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Fusion gene ID: 15500 |
FusionGeneSummary for GRTP1_SPATC1L |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: GRTP1_SPATC1L | Fusion gene ID: 15500 | Hgene | Tgene | Gene symbol | GRTP1 | SPATC1L | Gene ID | 79774 | 84221 |
| Gene name | growth hormone regulated TBC protein 1 | spermatogenesis and centriole associated 1 like | |
| Synonyms | TBC1D6 | C21orf56 | |
| Cytomap | 13q34 | 21q22.3 | |
| Type of gene | protein-coding | protein-coding | |
| Description | growth hormone-regulated TBC protein 1TBC1 domain family member 6 | speriolin-like proteinspermatogenesis and centriole-associated protein 1-like protein | |
| Modification date | 20180523 | 20180523 | |
| UniProtAcc | Q5TC63 | Q9H0A9 | |
| Ensembl transtripts involved in fusion gene | ENST00000375431, ENST00000326039, ENST00000375430, ENST00000476439, | ENST00000330205, ENST00000291672, | |
| Fusion gene scores | * DoF score | 5 X 4 X 4=80 | 3 X 2 X 2=12 |
| # samples | 5 | 3 | |
| ** MAII score | log2(5/80*10)=-0.678071905112638 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(3/12*10)=1.32192809488736 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
| Context | PubMed: GRTP1 [Title/Abstract] AND SPATC1L [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | SARC | TCGA-IF-A4AK-01A | GRTP1 | chr13 | 114009638 | - | SPATC1L | chr21 | 47581981 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000375431 | ENST00000330205 | GRTP1 | chr13 | 114009638 | - | SPATC1L | chr21 | 47581981 | - |
| In-frame | ENST00000375431 | ENST00000291672 | GRTP1 | chr13 | 114009638 | - | SPATC1L | chr21 | 47581981 | - |
| Frame-shift | ENST00000326039 | ENST00000330205 | GRTP1 | chr13 | 114009638 | - | SPATC1L | chr21 | 47581981 | - |
| Frame-shift | ENST00000326039 | ENST00000291672 | GRTP1 | chr13 | 114009638 | - | SPATC1L | chr21 | 47581981 | - |
| In-frame | ENST00000375430 | ENST00000330205 | GRTP1 | chr13 | 114009638 | - | SPATC1L | chr21 | 47581981 | - |
| In-frame | ENST00000375430 | ENST00000291672 | GRTP1 | chr13 | 114009638 | - | SPATC1L | chr21 | 47581981 | - |
| intron-3CDS | ENST00000476439 | ENST00000330205 | GRTP1 | chr13 | 114009638 | - | SPATC1L | chr21 | 47581981 | - |
| intron-3CDS | ENST00000476439 | ENST00000291672 | GRTP1 | chr13 | 114009638 | - | SPATC1L | chr21 | 47581981 | - |
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FusionProtFeatures for GRTP1_SPATC1L |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| GRTP1 | SPATC1L |
| May act as a GTPase-activating protein for Rab familyprotein(s). |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | >SPATC1L | chr13:114009638 | chr21:47581981 | ENST00000291672 | - | 2 | 5 | 320_323 | 181 | 341 | Compositional bias | Note=Poly-Leu |
| Tgene | >SPATC1L | chr13:114009638 | chr21:47581981 | ENST00000330205 | - | 1 | 4 | 320_323 | 27 | 187 | Compositional bias | Note=Poly-Leu |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >GRTP1 | chr13:114009638 | chr21:47581981 | ENST00000326039 | - | 1 | 5 | 68_258 | 35 | 267 | Domain | Rab-GAP TBC |
| Hgene | >GRTP1 | chr13:114009638 | chr21:47581981 | ENST00000375431 | - | 3 | 8 | 68_258 | 113 | 337 | Domain | Rab-GAP TBC |
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FusionGeneSequence for GRTP1_SPATC1L |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_GRTP1_ENST00000375431_chr13_114009638_-_SPATC1L_ENST00000330205_chr21_47581981_-_273aa MQPAERSRVPRIDPYGFERPEDFDDAAYEKFFSSYLVTLTRRAIKWSRLLQGGGVPRSRTVKRYVRKGVPLEHRARVWMVLSGAQAQMDQ NPGYYHQLLQGERNPRLEDAIRTEIQSFAGAEKDARVVGEIAFQLDRRILAYVFPGVTRLYGFTVANIPEKIEQTSTKSLDGSVDERKLR ELTQRYLALSARLEKLGYSRDVHPAFSEFLINTYGILKQRPDLRANPLHSSPAALRKLVIDVVPPKFLGDSLLLLNCLCELSKEDGKPLF >In-frame_GRTP1_ENST00000375431_chr13_114009638_-_SPATC1L_ENST00000291672_chr21_47581981_-_273aa MQPAERSRVPRIDPYGFERPEDFDDAAYEKFFSSYLVTLTRRAIKWSRLLQGGGVPRSRTVKRYVRKGVPLEHRARVWMVLSGAQAQMDQ NPGYYHQLLQGERNPRLEDAIRTEIQSFAGAEKDARVVGEIAFQLDRRILAYVFPGVTRLYGFTVANIPEKIEQTSTKSLDGSVDERKLR ELTQRYLALSARLEKLGYSRDVHPAFSEFLINTYGILKQRPDLRANPLHSSPAALRKLVIDVVPPKFLGDSLLLLNCLCELSKEDGKPLF >In-frame_GRTP1_ENST00000375430_chr13_114009638_-_SPATC1L_ENST00000330205_chr21_47581981_-_273aa MQPAERSRVPRIDPYGFERPEDFDDAAYEKFFSSYLVTLTRRAIKWSRLLQGGGVPRSRTVKRYVRKGVPLEHRARVWMVLSGAQAQMDQ NPGYYHQLLQGERNPRLEDAIRTEIQSFAGAEKDARVVGEIAFQLDRRILAYVFPGVTRLYGFTVANIPEKIEQTSTKSLDGSVDERKLR ELTQRYLALSARLEKLGYSRDVHPAFSEFLINTYGILKQRPDLRANPLHSSPAALRKLVIDVVPPKFLGDSLLLLNCLCELSKEDGKPLF >In-frame_GRTP1_ENST00000375430_chr13_114009638_-_SPATC1L_ENST00000291672_chr21_47581981_-_273aa MQPAERSRVPRIDPYGFERPEDFDDAAYEKFFSSYLVTLTRRAIKWSRLLQGGGVPRSRTVKRYVRKGVPLEHRARVWMVLSGAQAQMDQ NPGYYHQLLQGERNPRLEDAIRTEIQSFAGAEKDARVVGEIAFQLDRRILAYVFPGVTRLYGFTVANIPEKIEQTSTKSLDGSVDERKLR ELTQRYLALSARLEKLGYSRDVHPAFSEFLINTYGILKQRPDLRANPLHSSPAALRKLVIDVVPPKFLGDSLLLLNCLCELSKEDGKPLF |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_GRTP1_ENST00000375431_chr13_114009638_-_SPATC1L_ENST00000330205_chr21_47581981_-_819nt ATGCAGCCCGCCGAGCGCTCGCGGGTCCCCAGGATCGACCCGTACGGATTCGAGCGGCCTGAGGACTTCGACGACGCCGCCTACGAGAAG TTTTTCTCCAGCTACCTGGTCACGCTCACCCGCAGGGCGATCAAATGGTCCCGGCTGCTGCAGGGCGGGGGCGTCCCCAGGAGCCGGACA GTGAAGCGCTATGTCCGGAAAGGGGTCCCGCTGGAGCACCGTGCCCGCGTCTGGATGGTGCTGAGTGGGGCCCAGGCGCAGATGGACCAG AATCCCGGCTACTACCACCAGCTTCTCCAGGGAGAGAGAAACCCCAGGCTGGAGGACGCCATCAGGACAGAGATCCAGAGCTTCGCGGGC GCCGAGAAGGACGCGCGCGTGGTGGGCGAGATCGCCTTCCAGCTGGACCGCCGCATCCTGGCCTACGTGTTCCCGGGCGTGACGCGGCTC TACGGCTTCACGGTGGCCAACATCCCCGAGAAGATCGAGCAGACCTCCACCAAGTCTCTGGACGGCTCCGTGGACGAGAGGAAGCTGCGC GAGCTGACGCAGCGCTACCTGGCCCTGAGCGCGCGCCTGGAGAAGCTGGGCTACAGCCGCGACGTGCACCCGGCGTTCAGCGAGTTCCTC ATCAACACCTACGGAATCCTGAAGCAGCGGCCCGACCTGCGCGCCAACCCCCTGCACAGCAGCCCGGCCGCGCTGCGCAAGCTGGTCATC GACGTGGTGCCCCCCAAGTTCCTGGGCGACTCGCTGCTGCTGCTCAACTGCCTGTGCGAGCTCTCCAAGGAGGACGGCAAGCCCCTCTTC >In-frame_GRTP1_ENST00000375431_chr13_114009638_-_SPATC1L_ENST00000291672_chr21_47581981_-_819nt ATGCAGCCCGCCGAGCGCTCGCGGGTCCCCAGGATCGACCCGTACGGATTCGAGCGGCCTGAGGACTTCGACGACGCCGCCTACGAGAAG TTTTTCTCCAGCTACCTGGTCACGCTCACCCGCAGGGCGATCAAATGGTCCCGGCTGCTGCAGGGCGGGGGCGTCCCCAGGAGCCGGACA GTGAAGCGCTATGTCCGGAAAGGGGTCCCGCTGGAGCACCGTGCCCGCGTCTGGATGGTGCTGAGTGGGGCCCAGGCGCAGATGGACCAG AATCCCGGCTACTACCACCAGCTTCTCCAGGGAGAGAGAAACCCCAGGCTGGAGGACGCCATCAGGACAGAGATCCAGAGCTTCGCGGGC GCCGAGAAGGACGCGCGCGTGGTGGGCGAGATCGCCTTCCAGCTGGACCGCCGCATCCTGGCCTACGTGTTCCCGGGCGTGACGCGGCTC TACGGCTTCACGGTGGCCAACATCCCCGAGAAGATCGAGCAGACCTCCACCAAGTCTCTGGACGGCTCCGTGGACGAGAGGAAGCTGCGC GAGCTGACGCAGCGCTACCTGGCCCTGAGCGCGCGCCTGGAGAAGCTGGGCTACAGCCGCGACGTGCACCCGGCGTTCAGCGAGTTCCTC ATCAACACCTACGGAATCCTGAAGCAGCGGCCCGACCTGCGCGCCAACCCCCTGCACAGCAGCCCGGCCGCGCTGCGCAAGCTGGTCATC GACGTGGTGCCCCCCAAGTTCCTGGGCGACTCGCTGCTGCTGCTCAACTGCCTGTGCGAGCTCTCCAAGGAGGACGGCAAGCCCCTCTTC >In-frame_GRTP1_ENST00000375430_chr13_114009638_-_SPATC1L_ENST00000330205_chr21_47581981_-_819nt ATGCAGCCCGCCGAGCGCTCGCGGGTCCCCAGGATCGACCCGTACGGATTCGAGCGGCCTGAGGACTTCGACGACGCCGCCTACGAGAAG TTTTTCTCCAGCTACCTGGTCACGCTCACCCGCAGGGCGATCAAATGGTCCCGGCTGCTGCAGGGCGGGGGCGTCCCCAGGAGCCGGACA GTGAAGCGCTATGTCCGGAAAGGGGTCCCGCTGGAGCACCGTGCCCGCGTCTGGATGGTGCTGAGTGGGGCCCAGGCGCAGATGGACCAG AATCCCGGCTACTACCACCAGCTTCTCCAGGGAGAGAGAAACCCCAGGCTGGAGGACGCCATCAGGACAGAGATCCAGAGCTTCGCGGGC GCCGAGAAGGACGCGCGCGTGGTGGGCGAGATCGCCTTCCAGCTGGACCGCCGCATCCTGGCCTACGTGTTCCCGGGCGTGACGCGGCTC TACGGCTTCACGGTGGCCAACATCCCCGAGAAGATCGAGCAGACCTCCACCAAGTCTCTGGACGGCTCCGTGGACGAGAGGAAGCTGCGC GAGCTGACGCAGCGCTACCTGGCCCTGAGCGCGCGCCTGGAGAAGCTGGGCTACAGCCGCGACGTGCACCCGGCGTTCAGCGAGTTCCTC ATCAACACCTACGGAATCCTGAAGCAGCGGCCCGACCTGCGCGCCAACCCCCTGCACAGCAGCCCGGCCGCGCTGCGCAAGCTGGTCATC GACGTGGTGCCCCCCAAGTTCCTGGGCGACTCGCTGCTGCTGCTCAACTGCCTGTGCGAGCTCTCCAAGGAGGACGGCAAGCCCCTCTTC >In-frame_GRTP1_ENST00000375430_chr13_114009638_-_SPATC1L_ENST00000291672_chr21_47581981_-_819nt ATGCAGCCCGCCGAGCGCTCGCGGGTCCCCAGGATCGACCCGTACGGATTCGAGCGGCCTGAGGACTTCGACGACGCCGCCTACGAGAAG TTTTTCTCCAGCTACCTGGTCACGCTCACCCGCAGGGCGATCAAATGGTCCCGGCTGCTGCAGGGCGGGGGCGTCCCCAGGAGCCGGACA GTGAAGCGCTATGTCCGGAAAGGGGTCCCGCTGGAGCACCGTGCCCGCGTCTGGATGGTGCTGAGTGGGGCCCAGGCGCAGATGGACCAG AATCCCGGCTACTACCACCAGCTTCTCCAGGGAGAGAGAAACCCCAGGCTGGAGGACGCCATCAGGACAGAGATCCAGAGCTTCGCGGGC GCCGAGAAGGACGCGCGCGTGGTGGGCGAGATCGCCTTCCAGCTGGACCGCCGCATCCTGGCCTACGTGTTCCCGGGCGTGACGCGGCTC TACGGCTTCACGGTGGCCAACATCCCCGAGAAGATCGAGCAGACCTCCACCAAGTCTCTGGACGGCTCCGTGGACGAGAGGAAGCTGCGC GAGCTGACGCAGCGCTACCTGGCCCTGAGCGCGCGCCTGGAGAAGCTGGGCTACAGCCGCGACGTGCACCCGGCGTTCAGCGAGTTCCTC ATCAACACCTACGGAATCCTGAAGCAGCGGCCCGACCTGCGCGCCAACCCCCTGCACAGCAGCCCGGCCGCGCTGCGCAAGCTGGTCATC GACGTGGTGCCCCCCAAGTTCCTGGGCGACTCGCTGCTGCTGCTCAACTGCCTGTGCGAGCTCTCCAAGGAGGACGGCAAGCCCCTCTTC |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_GRTP1_ENST00000375431_chr13_114009638_-_SPATC1L_ENST00000330205_chr21_47581981_-_1125nt GGACTTAAGCGCCCCGGAGCCGGGAGGCGAACTTGGGACCCGCTGGCCTCGCTCGGTGCGCGCCTCCCTCCCCGCATGCAGCCCGCCGAG CGCTCGCGGGTCCCCAGGATCGACCCGTACGGATTCGAGCGGCCTGAGGACTTCGACGACGCCGCCTACGAGAAGTTTTTCTCCAGCTAC CTGGTCACGCTCACCCGCAGGGCGATCAAATGGTCCCGGCTGCTGCAGGGCGGGGGCGTCCCCAGGAGCCGGACAGTGAAGCGCTATGTC CGGAAAGGGGTCCCGCTGGAGCACCGTGCCCGCGTCTGGATGGTGCTGAGTGGGGCCCAGGCGCAGATGGACCAGAATCCCGGCTACTAC CACCAGCTTCTCCAGGGAGAGAGAAACCCCAGGCTGGAGGACGCCATCAGGACAGAGATCCAGAGCTTCGCGGGCGCCGAGAAGGACGCG CGCGTGGTGGGCGAGATCGCCTTCCAGCTGGACCGCCGCATCCTGGCCTACGTGTTCCCGGGCGTGACGCGGCTCTACGGCTTCACGGTG GCCAACATCCCCGAGAAGATCGAGCAGACCTCCACCAAGTCTCTGGACGGCTCCGTGGACGAGAGGAAGCTGCGCGAGCTGACGCAGCGC TACCTGGCCCTGAGCGCGCGCCTGGAGAAGCTGGGCTACAGCCGCGACGTGCACCCGGCGTTCAGCGAGTTCCTCATCAACACCTACGGA ATCCTGAAGCAGCGGCCCGACCTGCGCGCCAACCCCCTGCACAGCAGCCCGGCCGCGCTGCGCAAGCTGGTCATCGACGTGGTGCCCCCC AAGTTCCTGGGCGACTCGCTGCTGCTGCTCAACTGCCTGTGCGAGCTCTCCAAGGAGGACGGCAAGCCCCTCTTCGCCTGGTGAGCCGCC CCGCGCCCGCCGCCTTGCCTGCAGTAAACGCGTTTGTTCCAACCCGGGGCCGCGGTGCCTCCTGCGCGTCCCCCCGGAGGGGAAAGGGCC GCGTCCCCCGCGCGCGAGGCCAGAGAAGGCCCCGCTCCCACCGGTGCTGGGCCCCGACCGCAGCCCGCCGCTGCCCGCACCTGCGGAGTG >In-frame_GRTP1_ENST00000375431_chr13_114009638_-_SPATC1L_ENST00000291672_chr21_47581981_-_1112nt GGACTTAAGCGCCCCGGAGCCGGGAGGCGAACTTGGGACCCGCTGGCCTCGCTCGGTGCGCGCCTCCCTCCCCGCATGCAGCCCGCCGAG CGCTCGCGGGTCCCCAGGATCGACCCGTACGGATTCGAGCGGCCTGAGGACTTCGACGACGCCGCCTACGAGAAGTTTTTCTCCAGCTAC CTGGTCACGCTCACCCGCAGGGCGATCAAATGGTCCCGGCTGCTGCAGGGCGGGGGCGTCCCCAGGAGCCGGACAGTGAAGCGCTATGTC CGGAAAGGGGTCCCGCTGGAGCACCGTGCCCGCGTCTGGATGGTGCTGAGTGGGGCCCAGGCGCAGATGGACCAGAATCCCGGCTACTAC CACCAGCTTCTCCAGGGAGAGAGAAACCCCAGGCTGGAGGACGCCATCAGGACAGAGATCCAGAGCTTCGCGGGCGCCGAGAAGGACGCG CGCGTGGTGGGCGAGATCGCCTTCCAGCTGGACCGCCGCATCCTGGCCTACGTGTTCCCGGGCGTGACGCGGCTCTACGGCTTCACGGTG GCCAACATCCCCGAGAAGATCGAGCAGACCTCCACCAAGTCTCTGGACGGCTCCGTGGACGAGAGGAAGCTGCGCGAGCTGACGCAGCGC TACCTGGCCCTGAGCGCGCGCCTGGAGAAGCTGGGCTACAGCCGCGACGTGCACCCGGCGTTCAGCGAGTTCCTCATCAACACCTACGGA ATCCTGAAGCAGCGGCCCGACCTGCGCGCCAACCCCCTGCACAGCAGCCCGGCCGCGCTGCGCAAGCTGGTCATCGACGTGGTGCCCCCC AAGTTCCTGGGCGACTCGCTGCTGCTGCTCAACTGCCTGTGCGAGCTCTCCAAGGAGGACGGCAAGCCCCTCTTCGCCTGGTGAGCCGCC CCGCGCCCGCCGCCTTGCCTGCAGTAAACGCGTTTGTTCCAACCCGGGGCCGCGGTGCCTCCTGCGCGTCCCCCCGGAGGGGAAAGGGCC GCGTCCCCCGCGCGCGAGGCCAGAGAAGGCCCCGCTCCCACCGGTGCTGGGCCCCGACCGCAGCCCGCCGCTGCCCGCACCTGCGGAGTG >In-frame_GRTP1_ENST00000375430_chr13_114009638_-_SPATC1L_ENST00000330205_chr21_47581981_-_1097nt GAACTTGGGACCCGCTGGCCTCGCTCGGTGCGCGCCTCCCTCCCCGCATGCAGCCCGCCGAGCGCTCGCGGGTCCCCAGGATCGACCCGT ACGGATTCGAGCGGCCTGAGGACTTCGACGACGCCGCCTACGAGAAGTTTTTCTCCAGCTACCTGGTCACGCTCACCCGCAGGGCGATCA AATGGTCCCGGCTGCTGCAGGGCGGGGGCGTCCCCAGGAGCCGGACAGTGAAGCGCTATGTCCGGAAAGGGGTCCCGCTGGAGCACCGTG CCCGCGTCTGGATGGTGCTGAGTGGGGCCCAGGCGCAGATGGACCAGAATCCCGGCTACTACCACCAGCTTCTCCAGGGAGAGAGAAACC CCAGGCTGGAGGACGCCATCAGGACAGAGATCCAGAGCTTCGCGGGCGCCGAGAAGGACGCGCGCGTGGTGGGCGAGATCGCCTTCCAGC TGGACCGCCGCATCCTGGCCTACGTGTTCCCGGGCGTGACGCGGCTCTACGGCTTCACGGTGGCCAACATCCCCGAGAAGATCGAGCAGA CCTCCACCAAGTCTCTGGACGGCTCCGTGGACGAGAGGAAGCTGCGCGAGCTGACGCAGCGCTACCTGGCCCTGAGCGCGCGCCTGGAGA AGCTGGGCTACAGCCGCGACGTGCACCCGGCGTTCAGCGAGTTCCTCATCAACACCTACGGAATCCTGAAGCAGCGGCCCGACCTGCGCG CCAACCCCCTGCACAGCAGCCCGGCCGCGCTGCGCAAGCTGGTCATCGACGTGGTGCCCCCCAAGTTCCTGGGCGACTCGCTGCTGCTGC TCAACTGCCTGTGCGAGCTCTCCAAGGAGGACGGCAAGCCCCTCTTCGCCTGGTGAGCCGCCCCGCGCCCGCCGCCTTGCCTGCAGTAAA CGCGTTTGTTCCAACCCGGGGCCGCGGTGCCTCCTGCGCGTCCCCCCGGAGGGGAAAGGGCCGCGTCCCCCGCGCGCGAGGCCAGAGAAG GCCCCGCTCCCACCGGTGCTGGGCCCCGACCGCAGCCCGCCGCTGCCCGCACCTGCGGAGTGCTTCTCACCCCTCATTAAAATCATCCGT >In-frame_GRTP1_ENST00000375430_chr13_114009638_-_SPATC1L_ENST00000291672_chr21_47581981_-_1084nt GAACTTGGGACCCGCTGGCCTCGCTCGGTGCGCGCCTCCCTCCCCGCATGCAGCCCGCCGAGCGCTCGCGGGTCCCCAGGATCGACCCGT ACGGATTCGAGCGGCCTGAGGACTTCGACGACGCCGCCTACGAGAAGTTTTTCTCCAGCTACCTGGTCACGCTCACCCGCAGGGCGATCA AATGGTCCCGGCTGCTGCAGGGCGGGGGCGTCCCCAGGAGCCGGACAGTGAAGCGCTATGTCCGGAAAGGGGTCCCGCTGGAGCACCGTG CCCGCGTCTGGATGGTGCTGAGTGGGGCCCAGGCGCAGATGGACCAGAATCCCGGCTACTACCACCAGCTTCTCCAGGGAGAGAGAAACC CCAGGCTGGAGGACGCCATCAGGACAGAGATCCAGAGCTTCGCGGGCGCCGAGAAGGACGCGCGCGTGGTGGGCGAGATCGCCTTCCAGC TGGACCGCCGCATCCTGGCCTACGTGTTCCCGGGCGTGACGCGGCTCTACGGCTTCACGGTGGCCAACATCCCCGAGAAGATCGAGCAGA CCTCCACCAAGTCTCTGGACGGCTCCGTGGACGAGAGGAAGCTGCGCGAGCTGACGCAGCGCTACCTGGCCCTGAGCGCGCGCCTGGAGA AGCTGGGCTACAGCCGCGACGTGCACCCGGCGTTCAGCGAGTTCCTCATCAACACCTACGGAATCCTGAAGCAGCGGCCCGACCTGCGCG CCAACCCCCTGCACAGCAGCCCGGCCGCGCTGCGCAAGCTGGTCATCGACGTGGTGCCCCCCAAGTTCCTGGGCGACTCGCTGCTGCTGC TCAACTGCCTGTGCGAGCTCTCCAAGGAGGACGGCAAGCCCCTCTTCGCCTGGTGAGCCGCCCCGCGCCCGCCGCCTTGCCTGCAGTAAA CGCGTTTGTTCCAACCCGGGGCCGCGGTGCCTCCTGCGCGTCCCCCCGGAGGGGAAAGGGCCGCGTCCCCCGCGCGCGAGGCCAGAGAAG GCCCCGCTCCCACCGGTGCTGGGCCCCGACCGCAGCCCGCCGCTGCCCGCACCTGCGGAGTGCTTCTCACCCCTCATTAAAATCATCCGT |
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FusionGenePPI for GRTP1_SPATC1L |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| GRTP1 | NES, PCDHGC3, GJB7, FAM63A, UBB, ATP2A1 | SPATC1L | PARN, PPP1CC, PHC2, TRIM27, SIAH1, TCF4, PNMA1, ARL4A, IKZF1, ARMC7, LZTS2, FSD2, ASPDH, KRTAP5-9, EGFR |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for GRTP1_SPATC1L |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for GRTP1_SPATC1L |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
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