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Fusion gene ID: 14943 |
FusionGeneSummary for GNE_ROCK1 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: GNE_ROCK1 | Fusion gene ID: 14943 | Hgene | Tgene | Gene symbol | GNE | ROCK1 | Gene ID | 10020 | 6093 |
| Gene name | glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase | Rho associated coiled-coil containing protein kinase 1 | |
| Synonyms | DMRV|GLCNE|IBM2|NM|Uae1 | P160ROCK|ROCK-I | |
| Cytomap | 9p13.3 | 18q11.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinaseN-acylmannosamine kinaseUDP-GlcNAc-2-epimerase/ManAc kinaseUDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase | rho-associated protein kinase 1p160 ROCK-1renal carcinoma antigen NY-REN-35 | |
| Modification date | 20180519 | 20180527 | |
| UniProtAcc | Q9Y223 | Q13464 | |
| Ensembl transtripts involved in fusion gene | ENST00000396594, ENST00000539815, ENST00000543356, ENST00000539208, ENST00000447283, ENST00000377902, | ENST00000399799, | |
| Fusion gene scores | * DoF score | 6 X 6 X 4=144 | 2 X 2 X 2=8 |
| # samples | 6 | 2 | |
| ** MAII score | log2(6/144*10)=-1.26303440583379 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(2/8*10)=1.32192809488736 | |
| Context | PubMed: GNE [Title/Abstract] AND ROCK1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Tgene | ROCK1 | GO:0007159 | leukocyte cell-cell adhesion | 12082081 |
| Tgene | ROCK1 | GO:0022614 | membrane to membrane docking | 12082081 |
| Tgene | ROCK1 | GO:0032091 | negative regulation of protein binding | 18573880 |
| Tgene | ROCK1 | GO:0032956 | regulation of actin cytoskeleton organization | 25911094 |
| Tgene | ROCK1 | GO:0050900 | leukocyte migration | 12082081 |
| Tgene | ROCK1 | GO:0050901 | leukocyte tethering or rolling | 12082081 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | LUSC | TCGA-56-A49D-01A | GNE | chr9 | 36236829 | - | ROCK1 | chr18 | 18650574 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| Frame-shit | ENST00000396594 | ENST00000399799 | GNE | chr9 | 36236829 | - | ROCK1 | chr18 | 18650574 | - |
| Frame-shit | ENST00000539815 | ENST00000399799 | GNE | chr9 | 36236829 | - | ROCK1 | chr18 | 18650574 | - |
| Frame-shit | ENST00000543356 | ENST00000399799 | GNE | chr9 | 36236829 | - | ROCK1 | chr18 | 18650574 | - |
| intron-3CDS | ENST00000539208 | ENST00000399799 | GNE | chr9 | 36236829 | - | ROCK1 | chr18 | 18650574 | - |
| In-frame | ENST00000447283 | ENST00000399799 | GNE | chr9 | 36236829 | - | ROCK1 | chr18 | 18650574 | - |
| In-frame | ENST00000377902 | ENST00000399799 | GNE | chr9 | 36236829 | - | ROCK1 | chr18 | 18650574 | - |
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FusionProtFeatures for GNE_ROCK1 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| GNE | ROCK1 |
| Protein kinase which is a key regulator of actincytoskeleton and cell polarity. Involved in regulation of smoothmuscle contraction, actin cytoskeleton organization, stress fiberand focal adhesion formation, neurite retraction, cell adhesionand motility via phosphorylation of DAPK3, GFAP, LIMK1, LIMK2,MYL9/MLC2, PFN1 and PPP1R12A. Phosphorylates FHOD1 and actssynergistically with it to promote SRC-dependent non-apoptoticplasma membrane blebbing. Phosphorylates JIP3 and regulates therecruitment of JNK to JIP3 upon UVB-induced stress. Acts as asuppressor of inflammatory cell migration by regulating PTENphosphorylation and stability. Acts as a negative regulator ofVEGF-induced angiogenic endothelial cell activation. Required forcentrosome positioning and centrosome-dependent exit from mitosis.Plays a role in terminal erythroid differentiation. May regulateclosure of the eyelids and ventral body wall by inducing theassembly of actomyosin bundles. Promotes keratinocyte terminaldifferentiation. Involved in osteoblast compaction through thefibronectin fibrillogenesis cell-mediated matrix assembly process,essential for osteoblast mineralization.{ECO:0000269|PubMed:10436159, ECO:0000269|PubMed:10652353,ECO:0000269|PubMed:11018042, ECO:0000269|PubMed:11283607,ECO:0000269|PubMed:17158456, ECO:0000269|PubMed:18573880,ECO:0000269|PubMed:18694941, ECO:0000269|PubMed:19036714,ECO:0000269|PubMed:19131646, ECO:0000269|PubMed:19181962,ECO:0000269|PubMed:19997641, ECO:0000269|PubMed:21072057,ECO:0000269|PubMed:8617235, ECO:0000269|PubMed:9722579}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
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FusionGeneSequence for GNE_ROCK1 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_GNE_ENST00000447283_chr9_36236829_-_ROCK1_ENST00000399799_chr18_18650574_-_1580aa MEKNGNNRKLRVCVATCNRADTSKLAPIMFGIKTEPEFFELDVVVLGSHLIDDTGNTTRMIEQDDFDINTRLHTIVRGEDEAAMVESVGL ALVKLPDVLNRLKPDIMIVHGDRFDALALATSAALMNIRILHIEGGEVSGTIDDSIRHAITKLAHTHVCCTRSAEQHLISMCEDHDRILL AGCPSTDKLLSAKNKDYMSIIRMWLGDDVKSKDYIVALQHPVTTDIKHSIKMFELTLDALISFNKRTLVLFPNIDAGWIGCFGI_FGFSC LKKKQKT_QLFKQI_RHNK_NQRFTNES_RL_SSEGDW_RCIWRSSIGKA_IHQEGICTEASQQI_NDKEI_FCFFLGRKGHHGFCQQSL GCSAFLCIPR_SLSLHGDGIHAWWRSCKLNEQL_CA_KMGTILYCRSSSCIGCNPFHGFTSQRCEA__HAAG_IWTFEVSRFWYLTEDE_ GRHGTM_YSGWNT_LTFP_SIKIPRW_WLLWKRM_LVVGWGIFIRNACR_YTFLCRFFGWNLQ_NTEP_KFTYLS____HIKRSKKPTLC LPY_QGSEVRAKWCRRNQTTSLLQK_PVGLGNAPRHCSTSCTRFK__H_Y__F__LGRR_RRGRNIPTS_SFRWQSTTFCRIYIL_QS_I LIFSKS___QN_LQCR_KLAGKFAKNNL_AGRTAA__NAVKR_NGAEVQNLKHKTRQDNERIG_RGKSKKKSRIYSVSD_EGENVATA_N __VPKKS_TGK_EEKKCRK_SFYIKGSVGRLKESQSEFTAC__EAVPVTKAARRSQ_LT_DRIGHSCKIEEESHRDEQVN_SVRVPEQRV AREKSNFREF_VTNRQRLLPAASTIRS_TKRQRS_F_DDWRPSSSNYIFTRGGEASQT_SRKSGRRKKRGSRHA_SLRKGKE_FRDRFKL QT_IITTTVRTRGK_TQSNQSSFN_QTSIT_RGKVCGNV_DGKKAERRKRSSREG_KSGCSD_ETVFHARR_SEAISAETRTFDWK_RKD GG_S_ESNPATGAGIK_AAVVTK_IEDSSI_GRQFKRFRKADETGNKYFIGSKEIIRI_VSSAYETV_RK_RTDAGATRSA_S_AIFLDT L_NPGKGT_RRN_RKKQRKFKENTGTTK_KRNSCYSVGSSRNKS_V_AVGARPSGRTVF_IDARKQESCFKK_TRDYR_RSHC_SA_RSK QHANQRT_NIKKRE_RANRENEEGRGRI_TGEGGGDQ_S_GCL_KETQH_TNP_NTGC_QIGRNNESKRF_N__KES_YTRFEKERKGKS KAATGTQPRKREIQPDGSETSEGTE_HASAIGRRMCT_E_ASDAVGQQRE_T_AIAC_TFGPLGFYKCC_FS_C__N_W_PPRVKN_RLA FSTK_RKTQTIWLEETVCCGKQQKNFVL__RTR_GAIQSITGIGHR_TVSR_TCNPRRCV_S_N_RNS_NIPDTICK_R_M_KRCRDGTS TTS_KN_FPKSQRP_VTSYTLPLSCQL_CLCQTSLACF_ATPCPRVSKMPC_VPQRSLR_ERGLNLSM_SKL_CNISKRTAAVSMFSG_T >In-frame_GNE_ENST00000377902_chr9_36236829_-_ROCK1_ENST00000399799_chr18_18650574_-_1580aa MEKNGNNRKLRVCVATCNRADTSKLAPIMFGIKTEPEFFELDVVVLGSHLIDDTGNTTRMIEQDDFDINTRLHTIVRGEDEAAMVESVGL ALVKLPDVLNRLKPDIMIVHGDRFDALALATSAALMNIRILHIEGGEVSGTIDDSIRHAITKLAHTHVCCTRSAEQHLISMCEDHDRILL AGCPSTDKLLSAKNKDYMSIIRMWLGDDVKSKDYIVALQHPVTTDIKHSIKMFELTLDALISFNKRTLVLFPNIDAGWIGCFGI_FGFSC LKKKQKT_QLFKQI_RHNK_NQRFTNES_RL_SSEGDW_RCIWRSSIGKA_IHQEGICTEASQQI_NDKEI_FCFFLGRKGHHGFCQQSL GCSAFLCIPR_SLSLHGDGIHAWWRSCKLNEQL_CA_KMGTILYCRSSSCIGCNPFHGFTSQRCEA__HAAG_IWTFEVSRFWYLTEDE_ GRHGTM_YSGWNT_LTFP_SIKIPRW_WLLWKRM_LVVGWGIFIRNACR_YTFLCRFFGWNLQ_NTEP_KFTYLS____HIKRSKKPTLC LPY_QGSEVRAKWCRRNQTTSLLQK_PVGLGNAPRHCSTSCTRFK__H_Y__F__LGRR_RRGRNIPTS_SFRWQSTTFCRIYIL_QS_I LIFSKS___QN_LQCR_KLAGKFAKNNL_AGRTAA__NAVKR_NGAEVQNLKHKTRQDNERIG_RGKSKKKSRIYSVSD_EGENVATA_N __VPKKS_TGK_EEKKCRK_SFYIKGSVGRLKESQSEFTAC__EAVPVTKAARRSQ_LT_DRIGHSCKIEEESHRDEQVN_SVRVPEQRV AREKSNFREF_VTNRQRLLPAASTIRS_TKRQRS_F_DDWRPSSSNYIFTRGGEASQT_SRKSGRRKKRGSRHA_SLRKGKE_FRDRFKL QT_IITTTVRTRGK_TQSNQSSFN_QTSIT_RGKVCGNV_DGKKAERRKRSSREG_KSGCSD_ETVFHARR_SEAISAETRTFDWK_RKD GG_S_ESNPATGAGIK_AAVVTK_IEDSSI_GRQFKRFRKADETGNKYFIGSKEIIRI_VSSAYETV_RK_RTDAGATRSA_S_AIFLDT L_NPGKGT_RRN_RKKQRKFKENTGTTK_KRNSCYSVGSSRNKS_V_AVGARPSGRTVF_IDARKQESCFKK_TRDYR_RSHC_SA_RSK QHANQRT_NIKKRE_RANRENEEGRGRI_TGEGGGDQ_S_GCL_KETQH_TNP_NTGC_QIGRNNESKRF_N__KES_YTRFEKERKGKS KAATGTQPRKREIQPDGSETSEGTE_HASAIGRRMCT_E_ASDAVGQQRE_T_AIAC_TFGPLGFYKCC_FS_C__N_W_PPRVKN_RLA FSTK_RKTQTIWLEETVCCGKQQKNFVL__RTR_GAIQSITGIGHR_TVSR_TCNPRRCV_S_N_RNS_NIPDTICK_R_M_KRCRDGTS TTS_KN_FPKSQRP_VTSYTLPLSCQL_CLCQTSLACF_ATPCPRVSKMPC_VPQRSLR_ERGLNLSM_SKL_CNISKRTAAVSMFSG_T |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_GNE_ENST00000447283_chr9_36236829_-_ROCK1_ENST00000399799_chr18_18650574_-_4741nt ATGGAGAAGAATGGAAATAACCGAAAGCTGCGGGTTTGTGTTGCTACTTGTAACCGTGCAGATTATTCTAAACTTGCCCCGATCATGTTT GGCATTAAAACCGAACCTGAGTTCTTTGAACTTGATGTTGTGGTACTTGGCTCTCACCTGATAGATGACTATGGAAATACATATCGAATG ATTGAACAAGATGACTTTGACATTAACACCAGGCTACACACAATTGTGAGGGGAGAAGATGAGGCAGCCATGGTGGAGTCAGTAGGCCTG GCCCTAGTGAAGCTGCCAGATGTCCTTAATCGCCTGAAGCCTGATATCATGATTGTTCATGGAGACAGGTTTGATGCCCTGGCTCTGGCC ACATCTGCTGCCTTGATGAACATCCGAATCCTTCACATTGAAGGTGGGGAAGTCAGTGGGACCATTGATGACTCTATCAGACATGCCATA ACAAAACTGGCTCATTATCATGTGTGCTGCACCCGCAGTGCAGAGCAGCACCTGATATCCATGTGTGAGGACCATGATCGCATCCTTTTG GCAGGCTGCCCTTCCTATGACAAACTTCTCTCAGCCAAGAACAAAGACTACATGAGCATCATTCGCATGTGGCTAGGTGATGATGTAAAA TCTAAAGATTACATTGTTGCACTACAGCACCCTGTGACCACTGACATTAAGCATTCCATAAAAATGTTTGAATTAACATTGGATGCACTT ATCTCATTTAACAAGCGGACCCTAGTCCTGTTTCCAAATATTGACGCAGGATGGATTGGATGCTTTGGTATATGATTTGGATTTTCCTGC CTTAAGAAAAAACAAAAATATTGACAACTTTTTAAGCAGATATAAAGACACAATAAATAAAATCAGAGATTTACGAATGAAAGCTGAAGA TTATGAAGTAGTGAAGGTGATTGGTAGAGGTGCATTTGGAGAAGTTCAATTGGTAAGGCATAAATCCACCAGGAAGGTATATGCTATGAA GCTTCTCAGCAAATTTGAAATGATAAAGAGATCTGATTCTGCTTTTTTCTGGGAAGAAAGGGACATCATGGCTTTTGCCAACAGTCCTTG GGTTGTTCAGCTTTTTTATGCATTCCAAGATGATCGTTATCTCTACATGGTGATGGAATACATGCCTGGTGGAGATCTTGTAAACTTAAT GAGCAACTATGATGTGCCTGAAAAATGGGCACGATTCTATACTGCAGAAGTAGTTCTTGCATTGGATGCAATCCATTCCATGGGTTTTAT TCACAGAGATGTGAAGCCTGATAACATGCTGCTGGATAAATCTGGACATTTGAAGTTAGCAGATTTTGGTACTTGTATGAAGATGAATAA GGAAGGCATGGTACGATGTGATACAGCGGTTGGAACACCTGATTATATTTCCCCTGAAGTATTAAAATCCCAAGGTGGTGATGGTTATTA TGGAAGAGAATGTGACTGGTGGTCGGTTGGGGTATTTTTATACGAAATGCTTGTAGGTGATACACCTTTTTATGCAGATTCTTTGGTTGG AACTTACAGTAAAATTATGAACCATAAAAATTCACTTACCTTTCCTGATGATAATGACATATCAAAAGAAGCAAAAAACCTTATTTGTGC CTTCCTTACTGACAGGGAAGTGAGGTTAGGGCGAAATGGTGTAGAAGAAATCAAACGACATCTCTTCTTCAAAAATGACCAGTGGGCTTG GGAAACGCTCCGAGACACTGTAGCACCAGTTGTACCCGATTTAAGTAGTGACATTGATACTAGTAATTTTGATGACTTGGAAGAAGATAA AGGAGAGGAAGAAACATTCCCTATTCCTAAAGCTTTCGTTGGCAATCAACTACCTTTTGTAGGATTTACATATTATAGCAATCGTAGATA CTTATCTTCAGCAAATCCTAATGATAACAGAACTAGCTCCAATGCAGATAAAAGCTTGCAGGAAAGTTTGCAAAAAACAATCTATAAGCT GGAAGAACAGCTGCATAATGAAATGCAGTTAAAAGATGAAATGGAGCAGAAGTGCAGAACCTCAAACATAAAACTAGACAAGATAATGAA AGAATTGGATGAAGAGGGAAATCAAAGAAGAAATCTAGAATCTACAGTGTCTCAGATTGAGAAGGAGAAAATGTTGCTACAGCATAGAAT TAATGAGTACCAAAGAAAAGCTGAACAGGAAAATGAGAAGAGAAGAAATGTAGAAAATGAAGTTTCTACATTAAAGGATCAGTTGGAAGA CTTAAAGAAAGTCAGTCAGAATTCACAGCTTGCTAATGAGAAGCTGTCCCAGTTACAAAAGCAGCTAGAAGAAGCCAATGACTTACTTAG GACAGAATCGGACACAGCTGTAAGATTGAGGAAGAGTCACACAGAGATGAGCAAGTCAATTAGTCAGTTAGAGTCCCTGAACAGAGAGTT GCAAGAGAGAAATCGAATTTTAGAGAATTCTAAGTCACAAACAGACAAAGATTATTACCAGCTGCAAGCTATATTAGAAGCTGAACGAAG AGACAGAGGTCATGATTCTGAGATGATTGGAGACCTTCAAGCTCGAATTACATCTTTACAAGAGGAGGTGAAGCATCTCAAACATAATCT CGAAAAAGTGGAAGGAGAAAGAAAAGAGGCTCAAGACATGCTTAATCACTCAGAAAAGGAAAAGAATAATTTAGAGATAGATTTAAACTA CAAACTTAAATCATTACAACAACGGTTAGAACAAGAGGTAAATGAACACAAAGTAACCAAAGCTCGTTTAACTGACAAACATCAATCTAT TGAAGAGGCAAAGTCTGTGGCAATGTGTGAGATGGAAAAAAAGCTGAAAGAAGAAAGAGAAGCTCGAGAGAAGGCTGAAAATCGGGTTGT TCAGATTGAGAAACAGTGTTCCATGCTAGACGTTGATCTGAAGCAATCTCAGCAGAAACTAGAACATTTGACTGGAAATAAAGAAAGGAT GGAGGATGAAGTTAAGAATCTAACCCTGCAACTGGAGCAGGAATCAAATAAGCGGCTGTTGTTACAAAATGAATTGAAGACTCAAGCATT TGAGGCAGACAATTTAAAAGGTTTAGAAAAGCAGATGAAACAGGAAATAAATACTTTATTGGAAGCAAAGAGATTATTAGAATTTGAGTT AGCTCAGCTTACGAAACAGTATAGAGGAAATGAAGGACAGATGCGGGAGCTACAAGATCAGCTTGAAGCTGAGCAATATTTCTCGACACT TTATAAAACCCAGGTAAAGGAACTTAAAGAAGAAATTGAAGAAAAAAACAGAGAAAATTTAAAGAAAATACAGGAACTACAAAATGAAAA AGAAACTCTTGCTACTCAGTTGGATCTAGCAGAAACAAAAGCTGAGTCTGAGCAGTTGGCGCGAGGCCTTCTGGAAGAACAGTATTTTGA ATTGACGCAAGAAAGCAAGAAAGCTGCTTCAAGAAATAGACAAGAGATTACAGATAAAGATCACACTGTTAGTCGGCTTGAAGAAGCAAA CAGCATGCTAACCAAAGATATTGAAATATTAAGAAGAGAGAATGAAGAGCTAACAGAGAAAATGAAGAAGGCAGAGGAAGAATATAAACT GGAGAAGGAGGAGGAGATCAGTAATCTTAAGGCTGCCTTTGAAAAGAATATCAACACTGAACGAACCCTTAAAACACAGGCTGTTAACAA ATTGGCAGAAATAATGAATCGAAAAGATTTTAAAATTGATAGAAAGAAAGCTAATACACAAGATTTGAGAAAGAAAGAAAAGGAAAATCG AAAGCTGCAACTGGAACTCAACCAAGAAAGAGAGAAATTCAACCAGATGGTAGTGAAACATCAGAAGGAACTGAATGACATGCAAGCGCA ATTGGTAGAAGAATGTGCACATAGGAATGAGCTTCAGATGCAGTTGGCCAGCAAAGAGAGTGATATTGAGCAATTGCGTGCTAAACTTTT GGACCTCTCGGATTCTACAAGTGTTGCTAGTTTTCCTAGTGCTGATGAAACTGATGGTAACCTCCCAGAGTCAAGAATTGAAGGTTGGCT TTCAGTACCAAATAGAGGAAATATCAAACGATATGGCTGGAAGAAACAGTATGTTGTGGTAAGCAGCAAAAAAATTTTGTTCTATAATGA CGAACAAGATAAGGAGCAATCCAATCCATCTATGGTATTGGACATAGATAAACTGTTTCACGTTAGACCTGTAACCCAAGGAGATGTGTA TAGAGCTGAAACTGAAGAAATTCCTAAAATATTCCAGATACTATATGCAAATGAAGGTGAATGTAGAAAAGATGTAGAGATGGAACCAGT ACAACAAGCTGAAAAAACTAATTTCCAAAATCACAAAGGCCATGAGTTTATTCCTACACTCTACCACTTTCCTGCCAATTGTGATGCCTG TGCCAAACCTCTCTGGCATGTTTTTAAGCCACCCCCTGCCCTAGAGTGTCGAAGATGCCATGTTAAGTGCCACAGAGATCACTTAGATAA GAAAGAGGACTTAATTTGTCCATGTAAAGTAAGTTATGATGTAACATCAGCAAGAGATATGCTGCTGTTAGCATGTTCTCAGGATGAACA AAAAAAATGGGTAACTCATTTAGTAAAGAAAATCCCTAAGAATCCACCATCTGGTTTTGTTCGTGCTTCCCCTCGAACGCTTTCTACAAG >In-frame_GNE_ENST00000377902_chr9_36236829_-_ROCK1_ENST00000399799_chr18_18650574_-_4741nt ATGGAGAAGAATGGAAATAACCGAAAGCTGCGGGTTTGTGTTGCTACTTGTAACCGTGCAGATTATTCTAAACTTGCCCCGATCATGTTT GGCATTAAAACCGAACCTGAGTTCTTTGAACTTGATGTTGTGGTACTTGGCTCTCACCTGATAGATGACTATGGAAATACATATCGAATG ATTGAACAAGATGACTTTGACATTAACACCAGGCTACACACAATTGTGAGGGGAGAAGATGAGGCAGCCATGGTGGAGTCAGTAGGCCTG GCCCTAGTGAAGCTGCCAGATGTCCTTAATCGCCTGAAGCCTGATATCATGATTGTTCATGGAGACAGGTTTGATGCCCTGGCTCTGGCC ACATCTGCTGCCTTGATGAACATCCGAATCCTTCACATTGAAGGTGGGGAAGTCAGTGGGACCATTGATGACTCTATCAGACATGCCATA ACAAAACTGGCTCATTATCATGTGTGCTGCACCCGCAGTGCAGAGCAGCACCTGATATCCATGTGTGAGGACCATGATCGCATCCTTTTG GCAGGCTGCCCTTCCTATGACAAACTTCTCTCAGCCAAGAACAAAGACTACATGAGCATCATTCGCATGTGGCTAGGTGATGATGTAAAA TCTAAAGATTACATTGTTGCACTACAGCACCCTGTGACCACTGACATTAAGCATTCCATAAAAATGTTTGAATTAACATTGGATGCACTT ATCTCATTTAACAAGCGGACCCTAGTCCTGTTTCCAAATATTGACGCAGGATGGATTGGATGCTTTGGTATATGATTTGGATTTTCCTGC CTTAAGAAAAAACAAAAATATTGACAACTTTTTAAGCAGATATAAAGACACAATAAATAAAATCAGAGATTTACGAATGAAAGCTGAAGA TTATGAAGTAGTGAAGGTGATTGGTAGAGGTGCATTTGGAGAAGTTCAATTGGTAAGGCATAAATCCACCAGGAAGGTATATGCTATGAA GCTTCTCAGCAAATTTGAAATGATAAAGAGATCTGATTCTGCTTTTTTCTGGGAAGAAAGGGACATCATGGCTTTTGCCAACAGTCCTTG GGTTGTTCAGCTTTTTTATGCATTCCAAGATGATCGTTATCTCTACATGGTGATGGAATACATGCCTGGTGGAGATCTTGTAAACTTAAT GAGCAACTATGATGTGCCTGAAAAATGGGCACGATTCTATACTGCAGAAGTAGTTCTTGCATTGGATGCAATCCATTCCATGGGTTTTAT TCACAGAGATGTGAAGCCTGATAACATGCTGCTGGATAAATCTGGACATTTGAAGTTAGCAGATTTTGGTACTTGTATGAAGATGAATAA GGAAGGCATGGTACGATGTGATACAGCGGTTGGAACACCTGATTATATTTCCCCTGAAGTATTAAAATCCCAAGGTGGTGATGGTTATTA TGGAAGAGAATGTGACTGGTGGTCGGTTGGGGTATTTTTATACGAAATGCTTGTAGGTGATACACCTTTTTATGCAGATTCTTTGGTTGG AACTTACAGTAAAATTATGAACCATAAAAATTCACTTACCTTTCCTGATGATAATGACATATCAAAAGAAGCAAAAAACCTTATTTGTGC CTTCCTTACTGACAGGGAAGTGAGGTTAGGGCGAAATGGTGTAGAAGAAATCAAACGACATCTCTTCTTCAAAAATGACCAGTGGGCTTG GGAAACGCTCCGAGACACTGTAGCACCAGTTGTACCCGATTTAAGTAGTGACATTGATACTAGTAATTTTGATGACTTGGAAGAAGATAA AGGAGAGGAAGAAACATTCCCTATTCCTAAAGCTTTCGTTGGCAATCAACTACCTTTTGTAGGATTTACATATTATAGCAATCGTAGATA CTTATCTTCAGCAAATCCTAATGATAACAGAACTAGCTCCAATGCAGATAAAAGCTTGCAGGAAAGTTTGCAAAAAACAATCTATAAGCT GGAAGAACAGCTGCATAATGAAATGCAGTTAAAAGATGAAATGGAGCAGAAGTGCAGAACCTCAAACATAAAACTAGACAAGATAATGAA AGAATTGGATGAAGAGGGAAATCAAAGAAGAAATCTAGAATCTACAGTGTCTCAGATTGAGAAGGAGAAAATGTTGCTACAGCATAGAAT TAATGAGTACCAAAGAAAAGCTGAACAGGAAAATGAGAAGAGAAGAAATGTAGAAAATGAAGTTTCTACATTAAAGGATCAGTTGGAAGA CTTAAAGAAAGTCAGTCAGAATTCACAGCTTGCTAATGAGAAGCTGTCCCAGTTACAAAAGCAGCTAGAAGAAGCCAATGACTTACTTAG GACAGAATCGGACACAGCTGTAAGATTGAGGAAGAGTCACACAGAGATGAGCAAGTCAATTAGTCAGTTAGAGTCCCTGAACAGAGAGTT GCAAGAGAGAAATCGAATTTTAGAGAATTCTAAGTCACAAACAGACAAAGATTATTACCAGCTGCAAGCTATATTAGAAGCTGAACGAAG AGACAGAGGTCATGATTCTGAGATGATTGGAGACCTTCAAGCTCGAATTACATCTTTACAAGAGGAGGTGAAGCATCTCAAACATAATCT CGAAAAAGTGGAAGGAGAAAGAAAAGAGGCTCAAGACATGCTTAATCACTCAGAAAAGGAAAAGAATAATTTAGAGATAGATTTAAACTA CAAACTTAAATCATTACAACAACGGTTAGAACAAGAGGTAAATGAACACAAAGTAACCAAAGCTCGTTTAACTGACAAACATCAATCTAT TGAAGAGGCAAAGTCTGTGGCAATGTGTGAGATGGAAAAAAAGCTGAAAGAAGAAAGAGAAGCTCGAGAGAAGGCTGAAAATCGGGTTGT TCAGATTGAGAAACAGTGTTCCATGCTAGACGTTGATCTGAAGCAATCTCAGCAGAAACTAGAACATTTGACTGGAAATAAAGAAAGGAT GGAGGATGAAGTTAAGAATCTAACCCTGCAACTGGAGCAGGAATCAAATAAGCGGCTGTTGTTACAAAATGAATTGAAGACTCAAGCATT TGAGGCAGACAATTTAAAAGGTTTAGAAAAGCAGATGAAACAGGAAATAAATACTTTATTGGAAGCAAAGAGATTATTAGAATTTGAGTT AGCTCAGCTTACGAAACAGTATAGAGGAAATGAAGGACAGATGCGGGAGCTACAAGATCAGCTTGAAGCTGAGCAATATTTCTCGACACT TTATAAAACCCAGGTAAAGGAACTTAAAGAAGAAATTGAAGAAAAAAACAGAGAAAATTTAAAGAAAATACAGGAACTACAAAATGAAAA AGAAACTCTTGCTACTCAGTTGGATCTAGCAGAAACAAAAGCTGAGTCTGAGCAGTTGGCGCGAGGCCTTCTGGAAGAACAGTATTTTGA ATTGACGCAAGAAAGCAAGAAAGCTGCTTCAAGAAATAGACAAGAGATTACAGATAAAGATCACACTGTTAGTCGGCTTGAAGAAGCAAA CAGCATGCTAACCAAAGATATTGAAATATTAAGAAGAGAGAATGAAGAGCTAACAGAGAAAATGAAGAAGGCAGAGGAAGAATATAAACT GGAGAAGGAGGAGGAGATCAGTAATCTTAAGGCTGCCTTTGAAAAGAATATCAACACTGAACGAACCCTTAAAACACAGGCTGTTAACAA ATTGGCAGAAATAATGAATCGAAAAGATTTTAAAATTGATAGAAAGAAAGCTAATACACAAGATTTGAGAAAGAAAGAAAAGGAAAATCG AAAGCTGCAACTGGAACTCAACCAAGAAAGAGAGAAATTCAACCAGATGGTAGTGAAACATCAGAAGGAACTGAATGACATGCAAGCGCA ATTGGTAGAAGAATGTGCACATAGGAATGAGCTTCAGATGCAGTTGGCCAGCAAAGAGAGTGATATTGAGCAATTGCGTGCTAAACTTTT GGACCTCTCGGATTCTACAAGTGTTGCTAGTTTTCCTAGTGCTGATGAAACTGATGGTAACCTCCCAGAGTCAAGAATTGAAGGTTGGCT TTCAGTACCAAATAGAGGAAATATCAAACGATATGGCTGGAAGAAACAGTATGTTGTGGTAAGCAGCAAAAAAATTTTGTTCTATAATGA CGAACAAGATAAGGAGCAATCCAATCCATCTATGGTATTGGACATAGATAAACTGTTTCACGTTAGACCTGTAACCCAAGGAGATGTGTA TAGAGCTGAAACTGAAGAAATTCCTAAAATATTCCAGATACTATATGCAAATGAAGGTGAATGTAGAAAAGATGTAGAGATGGAACCAGT ACAACAAGCTGAAAAAACTAATTTCCAAAATCACAAAGGCCATGAGTTTATTCCTACACTCTACCACTTTCCTGCCAATTGTGATGCCTG TGCCAAACCTCTCTGGCATGTTTTTAAGCCACCCCCTGCCCTAGAGTGTCGAAGATGCCATGTTAAGTGCCACAGAGATCACTTAGATAA GAAAGAGGACTTAATTTGTCCATGTAAAGTAAGTTATGATGTAACATCAGCAAGAGATATGCTGCTGTTAGCATGTTCTCAGGATGAACA AAAAAAATGGGTAACTCATTTAGTAAAGAAAATCCCTAAGAATCCACCATCTGGTTTTGTTCGTGCTTCCCCTCGAACGCTTTCTACAAG |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_GNE_ENST00000447283_chr9_36236829_-_ROCK1_ENST00000399799_chr18_18650574_-_9270nt CGGCGTCTGGAACTCTATTTTAAGAACCTCTCAAAACGAAACAAGCAAATCATGGAGAAGAATGGAAATAACCGAAAGCTGCGGGTTTGT GTTGCTACTTGTAACCGTGCAGATTATTCTAAACTTGCCCCGATCATGTTTGGCATTAAAACCGAACCTGAGTTCTTTGAACTTGATGTT GTGGTACTTGGCTCTCACCTGATAGATGACTATGGAAATACATATCGAATGATTGAACAAGATGACTTTGACATTAACACCAGGCTACAC ACAATTGTGAGGGGAGAAGATGAGGCAGCCATGGTGGAGTCAGTAGGCCTGGCCCTAGTGAAGCTGCCAGATGTCCTTAATCGCCTGAAG CCTGATATCATGATTGTTCATGGAGACAGGTTTGATGCCCTGGCTCTGGCCACATCTGCTGCCTTGATGAACATCCGAATCCTTCACATT GAAGGTGGGGAAGTCAGTGGGACCATTGATGACTCTATCAGACATGCCATAACAAAACTGGCTCATTATCATGTGTGCTGCACCCGCAGT GCAGAGCAGCACCTGATATCCATGTGTGAGGACCATGATCGCATCCTTTTGGCAGGCTGCCCTTCCTATGACAAACTTCTCTCAGCCAAG AACAAAGACTACATGAGCATCATTCGCATGTGGCTAGGTGATGATGTAAAATCTAAAGATTACATTGTTGCACTACAGCACCCTGTGACC ACTGACATTAAGCATTCCATAAAAATGTTTGAATTAACATTGGATGCACTTATCTCATTTAACAAGCGGACCCTAGTCCTGTTTCCAAAT ATTGACGCAGGATGGATTGGATGCTTTGGTATATGATTTGGATTTTCCTGCCTTAAGAAAAAACAAAAATATTGACAACTTTTTAAGCAG ATATAAAGACACAATAAATAAAATCAGAGATTTACGAATGAAAGCTGAAGATTATGAAGTAGTGAAGGTGATTGGTAGAGGTGCATTTGG AGAAGTTCAATTGGTAAGGCATAAATCCACCAGGAAGGTATATGCTATGAAGCTTCTCAGCAAATTTGAAATGATAAAGAGATCTGATTC TGCTTTTTTCTGGGAAGAAAGGGACATCATGGCTTTTGCCAACAGTCCTTGGGTTGTTCAGCTTTTTTATGCATTCCAAGATGATCGTTA TCTCTACATGGTGATGGAATACATGCCTGGTGGAGATCTTGTAAACTTAATGAGCAACTATGATGTGCCTGAAAAATGGGCACGATTCTA TACTGCAGAAGTAGTTCTTGCATTGGATGCAATCCATTCCATGGGTTTTATTCACAGAGATGTGAAGCCTGATAACATGCTGCTGGATAA ATCTGGACATTTGAAGTTAGCAGATTTTGGTACTTGTATGAAGATGAATAAGGAAGGCATGGTACGATGTGATACAGCGGTTGGAACACC TGATTATATTTCCCCTGAAGTATTAAAATCCCAAGGTGGTGATGGTTATTATGGAAGAGAATGTGACTGGTGGTCGGTTGGGGTATTTTT ATACGAAATGCTTGTAGGTGATACACCTTTTTATGCAGATTCTTTGGTTGGAACTTACAGTAAAATTATGAACCATAAAAATTCACTTAC CTTTCCTGATGATAATGACATATCAAAAGAAGCAAAAAACCTTATTTGTGCCTTCCTTACTGACAGGGAAGTGAGGTTAGGGCGAAATGG TGTAGAAGAAATCAAACGACATCTCTTCTTCAAAAATGACCAGTGGGCTTGGGAAACGCTCCGAGACACTGTAGCACCAGTTGTACCCGA TTTAAGTAGTGACATTGATACTAGTAATTTTGATGACTTGGAAGAAGATAAAGGAGAGGAAGAAACATTCCCTATTCCTAAAGCTTTCGT TGGCAATCAACTACCTTTTGTAGGATTTACATATTATAGCAATCGTAGATACTTATCTTCAGCAAATCCTAATGATAACAGAACTAGCTC CAATGCAGATAAAAGCTTGCAGGAAAGTTTGCAAAAAACAATCTATAAGCTGGAAGAACAGCTGCATAATGAAATGCAGTTAAAAGATGA AATGGAGCAGAAGTGCAGAACCTCAAACATAAAACTAGACAAGATAATGAAAGAATTGGATGAAGAGGGAAATCAAAGAAGAAATCTAGA ATCTACAGTGTCTCAGATTGAGAAGGAGAAAATGTTGCTACAGCATAGAATTAATGAGTACCAAAGAAAAGCTGAACAGGAAAATGAGAA GAGAAGAAATGTAGAAAATGAAGTTTCTACATTAAAGGATCAGTTGGAAGACTTAAAGAAAGTCAGTCAGAATTCACAGCTTGCTAATGA GAAGCTGTCCCAGTTACAAAAGCAGCTAGAAGAAGCCAATGACTTACTTAGGACAGAATCGGACACAGCTGTAAGATTGAGGAAGAGTCA CACAGAGATGAGCAAGTCAATTAGTCAGTTAGAGTCCCTGAACAGAGAGTTGCAAGAGAGAAATCGAATTTTAGAGAATTCTAAGTCACA AACAGACAAAGATTATTACCAGCTGCAAGCTATATTAGAAGCTGAACGAAGAGACAGAGGTCATGATTCTGAGATGATTGGAGACCTTCA AGCTCGAATTACATCTTTACAAGAGGAGGTGAAGCATCTCAAACATAATCTCGAAAAAGTGGAAGGAGAAAGAAAAGAGGCTCAAGACAT GCTTAATCACTCAGAAAAGGAAAAGAATAATTTAGAGATAGATTTAAACTACAAACTTAAATCATTACAACAACGGTTAGAACAAGAGGT AAATGAACACAAAGTAACCAAAGCTCGTTTAACTGACAAACATCAATCTATTGAAGAGGCAAAGTCTGTGGCAATGTGTGAGATGGAAAA AAAGCTGAAAGAAGAAAGAGAAGCTCGAGAGAAGGCTGAAAATCGGGTTGTTCAGATTGAGAAACAGTGTTCCATGCTAGACGTTGATCT GAAGCAATCTCAGCAGAAACTAGAACATTTGACTGGAAATAAAGAAAGGATGGAGGATGAAGTTAAGAATCTAACCCTGCAACTGGAGCA GGAATCAAATAAGCGGCTGTTGTTACAAAATGAATTGAAGACTCAAGCATTTGAGGCAGACAATTTAAAAGGTTTAGAAAAGCAGATGAA ACAGGAAATAAATACTTTATTGGAAGCAAAGAGATTATTAGAATTTGAGTTAGCTCAGCTTACGAAACAGTATAGAGGAAATGAAGGACA GATGCGGGAGCTACAAGATCAGCTTGAAGCTGAGCAATATTTCTCGACACTTTATAAAACCCAGGTAAAGGAACTTAAAGAAGAAATTGA AGAAAAAAACAGAGAAAATTTAAAGAAAATACAGGAACTACAAAATGAAAAAGAAACTCTTGCTACTCAGTTGGATCTAGCAGAAACAAA AGCTGAGTCTGAGCAGTTGGCGCGAGGCCTTCTGGAAGAACAGTATTTTGAATTGACGCAAGAAAGCAAGAAAGCTGCTTCAAGAAATAG ACAAGAGATTACAGATAAAGATCACACTGTTAGTCGGCTTGAAGAAGCAAACAGCATGCTAACCAAAGATATTGAAATATTAAGAAGAGA GAATGAAGAGCTAACAGAGAAAATGAAGAAGGCAGAGGAAGAATATAAACTGGAGAAGGAGGAGGAGATCAGTAATCTTAAGGCTGCCTT TGAAAAGAATATCAACACTGAACGAACCCTTAAAACACAGGCTGTTAACAAATTGGCAGAAATAATGAATCGAAAAGATTTTAAAATTGA TAGAAAGAAAGCTAATACACAAGATTTGAGAAAGAAAGAAAAGGAAAATCGAAAGCTGCAACTGGAACTCAACCAAGAAAGAGAGAAATT CAACCAGATGGTAGTGAAACATCAGAAGGAACTGAATGACATGCAAGCGCAATTGGTAGAAGAATGTGCACATAGGAATGAGCTTCAGAT GCAGTTGGCCAGCAAAGAGAGTGATATTGAGCAATTGCGTGCTAAACTTTTGGACCTCTCGGATTCTACAAGTGTTGCTAGTTTTCCTAG TGCTGATGAAACTGATGGTAACCTCCCAGAGTCAAGAATTGAAGGTTGGCTTTCAGTACCAAATAGAGGAAATATCAAACGATATGGCTG GAAGAAACAGTATGTTGTGGTAAGCAGCAAAAAAATTTTGTTCTATAATGACGAACAAGATAAGGAGCAATCCAATCCATCTATGGTATT GGACATAGATAAACTGTTTCACGTTAGACCTGTAACCCAAGGAGATGTGTATAGAGCTGAAACTGAAGAAATTCCTAAAATATTCCAGAT ACTATATGCAAATGAAGGTGAATGTAGAAAAGATGTAGAGATGGAACCAGTACAACAAGCTGAAAAAACTAATTTCCAAAATCACAAAGG CCATGAGTTTATTCCTACACTCTACCACTTTCCTGCCAATTGTGATGCCTGTGCCAAACCTCTCTGGCATGTTTTTAAGCCACCCCCTGC CCTAGAGTGTCGAAGATGCCATGTTAAGTGCCACAGAGATCACTTAGATAAGAAAGAGGACTTAATTTGTCCATGTAAAGTAAGTTATGA TGTAACATCAGCAAGAGATATGCTGCTGTTAGCATGTTCTCAGGATGAACAAAAAAAATGGGTAACTCATTTAGTAAAGAAAATCCCTAA GAATCCACCATCTGGTTTTGTTCGTGCTTCCCCTCGAACGCTTTCTACAAGATCCACTGCAAATCAGTCTTTCCGGAAAGTGGTCAAAAA TACATCTGGAAAAACTAGTTAACCATGTGACTGAGTGCCCTGTGGAATCGTGTGGGATGCTACCTGATAAACCAGGCTTCTTTAACCATG CAGAGCAGACAGGCTGTTTCTTTGACACAAATATCACAGGCTTCAGGGTTAAGATTGCTGTTTTTCTGTCCTTGCTTTGGCACAACACAC TGAGGGTTTTTTTTATTGCGGGTTTGCCTACAGGTAGATTAGATTAATTATTACTATGTAATGCAAGTACAGTTGGGGGAAAGCTTAGGT AGATATATTTTTTTTAAAAGGTGCTGCCTTTTTGGATTTATAAGAAAATGCCTGTCAGTCGTGATAGAACAGAGTTTTCCTCATATGAGT AAGAGGAAGGGACTTTCACTTTCAAGTGGAACAGCCATCACTATCAAGATCAGCTCATGGAAGGAGTAAAGAAAATATCTCAAAATGAGA CAAACTGAAGTTTTGTTTTTTTTTTAATGACTTAAGTTTTTGTGCTCTTGCAAGACTATACAAAACTATTTTAAGAAAGCAGTGATATCA CTTGAACTTCAGTGCCCTCACTGTAGAATTTAAAAGCCTTACTGTTGATTGCCCATGTTGGACTTGATGGAGAAATTAAATATCTTTCAT TATGCTTTACAAAATACTGTATATGTTTCAGCAAGTTTGGGGAATGGGAGAGGACAAAAAAAAGTTACATTTAATCTATGCATTTTTGCC AAGCCATATTGAGTTATTTTACTACTAGAGACATTAGGAAACTAACTGTACAAAAGAACCAAGTTTAAAAGCATTTTGTGGGGTACATCA TTTCTATAATTGTATAATGTATTTCTTTGTGGTTTTAAATGATAAAGACATTAAGTTAACAAACATATAAGAAATGTATGCACTGTTTGA AATGTAAATTATTCTTAGAACACTTTCAATGGGGGTTGCATTGTCCTTTTAGTGCCTTAATTTGAGATAATTATTTTACTGCCATGAGTA AGTATAGAAATTTCAAAAAATGTATTTTCAAAAAATTATGTGTGTCAGTGAGTTTTTCATTGATAATTGGTTTAATTTAAAATATTTAGA GGTTTGTTGGACTTTCATAAATTGAGTACAATCTTTGCATCAAACTACCTGCTACAATAATGACTTTATAAAACTGCAAAAAATGTAGAA GGTTGCACCAACATAAAAAGGAAATATGGCAATACATCCATGATGTTTTCCAGTTAACATAGGAATTACCAGATAAATACTGTTAAACTC TTGTCCAGTAACAAGAGTTGATTCATATGGACAGTATGATTTATTGTTTATTTTTTTAACCAAATACCTCCTCAGTAATTTATAATGGCT TTGCAGTAATGTGTATCAGATAAGAAGCACTGGAAAACCGATCGTCTCTAGGATGATATGCATGTTTCAAGTGGTATTGAAAGCCGCACT GATGGATATGTAATAATAAACATATCTGTTATTAATATACTAATGACTCTGTGCTCATTTAATGAGAAATAAAAGTAATTTATGGATGGG TATCTTTAATTTTTACTGCAATGTGTTTTCTCATGGCTGAAATGAATGGAAAACATACTTCAAATTAGTCTCTGATTGTATATAAATGTT TGTGAAATTCCATGGTTAGATTAAAGTGTATTTTTAAAAGATAAAACGTGGTCTTGGGCTCTAAAACAAGAGTGGGAATAGTTCACATGA AAAGCTGGCTAAAGTGTGTTGGAAAACAATTCTCCATGGGTCTCTTGCATTTCTACACATCAGGGAAGCAGAGGCTCTGACAACCTTTCT TTTGACTATCTTTTCCAAGGATATTTATGTAGTAAACAGCCTTGGAAGATAGAGTTCTCCCTTGTGAGGATGTCGGGTTCTTTTACTGTC CAGTATAATAAAGATAACGTCTCCCACCTATGATGCAAACCCACTGTGTGCTCAGCACCCACCTGGGCCACTCTGCATTGCCCACATGGG GCTTGGAGGGCAAAGGGAACTGATGGAACGTGAAACTTATGCTGCTTTTGCTGTGCTGTGAATGAAGTCATCTGACTCTGACCCAGGGGT CTCATCTCTTTTGTCAGGATCCATGAAACTGTGACTGGCAGCATGCAAACAGGATAAAATCTCAGCACAGTTCCTGACGGTGTCCTTACT ACCTTCTCAGACTCATCACCATTACCTAATATTTTAAGGTCCAGTTGCAGAGAACAGAGTTAATTCTAATTAGTTTAAGCAAGAGAAGAC TTTCCAAATGACATACTAATCTGAACTTAGAATTGTTGAGAACTGAGAGAGCTTTGAGGAATCACTCCCAATGCCACATTACAGAACTGG GTCAACCAGGAGAGCTGCTTCCTCTTCTAAGTTCAGGAAACCACTCACTCCCAAGTATACCAATATTGAGAGGGTCCAGATAGTGCCATA ATCAGGAATCCACACTACCACTGCTGGTTCTCTGCAACACTTGTCAGGCTTGCTACAATCTACCTCCAGTTAGATGTTTTGTACCATTCC TCTTGCCACTTAAGAACCTCATGTCTGCACACTGCCTCAGAAAAGGCACTTCCATGACCCTGCTTGCTGGCATTTAGCACAGCCTGCATC TCACGTCTGCCTTCTCTAGGTGCATCTACGTGGCCAAAATTAAATCACATCCAGACCCCTAGCTGCAAGAAAGTCTGAGAAATATAGCCT CTAGCTTTCTCTCTAATTTGTTACAGGAGGACACACTAGGAGTGTGGAATGAAGGTTCAGCATTGAGTTAGCCCATGCACCCACACCTGT AAGCTTCTCTGAGATCAGGAACTCCAGCTTTGGGCAACAAAGAAAACATAGCCACTGTCATTATTCACAGGTTCACTCATGACCTGTCAT TTGGGGTTTCAGCTTAAATTAACCCATTCACCCTTCATTTAAAGTAAAAAAAATAAGTAAAAGAACTTAAATGACAAACTCATAGTTACT TGAGTTTGTAATTCATAGTTAACTTTCACAGTTCTATAATCAATCTGGAATTCAGAGTGAGGTAGAGATCAAGCAGTATTTCTCCCATAT GGATATTCAGTTGATACTGCAGTATTCATTGAAAATACTTCTTTCCTGCATCGTAATTCAGGTGAACAATCCATTGGTGTTATTTCTGTG TCCTTGCCAATATCACACTTTTAATTACTGTAACTTTATAATAAGATTTTATATCTGTAGTAGAAGTCCAACTTTGTAATCCCTCCCAAT TGGCTTGGCTATTCTTGGCCTTTTGCATTTCCATATAATTTTTTATTTTTGTTTTGAAACGAAGTTTCGCTCTTGTTGCCCAGGCTGGAG TGCAGTGGCGCGATCTCGGCTCACTGCAACCTCCGCCTCCCAGGTTCAAGTGATCCTCCTGCCTCAGACTCCCGAGTAGCTGGGATTACA GGTGCCCACCACCATGCCCAGCTAATTTTTGTATTTTTAGTAGAGACAGGGTTTCACCATGTTGGCCAGCCTGGTCTTGAACTCCTGACC TCAGGTGATCCACACCCACCTTGGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACCGCGCCTGGTTGCATTCCCATATAAATTTAA AAACAATCTACTGAAAGATGTATACGACCTCCACCAAGAAAATTGTAAGACATTTGGAGAAGTTTAAAAAGACATGAATAAACGGAAATG GTTTTTTTAAATAAACAAATGATTTTTAAAGTTGATCATTAGGTTAATAAATAGTCATATAATGACAATCCGATGAGATTATGTTGCCCA GGGTGGTCTCTAACTCCTAGCCTCAAGCAGTTTTACTCTCTCATTACAGGTGTAGGCCACCGTGCCTGGCCTGACACTTGGAAATCTTAA TCACAATTATTCTTTGTTTTTATAATGTTTACTGTTCAAATCAATTTCTGGTTGGATAGTATGTATATATAAAGCCATGCTCAATGGCCT AGATATATTTACTGCCAAATCTTTTATGCTTTTAGTGTTTTTTTTCTGGACAAGATCTATGCTTATTGCAATAAATTAAATGCAAAGAAT ATTCTAGTAGAAAGTCAGTCTGCACTTCCTAAACCCCACCCCACCCCACCAATTCCTTCATAACTGTTATTAACAGTTAGCTGTGTTTTC TAATGGATTATCTCCAAAGTATATGTAACTCAGATTTTTGTGAGGTAGGAAAAGAATAACATTAATTCCACTTCACATATTGAAAGTCTA ACATACAAAGAGATTAAATATCTCCTTTCTTTTGCCAAATGTTAATGAATTGTCTTATGAGAATTAAGATATGATACTTTCTCCCAAGCT ATACTGTTTCCCATAAAGTATTTGAGATGTTGGAGATTCAAGGGAAAAAATATAAATGCTTAGAAATAAAGTGTATAATGCAAAGATTGT GAATAAAGTGACACTTGTATGTTAATCCTATAAATTGGTTTCTTGTACCATGTAGGATGGTTTGGCTATTAAATTGAATTAAGTGGTTCA >In-frame_GNE_ENST00000377902_chr9_36236829_-_ROCK1_ENST00000399799_chr18_18650574_-_9440nt GTGGGCGTGGCTGGGCGAGCGAGGAGTGGGGACAAGGTCGAGCGACGAGTCGTCTACCCGCGCGCCCGAGCGCGGAAACCGAGGGGCAGG CTCGCGCTCTGCCTGCTTCGTGGCGCTTGGTTCGTCCCTCGCCCGAGGAGCGCGGTGGCGGCGTGGGAGGGAGCCTCTGACGGCGTCTGG AACTCTATTTTAAGAACCTCTCAAAACGAAACAAGCAAATCATGGAGAAGAATGGAAATAACCGAAAGCTGCGGGTTTGTGTTGCTACTT GTAACCGTGCAGATTATTCTAAACTTGCCCCGATCATGTTTGGCATTAAAACCGAACCTGAGTTCTTTGAACTTGATGTTGTGGTACTTG GCTCTCACCTGATAGATGACTATGGAAATACATATCGAATGATTGAACAAGATGACTTTGACATTAACACCAGGCTACACACAATTGTGA GGGGAGAAGATGAGGCAGCCATGGTGGAGTCAGTAGGCCTGGCCCTAGTGAAGCTGCCAGATGTCCTTAATCGCCTGAAGCCTGATATCA TGATTGTTCATGGAGACAGGTTTGATGCCCTGGCTCTGGCCACATCTGCTGCCTTGATGAACATCCGAATCCTTCACATTGAAGGTGGGG AAGTCAGTGGGACCATTGATGACTCTATCAGACATGCCATAACAAAACTGGCTCATTATCATGTGTGCTGCACCCGCAGTGCAGAGCAGC ACCTGATATCCATGTGTGAGGACCATGATCGCATCCTTTTGGCAGGCTGCCCTTCCTATGACAAACTTCTCTCAGCCAAGAACAAAGACT ACATGAGCATCATTCGCATGTGGCTAGGTGATGATGTAAAATCTAAAGATTACATTGTTGCACTACAGCACCCTGTGACCACTGACATTA AGCATTCCATAAAAATGTTTGAATTAACATTGGATGCACTTATCTCATTTAACAAGCGGACCCTAGTCCTGTTTCCAAATATTGACGCAG GATGGATTGGATGCTTTGGTATATGATTTGGATTTTCCTGCCTTAAGAAAAAACAAAAATATTGACAACTTTTTAAGCAGATATAAAGAC ACAATAAATAAAATCAGAGATTTACGAATGAAAGCTGAAGATTATGAAGTAGTGAAGGTGATTGGTAGAGGTGCATTTGGAGAAGTTCAA TTGGTAAGGCATAAATCCACCAGGAAGGTATATGCTATGAAGCTTCTCAGCAAATTTGAAATGATAAAGAGATCTGATTCTGCTTTTTTC TGGGAAGAAAGGGACATCATGGCTTTTGCCAACAGTCCTTGGGTTGTTCAGCTTTTTTATGCATTCCAAGATGATCGTTATCTCTACATG GTGATGGAATACATGCCTGGTGGAGATCTTGTAAACTTAATGAGCAACTATGATGTGCCTGAAAAATGGGCACGATTCTATACTGCAGAA GTAGTTCTTGCATTGGATGCAATCCATTCCATGGGTTTTATTCACAGAGATGTGAAGCCTGATAACATGCTGCTGGATAAATCTGGACAT TTGAAGTTAGCAGATTTTGGTACTTGTATGAAGATGAATAAGGAAGGCATGGTACGATGTGATACAGCGGTTGGAACACCTGATTATATT TCCCCTGAAGTATTAAAATCCCAAGGTGGTGATGGTTATTATGGAAGAGAATGTGACTGGTGGTCGGTTGGGGTATTTTTATACGAAATG CTTGTAGGTGATACACCTTTTTATGCAGATTCTTTGGTTGGAACTTACAGTAAAATTATGAACCATAAAAATTCACTTACCTTTCCTGAT GATAATGACATATCAAAAGAAGCAAAAAACCTTATTTGTGCCTTCCTTACTGACAGGGAAGTGAGGTTAGGGCGAAATGGTGTAGAAGAA ATCAAACGACATCTCTTCTTCAAAAATGACCAGTGGGCTTGGGAAACGCTCCGAGACACTGTAGCACCAGTTGTACCCGATTTAAGTAGT GACATTGATACTAGTAATTTTGATGACTTGGAAGAAGATAAAGGAGAGGAAGAAACATTCCCTATTCCTAAAGCTTTCGTTGGCAATCAA CTACCTTTTGTAGGATTTACATATTATAGCAATCGTAGATACTTATCTTCAGCAAATCCTAATGATAACAGAACTAGCTCCAATGCAGAT AAAAGCTTGCAGGAAAGTTTGCAAAAAACAATCTATAAGCTGGAAGAACAGCTGCATAATGAAATGCAGTTAAAAGATGAAATGGAGCAG AAGTGCAGAACCTCAAACATAAAACTAGACAAGATAATGAAAGAATTGGATGAAGAGGGAAATCAAAGAAGAAATCTAGAATCTACAGTG TCTCAGATTGAGAAGGAGAAAATGTTGCTACAGCATAGAATTAATGAGTACCAAAGAAAAGCTGAACAGGAAAATGAGAAGAGAAGAAAT GTAGAAAATGAAGTTTCTACATTAAAGGATCAGTTGGAAGACTTAAAGAAAGTCAGTCAGAATTCACAGCTTGCTAATGAGAAGCTGTCC CAGTTACAAAAGCAGCTAGAAGAAGCCAATGACTTACTTAGGACAGAATCGGACACAGCTGTAAGATTGAGGAAGAGTCACACAGAGATG AGCAAGTCAATTAGTCAGTTAGAGTCCCTGAACAGAGAGTTGCAAGAGAGAAATCGAATTTTAGAGAATTCTAAGTCACAAACAGACAAA GATTATTACCAGCTGCAAGCTATATTAGAAGCTGAACGAAGAGACAGAGGTCATGATTCTGAGATGATTGGAGACCTTCAAGCTCGAATT ACATCTTTACAAGAGGAGGTGAAGCATCTCAAACATAATCTCGAAAAAGTGGAAGGAGAAAGAAAAGAGGCTCAAGACATGCTTAATCAC TCAGAAAAGGAAAAGAATAATTTAGAGATAGATTTAAACTACAAACTTAAATCATTACAACAACGGTTAGAACAAGAGGTAAATGAACAC AAAGTAACCAAAGCTCGTTTAACTGACAAACATCAATCTATTGAAGAGGCAAAGTCTGTGGCAATGTGTGAGATGGAAAAAAAGCTGAAA GAAGAAAGAGAAGCTCGAGAGAAGGCTGAAAATCGGGTTGTTCAGATTGAGAAACAGTGTTCCATGCTAGACGTTGATCTGAAGCAATCT CAGCAGAAACTAGAACATTTGACTGGAAATAAAGAAAGGATGGAGGATGAAGTTAAGAATCTAACCCTGCAACTGGAGCAGGAATCAAAT AAGCGGCTGTTGTTACAAAATGAATTGAAGACTCAAGCATTTGAGGCAGACAATTTAAAAGGTTTAGAAAAGCAGATGAAACAGGAAATA AATACTTTATTGGAAGCAAAGAGATTATTAGAATTTGAGTTAGCTCAGCTTACGAAACAGTATAGAGGAAATGAAGGACAGATGCGGGAG CTACAAGATCAGCTTGAAGCTGAGCAATATTTCTCGACACTTTATAAAACCCAGGTAAAGGAACTTAAAGAAGAAATTGAAGAAAAAAAC AGAGAAAATTTAAAGAAAATACAGGAACTACAAAATGAAAAAGAAACTCTTGCTACTCAGTTGGATCTAGCAGAAACAAAAGCTGAGTCT GAGCAGTTGGCGCGAGGCCTTCTGGAAGAACAGTATTTTGAATTGACGCAAGAAAGCAAGAAAGCTGCTTCAAGAAATAGACAAGAGATT ACAGATAAAGATCACACTGTTAGTCGGCTTGAAGAAGCAAACAGCATGCTAACCAAAGATATTGAAATATTAAGAAGAGAGAATGAAGAG CTAACAGAGAAAATGAAGAAGGCAGAGGAAGAATATAAACTGGAGAAGGAGGAGGAGATCAGTAATCTTAAGGCTGCCTTTGAAAAGAAT ATCAACACTGAACGAACCCTTAAAACACAGGCTGTTAACAAATTGGCAGAAATAATGAATCGAAAAGATTTTAAAATTGATAGAAAGAAA GCTAATACACAAGATTTGAGAAAGAAAGAAAAGGAAAATCGAAAGCTGCAACTGGAACTCAACCAAGAAAGAGAGAAATTCAACCAGATG GTAGTGAAACATCAGAAGGAACTGAATGACATGCAAGCGCAATTGGTAGAAGAATGTGCACATAGGAATGAGCTTCAGATGCAGTTGGCC AGCAAAGAGAGTGATATTGAGCAATTGCGTGCTAAACTTTTGGACCTCTCGGATTCTACAAGTGTTGCTAGTTTTCCTAGTGCTGATGAA ACTGATGGTAACCTCCCAGAGTCAAGAATTGAAGGTTGGCTTTCAGTACCAAATAGAGGAAATATCAAACGATATGGCTGGAAGAAACAG TATGTTGTGGTAAGCAGCAAAAAAATTTTGTTCTATAATGACGAACAAGATAAGGAGCAATCCAATCCATCTATGGTATTGGACATAGAT AAACTGTTTCACGTTAGACCTGTAACCCAAGGAGATGTGTATAGAGCTGAAACTGAAGAAATTCCTAAAATATTCCAGATACTATATGCA AATGAAGGTGAATGTAGAAAAGATGTAGAGATGGAACCAGTACAACAAGCTGAAAAAACTAATTTCCAAAATCACAAAGGCCATGAGTTT ATTCCTACACTCTACCACTTTCCTGCCAATTGTGATGCCTGTGCCAAACCTCTCTGGCATGTTTTTAAGCCACCCCCTGCCCTAGAGTGT CGAAGATGCCATGTTAAGTGCCACAGAGATCACTTAGATAAGAAAGAGGACTTAATTTGTCCATGTAAAGTAAGTTATGATGTAACATCA GCAAGAGATATGCTGCTGTTAGCATGTTCTCAGGATGAACAAAAAAAATGGGTAACTCATTTAGTAAAGAAAATCCCTAAGAATCCACCA TCTGGTTTTGTTCGTGCTTCCCCTCGAACGCTTTCTACAAGATCCACTGCAAATCAGTCTTTCCGGAAAGTGGTCAAAAATACATCTGGA AAAACTAGTTAACCATGTGACTGAGTGCCCTGTGGAATCGTGTGGGATGCTACCTGATAAACCAGGCTTCTTTAACCATGCAGAGCAGAC AGGCTGTTTCTTTGACACAAATATCACAGGCTTCAGGGTTAAGATTGCTGTTTTTCTGTCCTTGCTTTGGCACAACACACTGAGGGTTTT TTTTATTGCGGGTTTGCCTACAGGTAGATTAGATTAATTATTACTATGTAATGCAAGTACAGTTGGGGGAAAGCTTAGGTAGATATATTT TTTTTAAAAGGTGCTGCCTTTTTGGATTTATAAGAAAATGCCTGTCAGTCGTGATAGAACAGAGTTTTCCTCATATGAGTAAGAGGAAGG GACTTTCACTTTCAAGTGGAACAGCCATCACTATCAAGATCAGCTCATGGAAGGAGTAAAGAAAATATCTCAAAATGAGACAAACTGAAG TTTTGTTTTTTTTTTAATGACTTAAGTTTTTGTGCTCTTGCAAGACTATACAAAACTATTTTAAGAAAGCAGTGATATCACTTGAACTTC AGTGCCCTCACTGTAGAATTTAAAAGCCTTACTGTTGATTGCCCATGTTGGACTTGATGGAGAAATTAAATATCTTTCATTATGCTTTAC AAAATACTGTATATGTTTCAGCAAGTTTGGGGAATGGGAGAGGACAAAAAAAAGTTACATTTAATCTATGCATTTTTGCCAAGCCATATT GAGTTATTTTACTACTAGAGACATTAGGAAACTAACTGTACAAAAGAACCAAGTTTAAAAGCATTTTGTGGGGTACATCATTTCTATAAT TGTATAATGTATTTCTTTGTGGTTTTAAATGATAAAGACATTAAGTTAACAAACATATAAGAAATGTATGCACTGTTTGAAATGTAAATT ATTCTTAGAACACTTTCAATGGGGGTTGCATTGTCCTTTTAGTGCCTTAATTTGAGATAATTATTTTACTGCCATGAGTAAGTATAGAAA TTTCAAAAAATGTATTTTCAAAAAATTATGTGTGTCAGTGAGTTTTTCATTGATAATTGGTTTAATTTAAAATATTTAGAGGTTTGTTGG ACTTTCATAAATTGAGTACAATCTTTGCATCAAACTACCTGCTACAATAATGACTTTATAAAACTGCAAAAAATGTAGAAGGTTGCACCA ACATAAAAAGGAAATATGGCAATACATCCATGATGTTTTCCAGTTAACATAGGAATTACCAGATAAATACTGTTAAACTCTTGTCCAGTA ACAAGAGTTGATTCATATGGACAGTATGATTTATTGTTTATTTTTTTAACCAAATACCTCCTCAGTAATTTATAATGGCTTTGCAGTAAT GTGTATCAGATAAGAAGCACTGGAAAACCGATCGTCTCTAGGATGATATGCATGTTTCAAGTGGTATTGAAAGCCGCACTGATGGATATG TAATAATAAACATATCTGTTATTAATATACTAATGACTCTGTGCTCATTTAATGAGAAATAAAAGTAATTTATGGATGGGTATCTTTAAT TTTTACTGCAATGTGTTTTCTCATGGCTGAAATGAATGGAAAACATACTTCAAATTAGTCTCTGATTGTATATAAATGTTTGTGAAATTC CATGGTTAGATTAAAGTGTATTTTTAAAAGATAAAACGTGGTCTTGGGCTCTAAAACAAGAGTGGGAATAGTTCACATGAAAAGCTGGCT AAAGTGTGTTGGAAAACAATTCTCCATGGGTCTCTTGCATTTCTACACATCAGGGAAGCAGAGGCTCTGACAACCTTTCTTTTGACTATC TTTTCCAAGGATATTTATGTAGTAAACAGCCTTGGAAGATAGAGTTCTCCCTTGTGAGGATGTCGGGTTCTTTTACTGTCCAGTATAATA AAGATAACGTCTCCCACCTATGATGCAAACCCACTGTGTGCTCAGCACCCACCTGGGCCACTCTGCATTGCCCACATGGGGCTTGGAGGG CAAAGGGAACTGATGGAACGTGAAACTTATGCTGCTTTTGCTGTGCTGTGAATGAAGTCATCTGACTCTGACCCAGGGGTCTCATCTCTT TTGTCAGGATCCATGAAACTGTGACTGGCAGCATGCAAACAGGATAAAATCTCAGCACAGTTCCTGACGGTGTCCTTACTACCTTCTCAG ACTCATCACCATTACCTAATATTTTAAGGTCCAGTTGCAGAGAACAGAGTTAATTCTAATTAGTTTAAGCAAGAGAAGACTTTCCAAATG ACATACTAATCTGAACTTAGAATTGTTGAGAACTGAGAGAGCTTTGAGGAATCACTCCCAATGCCACATTACAGAACTGGGTCAACCAGG AGAGCTGCTTCCTCTTCTAAGTTCAGGAAACCACTCACTCCCAAGTATACCAATATTGAGAGGGTCCAGATAGTGCCATAATCAGGAATC CACACTACCACTGCTGGTTCTCTGCAACACTTGTCAGGCTTGCTACAATCTACCTCCAGTTAGATGTTTTGTACCATTCCTCTTGCCACT TAAGAACCTCATGTCTGCACACTGCCTCAGAAAAGGCACTTCCATGACCCTGCTTGCTGGCATTTAGCACAGCCTGCATCTCACGTCTGC CTTCTCTAGGTGCATCTACGTGGCCAAAATTAAATCACATCCAGACCCCTAGCTGCAAGAAAGTCTGAGAAATATAGCCTCTAGCTTTCT CTCTAATTTGTTACAGGAGGACACACTAGGAGTGTGGAATGAAGGTTCAGCATTGAGTTAGCCCATGCACCCACACCTGTAAGCTTCTCT GAGATCAGGAACTCCAGCTTTGGGCAACAAAGAAAACATAGCCACTGTCATTATTCACAGGTTCACTCATGACCTGTCATTTGGGGTTTC AGCTTAAATTAACCCATTCACCCTTCATTTAAAGTAAAAAAAATAAGTAAAAGAACTTAAATGACAAACTCATAGTTACTTGAGTTTGTA ATTCATAGTTAACTTTCACAGTTCTATAATCAATCTGGAATTCAGAGTGAGGTAGAGATCAAGCAGTATTTCTCCCATATGGATATTCAG TTGATACTGCAGTATTCATTGAAAATACTTCTTTCCTGCATCGTAATTCAGGTGAACAATCCATTGGTGTTATTTCTGTGTCCTTGCCAA TATCACACTTTTAATTACTGTAACTTTATAATAAGATTTTATATCTGTAGTAGAAGTCCAACTTTGTAATCCCTCCCAATTGGCTTGGCT ATTCTTGGCCTTTTGCATTTCCATATAATTTTTTATTTTTGTTTTGAAACGAAGTTTCGCTCTTGTTGCCCAGGCTGGAGTGCAGTGGCG CGATCTCGGCTCACTGCAACCTCCGCCTCCCAGGTTCAAGTGATCCTCCTGCCTCAGACTCCCGAGTAGCTGGGATTACAGGTGCCCACC ACCATGCCCAGCTAATTTTTGTATTTTTAGTAGAGACAGGGTTTCACCATGTTGGCCAGCCTGGTCTTGAACTCCTGACCTCAGGTGATC CACACCCACCTTGGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACCGCGCCTGGTTGCATTCCCATATAAATTTAAAAACAATCTA CTGAAAGATGTATACGACCTCCACCAAGAAAATTGTAAGACATTTGGAGAAGTTTAAAAAGACATGAATAAACGGAAATGGTTTTTTTAA ATAAACAAATGATTTTTAAAGTTGATCATTAGGTTAATAAATAGTCATATAATGACAATCCGATGAGATTATGTTGCCCAGGGTGGTCTC TAACTCCTAGCCTCAAGCAGTTTTACTCTCTCATTACAGGTGTAGGCCACCGTGCCTGGCCTGACACTTGGAAATCTTAATCACAATTAT TCTTTGTTTTTATAATGTTTACTGTTCAAATCAATTTCTGGTTGGATAGTATGTATATATAAAGCCATGCTCAATGGCCTAGATATATTT ACTGCCAAATCTTTTATGCTTTTAGTGTTTTTTTTCTGGACAAGATCTATGCTTATTGCAATAAATTAAATGCAAAGAATATTCTAGTAG AAAGTCAGTCTGCACTTCCTAAACCCCACCCCACCCCACCAATTCCTTCATAACTGTTATTAACAGTTAGCTGTGTTTTCTAATGGATTA TCTCCAAAGTATATGTAACTCAGATTTTTGTGAGGTAGGAAAAGAATAACATTAATTCCACTTCACATATTGAAAGTCTAACATACAAAG AGATTAAATATCTCCTTTCTTTTGCCAAATGTTAATGAATTGTCTTATGAGAATTAAGATATGATACTTTCTCCCAAGCTATACTGTTTC CCATAAAGTATTTGAGATGTTGGAGATTCAAGGGAAAAAATATAAATGCTTAGAAATAAAGTGTATAATGCAAAGATTGTGAATAAAGTG |
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FusionGenePPI for GNE_ROCK1 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| GNE | ELAVL1, GABPA, RBM12, KCTD12, RAB3GAP1, RAB3GAP2, SMARCAD1, TSEN34, KRTAP5-9, KRT31, GNE, SPRY2, ADAMTSL4, KRTAP4-12, KRTAP9-2, GTPBP3, KRTAP10-7, KRTAP10-9, KRTAP10-5, KRTAP10-8, KRTAP10-3, NOTCH2NL, C2orf68, NTRK1, LGALS3BP, ZNF764, TIMM50 | ROCK1 | CDC25A, PFN2, RHOA, RND3, GAB1, CFL1, LIMK2, HNRNPA1, ITSN2, ARRB1, TSG101, NOTCH1, SMURF1, SMAD2, CASP3, CASP7, CDK15, ANKFY1, MON2, FAM21A, KIAA1033, IKBKB, LMO2, MAGEB4, POLR3C, C6orf165, FAM124A, NXF1, NTRK1, MED23, XRCC5, NEIL3, TRIM15, HGS, SLC9A1, UBE2T, CDKN3, TENC1, ROCK2, ADD2, IL20RA, CYLD |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for GNE_ROCK1 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for GNE_ROCK1 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | GNE | C1853926 | NONAKA MYOPATHY | 12 | CTD_human;ORPHANET;UNIPROT |
| Hgene | GNE | C0342853 | Sialuria | 3 | CTD_human;UNIPROT |
| Hgene | GNE | C0238190 | Inclusion Body Myositis (disorder) | 1 | CTD_human |
| Hgene | GNE | C1833373 | Inclusion Body Myopathy, Autosomal Recessive | 1 | CTD_human |
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