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Fusion gene ID: 15037 |
FusionGeneSummary for GOLGA4_CTDSPL |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: GOLGA4_CTDSPL | Fusion gene ID: 15037 | Hgene | Tgene | Gene symbol | GOLGA4 | CTDSPL | Gene ID | 2803 | 10217 |
| Gene name | golgin A4 | CTD small phosphatase like | |
| Synonyms | CRPF46|GCP2|GOLG|MU-RMS-40.18|p230 | C3orf8|HYA22|PSR1|RBSP3|SCP3 | |
| Cytomap | 3p22.2 | 3p22.2 | |
| Type of gene | protein-coding | protein-coding | |
| Description | golgin subfamily A member 4256 kDa golgin72.1 proteincentrosome-related protein F46golgi autoantigen, golgin subfamily a, 4golgin-240golgin-245protein 72.1trans-Golgi p230 | CTD small phosphatase-like proteinCTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-likeCTDSP-likeNIF-like proteinNLI-interacting factor 1RB protein serine phosphatase from chromosome 3carboxy-terminal domain RNA poly | |
| Modification date | 20180519 | 20180523 | |
| UniProtAcc | Q13439 | O15194 | |
| Ensembl transtripts involved in fusion gene | ENST00000361924, ENST00000435830, ENST00000444882, ENST00000356847, | ENST00000443503, ENST00000273179, ENST00000310189, | |
| Fusion gene scores | * DoF score | 12 X 10 X 6=720 | 7 X 6 X 4=168 |
| # samples | 13 | 8 | |
| ** MAII score | log2(13/720*10)=-2.46948528330122 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(8/168*10)=-1.0703893278914 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: GOLGA4 [Title/Abstract] AND CTDSPL [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | GOLGA4 | GO:0043001 | Golgi to plasma membrane protein transport | 15265687 |
| Hgene | GOLGA4 | GO:0045773 | positive regulation of axon extension | 22705394 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | BRCA | TCGA-OL-A66I-01A | GOLGA4 | chr3 | 37315092 | + | CTDSPL | chr3 | 38006062 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| intron-3CDS | ENST00000361924 | ENST00000443503 | GOLGA4 | chr3 | 37315092 | + | CTDSPL | chr3 | 38006062 | + |
| intron-3CDS | ENST00000361924 | ENST00000273179 | GOLGA4 | chr3 | 37315092 | + | CTDSPL | chr3 | 38006062 | + |
| intron-3UTR | ENST00000361924 | ENST00000310189 | GOLGA4 | chr3 | 37315092 | + | CTDSPL | chr3 | 38006062 | + |
| intron-3CDS | ENST00000435830 | ENST00000443503 | GOLGA4 | chr3 | 37315092 | + | CTDSPL | chr3 | 38006062 | + |
| intron-3CDS | ENST00000435830 | ENST00000273179 | GOLGA4 | chr3 | 37315092 | + | CTDSPL | chr3 | 38006062 | + |
| intron-3UTR | ENST00000435830 | ENST00000310189 | GOLGA4 | chr3 | 37315092 | + | CTDSPL | chr3 | 38006062 | + |
| intron-3CDS | ENST00000444882 | ENST00000443503 | GOLGA4 | chr3 | 37315092 | + | CTDSPL | chr3 | 38006062 | + |
| intron-3CDS | ENST00000444882 | ENST00000273179 | GOLGA4 | chr3 | 37315092 | + | CTDSPL | chr3 | 38006062 | + |
| intron-3UTR | ENST00000444882 | ENST00000310189 | GOLGA4 | chr3 | 37315092 | + | CTDSPL | chr3 | 38006062 | + |
| In-frame | ENST00000356847 | ENST00000443503 | GOLGA4 | chr3 | 37315092 | + | CTDSPL | chr3 | 38006062 | + |
| In-frame | ENST00000356847 | ENST00000273179 | GOLGA4 | chr3 | 37315092 | + | CTDSPL | chr3 | 38006062 | + |
| 5CDS-3UTR | ENST00000356847 | ENST00000310189 | GOLGA4 | chr3 | 37315092 | + | CTDSPL | chr3 | 38006062 | + |
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FusionProtFeatures for GOLGA4_CTDSPL |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| GOLGA4 | CTDSPL |
| Involved in vesicular trafficking at the Golgi apparatuslevel. May play a role in delivery of transport vesiclescontaining GPI-linked proteins from the trans-Golgi networkthrough its interaction with MACF1. Involved in endosome-to-Golgitrafficking (PubMed:29084197). {ECO:0000269|PubMed:15265687,ECO:0000269|PubMed:29084197}. | Recruited by REST to neuronal genes that contain RE-1elements, leading to neuronal gene silencing in non-neuronal cells(By similarity). Preferentially catalyzes the dephosphorylation of'Ser-5' within the tandem 7 residue repeats in the C-terminaldomain (CTD) of the largest RNA polymerase II subunit POLR2A.Negatively regulates RNA polymerase II transcription, possibly bycontrolling the transition from initiation/capping to processivetranscript elongation. {ECO:0000250, ECO:0000269|PubMed:12721286}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
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FusionGeneSequence for GOLGA4_CTDSPL |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_GOLGA4_ENST00000356847_chr3_37315092_+_CTDSPL_ENST00000443503_chr3_38006062_+_264aa MFKKLKQKISEEQQQLQQALAPAQASSNSSTPTRMRSRTSSFTEQLDEGTPNRENASTHASKSPDSVNGSEPSIPQPPAKYLLPEVTVLD YGKKCVVIDLDETLVHSSFKPISNADFIVPVEIDGTIHQVYVLKRPHVDEFLQRMGQLFECVLFTASLAKYADPVADLLDRWGVFRARLF >In-frame_GOLGA4_ENST00000356847_chr3_37315092_+_CTDSPL_ENST00000273179_chr3_38006062_+_264aa MFKKLKQKISEEQQQLQQALAPAQASSNSSTPTRMRSRTSSFTEQLDEGTPNRENASTHASKSPDSVNGSEPSIPQPPAKYLLPEVTVLD YGKKCVVIDLDETLVHSSFKPISNADFIVPVEIDGTIHQVYVLKRPHVDEFLQRMGQLFECVLFTASLAKYADPVADLLDRWGVFRARLF |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_GOLGA4_ENST00000356847_chr3_37315092_+_CTDSPL_ENST00000443503_chr3_38006062_+_792nt ATGTTCAAGAAACTGAAGCAAAAGATCAGCGAGGAGCAGCAGCAGCTCCAGCAGGCGCTGGCTCCTGCTCAGGCGTCCTCCAATTCTTCA ACACCAACAAGAATGAGGAGCAGGACATCTTCATTTACAGAGCAACTTGATGAAGGTACACCCAATAGAGAGAATGCATCTACTCATGCC TCGAAATCTCCTGACAGTGTTAATGGAAGTGAACCAAGCATTCCTCAGCCACCAGCTAAGTACCTTCTTCCAGAGGTGACGGTGCTTGAC TATGGAAAGAAATGTGTGGTCATTGATTTAGATGAAACATTGGTGCACAGTTCGTTTAAGCCTATTAGTAATGCTGATTTTATTGTTCCG GTTGAAATCGATGGAACTATACATCAGGTGTATGTGCTGAAGCGGCCACATGTGGACGAGTTCCTCCAGAGGATGGGGCAGCTTTTTGAA TGTGTGCTCTTTACTGCCAGCTTGGCCAAGTATGCAGACCCTGTGGCTGACCTCCTAGACCGCTGGGGTGTGTTCCGGGCCCGGCTCTTC AGAGAATCATGTGTTTTTCATCGTGGGAACTACGTGAAGGACCTGAGTCGCCTTGGGCGGGAGCTGAGCAAAGTGATCATTGTTGACAAT TCCCCTGCCTCATACATCTTCCATCCTGAGAATGCAGTGCCTGTGCAGTCCTGGTTCGATGACATGACGGACACGGAGCTGCTGGACCTC >In-frame_GOLGA4_ENST00000356847_chr3_37315092_+_CTDSPL_ENST00000273179_chr3_38006062_+_792nt ATGTTCAAGAAACTGAAGCAAAAGATCAGCGAGGAGCAGCAGCAGCTCCAGCAGGCGCTGGCTCCTGCTCAGGCGTCCTCCAATTCTTCA ACACCAACAAGAATGAGGAGCAGGACATCTTCATTTACAGAGCAACTTGATGAAGGTACACCCAATAGAGAGAATGCATCTACTCATGCC TCGAAATCTCCTGACAGTGTTAATGGAAGTGAACCAAGCATTCCTCAGCCACCAGCTAAGTACCTTCTTCCAGAGGTGACGGTGCTTGAC TATGGAAAGAAATGTGTGGTCATTGATTTAGATGAAACATTGGTGCACAGTTCGTTTAAGCCTATTAGTAATGCTGATTTTATTGTTCCG GTTGAAATCGATGGAACTATACATCAGGTGTATGTGCTGAAGCGGCCACATGTGGACGAGTTCCTCCAGAGGATGGGGCAGCTTTTTGAA TGTGTGCTCTTTACTGCCAGCTTGGCCAAGTATGCAGACCCTGTGGCTGACCTCCTAGACCGCTGGGGTGTGTTCCGGGCCCGGCTCTTC AGAGAATCATGTGTTTTTCATCGTGGGAACTACGTGAAGGACCTGAGTCGCCTTGGGCGGGAGCTGAGCAAAGTGATCATTGTTGACAAT TCCCCTGCCTCATACATCTTCCATCCTGAGAATGCAGTGCCTGTGCAGTCCTGGTTCGATGACATGACGGACACGGAGCTGCTGGACCTC |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_GOLGA4_ENST00000356847_chr3_37315092_+_CTDSPL_ENST00000443503_chr3_38006062_+_4693nt GCAAGCGCCCTTGGCGCACAGTTCACCTGCTGCCGTTGTCGTCGCCGCCGCGGCTCCCGGGGCTGGATGGGGGGCCGAGGCCAGCCAGTG GCACCCGGAAGAAAGAGACGCGGCGGCGGCGACGCCGACACCCTCAGGACGAGTGTCCGGACTTGCCCACAGCCTCAAGGAGGAGACGGC GAGGCCCGGCCCCCGCTGTCCCTGGTGTAAAGAAGTCGCCGTAGCCGTCGCGGCCGGGACTCCCCGGGCTCTCGCCCTTCAGGTTTCGTT GACACTCAGGACCGTACGTACGCTGCGCCATGTTCAAGAAACTGAAGCAAAAGATCAGCGAGGAGCAGCAGCAGCTCCAGCAGGCGCTGG CTCCTGCTCAGGCGTCCTCCAATTCTTCAACACCAACAAGAATGAGGAGCAGGACATCTTCATTTACAGAGCAACTTGATGAAGGTACAC CCAATAGAGAGAATGCATCTACTCATGCCTCGAAATCTCCTGACAGTGTTAATGGAAGTGAACCAAGCATTCCTCAGCCACCAGCTAAGT ACCTTCTTCCAGAGGTGACGGTGCTTGACTATGGAAAGAAATGTGTGGTCATTGATTTAGATGAAACATTGGTGCACAGTTCGTTTAAGC CTATTAGTAATGCTGATTTTATTGTTCCGGTTGAAATCGATGGAACTATACATCAGGTGTATGTGCTGAAGCGGCCACATGTGGACGAGT TCCTCCAGAGGATGGGGCAGCTTTTTGAATGTGTGCTCTTTACTGCCAGCTTGGCCAAGTATGCAGACCCTGTGGCTGACCTCCTAGACC GCTGGGGTGTGTTCCGGGCCCGGCTCTTCAGAGAATCATGTGTTTTTCATCGTGGGAACTACGTGAAGGACCTGAGTCGCCTTGGGCGGG AGCTGAGCAAAGTGATCATTGTTGACAATTCCCCTGCCTCATACATCTTCCATCCTGAGAATGCAGTGCCTGTGCAGTCCTGGTTCGATG ACATGACGGACACGGAGCTGCTGGACCTCATCCCCTTCTTTGAGGGCCTGAGCCGGGAGGACGACGTGTACAGCATGCTGCACAGACTCT GCAATAGGTAGCCCTGGCCTCTGCCTGCCTCCCGCCTGTGCACTCTGGAACCTCTGGCCTCAGGGGACCTGCCTGTCCTCAGCTCCCTGG GAGCTGAAAGTGAGGATACTCCGTGCTCCAGGCCACAGGGTGAATGTGGCCATGCCTACCTGTTTTGTTTTTTTAAGAACAGAAACAACT ATTTTAAAAGAACTCTTTTAAGAAATTTCATAAAGGGACATGCATTTTACTGGGTTTGCTTTTCTTAAAACATACCAAAAAAGAAAAAAA TAGAAAAAAAAAAAAAAAAAGCTTGATCTCTATCAGACTTCCTTTCAACTGTCCTCCCCTCCAAGCAGACCACCTGTCCCCTTCTATCCC AGCTCAGAGCAGCTGACCCAACTCAGAATCTCTTTCCTACAGGATGAAGTGCCTTTTGAATGTTATTTTAAGCCGAGAGTTAATTTTTCT ACACAACATATTTCCAGACATCTTTTAGTCTTTTATTGTCTTAGATACTATAAGAAGATGAACATGACAATTTTCTAGAACCTGGTAGCG TGTGTGTGTGTGGCGGGGGGTGCTGAGGGAGGGGAGTGAGTCACAGGAGCCTGTCCCCCAACAGGTGTGACTGCTCTGACAACCTGTGGC ATGCTGCAGGGTCAGGCTCCTGATAGGAGGATTTCATGACTATGTCATTGTCTCCACTCATTTTTGACCCAGTTTGGAATGTATCTGCAA TTGTGTGGCTCAACACTTTAGGAAACAATAGATTATTTTATATTATTATTTCTGATGGTGACAAGTTTGTCTTGAGGTCACATTTTCTCC TTGAAAAGTGACATCCTGTCACTTCTGCTCTCACACTACTGCCATACATTTGTGTTTTTTGTTGTTATTGTTTGGGTAGAGCAGTTACAA GAAACCCTAAAACCCTTGGATATAAAAGAAATCTGTTTATTGATTTTTAAATCTTTCCTTTCCAAAAGCTGGATACACATGGAGCTGTTT GGGAATTTTCCTTGCTGCTACCGCGCTGCCACCAAATGGAATTGACCAGCGGCTGTTACACTGTTCTTTGCCACTGTGCCTATGCTCAGA ATATGCTCACTGCTAAGCTACAAACTCGGACAGGGTCAGAAACAGAGGTGTCCCATCCCATTGCAGCCTCCACCACCTGTAACCCCTTCC TGGCATTGGCCACTGAAGGGTACAAAGGCAAAAGGACCACAGCACCACTTAGGTGTAGCATGGATTTTAAACTGCAGTCAGTATCAGATC CTGTTTGATAAATAAGCTGACTGTTCTCTCTTGAGAACCTGTGGCCTCAACCAGCCACCAAGCTGATGTGGCCCAAGTCCATCTCTTGGT CTTCTCCTTTGAAGCACAGCCTATTTCTGAGCCAAGGGTTGGGGAAGCCTGTCTAGATGTGGGACTCATTGCCCCAAACCAGGGAGAGGA AGAGCTCCCACAGGGAGAGCCCAGGCTCTCTTTGCAGCCTTTCCCAGTTTGGTGTTTAAGCAGTGCCATGTTCCTTGTTTGACAACAAGA CAGTCTGTAAAGTATTGCTCTTAAAAACAATTAAAAAGAACCCTTTCATATTGGCACCATTGCCTTAGTCCTCTGTGGGTTGGTCTTCAG CCAGCATTCTGGTGGGAGTGACTGGCATTAACAAGACTGGAAATCGGGGGTCAAAGTAAAATATCTTTGTTTTGCTTTCATTCACAAAGT AATGAAGCCAGCTGCCAATTACATCCTCCCAACAGCACTTTGGTCTGTGGACTGCTGTGTGAATATTCAGAAGGGAAGTAAGTATTCAGG GGGTAAACAGGTCTCCCAGCATTCTGAGTGTTCCAAACCAGTAATCCACATGCCAATTCAAATAGAACAGCCCCTTGCTAGATATTACCA CAGATAATGACAGTTACATGGTAGAACTGCCCATGCCACAAATATTTATTTGGAAAAGTAGTCATTAAATGAACCCACTGCCTTAAATGT CTTGAATGTTGCAGTCAAGTGTCTGTCATGTGTTGATATCCACACAGAATTAGGCCCTAATGAGAGCCTTAGACCCTCAACCATGCCCCC TTCGTTGGCATCACAGGGCCTTATTTGGAAGAGCGGGCAAAGAGGATGGAAATCATAAAATATTTCATGGGAATCGAACCTAGGGATAGT GCTCCACTTCTGACGATGGAGTGAAGACACTTGGCAGACTTGAGCCAGACACTTCACCTAGTAGTTCCTGAAACTGTGAGCACCACTGCA CTAAGCCAGTGCGGAGCTGTTAGGGACGGGCCCAGCTCCTGCACCACGGACACAGAATGTCTGGAGAGGGCCAGCAGGCCCTCTGAGGGT TCTGGAATCTGTGCACCTTATTTGACCACACTCCAAAATTCTGTTTTTATTTTAACCCTTGAATCTGCTTTATGTACATAATCAAAATAT CTATATCTATATCTATATCTATATCTATATATTTTTAATCATCTACATGTAAATGAAGCAATAGAATTCTAACATAAGGCCAAGAAATGA GACGAATGTTTGGGGTTTATGTTTTTTAAGGTAAATACGGGTATTGTTTTTAATTATTACCATGTATTAAATTGTGGGCTTTGAAACCTA ATGAAACCTGTTAGCCACTTCTCTGTGCCATATACTTCCCATGTTACCAAAATACCCCCAACTCTTTAGCCAAAAGAGAACCCTGACCTC CTGAGTTTCCATGCTCCTTTCTGTACCAGGTTTAAATGTAGTCTTCTGGAGAAGTATTTTTGACATTGAGCTCTGGGACAGGACACCTTG GGTTTGTGGACTGCAGCCCACTATGATGTTATTACTTCTCTGGCCAGGCCTCCAGTGGAAGTGCACAGGCACTCCCAATGTTGTTAATGC TCTGTCTTCCATTTGTTCTGGAATCCTACGTGTTGGTCTGTGGTTCCATGCATTAGCTGTTTGTAAATAATGCATTTGCATACTGAAAAA GGAATGCCACCTGCCACAGTTGATGGTGAGGAAGCTCCTTTGACGTGGTGCAATTTTGATGAGATGTCTCTGGGGACACGAGGATGCCCT AATGATGCTGACTTGTCATGGTTGCAGCATTTGAACTTTTGGTGTTAAAAAAAAAAACCTGTAAGTCTGTAACCTGGCAACATTTTACAA CCCTGTATTTTTAAAGATGGCTTTCTAATAAAAAATCCAGAACCACACAGCCCTATGGTCAAACAATCCTACGTTTGTGCCTCTGCTTTT AAAGGTGCTGTGCTGGACAGTTGGCATGCCAGGGTTCGAGAAGAGTGAATGGCTTGACGTACTTGCAGTTAACTGTGCAAAATTGGCTGG CTGCCTCTGTTCCTACTGTACTGTAACTTTGATCATGTCTGTTCCTGTTCCATTCTCCCAGGAGCTTCTCTGCAGACTGACACACCCTCC CCCACCCCGGGTAGTGGAGATGCTGGTGTCTGGGTAGTCATGGATTTCTGCTGGACATTTGAATGTGATAAACAATCCAGCATTACTTAG GAAATGCTACATGCGGAATGTGCACGTTTCCAGGGGCGAGTATTGTCAATCAAAAGGTTTGCAATGATTTCCTTCCTGCCAAAAATAAAC >In-frame_GOLGA4_ENST00000356847_chr3_37315092_+_CTDSPL_ENST00000273179_chr3_38006062_+_4693nt GCAAGCGCCCTTGGCGCACAGTTCACCTGCTGCCGTTGTCGTCGCCGCCGCGGCTCCCGGGGCTGGATGGGGGGCCGAGGCCAGCCAGTG GCACCCGGAAGAAAGAGACGCGGCGGCGGCGACGCCGACACCCTCAGGACGAGTGTCCGGACTTGCCCACAGCCTCAAGGAGGAGACGGC GAGGCCCGGCCCCCGCTGTCCCTGGTGTAAAGAAGTCGCCGTAGCCGTCGCGGCCGGGACTCCCCGGGCTCTCGCCCTTCAGGTTTCGTT GACACTCAGGACCGTACGTACGCTGCGCCATGTTCAAGAAACTGAAGCAAAAGATCAGCGAGGAGCAGCAGCAGCTCCAGCAGGCGCTGG CTCCTGCTCAGGCGTCCTCCAATTCTTCAACACCAACAAGAATGAGGAGCAGGACATCTTCATTTACAGAGCAACTTGATGAAGGTACAC CCAATAGAGAGAATGCATCTACTCATGCCTCGAAATCTCCTGACAGTGTTAATGGAAGTGAACCAAGCATTCCTCAGCCACCAGCTAAGT ACCTTCTTCCAGAGGTGACGGTGCTTGACTATGGAAAGAAATGTGTGGTCATTGATTTAGATGAAACATTGGTGCACAGTTCGTTTAAGC CTATTAGTAATGCTGATTTTATTGTTCCGGTTGAAATCGATGGAACTATACATCAGGTGTATGTGCTGAAGCGGCCACATGTGGACGAGT TCCTCCAGAGGATGGGGCAGCTTTTTGAATGTGTGCTCTTTACTGCCAGCTTGGCCAAGTATGCAGACCCTGTGGCTGACCTCCTAGACC GCTGGGGTGTGTTCCGGGCCCGGCTCTTCAGAGAATCATGTGTTTTTCATCGTGGGAACTACGTGAAGGACCTGAGTCGCCTTGGGCGGG AGCTGAGCAAAGTGATCATTGTTGACAATTCCCCTGCCTCATACATCTTCCATCCTGAGAATGCAGTGCCTGTGCAGTCCTGGTTCGATG ACATGACGGACACGGAGCTGCTGGACCTCATCCCCTTCTTTGAGGGCCTGAGCCGGGAGGACGACGTGTACAGCATGCTGCACAGACTCT GCAATAGGTAGCCCTGGCCTCTGCCTGCCTCCCGCCTGTGCACTCTGGAACCTCTGGCCTCAGGGGACCTGCCTGTCCTCAGCTCCCTGG GAGCTGAAAGTGAGGATACTCCGTGCTCCAGGCCACAGGGTGAATGTGGCCATGCCTACCTGTTTTGTTTTTTTAAGAACAGAAACAACT ATTTTAAAAGAACTCTTTTAAGAAATTTCATAAAGGGACATGCATTTTACTGGGTTTGCTTTTCTTAAAACATACCAAAAAAGAAAAAAA TAGAAAAAAAAAAAAAAAAAGCTTGATCTCTATCAGACTTCCTTTCAACTGTCCTCCCCTCCAAGCAGACCACCTGTCCCCTTCTATCCC AGCTCAGAGCAGCTGACCCAACTCAGAATCTCTTTCCTACAGGATGAAGTGCCTTTTGAATGTTATTTTAAGCCGAGAGTTAATTTTTCT ACACAACATATTTCCAGACATCTTTTAGTCTTTTATTGTCTTAGATACTATAAGAAGATGAACATGACAATTTTCTAGAACCTGGTAGCG TGTGTGTGTGTGGCGGGGGGTGCTGAGGGAGGGGAGTGAGTCACAGGAGCCTGTCCCCCAACAGGTGTGACTGCTCTGACAACCTGTGGC ATGCTGCAGGGTCAGGCTCCTGATAGGAGGATTTCATGACTATGTCATTGTCTCCACTCATTTTTGACCCAGTTTGGAATGTATCTGCAA TTGTGTGGCTCAACACTTTAGGAAACAATAGATTATTTTATATTATTATTTCTGATGGTGACAAGTTTGTCTTGAGGTCACATTTTCTCC TTGAAAAGTGACATCCTGTCACTTCTGCTCTCACACTACTGCCATACATTTGTGTTTTTTGTTGTTATTGTTTGGGTAGAGCAGTTACAA GAAACCCTAAAACCCTTGGATATAAAAGAAATCTGTTTATTGATTTTTAAATCTTTCCTTTCCAAAAGCTGGATACACATGGAGCTGTTT GGGAATTTTCCTTGCTGCTACCGCGCTGCCACCAAATGGAATTGACCAGCGGCTGTTACACTGTTCTTTGCCACTGTGCCTATGCTCAGA ATATGCTCACTGCTAAGCTACAAACTCGGACAGGGTCAGAAACAGAGGTGTCCCATCCCATTGCAGCCTCCACCACCTGTAACCCCTTCC TGGCATTGGCCACTGAAGGGTACAAAGGCAAAAGGACCACAGCACCACTTAGGTGTAGCATGGATTTTAAACTGCAGTCAGTATCAGATC CTGTTTGATAAATAAGCTGACTGTTCTCTCTTGAGAACCTGTGGCCTCAACCAGCCACCAAGCTGATGTGGCCCAAGTCCATCTCTTGGT CTTCTCCTTTGAAGCACAGCCTATTTCTGAGCCAAGGGTTGGGGAAGCCTGTCTAGATGTGGGACTCATTGCCCCAAACCAGGGAGAGGA AGAGCTCCCACAGGGAGAGCCCAGGCTCTCTTTGCAGCCTTTCCCAGTTTGGTGTTTAAGCAGTGCCATGTTCCTTGTTTGACAACAAGA CAGTCTGTAAAGTATTGCTCTTAAAAACAATTAAAAAGAACCCTTTCATATTGGCACCATTGCCTTAGTCCTCTGTGGGTTGGTCTTCAG CCAGCATTCTGGTGGGAGTGACTGGCATTAACAAGACTGGAAATCGGGGGTCAAAGTAAAATATCTTTGTTTTGCTTTCATTCACAAAGT AATGAAGCCAGCTGCCAATTACATCCTCCCAACAGCACTTTGGTCTGTGGACTGCTGTGTGAATATTCAGAAGGGAAGTAAGTATTCAGG GGGTAAACAGGTCTCCCAGCATTCTGAGTGTTCCAAACCAGTAATCCACATGCCAATTCAAATAGAACAGCCCCTTGCTAGATATTACCA CAGATAATGACAGTTACATGGTAGAACTGCCCATGCCACAAATATTTATTTGGAAAAGTAGTCATTAAATGAACCCACTGCCTTAAATGT CTTGAATGTTGCAGTCAAGTGTCTGTCATGTGTTGATATCCACACAGAATTAGGCCCTAATGAGAGCCTTAGACCCTCAACCATGCCCCC TTCGTTGGCATCACAGGGCCTTATTTGGAAGAGCGGGCAAAGAGGATGGAAATCATAAAATATTTCATGGGAATCGAACCTAGGGATAGT GCTCCACTTCTGACGATGGAGTGAAGACACTTGGCAGACTTGAGCCAGACACTTCACCTAGTAGTTCCTGAAACTGTGAGCACCACTGCA CTAAGCCAGTGCGGAGCTGTTAGGGACGGGCCCAGCTCCTGCACCACGGACACAGAATGTCTGGAGAGGGCCAGCAGGCCCTCTGAGGGT TCTGGAATCTGTGCACCTTATTTGACCACACTCCAAAATTCTGTTTTTATTTTAACCCTTGAATCTGCTTTATGTACATAATCAAAATAT CTATATCTATATCTATATCTATATCTATATATTTTTAATCATCTACATGTAAATGAAGCAATAGAATTCTAACATAAGGCCAAGAAATGA GACGAATGTTTGGGGTTTATGTTTTTTAAGGTAAATACGGGTATTGTTTTTAATTATTACCATGTATTAAATTGTGGGCTTTGAAACCTA ATGAAACCTGTTAGCCACTTCTCTGTGCCATATACTTCCCATGTTACCAAAATACCCCCAACTCTTTAGCCAAAAGAGAACCCTGACCTC CTGAGTTTCCATGCTCCTTTCTGTACCAGGTTTAAATGTAGTCTTCTGGAGAAGTATTTTTGACATTGAGCTCTGGGACAGGACACCTTG GGTTTGTGGACTGCAGCCCACTATGATGTTATTACTTCTCTGGCCAGGCCTCCAGTGGAAGTGCACAGGCACTCCCAATGTTGTTAATGC TCTGTCTTCCATTTGTTCTGGAATCCTACGTGTTGGTCTGTGGTTCCATGCATTAGCTGTTTGTAAATAATGCATTTGCATACTGAAAAA GGAATGCCACCTGCCACAGTTGATGGTGAGGAAGCTCCTTTGACGTGGTGCAATTTTGATGAGATGTCTCTGGGGACACGAGGATGCCCT AATGATGCTGACTTGTCATGGTTGCAGCATTTGAACTTTTGGTGTTAAAAAAAAAAACCTGTAAGTCTGTAACCTGGCAACATTTTACAA CCCTGTATTTTTAAAGATGGCTTTCTAATAAAAAATCCAGAACCACACAGCCCTATGGTCAAACAATCCTACGTTTGTGCCTCTGCTTTT AAAGGTGCTGTGCTGGACAGTTGGCATGCCAGGGTTCGAGAAGAGTGAATGGCTTGACGTACTTGCAGTTAACTGTGCAAAATTGGCTGG CTGCCTCTGTTCCTACTGTACTGTAACTTTGATCATGTCTGTTCCTGTTCCATTCTCCCAGGAGCTTCTCTGCAGACTGACACACCCTCC CCCACCCCGGGTAGTGGAGATGCTGGTGTCTGGGTAGTCATGGATTTCTGCTGGACATTTGAATGTGATAAACAATCCAGCATTACTTAG GAAATGCTACATGCGGAATGTGCACGTTTCCAGGGGCGAGTATTGTCAATCAAAAGGTTTGCAATGATTTCCTTCCTGCCAAAAATAAAC |
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FusionGenePPI for GOLGA4_CTDSPL |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| GOLGA4 | ARL1, ARL3, TRAF3IP1, EXOC1, TNIK, APP, TP63, NOL11, ZER1, SMYD2, LIMD1, CIRH1A, UBR7, HNRNPD, VHL, GEMIN5, TMEM63B, VWA9, PPM1H, PTPRN2, CCDC53, RALBP1, BMP1, NECAB2, TKT, ATP5G3, SERPINB5 | CTDSPL | SNAI1, ELAVL1, CTDSP1, CDCA3, TBC1D4, ARVCF, CADM1, RFTN1, PACS1, DAB2IP, ARHGAP39, CD44, ABCC1, ATP2B4, NOTCH1, PVRL2, MCAM, ITGA5, USP31, C2CD4C, TBC1D10B, TIAM1, ITGA6, KIRREL, SPTBN2, PPP1R9A, CDC42EP1, TMEM2, CACHD1, MICAL3, ANK3, FMN2, ROBO1, MPZL1, ADD2, PALM2, NUMBL, AKAP5, SLC30A1, KIAA1549, CTNNA1, FLVCR1, SLC29A1, CXADR, FAM171B, TTC7B, PCDH7, MARVELD2, NF2, SLC39A6, BASP1, CNNM3, SLC39A10, CLCN7, GPRIN3, ESYT2, FAM171A1, LPHN2, RELL1, SLC12A7, NUMB, CEP89, SLC12A2, CTNND1, DTNA, CCDC8, SLC38A1, TJP1, ZDHHC5, PALM, EGFR, PTPN14, TULP3, FAM129B, GPRIN1, HSPA12A, ATP2B1, EFR3B, SLC3A2, ARL13B, PSD3, MBP, FGFR2 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for GOLGA4_CTDSPL |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for GOLGA4_CTDSPL |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | GOLGA4 | C0033578 | Prostatic Neoplasms | 1 | CTD_human |
| Hgene | GOLGA4 | C0037274 | Dermatologic disorders | 1 | CTD_human |
| Hgene | GOLGA4 | C0311375 | Arsenic Poisoning | 1 | CTD_human |
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