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Fusion gene ID: 15054 |
FusionGeneSummary for GOLGA7_SLC25A44 |
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Fusion gene information | Fusion gene name: GOLGA7_SLC25A44 | Fusion gene ID: 15054 | Hgene | Tgene | Gene symbol | GOLGA7 | SLC25A44 | Gene ID | 51125 | 9673 |
Gene name | golgin A7 | solute carrier family 25 member 44 | |
Synonyms | GCP16|GOLGA3AP1|GOLGA7A|HSPC041 | - | |
Cytomap | 8p11.21 | 1q22 | |
Type of gene | protein-coding | protein-coding | |
Description | golgin subfamily A member 7Golgi complex-associated protein of 16kDagolgi autoantigen, golgin subfamily a, 7golgi complex-associated protein of 16 kDa | solute carrier family 25 member 44 | |
Modification date | 20180523 | 20180522 | |
UniProtAcc | Q7Z5G4 | Q96H78 | |
Ensembl transtripts involved in fusion gene | ENST00000518270, ENST00000520817, ENST00000405786, ENST00000357743, ENST00000521417, | ENST00000359511, ENST00000423538, ENST00000469537, | |
Fusion gene scores | * DoF score | 3 X 3 X 2=18 | 3 X 3 X 3=27 |
# samples | 3 | 3 | |
** MAII score | log2(3/18*10)=0.736965594166206 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | log2(3/27*10)=0.15200309344505 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
Context | PubMed: GOLGA7 [Title/Abstract] AND SLC25A44 [Title/Abstract] AND fusion [Title/Abstract] | ||
Functional or gene categories assigned by FusionGDB annotation |
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
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Partner | Gene | GO ID | GO term | PubMed ID |
Hgene | GOLGA7 | GO:0018230 | peptidyl-L-cysteine S-palmitoylation | 16000296 |
Hgene | GOLGA7 | GO:0043001 | Golgi to plasma membrane protein transport | 14522980 |
Hgene | GOLGA7 | GO:0050821 | protein stabilization | 16000296 |
![]() (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
TCGA | LD | BRCA | TCGA-E9-A1N6-01A | GOLGA7 | chr8 | 41364640 | + | SLC25A44 | chr1 | 156169626 | + |
* LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
![]() * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
3UTR-5UTR | ENST00000518270 | ENST00000359511 | GOLGA7 | chr8 | 41364640 | + | SLC25A44 | chr1 | 156169626 | + |
3UTR-5UTR | ENST00000518270 | ENST00000423538 | GOLGA7 | chr8 | 41364640 | + | SLC25A44 | chr1 | 156169626 | + |
3UTR-3UTR | ENST00000518270 | ENST00000469537 | GOLGA7 | chr8 | 41364640 | + | SLC25A44 | chr1 | 156169626 | + |
3UTR-5UTR | ENST00000520817 | ENST00000359511 | GOLGA7 | chr8 | 41364640 | + | SLC25A44 | chr1 | 156169626 | + |
3UTR-5UTR | ENST00000520817 | ENST00000423538 | GOLGA7 | chr8 | 41364640 | + | SLC25A44 | chr1 | 156169626 | + |
3UTR-3UTR | ENST00000520817 | ENST00000469537 | GOLGA7 | chr8 | 41364640 | + | SLC25A44 | chr1 | 156169626 | + |
3UTR-5UTR | ENST00000405786 | ENST00000359511 | GOLGA7 | chr8 | 41364640 | + | SLC25A44 | chr1 | 156169626 | + |
3UTR-5UTR | ENST00000405786 | ENST00000423538 | GOLGA7 | chr8 | 41364640 | + | SLC25A44 | chr1 | 156169626 | + |
3UTR-3UTR | ENST00000405786 | ENST00000469537 | GOLGA7 | chr8 | 41364640 | + | SLC25A44 | chr1 | 156169626 | + |
3UTR-5UTR | ENST00000357743 | ENST00000359511 | GOLGA7 | chr8 | 41364640 | + | SLC25A44 | chr1 | 156169626 | + |
3UTR-5UTR | ENST00000357743 | ENST00000423538 | GOLGA7 | chr8 | 41364640 | + | SLC25A44 | chr1 | 156169626 | + |
3UTR-3UTR | ENST00000357743 | ENST00000469537 | GOLGA7 | chr8 | 41364640 | + | SLC25A44 | chr1 | 156169626 | + |
3UTR-5UTR | ENST00000521417 | ENST00000359511 | GOLGA7 | chr8 | 41364640 | + | SLC25A44 | chr1 | 156169626 | + |
3UTR-5UTR | ENST00000521417 | ENST00000423538 | GOLGA7 | chr8 | 41364640 | + | SLC25A44 | chr1 | 156169626 | + |
3UTR-3UTR | ENST00000521417 | ENST00000469537 | GOLGA7 | chr8 | 41364640 | + | SLC25A44 | chr1 | 156169626 | + |
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FusionProtFeatures for GOLGA7_SLC25A44 |
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Hgene | Tgene |
GOLGA7 | SLC25A44 |
May be involved in protein transport from Golgi to cellsurface. The ZDHHC9-GOLGA7 complex is a palmitoyltransferasespecific for HRAS and NRAS. {ECO:0000269|PubMed:14522980,ECO:0000269|PubMed:16000296}. |
![]() * Minus value of BPloci means that the break pointn is located before the CDS. |
- In-frame and retained protein feature among the 13 regional features. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
- In-frame and not-retained protein feature among the 13 regional features. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
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FusionGeneSequence for GOLGA7_SLC25A44 |
![]() (nt: nucleotides, aa: amino acids) |
* Fusion amino acid sequences. |
* Fusion transcript sequences (only coding sequence (CDS) region). |
* Fusion transcript sequences (Full-length transcript). |
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FusionGenePPI for GOLGA7_SLC25A44 |
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Hgene | Hgene's interactors | Tgene | Tgene's interactors |
GOLGA7 | GOLGA3, PPP1CC, TSPAN3, CLDND1, TMEFF1, HAVCR2, SLC1A1, MFSD4, GYPA, NRAS | SLC25A44 | ELAVL1, JUP, NME2P1, IMPDH2, LASP1, IMPDH1 |
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Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
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Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for GOLGA7_SLC25A44 |
![]() (DrugBank Version 5.1.0 2018-04-02) |
Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for GOLGA7_SLC25A44 |
![]() (DisGeNet 4.0) |
Partner | Gene | Disease ID | Disease name | # pubmeds | Source |