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Fusion gene ID: 16093 |
FusionGeneSummary for HERC1_DAPK2 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: HERC1_DAPK2 | Fusion gene ID: 16093 | Hgene | Tgene | Gene symbol | HERC1 | DAPK2 | Gene ID | 8925 | 23604 |
| Gene name | HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 | death associated protein kinase 2 | |
| Synonyms | MDFPMR|p532|p619 | DRP-1|DRP1 | |
| Cytomap | 15q22.31 | 15q22.31 | |
| Type of gene | protein-coding | protein-coding | |
| Description | probable E3 ubiquitin-protein ligase HERC1HECT domain and RCC1-like domain-containing protein 1HECT-type E3 ubiquitin transferase HERC1guanine nucleotide exchange factor p532hect (homologous to the E6-AP (UBE3A) carboxyl terminus) domain and RCC1 (CHC | death-associated protein kinase 2DAP kinase 2DAP-kinase-related protein 1 beta isoform | |
| Modification date | 20180519 | 20180526 | |
| UniProtAcc | Q15751 | Q9UIK4 | |
| Ensembl transtripts involved in fusion gene | ENST00000443617, | ENST00000261891, ENST00000457488, ENST00000558069, ENST00000558482, | |
| Fusion gene scores | * DoF score | 10 X 11 X 9=990 | 6 X 7 X 7=294 |
| # samples | 14 | 10 | |
| ** MAII score | log2(14/990*10)=-2.82200169802201 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(10/294*10)=-1.55581615506164 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: HERC1 [Title/Abstract] AND DAPK2 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | Tumor suppressor gene involved fusion gene, in-frame but not retained their domain. Tumor suppressor gene involved fusion gene, retained protein feature but frameshift. DDR (DNA damage repair) gene involved fusion gene, in-frame but not retained their domain. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Tgene | DAPK2 | GO:0006468 | protein phosphorylation | 10376525 |
| Tgene | DAPK2 | GO:0035556 | intracellular signal transduction | 10376525 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | ACC | TCGA-OR-A5JC-01A | HERC1 | chr15 | 63956669 | - | DAPK2 | chr15 | 64275953 | - |
| TCGA | RV | BLCA | TCGA-DK-A3X2-01A | HERC1 | chr15 | 64126026 | - | DAPK2 | chr15 | 64231560 | - |
| TCGA | RV | BRCA | TCGA-D8-A1JK-01A | HERC1 | chr15 | 64126026 | - | DAPK2 | chr15 | 64204396 | - |
| TCGA | RV | LIHC | TCGA-NI-A8LF-01A | HERC1 | chr15 | 64126026 | - | DAPK2 | chr15 | 64332466 | - |
| TCGA | RV | STAD | TCGA-VQ-A8E2-01A | HERC1 | chr15 | 63988323 | - | DAPK2 | chr15 | 64263760 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| Frame-shift | ENST00000443617 | ENST00000261891 | HERC1 | chr15 | 63956669 | - | DAPK2 | chr15 | 64275953 | - |
| Frame-shift | ENST00000443617 | ENST00000457488 | HERC1 | chr15 | 63956669 | - | DAPK2 | chr15 | 64275953 | - |
| Frame-shift | ENST00000443617 | ENST00000558069 | HERC1 | chr15 | 63956669 | - | DAPK2 | chr15 | 64275953 | - |
| 5CDS-5UTR | ENST00000443617 | ENST00000558482 | HERC1 | chr15 | 63956669 | - | DAPK2 | chr15 | 64275953 | - |
| 5UTR-3CDS | ENST00000443617 | ENST00000261891 | HERC1 | chr15 | 64126026 | - | DAPK2 | chr15 | 64231560 | - |
| 5UTR-3CDS | ENST00000443617 | ENST00000457488 | HERC1 | chr15 | 64126026 | - | DAPK2 | chr15 | 64231560 | - |
| 5UTR-3CDS | ENST00000443617 | ENST00000558069 | HERC1 | chr15 | 64126026 | - | DAPK2 | chr15 | 64231560 | - |
| 5UTR-5UTR | ENST00000443617 | ENST00000558482 | HERC1 | chr15 | 64126026 | - | DAPK2 | chr15 | 64231560 | - |
| 5UTR-3CDS | ENST00000443617 | ENST00000261891 | HERC1 | chr15 | 64126026 | - | DAPK2 | chr15 | 64204396 | - |
| 5UTR-3CDS | ENST00000443617 | ENST00000457488 | HERC1 | chr15 | 64126026 | - | DAPK2 | chr15 | 64204396 | - |
| 5UTR-intron | ENST00000443617 | ENST00000558069 | HERC1 | chr15 | 64126026 | - | DAPK2 | chr15 | 64204396 | - |
| 5UTR-intron | ENST00000443617 | ENST00000558482 | HERC1 | chr15 | 64126026 | - | DAPK2 | chr15 | 64204396 | - |
| 5UTR-3CDS | ENST00000443617 | ENST00000261891 | HERC1 | chr15 | 64126026 | - | DAPK2 | chr15 | 64332466 | - |
| 5UTR-5UTR | ENST00000443617 | ENST00000457488 | HERC1 | chr15 | 64126026 | - | DAPK2 | chr15 | 64332466 | - |
| 5UTR-5UTR | ENST00000443617 | ENST00000558069 | HERC1 | chr15 | 64126026 | - | DAPK2 | chr15 | 64332466 | - |
| 5UTR-5UTR | ENST00000443617 | ENST00000558482 | HERC1 | chr15 | 64126026 | - | DAPK2 | chr15 | 64332466 | - |
| In-frame | ENST00000443617 | ENST00000261891 | HERC1 | chr15 | 63988323 | - | DAPK2 | chr15 | 64263760 | - |
| In-frame | ENST00000443617 | ENST00000457488 | HERC1 | chr15 | 63988323 | - | DAPK2 | chr15 | 64263760 | - |
| In-frame | ENST00000443617 | ENST00000558069 | HERC1 | chr15 | 63988323 | - | DAPK2 | chr15 | 64263760 | - |
| 5CDS-5UTR | ENST00000443617 | ENST00000558482 | HERC1 | chr15 | 63988323 | - | DAPK2 | chr15 | 64263760 | - |
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FusionProtFeatures for HERC1_DAPK2 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| HERC1 | DAPK2 |
| Involved in membrane trafficking via some guaninenucleotide exchange factor (GEF) activity and its ability to bindclathrin. Acts as a GEF for Arf and Rab, by exchanging bound GDPfor free GTP. Binds phosphatidylinositol 4,5-bisphosphate, whichis required for GEF activity. May also act as a E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directlytransfers the ubiquitin to targeted substrates.{ECO:0000269|PubMed:15642342, ECO:0000269|PubMed:8861955,ECO:0000269|PubMed:9233772}. | Calcium/calmodulin-dependent serine/threonine kinaseinvolved in multiple cellular signaling pathways that trigger cellsurvival, apoptosis, and autophagy. Regulates both type Iapoptotic and type II autophagic cell death signals, depending onthe cellular setting. The former is caspase-dependent, while thelatter is caspase-independent and is characterized by theaccumulation of autophagic vesicles. Acts as a mediator of anoikisand a suppressor of beta-catenin-dependent anchorage-independentgrowth of malignant epithelial cells. May play a role ingranulocytic maturation (PubMed:17347302). Regulates granulocyticmotility by controlling cell spreading and polarization(PubMed:24163421). {ECO:0000269|PubMed:17347302,ECO:0000269|PubMed:24163421, ECO:0000269|PubMed:26047703}. Isoform 2 is not regulated by calmodulin. It canphosphorylate MYL9. It can induce membrane blebbing and autophagiccell death. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | HERC1 | chr15:63988323 | chr15:64263760 | ENST00000443617 | - | 27 | 78 | 1349_1378 | 1707 | 4862 | Compositional bias | Note=Glu-rich |
| Hgene | HERC1 | chr15:63988323 | chr15:64263760 | ENST00000443617 | - | 27 | 78 | 371_420 | 1707 | 4862 | Repeat | Note=RCC1 1 |
| Hgene | HERC1 | chr15:63988323 | chr15:64263760 | ENST00000443617 | - | 27 | 78 | 421_475 | 1707 | 4862 | Repeat | Note=RCC1 2 |
| Hgene | HERC1 | chr15:63988323 | chr15:64263760 | ENST00000443617 | - | 27 | 78 | 476_528 | 1707 | 4862 | Repeat | Note=RCC1 3 |
| Hgene | HERC1 | chr15:63988323 | chr15:64263760 | ENST00000443617 | - | 27 | 78 | 529_578 | 1707 | 4862 | Repeat | Note=RCC1 4 |
| Hgene | HERC1 | chr15:63988323 | chr15:64263760 | ENST00000443617 | - | 27 | 78 | 580_631 | 1707 | 4862 | Repeat | Note=RCC1 5 |
| Hgene | HERC1 | chr15:63988323 | chr15:64263760 | ENST00000443617 | - | 27 | 78 | 633_682 | 1707 | 4862 | Repeat | Note=RCC1 6 |
| Hgene | HERC1 | chr15:63988323 | chr15:64263760 | ENST00000443617 | - | 27 | 78 | 683_735 | 1707 | 4862 | Repeat | Note=RCC1 7 |
| Tgene | >DAPK2 | chr15:63988323 | chr15:64263760 | ENST00000261891 | - | 1 | 11 | 277_344 | 104 | 371 | Region | Note=Calmodulin-binding |
| Tgene | >DAPK2 | chr15:63988323 | chr15:64263760 | ENST00000261891 | - | 1 | 11 | 292_301 | 104 | 371 | Region | Autoinhibitory domain |
| Tgene | >DAPK2 | chr15:63988323 | chr15:64263760 | ENST00000457488 | - | 2 | 12 | 277_344 | 104 | 371 | Region | Note=Calmodulin-binding |
| Tgene | >DAPK2 | chr15:63988323 | chr15:64263760 | ENST00000457488 | - | 2 | 12 | 292_301 | 104 | 371 | Region | Autoinhibitory domain |
| Tgene | >DAPK2 | chr15:63988323 | chr15:64263760 | ENST00000558069 | - | 2 | 10 | 277_344 | 104 | 489 | Region | Note=Calmodulin-binding |
| Tgene | >DAPK2 | chr15:63988323 | chr15:64263760 | ENST00000558069 | - | 2 | 10 | 292_301 | 104 | 489 | Region | Autoinhibitory domain |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >HERC1 | chr15:63988323 | chr15:64263760 | ENST00000443617 | - | 27 | 78 | 2002_2193 | 1707 | 4862 | Domain | B30.2/SPRY |
| Hgene | >HERC1 | chr15:63988323 | chr15:64263760 | ENST00000443617 | - | 27 | 78 | 4501_4848 | 1707 | 4862 | Domain | HECT |
| Hgene | >HERC1 | chr15:63988323 | chr15:64263760 | ENST00000443617 | - | 27 | 78 | 3426_3465 | 1707 | 4862 | Repeat | Note=WD 1 |
| Hgene | >HERC1 | chr15:63988323 | chr15:64263760 | ENST00000443617 | - | 27 | 78 | 3484_3522 | 1707 | 4862 | Repeat | Note=WD 2 |
| Hgene | >HERC1 | chr15:63988323 | chr15:64263760 | ENST00000443617 | - | 27 | 78 | 3524_3572 | 1707 | 4862 | Repeat | Note=WD 3 |
| Hgene | >HERC1 | chr15:63988323 | chr15:64263760 | ENST00000443617 | - | 27 | 78 | 3580_3619 | 1707 | 4862 | Repeat | Note=WD 4 |
| Hgene | >HERC1 | chr15:63988323 | chr15:64263760 | ENST00000443617 | - | 27 | 78 | 3624_3663 | 1707 | 4862 | Repeat | Note=WD 5 |
| Hgene | >HERC1 | chr15:63988323 | chr15:64263760 | ENST00000443617 | - | 27 | 78 | 3667_3713 | 1707 | 4862 | Repeat | Note=WD 6 |
| Hgene | >HERC1 | chr15:63988323 | chr15:64263760 | ENST00000443617 | - | 27 | 78 | 3745_3784 | 1707 | 4862 | Repeat | Note=WD 7 |
| Hgene | >HERC1 | chr15:63988323 | chr15:64263760 | ENST00000443617 | - | 27 | 78 | 3996_4044 | 1707 | 4862 | Repeat | Note=RCC1 8 |
| Hgene | >HERC1 | chr15:63988323 | chr15:64263760 | ENST00000443617 | - | 27 | 78 | 4046_4099 | 1707 | 4862 | Repeat | Note=RCC1 9 |
| Hgene | >HERC1 | chr15:63988323 | chr15:64263760 | ENST00000443617 | - | 27 | 78 | 4101_4151 | 1707 | 4862 | Repeat | Note=RCC1 10 |
| Hgene | >HERC1 | chr15:63988323 | chr15:64263760 | ENST00000443617 | - | 27 | 78 | 4153_4203 | 1707 | 4862 | Repeat | Note=RCC1 11 |
| Hgene | >HERC1 | chr15:63988323 | chr15:64263760 | ENST00000443617 | - | 27 | 78 | 4205_4256 | 1707 | 4862 | Repeat | Note=RCC1 12 |
| Hgene | >HERC1 | chr15:63988323 | chr15:64263760 | ENST00000443617 | - | 27 | 78 | 4258_4308 | 1707 | 4862 | Repeat | Note=RCC1 13 |
| Hgene | >HERC1 | chr15:63988323 | chr15:64263760 | ENST00000443617 | - | 27 | 78 | 4310_4360 | 1707 | 4862 | Repeat | Note=RCC1 14 |
| Tgene | DAPK2 | chr15:63988323 | chr15:64263760 | ENST00000261891 | - | 1 | 11 | 23_285 | 104 | 371 | Domain | Protein kinase |
| Tgene | DAPK2 | chr15:63988323 | chr15:64263760 | ENST00000457488 | - | 2 | 12 | 23_285 | 104 | 371 | Domain | Protein kinase |
| Tgene | DAPK2 | chr15:63988323 | chr15:64263760 | ENST00000558069 | - | 2 | 10 | 23_285 | 104 | 489 | Domain | Protein kinase |
| Tgene | DAPK2 | chr15:63988323 | chr15:64263760 | ENST00000261891 | - | 1 | 11 | 29_37 | 104 | 371 | Nucleotide binding | ATP |
| Tgene | DAPK2 | chr15:63988323 | chr15:64263760 | ENST00000457488 | - | 2 | 12 | 29_37 | 104 | 371 | Nucleotide binding | ATP |
| Tgene | DAPK2 | chr15:63988323 | chr15:64263760 | ENST00000558069 | - | 2 | 10 | 29_37 | 104 | 489 | Nucleotide binding | ATP |
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FusionGeneSequence for HERC1_DAPK2 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_HERC1_ENST00000443617_chr15_63988323_-_DAPK2_ENST00000261891_chr15_64263760_-_1973aa MATMIPPVKLKWLEHLNSSWITEDSESIATREGVAVLYSKLVSNKEVVPLPQQVLCLKGPQLPDFERESLSSDEQDHYLDALLSSQLALA KMVCSDSPFAGALRKRLLVLQRVFYALSNKYHDKGKVKQQQHSPESSSGSADVHSVSERPRSSTDALIEMGVRTGLSLLFALLRQSWMMP VSGPGLSLCNDVIHTAIEVVSSLPPLSLANESKIPPMGLDCLSQVTTFLKGVTIPNSGADTLGRRLASELLLGLAAQRGSLRYLLEWIEM ALGASAVVHTMEKGKLLSSQEGMISFDCFMTILMQMRRSLGSSADRSQWREPTRTSDGLCSLYEAALCLFEEVCRMASDYSRTCASPDSI QTGDAPIVSETCEVYVWGSNSSHQLVEGTQEKILQPKLAPSFSDAQTIEAGQYCTFVISTDGSVRACGKGSYGRLGLGDSNNQSTLKKLT FEPHRSIKKVSSSKGSDGHTLAFTTEGEVFSWGDGDYGKLGHGNSSTQKYPKLIQGPLQGKVVVCVSAGYRHSAAVTEDGELYTWGEGDF GRLGHGDSNSRNIPTLVKDISNVGEVSCGSSHTIALSKDGRTVWSFGGGDNGKLGHGDTNRVYKPKVIEALQGMFIRKVCAGSQSSLALT STGQVYAWGCGACLGCGSSEATALRPKLIEELAATRIVDVSIGDSHCLALSHDNEVYAWGNNSMGQCGQGNSTGPITKPKKVSGLDGIAI QQISAGTSHSLAWTALPRDRQVVAWHRPYCVDLEESTFSHLRSFLERYCDKINSEIPPLPFPSSREHHSFLKLCLKLLSNHLALALAGGV ATSILGRQAGPLRNLLFRLMDSTVPDEIQEVVIETLSVGATMLLPPLRERMELLHSLLPQGPDRWESLSKGQRMQLDIILTSLQDHTHVA SLLGYSSPSDAADLSSVCTGYGNLSDQPYGTQSCHPDTHLAEILMKTLLRNLGFYTDQAFGELEKNSDKFLLGTSSSENSQPAHLHELLC SLQKQLLAFCHINNISENSSSVALLHKHLQLLLPHATDIYSRSANLLKESPWNGSVGEKLRDVIYVSAAGSMLCQIVNSLLLLPVSVARP LLSYLLDLLPPLDCLNRLLPAADLLEDQELQWPLHGGPELIDPAGLPLPQPAQSWVWLVDLERTIALLIGRCLGGMLQGSPVSPEEQDTA YWMKTPLFSDGVEMDTPQLDKCMSCLLEVALSGNEEQKPFDYKLRPEIAVYVDLALGCSKEPARSLWISMQDYAVSKDWDSATLSNESLL DTVSRFVLAALLKHTNLLSQACGESRYQPGKHLSEVYRCVYKVRSRLLACKNLELIQTRSSSRDRWISENQDSADVDPQEHSFTRTIDEE AEMEEQAERDREEGHPEPEDEEEEREHEVMTAGKIFQCFLSAREVARSRDRDRMNSGAGSGARADDPPPQSQQERRVSTDLPEGQDVYTA ACNSVIHRCALLILGVSPVIDELQKRREEGQLQQPSTSASEGGGLMTRSESLTAESRLVHTSPNYRLIKSRSESDLSQPESDEEGYALSG RRNVDLDLAASHRKRGPMHSQLESLSDSWARLKHSRDWLCNSSYSFESDFDLTKSLGVHTLIENVVSFVSGDVGNAPGFKEPEESMSTSP QASIIAMEQQQLRAELRLEALHQILVLLSGMEEKGSISLAGSRLSSGFQSSTLLTSVRLQFLAGCFGLGTVGHTGGKGESGRLHHYQSVW RRALRFPGPEGVTEXGGGHQLHXADPGWGELPSHKENCSLXSQARKHYVVRQEYSHSTHQADXLWSGSRNRRWSXIXEYFWDAGICCSRN CELRAPGSGGXHVEHRRHHLHPLKWSIPFPGRHEAGNTGKYHSSELRLXXGILQPDERAGQGLYSEASGXRDPETAHNPRGSQTPLDHAG >In-frame_HERC1_ENST00000443617_chr15_63988323_-_DAPK2_ENST00000457488_chr15_64263760_-_1973aa MATMIPPVKLKWLEHLNSSWITEDSESIATREGVAVLYSKLVSNKEVVPLPQQVLCLKGPQLPDFERESLSSDEQDHYLDALLSSQLALA KMVCSDSPFAGALRKRLLVLQRVFYALSNKYHDKGKVKQQQHSPESSSGSADVHSVSERPRSSTDALIEMGVRTGLSLLFALLRQSWMMP VSGPGLSLCNDVIHTAIEVVSSLPPLSLANESKIPPMGLDCLSQVTTFLKGVTIPNSGADTLGRRLASELLLGLAAQRGSLRYLLEWIEM ALGASAVVHTMEKGKLLSSQEGMISFDCFMTILMQMRRSLGSSADRSQWREPTRTSDGLCSLYEAALCLFEEVCRMASDYSRTCASPDSI QTGDAPIVSETCEVYVWGSNSSHQLVEGTQEKILQPKLAPSFSDAQTIEAGQYCTFVISTDGSVRACGKGSYGRLGLGDSNNQSTLKKLT FEPHRSIKKVSSSKGSDGHTLAFTTEGEVFSWGDGDYGKLGHGNSSTQKYPKLIQGPLQGKVVVCVSAGYRHSAAVTEDGELYTWGEGDF GRLGHGDSNSRNIPTLVKDISNVGEVSCGSSHTIALSKDGRTVWSFGGGDNGKLGHGDTNRVYKPKVIEALQGMFIRKVCAGSQSSLALT STGQVYAWGCGACLGCGSSEATALRPKLIEELAATRIVDVSIGDSHCLALSHDNEVYAWGNNSMGQCGQGNSTGPITKPKKVSGLDGIAI QQISAGTSHSLAWTALPRDRQVVAWHRPYCVDLEESTFSHLRSFLERYCDKINSEIPPLPFPSSREHHSFLKLCLKLLSNHLALALAGGV ATSILGRQAGPLRNLLFRLMDSTVPDEIQEVVIETLSVGATMLLPPLRERMELLHSLLPQGPDRWESLSKGQRMQLDIILTSLQDHTHVA SLLGYSSPSDAADLSSVCTGYGNLSDQPYGTQSCHPDTHLAEILMKTLLRNLGFYTDQAFGELEKNSDKFLLGTSSSENSQPAHLHELLC SLQKQLLAFCHINNISENSSSVALLHKHLQLLLPHATDIYSRSANLLKESPWNGSVGEKLRDVIYVSAAGSMLCQIVNSLLLLPVSVARP LLSYLLDLLPPLDCLNRLLPAADLLEDQELQWPLHGGPELIDPAGLPLPQPAQSWVWLVDLERTIALLIGRCLGGMLQGSPVSPEEQDTA YWMKTPLFSDGVEMDTPQLDKCMSCLLEVALSGNEEQKPFDYKLRPEIAVYVDLALGCSKEPARSLWISMQDYAVSKDWDSATLSNESLL DTVSRFVLAALLKHTNLLSQACGESRYQPGKHLSEVYRCVYKVRSRLLACKNLELIQTRSSSRDRWISENQDSADVDPQEHSFTRTIDEE AEMEEQAERDREEGHPEPEDEEEEREHEVMTAGKIFQCFLSAREVARSRDRDRMNSGAGSGARADDPPPQSQQERRVSTDLPEGQDVYTA ACNSVIHRCALLILGVSPVIDELQKRREEGQLQQPSTSASEGGGLMTRSESLTAESRLVHTSPNYRLIKSRSESDLSQPESDEEGYALSG RRNVDLDLAASHRKRGPMHSQLESLSDSWARLKHSRDWLCNSSYSFESDFDLTKSLGVHTLIENVVSFVSGDVGNAPGFKEPEESMSTSP QASIIAMEQQQLRAELRLEALHQILVLLSGMEEKGSISLAGSRLSSGFQSSTLLTSVRLQFLAGCFGLGTVGHTGGKGESGRLHHYQSVW RRALRFPGPEGVTEXGGGHQLHXADPGWGELPSHKENCSLXSQARKHYVVRQEYSHSTHQADXLWSGSRNRRWSXIXEYFWDAGICCSRN CELRAPGSGGXHVEHRRHHLHPLKWSIPFPGRHEAGNTGKYHSSELRLXXGILQPDERAGQGLYSEASGXRDPETAHNPRGSQTPLDHAG >In-frame_HERC1_ENST00000443617_chr15_63988323_-_DAPK2_ENST00000558069_chr15_64263760_-_2091aa MATMIPPVKLKWLEHLNSSWITEDSESIATREGVAVLYSKLVSNKEVVPLPQQVLCLKGPQLPDFERESLSSDEQDHYLDALLSSQLALA KMVCSDSPFAGALRKRLLVLQRVFYALSNKYHDKGKVKQQQHSPESSSGSADVHSVSERPRSSTDALIEMGVRTGLSLLFALLRQSWMMP VSGPGLSLCNDVIHTAIEVVSSLPPLSLANESKIPPMGLDCLSQVTTFLKGVTIPNSGADTLGRRLASELLLGLAAQRGSLRYLLEWIEM ALGASAVVHTMEKGKLLSSQEGMISFDCFMTILMQMRRSLGSSADRSQWREPTRTSDGLCSLYEAALCLFEEVCRMASDYSRTCASPDSI QTGDAPIVSETCEVYVWGSNSSHQLVEGTQEKILQPKLAPSFSDAQTIEAGQYCTFVISTDGSVRACGKGSYGRLGLGDSNNQSTLKKLT FEPHRSIKKVSSSKGSDGHTLAFTTEGEVFSWGDGDYGKLGHGNSSTQKYPKLIQGPLQGKVVVCVSAGYRHSAAVTEDGELYTWGEGDF GRLGHGDSNSRNIPTLVKDISNVGEVSCGSSHTIALSKDGRTVWSFGGGDNGKLGHGDTNRVYKPKVIEALQGMFIRKVCAGSQSSLALT STGQVYAWGCGACLGCGSSEATALRPKLIEELAATRIVDVSIGDSHCLALSHDNEVYAWGNNSMGQCGQGNSTGPITKPKKVSGLDGIAI QQISAGTSHSLAWTALPRDRQVVAWHRPYCVDLEESTFSHLRSFLERYCDKINSEIPPLPFPSSREHHSFLKLCLKLLSNHLALALAGGV ATSILGRQAGPLRNLLFRLMDSTVPDEIQEVVIETLSVGATMLLPPLRERMELLHSLLPQGPDRWESLSKGQRMQLDIILTSLQDHTHVA SLLGYSSPSDAADLSSVCTGYGNLSDQPYGTQSCHPDTHLAEILMKTLLRNLGFYTDQAFGELEKNSDKFLLGTSSSENSQPAHLHELLC SLQKQLLAFCHINNISENSSSVALLHKHLQLLLPHATDIYSRSANLLKESPWNGSVGEKLRDVIYVSAAGSMLCQIVNSLLLLPVSVARP LLSYLLDLLPPLDCLNRLLPAADLLEDQELQWPLHGGPELIDPAGLPLPQPAQSWVWLVDLERTIALLIGRCLGGMLQGSPVSPEEQDTA YWMKTPLFSDGVEMDTPQLDKCMSCLLEVALSGNEEQKPFDYKLRPEIAVYVDLALGCSKEPARSLWISMQDYAVSKDWDSATLSNESLL DTVSRFVLAALLKHTNLLSQACGESRYQPGKHLSEVYRCVYKVRSRLLACKNLELIQTRSSSRDRWISENQDSADVDPQEHSFTRTIDEE AEMEEQAERDREEGHPEPEDEEEEREHEVMTAGKIFQCFLSAREVARSRDRDRMNSGAGSGARADDPPPQSQQERRVSTDLPEGQDVYTA ACNSVIHRCALLILGVSPVIDELQKRREEGQLQQPSTSASEGGGLMTRSESLTAESRLVHTSPNYRLIKSRSESDLSQPESDEEGYALSG RRNVDLDLAASHRKRGPMHSQLESLSDSWARLKHSRDWLCNSSYSFESDFDLTKSLGVHTLIENVVSFVSGDVGNAPGFKEPEESMSTSP QASIIAMEQQQLRAELRLEALHQILVLLSGMEEKGSISLAGSRLSSGFQSSTLLTSVRLQFLAGCFGLGTVGHTGGKGESGRLHHYQSVW RRALRFPGPEGVTEXGGGHQLHXADPGWGELPSHKENCSLXSQARKHYVVRQEYSHSTHQADXLWSGSRNRRWSXIXEYFWDAGICCSRN CELRAPGSGGXHVEHRRHHLHPLKWSIPFPGRHEAGNTGKYHSSELRLXXGILQPDERAGQGLYSEASGXRDPETAHNPRGSQTPLDHVK RRRQSPXTAEDRAHPAEDQAPERVHSQMPLKHASQQLLCQLRAFCLCGGRRGSGRPGMPCPGGGPRYHPGRCGGPGLHLQXEGSLVPRGE XERPAXPVPAQVXVPQGGVIEEAAARRHPGHGMXPRKHGQETGPSASPVXDSEAGALRRPAVDSGAGGQLPAGEWELXGPGLHILPGHQX |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_HERC1_ENST00000443617_chr15_63988323_-_DAPK2_ENST00000261891_chr15_64263760_-_5920nt ATGGCAACTATGATTCCACCAGTGAAGCTGAAATGGCTTGAACACTTGAACAGCTCCTGGATTACAGAGGACAGTGAATCTATTGCTACA AGAGAGGGAGTTGCTGTTCTGTATTCTAAACTGGTTAGCAATAAGGAAGTAGTACCTTTGCCCCAACAAGTTTTATGCCTCAAAGGACCA CAGTTGCCAGACTTTGAACGTGAGTCTCTTTCAAGTGATGAGCAGGACCACTATTTGGATGCCCTTCTTAGCAGCCAGCTAGCATTGGCA AAGATGGTATGTTCAGATTCCCCATTTGCCGGGGCACTTAGAAAACGACTGCTTGTACTCCAGCGTGTCTTTTATGCACTTTCTAATAAA TACCATGACAAAGGCAAGGTGAAGCAGCAGCAGCATTCTCCGGAGAGCAGTTCTGGTTCAGCAGATGTCCATTCTGTTAGTGAACGCCCC CGGTCAAGCACTGATGCACTTATAGAAATGGGTGTTCGAACTGGTCTAAGTTTATTATTTGCGCTTCTAAGACAAAGTTGGATGATGCCT GTGTCAGGACCTGGTCTCAGTCTTTGCAACGATGTCATTCATACTGCAATTGAAGTTGTGAGCTCTTTGCCACCATTATCATTAGCAAAT GAAAGCAAGATTCCTCCTATGGGCTTGGACTGCTTATCGCAAGTAACAACATTTCTTAAAGGAGTCACTATTCCTAATTCTGGGGCAGAC ACTTTAGGTCGTAGATTAGCTTCTGAGTTGCTGCTTGGTTTGGCAGCTCAACGAGGCTCATTGCGATATCTTCTTGAATGGATAGAAATG GCTTTGGGGGCTTCGGCAGTTGTACACACCATGGAGAAAGGCAAACTACTCTCAAGCCAGGAAGGAATGATCAGCTTTGACTGCTTTATG ACCATATTAATGCAGATGAGGCGTTCTTTGGGTTCATCTGCTGATCGGAGTCAGTGGAGAGAACCAACCAGAACATCGGATGGCTTGTGC TCCCTTTACGAGGCAGCATTATGTCTCTTTGAAGAGGTTTGCAGAATGGCTTCTGATTATTCGAGAACATGTGCTAGCCCAGATAGCATT CAGACTGGTGATGCTCCCATTGTCTCCGAAACCTGTGAGGTTTATGTTTGGGGGAGCAATAGCAGCCATCAGTTGGTAGAAGGTACACAG GAGAAAATACTGCAACCCAAACTGGCTCCTAGTTTCTCTGATGCACAGACCATTGAAGCTGGACAGTACTGCACTTTTGTCATTTCTACG GATGGCTCTGTTAGAGCTTGCGGGAAAGGCAGCTATGGGAGACTGGGCCTTGGAGACTCCAATAATCAGTCAACTTTAAAAAAGTTAACA TTCGAGCCTCACAGATCCATTAAAAAGGTTTCATCTTCTAAAGGATCTGATGGTCACACTTTAGCCTTTACGACAGAAGGAGAAGTCTTC AGTTGGGGAGATGGTGATTATGGGAAACTGGGGCATGGAAATAGTTCAACACAGAAATATCCCAAGCTTATTCAGGGACCTCTACAAGGA AAGGTAGTTGTTTGTGTGTCAGCTGGATACAGACATAGTGCTGCTGTCACAGAGGATGGGGAATTATACACATGGGGTGAAGGAGACTTT GGAAGATTAGGTCATGGTGACAGCAATAGTCGTAACATTCCAACATTAGTAAAAGACATCAGCAATGTAGGAGAGGTTTCTTGTGGCAGT TCACATACTATTGCTCTGTCTAAAGATGGGAGAACTGTATGGTCTTTTGGAGGAGGAGACAATGGTAAACTTGGTCATGGTGATACCAAC AGAGTGTATAAACCTAAAGTTATTGAAGCTTTACAAGGAATGTTCATTCGCAAAGTTTGTGCTGGGAGCCAGTCTTCACTTGCTTTGACA TCAACAGGGCAGGTCTATGCTTGGGGCTGTGGAGCTTGTCTAGGTTGTGGTTCTTCAGAAGCTACTGCTTTGAGACCCAAGCTTATTGAA GAACTGGCTGCCACAAGAATAGTTGATGTTTCTATTGGAGACAGTCATTGTTTGGCTCTTTCTCATGATAATGAAGTTTATGCCTGGGGC AATAACTCAATGGGGCAATGTGGTCAGGGAAATTCCACAGGTCCTATTACTAAACCAAAGAAAGTGAGTGGCTTAGATGGCATAGCTATT CAGCAGATTTCGGCTGGAACATCACATAGTCTGGCATGGACTGCTCTTCCTAGGGACAGACAAGTTGTTGCATGGCACCGACCTTATTGT GTAGATCTTGAAGAGAGTACCTTCTCACACCTGCGTTCTTTTCTTGAGAGATACTGTGATAAAATAAACAGTGAGATTCCCCCACTCCCT TTCCCTTCATCAAGAGAACACCACAGTTTTCTCAAGCTGTGCCTGAAGCTACTTTCAAATCACCTTGCTCTTGCACTTGCGGGAGGGGTA GCTACCAGCATTCTCGGGAGGCAGGCAGGTCCACTTCGAAATTTGCTCTTCAGACTGATGGACTCAACTGTCCCAGATGAAATCCAAGAG GTGGTAATTGAAACTTTATCAGTGGGAGCAACCATGCTGTTACCTCCATTACGAGAACGGATGGAATTACTTCATTCTCTTTTACCTCAA GGACCTGATAGATGGGAAAGCTTATCTAAAGGACAGAGAATGCAACTGGATATCATCCTGACAAGTTTGCAAGATCATACCCACGTAGCC TCCCTACTTGGCTATAGTTCACCCTCTGATGCTGCTGACCTATCTTCTGTGTGTACTGGCTACGGAAATCTGTCAGATCAACCTTACGGC ACTCAGAGCTGCCATCCAGATACCCACCTGGCTGAAATTTTGATGAAGACCCTCTTAAGAAATTTAGGATTTTATACAGATCAAGCATTT GGAGAGCTAGAAAAGAATAGTGATAAATTTCTACTTGGAACATCATCATCAGAAAACAGTCAGCCTGCTCATCTTCATGAACTGCTATGT TCACTACAGAAACAGCTGCTGGCATTTTGCCATATCAATAACATTAGTGAGAACTCAAGCAGTGTGGCATTGCTTCATAAACATCTTCAG CTTTTGTTGCCTCATGCCACAGATATTTATTCACGTTCTGCAAATTTGCTCAAAGAAAGTCCTTGGAATGGCAGTGTTGGAGAAAAATTA AGAGATGTGATATACGTCTCAGCTGCTGGCAGTATGCTCTGCCAGATTGTTAACTCCCTGCTGTTACTCCCTGTGTCAGTGGCTCGGCCT TTATTGAGTTACCTCCTCGACTTGTTGCCACCTCTTGATTGCCTTAATAGACTCCTGCCAGCTGCTGATCTTTTAGAAGACCAGGAGTTA CAGTGGCCTCTTCATGGAGGGCCAGAACTAATTGATCCTGCTGGTCTGCCATTACCTCAGCCAGCTCAGTCCTGGGTATGGCTTGTGGAT CTAGAAAGAACAATTGCTCTCCTTATTGGGCGGTGTCTTGGTGGCATGCTTCAGGGCTCCCCTGTGTCTCCAGAGGAACAGGACACTGCA TATTGGATGAAAACGCCACTGTTCAGTGACGGTGTAGAAATGGACACTCCTCAATTGGATAAATGTATGAGTTGCCTGTTAGAAGTAGCA CTTTCTGGAAATGAAGAACAGAAGCCTTTTGATTATAAATTGCGGCCTGAAATTGCTGTCTATGTAGACTTGGCATTGGGTTGTTCTAAA GAGCCTGCCCGAAGCCTTTGGATCAGCATGCAGGACTATGCTGTTAGTAAAGATTGGGACAGTGCAACTTTAAGTAATGAGTCACTCTTG GACACTGTGTCTAGATTTGTTCTTGCAGCTCTTCTGAAACACACAAATTTACTTAGTCAAGCATGTGGAGAAAGCCGATATCAACCTGGT AAACACTTATCAGAAGTGTACCGTTGTGTATACAAAGTTCGAAGTCGTTTACTTGCTTGCAAGAACCTTGAACTTATTCAAACAAGGTCA TCATCACGGGACAGATGGATATCAGAAAACCAGGACTCTGCAGATGTTGATCCTCAGGAGCATTCATTTACTCGAACTATTGATGAAGAA GCTGAAATGGAAGAACAGGCTGAGAGAGACCGGGAAGAGGGGCATCCGGAGCCAGAGGATGAAGAGGAGGAACGGGAACATGAAGTGATG ACAGCTGGCAAAATCTTTCAGTGTTTCCTCTCAGCCCGTGAAGTAGCTCGTAGCCGAGACCGAGATAGAATGAACAGTGGGGCAGGGTCT GGGGCTCGAGCTGATGATCCACCTCCTCAGTCTCAGCAAGAGCGAAGGGTCAGCACAGACCTTCCTGAGGGTCAGGATGTGTACACTGCT GCATGCAACTCCGTGATCCATCGGTGTGCCCTGTTAATATTAGGAGTAAGTCCTGTGATAGATGAGCTTCAGAAGCGAAGAGAAGAAGGA CAGTTGCAGCAACCTTCAACAAGTGCCTCTGAAGGGGGTGGACTTATGACCAGGAGTGAAAGTCTTACTGCAGAGAGCCGGCTAGTCCAC ACAAGCCCAAATTATAGACTGATCAAATCGAGGAGTGAATCTGATTTGTCTCAGCCTGAATCAGATGAAGAGGGTTACGCACTGAGTGGC AGACGAAATGTTGATTTGGATTTGGCAGCATCTCACAGAAAGAGAGGTCCTATGCACAGTCAATTGGAATCCCTGAGTGACTCTTGGGCT CGCCTGAAACATAGCAGAGACTGGTTATGCAACTCCTCCTATTCCTTTGAGTCAGATTTTGATCTTACCAAGTCTTTGGGAGTTCACACT TTGATTGAAAATGTTGTAAGCTTTGTGAGTGGAGATGTGGGGAATGCCCCAGGTTTTAAAGAGCCAGAGGAAAGTATGTCTACAAGTCCC CAGGCCTCCATCATTGCAATGGAACAGCAGCAGTTAAGGGCAGAACTTCGTTTAGAGGCACTTCATCAGATCCTCGTTCTATTGTCTGGG ATGGAAGAAAAAGGTAGCATCTCACTGGCAGGAAGCAGATTGAGTTCAGGCTTCCAGTCCTCCACACTACTCACGTCTGTGAGGCTGCAG TTCCTAGCAGGGTGTTTTGGTTTAGGCACTGTTGGACACACAGGAGGCAAGGGAGAGAGTGGCCGATTGCATCACTATCAGAGTGTCTGG AGGAGAGCTCTTCGATTTCCTGGCCCAGAAGGAGTCACTGAGTGAGGAGGAGGCCACCAGCTTCATTAAGCAGATCCTGGATGGGGTGAA CTACCTTCACACAAAGAAAATTGCTCACTTTGATCTCAAGCCAGAAAACATTATGTTGTTAGACAAGAATATTCCCATTCCACACATCAA GCTGATTGACTTTGGTCTGGCTCACGAAATAGAAGATGGAGTTGAATTTAAGAATATTTTTGGGACGCCGGAATTTGTTGCTCCAGAAAT TGTGAACTACGAGCCCCTGGGTCTGGAGGCTGACATGTGGAGCATAGGCGTCATCACCTACATCCTCTTAAGTGGAGCATCCCCTTTCCT GGGAGACACGAAGCAGGAAACACTGGCAAATATCACAGCAGTGAGTTACGACTTTGATGAGGAATTCTTCAGCCAGACGAGCGAGCTGGC CAAGGACTTTATTCGGAAGCTTCTGGTTAAAGAGACCCGGAAACGGCTCACAATCCAAGAGGCTCTCAGACACCCCTGGATCACGCCGGT GGACAACCAGCAAGCCATGGTGCGCAGGGAGTCTGTGGTCAATCTGGAGAACTTCAGGAAGCAGTATGTCCGCAGGCGGTGGAAGCTTTC CTTCAGCATCGTGTCCCTGTGCAACCACCTCACCCGCTCGCTGATGAAGAAGGTGCACCTGAGGCCGGATGAGGACCTGAGGAACTGTGA >In-frame_HERC1_ENST00000443617_chr15_63988323_-_DAPK2_ENST00000457488_chr15_64263760_-_5920nt ATGGCAACTATGATTCCACCAGTGAAGCTGAAATGGCTTGAACACTTGAACAGCTCCTGGATTACAGAGGACAGTGAATCTATTGCTACA AGAGAGGGAGTTGCTGTTCTGTATTCTAAACTGGTTAGCAATAAGGAAGTAGTACCTTTGCCCCAACAAGTTTTATGCCTCAAAGGACCA CAGTTGCCAGACTTTGAACGTGAGTCTCTTTCAAGTGATGAGCAGGACCACTATTTGGATGCCCTTCTTAGCAGCCAGCTAGCATTGGCA AAGATGGTATGTTCAGATTCCCCATTTGCCGGGGCACTTAGAAAACGACTGCTTGTACTCCAGCGTGTCTTTTATGCACTTTCTAATAAA TACCATGACAAAGGCAAGGTGAAGCAGCAGCAGCATTCTCCGGAGAGCAGTTCTGGTTCAGCAGATGTCCATTCTGTTAGTGAACGCCCC CGGTCAAGCACTGATGCACTTATAGAAATGGGTGTTCGAACTGGTCTAAGTTTATTATTTGCGCTTCTAAGACAAAGTTGGATGATGCCT GTGTCAGGACCTGGTCTCAGTCTTTGCAACGATGTCATTCATACTGCAATTGAAGTTGTGAGCTCTTTGCCACCATTATCATTAGCAAAT GAAAGCAAGATTCCTCCTATGGGCTTGGACTGCTTATCGCAAGTAACAACATTTCTTAAAGGAGTCACTATTCCTAATTCTGGGGCAGAC ACTTTAGGTCGTAGATTAGCTTCTGAGTTGCTGCTTGGTTTGGCAGCTCAACGAGGCTCATTGCGATATCTTCTTGAATGGATAGAAATG GCTTTGGGGGCTTCGGCAGTTGTACACACCATGGAGAAAGGCAAACTACTCTCAAGCCAGGAAGGAATGATCAGCTTTGACTGCTTTATG ACCATATTAATGCAGATGAGGCGTTCTTTGGGTTCATCTGCTGATCGGAGTCAGTGGAGAGAACCAACCAGAACATCGGATGGCTTGTGC TCCCTTTACGAGGCAGCATTATGTCTCTTTGAAGAGGTTTGCAGAATGGCTTCTGATTATTCGAGAACATGTGCTAGCCCAGATAGCATT CAGACTGGTGATGCTCCCATTGTCTCCGAAACCTGTGAGGTTTATGTTTGGGGGAGCAATAGCAGCCATCAGTTGGTAGAAGGTACACAG GAGAAAATACTGCAACCCAAACTGGCTCCTAGTTTCTCTGATGCACAGACCATTGAAGCTGGACAGTACTGCACTTTTGTCATTTCTACG GATGGCTCTGTTAGAGCTTGCGGGAAAGGCAGCTATGGGAGACTGGGCCTTGGAGACTCCAATAATCAGTCAACTTTAAAAAAGTTAACA TTCGAGCCTCACAGATCCATTAAAAAGGTTTCATCTTCTAAAGGATCTGATGGTCACACTTTAGCCTTTACGACAGAAGGAGAAGTCTTC AGTTGGGGAGATGGTGATTATGGGAAACTGGGGCATGGAAATAGTTCAACACAGAAATATCCCAAGCTTATTCAGGGACCTCTACAAGGA AAGGTAGTTGTTTGTGTGTCAGCTGGATACAGACATAGTGCTGCTGTCACAGAGGATGGGGAATTATACACATGGGGTGAAGGAGACTTT GGAAGATTAGGTCATGGTGACAGCAATAGTCGTAACATTCCAACATTAGTAAAAGACATCAGCAATGTAGGAGAGGTTTCTTGTGGCAGT TCACATACTATTGCTCTGTCTAAAGATGGGAGAACTGTATGGTCTTTTGGAGGAGGAGACAATGGTAAACTTGGTCATGGTGATACCAAC AGAGTGTATAAACCTAAAGTTATTGAAGCTTTACAAGGAATGTTCATTCGCAAAGTTTGTGCTGGGAGCCAGTCTTCACTTGCTTTGACA TCAACAGGGCAGGTCTATGCTTGGGGCTGTGGAGCTTGTCTAGGTTGTGGTTCTTCAGAAGCTACTGCTTTGAGACCCAAGCTTATTGAA GAACTGGCTGCCACAAGAATAGTTGATGTTTCTATTGGAGACAGTCATTGTTTGGCTCTTTCTCATGATAATGAAGTTTATGCCTGGGGC AATAACTCAATGGGGCAATGTGGTCAGGGAAATTCCACAGGTCCTATTACTAAACCAAAGAAAGTGAGTGGCTTAGATGGCATAGCTATT CAGCAGATTTCGGCTGGAACATCACATAGTCTGGCATGGACTGCTCTTCCTAGGGACAGACAAGTTGTTGCATGGCACCGACCTTATTGT GTAGATCTTGAAGAGAGTACCTTCTCACACCTGCGTTCTTTTCTTGAGAGATACTGTGATAAAATAAACAGTGAGATTCCCCCACTCCCT TTCCCTTCATCAAGAGAACACCACAGTTTTCTCAAGCTGTGCCTGAAGCTACTTTCAAATCACCTTGCTCTTGCACTTGCGGGAGGGGTA GCTACCAGCATTCTCGGGAGGCAGGCAGGTCCACTTCGAAATTTGCTCTTCAGACTGATGGACTCAACTGTCCCAGATGAAATCCAAGAG GTGGTAATTGAAACTTTATCAGTGGGAGCAACCATGCTGTTACCTCCATTACGAGAACGGATGGAATTACTTCATTCTCTTTTACCTCAA GGACCTGATAGATGGGAAAGCTTATCTAAAGGACAGAGAATGCAACTGGATATCATCCTGACAAGTTTGCAAGATCATACCCACGTAGCC TCCCTACTTGGCTATAGTTCACCCTCTGATGCTGCTGACCTATCTTCTGTGTGTACTGGCTACGGAAATCTGTCAGATCAACCTTACGGC ACTCAGAGCTGCCATCCAGATACCCACCTGGCTGAAATTTTGATGAAGACCCTCTTAAGAAATTTAGGATTTTATACAGATCAAGCATTT GGAGAGCTAGAAAAGAATAGTGATAAATTTCTACTTGGAACATCATCATCAGAAAACAGTCAGCCTGCTCATCTTCATGAACTGCTATGT TCACTACAGAAACAGCTGCTGGCATTTTGCCATATCAATAACATTAGTGAGAACTCAAGCAGTGTGGCATTGCTTCATAAACATCTTCAG CTTTTGTTGCCTCATGCCACAGATATTTATTCACGTTCTGCAAATTTGCTCAAAGAAAGTCCTTGGAATGGCAGTGTTGGAGAAAAATTA AGAGATGTGATATACGTCTCAGCTGCTGGCAGTATGCTCTGCCAGATTGTTAACTCCCTGCTGTTACTCCCTGTGTCAGTGGCTCGGCCT TTATTGAGTTACCTCCTCGACTTGTTGCCACCTCTTGATTGCCTTAATAGACTCCTGCCAGCTGCTGATCTTTTAGAAGACCAGGAGTTA CAGTGGCCTCTTCATGGAGGGCCAGAACTAATTGATCCTGCTGGTCTGCCATTACCTCAGCCAGCTCAGTCCTGGGTATGGCTTGTGGAT CTAGAAAGAACAATTGCTCTCCTTATTGGGCGGTGTCTTGGTGGCATGCTTCAGGGCTCCCCTGTGTCTCCAGAGGAACAGGACACTGCA TATTGGATGAAAACGCCACTGTTCAGTGACGGTGTAGAAATGGACACTCCTCAATTGGATAAATGTATGAGTTGCCTGTTAGAAGTAGCA CTTTCTGGAAATGAAGAACAGAAGCCTTTTGATTATAAATTGCGGCCTGAAATTGCTGTCTATGTAGACTTGGCATTGGGTTGTTCTAAA GAGCCTGCCCGAAGCCTTTGGATCAGCATGCAGGACTATGCTGTTAGTAAAGATTGGGACAGTGCAACTTTAAGTAATGAGTCACTCTTG GACACTGTGTCTAGATTTGTTCTTGCAGCTCTTCTGAAACACACAAATTTACTTAGTCAAGCATGTGGAGAAAGCCGATATCAACCTGGT AAACACTTATCAGAAGTGTACCGTTGTGTATACAAAGTTCGAAGTCGTTTACTTGCTTGCAAGAACCTTGAACTTATTCAAACAAGGTCA TCATCACGGGACAGATGGATATCAGAAAACCAGGACTCTGCAGATGTTGATCCTCAGGAGCATTCATTTACTCGAACTATTGATGAAGAA GCTGAAATGGAAGAACAGGCTGAGAGAGACCGGGAAGAGGGGCATCCGGAGCCAGAGGATGAAGAGGAGGAACGGGAACATGAAGTGATG ACAGCTGGCAAAATCTTTCAGTGTTTCCTCTCAGCCCGTGAAGTAGCTCGTAGCCGAGACCGAGATAGAATGAACAGTGGGGCAGGGTCT GGGGCTCGAGCTGATGATCCACCTCCTCAGTCTCAGCAAGAGCGAAGGGTCAGCACAGACCTTCCTGAGGGTCAGGATGTGTACACTGCT GCATGCAACTCCGTGATCCATCGGTGTGCCCTGTTAATATTAGGAGTAAGTCCTGTGATAGATGAGCTTCAGAAGCGAAGAGAAGAAGGA CAGTTGCAGCAACCTTCAACAAGTGCCTCTGAAGGGGGTGGACTTATGACCAGGAGTGAAAGTCTTACTGCAGAGAGCCGGCTAGTCCAC ACAAGCCCAAATTATAGACTGATCAAATCGAGGAGTGAATCTGATTTGTCTCAGCCTGAATCAGATGAAGAGGGTTACGCACTGAGTGGC AGACGAAATGTTGATTTGGATTTGGCAGCATCTCACAGAAAGAGAGGTCCTATGCACAGTCAATTGGAATCCCTGAGTGACTCTTGGGCT CGCCTGAAACATAGCAGAGACTGGTTATGCAACTCCTCCTATTCCTTTGAGTCAGATTTTGATCTTACCAAGTCTTTGGGAGTTCACACT TTGATTGAAAATGTTGTAAGCTTTGTGAGTGGAGATGTGGGGAATGCCCCAGGTTTTAAAGAGCCAGAGGAAAGTATGTCTACAAGTCCC CAGGCCTCCATCATTGCAATGGAACAGCAGCAGTTAAGGGCAGAACTTCGTTTAGAGGCACTTCATCAGATCCTCGTTCTATTGTCTGGG ATGGAAGAAAAAGGTAGCATCTCACTGGCAGGAAGCAGATTGAGTTCAGGCTTCCAGTCCTCCACACTACTCACGTCTGTGAGGCTGCAG TTCCTAGCAGGGTGTTTTGGTTTAGGCACTGTTGGACACACAGGAGGCAAGGGAGAGAGTGGCCGATTGCATCACTATCAGAGTGTCTGG AGGAGAGCTCTTCGATTTCCTGGCCCAGAAGGAGTCACTGAGTGAGGAGGAGGCCACCAGCTTCATTAAGCAGATCCTGGATGGGGTGAA CTACCTTCACACAAAGAAAATTGCTCACTTTGATCTCAAGCCAGAAAACATTATGTTGTTAGACAAGAATATTCCCATTCCACACATCAA GCTGATTGACTTTGGTCTGGCTCACGAAATAGAAGATGGAGTTGAATTTAAGAATATTTTTGGGACGCCGGAATTTGTTGCTCCAGAAAT TGTGAACTACGAGCCCCTGGGTCTGGAGGCTGACATGTGGAGCATAGGCGTCATCACCTACATCCTCTTAAGTGGAGCATCCCCTTTCCT GGGAGACACGAAGCAGGAAACACTGGCAAATATCACAGCAGTGAGTTACGACTTTGATGAGGAATTCTTCAGCCAGACGAGCGAGCTGGC CAAGGACTTTATTCGGAAGCTTCTGGTTAAAGAGACCCGGAAACGGCTCACAATCCAAGAGGCTCTCAGACACCCCTGGATCACGCCGGT GGACAACCAGCAAGCCATGGTGCGCAGGGAGTCTGTGGTCAATCTGGAGAACTTCAGGAAGCAGTATGTCCGCAGGCGGTGGAAGCTTTC CTTCAGCATCGTGTCCCTGTGCAACCACCTCACCCGCTCGCTGATGAAGAAGGTGCACCTGAGGCCGGATGAGGACCTGAGGAACTGTGA >In-frame_HERC1_ENST00000443617_chr15_63988323_-_DAPK2_ENST00000558069_chr15_64263760_-_6274nt ATGGCAACTATGATTCCACCAGTGAAGCTGAAATGGCTTGAACACTTGAACAGCTCCTGGATTACAGAGGACAGTGAATCTATTGCTACA AGAGAGGGAGTTGCTGTTCTGTATTCTAAACTGGTTAGCAATAAGGAAGTAGTACCTTTGCCCCAACAAGTTTTATGCCTCAAAGGACCA CAGTTGCCAGACTTTGAACGTGAGTCTCTTTCAAGTGATGAGCAGGACCACTATTTGGATGCCCTTCTTAGCAGCCAGCTAGCATTGGCA AAGATGGTATGTTCAGATTCCCCATTTGCCGGGGCACTTAGAAAACGACTGCTTGTACTCCAGCGTGTCTTTTATGCACTTTCTAATAAA TACCATGACAAAGGCAAGGTGAAGCAGCAGCAGCATTCTCCGGAGAGCAGTTCTGGTTCAGCAGATGTCCATTCTGTTAGTGAACGCCCC CGGTCAAGCACTGATGCACTTATAGAAATGGGTGTTCGAACTGGTCTAAGTTTATTATTTGCGCTTCTAAGACAAAGTTGGATGATGCCT GTGTCAGGACCTGGTCTCAGTCTTTGCAACGATGTCATTCATACTGCAATTGAAGTTGTGAGCTCTTTGCCACCATTATCATTAGCAAAT GAAAGCAAGATTCCTCCTATGGGCTTGGACTGCTTATCGCAAGTAACAACATTTCTTAAAGGAGTCACTATTCCTAATTCTGGGGCAGAC ACTTTAGGTCGTAGATTAGCTTCTGAGTTGCTGCTTGGTTTGGCAGCTCAACGAGGCTCATTGCGATATCTTCTTGAATGGATAGAAATG GCTTTGGGGGCTTCGGCAGTTGTACACACCATGGAGAAAGGCAAACTACTCTCAAGCCAGGAAGGAATGATCAGCTTTGACTGCTTTATG ACCATATTAATGCAGATGAGGCGTTCTTTGGGTTCATCTGCTGATCGGAGTCAGTGGAGAGAACCAACCAGAACATCGGATGGCTTGTGC TCCCTTTACGAGGCAGCATTATGTCTCTTTGAAGAGGTTTGCAGAATGGCTTCTGATTATTCGAGAACATGTGCTAGCCCAGATAGCATT CAGACTGGTGATGCTCCCATTGTCTCCGAAACCTGTGAGGTTTATGTTTGGGGGAGCAATAGCAGCCATCAGTTGGTAGAAGGTACACAG GAGAAAATACTGCAACCCAAACTGGCTCCTAGTTTCTCTGATGCACAGACCATTGAAGCTGGACAGTACTGCACTTTTGTCATTTCTACG GATGGCTCTGTTAGAGCTTGCGGGAAAGGCAGCTATGGGAGACTGGGCCTTGGAGACTCCAATAATCAGTCAACTTTAAAAAAGTTAACA TTCGAGCCTCACAGATCCATTAAAAAGGTTTCATCTTCTAAAGGATCTGATGGTCACACTTTAGCCTTTACGACAGAAGGAGAAGTCTTC AGTTGGGGAGATGGTGATTATGGGAAACTGGGGCATGGAAATAGTTCAACACAGAAATATCCCAAGCTTATTCAGGGACCTCTACAAGGA AAGGTAGTTGTTTGTGTGTCAGCTGGATACAGACATAGTGCTGCTGTCACAGAGGATGGGGAATTATACACATGGGGTGAAGGAGACTTT GGAAGATTAGGTCATGGTGACAGCAATAGTCGTAACATTCCAACATTAGTAAAAGACATCAGCAATGTAGGAGAGGTTTCTTGTGGCAGT TCACATACTATTGCTCTGTCTAAAGATGGGAGAACTGTATGGTCTTTTGGAGGAGGAGACAATGGTAAACTTGGTCATGGTGATACCAAC AGAGTGTATAAACCTAAAGTTATTGAAGCTTTACAAGGAATGTTCATTCGCAAAGTTTGTGCTGGGAGCCAGTCTTCACTTGCTTTGACA TCAACAGGGCAGGTCTATGCTTGGGGCTGTGGAGCTTGTCTAGGTTGTGGTTCTTCAGAAGCTACTGCTTTGAGACCCAAGCTTATTGAA GAACTGGCTGCCACAAGAATAGTTGATGTTTCTATTGGAGACAGTCATTGTTTGGCTCTTTCTCATGATAATGAAGTTTATGCCTGGGGC AATAACTCAATGGGGCAATGTGGTCAGGGAAATTCCACAGGTCCTATTACTAAACCAAAGAAAGTGAGTGGCTTAGATGGCATAGCTATT CAGCAGATTTCGGCTGGAACATCACATAGTCTGGCATGGACTGCTCTTCCTAGGGACAGACAAGTTGTTGCATGGCACCGACCTTATTGT GTAGATCTTGAAGAGAGTACCTTCTCACACCTGCGTTCTTTTCTTGAGAGATACTGTGATAAAATAAACAGTGAGATTCCCCCACTCCCT TTCCCTTCATCAAGAGAACACCACAGTTTTCTCAAGCTGTGCCTGAAGCTACTTTCAAATCACCTTGCTCTTGCACTTGCGGGAGGGGTA GCTACCAGCATTCTCGGGAGGCAGGCAGGTCCACTTCGAAATTTGCTCTTCAGACTGATGGACTCAACTGTCCCAGATGAAATCCAAGAG GTGGTAATTGAAACTTTATCAGTGGGAGCAACCATGCTGTTACCTCCATTACGAGAACGGATGGAATTACTTCATTCTCTTTTACCTCAA GGACCTGATAGATGGGAAAGCTTATCTAAAGGACAGAGAATGCAACTGGATATCATCCTGACAAGTTTGCAAGATCATACCCACGTAGCC TCCCTACTTGGCTATAGTTCACCCTCTGATGCTGCTGACCTATCTTCTGTGTGTACTGGCTACGGAAATCTGTCAGATCAACCTTACGGC ACTCAGAGCTGCCATCCAGATACCCACCTGGCTGAAATTTTGATGAAGACCCTCTTAAGAAATTTAGGATTTTATACAGATCAAGCATTT GGAGAGCTAGAAAAGAATAGTGATAAATTTCTACTTGGAACATCATCATCAGAAAACAGTCAGCCTGCTCATCTTCATGAACTGCTATGT TCACTACAGAAACAGCTGCTGGCATTTTGCCATATCAATAACATTAGTGAGAACTCAAGCAGTGTGGCATTGCTTCATAAACATCTTCAG CTTTTGTTGCCTCATGCCACAGATATTTATTCACGTTCTGCAAATTTGCTCAAAGAAAGTCCTTGGAATGGCAGTGTTGGAGAAAAATTA AGAGATGTGATATACGTCTCAGCTGCTGGCAGTATGCTCTGCCAGATTGTTAACTCCCTGCTGTTACTCCCTGTGTCAGTGGCTCGGCCT TTATTGAGTTACCTCCTCGACTTGTTGCCACCTCTTGATTGCCTTAATAGACTCCTGCCAGCTGCTGATCTTTTAGAAGACCAGGAGTTA CAGTGGCCTCTTCATGGAGGGCCAGAACTAATTGATCCTGCTGGTCTGCCATTACCTCAGCCAGCTCAGTCCTGGGTATGGCTTGTGGAT CTAGAAAGAACAATTGCTCTCCTTATTGGGCGGTGTCTTGGTGGCATGCTTCAGGGCTCCCCTGTGTCTCCAGAGGAACAGGACACTGCA TATTGGATGAAAACGCCACTGTTCAGTGACGGTGTAGAAATGGACACTCCTCAATTGGATAAATGTATGAGTTGCCTGTTAGAAGTAGCA CTTTCTGGAAATGAAGAACAGAAGCCTTTTGATTATAAATTGCGGCCTGAAATTGCTGTCTATGTAGACTTGGCATTGGGTTGTTCTAAA GAGCCTGCCCGAAGCCTTTGGATCAGCATGCAGGACTATGCTGTTAGTAAAGATTGGGACAGTGCAACTTTAAGTAATGAGTCACTCTTG GACACTGTGTCTAGATTTGTTCTTGCAGCTCTTCTGAAACACACAAATTTACTTAGTCAAGCATGTGGAGAAAGCCGATATCAACCTGGT AAACACTTATCAGAAGTGTACCGTTGTGTATACAAAGTTCGAAGTCGTTTACTTGCTTGCAAGAACCTTGAACTTATTCAAACAAGGTCA TCATCACGGGACAGATGGATATCAGAAAACCAGGACTCTGCAGATGTTGATCCTCAGGAGCATTCATTTACTCGAACTATTGATGAAGAA GCTGAAATGGAAGAACAGGCTGAGAGAGACCGGGAAGAGGGGCATCCGGAGCCAGAGGATGAAGAGGAGGAACGGGAACATGAAGTGATG ACAGCTGGCAAAATCTTTCAGTGTTTCCTCTCAGCCCGTGAAGTAGCTCGTAGCCGAGACCGAGATAGAATGAACAGTGGGGCAGGGTCT GGGGCTCGAGCTGATGATCCACCTCCTCAGTCTCAGCAAGAGCGAAGGGTCAGCACAGACCTTCCTGAGGGTCAGGATGTGTACACTGCT GCATGCAACTCCGTGATCCATCGGTGTGCCCTGTTAATATTAGGAGTAAGTCCTGTGATAGATGAGCTTCAGAAGCGAAGAGAAGAAGGA CAGTTGCAGCAACCTTCAACAAGTGCCTCTGAAGGGGGTGGACTTATGACCAGGAGTGAAAGTCTTACTGCAGAGAGCCGGCTAGTCCAC ACAAGCCCAAATTATAGACTGATCAAATCGAGGAGTGAATCTGATTTGTCTCAGCCTGAATCAGATGAAGAGGGTTACGCACTGAGTGGC AGACGAAATGTTGATTTGGATTTGGCAGCATCTCACAGAAAGAGAGGTCCTATGCACAGTCAATTGGAATCCCTGAGTGACTCTTGGGCT CGCCTGAAACATAGCAGAGACTGGTTATGCAACTCCTCCTATTCCTTTGAGTCAGATTTTGATCTTACCAAGTCTTTGGGAGTTCACACT TTGATTGAAAATGTTGTAAGCTTTGTGAGTGGAGATGTGGGGAATGCCCCAGGTTTTAAAGAGCCAGAGGAAAGTATGTCTACAAGTCCC CAGGCCTCCATCATTGCAATGGAACAGCAGCAGTTAAGGGCAGAACTTCGTTTAGAGGCACTTCATCAGATCCTCGTTCTATTGTCTGGG ATGGAAGAAAAAGGTAGCATCTCACTGGCAGGAAGCAGATTGAGTTCAGGCTTCCAGTCCTCCACACTACTCACGTCTGTGAGGCTGCAG TTCCTAGCAGGGTGTTTTGGTTTAGGCACTGTTGGACACACAGGAGGCAAGGGAGAGAGTGGCCGATTGCATCACTATCAGAGTGTCTGG AGGAGAGCTCTTCGATTTCCTGGCCCAGAAGGAGTCACTGAGTGAGGAGGAGGCCACCAGCTTCATTAAGCAGATCCTGGATGGGGTGAA CTACCTTCACACAAAGAAAATTGCTCACTTTGATCTCAAGCCAGAAAACATTATGTTGTTAGACAAGAATATTCCCATTCCACACATCAA GCTGATTGACTTTGGTCTGGCTCACGAAATAGAAGATGGAGTTGAATTTAAGAATATTTTTGGGACGCCGGAATTTGTTGCTCCAGAAAT TGTGAACTACGAGCCCCTGGGTCTGGAGGCTGACATGTGGAGCATAGGCGTCATCACCTACATCCTCTTAAGTGGAGCATCCCCTTTCCT GGGAGACACGAAGCAGGAAACACTGGCAAATATCACAGCAGTGAGTTACGACTTTGATGAGGAATTCTTCAGCCAGACGAGCGAGCTGGC CAAGGACTTTATTCGGAAGCTTCTGGTTAAAGAGACCCGGAAACGGCTCACAATCCAAGAGGCTCTCAGACACCCCTGGATCACGTCAAA AGGAGAAGGCAGAGCCCCTGAACAGCGGAAGACAGAGCCCACCCAGCTGAAGACCAAGCACCTGAGAGAGTACACTCTCAAATGCCACTC AAGCATGCCTCCCAACAACTCCTATGTCAACTTCGAGCGTTTTGCCTGTGTGGTGGAAGACGTGGCTCGGGTCGACCTGGGATGCCGTGC CCTGGTGGAGGCCCACGATACCATCCAGGACGATGTGGAGGCCCTGGTCTCCATCTTCAATGAGAAGGAAGCTTGGTACCGAGAGGAGAA TGAGAGCGCCCGGCATGACCTGTCCCAGCTCAGGTATGAGTTCCGCAAGGTGGAGTCATTGAAGAAGCTGCTGCGAGAAGACATCCAGGC CACGGGATGTAGCCTCGGAAGCATGGCCAGGAAACTGGACCATCTGCAAGCCCAGTTTGAGATTCTGAGGCAGGAGCTCTCCGCAGACCT GCAGTGGATTCAGGAGCTGGTGGGCAGCTTCCAGCTGGAGAGTGGGAGCTCTGAGGGCCTGGGCTCCACATTCTACCAGGACACCAGTGA |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_HERC1_ENST00000443617_chr15_63988323_-_DAPK2_ENST00000261891_chr15_64263760_-_7492nt CCTCTGCGGAGCCGGGCTCGGGTCGCCGGAGCCGCGCCCCACCCCGCCAGCTCCAGAGCCACGACTAATGGCTGAAGGATAAATCAACAT GGCAACTATGATTCCACCAGTGAAGCTGAAATGGCTTGAACACTTGAACAGCTCCTGGATTACAGAGGACAGTGAATCTATTGCTACAAG AGAGGGAGTTGCTGTTCTGTATTCTAAACTGGTTAGCAATAAGGAAGTAGTACCTTTGCCCCAACAAGTTTTATGCCTCAAAGGACCACA GTTGCCAGACTTTGAACGTGAGTCTCTTTCAAGTGATGAGCAGGACCACTATTTGGATGCCCTTCTTAGCAGCCAGCTAGCATTGGCAAA GATGGTATGTTCAGATTCCCCATTTGCCGGGGCACTTAGAAAACGACTGCTTGTACTCCAGCGTGTCTTTTATGCACTTTCTAATAAATA CCATGACAAAGGCAAGGTGAAGCAGCAGCAGCATTCTCCGGAGAGCAGTTCTGGTTCAGCAGATGTCCATTCTGTTAGTGAACGCCCCCG GTCAAGCACTGATGCACTTATAGAAATGGGTGTTCGAACTGGTCTAAGTTTATTATTTGCGCTTCTAAGACAAAGTTGGATGATGCCTGT GTCAGGACCTGGTCTCAGTCTTTGCAACGATGTCATTCATACTGCAATTGAAGTTGTGAGCTCTTTGCCACCATTATCATTAGCAAATGA AAGCAAGATTCCTCCTATGGGCTTGGACTGCTTATCGCAAGTAACAACATTTCTTAAAGGAGTCACTATTCCTAATTCTGGGGCAGACAC TTTAGGTCGTAGATTAGCTTCTGAGTTGCTGCTTGGTTTGGCAGCTCAACGAGGCTCATTGCGATATCTTCTTGAATGGATAGAAATGGC TTTGGGGGCTTCGGCAGTTGTACACACCATGGAGAAAGGCAAACTACTCTCAAGCCAGGAAGGAATGATCAGCTTTGACTGCTTTATGAC CATATTAATGCAGATGAGGCGTTCTTTGGGTTCATCTGCTGATCGGAGTCAGTGGAGAGAACCAACCAGAACATCGGATGGCTTGTGCTC CCTTTACGAGGCAGCATTATGTCTCTTTGAAGAGGTTTGCAGAATGGCTTCTGATTATTCGAGAACATGTGCTAGCCCAGATAGCATTCA GACTGGTGATGCTCCCATTGTCTCCGAAACCTGTGAGGTTTATGTTTGGGGGAGCAATAGCAGCCATCAGTTGGTAGAAGGTACACAGGA GAAAATACTGCAACCCAAACTGGCTCCTAGTTTCTCTGATGCACAGACCATTGAAGCTGGACAGTACTGCACTTTTGTCATTTCTACGGA TGGCTCTGTTAGAGCTTGCGGGAAAGGCAGCTATGGGAGACTGGGCCTTGGAGACTCCAATAATCAGTCAACTTTAAAAAAGTTAACATT CGAGCCTCACAGATCCATTAAAAAGGTTTCATCTTCTAAAGGATCTGATGGTCACACTTTAGCCTTTACGACAGAAGGAGAAGTCTTCAG TTGGGGAGATGGTGATTATGGGAAACTGGGGCATGGAAATAGTTCAACACAGAAATATCCCAAGCTTATTCAGGGACCTCTACAAGGAAA GGTAGTTGTTTGTGTGTCAGCTGGATACAGACATAGTGCTGCTGTCACAGAGGATGGGGAATTATACACATGGGGTGAAGGAGACTTTGG AAGATTAGGTCATGGTGACAGCAATAGTCGTAACATTCCAACATTAGTAAAAGACATCAGCAATGTAGGAGAGGTTTCTTGTGGCAGTTC ACATACTATTGCTCTGTCTAAAGATGGGAGAACTGTATGGTCTTTTGGAGGAGGAGACAATGGTAAACTTGGTCATGGTGATACCAACAG AGTGTATAAACCTAAAGTTATTGAAGCTTTACAAGGAATGTTCATTCGCAAAGTTTGTGCTGGGAGCCAGTCTTCACTTGCTTTGACATC AACAGGGCAGGTCTATGCTTGGGGCTGTGGAGCTTGTCTAGGTTGTGGTTCTTCAGAAGCTACTGCTTTGAGACCCAAGCTTATTGAAGA ACTGGCTGCCACAAGAATAGTTGATGTTTCTATTGGAGACAGTCATTGTTTGGCTCTTTCTCATGATAATGAAGTTTATGCCTGGGGCAA TAACTCAATGGGGCAATGTGGTCAGGGAAATTCCACAGGTCCTATTACTAAACCAAAGAAAGTGAGTGGCTTAGATGGCATAGCTATTCA GCAGATTTCGGCTGGAACATCACATAGTCTGGCATGGACTGCTCTTCCTAGGGACAGACAAGTTGTTGCATGGCACCGACCTTATTGTGT AGATCTTGAAGAGAGTACCTTCTCACACCTGCGTTCTTTTCTTGAGAGATACTGTGATAAAATAAACAGTGAGATTCCCCCACTCCCTTT CCCTTCATCAAGAGAACACCACAGTTTTCTCAAGCTGTGCCTGAAGCTACTTTCAAATCACCTTGCTCTTGCACTTGCGGGAGGGGTAGC TACCAGCATTCTCGGGAGGCAGGCAGGTCCACTTCGAAATTTGCTCTTCAGACTGATGGACTCAACTGTCCCAGATGAAATCCAAGAGGT GGTAATTGAAACTTTATCAGTGGGAGCAACCATGCTGTTACCTCCATTACGAGAACGGATGGAATTACTTCATTCTCTTTTACCTCAAGG ACCTGATAGATGGGAAAGCTTATCTAAAGGACAGAGAATGCAACTGGATATCATCCTGACAAGTTTGCAAGATCATACCCACGTAGCCTC CCTACTTGGCTATAGTTCACCCTCTGATGCTGCTGACCTATCTTCTGTGTGTACTGGCTACGGAAATCTGTCAGATCAACCTTACGGCAC TCAGAGCTGCCATCCAGATACCCACCTGGCTGAAATTTTGATGAAGACCCTCTTAAGAAATTTAGGATTTTATACAGATCAAGCATTTGG AGAGCTAGAAAAGAATAGTGATAAATTTCTACTTGGAACATCATCATCAGAAAACAGTCAGCCTGCTCATCTTCATGAACTGCTATGTTC ACTACAGAAACAGCTGCTGGCATTTTGCCATATCAATAACATTAGTGAGAACTCAAGCAGTGTGGCATTGCTTCATAAACATCTTCAGCT TTTGTTGCCTCATGCCACAGATATTTATTCACGTTCTGCAAATTTGCTCAAAGAAAGTCCTTGGAATGGCAGTGTTGGAGAAAAATTAAG AGATGTGATATACGTCTCAGCTGCTGGCAGTATGCTCTGCCAGATTGTTAACTCCCTGCTGTTACTCCCTGTGTCAGTGGCTCGGCCTTT ATTGAGTTACCTCCTCGACTTGTTGCCACCTCTTGATTGCCTTAATAGACTCCTGCCAGCTGCTGATCTTTTAGAAGACCAGGAGTTACA GTGGCCTCTTCATGGAGGGCCAGAACTAATTGATCCTGCTGGTCTGCCATTACCTCAGCCAGCTCAGTCCTGGGTATGGCTTGTGGATCT AGAAAGAACAATTGCTCTCCTTATTGGGCGGTGTCTTGGTGGCATGCTTCAGGGCTCCCCTGTGTCTCCAGAGGAACAGGACACTGCATA TTGGATGAAAACGCCACTGTTCAGTGACGGTGTAGAAATGGACACTCCTCAATTGGATAAATGTATGAGTTGCCTGTTAGAAGTAGCACT TTCTGGAAATGAAGAACAGAAGCCTTTTGATTATAAATTGCGGCCTGAAATTGCTGTCTATGTAGACTTGGCATTGGGTTGTTCTAAAGA GCCTGCCCGAAGCCTTTGGATCAGCATGCAGGACTATGCTGTTAGTAAAGATTGGGACAGTGCAACTTTAAGTAATGAGTCACTCTTGGA CACTGTGTCTAGATTTGTTCTTGCAGCTCTTCTGAAACACACAAATTTACTTAGTCAAGCATGTGGAGAAAGCCGATATCAACCTGGTAA ACACTTATCAGAAGTGTACCGTTGTGTATACAAAGTTCGAAGTCGTTTACTTGCTTGCAAGAACCTTGAACTTATTCAAACAAGGTCATC ATCACGGGACAGATGGATATCAGAAAACCAGGACTCTGCAGATGTTGATCCTCAGGAGCATTCATTTACTCGAACTATTGATGAAGAAGC TGAAATGGAAGAACAGGCTGAGAGAGACCGGGAAGAGGGGCATCCGGAGCCAGAGGATGAAGAGGAGGAACGGGAACATGAAGTGATGAC AGCTGGCAAAATCTTTCAGTGTTTCCTCTCAGCCCGTGAAGTAGCTCGTAGCCGAGACCGAGATAGAATGAACAGTGGGGCAGGGTCTGG GGCTCGAGCTGATGATCCACCTCCTCAGTCTCAGCAAGAGCGAAGGGTCAGCACAGACCTTCCTGAGGGTCAGGATGTGTACACTGCTGC ATGCAACTCCGTGATCCATCGGTGTGCCCTGTTAATATTAGGAGTAAGTCCTGTGATAGATGAGCTTCAGAAGCGAAGAGAAGAAGGACA GTTGCAGCAACCTTCAACAAGTGCCTCTGAAGGGGGTGGACTTATGACCAGGAGTGAAAGTCTTACTGCAGAGAGCCGGCTAGTCCACAC AAGCCCAAATTATAGACTGATCAAATCGAGGAGTGAATCTGATTTGTCTCAGCCTGAATCAGATGAAGAGGGTTACGCACTGAGTGGCAG ACGAAATGTTGATTTGGATTTGGCAGCATCTCACAGAAAGAGAGGTCCTATGCACAGTCAATTGGAATCCCTGAGTGACTCTTGGGCTCG CCTGAAACATAGCAGAGACTGGTTATGCAACTCCTCCTATTCCTTTGAGTCAGATTTTGATCTTACCAAGTCTTTGGGAGTTCACACTTT GATTGAAAATGTTGTAAGCTTTGTGAGTGGAGATGTGGGGAATGCCCCAGGTTTTAAAGAGCCAGAGGAAAGTATGTCTACAAGTCCCCA GGCCTCCATCATTGCAATGGAACAGCAGCAGTTAAGGGCAGAACTTCGTTTAGAGGCACTTCATCAGATCCTCGTTCTATTGTCTGGGAT GGAAGAAAAAGGTAGCATCTCACTGGCAGGAAGCAGATTGAGTTCAGGCTTCCAGTCCTCCACACTACTCACGTCTGTGAGGCTGCAGTT CCTAGCAGGGTGTTTTGGTTTAGGCACTGTTGGACACACAGGAGGCAAGGGAGAGAGTGGCCGATTGCATCACTATCAGAGTGTCTGGAG GAGAGCTCTTCGATTTCCTGGCCCAGAAGGAGTCACTGAGTGAGGAGGAGGCCACCAGCTTCATTAAGCAGATCCTGGATGGGGTGAACT ACCTTCACACAAAGAAAATTGCTCACTTTGATCTCAAGCCAGAAAACATTATGTTGTTAGACAAGAATATTCCCATTCCACACATCAAGC TGATTGACTTTGGTCTGGCTCACGAAATAGAAGATGGAGTTGAATTTAAGAATATTTTTGGGACGCCGGAATTTGTTGCTCCAGAAATTG TGAACTACGAGCCCCTGGGTCTGGAGGCTGACATGTGGAGCATAGGCGTCATCACCTACATCCTCTTAAGTGGAGCATCCCCTTTCCTGG GAGACACGAAGCAGGAAACACTGGCAAATATCACAGCAGTGAGTTACGACTTTGATGAGGAATTCTTCAGCCAGACGAGCGAGCTGGCCA AGGACTTTATTCGGAAGCTTCTGGTTAAAGAGACCCGGAAACGGCTCACAATCCAAGAGGCTCTCAGACACCCCTGGATCACGCCGGTGG ACAACCAGCAAGCCATGGTGCGCAGGGAGTCTGTGGTCAATCTGGAGAACTTCAGGAAGCAGTATGTCCGCAGGCGGTGGAAGCTTTCCT TCAGCATCGTGTCCCTGTGCAACCACCTCACCCGCTCGCTGATGAAGAAGGTGCACCTGAGGCCGGATGAGGACCTGAGGAACTGTGAGA GTGACACTGAGGAGGACATCGCCAGGAGGAAAGCCCTCCACCCACGGAGGAGGAGCAGCACCTCCTAACTGGCCTGACCTGCAGTGGCCG CCAGGGAGGTCTGGGCCCAGCGGGGCTCCCTTCTGTGCAGACTTTTGGACCCAGCTCAGCACCAGCACCCGGGCGTCCTGAGCACTTTGC AAGAGAGATGGGCCCAAGGAATTCAGAAGAGCTTGCAGGCAAGCCAGGAGACCCTGGGAGCTGTGGCTGTCTTCTGTGGAGGAGGCTCCA GCATTCCCAAAGCTCTTAATTCTCCATAAAATGGGCTTTCCTCTGTCTGCCATCCTCAGAGTCTGGGGTGGGAGTGTGGACTTAGGAAAA CAATATAAAGGACATCCTCATCATCACGGGGTGAAGGTCAGACTAAGGCAGCCTTCTTCACAGGCTGAGGGGGTTCAGAACCAGCCTGGC CAAAAATTACACCAGAGAGACAGAGTCCTCCCCATTGGGAACAGGGTGATTGAGGAAAGTGAACCTTGGGTGTGAGGGACCAATCCTGTG ACCTCCCAGAACCATGGAAGCCAGGACGTCAGGCTGACCAACACCTCAGACCTTCTGAAGCAGCCCATTGCTGGCCCGCCATGTTGTAAT TTTGCTCATTTTTATTAAACTTCTGGTTTACCTGATGCTTGGCTTCTTTTAGGGCTACCCCCATCTCATTTCCTTTAGCCCGTGTGCCTG TAACTCTGAGGGGGGGCACCCAGTGGGGTGCTGAGTGGGCAGAATCTCAGAAGGTCCTCCTGAACCGTCCGCGCAGGCCTGCAGTGGGCC TGCCTCCTCCTTGCTTCCCTAACAGGAAGGTGTCCAGTTCAAGAGAACCCACCCAGAGACTGGGAGTGGTGGCTCACGCCTATAATCCCT GCGCTTTGGCAGTCCGAGGCAGGGGAATTGCTTGAACTCAGGAGTTGGAGACCAGCCTGGGCAACATGGCAAAACGCAGTCTGTACAAAA AATACAAAAAATTAGCCAGGTGTAGGGGTAGGCACCTGGCATCCCAGCTACTCCAGGGGCTGAGGTGACAGCATTGCTTAAGCCCAGAAG GTCGAGGCTGCAGTGAGCTGAGATCACGCCACTGCACTCCAGTCTGGGTGACAGAGAGAGACCATATCCAAAAAAAAAAAAAGTTGCCAG AGACGAGTATGCCCATGCTCCCTCTACCTCACTGCCACCACTCCTGCTGTTAGGAGCTGAGTGTGTCTCCCTAAAATTTCTATGTTGAAG TCTTAACCCTTGGTACCACAGAATATCACTGTATTTGGAGATGGGGTCTTTAGAAAGGCACTTAAATTAAAATGAGCTCACTGATATGGG CCCCGATGCAATATAATTGGTGTCCTTATAAGAAGGGGAGGTTAGGACACGCAGGAAAGACCACATGAAGGCCCAGGAGTGGGAGGGGGA ATAGCCATCGACAAACTAAGGGGGCCTCAGAGGAAACCAACCCTGCTGACACCTCAATCTTAGACTCTGGCCTCAAAAATTGTAAGAAAA >In-frame_HERC1_ENST00000443617_chr15_63988323_-_DAPK2_ENST00000457488_chr15_64263760_-_6605nt CCTCTGCGGAGCCGGGCTCGGGTCGCCGGAGCCGCGCCCCACCCCGCCAGCTCCAGAGCCACGACTAATGGCTGAAGGATAAATCAACAT GGCAACTATGATTCCACCAGTGAAGCTGAAATGGCTTGAACACTTGAACAGCTCCTGGATTACAGAGGACAGTGAATCTATTGCTACAAG AGAGGGAGTTGCTGTTCTGTATTCTAAACTGGTTAGCAATAAGGAAGTAGTACCTTTGCCCCAACAAGTTTTATGCCTCAAAGGACCACA GTTGCCAGACTTTGAACGTGAGTCTCTTTCAAGTGATGAGCAGGACCACTATTTGGATGCCCTTCTTAGCAGCCAGCTAGCATTGGCAAA GATGGTATGTTCAGATTCCCCATTTGCCGGGGCACTTAGAAAACGACTGCTTGTACTCCAGCGTGTCTTTTATGCACTTTCTAATAAATA CCATGACAAAGGCAAGGTGAAGCAGCAGCAGCATTCTCCGGAGAGCAGTTCTGGTTCAGCAGATGTCCATTCTGTTAGTGAACGCCCCCG GTCAAGCACTGATGCACTTATAGAAATGGGTGTTCGAACTGGTCTAAGTTTATTATTTGCGCTTCTAAGACAAAGTTGGATGATGCCTGT GTCAGGACCTGGTCTCAGTCTTTGCAACGATGTCATTCATACTGCAATTGAAGTTGTGAGCTCTTTGCCACCATTATCATTAGCAAATGA AAGCAAGATTCCTCCTATGGGCTTGGACTGCTTATCGCAAGTAACAACATTTCTTAAAGGAGTCACTATTCCTAATTCTGGGGCAGACAC TTTAGGTCGTAGATTAGCTTCTGAGTTGCTGCTTGGTTTGGCAGCTCAACGAGGCTCATTGCGATATCTTCTTGAATGGATAGAAATGGC TTTGGGGGCTTCGGCAGTTGTACACACCATGGAGAAAGGCAAACTACTCTCAAGCCAGGAAGGAATGATCAGCTTTGACTGCTTTATGAC CATATTAATGCAGATGAGGCGTTCTTTGGGTTCATCTGCTGATCGGAGTCAGTGGAGAGAACCAACCAGAACATCGGATGGCTTGTGCTC CCTTTACGAGGCAGCATTATGTCTCTTTGAAGAGGTTTGCAGAATGGCTTCTGATTATTCGAGAACATGTGCTAGCCCAGATAGCATTCA GACTGGTGATGCTCCCATTGTCTCCGAAACCTGTGAGGTTTATGTTTGGGGGAGCAATAGCAGCCATCAGTTGGTAGAAGGTACACAGGA GAAAATACTGCAACCCAAACTGGCTCCTAGTTTCTCTGATGCACAGACCATTGAAGCTGGACAGTACTGCACTTTTGTCATTTCTACGGA TGGCTCTGTTAGAGCTTGCGGGAAAGGCAGCTATGGGAGACTGGGCCTTGGAGACTCCAATAATCAGTCAACTTTAAAAAAGTTAACATT CGAGCCTCACAGATCCATTAAAAAGGTTTCATCTTCTAAAGGATCTGATGGTCACACTTTAGCCTTTACGACAGAAGGAGAAGTCTTCAG TTGGGGAGATGGTGATTATGGGAAACTGGGGCATGGAAATAGTTCAACACAGAAATATCCCAAGCTTATTCAGGGACCTCTACAAGGAAA GGTAGTTGTTTGTGTGTCAGCTGGATACAGACATAGTGCTGCTGTCACAGAGGATGGGGAATTATACACATGGGGTGAAGGAGACTTTGG AAGATTAGGTCATGGTGACAGCAATAGTCGTAACATTCCAACATTAGTAAAAGACATCAGCAATGTAGGAGAGGTTTCTTGTGGCAGTTC ACATACTATTGCTCTGTCTAAAGATGGGAGAACTGTATGGTCTTTTGGAGGAGGAGACAATGGTAAACTTGGTCATGGTGATACCAACAG AGTGTATAAACCTAAAGTTATTGAAGCTTTACAAGGAATGTTCATTCGCAAAGTTTGTGCTGGGAGCCAGTCTTCACTTGCTTTGACATC AACAGGGCAGGTCTATGCTTGGGGCTGTGGAGCTTGTCTAGGTTGTGGTTCTTCAGAAGCTACTGCTTTGAGACCCAAGCTTATTGAAGA ACTGGCTGCCACAAGAATAGTTGATGTTTCTATTGGAGACAGTCATTGTTTGGCTCTTTCTCATGATAATGAAGTTTATGCCTGGGGCAA TAACTCAATGGGGCAATGTGGTCAGGGAAATTCCACAGGTCCTATTACTAAACCAAAGAAAGTGAGTGGCTTAGATGGCATAGCTATTCA GCAGATTTCGGCTGGAACATCACATAGTCTGGCATGGACTGCTCTTCCTAGGGACAGACAAGTTGTTGCATGGCACCGACCTTATTGTGT AGATCTTGAAGAGAGTACCTTCTCACACCTGCGTTCTTTTCTTGAGAGATACTGTGATAAAATAAACAGTGAGATTCCCCCACTCCCTTT CCCTTCATCAAGAGAACACCACAGTTTTCTCAAGCTGTGCCTGAAGCTACTTTCAAATCACCTTGCTCTTGCACTTGCGGGAGGGGTAGC TACCAGCATTCTCGGGAGGCAGGCAGGTCCACTTCGAAATTTGCTCTTCAGACTGATGGACTCAACTGTCCCAGATGAAATCCAAGAGGT GGTAATTGAAACTTTATCAGTGGGAGCAACCATGCTGTTACCTCCATTACGAGAACGGATGGAATTACTTCATTCTCTTTTACCTCAAGG ACCTGATAGATGGGAAAGCTTATCTAAAGGACAGAGAATGCAACTGGATATCATCCTGACAAGTTTGCAAGATCATACCCACGTAGCCTC CCTACTTGGCTATAGTTCACCCTCTGATGCTGCTGACCTATCTTCTGTGTGTACTGGCTACGGAAATCTGTCAGATCAACCTTACGGCAC TCAGAGCTGCCATCCAGATACCCACCTGGCTGAAATTTTGATGAAGACCCTCTTAAGAAATTTAGGATTTTATACAGATCAAGCATTTGG AGAGCTAGAAAAGAATAGTGATAAATTTCTACTTGGAACATCATCATCAGAAAACAGTCAGCCTGCTCATCTTCATGAACTGCTATGTTC ACTACAGAAACAGCTGCTGGCATTTTGCCATATCAATAACATTAGTGAGAACTCAAGCAGTGTGGCATTGCTTCATAAACATCTTCAGCT TTTGTTGCCTCATGCCACAGATATTTATTCACGTTCTGCAAATTTGCTCAAAGAAAGTCCTTGGAATGGCAGTGTTGGAGAAAAATTAAG AGATGTGATATACGTCTCAGCTGCTGGCAGTATGCTCTGCCAGATTGTTAACTCCCTGCTGTTACTCCCTGTGTCAGTGGCTCGGCCTTT ATTGAGTTACCTCCTCGACTTGTTGCCACCTCTTGATTGCCTTAATAGACTCCTGCCAGCTGCTGATCTTTTAGAAGACCAGGAGTTACA GTGGCCTCTTCATGGAGGGCCAGAACTAATTGATCCTGCTGGTCTGCCATTACCTCAGCCAGCTCAGTCCTGGGTATGGCTTGTGGATCT AGAAAGAACAATTGCTCTCCTTATTGGGCGGTGTCTTGGTGGCATGCTTCAGGGCTCCCCTGTGTCTCCAGAGGAACAGGACACTGCATA TTGGATGAAAACGCCACTGTTCAGTGACGGTGTAGAAATGGACACTCCTCAATTGGATAAATGTATGAGTTGCCTGTTAGAAGTAGCACT TTCTGGAAATGAAGAACAGAAGCCTTTTGATTATAAATTGCGGCCTGAAATTGCTGTCTATGTAGACTTGGCATTGGGTTGTTCTAAAGA GCCTGCCCGAAGCCTTTGGATCAGCATGCAGGACTATGCTGTTAGTAAAGATTGGGACAGTGCAACTTTAAGTAATGAGTCACTCTTGGA CACTGTGTCTAGATTTGTTCTTGCAGCTCTTCTGAAACACACAAATTTACTTAGTCAAGCATGTGGAGAAAGCCGATATCAACCTGGTAA ACACTTATCAGAAGTGTACCGTTGTGTATACAAAGTTCGAAGTCGTTTACTTGCTTGCAAGAACCTTGAACTTATTCAAACAAGGTCATC ATCACGGGACAGATGGATATCAGAAAACCAGGACTCTGCAGATGTTGATCCTCAGGAGCATTCATTTACTCGAACTATTGATGAAGAAGC TGAAATGGAAGAACAGGCTGAGAGAGACCGGGAAGAGGGGCATCCGGAGCCAGAGGATGAAGAGGAGGAACGGGAACATGAAGTGATGAC AGCTGGCAAAATCTTTCAGTGTTTCCTCTCAGCCCGTGAAGTAGCTCGTAGCCGAGACCGAGATAGAATGAACAGTGGGGCAGGGTCTGG GGCTCGAGCTGATGATCCACCTCCTCAGTCTCAGCAAGAGCGAAGGGTCAGCACAGACCTTCCTGAGGGTCAGGATGTGTACACTGCTGC ATGCAACTCCGTGATCCATCGGTGTGCCCTGTTAATATTAGGAGTAAGTCCTGTGATAGATGAGCTTCAGAAGCGAAGAGAAGAAGGACA GTTGCAGCAACCTTCAACAAGTGCCTCTGAAGGGGGTGGACTTATGACCAGGAGTGAAAGTCTTACTGCAGAGAGCCGGCTAGTCCACAC AAGCCCAAATTATAGACTGATCAAATCGAGGAGTGAATCTGATTTGTCTCAGCCTGAATCAGATGAAGAGGGTTACGCACTGAGTGGCAG ACGAAATGTTGATTTGGATTTGGCAGCATCTCACAGAAAGAGAGGTCCTATGCACAGTCAATTGGAATCCCTGAGTGACTCTTGGGCTCG CCTGAAACATAGCAGAGACTGGTTATGCAACTCCTCCTATTCCTTTGAGTCAGATTTTGATCTTACCAAGTCTTTGGGAGTTCACACTTT GATTGAAAATGTTGTAAGCTTTGTGAGTGGAGATGTGGGGAATGCCCCAGGTTTTAAAGAGCCAGAGGAAAGTATGTCTACAAGTCCCCA GGCCTCCATCATTGCAATGGAACAGCAGCAGTTAAGGGCAGAACTTCGTTTAGAGGCACTTCATCAGATCCTCGTTCTATTGTCTGGGAT GGAAGAAAAAGGTAGCATCTCACTGGCAGGAAGCAGATTGAGTTCAGGCTTCCAGTCCTCCACACTACTCACGTCTGTGAGGCTGCAGTT CCTAGCAGGGTGTTTTGGTTTAGGCACTGTTGGACACACAGGAGGCAAGGGAGAGAGTGGCCGATTGCATCACTATCAGAGTGTCTGGAG GAGAGCTCTTCGATTTCCTGGCCCAGAAGGAGTCACTGAGTGAGGAGGAGGCCACCAGCTTCATTAAGCAGATCCTGGATGGGGTGAACT ACCTTCACACAAAGAAAATTGCTCACTTTGATCTCAAGCCAGAAAACATTATGTTGTTAGACAAGAATATTCCCATTCCACACATCAAGC TGATTGACTTTGGTCTGGCTCACGAAATAGAAGATGGAGTTGAATTTAAGAATATTTTTGGGACGCCGGAATTTGTTGCTCCAGAAATTG TGAACTACGAGCCCCTGGGTCTGGAGGCTGACATGTGGAGCATAGGCGTCATCACCTACATCCTCTTAAGTGGAGCATCCCCTTTCCTGG GAGACACGAAGCAGGAAACACTGGCAAATATCACAGCAGTGAGTTACGACTTTGATGAGGAATTCTTCAGCCAGACGAGCGAGCTGGCCA AGGACTTTATTCGGAAGCTTCTGGTTAAAGAGACCCGGAAACGGCTCACAATCCAAGAGGCTCTCAGACACCCCTGGATCACGCCGGTGG ACAACCAGCAAGCCATGGTGCGCAGGGAGTCTGTGGTCAATCTGGAGAACTTCAGGAAGCAGTATGTCCGCAGGCGGTGGAAGCTTTCCT TCAGCATCGTGTCCCTGTGCAACCACCTCACCCGCTCGCTGATGAAGAAGGTGCACCTGAGGCCGGATGAGGACCTGAGGAACTGTGAGA GTGACACTGAGGAGGACATCGCCAGGAGGAAAGCCCTCCACCCACGGAGGAGGAGCAGCACCTCCTAACTGGCCTGACCTGCAGTGGCCG CCAGGGAGGTCTGGGCCCAGCGGGGCTCCCTTCTGTGCAGACTTTTGGACCCAGCTCAGCACCAGCACCCGGGCGTCCTGAGCACTTTGC AAGAGAGATGGGCCCAAGGAATTCAGAAGAGCTTGCAGGCAAGCCAGGAGACCCTGGGAGCTGTGGCTGTCTTCTGTGGAGGAGGCTCCA GCATTCCCAAAGCTCTTAATTCTCCATAAAATGGGCTTTCCTCTGTCTGCCATCCTCAGAGTCTGGGGTGGGAGTGTGGACTTAGGAAAA CAATATAAAGGACATCCTCATCATCACGGGGTGAAGGTCAGACTAAGGCAGCCTTCTTCACAGGCTGAGGGGGTTCAGAACCAGCCTGGC CAAAAATTACACCAGAGAGACAGAGTCCTCCCCATTGGGAACAGGGTGATTGAGGAAAGTGAACCTTGGGTGTGAGGGACCAATCCTGTG ACCTCCCAGAACCATGGAAGCCAGGACGTCAGGCTGACCAACACCTCAGACCTTCTGAAGCAGCCCATTGCTGGCCCGCCATGTTGTAAT >In-frame_HERC1_ENST00000443617_chr15_63988323_-_DAPK2_ENST00000558069_chr15_64263760_-_6362nt CCTCTGCGGAGCCGGGCTCGGGTCGCCGGAGCCGCGCCCCACCCCGCCAGCTCCAGAGCCACGACTAATGGCTGAAGGATAAATCAACAT GGCAACTATGATTCCACCAGTGAAGCTGAAATGGCTTGAACACTTGAACAGCTCCTGGATTACAGAGGACAGTGAATCTATTGCTACAAG AGAGGGAGTTGCTGTTCTGTATTCTAAACTGGTTAGCAATAAGGAAGTAGTACCTTTGCCCCAACAAGTTTTATGCCTCAAAGGACCACA GTTGCCAGACTTTGAACGTGAGTCTCTTTCAAGTGATGAGCAGGACCACTATTTGGATGCCCTTCTTAGCAGCCAGCTAGCATTGGCAAA GATGGTATGTTCAGATTCCCCATTTGCCGGGGCACTTAGAAAACGACTGCTTGTACTCCAGCGTGTCTTTTATGCACTTTCTAATAAATA CCATGACAAAGGCAAGGTGAAGCAGCAGCAGCATTCTCCGGAGAGCAGTTCTGGTTCAGCAGATGTCCATTCTGTTAGTGAACGCCCCCG GTCAAGCACTGATGCACTTATAGAAATGGGTGTTCGAACTGGTCTAAGTTTATTATTTGCGCTTCTAAGACAAAGTTGGATGATGCCTGT GTCAGGACCTGGTCTCAGTCTTTGCAACGATGTCATTCATACTGCAATTGAAGTTGTGAGCTCTTTGCCACCATTATCATTAGCAAATGA AAGCAAGATTCCTCCTATGGGCTTGGACTGCTTATCGCAAGTAACAACATTTCTTAAAGGAGTCACTATTCCTAATTCTGGGGCAGACAC TTTAGGTCGTAGATTAGCTTCTGAGTTGCTGCTTGGTTTGGCAGCTCAACGAGGCTCATTGCGATATCTTCTTGAATGGATAGAAATGGC TTTGGGGGCTTCGGCAGTTGTACACACCATGGAGAAAGGCAAACTACTCTCAAGCCAGGAAGGAATGATCAGCTTTGACTGCTTTATGAC CATATTAATGCAGATGAGGCGTTCTTTGGGTTCATCTGCTGATCGGAGTCAGTGGAGAGAACCAACCAGAACATCGGATGGCTTGTGCTC CCTTTACGAGGCAGCATTATGTCTCTTTGAAGAGGTTTGCAGAATGGCTTCTGATTATTCGAGAACATGTGCTAGCCCAGATAGCATTCA GACTGGTGATGCTCCCATTGTCTCCGAAACCTGTGAGGTTTATGTTTGGGGGAGCAATAGCAGCCATCAGTTGGTAGAAGGTACACAGGA GAAAATACTGCAACCCAAACTGGCTCCTAGTTTCTCTGATGCACAGACCATTGAAGCTGGACAGTACTGCACTTTTGTCATTTCTACGGA TGGCTCTGTTAGAGCTTGCGGGAAAGGCAGCTATGGGAGACTGGGCCTTGGAGACTCCAATAATCAGTCAACTTTAAAAAAGTTAACATT CGAGCCTCACAGATCCATTAAAAAGGTTTCATCTTCTAAAGGATCTGATGGTCACACTTTAGCCTTTACGACAGAAGGAGAAGTCTTCAG TTGGGGAGATGGTGATTATGGGAAACTGGGGCATGGAAATAGTTCAACACAGAAATATCCCAAGCTTATTCAGGGACCTCTACAAGGAAA GGTAGTTGTTTGTGTGTCAGCTGGATACAGACATAGTGCTGCTGTCACAGAGGATGGGGAATTATACACATGGGGTGAAGGAGACTTTGG AAGATTAGGTCATGGTGACAGCAATAGTCGTAACATTCCAACATTAGTAAAAGACATCAGCAATGTAGGAGAGGTTTCTTGTGGCAGTTC ACATACTATTGCTCTGTCTAAAGATGGGAGAACTGTATGGTCTTTTGGAGGAGGAGACAATGGTAAACTTGGTCATGGTGATACCAACAG AGTGTATAAACCTAAAGTTATTGAAGCTTTACAAGGAATGTTCATTCGCAAAGTTTGTGCTGGGAGCCAGTCTTCACTTGCTTTGACATC AACAGGGCAGGTCTATGCTTGGGGCTGTGGAGCTTGTCTAGGTTGTGGTTCTTCAGAAGCTACTGCTTTGAGACCCAAGCTTATTGAAGA ACTGGCTGCCACAAGAATAGTTGATGTTTCTATTGGAGACAGTCATTGTTTGGCTCTTTCTCATGATAATGAAGTTTATGCCTGGGGCAA TAACTCAATGGGGCAATGTGGTCAGGGAAATTCCACAGGTCCTATTACTAAACCAAAGAAAGTGAGTGGCTTAGATGGCATAGCTATTCA GCAGATTTCGGCTGGAACATCACATAGTCTGGCATGGACTGCTCTTCCTAGGGACAGACAAGTTGTTGCATGGCACCGACCTTATTGTGT AGATCTTGAAGAGAGTACCTTCTCACACCTGCGTTCTTTTCTTGAGAGATACTGTGATAAAATAAACAGTGAGATTCCCCCACTCCCTTT CCCTTCATCAAGAGAACACCACAGTTTTCTCAAGCTGTGCCTGAAGCTACTTTCAAATCACCTTGCTCTTGCACTTGCGGGAGGGGTAGC TACCAGCATTCTCGGGAGGCAGGCAGGTCCACTTCGAAATTTGCTCTTCAGACTGATGGACTCAACTGTCCCAGATGAAATCCAAGAGGT GGTAATTGAAACTTTATCAGTGGGAGCAACCATGCTGTTACCTCCATTACGAGAACGGATGGAATTACTTCATTCTCTTTTACCTCAAGG ACCTGATAGATGGGAAAGCTTATCTAAAGGACAGAGAATGCAACTGGATATCATCCTGACAAGTTTGCAAGATCATACCCACGTAGCCTC CCTACTTGGCTATAGTTCACCCTCTGATGCTGCTGACCTATCTTCTGTGTGTACTGGCTACGGAAATCTGTCAGATCAACCTTACGGCAC TCAGAGCTGCCATCCAGATACCCACCTGGCTGAAATTTTGATGAAGACCCTCTTAAGAAATTTAGGATTTTATACAGATCAAGCATTTGG AGAGCTAGAAAAGAATAGTGATAAATTTCTACTTGGAACATCATCATCAGAAAACAGTCAGCCTGCTCATCTTCATGAACTGCTATGTTC ACTACAGAAACAGCTGCTGGCATTTTGCCATATCAATAACATTAGTGAGAACTCAAGCAGTGTGGCATTGCTTCATAAACATCTTCAGCT TTTGTTGCCTCATGCCACAGATATTTATTCACGTTCTGCAAATTTGCTCAAAGAAAGTCCTTGGAATGGCAGTGTTGGAGAAAAATTAAG AGATGTGATATACGTCTCAGCTGCTGGCAGTATGCTCTGCCAGATTGTTAACTCCCTGCTGTTACTCCCTGTGTCAGTGGCTCGGCCTTT ATTGAGTTACCTCCTCGACTTGTTGCCACCTCTTGATTGCCTTAATAGACTCCTGCCAGCTGCTGATCTTTTAGAAGACCAGGAGTTACA GTGGCCTCTTCATGGAGGGCCAGAACTAATTGATCCTGCTGGTCTGCCATTACCTCAGCCAGCTCAGTCCTGGGTATGGCTTGTGGATCT AGAAAGAACAATTGCTCTCCTTATTGGGCGGTGTCTTGGTGGCATGCTTCAGGGCTCCCCTGTGTCTCCAGAGGAACAGGACACTGCATA TTGGATGAAAACGCCACTGTTCAGTGACGGTGTAGAAATGGACACTCCTCAATTGGATAAATGTATGAGTTGCCTGTTAGAAGTAGCACT TTCTGGAAATGAAGAACAGAAGCCTTTTGATTATAAATTGCGGCCTGAAATTGCTGTCTATGTAGACTTGGCATTGGGTTGTTCTAAAGA GCCTGCCCGAAGCCTTTGGATCAGCATGCAGGACTATGCTGTTAGTAAAGATTGGGACAGTGCAACTTTAAGTAATGAGTCACTCTTGGA CACTGTGTCTAGATTTGTTCTTGCAGCTCTTCTGAAACACACAAATTTACTTAGTCAAGCATGTGGAGAAAGCCGATATCAACCTGGTAA ACACTTATCAGAAGTGTACCGTTGTGTATACAAAGTTCGAAGTCGTTTACTTGCTTGCAAGAACCTTGAACTTATTCAAACAAGGTCATC ATCACGGGACAGATGGATATCAGAAAACCAGGACTCTGCAGATGTTGATCCTCAGGAGCATTCATTTACTCGAACTATTGATGAAGAAGC TGAAATGGAAGAACAGGCTGAGAGAGACCGGGAAGAGGGGCATCCGGAGCCAGAGGATGAAGAGGAGGAACGGGAACATGAAGTGATGAC AGCTGGCAAAATCTTTCAGTGTTTCCTCTCAGCCCGTGAAGTAGCTCGTAGCCGAGACCGAGATAGAATGAACAGTGGGGCAGGGTCTGG GGCTCGAGCTGATGATCCACCTCCTCAGTCTCAGCAAGAGCGAAGGGTCAGCACAGACCTTCCTGAGGGTCAGGATGTGTACACTGCTGC ATGCAACTCCGTGATCCATCGGTGTGCCCTGTTAATATTAGGAGTAAGTCCTGTGATAGATGAGCTTCAGAAGCGAAGAGAAGAAGGACA GTTGCAGCAACCTTCAACAAGTGCCTCTGAAGGGGGTGGACTTATGACCAGGAGTGAAAGTCTTACTGCAGAGAGCCGGCTAGTCCACAC AAGCCCAAATTATAGACTGATCAAATCGAGGAGTGAATCTGATTTGTCTCAGCCTGAATCAGATGAAGAGGGTTACGCACTGAGTGGCAG ACGAAATGTTGATTTGGATTTGGCAGCATCTCACAGAAAGAGAGGTCCTATGCACAGTCAATTGGAATCCCTGAGTGACTCTTGGGCTCG CCTGAAACATAGCAGAGACTGGTTATGCAACTCCTCCTATTCCTTTGAGTCAGATTTTGATCTTACCAAGTCTTTGGGAGTTCACACTTT GATTGAAAATGTTGTAAGCTTTGTGAGTGGAGATGTGGGGAATGCCCCAGGTTTTAAAGAGCCAGAGGAAAGTATGTCTACAAGTCCCCA GGCCTCCATCATTGCAATGGAACAGCAGCAGTTAAGGGCAGAACTTCGTTTAGAGGCACTTCATCAGATCCTCGTTCTATTGTCTGGGAT GGAAGAAAAAGGTAGCATCTCACTGGCAGGAAGCAGATTGAGTTCAGGCTTCCAGTCCTCCACACTACTCACGTCTGTGAGGCTGCAGTT CCTAGCAGGGTGTTTTGGTTTAGGCACTGTTGGACACACAGGAGGCAAGGGAGAGAGTGGCCGATTGCATCACTATCAGAGTGTCTGGAG GAGAGCTCTTCGATTTCCTGGCCCAGAAGGAGTCACTGAGTGAGGAGGAGGCCACCAGCTTCATTAAGCAGATCCTGGATGGGGTGAACT ACCTTCACACAAAGAAAATTGCTCACTTTGATCTCAAGCCAGAAAACATTATGTTGTTAGACAAGAATATTCCCATTCCACACATCAAGC TGATTGACTTTGGTCTGGCTCACGAAATAGAAGATGGAGTTGAATTTAAGAATATTTTTGGGACGCCGGAATTTGTTGCTCCAGAAATTG TGAACTACGAGCCCCTGGGTCTGGAGGCTGACATGTGGAGCATAGGCGTCATCACCTACATCCTCTTAAGTGGAGCATCCCCTTTCCTGG GAGACACGAAGCAGGAAACACTGGCAAATATCACAGCAGTGAGTTACGACTTTGATGAGGAATTCTTCAGCCAGACGAGCGAGCTGGCCA AGGACTTTATTCGGAAGCTTCTGGTTAAAGAGACCCGGAAACGGCTCACAATCCAAGAGGCTCTCAGACACCCCTGGATCACGTCAAAAG GAGAAGGCAGAGCCCCTGAACAGCGGAAGACAGAGCCCACCCAGCTGAAGACCAAGCACCTGAGAGAGTACACTCTCAAATGCCACTCAA GCATGCCTCCCAACAACTCCTATGTCAACTTCGAGCGTTTTGCCTGTGTGGTGGAAGACGTGGCTCGGGTCGACCTGGGATGCCGTGCCC TGGTGGAGGCCCACGATACCATCCAGGACGATGTGGAGGCCCTGGTCTCCATCTTCAATGAGAAGGAAGCTTGGTACCGAGAGGAGAATG AGAGCGCCCGGCATGACCTGTCCCAGCTCAGGTATGAGTTCCGCAAGGTGGAGTCATTGAAGAAGCTGCTGCGAGAAGACATCCAGGCCA CGGGATGTAGCCTCGGAAGCATGGCCAGGAAACTGGACCATCTGCAAGCCCAGTTTGAGATTCTGAGGCAGGAGCTCTCCGCAGACCTGC AGTGGATTCAGGAGCTGGTGGGCAGCTTCCAGCTGGAGAGTGGGAGCTCTGAGGGCCTGGGCTCCACATTCTACCAGGACACCAGTGAAT |
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FusionGenePPI for HERC1_DAPK2 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| HERC1 | DFFA, PKM, EP300, ARF1, TSC2, CLTC, NOS2, SOX9, UBE2D3, BYSL, GRIPAP1, KCMF1, MYL12A, BAK1, BRCA1, MORC1, RSPH10B2, MLF1, ECHS1, RAPSN, DNM3, USP18, TFDP3, ARHGAP29, TTLL1, UNK, HERC2, HERC1, UBE2S, EGFR, SSH3, IFIT1B, WDFY3, TIGD6, CCDC65, GCNT3, TRPC4AP, CSNK1A1, NEUROG3, C1orf87, RAPGEF5, ZBBX, SMOX, TPTE2, ZNF610, FMO5, ZNF223, ZNF571, VPS36, ZNF555, RABGEF1, ZNF563, UBC | DAPK2 | DAPK2, APP, FAM9B, LLGL2, RACGAP1, TUBGCP5, KLC3 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for HERC1_DAPK2 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for HERC1_DAPK2 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
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