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Fusion gene ID: 1600 |
FusionGeneSummary for AMD1_EPG5 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: AMD1_EPG5 | Fusion gene ID: 1600 | Hgene | Tgene | Gene symbol | AMD1 | EPG5 | Gene ID | 262 | 57724 |
| Gene name | adenosylmethionine decarboxylase 1 | ectopic P-granules autophagy protein 5 homolog | |
| Synonyms | ADOMETDC|AMD|SAMDC | HEEW1|KIAA1632|VICIS | |
| Cytomap | 6q21 | 18q12.3-q21.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | S-adenosylmethionine decarboxylase proenzymeS-adenosylmethionine decarboxylase 1 | ectopic P granules protein 5 homolog | |
| Modification date | 20180523 | 20180523 | |
| UniProtAcc | P17707 | Q9HCE0 | |
| Ensembl transtripts involved in fusion gene | ENST00000368882, ENST00000368885, ENST00000451850, ENST00000368877, ENST00000368876, | ENST00000282041, ENST00000585906, | |
| Fusion gene scores | * DoF score | 6 X 4 X 3=72 | 3 X 3 X 3=27 |
| # samples | 6 | 3 | |
| ** MAII score | log2(6/72*10)=-0.263034405833794 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(3/27*10)=0.15200309344505 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
| Context | PubMed: AMD1 [Title/Abstract] AND EPG5 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | PRAD | TCGA-VP-A875-01A | AMD1 | chr6 | 111196418 | + | EPG5 | chr18 | 43479531 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 5UTR-3CDS | ENST00000368882 | ENST00000282041 | AMD1 | chr6 | 111196418 | + | EPG5 | chr18 | 43479531 | - |
| 5UTR-5UTR | ENST00000368882 | ENST00000585906 | AMD1 | chr6 | 111196418 | + | EPG5 | chr18 | 43479531 | - |
| In-frame | ENST00000368885 | ENST00000282041 | AMD1 | chr6 | 111196418 | + | EPG5 | chr18 | 43479531 | - |
| 5CDS-5UTR | ENST00000368885 | ENST00000585906 | AMD1 | chr6 | 111196418 | + | EPG5 | chr18 | 43479531 | - |
| In-frame | ENST00000451850 | ENST00000282041 | AMD1 | chr6 | 111196418 | + | EPG5 | chr18 | 43479531 | - |
| 5CDS-5UTR | ENST00000451850 | ENST00000585906 | AMD1 | chr6 | 111196418 | + | EPG5 | chr18 | 43479531 | - |
| In-frame | ENST00000368877 | ENST00000282041 | AMD1 | chr6 | 111196418 | + | EPG5 | chr18 | 43479531 | - |
| 5CDS-5UTR | ENST00000368877 | ENST00000585906 | AMD1 | chr6 | 111196418 | + | EPG5 | chr18 | 43479531 | - |
| intron-3CDS | ENST00000368876 | ENST00000282041 | AMD1 | chr6 | 111196418 | + | EPG5 | chr18 | 43479531 | - |
| intron-5UTR | ENST00000368876 | ENST00000585906 | AMD1 | chr6 | 111196418 | + | EPG5 | chr18 | 43479531 | - |
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FusionProtFeatures for AMD1_EPG5 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| AMD1 | EPG5 |
| Essential for biosynthesis of the polyamines spermidineand spermine. Promotes maintenance and self-renewal of embryonicstem cells, by maintaining spermine levels.{ECO:0000250|UniProtKB:P0DMN7}. | Involved in autophagy. May play a role in a late step ofautophagy, such as clearance of autophagosomal cargo.{ECO:0000269|PubMed:20550938, ECO:0000269|PubMed:23222957}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
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FusionGeneSequence for AMD1_EPG5 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_AMD1_ENST00000368885_chr6_111196418_+_EPG5_ENST00000282041_chr18_43479531_-_1068aa MEAAHFFEGTEKLLEVWFSRQQPDANQGSGDLRTIPRTAALRESQQVALDGELLDTMPKQYVNREEQTTLHLECRGSSGKKCQGAAVVTV QFEGMHKNEAISQQLHVLRKEVKQLQAEAAKPPSLNIVEAAVHAENLITALVNAYKLQPTPGIQKVGISLFFTIVDYVSDETQRHPPTRQ FFTSCIEILGQVFISGIKSECRKVLETILKNSRLCSLLSPFFTPNAAPAEFIQLYEQVVKFLSEDNSDMIFMLLTKFDLKQWLSATKPPL SDRTRLLESIHLALTAWGLEPDEDILMPFNLFCKHWTYLLLYQFPDQYSDILRLLMQSSAEQLLSPECWKATLRALGCCAPSCQQGAAST EGAVLPSSSDALLSDKQVMETIQWLSDFFYKLRLSKMDFKSFGLFSKWSPYMADVKTFLGYLVKRLIDLEMTCLAQDPTASRKTVLKSLH SVIIQLFKPWILVLEDNESSQQRHYPWLESDTVVASSIVQLFTDCIDSLHESFKDKLLPGDAGALWLHLMHYCEACTAPKMPEFILYAFH STYRKLPWKDLHPDQMLMEAFFKVERGSPKSCFLFLGSVLCEVNWVSVLSDAWNSSPHPETRSMIVCLLFMMILLAKEVQLVDQTDSPLL SLLGQTSSLSWHLVDIVSYQSVLSYFSSHYPPSIILAKESYAELIMKLLKVSAGLSIPTDSQKHLDAVPKCQAFTHQMVQFLSTLEQNGK ITLAVLEQEMSKLLDDIIVFNPPDMDSQTRHMALSSLFMEVLMMMNNATIPTAEFLRGSIRTWIGQKMHGLVVLPLLTAACQSLASVRHM AETTEACITAYFKESPLNQNSGWGPILVSLQVPELTMEEFLQECLTLGSYLTLYVYLLQCLNSEQTLRNEMKVLLILSKWLEQVYPSSVE EEAKLFLWWHQVLQLSLIQTEQNDSVLTESVIRILLLVQSRQNLVAEERLSSGILGAIGFGRKSPLSNRFRVVARSMAAFLSVQVPMEDQ >In-frame_AMD1_ENST00000451850_chr6_111196418_+_EPG5_ENST00000282041_chr18_43479531_-_1068aa MEAAHFFEGTEKLLEVWFSRQQPDANQGSGDLRTIPRTAALRESQQVALDGELLDTMPKQYVNREEQTTLHLECRGSSGKKCQGAAVVTV QFEGMHKNEAISQQLHVLRKEVKQLQAEAAKPPSLNIVEAAVHAENLITALVNAYKLQPTPGIQKVGISLFFTIVDYVSDETQRHPPTRQ FFTSCIEILGQVFISGIKSECRKVLETILKNSRLCSLLSPFFTPNAAPAEFIQLYEQVVKFLSEDNSDMIFMLLTKFDLKQWLSATKPPL SDRTRLLESIHLALTAWGLEPDEDILMPFNLFCKHWTYLLLYQFPDQYSDILRLLMQSSAEQLLSPECWKATLRALGCCAPSCQQGAAST EGAVLPSSSDALLSDKQVMETIQWLSDFFYKLRLSKMDFKSFGLFSKWSPYMADVKTFLGYLVKRLIDLEMTCLAQDPTASRKTVLKSLH SVIIQLFKPWILVLEDNESSQQRHYPWLESDTVVASSIVQLFTDCIDSLHESFKDKLLPGDAGALWLHLMHYCEACTAPKMPEFILYAFH STYRKLPWKDLHPDQMLMEAFFKVERGSPKSCFLFLGSVLCEVNWVSVLSDAWNSSPHPETRSMIVCLLFMMILLAKEVQLVDQTDSPLL SLLGQTSSLSWHLVDIVSYQSVLSYFSSHYPPSIILAKESYAELIMKLLKVSAGLSIPTDSQKHLDAVPKCQAFTHQMVQFLSTLEQNGK ITLAVLEQEMSKLLDDIIVFNPPDMDSQTRHMALSSLFMEVLMMMNNATIPTAEFLRGSIRTWIGQKMHGLVVLPLLTAACQSLASVRHM AETTEACITAYFKESPLNQNSGWGPILVSLQVPELTMEEFLQECLTLGSYLTLYVYLLQCLNSEQTLRNEMKVLLILSKWLEQVYPSSVE EEAKLFLWWHQVLQLSLIQTEQNDSVLTESVIRILLLVQSRQNLVAEERLSSGILGAIGFGRKSPLSNRFRVVARSMAAFLSVQVPMEDQ >In-frame_AMD1_ENST00000368877_chr6_111196418_+_EPG5_ENST00000282041_chr18_43479531_-_1068aa MEAAHFFEGTEKLLEVWFSRQQPDANQGSGDLRTIPRTAALRESQQVALDGELLDTMPKQYVNREEQTTLHLECRGSSGKKCQGAAVVTV QFEGMHKNEAISQQLHVLRKEVKQLQAEAAKPPSLNIVEAAVHAENLITALVNAYKLQPTPGIQKVGISLFFTIVDYVSDETQRHPPTRQ FFTSCIEILGQVFISGIKSECRKVLETILKNSRLCSLLSPFFTPNAAPAEFIQLYEQVVKFLSEDNSDMIFMLLTKFDLKQWLSATKPPL SDRTRLLESIHLALTAWGLEPDEDILMPFNLFCKHWTYLLLYQFPDQYSDILRLLMQSSAEQLLSPECWKATLRALGCCAPSCQQGAAST EGAVLPSSSDALLSDKQVMETIQWLSDFFYKLRLSKMDFKSFGLFSKWSPYMADVKTFLGYLVKRLIDLEMTCLAQDPTASRKTVLKSLH SVIIQLFKPWILVLEDNESSQQRHYPWLESDTVVASSIVQLFTDCIDSLHESFKDKLLPGDAGALWLHLMHYCEACTAPKMPEFILYAFH STYRKLPWKDLHPDQMLMEAFFKVERGSPKSCFLFLGSVLCEVNWVSVLSDAWNSSPHPETRSMIVCLLFMMILLAKEVQLVDQTDSPLL SLLGQTSSLSWHLVDIVSYQSVLSYFSSHYPPSIILAKESYAELIMKLLKVSAGLSIPTDSQKHLDAVPKCQAFTHQMVQFLSTLEQNGK ITLAVLEQEMSKLLDDIIVFNPPDMDSQTRHMALSSLFMEVLMMMNNATIPTAEFLRGSIRTWIGQKMHGLVVLPLLTAACQSLASVRHM AETTEACITAYFKESPLNQNSGWGPILVSLQVPELTMEEFLQECLTLGSYLTLYVYLLQCLNSEQTLRNEMKVLLILSKWLEQVYPSSVE EEAKLFLWWHQVLQLSLIQTEQNDSVLTESVIRILLLVQSRQNLVAEERLSSGILGAIGFGRKSPLSNRFRVVARSMAAFLSVQVPMEDQ |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_AMD1_ENST00000368885_chr6_111196418_+_EPG5_ENST00000282041_chr18_43479531_-_3204nt ATGGAAGCTGCACATTTTTTCGAAGGGACCGAGAAGCTGCTGGAGGTTTGGTTCTCCCGGCAGCAGCCCGACGCAAACCAAGGATCTGGG GATCTTCGCACTATCCCAAGAACCGCAGCTCTTCGGGAATCTCAGCAGGTTGCTCTGGATGGTGAGCTGTTAGACACAATGCCAAAGCAG TATGTGAATCGTGAAGAACAGACCACACTACATTTGGAGTGCAGAGGCAGCAGCGGTAAGAAATGCCAAGGAGCCGCAGTTGTCACGGTT CAGTTTGAAGGCATGCATAAGAATGAAGCCATAAGCCAACAGCTTCATGTTTTACGGAAGGAAGTGAAGCAGTTGCAAGCAGAAGCTGCT AAACCACCATCACTTAATATTGTGGAAGCTGCTGTACATGCAGAAAACTTGATCACGGCCTTAGTGAATGCCTACAAGTTGCAGCCTACA CCTGGGATTCAGAAAGTTGGCATTAGCCTTTTCTTTACTATTGTGGATTACGTCAGCGATGAGACGCAGCGTCATCCCCCAACAAGGCAG TTCTTTACTTCATGTATTGAGATCTTGGGACAGGTATTTATCAGTGGCATTAAATCAGAGTGCAGAAAAGTACTTGAAACCATTCTGAAG AACAGCAGGCTCTGCTCCCTGCTGTCTCCTTTCTTCACTCCCAATGCTGCACCTGCAGAGTTCATACAGCTGTATGAGCAAGTGGTGAAG TTTCTAAGTGAGGACAACAGTGATATGATTTTCATGCTGCTAACCAAGTTCGATCTTAAACAATGGTTAAGCGCCACTAAACCTCCTCTG TCTGATCGTACCAGGCTTCTGGAGTCCATTCACTTGGCACTTACTGCCTGGGGCCTTGAACCAGATGAGGATATTTTGATGCCATTTAAT CTTTTCTGTAAGCACTGGACTTATCTTCTTCTCTACCAGTTTCCTGACCAGTACAGTGACATTCTCAGGCTGCTTATGCAAAGCTCCGCG GAGCAGCTTCTGAGCCCCGAGTGTTGGAAGGCCACTCTGAGAGCCCTGGGCTGCTGCGCCCCCAGCTGCCAGCAGGGGGCAGCGTCCACC GAGGGCGCCGTGCTTCCCAGCTCTTCTGATGCTCTCTTGTCAGACAAGCAGGTAATGGAGACTATACAGTGGCTTTCAGACTTTTTTTAT AAGCTTCGGTTATCCAAGATGGACTTTAAAAGCTTTGGTTTATTCTCAAAATGGAGTCCTTATATGGCTGATGTGAAGACATTCTTGGGC TACCTTGTGAAAAGGCTGATTGACTTAGAAATGACCTGTTTGGCCCAAGACCCAACTGCCAGCAGGAAAACAGTGCTGAAATCCCTACAT TCAGTAATCATTCAGCTCTTTAAGCCATGGATCCTGGTTTTAGAGGACAACGAAAGCAGCCAACAGCGGCATTACCCCTGGCTAGAGAGT GATACTGTGGTGGCCTCAAGCATTGTGCAGCTGTTCACTGACTGTATTGACTCACTGCATGAGAGTTTTAAAGATAAGCTGTTGCCAGGT GATGCAGGAGCCCTTTGGTTGCACCTGATGCATTATTGTGAAGCATGTACAGCACCCAAAATGCCAGAGTTCATTCTGTACGCTTTCCAT AGCACGTACCGGAAACTGCCATGGAAGGACCTGCACCCTGACCAGATGCTCATGGAGGCCTTCTTCAAAGTGGAACGAGGAAGCCCCAAG AGCTGTTTCTTATTTTTGGGGTCTGTACTCTGTGAAGTCAACTGGGTTAGTGTGCTCTCTGATGCCTGGAATTCCAGTCCCCACCCAGAA ACCCGCAGCATGATTGTCTGCCTCCTTTTCATGATGATTTTATTGGCAAAGGAAGTTCAACTGGTAGACCAAACAGATTCACCTTTACTT AGTCTCCTTGGACAGACAAGCTCACTTTCATGGCATCTTGTGGATATTGTGTCGTACCAGAGTGTGCTAAGTTATTTCAGCAGCCATTAC CCGCCGTCCATCATCCTGGCAAAAGAATCTTATGCTGAATTAATCATGAAGCTCCTAAAAGTGTCTGCGGGCCTTTCTATTCCTACTGAC AGCCAGAAGCATCTTGATGCAGTTCCAAAATGCCAAGCTTTTACTCATCAGATGGTTCAATTCCTCAGCACCCTGGAACAAAATGGAAAA ATCACCTTAGCAGTCCTAGAACAGGAAATGTCTAAGCTCTTAGACGATATCATTGTCTTTAACCCGCCCGACATGGACAGCCAGACCCGC CACATGGCCCTCAGCAGCCTCTTTATGGAAGTCCTGATGATGATGAACAACGCGACTATTCCAACAGCAGAGTTCCTTCGGGGCAGTATC CGGACCTGGATTGGCCAAAAAATGCATGGGCTGGTGGTGCTGCCCCTTTTAACAGCAGCCTGCCAGAGCCTGGCGTCCGTCCGCCACATG GCTGAGACTACAGAAGCCTGCATCACTGCCTACTTCAAAGAAAGCCCTCTCAATCAGAATTCAGGATGGGGACCCATTCTGGTATCCCTT CAGGTTCCCGAGCTCACCATGGAAGAGTTCCTGCAGGAGTGCCTCACCTTGGGCAGTTACTTGACTCTTTACGTCTACTTGCTTCAGTGT TTAAACAGCGAACAGACTTTAAGGAATGAAATGAAAGTGCTGCTCATCTTAAGCAAGTGGCTGGAACAGGTGTACCCAAGCTCCGTGGAG GAAGAGGCAAAGCTGTTTTTGTGGTGGCACCAAGTCCTTCAGCTCTCCCTCATTCAGACAGAGCAGAATGACTCCGTCCTGACAGAATCT GTCATTCGAATTCTGCTCTTGGTTCAGAGCAGGCAGAACCTCGTGGCTGAGGAGAGACTCAGCTCTGGGATCCTGGGGGCAATTGGGTTT GGCCGGAAGTCGCCTTTGTCTAACAGGTTCCGAGTGGTTGCCCGAAGCATGGCTGCCTTCCTTTCAGTTCAGGTTCCTATGGAAGATCAG ATCCGTTTGAGGCCTGGCTCTGAATTACATCTGACCCCCAAAGCTCAGCAGGCTCTGAATGCTCTTGAATCCATGGCATCAAGTAAGCAG TATGTTGAATACCAGGATCAAATATTGCAAGCCACCCAATTTATAAGGCATCCTGGCCATTGCCTTCAAGATGGGAAAAGCTTCTTGGCT >In-frame_AMD1_ENST00000451850_chr6_111196418_+_EPG5_ENST00000282041_chr18_43479531_-_3204nt ATGGAAGCTGCACATTTTTTCGAAGGGACCGAGAAGCTGCTGGAGGTTTGGTTCTCCCGGCAGCAGCCCGACGCAAACCAAGGATCTGGG GATCTTCGCACTATCCCAAGAACCGCAGCTCTTCGGGAATCTCAGCAGGTTGCTCTGGATGGTGAGCTGTTAGACACAATGCCAAAGCAG TATGTGAATCGTGAAGAACAGACCACACTACATTTGGAGTGCAGAGGCAGCAGCGGTAAGAAATGCCAAGGAGCCGCAGTTGTCACGGTT CAGTTTGAAGGCATGCATAAGAATGAAGCCATAAGCCAACAGCTTCATGTTTTACGGAAGGAAGTGAAGCAGTTGCAAGCAGAAGCTGCT AAACCACCATCACTTAATATTGTGGAAGCTGCTGTACATGCAGAAAACTTGATCACGGCCTTAGTGAATGCCTACAAGTTGCAGCCTACA CCTGGGATTCAGAAAGTTGGCATTAGCCTTTTCTTTACTATTGTGGATTACGTCAGCGATGAGACGCAGCGTCATCCCCCAACAAGGCAG TTCTTTACTTCATGTATTGAGATCTTGGGACAGGTATTTATCAGTGGCATTAAATCAGAGTGCAGAAAAGTACTTGAAACCATTCTGAAG AACAGCAGGCTCTGCTCCCTGCTGTCTCCTTTCTTCACTCCCAATGCTGCACCTGCAGAGTTCATACAGCTGTATGAGCAAGTGGTGAAG TTTCTAAGTGAGGACAACAGTGATATGATTTTCATGCTGCTAACCAAGTTCGATCTTAAACAATGGTTAAGCGCCACTAAACCTCCTCTG TCTGATCGTACCAGGCTTCTGGAGTCCATTCACTTGGCACTTACTGCCTGGGGCCTTGAACCAGATGAGGATATTTTGATGCCATTTAAT CTTTTCTGTAAGCACTGGACTTATCTTCTTCTCTACCAGTTTCCTGACCAGTACAGTGACATTCTCAGGCTGCTTATGCAAAGCTCCGCG GAGCAGCTTCTGAGCCCCGAGTGTTGGAAGGCCACTCTGAGAGCCCTGGGCTGCTGCGCCCCCAGCTGCCAGCAGGGGGCAGCGTCCACC GAGGGCGCCGTGCTTCCCAGCTCTTCTGATGCTCTCTTGTCAGACAAGCAGGTAATGGAGACTATACAGTGGCTTTCAGACTTTTTTTAT AAGCTTCGGTTATCCAAGATGGACTTTAAAAGCTTTGGTTTATTCTCAAAATGGAGTCCTTATATGGCTGATGTGAAGACATTCTTGGGC TACCTTGTGAAAAGGCTGATTGACTTAGAAATGACCTGTTTGGCCCAAGACCCAACTGCCAGCAGGAAAACAGTGCTGAAATCCCTACAT TCAGTAATCATTCAGCTCTTTAAGCCATGGATCCTGGTTTTAGAGGACAACGAAAGCAGCCAACAGCGGCATTACCCCTGGCTAGAGAGT GATACTGTGGTGGCCTCAAGCATTGTGCAGCTGTTCACTGACTGTATTGACTCACTGCATGAGAGTTTTAAAGATAAGCTGTTGCCAGGT GATGCAGGAGCCCTTTGGTTGCACCTGATGCATTATTGTGAAGCATGTACAGCACCCAAAATGCCAGAGTTCATTCTGTACGCTTTCCAT AGCACGTACCGGAAACTGCCATGGAAGGACCTGCACCCTGACCAGATGCTCATGGAGGCCTTCTTCAAAGTGGAACGAGGAAGCCCCAAG AGCTGTTTCTTATTTTTGGGGTCTGTACTCTGTGAAGTCAACTGGGTTAGTGTGCTCTCTGATGCCTGGAATTCCAGTCCCCACCCAGAA ACCCGCAGCATGATTGTCTGCCTCCTTTTCATGATGATTTTATTGGCAAAGGAAGTTCAACTGGTAGACCAAACAGATTCACCTTTACTT AGTCTCCTTGGACAGACAAGCTCACTTTCATGGCATCTTGTGGATATTGTGTCGTACCAGAGTGTGCTAAGTTATTTCAGCAGCCATTAC CCGCCGTCCATCATCCTGGCAAAAGAATCTTATGCTGAATTAATCATGAAGCTCCTAAAAGTGTCTGCGGGCCTTTCTATTCCTACTGAC AGCCAGAAGCATCTTGATGCAGTTCCAAAATGCCAAGCTTTTACTCATCAGATGGTTCAATTCCTCAGCACCCTGGAACAAAATGGAAAA ATCACCTTAGCAGTCCTAGAACAGGAAATGTCTAAGCTCTTAGACGATATCATTGTCTTTAACCCGCCCGACATGGACAGCCAGACCCGC CACATGGCCCTCAGCAGCCTCTTTATGGAAGTCCTGATGATGATGAACAACGCGACTATTCCAACAGCAGAGTTCCTTCGGGGCAGTATC CGGACCTGGATTGGCCAAAAAATGCATGGGCTGGTGGTGCTGCCCCTTTTAACAGCAGCCTGCCAGAGCCTGGCGTCCGTCCGCCACATG GCTGAGACTACAGAAGCCTGCATCACTGCCTACTTCAAAGAAAGCCCTCTCAATCAGAATTCAGGATGGGGACCCATTCTGGTATCCCTT CAGGTTCCCGAGCTCACCATGGAAGAGTTCCTGCAGGAGTGCCTCACCTTGGGCAGTTACTTGACTCTTTACGTCTACTTGCTTCAGTGT TTAAACAGCGAACAGACTTTAAGGAATGAAATGAAAGTGCTGCTCATCTTAAGCAAGTGGCTGGAACAGGTGTACCCAAGCTCCGTGGAG GAAGAGGCAAAGCTGTTTTTGTGGTGGCACCAAGTCCTTCAGCTCTCCCTCATTCAGACAGAGCAGAATGACTCCGTCCTGACAGAATCT GTCATTCGAATTCTGCTCTTGGTTCAGAGCAGGCAGAACCTCGTGGCTGAGGAGAGACTCAGCTCTGGGATCCTGGGGGCAATTGGGTTT GGCCGGAAGTCGCCTTTGTCTAACAGGTTCCGAGTGGTTGCCCGAAGCATGGCTGCCTTCCTTTCAGTTCAGGTTCCTATGGAAGATCAG ATCCGTTTGAGGCCTGGCTCTGAATTACATCTGACCCCCAAAGCTCAGCAGGCTCTGAATGCTCTTGAATCCATGGCATCAAGTAAGCAG TATGTTGAATACCAGGATCAAATATTGCAAGCCACCCAATTTATAAGGCATCCTGGCCATTGCCTTCAAGATGGGAAAAGCTTCTTGGCT >In-frame_AMD1_ENST00000368877_chr6_111196418_+_EPG5_ENST00000282041_chr18_43479531_-_3204nt ATGGAAGCTGCACATTTTTTCGAAGGGACCGAGAAGCTGCTGGAGGTTTGGTTCTCCCGGCAGCAGCCCGACGCAAACCAAGGATCTGGG GATCTTCGCACTATCCCAAGAACCGCAGCTCTTCGGGAATCTCAGCAGGTTGCTCTGGATGGTGAGCTGTTAGACACAATGCCAAAGCAG TATGTGAATCGTGAAGAACAGACCACACTACATTTGGAGTGCAGAGGCAGCAGCGGTAAGAAATGCCAAGGAGCCGCAGTTGTCACGGTT CAGTTTGAAGGCATGCATAAGAATGAAGCCATAAGCCAACAGCTTCATGTTTTACGGAAGGAAGTGAAGCAGTTGCAAGCAGAAGCTGCT AAACCACCATCACTTAATATTGTGGAAGCTGCTGTACATGCAGAAAACTTGATCACGGCCTTAGTGAATGCCTACAAGTTGCAGCCTACA CCTGGGATTCAGAAAGTTGGCATTAGCCTTTTCTTTACTATTGTGGATTACGTCAGCGATGAGACGCAGCGTCATCCCCCAACAAGGCAG TTCTTTACTTCATGTATTGAGATCTTGGGACAGGTATTTATCAGTGGCATTAAATCAGAGTGCAGAAAAGTACTTGAAACCATTCTGAAG AACAGCAGGCTCTGCTCCCTGCTGTCTCCTTTCTTCACTCCCAATGCTGCACCTGCAGAGTTCATACAGCTGTATGAGCAAGTGGTGAAG TTTCTAAGTGAGGACAACAGTGATATGATTTTCATGCTGCTAACCAAGTTCGATCTTAAACAATGGTTAAGCGCCACTAAACCTCCTCTG TCTGATCGTACCAGGCTTCTGGAGTCCATTCACTTGGCACTTACTGCCTGGGGCCTTGAACCAGATGAGGATATTTTGATGCCATTTAAT CTTTTCTGTAAGCACTGGACTTATCTTCTTCTCTACCAGTTTCCTGACCAGTACAGTGACATTCTCAGGCTGCTTATGCAAAGCTCCGCG GAGCAGCTTCTGAGCCCCGAGTGTTGGAAGGCCACTCTGAGAGCCCTGGGCTGCTGCGCCCCCAGCTGCCAGCAGGGGGCAGCGTCCACC GAGGGCGCCGTGCTTCCCAGCTCTTCTGATGCTCTCTTGTCAGACAAGCAGGTAATGGAGACTATACAGTGGCTTTCAGACTTTTTTTAT AAGCTTCGGTTATCCAAGATGGACTTTAAAAGCTTTGGTTTATTCTCAAAATGGAGTCCTTATATGGCTGATGTGAAGACATTCTTGGGC TACCTTGTGAAAAGGCTGATTGACTTAGAAATGACCTGTTTGGCCCAAGACCCAACTGCCAGCAGGAAAACAGTGCTGAAATCCCTACAT TCAGTAATCATTCAGCTCTTTAAGCCATGGATCCTGGTTTTAGAGGACAACGAAAGCAGCCAACAGCGGCATTACCCCTGGCTAGAGAGT GATACTGTGGTGGCCTCAAGCATTGTGCAGCTGTTCACTGACTGTATTGACTCACTGCATGAGAGTTTTAAAGATAAGCTGTTGCCAGGT GATGCAGGAGCCCTTTGGTTGCACCTGATGCATTATTGTGAAGCATGTACAGCACCCAAAATGCCAGAGTTCATTCTGTACGCTTTCCAT AGCACGTACCGGAAACTGCCATGGAAGGACCTGCACCCTGACCAGATGCTCATGGAGGCCTTCTTCAAAGTGGAACGAGGAAGCCCCAAG AGCTGTTTCTTATTTTTGGGGTCTGTACTCTGTGAAGTCAACTGGGTTAGTGTGCTCTCTGATGCCTGGAATTCCAGTCCCCACCCAGAA ACCCGCAGCATGATTGTCTGCCTCCTTTTCATGATGATTTTATTGGCAAAGGAAGTTCAACTGGTAGACCAAACAGATTCACCTTTACTT AGTCTCCTTGGACAGACAAGCTCACTTTCATGGCATCTTGTGGATATTGTGTCGTACCAGAGTGTGCTAAGTTATTTCAGCAGCCATTAC CCGCCGTCCATCATCCTGGCAAAAGAATCTTATGCTGAATTAATCATGAAGCTCCTAAAAGTGTCTGCGGGCCTTTCTATTCCTACTGAC AGCCAGAAGCATCTTGATGCAGTTCCAAAATGCCAAGCTTTTACTCATCAGATGGTTCAATTCCTCAGCACCCTGGAACAAAATGGAAAA ATCACCTTAGCAGTCCTAGAACAGGAAATGTCTAAGCTCTTAGACGATATCATTGTCTTTAACCCGCCCGACATGGACAGCCAGACCCGC CACATGGCCCTCAGCAGCCTCTTTATGGAAGTCCTGATGATGATGAACAACGCGACTATTCCAACAGCAGAGTTCCTTCGGGGCAGTATC CGGACCTGGATTGGCCAAAAAATGCATGGGCTGGTGGTGCTGCCCCTTTTAACAGCAGCCTGCCAGAGCCTGGCGTCCGTCCGCCACATG GCTGAGACTACAGAAGCCTGCATCACTGCCTACTTCAAAGAAAGCCCTCTCAATCAGAATTCAGGATGGGGACCCATTCTGGTATCCCTT CAGGTTCCCGAGCTCACCATGGAAGAGTTCCTGCAGGAGTGCCTCACCTTGGGCAGTTACTTGACTCTTTACGTCTACTTGCTTCAGTGT TTAAACAGCGAACAGACTTTAAGGAATGAAATGAAAGTGCTGCTCATCTTAAGCAAGTGGCTGGAACAGGTGTACCCAAGCTCCGTGGAG GAAGAGGCAAAGCTGTTTTTGTGGTGGCACCAAGTCCTTCAGCTCTCCCTCATTCAGACAGAGCAGAATGACTCCGTCCTGACAGAATCT GTCATTCGAATTCTGCTCTTGGTTCAGAGCAGGCAGAACCTCGTGGCTGAGGAGAGACTCAGCTCTGGGATCCTGGGGGCAATTGGGTTT GGCCGGAAGTCGCCTTTGTCTAACAGGTTCCGAGTGGTTGCCCGAAGCATGGCTGCCTTCCTTTCAGTTCAGGTTCCTATGGAAGATCAG ATCCGTTTGAGGCCTGGCTCTGAATTACATCTGACCCCCAAAGCTCAGCAGGCTCTGAATGCTCTTGAATCCATGGCATCAAGTAAGCAG TATGTTGAATACCAGGATCAAATATTGCAAGCCACCCAATTTATAAGGCATCCTGGCCATTGCCTTCAAGATGGGAAAAGCTTCTTGGCT |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_AMD1_ENST00000368885_chr6_111196418_+_EPG5_ENST00000282041_chr18_43479531_-_8398nt TCACGCAGCGCTCTCGCTTACACAGTATGGCCGGCGACATTAGCTAGCGCTCGCTCTACTCTCTCTAACGGGAAAGCAGCGGAATACAAG AGACTGAACTGTATCTGCCTCTATTTCCAAAAGACTCACGTTCAACTTTCGCTCACACAAAGCCGGGAAAATTTTATTAGTCCTTTTTTT AAAAAAAGTTAATATAAAATTATAGCAAAAAAAAAAAGGAACCTGAACTTTAGTAACACAGCTGGAACAATCCGCAGCGGCGGCGGCAGC GGCGGGAGAAGAGGTTTAATTTAGTTGATTTTCTGTGGTTGTTGGTTGTTCGCTAGTCTCACGGTGATGGAAGCTGCACATTTTTTCGAA GGGACCGAGAAGCTGCTGGAGGTTTGGTTCTCCCGGCAGCAGCCCGACGCAAACCAAGGATCTGGGGATCTTCGCACTATCCCAAGAACC GCAGCTCTTCGGGAATCTCAGCAGGTTGCTCTGGATGGTGAGCTGTTAGACACAATGCCAAAGCAGTATGTGAATCGTGAAGAACAGACC ACACTACATTTGGAGTGCAGAGGCAGCAGCGGTAAGAAATGCCAAGGAGCCGCAGTTGTCACGGTTCAGTTTGAAGGCATGCATAAGAAT GAAGCCATAAGCCAACAGCTTCATGTTTTACGGAAGGAAGTGAAGCAGTTGCAAGCAGAAGCTGCTAAACCACCATCACTTAATATTGTG GAAGCTGCTGTACATGCAGAAAACTTGATCACGGCCTTAGTGAATGCCTACAAGTTGCAGCCTACACCTGGGATTCAGAAAGTTGGCATT AGCCTTTTCTTTACTATTGTGGATTACGTCAGCGATGAGACGCAGCGTCATCCCCCAACAAGGCAGTTCTTTACTTCATGTATTGAGATC TTGGGACAGGTATTTATCAGTGGCATTAAATCAGAGTGCAGAAAAGTACTTGAAACCATTCTGAAGAACAGCAGGCTCTGCTCCCTGCTG TCTCCTTTCTTCACTCCCAATGCTGCACCTGCAGAGTTCATACAGCTGTATGAGCAAGTGGTGAAGTTTCTAAGTGAGGACAACAGTGAT ATGATTTTCATGCTGCTAACCAAGTTCGATCTTAAACAATGGTTAAGCGCCACTAAACCTCCTCTGTCTGATCGTACCAGGCTTCTGGAG TCCATTCACTTGGCACTTACTGCCTGGGGCCTTGAACCAGATGAGGATATTTTGATGCCATTTAATCTTTTCTGTAAGCACTGGACTTAT CTTCTTCTCTACCAGTTTCCTGACCAGTACAGTGACATTCTCAGGCTGCTTATGCAAAGCTCCGCGGAGCAGCTTCTGAGCCCCGAGTGT TGGAAGGCCACTCTGAGAGCCCTGGGCTGCTGCGCCCCCAGCTGCCAGCAGGGGGCAGCGTCCACCGAGGGCGCCGTGCTTCCCAGCTCT TCTGATGCTCTCTTGTCAGACAAGCAGGTAATGGAGACTATACAGTGGCTTTCAGACTTTTTTTATAAGCTTCGGTTATCCAAGATGGAC TTTAAAAGCTTTGGTTTATTCTCAAAATGGAGTCCTTATATGGCTGATGTGAAGACATTCTTGGGCTACCTTGTGAAAAGGCTGATTGAC TTAGAAATGACCTGTTTGGCCCAAGACCCAACTGCCAGCAGGAAAACAGTGCTGAAATCCCTACATTCAGTAATCATTCAGCTCTTTAAG CCATGGATCCTGGTTTTAGAGGACAACGAAAGCAGCCAACAGCGGCATTACCCCTGGCTAGAGAGTGATACTGTGGTGGCCTCAAGCATT GTGCAGCTGTTCACTGACTGTATTGACTCACTGCATGAGAGTTTTAAAGATAAGCTGTTGCCAGGTGATGCAGGAGCCCTTTGGTTGCAC CTGATGCATTATTGTGAAGCATGTACAGCACCCAAAATGCCAGAGTTCATTCTGTACGCTTTCCATAGCACGTACCGGAAACTGCCATGG AAGGACCTGCACCCTGACCAGATGCTCATGGAGGCCTTCTTCAAAGTGGAACGAGGAAGCCCCAAGAGCTGTTTCTTATTTTTGGGGTCT GTACTCTGTGAAGTCAACTGGGTTAGTGTGCTCTCTGATGCCTGGAATTCCAGTCCCCACCCAGAAACCCGCAGCATGATTGTCTGCCTC CTTTTCATGATGATTTTATTGGCAAAGGAAGTTCAACTGGTAGACCAAACAGATTCACCTTTACTTAGTCTCCTTGGACAGACAAGCTCA CTTTCATGGCATCTTGTGGATATTGTGTCGTACCAGAGTGTGCTAAGTTATTTCAGCAGCCATTACCCGCCGTCCATCATCCTGGCAAAA GAATCTTATGCTGAATTAATCATGAAGCTCCTAAAAGTGTCTGCGGGCCTTTCTATTCCTACTGACAGCCAGAAGCATCTTGATGCAGTT CCAAAATGCCAAGCTTTTACTCATCAGATGGTTCAATTCCTCAGCACCCTGGAACAAAATGGAAAAATCACCTTAGCAGTCCTAGAACAG GAAATGTCTAAGCTCTTAGACGATATCATTGTCTTTAACCCGCCCGACATGGACAGCCAGACCCGCCACATGGCCCTCAGCAGCCTCTTT ATGGAAGTCCTGATGATGATGAACAACGCGACTATTCCAACAGCAGAGTTCCTTCGGGGCAGTATCCGGACCTGGATTGGCCAAAAAATG CATGGGCTGGTGGTGCTGCCCCTTTTAACAGCAGCCTGCCAGAGCCTGGCGTCCGTCCGCCACATGGCTGAGACTACAGAAGCCTGCATC ACTGCCTACTTCAAAGAAAGCCCTCTCAATCAGAATTCAGGATGGGGACCCATTCTGGTATCCCTTCAGGTTCCCGAGCTCACCATGGAA GAGTTCCTGCAGGAGTGCCTCACCTTGGGCAGTTACTTGACTCTTTACGTCTACTTGCTTCAGTGTTTAAACAGCGAACAGACTTTAAGG AATGAAATGAAAGTGCTGCTCATCTTAAGCAAGTGGCTGGAACAGGTGTACCCAAGCTCCGTGGAGGAAGAGGCAAAGCTGTTTTTGTGG TGGCACCAAGTCCTTCAGCTCTCCCTCATTCAGACAGAGCAGAATGACTCCGTCCTGACAGAATCTGTCATTCGAATTCTGCTCTTGGTT CAGAGCAGGCAGAACCTCGTGGCTGAGGAGAGACTCAGCTCTGGGATCCTGGGGGCAATTGGGTTTGGCCGGAAGTCGCCTTTGTCTAAC AGGTTCCGAGTGGTTGCCCGAAGCATGGCTGCCTTCCTTTCAGTTCAGGTTCCTATGGAAGATCAGATCCGTTTGAGGCCTGGCTCTGAA TTACATCTGACCCCCAAAGCTCAGCAGGCTCTGAATGCTCTTGAATCCATGGCATCAAGTAAGCAGTATGTTGAATACCAGGATCAAATA TTGCAAGCCACCCAATTTATAAGGCATCCTGGCCATTGCCTTCAAGATGGGAAAAGCTTCTTGGCTCTTCTCGTTAACTGTCTGTATCCA GAAGTGCATTATTTGGACCACATACGATAGTTAACACTGAGGCTCTTGAAAAACCCATTGCTGTTTATGTTTACATTTAACTTTGCTGTT GCACAAGTAACTTTGCTCAATTGCACTGTAGAGCTCAGTTTGGCCAATGTGTAGTTGACTGAGATGCAAGTTGGGAGGCGTTAGATATTA GATAATTTTGGGGTGTGTGTGTGTGTGTGTGTGTGTTTTCTTAGCTCTTAAGACCTTCTGGGGACTCTTTAAGTTTTTATATTTATCCAC AAGAGAAACTTACTAAGTTCCACTTGGGTGCAGAGCCACTCACAGTTGCCGAATGTCCCAGTCATCTCACAAGACCTCCAGATGGAGTTC TTTGTATGTTTCCACTTCTGTCTCTGTTTTATGTAAATGTTCCAGATCTGACAACCTTGGAAGTCACTCAGTACCCTTACTTTTAAACCC CATTTGTGTTCCTCCAAAGTAAAGAAGTCAATTTTGAAAAATTTCTGCATTTCTCAAATGTGGACAAATACAATAGTTTTAAAGTATTGT TTTTCTCAGAAGGGAGATAAAAATGCCGAGTTAGTTAAAGTGGGTCATGTGTAAAATACGACCACTTGATCGTGATTATAGTGGGCAGTA GAGATGATGACAAGTCAATTTCCATCCAGCCGTGTATCCTCATGGAGAAGCTGCCTGTCTGAATCAGGATGGCAAGCTGGCAGTCTGGGA GGAGCATGTTTTGCACAGATGTTTTGTTTGGTCCACTTGGTGAGGAGTGCAGACAGGGCTGCCTCTCTCTAGTCGGGAGAGTCTGTGCAT TCCCTCGGGCCCTGACCCTAGCCTCATTCACATCACTTGCCCCTGTCGACACCTAAGTTTGCACCCTTTGATAGACACCATGTTCGATAT CTGAAAGGCTCAGTGTCAGGAGACAGAGACTGAGGGAGACTGAAGACCTGATTCTCTGTTCCCTGCTTGTTTTTTAACTTCAAACTCAGA TGAAGCCAATGGACCTGCTGAAACACTTGTCTGTGGAAACTGGGTCAGGTCGGGAGATCTACTGAAATTTGGCTTTTTTTCCATAGCCAC GTGCCTTCTGTTGTTGACAGTTCATTCATTACCAAAGCCTGTGTGTAACTTTGCCTTGTTCTGTGGCCATCTTCTTGCTCATGTTATTTC TCCTGGGAATGAGCAGTTTGACTTCTGTTCCCACGTTCCTCATTCTATCAGCTCTAGATGGATTTTGCCTGCATAGCTGGCTTAATATGT CTTTGTGTATGGGTAGTCTGTAGCCTGAGAATATTTACCTAAAAATGTCTAAACAGCCACCAAGAATGTTTATAGGGGTATAGGAATATA GTTAACAGAGTGCTAATCTCTCCTCAAATGTCCTTTTGGAATGCTTCCCCCAAAATTGGGAAGTTGGTAGGAGCTTTTCTTTACTTTGAA TTTCTTTACTTGGACAGAACGATTCTGCCTTAAAGACACGCTTTGCAGCTCTGATAAAGAACATCCCTGTTTAGTCTCTTGAGTTTTACA GGCCACAAAATGTCCGTCTCAGAGGGATCTGTCTCAGCTTTTCTTATTTTTGCTTCTCTCCGTTTTCAAAATTAATCATCTTGTTCTCTG TATAAGAAAATTTGAGAAGCTGTGGACAATTTAATAGTCTGATCTGGCAACAGCGATTTTTGTTTGGAAATATTTTGTGTTTTCTTTGAG GAGGATATAATTACTGATATCCTAGGATGTGAAATTTTTGAGTGACAGTATGCACATTTTAAAGAAAATTATGATTAATCTGTATAATGT TTTTTGGTCTGTAAAAATTATAAAAAATAAAATCATTTATCTTTGGTTGTAACTGTTTAAAAACCAAATTATAGGGATATCACACTATCT TGTAAAGTGTTTCAGCTGTTAAAGTTGCTGTAGGTTTTTATGCCTGATGTCATTTAATTTATTTGACATTGAACTTCATTAATAATCAGA GATGGTCAGTGAAAGCGCTTCCTCTTTAACTCTTTCTTGCTTAACCTTGGAAGGTTGACTCAACTCCTAGGTGTCTATGGGAAACTCTGG GCTAGGAACGTGCTATAAAGACACTGAGCTAGTTCAGACATGGCCATGCTGCTGTAGCCTCCTGGGAAAGAAGGGCGGCAGAGAGACCAG CCCGCCTGTTGGCTTGCAGGGGTAATGAGCCTTGGCTTGAAAAAATTGTTGGCCTCCAGAGAGCACGGGGCTGTGGTTTCAGAATCAGTG ATGGGTGCCGCACATCAAGACGGGAATCAAGCAAGACCAAGGCCCTGTGGACTGAGCAGCGTGGAGGGCGAACGGCTGCAGGCTCCAGAC TTCACCACAGGGTGGCCAACAGTGGCATCGGGACCAAATAAAGATGTCTAACAGCTTCCTGGGAGCAGGAGGAGGCAGGATTCTGGTTGC CATGAAAAACATCTCTCTCCCTCTCCATCACTCCCCATGCTGCAGTGCACAGGTGGGTTGCAGAGGCAGGCTGCATCCCGGAATCATGTT GTCCCACTGCCTATTAATAGAACAAGTGAAGGGCAGAATGCTGGAACACACCAGACATAGAGGGAGGGAGGTCCTGCCAGATGTGTCTAC ACAACTGTCTACATAGCATGACAGTAGCAGTGGATTCGGGACCCACCTGTACATGTTTCCAAAGCTCCTTCCTGCACACTCGGGACCTCA GCTCCAAGGCGTGACTCATTTCTCAGTCTCACCATCCTTTGTTGGCTCAGACATCGCATGCCTCTGCCCCACTGGGGTTGTGTGCCTGCG TCTCTCACTTCTTTGAGGTTGGGGAAAGCCTAGTCCAGAAAATGAAAACCCATAGACCAGCCTAACTTCCTTTCAACCAAGTGACGGCCT CCTGGTTCCTCTCAGTTCATCATCAAAATCAGTGTGTACATGTCATACAAGCCAAGAGTGTTCATGTCCTCGTTCCTTTCAAATGAAGGT GATATATACTTTTTCACTGAGTTTTTATTCCTGAAATTCTTTCTTCTGGAGCAGGAAGCAAATGTCCTGGAATCGTAGACTTTTACAGTC AGAAGGGTCATTCACGTTCATCTAGTGCCCCTCTCACTCTGCAGGGATCCTCCTGCCTCTCCTCTGCCCCTGTCCAGTGCCTGGTGGTCC AGCCTGTGATGGGCAGGCCTAGGCTGCCATCCGCAGGCTCTGTAGTTCTGCTTTCTATTGAACCAAGATGTTTCTACGTTGCCTATTGGT CGTGGTTCTGTCCAGAGCAGTTCAGGCTGGGGCTGTTCACTTGCCCCTCCTTGAGGCAGACCTTTAGATATTTTCAGTTTTCATCACATG TCTAACACCACTTCCACCCCACCCCTCACCTCTTAGGCTAAATCCAAGCTAAATCCCCCAATGTCTTTTTTTTTTTTTTTTTTTTGAGAC GAGTCTCATCTGTCACCCAGGCTGGAGTGCAATGGCATGGTCTCGGCTCACTGCAACCTCCGCCTCCTGGGTTCAAGCTATTCTGCCTCA GCCTCCCAAGGAGCCAGGACTACAGGTGCATGCCACCACGCCCGGCTAATTTTTGTATTTTTTAGTAGAGACAGGGTTTCACCCAGCCAT TGAGACAAGCTGGTTTCAAACTCCTGACCTTGTGGTCCGCCCGCCCCGGCCTCCCAGAGTGCTGGGATTACAGGCGTGAGCCACCGCGCC CATCTCCCCTGCAATGTCTTTAGTTAGACCTTTTCCACCATCATGTCTAACTGGGCTACGGTTTGGGGAAAGTGTCCAAATTAGTCCGTG TTATCCTAAAAGGGGTGTGCCCCGGATTAGCAGGGCCAGGGCTAGGGTGAGACAAATGAGGCACCTGGGGCATACATTTAAGTTGGTGCT TGCTTGCAGGTGCCAAGAGAGTGCTTCCTTGGGTTTACCCCCGTGGTGCCTCCTTTACCTCATTCTGGCCCCAGCCCTGGGGTTAGAGTC GCACCAGTGTGGTCCAAGTGGCATAATTATCTCCCTAAATGCTTGGGCAGCATCAGCTTTCAGTAGCTGTGCCCCATGGGAGGCACATTA AGCTAGTGGCAAGTTGAGACTGCAGACCTCAGCTTAATATCAGTTGTTGCCCAAGACAGATCTCACCCCACATCTTCATGACAGGCCTAA CAACAAGGCACTTTGCCCTTAATCCTCTACTACTGCCTGCTCTTCATTTTGGGCCAACTGTACAGCTCATTTTGAGATAGTAGCTGATCA TTTTTCTGATCAGTTAACTTTGTCTTATTAAGCAAAATGGAGAATATAATGTTGGGAAATAAGTGTGTTGATTAAAAGAAAGTATCCCCT TCTACCATCTTCCATTTGTGTCTGGGTTGTGCTGGGTAAAGTTCTAGACTTACTAACGCAGACTTCATTTTGGTCCGGTTTCCACAGCAT GCCTCGGGCATCAGTGTCCAGGAGTAGCTGTATTTGAGGTTTCCTTCACTCTGGTAGGTTCCTGATTCCTGATGAAAATAACTTGAAAAA AAAATAATTATACTACTGATCCTCTTTTGGGATAATGAAATTGCGAAGGAATGTTGTTGATTATAACTTTTATTTTTTAATGTACAGATG TACTGTCTCTCATTGAGCACTGATAGAATTTATTTTTCTTTCAATAGTTTAAAATCACTTATGTGGAGACACATACTTAAGTGTGTTCAA CTCGTTTTCTTCCCACATATCTAGTGTGACCTTTAAAAACCACAACTTTATTTTGGACATTAAATGTGCAATATTCACTACTTATTCATT GTTCCACATTTTTCATACTTGTACAAAGGGTAAGTTTTTATATAATGGTGAGAAACAGGAAGAAATGACAACTGGTTAAGTAAAATTCTG >In-frame_AMD1_ENST00000451850_chr6_111196418_+_EPG5_ENST00000282041_chr18_43479531_-_8384nt CGCTTACACAGTATGGCCGGCGACATTAGCTAGCGCTCGCTCTACTCTCTCTAACGGGAAAGCAGCGGAATACAAGAGACTGAACTGTAT CTGCCTCTATTTCCAAAAGACTCACGTTCAACTTTCGCTCACACAAAGCCGGGAAAATTTTATTAGTCCTTTTTTTAAAAAAAGTTAATA TAAAATTATAGCAAAAAAAAAAAGGAACCTGAACTTTAGTAACACAGCTGGAACAATCCGCAGCGGCGGCGGCAGCGGCGGGAGAAGAGG TTTAATTTAGTTGATTTTCTGTGGTTGTTGGTTGTTCGCTAGTCTCACGGTGATGGAAGCTGCACATTTTTTCGAAGGGACCGAGAAGCT GCTGGAGGTTTGGTTCTCCCGGCAGCAGCCCGACGCAAACCAAGGATCTGGGGATCTTCGCACTATCCCAAGAACCGCAGCTCTTCGGGA ATCTCAGCAGGTTGCTCTGGATGGTGAGCTGTTAGACACAATGCCAAAGCAGTATGTGAATCGTGAAGAACAGACCACACTACATTTGGA GTGCAGAGGCAGCAGCGGTAAGAAATGCCAAGGAGCCGCAGTTGTCACGGTTCAGTTTGAAGGCATGCATAAGAATGAAGCCATAAGCCA ACAGCTTCATGTTTTACGGAAGGAAGTGAAGCAGTTGCAAGCAGAAGCTGCTAAACCACCATCACTTAATATTGTGGAAGCTGCTGTACA TGCAGAAAACTTGATCACGGCCTTAGTGAATGCCTACAAGTTGCAGCCTACACCTGGGATTCAGAAAGTTGGCATTAGCCTTTTCTTTAC TATTGTGGATTACGTCAGCGATGAGACGCAGCGTCATCCCCCAACAAGGCAGTTCTTTACTTCATGTATTGAGATCTTGGGACAGGTATT TATCAGTGGCATTAAATCAGAGTGCAGAAAAGTACTTGAAACCATTCTGAAGAACAGCAGGCTCTGCTCCCTGCTGTCTCCTTTCTTCAC TCCCAATGCTGCACCTGCAGAGTTCATACAGCTGTATGAGCAAGTGGTGAAGTTTCTAAGTGAGGACAACAGTGATATGATTTTCATGCT GCTAACCAAGTTCGATCTTAAACAATGGTTAAGCGCCACTAAACCTCCTCTGTCTGATCGTACCAGGCTTCTGGAGTCCATTCACTTGGC ACTTACTGCCTGGGGCCTTGAACCAGATGAGGATATTTTGATGCCATTTAATCTTTTCTGTAAGCACTGGACTTATCTTCTTCTCTACCA GTTTCCTGACCAGTACAGTGACATTCTCAGGCTGCTTATGCAAAGCTCCGCGGAGCAGCTTCTGAGCCCCGAGTGTTGGAAGGCCACTCT GAGAGCCCTGGGCTGCTGCGCCCCCAGCTGCCAGCAGGGGGCAGCGTCCACCGAGGGCGCCGTGCTTCCCAGCTCTTCTGATGCTCTCTT GTCAGACAAGCAGGTAATGGAGACTATACAGTGGCTTTCAGACTTTTTTTATAAGCTTCGGTTATCCAAGATGGACTTTAAAAGCTTTGG TTTATTCTCAAAATGGAGTCCTTATATGGCTGATGTGAAGACATTCTTGGGCTACCTTGTGAAAAGGCTGATTGACTTAGAAATGACCTG TTTGGCCCAAGACCCAACTGCCAGCAGGAAAACAGTGCTGAAATCCCTACATTCAGTAATCATTCAGCTCTTTAAGCCATGGATCCTGGT TTTAGAGGACAACGAAAGCAGCCAACAGCGGCATTACCCCTGGCTAGAGAGTGATACTGTGGTGGCCTCAAGCATTGTGCAGCTGTTCAC TGACTGTATTGACTCACTGCATGAGAGTTTTAAAGATAAGCTGTTGCCAGGTGATGCAGGAGCCCTTTGGTTGCACCTGATGCATTATTG TGAAGCATGTACAGCACCCAAAATGCCAGAGTTCATTCTGTACGCTTTCCATAGCACGTACCGGAAACTGCCATGGAAGGACCTGCACCC TGACCAGATGCTCATGGAGGCCTTCTTCAAAGTGGAACGAGGAAGCCCCAAGAGCTGTTTCTTATTTTTGGGGTCTGTACTCTGTGAAGT CAACTGGGTTAGTGTGCTCTCTGATGCCTGGAATTCCAGTCCCCACCCAGAAACCCGCAGCATGATTGTCTGCCTCCTTTTCATGATGAT TTTATTGGCAAAGGAAGTTCAACTGGTAGACCAAACAGATTCACCTTTACTTAGTCTCCTTGGACAGACAAGCTCACTTTCATGGCATCT TGTGGATATTGTGTCGTACCAGAGTGTGCTAAGTTATTTCAGCAGCCATTACCCGCCGTCCATCATCCTGGCAAAAGAATCTTATGCTGA ATTAATCATGAAGCTCCTAAAAGTGTCTGCGGGCCTTTCTATTCCTACTGACAGCCAGAAGCATCTTGATGCAGTTCCAAAATGCCAAGC TTTTACTCATCAGATGGTTCAATTCCTCAGCACCCTGGAACAAAATGGAAAAATCACCTTAGCAGTCCTAGAACAGGAAATGTCTAAGCT CTTAGACGATATCATTGTCTTTAACCCGCCCGACATGGACAGCCAGACCCGCCACATGGCCCTCAGCAGCCTCTTTATGGAAGTCCTGAT GATGATGAACAACGCGACTATTCCAACAGCAGAGTTCCTTCGGGGCAGTATCCGGACCTGGATTGGCCAAAAAATGCATGGGCTGGTGGT GCTGCCCCTTTTAACAGCAGCCTGCCAGAGCCTGGCGTCCGTCCGCCACATGGCTGAGACTACAGAAGCCTGCATCACTGCCTACTTCAA AGAAAGCCCTCTCAATCAGAATTCAGGATGGGGACCCATTCTGGTATCCCTTCAGGTTCCCGAGCTCACCATGGAAGAGTTCCTGCAGGA GTGCCTCACCTTGGGCAGTTACTTGACTCTTTACGTCTACTTGCTTCAGTGTTTAAACAGCGAACAGACTTTAAGGAATGAAATGAAAGT GCTGCTCATCTTAAGCAAGTGGCTGGAACAGGTGTACCCAAGCTCCGTGGAGGAAGAGGCAAAGCTGTTTTTGTGGTGGCACCAAGTCCT TCAGCTCTCCCTCATTCAGACAGAGCAGAATGACTCCGTCCTGACAGAATCTGTCATTCGAATTCTGCTCTTGGTTCAGAGCAGGCAGAA CCTCGTGGCTGAGGAGAGACTCAGCTCTGGGATCCTGGGGGCAATTGGGTTTGGCCGGAAGTCGCCTTTGTCTAACAGGTTCCGAGTGGT TGCCCGAAGCATGGCTGCCTTCCTTTCAGTTCAGGTTCCTATGGAAGATCAGATCCGTTTGAGGCCTGGCTCTGAATTACATCTGACCCC CAAAGCTCAGCAGGCTCTGAATGCTCTTGAATCCATGGCATCAAGTAAGCAGTATGTTGAATACCAGGATCAAATATTGCAAGCCACCCA ATTTATAAGGCATCCTGGCCATTGCCTTCAAGATGGGAAAAGCTTCTTGGCTCTTCTCGTTAACTGTCTGTATCCAGAAGTGCATTATTT GGACCACATACGATAGTTAACACTGAGGCTCTTGAAAAACCCATTGCTGTTTATGTTTACATTTAACTTTGCTGTTGCACAAGTAACTTT GCTCAATTGCACTGTAGAGCTCAGTTTGGCCAATGTGTAGTTGACTGAGATGCAAGTTGGGAGGCGTTAGATATTAGATAATTTTGGGGT GTGTGTGTGTGTGTGTGTGTGTTTTCTTAGCTCTTAAGACCTTCTGGGGACTCTTTAAGTTTTTATATTTATCCACAAGAGAAACTTACT AAGTTCCACTTGGGTGCAGAGCCACTCACAGTTGCCGAATGTCCCAGTCATCTCACAAGACCTCCAGATGGAGTTCTTTGTATGTTTCCA CTTCTGTCTCTGTTTTATGTAAATGTTCCAGATCTGACAACCTTGGAAGTCACTCAGTACCCTTACTTTTAAACCCCATTTGTGTTCCTC CAAAGTAAAGAAGTCAATTTTGAAAAATTTCTGCATTTCTCAAATGTGGACAAATACAATAGTTTTAAAGTATTGTTTTTCTCAGAAGGG AGATAAAAATGCCGAGTTAGTTAAAGTGGGTCATGTGTAAAATACGACCACTTGATCGTGATTATAGTGGGCAGTAGAGATGATGACAAG TCAATTTCCATCCAGCCGTGTATCCTCATGGAGAAGCTGCCTGTCTGAATCAGGATGGCAAGCTGGCAGTCTGGGAGGAGCATGTTTTGC ACAGATGTTTTGTTTGGTCCACTTGGTGAGGAGTGCAGACAGGGCTGCCTCTCTCTAGTCGGGAGAGTCTGTGCATTCCCTCGGGCCCTG ACCCTAGCCTCATTCACATCACTTGCCCCTGTCGACACCTAAGTTTGCACCCTTTGATAGACACCATGTTCGATATCTGAAAGGCTCAGT GTCAGGAGACAGAGACTGAGGGAGACTGAAGACCTGATTCTCTGTTCCCTGCTTGTTTTTTAACTTCAAACTCAGATGAAGCCAATGGAC CTGCTGAAACACTTGTCTGTGGAAACTGGGTCAGGTCGGGAGATCTACTGAAATTTGGCTTTTTTTCCATAGCCACGTGCCTTCTGTTGT TGACAGTTCATTCATTACCAAAGCCTGTGTGTAACTTTGCCTTGTTCTGTGGCCATCTTCTTGCTCATGTTATTTCTCCTGGGAATGAGC AGTTTGACTTCTGTTCCCACGTTCCTCATTCTATCAGCTCTAGATGGATTTTGCCTGCATAGCTGGCTTAATATGTCTTTGTGTATGGGT AGTCTGTAGCCTGAGAATATTTACCTAAAAATGTCTAAACAGCCACCAAGAATGTTTATAGGGGTATAGGAATATAGTTAACAGAGTGCT AATCTCTCCTCAAATGTCCTTTTGGAATGCTTCCCCCAAAATTGGGAAGTTGGTAGGAGCTTTTCTTTACTTTGAATTTCTTTACTTGGA CAGAACGATTCTGCCTTAAAGACACGCTTTGCAGCTCTGATAAAGAACATCCCTGTTTAGTCTCTTGAGTTTTACAGGCCACAAAATGTC CGTCTCAGAGGGATCTGTCTCAGCTTTTCTTATTTTTGCTTCTCTCCGTTTTCAAAATTAATCATCTTGTTCTCTGTATAAGAAAATTTG AGAAGCTGTGGACAATTTAATAGTCTGATCTGGCAACAGCGATTTTTGTTTGGAAATATTTTGTGTTTTCTTTGAGGAGGATATAATTAC TGATATCCTAGGATGTGAAATTTTTGAGTGACAGTATGCACATTTTAAAGAAAATTATGATTAATCTGTATAATGTTTTTTGGTCTGTAA AAATTATAAAAAATAAAATCATTTATCTTTGGTTGTAACTGTTTAAAAACCAAATTATAGGGATATCACACTATCTTGTAAAGTGTTTCA GCTGTTAAAGTTGCTGTAGGTTTTTATGCCTGATGTCATTTAATTTATTTGACATTGAACTTCATTAATAATCAGAGATGGTCAGTGAAA GCGCTTCCTCTTTAACTCTTTCTTGCTTAACCTTGGAAGGTTGACTCAACTCCTAGGTGTCTATGGGAAACTCTGGGCTAGGAACGTGCT ATAAAGACACTGAGCTAGTTCAGACATGGCCATGCTGCTGTAGCCTCCTGGGAAAGAAGGGCGGCAGAGAGACCAGCCCGCCTGTTGGCT TGCAGGGGTAATGAGCCTTGGCTTGAAAAAATTGTTGGCCTCCAGAGAGCACGGGGCTGTGGTTTCAGAATCAGTGATGGGTGCCGCACA TCAAGACGGGAATCAAGCAAGACCAAGGCCCTGTGGACTGAGCAGCGTGGAGGGCGAACGGCTGCAGGCTCCAGACTTCACCACAGGGTG GCCAACAGTGGCATCGGGACCAAATAAAGATGTCTAACAGCTTCCTGGGAGCAGGAGGAGGCAGGATTCTGGTTGCCATGAAAAACATCT CTCTCCCTCTCCATCACTCCCCATGCTGCAGTGCACAGGTGGGTTGCAGAGGCAGGCTGCATCCCGGAATCATGTTGTCCCACTGCCTAT TAATAGAACAAGTGAAGGGCAGAATGCTGGAACACACCAGACATAGAGGGAGGGAGGTCCTGCCAGATGTGTCTACACAACTGTCTACAT AGCATGACAGTAGCAGTGGATTCGGGACCCACCTGTACATGTTTCCAAAGCTCCTTCCTGCACACTCGGGACCTCAGCTCCAAGGCGTGA CTCATTTCTCAGTCTCACCATCCTTTGTTGGCTCAGACATCGCATGCCTCTGCCCCACTGGGGTTGTGTGCCTGCGTCTCTCACTTCTTT GAGGTTGGGGAAAGCCTAGTCCAGAAAATGAAAACCCATAGACCAGCCTAACTTCCTTTCAACCAAGTGACGGCCTCCTGGTTCCTCTCA GTTCATCATCAAAATCAGTGTGTACATGTCATACAAGCCAAGAGTGTTCATGTCCTCGTTCCTTTCAAATGAAGGTGATATATACTTTTT CACTGAGTTTTTATTCCTGAAATTCTTTCTTCTGGAGCAGGAAGCAAATGTCCTGGAATCGTAGACTTTTACAGTCAGAAGGGTCATTCA CGTTCATCTAGTGCCCCTCTCACTCTGCAGGGATCCTCCTGCCTCTCCTCTGCCCCTGTCCAGTGCCTGGTGGTCCAGCCTGTGATGGGC AGGCCTAGGCTGCCATCCGCAGGCTCTGTAGTTCTGCTTTCTATTGAACCAAGATGTTTCTACGTTGCCTATTGGTCGTGGTTCTGTCCA GAGCAGTTCAGGCTGGGGCTGTTCACTTGCCCCTCCTTGAGGCAGACCTTTAGATATTTTCAGTTTTCATCACATGTCTAACACCACTTC CACCCCACCCCTCACCTCTTAGGCTAAATCCAAGCTAAATCCCCCAATGTCTTTTTTTTTTTTTTTTTTTTGAGACGAGTCTCATCTGTC ACCCAGGCTGGAGTGCAATGGCATGGTCTCGGCTCACTGCAACCTCCGCCTCCTGGGTTCAAGCTATTCTGCCTCAGCCTCCCAAGGAGC CAGGACTACAGGTGCATGCCACCACGCCCGGCTAATTTTTGTATTTTTTAGTAGAGACAGGGTTTCACCCAGCCATTGAGACAAGCTGGT TTCAAACTCCTGACCTTGTGGTCCGCCCGCCCCGGCCTCCCAGAGTGCTGGGATTACAGGCGTGAGCCACCGCGCCCATCTCCCCTGCAA TGTCTTTAGTTAGACCTTTTCCACCATCATGTCTAACTGGGCTACGGTTTGGGGAAAGTGTCCAAATTAGTCCGTGTTATCCTAAAAGGG GTGTGCCCCGGATTAGCAGGGCCAGGGCTAGGGTGAGACAAATGAGGCACCTGGGGCATACATTTAAGTTGGTGCTTGCTTGCAGGTGCC AAGAGAGTGCTTCCTTGGGTTTACCCCCGTGGTGCCTCCTTTACCTCATTCTGGCCCCAGCCCTGGGGTTAGAGTCGCACCAGTGTGGTC CAAGTGGCATAATTATCTCCCTAAATGCTTGGGCAGCATCAGCTTTCAGTAGCTGTGCCCCATGGGAGGCACATTAAGCTAGTGGCAAGT TGAGACTGCAGACCTCAGCTTAATATCAGTTGTTGCCCAAGACAGATCTCACCCCACATCTTCATGACAGGCCTAACAACAAGGCACTTT GCCCTTAATCCTCTACTACTGCCTGCTCTTCATTTTGGGCCAACTGTACAGCTCATTTTGAGATAGTAGCTGATCATTTTTCTGATCAGT TAACTTTGTCTTATTAAGCAAAATGGAGAATATAATGTTGGGAAATAAGTGTGTTGATTAAAAGAAAGTATCCCCTTCTACCATCTTCCA TTTGTGTCTGGGTTGTGCTGGGTAAAGTTCTAGACTTACTAACGCAGACTTCATTTTGGTCCGGTTTCCACAGCATGCCTCGGGCATCAG TGTCCAGGAGTAGCTGTATTTGAGGTTTCCTTCACTCTGGTAGGTTCCTGATTCCTGATGAAAATAACTTGAAAAAAAAATAATTATACT ACTGATCCTCTTTTGGGATAATGAAATTGCGAAGGAATGTTGTTGATTATAACTTTTATTTTTTAATGTACAGATGTACTGTCTCTCATT GAGCACTGATAGAATTTATTTTTCTTTCAATAGTTTAAAATCACTTATGTGGAGACACATACTTAAGTGTGTTCAACTCGTTTTCTTCCC ACATATCTAGTGTGACCTTTAAAAACCACAACTTTATTTTGGACATTAAATGTGCAATATTCACTACTTATTCATTGTTCCACATTTTTC ATACTTGTACAAAGGGTAAGTTTTTATATAATGGTGAGAAACAGGAAGAAATGACAACTGGTTAAGTAAAATTCTGCAAATAAACTAGAT >In-frame_AMD1_ENST00000368877_chr6_111196418_+_EPG5_ENST00000282041_chr18_43479531_-_8383nt GCTTACACAGTATGGCCGGCGACATTAGCTAGCGCTCGCTCTACTCTCTCTAACGGGAAAGCAGCGGAATACAAGAGACTGAACTGTATC TGCCTCTATTTCCAAAAGACTCACGTTCAACTTTCGCTCACACAAAGCCGGGAAAATTTTATTAGTCCTTTTTTTAAAAAAAGTTAATAT AAAATTATAGCAAAAAAAAAAAGGAACCTGAACTTTAGTAACACAGCTGGAACAATCCGCAGCGGCGGCGGCAGCGGCGGGAGAAGAGGT TTAATTTAGTTGATTTTCTGTGGTTGTTGGTTGTTCGCTAGTCTCACGGTGATGGAAGCTGCACATTTTTTCGAAGGGACCGAGAAGCTG CTGGAGGTTTGGTTCTCCCGGCAGCAGCCCGACGCAAACCAAGGATCTGGGGATCTTCGCACTATCCCAAGAACCGCAGCTCTTCGGGAA TCTCAGCAGGTTGCTCTGGATGGTGAGCTGTTAGACACAATGCCAAAGCAGTATGTGAATCGTGAAGAACAGACCACACTACATTTGGAG TGCAGAGGCAGCAGCGGTAAGAAATGCCAAGGAGCCGCAGTTGTCACGGTTCAGTTTGAAGGCATGCATAAGAATGAAGCCATAAGCCAA CAGCTTCATGTTTTACGGAAGGAAGTGAAGCAGTTGCAAGCAGAAGCTGCTAAACCACCATCACTTAATATTGTGGAAGCTGCTGTACAT GCAGAAAACTTGATCACGGCCTTAGTGAATGCCTACAAGTTGCAGCCTACACCTGGGATTCAGAAAGTTGGCATTAGCCTTTTCTTTACT ATTGTGGATTACGTCAGCGATGAGACGCAGCGTCATCCCCCAACAAGGCAGTTCTTTACTTCATGTATTGAGATCTTGGGACAGGTATTT ATCAGTGGCATTAAATCAGAGTGCAGAAAAGTACTTGAAACCATTCTGAAGAACAGCAGGCTCTGCTCCCTGCTGTCTCCTTTCTTCACT CCCAATGCTGCACCTGCAGAGTTCATACAGCTGTATGAGCAAGTGGTGAAGTTTCTAAGTGAGGACAACAGTGATATGATTTTCATGCTG CTAACCAAGTTCGATCTTAAACAATGGTTAAGCGCCACTAAACCTCCTCTGTCTGATCGTACCAGGCTTCTGGAGTCCATTCACTTGGCA CTTACTGCCTGGGGCCTTGAACCAGATGAGGATATTTTGATGCCATTTAATCTTTTCTGTAAGCACTGGACTTATCTTCTTCTCTACCAG TTTCCTGACCAGTACAGTGACATTCTCAGGCTGCTTATGCAAAGCTCCGCGGAGCAGCTTCTGAGCCCCGAGTGTTGGAAGGCCACTCTG AGAGCCCTGGGCTGCTGCGCCCCCAGCTGCCAGCAGGGGGCAGCGTCCACCGAGGGCGCCGTGCTTCCCAGCTCTTCTGATGCTCTCTTG TCAGACAAGCAGGTAATGGAGACTATACAGTGGCTTTCAGACTTTTTTTATAAGCTTCGGTTATCCAAGATGGACTTTAAAAGCTTTGGT TTATTCTCAAAATGGAGTCCTTATATGGCTGATGTGAAGACATTCTTGGGCTACCTTGTGAAAAGGCTGATTGACTTAGAAATGACCTGT TTGGCCCAAGACCCAACTGCCAGCAGGAAAACAGTGCTGAAATCCCTACATTCAGTAATCATTCAGCTCTTTAAGCCATGGATCCTGGTT TTAGAGGACAACGAAAGCAGCCAACAGCGGCATTACCCCTGGCTAGAGAGTGATACTGTGGTGGCCTCAAGCATTGTGCAGCTGTTCACT GACTGTATTGACTCACTGCATGAGAGTTTTAAAGATAAGCTGTTGCCAGGTGATGCAGGAGCCCTTTGGTTGCACCTGATGCATTATTGT GAAGCATGTACAGCACCCAAAATGCCAGAGTTCATTCTGTACGCTTTCCATAGCACGTACCGGAAACTGCCATGGAAGGACCTGCACCCT GACCAGATGCTCATGGAGGCCTTCTTCAAAGTGGAACGAGGAAGCCCCAAGAGCTGTTTCTTATTTTTGGGGTCTGTACTCTGTGAAGTC AACTGGGTTAGTGTGCTCTCTGATGCCTGGAATTCCAGTCCCCACCCAGAAACCCGCAGCATGATTGTCTGCCTCCTTTTCATGATGATT TTATTGGCAAAGGAAGTTCAACTGGTAGACCAAACAGATTCACCTTTACTTAGTCTCCTTGGACAGACAAGCTCACTTTCATGGCATCTT GTGGATATTGTGTCGTACCAGAGTGTGCTAAGTTATTTCAGCAGCCATTACCCGCCGTCCATCATCCTGGCAAAAGAATCTTATGCTGAA TTAATCATGAAGCTCCTAAAAGTGTCTGCGGGCCTTTCTATTCCTACTGACAGCCAGAAGCATCTTGATGCAGTTCCAAAATGCCAAGCT TTTACTCATCAGATGGTTCAATTCCTCAGCACCCTGGAACAAAATGGAAAAATCACCTTAGCAGTCCTAGAACAGGAAATGTCTAAGCTC TTAGACGATATCATTGTCTTTAACCCGCCCGACATGGACAGCCAGACCCGCCACATGGCCCTCAGCAGCCTCTTTATGGAAGTCCTGATG ATGATGAACAACGCGACTATTCCAACAGCAGAGTTCCTTCGGGGCAGTATCCGGACCTGGATTGGCCAAAAAATGCATGGGCTGGTGGTG CTGCCCCTTTTAACAGCAGCCTGCCAGAGCCTGGCGTCCGTCCGCCACATGGCTGAGACTACAGAAGCCTGCATCACTGCCTACTTCAAA GAAAGCCCTCTCAATCAGAATTCAGGATGGGGACCCATTCTGGTATCCCTTCAGGTTCCCGAGCTCACCATGGAAGAGTTCCTGCAGGAG TGCCTCACCTTGGGCAGTTACTTGACTCTTTACGTCTACTTGCTTCAGTGTTTAAACAGCGAACAGACTTTAAGGAATGAAATGAAAGTG CTGCTCATCTTAAGCAAGTGGCTGGAACAGGTGTACCCAAGCTCCGTGGAGGAAGAGGCAAAGCTGTTTTTGTGGTGGCACCAAGTCCTT CAGCTCTCCCTCATTCAGACAGAGCAGAATGACTCCGTCCTGACAGAATCTGTCATTCGAATTCTGCTCTTGGTTCAGAGCAGGCAGAAC CTCGTGGCTGAGGAGAGACTCAGCTCTGGGATCCTGGGGGCAATTGGGTTTGGCCGGAAGTCGCCTTTGTCTAACAGGTTCCGAGTGGTT GCCCGAAGCATGGCTGCCTTCCTTTCAGTTCAGGTTCCTATGGAAGATCAGATCCGTTTGAGGCCTGGCTCTGAATTACATCTGACCCCC AAAGCTCAGCAGGCTCTGAATGCTCTTGAATCCATGGCATCAAGTAAGCAGTATGTTGAATACCAGGATCAAATATTGCAAGCCACCCAA TTTATAAGGCATCCTGGCCATTGCCTTCAAGATGGGAAAAGCTTCTTGGCTCTTCTCGTTAACTGTCTGTATCCAGAAGTGCATTATTTG GACCACATACGATAGTTAACACTGAGGCTCTTGAAAAACCCATTGCTGTTTATGTTTACATTTAACTTTGCTGTTGCACAAGTAACTTTG CTCAATTGCACTGTAGAGCTCAGTTTGGCCAATGTGTAGTTGACTGAGATGCAAGTTGGGAGGCGTTAGATATTAGATAATTTTGGGGTG TGTGTGTGTGTGTGTGTGTGTTTTCTTAGCTCTTAAGACCTTCTGGGGACTCTTTAAGTTTTTATATTTATCCACAAGAGAAACTTACTA AGTTCCACTTGGGTGCAGAGCCACTCACAGTTGCCGAATGTCCCAGTCATCTCACAAGACCTCCAGATGGAGTTCTTTGTATGTTTCCAC TTCTGTCTCTGTTTTATGTAAATGTTCCAGATCTGACAACCTTGGAAGTCACTCAGTACCCTTACTTTTAAACCCCATTTGTGTTCCTCC AAAGTAAAGAAGTCAATTTTGAAAAATTTCTGCATTTCTCAAATGTGGACAAATACAATAGTTTTAAAGTATTGTTTTTCTCAGAAGGGA GATAAAAATGCCGAGTTAGTTAAAGTGGGTCATGTGTAAAATACGACCACTTGATCGTGATTATAGTGGGCAGTAGAGATGATGACAAGT CAATTTCCATCCAGCCGTGTATCCTCATGGAGAAGCTGCCTGTCTGAATCAGGATGGCAAGCTGGCAGTCTGGGAGGAGCATGTTTTGCA CAGATGTTTTGTTTGGTCCACTTGGTGAGGAGTGCAGACAGGGCTGCCTCTCTCTAGTCGGGAGAGTCTGTGCATTCCCTCGGGCCCTGA CCCTAGCCTCATTCACATCACTTGCCCCTGTCGACACCTAAGTTTGCACCCTTTGATAGACACCATGTTCGATATCTGAAAGGCTCAGTG TCAGGAGACAGAGACTGAGGGAGACTGAAGACCTGATTCTCTGTTCCCTGCTTGTTTTTTAACTTCAAACTCAGATGAAGCCAATGGACC TGCTGAAACACTTGTCTGTGGAAACTGGGTCAGGTCGGGAGATCTACTGAAATTTGGCTTTTTTTCCATAGCCACGTGCCTTCTGTTGTT GACAGTTCATTCATTACCAAAGCCTGTGTGTAACTTTGCCTTGTTCTGTGGCCATCTTCTTGCTCATGTTATTTCTCCTGGGAATGAGCA GTTTGACTTCTGTTCCCACGTTCCTCATTCTATCAGCTCTAGATGGATTTTGCCTGCATAGCTGGCTTAATATGTCTTTGTGTATGGGTA GTCTGTAGCCTGAGAATATTTACCTAAAAATGTCTAAACAGCCACCAAGAATGTTTATAGGGGTATAGGAATATAGTTAACAGAGTGCTA ATCTCTCCTCAAATGTCCTTTTGGAATGCTTCCCCCAAAATTGGGAAGTTGGTAGGAGCTTTTCTTTACTTTGAATTTCTTTACTTGGAC AGAACGATTCTGCCTTAAAGACACGCTTTGCAGCTCTGATAAAGAACATCCCTGTTTAGTCTCTTGAGTTTTACAGGCCACAAAATGTCC GTCTCAGAGGGATCTGTCTCAGCTTTTCTTATTTTTGCTTCTCTCCGTTTTCAAAATTAATCATCTTGTTCTCTGTATAAGAAAATTTGA GAAGCTGTGGACAATTTAATAGTCTGATCTGGCAACAGCGATTTTTGTTTGGAAATATTTTGTGTTTTCTTTGAGGAGGATATAATTACT GATATCCTAGGATGTGAAATTTTTGAGTGACAGTATGCACATTTTAAAGAAAATTATGATTAATCTGTATAATGTTTTTTGGTCTGTAAA AATTATAAAAAATAAAATCATTTATCTTTGGTTGTAACTGTTTAAAAACCAAATTATAGGGATATCACACTATCTTGTAAAGTGTTTCAG CTGTTAAAGTTGCTGTAGGTTTTTATGCCTGATGTCATTTAATTTATTTGACATTGAACTTCATTAATAATCAGAGATGGTCAGTGAAAG CGCTTCCTCTTTAACTCTTTCTTGCTTAACCTTGGAAGGTTGACTCAACTCCTAGGTGTCTATGGGAAACTCTGGGCTAGGAACGTGCTA TAAAGACACTGAGCTAGTTCAGACATGGCCATGCTGCTGTAGCCTCCTGGGAAAGAAGGGCGGCAGAGAGACCAGCCCGCCTGTTGGCTT GCAGGGGTAATGAGCCTTGGCTTGAAAAAATTGTTGGCCTCCAGAGAGCACGGGGCTGTGGTTTCAGAATCAGTGATGGGTGCCGCACAT CAAGACGGGAATCAAGCAAGACCAAGGCCCTGTGGACTGAGCAGCGTGGAGGGCGAACGGCTGCAGGCTCCAGACTTCACCACAGGGTGG CCAACAGTGGCATCGGGACCAAATAAAGATGTCTAACAGCTTCCTGGGAGCAGGAGGAGGCAGGATTCTGGTTGCCATGAAAAACATCTC TCTCCCTCTCCATCACTCCCCATGCTGCAGTGCACAGGTGGGTTGCAGAGGCAGGCTGCATCCCGGAATCATGTTGTCCCACTGCCTATT AATAGAACAAGTGAAGGGCAGAATGCTGGAACACACCAGACATAGAGGGAGGGAGGTCCTGCCAGATGTGTCTACACAACTGTCTACATA GCATGACAGTAGCAGTGGATTCGGGACCCACCTGTACATGTTTCCAAAGCTCCTTCCTGCACACTCGGGACCTCAGCTCCAAGGCGTGAC TCATTTCTCAGTCTCACCATCCTTTGTTGGCTCAGACATCGCATGCCTCTGCCCCACTGGGGTTGTGTGCCTGCGTCTCTCACTTCTTTG AGGTTGGGGAAAGCCTAGTCCAGAAAATGAAAACCCATAGACCAGCCTAACTTCCTTTCAACCAAGTGACGGCCTCCTGGTTCCTCTCAG TTCATCATCAAAATCAGTGTGTACATGTCATACAAGCCAAGAGTGTTCATGTCCTCGTTCCTTTCAAATGAAGGTGATATATACTTTTTC ACTGAGTTTTTATTCCTGAAATTCTTTCTTCTGGAGCAGGAAGCAAATGTCCTGGAATCGTAGACTTTTACAGTCAGAAGGGTCATTCAC GTTCATCTAGTGCCCCTCTCACTCTGCAGGGATCCTCCTGCCTCTCCTCTGCCCCTGTCCAGTGCCTGGTGGTCCAGCCTGTGATGGGCA GGCCTAGGCTGCCATCCGCAGGCTCTGTAGTTCTGCTTTCTATTGAACCAAGATGTTTCTACGTTGCCTATTGGTCGTGGTTCTGTCCAG AGCAGTTCAGGCTGGGGCTGTTCACTTGCCCCTCCTTGAGGCAGACCTTTAGATATTTTCAGTTTTCATCACATGTCTAACACCACTTCC ACCCCACCCCTCACCTCTTAGGCTAAATCCAAGCTAAATCCCCCAATGTCTTTTTTTTTTTTTTTTTTTTGAGACGAGTCTCATCTGTCA CCCAGGCTGGAGTGCAATGGCATGGTCTCGGCTCACTGCAACCTCCGCCTCCTGGGTTCAAGCTATTCTGCCTCAGCCTCCCAAGGAGCC AGGACTACAGGTGCATGCCACCACGCCCGGCTAATTTTTGTATTTTTTAGTAGAGACAGGGTTTCACCCAGCCATTGAGACAAGCTGGTT TCAAACTCCTGACCTTGTGGTCCGCCCGCCCCGGCCTCCCAGAGTGCTGGGATTACAGGCGTGAGCCACCGCGCCCATCTCCCCTGCAAT GTCTTTAGTTAGACCTTTTCCACCATCATGTCTAACTGGGCTACGGTTTGGGGAAAGTGTCCAAATTAGTCCGTGTTATCCTAAAAGGGG TGTGCCCCGGATTAGCAGGGCCAGGGCTAGGGTGAGACAAATGAGGCACCTGGGGCATACATTTAAGTTGGTGCTTGCTTGCAGGTGCCA AGAGAGTGCTTCCTTGGGTTTACCCCCGTGGTGCCTCCTTTACCTCATTCTGGCCCCAGCCCTGGGGTTAGAGTCGCACCAGTGTGGTCC AAGTGGCATAATTATCTCCCTAAATGCTTGGGCAGCATCAGCTTTCAGTAGCTGTGCCCCATGGGAGGCACATTAAGCTAGTGGCAAGTT GAGACTGCAGACCTCAGCTTAATATCAGTTGTTGCCCAAGACAGATCTCACCCCACATCTTCATGACAGGCCTAACAACAAGGCACTTTG CCCTTAATCCTCTACTACTGCCTGCTCTTCATTTTGGGCCAACTGTACAGCTCATTTTGAGATAGTAGCTGATCATTTTTCTGATCAGTT AACTTTGTCTTATTAAGCAAAATGGAGAATATAATGTTGGGAAATAAGTGTGTTGATTAAAAGAAAGTATCCCCTTCTACCATCTTCCAT TTGTGTCTGGGTTGTGCTGGGTAAAGTTCTAGACTTACTAACGCAGACTTCATTTTGGTCCGGTTTCCACAGCATGCCTCGGGCATCAGT GTCCAGGAGTAGCTGTATTTGAGGTTTCCTTCACTCTGGTAGGTTCCTGATTCCTGATGAAAATAACTTGAAAAAAAAATAATTATACTA CTGATCCTCTTTTGGGATAATGAAATTGCGAAGGAATGTTGTTGATTATAACTTTTATTTTTTAATGTACAGATGTACTGTCTCTCATTG AGCACTGATAGAATTTATTTTTCTTTCAATAGTTTAAAATCACTTATGTGGAGACACATACTTAAGTGTGTTCAACTCGTTTTCTTCCCA CATATCTAGTGTGACCTTTAAAAACCACAACTTTATTTTGGACATTAAATGTGCAATATTCACTACTTATTCATTGTTCCACATTTTTCA TACTTGTACAAAGGGTAAGTTTTTATATAATGGTGAGAAACAGGAAGAAATGACAACTGGTTAAGTAAAATTCTGCAAATAAACTAGATT |
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FusionGenePPI for AMD1_EPG5 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| AMD1 | AMD1, ELAVL1, RTBDN, DOK3, POLR2M, DNASE2B, PRELP, BMP15, KPTN, CLEC11A, ASTL, BMP7, NYX, ADCYAP1, HSPB1, MED4, SSX2, DKKL1, POP4, FBXO4, MISP, SHC4, HDAC11, SHC1, SNX21, PTH2, CCDC120, POMC, GLTP, TCF25 | EPG5 | TP53 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for AMD1_EPG5 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
| Hgene | AMD1 | P17707 | DB03754 | Tromethamine | S-adenosylmethionine decarboxylase proenzyme | small molecule | approved |
| Hgene | AMD1 | P17707 | DB00118 | Ademetionine | S-adenosylmethionine decarboxylase proenzyme | small molecule | approved|investigational|nutraceutical |
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RelatedDiseases for AMD1_EPG5 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Tgene | EPG5 | C0021051 | Immunologic Deficiency Syndromes | 1 | CTD_human |
| Tgene | EPG5 | C0162835 | Hypopigmentation disorder | 1 | CTD_human |
| Tgene | EPG5 | C0878544 | Cardiomyopathies | 1 | CTD_human |
| Tgene | EPG5 | C1855772 | Absent corpus callosum cataract immunodeficiency | 1 | CTD_human;ORPHANET;UNIPROT |
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