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Fusion gene ID: 15514 |
FusionGeneSummary for GSE1_GLYR1 |
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Fusion gene information | Fusion gene name: GSE1_GLYR1 | Fusion gene ID: 15514 | Hgene | Tgene | Gene symbol | GSE1 | GLYR1 | Gene ID | 23199 | 84656 |
Gene name | Gse1 coiled-coil protein | glyoxylate reductase 1 homolog | |
Synonyms | CRHSP24|KIAA0182 | BM045|HIBDL|N-PAC|NP60 | |
Cytomap | 16q24.1 | 16p13.3 | |
Type of gene | protein-coding | protein-coding | |
Description | genetic suppressor element 1CTC-786C10.1Gse1 coiled-coil protein homolog | putative oxidoreductase GLYR13-hydroxyisobutyrate dehydrogenase-like proteincytokine-like nuclear factor n-pacnuclear protein 60 kDanuclear protein 60kDanuclear protein NP60nuclear protein of 60 kDa | |
Modification date | 20180519 | 20180523 | |
UniProtAcc | Q14687 | Q49A26 | |
Ensembl transtripts involved in fusion gene | ENST00000405402, ENST00000253458, ENST00000393243, ENST00000471070, | ENST00000436648, ENST00000321919, ENST00000381983, ENST00000591451, ENST00000586901, | |
Fusion gene scores | * DoF score | 13 X 9 X 7=819 | 5 X 3 X 3=45 |
# samples | 13 | 5 | |
** MAII score | log2(13/819*10)=-2.65535182861255 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(5/45*10)=0.15200309344505 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
Context | PubMed: GSE1 [Title/Abstract] AND GLYR1 [Title/Abstract] AND fusion [Title/Abstract] | ||
Functional or gene categories assigned by FusionGDB annotation |
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
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Partner | Gene | GO ID | GO term | PubMed ID |
![]() (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
TCGA | LD | LUAD | TCGA-55-6968-01A | GSE1 | chr16 | 85589969 | + | GLYR1 | chr16 | 4855311 | - |
* LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
![]() * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
intron-3CDS | ENST00000405402 | ENST00000436648 | GSE1 | chr16 | 85589969 | + | GLYR1 | chr16 | 4855311 | - |
intron-3CDS | ENST00000405402 | ENST00000321919 | GSE1 | chr16 | 85589969 | + | GLYR1 | chr16 | 4855311 | - |
intron-3CDS | ENST00000405402 | ENST00000381983 | GSE1 | chr16 | 85589969 | + | GLYR1 | chr16 | 4855311 | - |
intron-3CDS | ENST00000405402 | ENST00000591451 | GSE1 | chr16 | 85589969 | + | GLYR1 | chr16 | 4855311 | - |
intron-intron | ENST00000405402 | ENST00000586901 | GSE1 | chr16 | 85589969 | + | GLYR1 | chr16 | 4855311 | - |
intron-3CDS | ENST00000253458 | ENST00000436648 | GSE1 | chr16 | 85589969 | + | GLYR1 | chr16 | 4855311 | - |
intron-3CDS | ENST00000253458 | ENST00000321919 | GSE1 | chr16 | 85589969 | + | GLYR1 | chr16 | 4855311 | - |
intron-3CDS | ENST00000253458 | ENST00000381983 | GSE1 | chr16 | 85589969 | + | GLYR1 | chr16 | 4855311 | - |
intron-3CDS | ENST00000253458 | ENST00000591451 | GSE1 | chr16 | 85589969 | + | GLYR1 | chr16 | 4855311 | - |
intron-intron | ENST00000253458 | ENST00000586901 | GSE1 | chr16 | 85589969 | + | GLYR1 | chr16 | 4855311 | - |
intron-3CDS | ENST00000393243 | ENST00000436648 | GSE1 | chr16 | 85589969 | + | GLYR1 | chr16 | 4855311 | - |
intron-3CDS | ENST00000393243 | ENST00000321919 | GSE1 | chr16 | 85589969 | + | GLYR1 | chr16 | 4855311 | - |
intron-3CDS | ENST00000393243 | ENST00000381983 | GSE1 | chr16 | 85589969 | + | GLYR1 | chr16 | 4855311 | - |
intron-3CDS | ENST00000393243 | ENST00000591451 | GSE1 | chr16 | 85589969 | + | GLYR1 | chr16 | 4855311 | - |
intron-intron | ENST00000393243 | ENST00000586901 | GSE1 | chr16 | 85589969 | + | GLYR1 | chr16 | 4855311 | - |
intron-3CDS | ENST00000471070 | ENST00000436648 | GSE1 | chr16 | 85589969 | + | GLYR1 | chr16 | 4855311 | - |
intron-3CDS | ENST00000471070 | ENST00000321919 | GSE1 | chr16 | 85589969 | + | GLYR1 | chr16 | 4855311 | - |
intron-3CDS | ENST00000471070 | ENST00000381983 | GSE1 | chr16 | 85589969 | + | GLYR1 | chr16 | 4855311 | - |
intron-3CDS | ENST00000471070 | ENST00000591451 | GSE1 | chr16 | 85589969 | + | GLYR1 | chr16 | 4855311 | - |
intron-intron | ENST00000471070 | ENST00000586901 | GSE1 | chr16 | 85589969 | + | GLYR1 | chr16 | 4855311 | - |
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FusionProtFeatures for GSE1_GLYR1 |
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Hgene | Tgene |
GSE1 | GLYR1 |
![]() * Minus value of BPloci means that the break pointn is located before the CDS. |
- In-frame and retained protein feature among the 13 regional features. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
- In-frame and not-retained protein feature among the 13 regional features. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
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FusionGeneSequence for GSE1_GLYR1 |
![]() (nt: nucleotides, aa: amino acids) |
* Fusion amino acid sequences. |
* Fusion transcript sequences (only coding sequence (CDS) region). |
* Fusion transcript sequences (Full-length transcript). |
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FusionGenePPI for GSE1_GLYR1 |
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Hgene | Hgene's interactors | Tgene | Tgene's interactors |
GSE1 | NUDT18, RBPMS, RCOR3, HDAC2, KDM1A, RBM48, XRCC6, NR2E1, CDC5L, CEP63, TNIK, ELAVL1, TCF3, FUS, HDAC1, MTA3, EXOSC6, DGCR6, RUNX1T1, GOLGA2, TRIP6, RALBP1, GSE1, C1orf94, TEKT4, C6orf165, SNAI1, HMG20B, FGF1, DOK4, NTRK1, SRPK2, NINL, MAPK3, HMG20A, TCF4, EYA2, LLGL2, HAO2, FAM136A, NR3C1, AR, TRIM25 | GLYR1 | ELAVL1, SIRT7, DHX9, ESR1, GEMIN4, KDM1A, WHSC1L1, CCNC, FHL2, EIF1AD, C6orf165, HIST3H3, SUZ12, EED, RNF2, RPL8, NPM1, MAGEA1, PRR11, ILF2, NEFH, BLK, HAL, KDM1B, LCP1, SERPINA12, CAPNS2, FNTB, ALOXE3, DDX18, FBL, NOP56, NOP58, RCC1, RFC1, TOP2A, TOP2B, NOC2L, IFI16, MED4, HIST1H3E, HNRNPU, FOXL2, CDC14B, WDR46, ZNF2, RPL37A, GLTSCR2, RPL28, CNBP, DGCR8, HIST1H1E, RPL30, ZC3HAV1, RRP8, STAU1, ZCRB1, H2AFY2, PRDM5, PPAN, RPL18A, FGF8, GPATCH4, PDGFB, CDX1, ECM1, PLEKHO1, RRS1, RSBN1, RBM4, RBM34, KNOP1, HIST1H3A |
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Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
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Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for GSE1_GLYR1 |
![]() (DrugBank Version 5.1.0 2018-04-02) |
Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for GSE1_GLYR1 |
![]() (DisGeNet 4.0) |
Partner | Gene | Disease ID | Disease name | # pubmeds | Source |