCATCCCAGACTATTGGGACTCCTCTGCCCTGCCAG ACCCAGGCTTTCAGAAGATCACCCTTAGTTCTTCCTCGGAAGAGTATCAGAAGGTCTGGAACCTCTTTAACCGCACGCTGCCTTTCTACT TTGTTCAGAAGATTGAGCGAGTACAGAACCTGGCCCTCTGGGAAGTCTACCAGTGGCAAAAAGGACAGATGCAGAAGCAGAACGGAGGGA AGGCCGTGGACGAGCGGCAGCTGTTCCACGGCACCAGCGCCATTTTTGTGGACGCCATCTGCCAGCAGAACTTTGACTGGCGGGTCTGTG GTGTTCATGGCACTTCCTACGGCAAGGGGAGCTACTTTGCCCGAGATGCTGCATATTCCCACCACTACAGCAAATCCGACACGCAGACCC ACACGATGTTCCTGGCCCGGGTGCTGGTGGGCGAGTTCGTCAGGGGCAATGCCTCCTTTGTCCGTCCGCCGGCCAAGGAGGGCTGGAGCA ACGCCTTCTATGATAGCTGCGTGAACAGTGTGTCCGACCCCTCCATCTTTGTGATCTTTGAGAAACACCAGGTCTACCCAGAGTATGTCA TCCAGTACACCACCTCCTCCAAGCCCTCGGTCACACCCTCCATCCTGCTGGCCTTGGGCTCCCTGTTCAGCAGCCGACAGTGAGCGCACA GGAGTGTTCCAGGCCTTTCACCTGCTCTGCCTTGAAATGGCTATTTGGGCCTTTCCTTTTCTTTTTAAACAGAAACTTTTAATGAACTGT TCTCTTAACATTGACCTCTCAATGAAGTTATGTTCTTAATCTCTTGCTAATAATGATTTTTACTTTTAAGTCACTTTTGGGTTCACTAGT GGATTAACCAGAAGTGATTGTAGTTGAGTCCAGTTTTGCTTTTTAATAATGTGTTGAAGTTTTAGTTTTTACTCTTTGTTGACTTTGCTG CTTATTGGCACCAGGGACAGAGTTTCTAGATACAATTTTATGGATTGGTTTTAATTTTTATGAGTTTGTCTCTGCAGTGATTCGGTTTCT CAGAGTCTCATGGCATCATAGTTTTTCCAGAATGACACAGTAGCCACCGGTGGATGACAGCCCACGGGCGGCACAGTCACTTCTGCCTGT TGCTCTGACACCAACCCAGGCAGCTCTGCTGTGGCTTCTCCTGGGCTCTGGCATTAGTTGGTCTGTGTCACATTGTCAGAACAGGTGGCT GCTGTGTGGTGCCATCGAGTCCCTGCTGGTTCCCCTTGTCCTGGGAGGGTCACCCATTGCCCAAGGAAGTGCATCCACCTGGCAGGTGAC CTGGAGGAGTAGCTTCCCCGAGGACCCCCAGGCTTGGCCTGTGATTGCGCAAACCCACATTTCCTAAGCACACTGGACACCCTTCGAGTG >In-frame_HIPK2_ENST00000428878_chr7_139415731_-_PARP12_ENST00000263549_chr7_139728488_-_2759nt CACGGGAGGCGGTGATGCGGGCGCGGGCGGCCTCGGCTGCGCCGAGAGCGGAGACACAGGCTCAAGATGGCAGATTCCGACTGAGGCTGG GGGGGCCGAGCTCGCGCGCCGCTTTCCCGTCCCCGTTGCCATGAACCGCGGACACCCCGGCCCCGATGGCCCCCGTGTACGAAGGTATGG CCTCACATGTGCAAGTTTTCTCCCCTCACACCCTTCAATCAAGTGCCTTCTGTAGTGTGAAGAAACTGAAAATAGAGCCGAGTTCCAACT GGGACATGACTGGGTACGGCTCCCACAGCAAAGTGTATAGCCAGAGCAAGAACATCCCCCTGTCGCAGCCAGCCACCACAACCGTCAGCA CCTCCTTGCCGGTCCCAAACCCAAGCCTACCTTACGAGCAGACCATCGTCTTCCCAGGAAGCACCGGGCACATCGTGGTCACCTCAGCAA GCAGCACTTCTGTCACCGGGCAAGTCCTCGGCGGACCACACAACCTAATGCGTCGAAGCACTGTGAGCCTCCTTGATACCTACCAAAAAT GTGGACTCAAGCGTAAGAGCGAGGAGATCGAGAACACAAGCAGCGTGCAGATCATCGAGGAGCATCCACCCATGATTCAGAATAATGCAA GCGGGGCCACTGTCGCCACTGCCACCACGTCTACTGCCACCTCCAAAAACAGCGGCTCCAACAGCGAGGGCGACTATCAGCTGGTGCAGC ATGAGGTGCTGTGCTCCATGACCAACACCTACGAGGTCTTAGAGTTCTTGGGCCGAGGGACGTTTGGGCAAGTGGTCAAGTGCTGGAAAC GGGGCACCAATGAGATCGTAGCCATCAAGATCCTGAAGAACCACCCATCCTATGCCCGACAAGGTCAGATTGAAGTGAGCATCCTGGCCC GGTTGAGCACGGAGAGTGCCGATGACTATAACTTCGTCCGGGCCTACGAATGCTTCCAGCACAAGAACCACACGTGCTTGGTCTTCGAGA TGTTGGAGCAGAACCTCTATGACTTTCTGAAGCAAAACAAGTTTAGCCCCTTGCCCCTCAAATACATTCGCCCAGTTCTCCAGCAGGTAG CCACAGCCCTGATGAAACTCAAAAGCCTAGGTCTTATCCACGCTGACCTCAAACCAGAAAACATCATGCTGGTGGATCCATCTAGACAAC CATACAGAGTCAAGGTCATCGACTTTGGTTCAGCCAGCCACGTCTCCAAGGCTGTGTGCTCCACCTACTTGCAGTCCAGATATTACAGCA ATACCAAGTTTCCAGGCCCGAAGAGCATCCCAGACTATTGGGACTCCTCTGCCCTGCCAGACCCAGGCTTTCAGAAGATCACCCTTAGTT CTTCCTCGGAAGAGTATCAGAAGGTCTGGAACCTCTTTAACCGCACGCTGCCTTTCTACTTTGTTCAGAAGATTGAGCGAGTACAGAACC TGGCCCTCTGGGAAGTCTACCAGTGGCAAAAAGGACAGATGCAGAAGCAGAACGGAGGGAAGGCCGTGGACGAGCGGCAGCTGTTCCACG GCACCAGCGCCATTTTTGTGGACGCCATCTGCCAGCAGAACTTTGACTGGCGGGTCTGTGGTGTTCATGGCACTTCCTACGGCAAGGGGA GCTACTTTGCCCGAGATGCTGCATATTCCCACCACTACAGCAAATCCGACACGCAGACCCACACGATGTTCCTGGCCCGGGTGCTGGTGG GCGAGTTCGTCAGGGGCAATGCCTCCTTTGTCCGTCCGCCGGCCAAGGAGGGCTGGAGCAACGCCTTCTATGATAGCTGCGTGAACAGTG TGTCCGACCCCTCCATCTTTGTGATCTTTGAGAAACACCAGGTCTACCCAGAGTATGTCATCCAGTACACCACCTCCTCCAAGCCCTCGG TCACACCCTCCATCCTGCTGGCCTTGGGCTCCCTGTTCAGCAGCCGACAGTGAGCGCACAGGAGTGTTCCAGGCCTTTCACCTGCTCTGC CTTGAAATGGCTATTTGGGCCTTTCCTTTTCTTTTTAAACAGAAACTTTTAATGAACTGTTCTCTTAACATTGACCTCTCAATGAAGTTA TGTTCTTAATCTCTTGCTAATAATGATTTTTACTTTTAAGTCACTTTTGGGTTCACTAGTGGATTAACCAGAAGTGATTGTAGTTGAGTC CAGTTTTGCTTTTTAATAATGTGTTGAAGTTTTAGTTTTTACTCTTTGTTGACTTTGCTGCTTATTGGCACCAGGGACAGAGTTTCTAGA TACAATTTTATGGATTGGTTTTAATTTTTATGAGTTTGTCTCTGCAGTGATTCGGTTTCTCAGAGTCTCATGGCATCATAGTTTTTCCAG AATGACACAGTAGCCACCGGTGGATGACAGCCCACGGGCGGCACAGTCACTTCTGCCTGTTGCTCTGACACCAACCCAGGCAGCTCTGCT GTGGCTTCTCCTGGGCTCTGGCATTAGTTGGTCTGTGTCACATTGTCAGAACAGGTGGCTGCTGTGTGGTGCCATCGAGTCCCTGCTGGT TCCCCTTGTCCTGGGAGGGTCACCCATTGCCCAAGGAAGTGCATCCACCTGGCAGGTGACCTGGAGGAGTAGCTTCCCCGAGGACCCCCA GGCTTGGCCTGTGATTGCGCAAACCCACATTTCCTAAGCACACTGGACACCCTTCGAGTGTGGGTTTTAACATCCCTGTGAGATTGAATA >In-frame_HIPK2_ENST00000342645_chr7_139415731_-_PARP12_ENST00000263549_chr7_139728488_-_2604nt CTTCAGCCTGTTTATGAGAGTATGGCCTCACATGTGCAAGTTTTCTCCCCTCACACCCTTCAATCAAGTGCCTTCTGTAGTGTGAAGAAA CTGAAAATAGAGCCGAGTTCCAACTGGGACATGACTGGGTACGGCTCCCACAGCAAAGTGTATAGCCAGAGCAAGAACATCCCCCTGTCG CAGCCAGCCACCACAACCGTCAGCACCTCCTTGCCGGTCCCAAACCCAAGCCTACCTTACGAGCAGACCATCGTCTTCCCAGGAAGCACC GGGCACATCGTGGTCACCTCAGCAAGCAGCACTTCTGTCACCGGGCAAGTCCTCGGCGGACCACACAACCTAATGCGTCGAAGCACTGTG AGCCTCCTTGATACCTACCAAAAATGTGGACTCAAGCGTAAGAGCGAGGAGATCGAGAACACAAGCAGCGTGCAGATCATCGAGGAGCAT CCACCCATGATTCAGAATAATGCAAGCGGGGCCACTGTCGCCACTGCCACCACGTCTACTGCCACCTCCAAAAACAGCGGCTCCAACAGC GAGGGCGACTATCAGCTGGTGCAGCATGAGGTGCTGTGCTCCATGACCAACACCTACGAGGTCTTAGAGTTCTTGGGCCGAGGGACGTTT GGGCAAGTGGTCAAGTGCTGGAAACGGGGCACCAATGAGATCGTAGCCATCAAGATCCTGAAGAACCACCCATCCTATGCCCGACAAGGT CAGATTGAAGTGAGCATCCTGGCCCGGTTGAGCACGGAGAGTGCCGATGACTATAACTTCGTCCGGGCCTACGAATGCTTCCAGCACAAG AACCACACGTGCTTGGTCTTCGAGATGTTGGAGCAGAACCTCTATGACTTTCTGAAGCAAAACAAGTTTAGCCCCTTGCCCCTCAAATAC ATTCGCCCAGTTCTCCAGCAGGTAGCCACAGCCCTGATGAAACTCAAAAGCCTAGGTCTTATCCACGCTGACCTCAAACCAGAAAACATC ATGCTGGTGGATCCATCTAGACAACCATACAGAGTCAAGGTCATCGACTTTGGTTCAGCCAGCCACGTCTCCAAGGCTGTGTGCTCCACC TACTTGCAGTCCAGATATTACAGCAATACCAAGTTTCCAGGCCCGAAGAGCATCCCAGACTATTGGGACTCCTCTGCCCTGCCAGACCCA GGCTTTCAGAAGATCACCCTTAGTTCTTCCTCGGAAGAGTATCAGAAGGTCTGGAACCTCTTTAACCGCACGCTGCCTTTCTACTTTGTT CAGAAGATTGAGCGAGTACAGAACCTGGCCCTCTGGGAAGTCTACCAGTGGCAAAAAGGACAGATGCAGAAGCAGAACGGAGGGAAGGCC GTGGACGAGCGGCAGCTGTTCCACGGCACCAGCGCCATTTTTGTGGACGCCATCTGCCAGCAGAACTTTGACTGGCGGGTCTGTGGTGTT CATGGCACTTCCTACGGCAAGGGGAGCTACTTTGCCCGAGATGCTGCATATTCCCACCACTACAGCAAATCCGACACGCAGACCCACACG ATGTTCCTGGCCCGGGTGCTGGTGGGCGAGTTCGTCAGGGGCAATGCCTCCTTTGTCCGTCCGCCGGCCAAGGAGGGCTGGAGCAACGCC TTCTATGATAGCTGCGTGAACAGTGTGTCCGACCCCTCCATCTTTGTGATCTTTGAGAAACACCAGGTCTACCCAGAGTATGTCATCCAG TACACCACCTCCTCCAAGCCCTCGGTCACACCCTCCATCCTGCTGGCCTTGGGCTCCCTGTTCAGCAGCCGACAGTGAGCGCACAGGAGT GTTCCAGGCCTTTCACCTGCTCTGCCTTGAAATGGCTATTTGGGCCTTTCCTTTTCTTTTTAAACAGAAACTTTTAATGAACTGTTCTCT TAACATTGACCTCTCAATGAAGTTATGTTCTTAATCTCTTGCTAATAATGATTTTTACTTTTAAGTCACTTTTGGGTTCACTAGTGGATT AACCAGAAGTGATTGTAGTTGAGTCCAGTTTTGCTTTTTAATAATGTGTTGAAGTTTTAGTTTTTACTCTTTGTTGACTTTGCTGCTTAT TGGCACCAGGGACAGAGTTTCTAGATACAATTTTATGGATTGGTTTTAATTTTTATGAGTTTGTCTCTGCAGTGATTCGGTTTCTCAGAG TCTCATGGCATCATAGTTTTTCCAGAATGACACAGTAGCCACCGGTGGATGACAGCCCACGGGCGGCACAGTCACTTCTGCCTGTTGCTC TGACACCAACCCAGGCAGCTCTGCTGTGGCTTCTCCTGGGCTCTGGCATTAGTTGGTCTGTGTCACATTGTCAGAACAGGTGGCTGCTGT GTGGTGCCATCGAGTCCCTGCTGGTTCCCCTTGTCCTGGGAGGGTCACCCATTGCCCAAGGAAGTGCATCCACCTGGCAGGTGACCTGGA GGAGTAGCTTCCCCGAGGACCCCCAGGCTTGGCCTGTGATTGCGCAAACCCACATTTCCTAAGCACACTGGACACCCTTCGAGTGTGGGT >In-frame_HIPK2_ENST00000406875_chr7_139415731_-_PARP12_ENST00000263549_chr7_139726148_-_2492nt CTCAAGATGGCAGATTCCGACTGAGGCTGGGGGGGCCGAGCTCGCGCGCCGCTTTCCCGTCCCCGTTGCCATGAACCGCGGACACCCCGG CCCCGATGGCCCCCGTGTACGAAGGTATGGCCTCACATGTGCAAGTTTTCTCCCCTCACACCCTTCAATCAAGTGCCTTCTGTAGTGTGA AGAAACTGAAAATAGAGCCGAGTTCCAACTGGGACATGACTGGGTACGGCTCCCACAGCAAAGTGTATAGCCAGAGCAAGAACATCCCCC TGTCGCAGCCAGCCACCACAACCGTCAGCACCTCCTTGCCGGTCCCAAACCCAAGCCTACCTTACGAGCAGACCATCGTCTTCCCAGGAA GCACCGGGCACATCGTGGTCACCTCAGCAAGCAGCACTTCTGTCACCGGGCAAGTCCTCGGCGGACCACACAACCTAATGCGTCGAAGCA CTGTGAGCCTCCTTGATACCTACCAAAAATGTGGACTCAAGCGTAAGAGCGAGGAGATCGAGAACACAAGCAGCGTGCAGATCATCGAGG AGCATCCACCCATGATTCAGAATAATGCAAGCGGGGCCACTGTCGCCACTGCCACCACGTCTACTGCCACCTCCAAAAACAGCGGCTCCA ACAGCGAGGGCGACTATCAGCTGGTGCAGCATGAGGTGCTGTGCTCCATGACCAACACCTACGAGGTCTTAGAGTTCTTGGGCCGAGGGA CGTTTGGGCAAGTGGTCAAGTGCTGGAAACGGGGCACCAATGAGATCGTAGCCATCAAGATCCTGAAGAACCACCCATCCTATGCCCGAC AAGGTCAGATTGAAGTGAGCATCCTGGCCCGGTTGAGCACGGAGAGTGCCGATGACTATAACTTCGTCCGGGCCTACGAATGCTTCCAGC ACAAGAACCACACGTGCTTGGTCTTCGAGATGTTGGAGCAGAACCTCTATGACTTTCTGAAGCAAAACAAGTTTAGCCCCTTGCCCCTCA AATACATTCGCCCAGTTCTCCAGCAGGTAGCCACAGCCCTGATGAAACTCAAAAGCCTAGGTCTTATCCACGCTGACCTCAAACCAGAAA ACATCATGCTGGTGGATCCATCTAGACAACCATACAGAGTCAAGGTCATCGACTTTGGTTCAGCCAGCCACGTCTCCAAGGCTGTGTGCT CCACCTACTTGCAGTCCAGATATTACAGGCAAAAAGGACAGATGCAGAAGCAGAACGGAGGGAAGGCCGTGGACGAGCGGCAGCTGTTCC ACGGCACCAGCGCCATTTTTGTGGACGCCATCTGCCAGCAGAACTTTGACTGGCGGGTCTGTGGTGTTCATGGCACTTCCTACGGCAAGG GGAGCTACTTTGCCCGAGATGCTGCATATTCCCACCACTACAGCAAATCCGACACGCAGACCCACACGATGTTCCTGGCCCGGGTGCTGG TGGGCGAGTTCGTCAGGGGCAATGCCTCCTTTGTCCGTCCGCCGGCCAAGGAGGGCTGGAGCAACGCCTTCTATGATAGCTGCGTGAACA GTGTGTCCGACCCCTCCATCTTTGTGATCTTTGAGAAACACCAGGTCTACCCAGAGTATGTCATCCAGTACACCACCTCCTCCAAGCCCT CGGTCACACCCTCCATCCTGCTGGCCTTGGGCTCCCTGTTCAGCAGCCGACAGTGAGCGCACAGGAGTGTTCCAGGCCTTTCACCTGCTC TGCCTTGAAATGGCTATTTGGGCCTTTCCTTTTCTTTTTAAACAGAAACTTTTAATGAACTGTTCTCTTAACATTGACCTCTCAATGAAG TTATGTTCTTAATCTCTTGCTAATAATGATTTTTACTTTTAAGTCACTTTTGGGTTCACTAGTGGATTAACCAGAAGTGATTGTAGTTGA GTCCAGTTTTGCTTTTTAATAATGTGTTGAAGTTTTAGTTTTTACTCTTTGTTGACTTTGCTGCTTATTGGCACCAGGGACAGAGTTTCT AGATACAATTTTATGGATTGGTTTTAATTTTTATGAGTTTGTCTCTGCAGTGATTCGGTTTCTCAGAGTCTCATGGCATCATAGTTTTTC CAGAATGACACAGTAGCCACCGGTGGATGACAGCCCACGGGCGGCACAGTCACTTCTGCCTGTTGCTCTGACACCAACCCAGGCAGCTCT GCTGTGGCTTCTCCTGGGCTCTGGCATTAGTTGGTCTGTGTCACATTGTCAGAACAGGTGGCTGCTGTGTGGTGCCATCGAGTCCCTGCT GGTTCCCCTTGTCCTGGGAGGGTCACCCATTGCCCAAGGAAGTGCATCCACCTGGCAGGTGACCTGGAGGAGTAGCTTCCCCGAGGACCC CCAGGCTTGGCCTGTGATTGCGCAAACCCACATTTCCTAAGCACACTGGACACCCTTCGAGTGTGGGTTTTAACATCCCTGTGAGATTGA >In-frame_HIPK2_ENST00000428878_chr7_139415731_-_PARP12_ENST00000263549_chr7_139726148_-_2552nt CACGGGAGGCGGTGATGCGGGCGCGGGCGGCCTCGGCTGCGCCGAGAGCGGAGACACAGGCTCAAGATGGCAGATTCCGACTGAGGCTGG GGGGGCCGAGCTCGCGCGCCGCTTTCCCGTCCCCGTTGCCATGAACCGCGGACACCCCGGCCCCGATGGCCCCCGTGTACGAAGGTATGG CCTCACATGTGCAAGTTTTCTCCCCTCACACCCTTCAATCAAGTGCCTTCTGTAGTGTGAAGAAACTGAAAATAGAGCCGAGTTCCAACT GGGACATGACTGGGTACGGCTCCCACAGCAAAGTGTATAGCCAGAGCAAGAACATCCCCCTGTCGCAGCCAGCCACCACAACCGTCAGCA CCTCCTTGCCGGTCCCAAACCCAAGCCTACCTTACGAGCAGACCATCGTCTTCCCAGGAAGCACCGGGCACATCGTGGTCACCTCAGCAA GCAGCACTTCTGTCACCGGGCAAGTCCTCGGCGGACCACACAACCTAATGCGTCGAAGCACTGTGAGCCTCCTTGATACCTACCAAAAAT GTGGACTCAAGCGTAAGAGCGAGGAGATCGAGAACACAAGCAGCGTGCAGATCATCGAGGAGCATCCACCCATGATTCAGAATAATGCAA GCGGGGCCACTGTCGCCACTGCCACCACGTCTACTGCCACCTCCAAAAACAGCGGCTCCAACAGCGAGGGCGACTATCAGCTGGTGCAGC ATGAGGTGCTGTGCTCCATGACCAACACCTACGAGGTCTTAGAGTTCTTGGGCCGAGGGACGTTTGGGCAAGTGGTCAAGTGCTGGAAAC GGGGCACCAATGAGATCGTAGCCATCAAGATCCTGAAGAACCACCCATCCTATGCCCGACAAGGTCAGATTGAAGTGAGCATCCTGGCCC GGTTGAGCACGGAGAGTGCCGATGACTATAACTTCGTCCGGGCCTACGAATGCTTCCAGCACAAGAACCACACGTGCTTGGTCTTCGAGA TGTTGGAGCAGAACCTCTATGACTTTCTGAAGCAAAACAAGTTTAGCCCCTTGCCCCTCAAATACATTCGCCCAGTTCTCCAGCAGGTAG CCACAGCCCTGATGAAACTCAAAAGCCTAGGTCTTATCCACGCTGACCTCAAACCAGAAAACATCATGCTGGTGGATCCATCTAGACAAC CATACAGAGTCAAGGTCATCGACTTTGGTTCAGCCAGCCACGTCTCCAAGGCTGTGTGCTCCACCTACTTGCAGTCCAGATATTACAGGC AAAAAGGACAGATGCAGAAGCAGAACGGAGGGAAGGCCGTGGACGAGCGGCAGCTGTTCCACGGCACCAGCGCCATTTTTGTGGACGCCA TCTGCCAGCAGAACTTTGACTGGCGGGTCTGTGGTGTTCATGGCACTTCCTACGGCAAGGGGAGCTACTTTGCCCGAGATGCTGCATATT CCCACCACTACAGCAAATCCGACACGCAGACCCACACGATGTTCCTGGCCCGGGTGCTGGTGGGCGAGTTCGTCAGGGGCAATGCCTCCT TTGTCCGTCCGCCGGCCAAGGAGGGCTGGAGCAACGCCTTCTATGATAGCTGCGTGAACAGTGTGTCCGACCCCTCCATCTTTGTGATCT TTGAGAAACACCAGGTCTACCCAGAGTATGTCATCCAGTACACCACCTCCTCCAAGCCCTCGGTCACACCCTCCATCCTGCTGGCCTTGG GCTCCCTGTTCAGCAGCCGACAGTGAGCGCACAGGAGTGTTCCAGGCCTTTCACCTGCTCTGCCTTGAAATGGCTATTTGGGCCTTTCCT TTTCTTTTTAAACAGAAACTTTTAATGAACTGTTCTCTTAACATTGACCTCTCAATGAAGTTATGTTCTTAATCTCTTGCTAATAATGAT TTTTACTTTTAAGTCACTTTTGGGTTCACTAGTGGATTAACCAGAAGTGATTGTAGTTGAGTCCAGTTTTGCTTTTTAATAATGTGTTGA AGTTTTAGTTTTTACTCTTTGTTGACTTTGCTGCTTATTGGCACCAGGGACAGAGTTTCTAGATACAATTTTATGGATTGGTTTTAATTT TTATGAGTTTGTCTCTGCAGTGATTCGGTTTCTCAGAGTCTCATGGCATCATAGTTTTTCCAGAATGACACAGTAGCCACCGGTGGATGA CAGCCCACGGGCGGCACAGTCACTTCTGCCTGTTGCTCTGACACCAACCCAGGCAGCTCTGCTGTGGCTTCTCCTGGGCTCTGGCATTAG TTGGTCTGTGTCACATTGTCAGAACAGGTGGCTGCTGTGTGGTGCCATCGAGTCCCTGCTGGTTCCCCTTGTCCTGGGAGGGTCACCCAT TGCCCAAGGAAGTGCATCCACCTGGCAGGTGACCTGGAGGAGTAGCTTCCCCGAGGACCCCCAGGCTTGGCCTGTGATTGCGCAAACCCA CATTTCCTAAGCACACTGGACACCCTTCGAGTGTGGGTTTTAACATCCCTGTGAGATTGAATACTTGTGCCACACATGTCACAAAAGAGT >In-frame_HIPK2_ENST00000342645_chr7_139415731_-_PARP12_ENST00000263549_chr7_139726148_-_2397nt CTTCAGCCTGTTTATGAGAGTATGGCCTCACATGTGCAAGTTTTCTCCCCTCACACCCTTCAATCAAGTGCCTTCTGTAGTGTGAAGAAA CTGAAAATAGAGCCGAGTTCCAACTGGGACATGACTGGGTACGGCTCCCACAGCAAAGTGTATAGCCAGAGCAAGAACATCCCCCTGTCG CAGCCAGCCACCACAACCGTCAGCACCTCCTTGCCGGTCCCAAACCCAAGCCTACCTTACGAGCAGACCATCGTCTTCCCAGGAAGCACC GGGCACATCGTGGTCACCTCAGCAAGCAGCACTTCTGTCACCGGGCAAGTCCTCGGCGGACCACACAACCTAATGCGTCGAAGCACTGTG AGCCTCCTTGATACCTACCAAAAATGTGGACTCAAGCGTAAGAGCGAGGAGATCGAGAACACAAGCAGCGTGCAGATCATCGAGGAGCAT CCACCCATGATTCAGAATAATGCAAGCGGGGCCACTGTCGCCACTGCCACCACGTCTACTGCCACCTCCAAAAACAGCGGCTCCAACAGC GAGGGCGACTATCAGCTGGTGCAGCATGAGGTGCTGTGCTCCATGACCAACACCTACGAGGTCTTAGAGTTCTTGGGCCGAGGGACGTTT GGGCAAGTGGTCAAGTGCTGGAAACGGGGCACCAATGAGATCGTAGCCATCAAGATCCTGAAGAACCACCCATCCTATGCCCGACAAGGT CAGATTGAAGTGAGCATCCTGGCCCGGTTGAGCACGGAGAGTGCCGATGACTATAACTTCGTCCGGGCCTACGAATGCTTCCAGCACAAG AACCACACGTGCTTGGTCTTCGAGATGTTGGAGCAGAACCTCTATGACTTTCTGAAGCAAAACAAGTTTAGCCCCTTGCCCCTCAAATAC ATTCGCCCAGTTCTCCAGCAGGTAGCCACAGCCCTGATGAAACTCAAAAGCCTAGGTCTTATCCACGCTGACCTCAAACCAGAAAACATC ATGCTGGTGGATCCATCTAGACAACCATACAGAGTCAAGGTCATCGACTTTGGTTCAGCCAGCCACGTCTCCAAGGCTGTGTGCTCCACC TACTTGCAGTCCAGATATTACAGGCAAAAAGGACAGATGCAGAAGCAGAACGGAGGGAAGGCCGTGGACGAGCGGCAGCTGTTCCACGGC ACCAGCGCCATTTTTGTGGACGCCATCTGCCAGCAGAACTTTGACTGGCGGGTCTGTGGTGTTCATGGCACTTCCTACGGCAAGGGGAGC TACTTTGCCCGAGATGCTGCATATTCCCACCACTACAGCAAATCCGACACGCAGACCCACACGATGTTCCTGGCCCGGGTGCTGGTGGGC GAGTTCGTCAGGGGCAATGCCTCCTTTGTCCGTCCGCCGGCCAAGGAGGGCTGGAGCAACGCCTTCTATGATAGCTGCGTGAACAGTGTG TCCGACCCCTCCATCTTTGTGATCTTTGAGAAACACCAGGTCTACCCAGAGTATGTCATCCAGTACACCACCTCCTCCAAGCCCTCGGTC ACACCCTCCATCCTGCTGGCCTTGGGCTCCCTGTTCAGCAGCCGACAGTGAGCGCACAGGAGTGTTCCAGGCCTTTCACCTGCTCTGCCT TGAAATGGCTATTTGGGCCTTTCCTTTTCTTTTTAAACAGAAACTTTTAATGAACTGTTCTCTTAACATTGACCTCTCAATGAAGTTATG TTCTTAATCTCTTGCTAATAATGATTTTTACTTTTAAGTCACTTTTGGGTTCACTAGTGGATTAACCAGAAGTGATTGTAGTTGAGTCCA GTTTTGCTTTTTAATAATGTGTTGAAGTTTTAGTTTTTACTCTTTGTTGACTTTGCTGCTTATTGGCACCAGGGACAGAGTTTCTAGATA CAATTTTATGGATTGGTTTTAATTTTTATGAGTTTGTCTCTGCAGTGATTCGGTTTCTCAGAGTCTCATGGCATCATAGTTTTTCCAGAA TGACACAGTAGCCACCGGTGGATGACAGCCCACGGGCGGCACAGTCACTTCTGCCTGTTGCTCTGACACCAACCCAGGCAGCTCTGCTGT GGCTTCTCCTGGGCTCTGGCATTAGTTGGTCTGTGTCACATTGTCAGAACAGGTGGCTGCTGTGTGGTGCCATCGAGTCCCTGCTGGTTC CCCTTGTCCTGGGAGGGTCACCCATTGCCCAAGGAAGTGCATCCACCTGGCAGGTGACCTGGAGGAGTAGCTTCCCCGAGGACCCCCAGG CTTGGCCTGTGATTGCGCAAACCCACATTTCCTAAGCACACTGGACACCCTTCGAGTGTGGGTTTTAACATCCCTGTGAGATTGAATACT |
Top |
FusionGenePPI for HIPK2_PARP12 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| HIPK2 | DAXX, SP100, UBE2I, SUMO1, SKI, SMAD1, SMAD2, SMAD3, TP53INP1, TP53, CREBBP, RANBP9, NKX2-1, TRADD, TP73, TP63, FBXW7, BTRC, CUL1, MYB, RUNX1, EP300, HIPK2, NLK, MAP3K7, MYBL1, MYBL2, WSB1, SIAH1P1, SIAH1, SIAH2, CXCL1, AXIN1, HIST2H2BE, SENP2, SENP1, FBXO3, PML, CBX4, PAX6, CHMP4B, DCAF7, DYRK1A, DYRK1B, MAP3K1, MDM2, ZBTB4, MECP2, MBP, MKNK1, AATF, XAF1, SUMO2, SUMO3, RGMA, ABL1, PARP1, HSPA1A, STUB1, LZTS2, ACTBL2, TRIM25 | PARP12 | BCL6, ELAVL1, MLH1, CBX2, CBX4, RPA3, RPA2, RPA1, RNF2, KRAS, XPO1, BHLHA15, RNF166, GCLM, MKRN2, RNF114, TRIM25 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| Hgene | HIPK2 | chr7:139415731 | chr7:139726148 | ENST00000406875 | - | 2 | 15 | 935_1049 | 367 | 1199 | AXIN1 |
| Hgene | HIPK2 | chr7:139415731 | chr7:139726148 | ENST00000428878 | - | 2 | 15 | 935_1049 | 367 | 1172 | AXIN1 |
| Hgene | HIPK2 | chr7:139415731 | chr7:139728488 | ENST00000406875 | - | 2 | 15 | 935_1049 | 367 | 1199 | AXIN1 |
| Hgene | HIPK2 | chr7:139415731 | chr7:139728488 | ENST00000428878 | - | 2 | 15 | 935_1049 | 367 | 1172 | AXIN1 |
| Hgene | HIPK2 | chr7:139415731 | chr7:139726148 | ENST00000406875 | - | 2 | 15 | 774_876 | 367 | 1199 | CTBP1 |
| Hgene | HIPK2 | chr7:139415731 | chr7:139726148 | ENST00000428878 | - | 2 | 15 | 774_876 | 367 | 1172 | CTBP1 |
| Hgene | HIPK2 | chr7:139415731 | chr7:139728488 | ENST00000406875 | - | 2 | 15 | 774_876 | 367 | 1199 | CTBP1 |
| Hgene | HIPK2 | chr7:139415731 | chr7:139728488 | ENST00000428878 | - | 2 | 15 | 774_876 | 367 | 1172 | CTBP1 |
| Hgene | HIPK2 | chr7:139415731 | chr7:139726148 | ENST00000406875 | - | 2 | 15 | 189_520 | 367 | 1199 | DAXX |
| Hgene | HIPK2 | chr7:139415731 | chr7:139726148 | ENST00000428878 | - | 2 | 15 | 189_520 | 367 | 1172 | DAXX |
| Hgene | HIPK2 | chr7:139415731 | chr7:139728488 | ENST00000406875 | - | 2 | 15 | 189_520 | 367 | 1199 | DAXX |
| Hgene | HIPK2 | chr7:139415731 | chr7:139728488 | ENST00000428878 | - | 2 | 15 | 189_520 | 367 | 1172 | DAXX |
| Hgene | HIPK2 | chr7:139415731 | chr7:139726148 | ENST00000406875 | - | 2 | 15 | 787_897 | 367 | 1199 | HMGA1 |
| Hgene | HIPK2 | chr7:139415731 | chr7:139726148 | ENST00000428878 | - | 2 | 15 | 787_897 | 367 | 1172 | HMGA1 |
| Hgene | HIPK2 | chr7:139415731 | chr7:139728488 | ENST00000406875 | - | 2 | 15 | 787_897 | 367 | 1199 | HMGA1 |
| Hgene | HIPK2 | chr7:139415731 | chr7:139728488 | ENST00000428878 | - | 2 | 15 | 787_897 | 367 | 1172 | HMGA1 |
| Hgene | HIPK2 | chr7:139415731 | chr7:139726148 | ENST00000406875 | - | 2 | 15 | 752_897 | 367 | 1199 | POU4F1 |
| Hgene | HIPK2 | chr7:139415731 | chr7:139726148 | ENST00000428878 | - | 2 | 15 | 752_897 | 367 | 1172 | POU4F1 |
| Hgene | HIPK2 | chr7:139415731 | chr7:139728488 | ENST00000406875 | - | 2 | 15 | 752_897 | 367 | 1199 | POU4F1 |
| Hgene | HIPK2 | chr7:139415731 | chr7:139728488 | ENST00000428878 | - | 2 | 15 | 752_897 | 367 | 1172 | POU4F1 |
| Hgene | HIPK2 | chr7:139415731 | chr7:139726148 | ENST00000406875 | - | 2 | 15 | 539_844 | 367 | 1199 | SKI and SMAD1 |
| Hgene | HIPK2 | chr7:139415731 | chr7:139726148 | ENST00000428878 | - | 2 | 15 | 539_844 | 367 | 1172 | SKI and SMAD1 |
| Hgene | HIPK2 | chr7:139415731 | chr7:139728488 | ENST00000406875 | - | 2 | 15 | 539_844 | 367 | 1199 | SKI and SMAD1 |
| Hgene | HIPK2 | chr7:139415731 | chr7:139728488 | ENST00000428878 | - | 2 | 15 | 539_844 | 367 | 1172 | SKI and SMAD1 |
| Hgene | HIPK2 | chr7:139415731 | chr7:139726148 | ENST00000406875 | - | 2 | 15 | 846_941 | 367 | 1199 | TP53 and TP73 |
| Hgene | HIPK2 | chr7:139415731 | chr7:139726148 | ENST00000428878 | - | 2 | 15 | 846_941 | 367 | 1172 | TP53 and TP73 |
| Hgene | HIPK2 | chr7:139415731 | chr7:139728488 | ENST00000406875 | - | 2 | 15 | 846_941 | 367 | 1199 | TP53 and TP73 |
| Hgene | HIPK2 | chr7:139415731 | chr7:139728488 | ENST00000428878 | - | 2 | 15 | 846_941 | 367 | 1172 | TP53 and TP73 |
| Hgene | HIPK2 | chr7:139415731 | chr7:139726148 | ENST00000406875 | - | 2 | 15 | 873_907 | 367 | 1199 | UBE2I |
| Hgene | HIPK2 | chr7:139415731 | chr7:139726148 | ENST00000428878 | - | 2 | 15 | 873_907 | 367 | 1172 | UBE2I |
| Hgene | HIPK2 | chr7:139415731 | chr7:139728488 | ENST00000406875 | - | 2 | 15 | 873_907 | 367 | 1199 | UBE2I |
| Hgene | HIPK2 | chr7:139415731 | chr7:139728488 | ENST00000428878 | - | 2 | 15 | 873_907 | 367 | 1172 | UBE2I |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
Top |
RelatedDrugs for HIPK2_PARP12 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
Top |
RelatedDiseases for HIPK2_PARP12 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Tgene | PARP12 | C0021400 | Influenza | 1 | CTD_human |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
|