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Center for Computational Systems Medicine
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FusionGeneSummary

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FusionProtFeature

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FusionGeneSequence

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FusionGenePPI

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RelatedDrugs

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RelatedDiseases

Fusion gene ID: 14943

FusionGeneSummary for GNE_ROCK1

check button Fusion gene summary
Fusion gene informationFusion gene name: GNE_ROCK1
Fusion gene ID: 14943
HgeneTgene
Gene symbol

GNE

ROCK1

Gene ID

10020

6093

Gene nameglucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinaseRho associated coiled-coil containing protein kinase 1
SynonymsDMRV|GLCNE|IBM2|NM|Uae1P160ROCK|ROCK-I
Cytomap

9p13.3

18q11.1

Type of geneprotein-codingprotein-coding
Descriptionbifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinaseN-acylmannosamine kinaseUDP-GlcNAc-2-epimerase/ManAc kinaseUDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinaserho-associated protein kinase 1p160 ROCK-1renal carcinoma antigen NY-REN-35
Modification date2018051920180527
UniProtAcc

Q9Y223

Q13464

Ensembl transtripts involved in fusion geneENST00000396594, ENST00000539815, 
ENST00000543356, ENST00000539208, 
ENST00000447283, ENST00000377902, 
ENST00000399799, 
Fusion gene scores* DoF score6 X 6 X 4=1442 X 2 X 2=8
# samples 62
** MAII scorelog2(6/144*10)=-1.26303440583379
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
log2(2/8*10)=1.32192809488736
Context

PubMed: GNE [Title/Abstract] AND ROCK1 [Title/Abstract] AND fusion [Title/Abstract]

Functional or gene categories assigned by FusionGDB annotation
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneROCK1

GO:0007159

leukocyte cell-cell adhesion

12082081

TgeneROCK1

GO:0022614

membrane to membrane docking

12082081

TgeneROCK1

GO:0032091

negative regulation of protein binding

18573880

TgeneROCK1

GO:0032956

regulation of actin cytoskeleton organization

25911094

TgeneROCK1

GO:0050900

leukocyte migration

12082081

TgeneROCK1

GO:0050901

leukocyte tethering or rolling

12082081


check button Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
Data typeSourceCancer typeSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
TCGARVLUSCTCGA-56-A49D-01AGNEchr9

36236829

-ROCK1chr18

18650574

-
* LD: Li Ding group's fusion gene list
  RV: Roel Verhaak group's fusion gene list
  ChiTaRs fusion database

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
Frame-shitENST00000396594ENST00000399799GNEchr9

36236829

-ROCK1chr18

18650574

-
Frame-shitENST00000539815ENST00000399799GNEchr9

36236829

-ROCK1chr18

18650574

-
Frame-shitENST00000543356ENST00000399799GNEchr9

36236829

-ROCK1chr18

18650574

-
intron-3CDSENST00000539208ENST00000399799GNEchr9

36236829

-ROCK1chr18

18650574

-
In-frameENST00000447283ENST00000399799GNEchr9

36236829

-ROCK1chr18

18650574

-
In-frameENST00000377902ENST00000399799GNEchr9

36236829

-ROCK1chr18

18650574

-

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FusionProtFeatures for GNE_ROCK1


check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
GNE

Q9Y223

ROCK1

Q13464

Protein kinase which is a key regulator of actincytoskeleton and cell polarity. Involved in regulation of smoothmuscle contraction, actin cytoskeleton organization, stress fiberand focal adhesion formation, neurite retraction, cell adhesionand motility via phosphorylation of DAPK3, GFAP, LIMK1, LIMK2,MYL9/MLC2, PFN1 and PPP1R12A. Phosphorylates FHOD1 and actssynergistically with it to promote SRC-dependent non-apoptoticplasma membrane blebbing. Phosphorylates JIP3 and regulates therecruitment of JNK to JIP3 upon UVB-induced stress. Acts as asuppressor of inflammatory cell migration by regulating PTENphosphorylation and stability. Acts as a negative regulator ofVEGF-induced angiogenic endothelial cell activation. Required forcentrosome positioning and centrosome-dependent exit from mitosis.Plays a role in terminal erythroid differentiation. May regulateclosure of the eyelids and ventral body wall by inducing theassembly of actomyosin bundles. Promotes keratinocyte terminaldifferentiation. Involved in osteoblast compaction through thefibronectin fibrillogenesis cell-mediated matrix assembly process,essential for osteoblast mineralization.{ECO:0000269|PubMed:10436159, ECO:0000269|PubMed:10652353,ECO:0000269|PubMed:11018042, ECO:0000269|PubMed:11283607,ECO:0000269|PubMed:17158456, ECO:0000269|PubMed:18573880,ECO:0000269|PubMed:18694941, ECO:0000269|PubMed:19036714,ECO:0000269|PubMed:19131646, ECO:0000269|PubMed:19181962,ECO:0000269|PubMed:19997641, ECO:0000269|PubMed:21072057,ECO:0000269|PubMed:8617235, ECO:0000269|PubMed:9722579}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

.

* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note


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FusionGeneSequence for GNE_ROCK1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.
>In-frame_GNE_ENST00000447283_chr9_36236829_-_ROCK1_ENST00000399799_chr18_18650574_-_1580aa
MEKNGNNRKLRVCVATCNRADTSKLAPIMFGIKTEPEFFELDVVVLGSHLIDDTGNTTRMIEQDDFDINTRLHTIVRGEDEAAMVESVGL
ALVKLPDVLNRLKPDIMIVHGDRFDALALATSAALMNIRILHIEGGEVSGTIDDSIRHAITKLAHTHVCCTRSAEQHLISMCEDHDRILL
AGCPSTDKLLSAKNKDYMSIIRMWLGDDVKSKDYIVALQHPVTTDIKHSIKMFELTLDALISFNKRTLVLFPNIDAGWIGCFGI_FGFSC
LKKKQKT_QLFKQI_RHNK_NQRFTNES_RL_SSEGDW_RCIWRSSIGKA_IHQEGICTEASQQI_NDKEI_FCFFLGRKGHHGFCQQSL
GCSAFLCIPR_SLSLHGDGIHAWWRSCKLNEQL_CA_KMGTILYCRSSSCIGCNPFHGFTSQRCEA__HAAG_IWTFEVSRFWYLTEDE_
GRHGTM_YSGWNT_LTFP_SIKIPRW_WLLWKRM_LVVGWGIFIRNACR_YTFLCRFFGWNLQ_NTEP_KFTYLS____HIKRSKKPTLC
LPY_QGSEVRAKWCRRNQTTSLLQK_PVGLGNAPRHCSTSCTRFK__H_Y__F__LGRR_RRGRNIPTS_SFRWQSTTFCRIYIL_QS_I
LIFSKS___QN_LQCR_KLAGKFAKNNL_AGRTAA__NAVKR_NGAEVQNLKHKTRQDNERIG_RGKSKKKSRIYSVSD_EGENVATA_N
__VPKKS_TGK_EEKKCRK_SFYIKGSVGRLKESQSEFTAC__EAVPVTKAARRSQ_LT_DRIGHSCKIEEESHRDEQVN_SVRVPEQRV
AREKSNFREF_VTNRQRLLPAASTIRS_TKRQRS_F_DDWRPSSSNYIFTRGGEASQT_SRKSGRRKKRGSRHA_SLRKGKE_FRDRFKL
QT_IITTTVRTRGK_TQSNQSSFN_QTSIT_RGKVCGNV_DGKKAERRKRSSREG_KSGCSD_ETVFHARR_SEAISAETRTFDWK_RKD
GG_S_ESNPATGAGIK_AAVVTK_IEDSSI_GRQFKRFRKADETGNKYFIGSKEIIRI_VSSAYETV_RK_RTDAGATRSA_S_AIFLDT
L_NPGKGT_RRN_RKKQRKFKENTGTTK_KRNSCYSVGSSRNKS_V_AVGARPSGRTVF_IDARKQESCFKK_TRDYR_RSHC_SA_RSK
QHANQRT_NIKKRE_RANRENEEGRGRI_TGEGGGDQ_S_GCL_KETQH_TNP_NTGC_QIGRNNESKRF_N__KES_YTRFEKERKGKS
KAATGTQPRKREIQPDGSETSEGTE_HASAIGRRMCT_E_ASDAVGQQRE_T_AIAC_TFGPLGFYKCC_FS_C__N_W_PPRVKN_RLA
FSTK_RKTQTIWLEETVCCGKQQKNFVL__RTR_GAIQSITGIGHR_TVSR_TCNPRRCV_S_N_RNS_NIPDTICK_R_M_KRCRDGTS
TTS_KN_FPKSQRP_VTSYTLPLSCQL_CLCQTSLACF_ATPCPRVSKMPC_VPQRSLR_ERGLNLSM_SKL_CNISKRTAAVSMFSG_T

>In-frame_GNE_ENST00000377902_chr9_36236829_-_ROCK1_ENST00000399799_chr18_18650574_-_1580aa
MEKNGNNRKLRVCVATCNRADTSKLAPIMFGIKTEPEFFELDVVVLGSHLIDDTGNTTRMIEQDDFDINTRLHTIVRGEDEAAMVESVGL
ALVKLPDVLNRLKPDIMIVHGDRFDALALATSAALMNIRILHIEGGEVSGTIDDSIRHAITKLAHTHVCCTRSAEQHLISMCEDHDRILL
AGCPSTDKLLSAKNKDYMSIIRMWLGDDVKSKDYIVALQHPVTTDIKHSIKMFELTLDALISFNKRTLVLFPNIDAGWIGCFGI_FGFSC
LKKKQKT_QLFKQI_RHNK_NQRFTNES_RL_SSEGDW_RCIWRSSIGKA_IHQEGICTEASQQI_NDKEI_FCFFLGRKGHHGFCQQSL
GCSAFLCIPR_SLSLHGDGIHAWWRSCKLNEQL_CA_KMGTILYCRSSSCIGCNPFHGFTSQRCEA__HAAG_IWTFEVSRFWYLTEDE_
GRHGTM_YSGWNT_LTFP_SIKIPRW_WLLWKRM_LVVGWGIFIRNACR_YTFLCRFFGWNLQ_NTEP_KFTYLS____HIKRSKKPTLC
LPY_QGSEVRAKWCRRNQTTSLLQK_PVGLGNAPRHCSTSCTRFK__H_Y__F__LGRR_RRGRNIPTS_SFRWQSTTFCRIYIL_QS_I
LIFSKS___QN_LQCR_KLAGKFAKNNL_AGRTAA__NAVKR_NGAEVQNLKHKTRQDNERIG_RGKSKKKSRIYSVSD_EGENVATA_N
__VPKKS_TGK_EEKKCRK_SFYIKGSVGRLKESQSEFTAC__EAVPVTKAARRSQ_LT_DRIGHSCKIEEESHRDEQVN_SVRVPEQRV
AREKSNFREF_VTNRQRLLPAASTIRS_TKRQRS_F_DDWRPSSSNYIFTRGGEASQT_SRKSGRRKKRGSRHA_SLRKGKE_FRDRFKL
QT_IITTTVRTRGK_TQSNQSSFN_QTSIT_RGKVCGNV_DGKKAERRKRSSREG_KSGCSD_ETVFHARR_SEAISAETRTFDWK_RKD
GG_S_ESNPATGAGIK_AAVVTK_IEDSSI_GRQFKRFRKADETGNKYFIGSKEIIRI_VSSAYETV_RK_RTDAGATRSA_S_AIFLDT
L_NPGKGT_RRN_RKKQRKFKENTGTTK_KRNSCYSVGSSRNKS_V_AVGARPSGRTVF_IDARKQESCFKK_TRDYR_RSHC_SA_RSK
QHANQRT_NIKKRE_RANRENEEGRGRI_TGEGGGDQ_S_GCL_KETQH_TNP_NTGC_QIGRNNESKRF_N__KES_YTRFEKERKGKS
KAATGTQPRKREIQPDGSETSEGTE_HASAIGRRMCT_E_ASDAVGQQRE_T_AIAC_TFGPLGFYKCC_FS_C__N_W_PPRVKN_RLA
FSTK_RKTQTIWLEETVCCGKQQKNFVL__RTR_GAIQSITGIGHR_TVSR_TCNPRRCV_S_N_RNS_NIPDTICK_R_M_KRCRDGTS
TTS_KN_FPKSQRP_VTSYTLPLSCQL_CLCQTSLACF_ATPCPRVSKMPC_VPQRSLR_ERGLNLSM_SKL_CNISKRTAAVSMFSG_T


* Fusion transcript sequences (only coding sequence (CDS) region).
>In-frame_GNE_ENST00000447283_chr9_36236829_-_ROCK1_ENST00000399799_chr18_18650574_-_4741nt
ATGGAGAAGAATGGAAATAACCGAAAGCTGCGGGTTTGTGTTGCTACTTGTAACCGTGCAGATTATTCTAAACTTGCCCCGATCATGTTT
GGCATTAAAACCGAACCTGAGTTCTTTGAACTTGATGTTGTGGTACTTGGCTCTCACCTGATAGATGACTATGGAAATACATATCGAATG
ATTGAACAAGATGACTTTGACATTAACACCAGGCTACACACAATTGTGAGGGGAGAAGATGAGGCAGCCATGGTGGAGTCAGTAGGCCTG
GCCCTAGTGAAGCTGCCAGATGTCCTTAATCGCCTGAAGCCTGATATCATGATTGTTCATGGAGACAGGTTTGATGCCCTGGCTCTGGCC
ACATCTGCTGCCTTGATGAACATCCGAATCCTTCACATTGAAGGTGGGGAAGTCAGTGGGACCATTGATGACTCTATCAGACATGCCATA
ACAAAACTGGCTCATTATCATGTGTGCTGCACCCGCAGTGCAGAGCAGCACCTGATATCCATGTGTGAGGACCATGATCGCATCCTTTTG
GCAGGCTGCCCTTCCTATGACAAACTTCTCTCAGCCAAGAACAAAGACTACATGAGCATCATTCGCATGTGGCTAGGTGATGATGTAAAA
TCTAAAGATTACATTGTTGCACTACAGCACCCTGTGACCACTGACATTAAGCATTCCATAAAAATGTTTGAATTAACATTGGATGCACTT
ATCTCATTTAACAAGCGGACCCTAGTCCTGTTTCCAAATATTGACGCAGGATGGATTGGATGCTTTGGTATATGATTTGGATTTTCCTGC
CTTAAGAAAAAACAAAAATATTGACAACTTTTTAAGCAGATATAAAGACACAATAAATAAAATCAGAGATTTACGAATGAAAGCTGAAGA
TTATGAAGTAGTGAAGGTGATTGGTAGAGGTGCATTTGGAGAAGTTCAATTGGTAAGGCATAAATCCACCAGGAAGGTATATGCTATGAA
GCTTCTCAGCAAATTTGAAATGATAAAGAGATCTGATTCTGCTTTTTTCTGGGAAGAAAGGGACATCATGGCTTTTGCCAACAGTCCTTG
GGTTGTTCAGCTTTTTTATGCATTCCAAGATGATCGTTATCTCTACATGGTGATGGAATACATGCCTGGTGGAGATCTTGTAAACTTAAT
GAGCAACTATGATGTGCCTGAAAAATGGGCACGATTCTATACTGCAGAAGTAGTTCTTGCATTGGATGCAATCCATTCCATGGGTTTTAT
TCACAGAGATGTGAAGCCTGATAACATGCTGCTGGATAAATCTGGACATTTGAAGTTAGCAGATTTTGGTACTTGTATGAAGATGAATAA
GGAAGGCATGGTACGATGTGATACAGCGGTTGGAACACCTGATTATATTTCCCCTGAAGTATTAAAATCCCAAGGTGGTGATGGTTATTA
TGGAAGAGAATGTGACTGGTGGTCGGTTGGGGTATTTTTATACGAAATGCTTGTAGGTGATACACCTTTTTATGCAGATTCTTTGGTTGG
AACTTACAGTAAAATTATGAACCATAAAAATTCACTTACCTTTCCTGATGATAATGACATATCAAAAGAAGCAAAAAACCTTATTTGTGC
CTTCCTTACTGACAGGGAAGTGAGGTTAGGGCGAAATGGTGTAGAAGAAATCAAACGACATCTCTTCTTCAAAAATGACCAGTGGGCTTG
GGAAACGCTCCGAGACACTGTAGCACCAGTTGTACCCGATTTAAGTAGTGACATTGATACTAGTAATTTTGATGACTTGGAAGAAGATAA
AGGAGAGGAAGAAACATTCCCTATTCCTAAAGCTTTCGTTGGCAATCAACTACCTTTTGTAGGATTTACATATTATAGCAATCGTAGATA
CTTATCTTCAGCAAATCCTAATGATAACAGAACTAGCTCCAATGCAGATAAAAGCTTGCAGGAAAGTTTGCAAAAAACAATCTATAAGCT
GGAAGAACAGCTGCATAATGAAATGCAGTTAAAAGATGAAATGGAGCAGAAGTGCAGAACCTCAAACATAAAACTAGACAAGATAATGAA
AGAATTGGATGAAGAGGGAAATCAAAGAAGAAATCTAGAATCTACAGTGTCTCAGATTGAGAAGGAGAAAATGTTGCTACAGCATAGAAT
TAATGAGTACCAAAGAAAAGCTGAACAGGAAAATGAGAAGAGAAGAAATGTAGAAAATGAAGTTTCTACATTAAAGGATCAGTTGGAAGA
CTTAAAGAAAGTCAGTCAGAATTCACAGCTTGCTAATGAGAAGCTGTCCCAGTTACAAAAGCAGCTAGAAGAAGCCAATGACTTACTTAG
GACAGAATCGGACACAGCTGTAAGATTGAGGAAGAGTCACACAGAGATGAGCAAGTCAATTAGTCAGTTAGAGTCCCTGAACAGAGAGTT
GCAAGAGAGAAATCGAATTTTAGAGAATTCTAAGTCACAAACAGACAAAGATTATTACCAGCTGCAAGCTATATTAGAAGCTGAACGAAG
AGACAGAGGTCATGATTCTGAGATGATTGGAGACCTTCAAGCTCGAATTACATCTTTACAAGAGGAGGTGAAGCATCTCAAACATAATCT
CGAAAAAGTGGAAGGAGAAAGAAAAGAGGCTCAAGACATGCTTAATCACTCAGAAAAGGAAAAGAATAATTTAGAGATAGATTTAAACTA
CAAACTTAAATCATTACAACAACGGTTAGAACAAGAGGTAAATGAACACAAAGTAACCAAAGCTCGTTTAACTGACAAACATCAATCTAT
TGAAGAGGCAAAGTCTGTGGCAATGTGTGAGATGGAAAAAAAGCTGAAAGAAGAAAGAGAAGCTCGAGAGAAGGCTGAAAATCGGGTTGT
TCAGATTGAGAAACAGTGTTCCATGCTAGACGTTGATCTGAAGCAATCTCAGCAGAAACTAGAACATTTGACTGGAAATAAAGAAAGGAT
GGAGGATGAAGTTAAGAATCTAACCCTGCAACTGGAGCAGGAATCAAATAAGCGGCTGTTGTTACAAAATGAATTGAAGACTCAAGCATT
TGAGGCAGACAATTTAAAAGGTTTAGAAAAGCAGATGAAACAGGAAATAAATACTTTATTGGAAGCAAAGAGATTATTAGAATTTGAGTT
AGCTCAGCTTACGAAACAGTATAGAGGAAATGAAGGACAGATGCGGGAGCTACAAGATCAGCTTGAAGCTGAGCAATATTTCTCGACACT
TTATAAAACCCAGGTAAAGGAACTTAAAGAAGAAATTGAAGAAAAAAACAGAGAAAATTTAAAGAAAATACAGGAACTACAAAATGAAAA
AGAAACTCTTGCTACTCAGTTGGATCTAGCAGAAACAAAAGCTGAGTCTGAGCAGTTGGCGCGAGGCCTTCTGGAAGAACAGTATTTTGA
ATTGACGCAAGAAAGCAAGAAAGCTGCTTCAAGAAATAGACAAGAGATTACAGATAAAGATCACACTGTTAGTCGGCTTGAAGAAGCAAA
CAGCATGCTAACCAAAGATATTGAAATATTAAGAAGAGAGAATGAAGAGCTAACAGAGAAAATGAAGAAGGCAGAGGAAGAATATAAACT
GGAGAAGGAGGAGGAGATCAGTAATCTTAAGGCTGCCTTTGAAAAGAATATCAACACTGAACGAACCCTTAAAACACAGGCTGTTAACAA
ATTGGCAGAAATAATGAATCGAAAAGATTTTAAAATTGATAGAAAGAAAGCTAATACACAAGATTTGAGAAAGAAAGAAAAGGAAAATCG
AAAGCTGCAACTGGAACTCAACCAAGAAAGAGAGAAATTCAACCAGATGGTAGTGAAACATCAGAAGGAACTGAATGACATGCAAGCGCA
ATTGGTAGAAGAATGTGCACATAGGAATGAGCTTCAGATGCAGTTGGCCAGCAAAGAGAGTGATATTGAGCAATTGCGTGCTAAACTTTT
GGACCTCTCGGATTCTACAAGTGTTGCTAGTTTTCCTAGTGCTGATGAAACTGATGGTAACCTCCCAGAGTCAAGAATTGAAGGTTGGCT
TTCAGTACCAAATAGAGGAAATATCAAACGATATGGCTGGAAGAAACAGTATGTTGTGGTAAGCAGCAAAAAAATTTTGTTCTATAATGA
CGAACAAGATAAGGAGCAATCCAATCCATCTATGGTATTGGACATAGATAAACTGTTTCACGTTAGACCTGTAACCCAAGGAGATGTGTA
TAGAGCTGAAACTGAAGAAATTCCTAAAATATTCCAGATACTATATGCAAATGAAGGTGAATGTAGAAAAGATGTAGAGATGGAACCAGT
ACAACAAGCTGAAAAAACTAATTTCCAAAATCACAAAGGCCATGAGTTTATTCCTACACTCTACCACTTTCCTGCCAATTGTGATGCCTG
TGCCAAACCTCTCTGGCATGTTTTTAAGCCACCCCCTGCCCTAGAGTGTCGAAGATGCCATGTTAAGTGCCACAGAGATCACTTAGATAA
GAAAGAGGACTTAATTTGTCCATGTAAAGTAAGTTATGATGTAACATCAGCAAGAGATATGCTGCTGTTAGCATGTTCTCAGGATGAACA
AAAAAAATGGGTAACTCATTTAGTAAAGAAAATCCCTAAGAATCCACCATCTGGTTTTGTTCGTGCTTCCCCTCGAACGCTTTCTACAAG

>In-frame_GNE_ENST00000377902_chr9_36236829_-_ROCK1_ENST00000399799_chr18_18650574_-_4741nt
ATGGAGAAGAATGGAAATAACCGAAAGCTGCGGGTTTGTGTTGCTACTTGTAACCGTGCAGATTATTCTAAACTTGCCCCGATCATGTTT
GGCATTAAAACCGAACCTGAGTTCTTTGAACTTGATGTTGTGGTACTTGGCTCTCACCTGATAGATGACTATGGAAATACATATCGAATG
ATTGAACAAGATGACTTTGACATTAACACCAGGCTACACACAATTGTGAGGGGAGAAGATGAGGCAGCCATGGTGGAGTCAGTAGGCCTG
GCCCTAGTGAAGCTGCCAGATGTCCTTAATCGCCTGAAGCCTGATATCATGATTGTTCATGGAGACAGGTTTGATGCCCTGGCTCTGGCC
ACATCTGCTGCCTTGATGAACATCCGAATCCTTCACATTGAAGGTGGGGAAGTCAGTGGGACCATTGATGACTCTATCAGACATGCCATA
ACAAAACTGGCTCATTATCATGTGTGCTGCACCCGCAGTGCAGAGCAGCACCTGATATCCATGTGTGAGGACCATGATCGCATCCTTTTG
GCAGGCTGCCCTTCCTATGACAAACTTCTCTCAGCCAAGAACAAAGACTACATGAGCATCATTCGCATGTGGCTAGGTGATGATGTAAAA
TCTAAAGATTACATTGTTGCACTACAGCACCCTGTGACCACTGACATTAAGCATTCCATAAAAATGTTTGAATTAACATTGGATGCACTT
ATCTCATTTAACAAGCGGACCCTAGTCCTGTTTCCAAATATTGACGCAGGATGGATTGGATGCTTTGGTATATGATTTGGATTTTCCTGC
CTTAAGAAAAAACAAAAATATTGACAACTTTTTAAGCAGATATAAAGACACAATAAATAAAATCAGAGATTTACGAATGAAAGCTGAAGA
TTATGAAGTAGTGAAGGTGATTGGTAGAGGTGCATTTGGAGAAGTTCAATTGGTAAGGCATAAATCCACCAGGAAGGTATATGCTATGAA
GCTTCTCAGCAAATTTGAAATGATAAAGAGATCTGATTCTGCTTTTTTCTGGGAAGAAAGGGACATCATGGCTTTTGCCAACAGTCCTTG
GGTTGTTCAGCTTTTTTATGCATTCCAAGATGATCGTTATCTCTACATGGTGATGGAATACATGCCTGGTGGAGATCTTGTAAACTTAAT
GAGCAACTATGATGTGCCTGAAAAATGGGCACGATTCTATACTGCAGAAGTAGTTCTTGCATTGGATGCAATCCATTCCATGGGTTTTAT
TCACAGAGATGTGAAGCCTGATAACATGCTGCTGGATAAATCTGGACATTTGAAGTTAGCAGATTTTGGTACTTGTATGAAGATGAATAA
GGAAGGCATGGTACGATGTGATACAGCGGTTGGAACACCTGATTATATTTCCCCTGAAGTATTAAAATCCCAAGGTGGTGATGGTTATTA
TGGAAGAGAATGTGACTGGTGGTCGGTTGGGGTATTTTTATACGAAATGCTTGTAGGTGATACACCTTTTTATGCAGATTCTTTGGTTGG
AACTTACAGTAAAATTATGAACCATAAAAATTCACTTACCTTTCCTGATGATAATGACATATCAAAAGAAGCAAAAAACCTTATTTGTGC
CTTCCTTACTGACAGGGAAGTGAGGTTAGGGCGAAATGGTGTAGAAGAAATCAAACGACATCTCTTCTTCAAAAATGACCAGTGGGCTTG
GGAAACGCTCCGAGACACTGTAGCACCAGTTGTACCCGATTTAAGTAGTGACATTGATACTAGTAATTTTGATGACTTGGAAGAAGATAA
AGGAGAGGAAGAAACATTCCCTATTCCTAAAGCTTTCGTTGGCAATCAACTACCTTTTGTAGGATTTACATATTATAGCAATCGTAGATA
CTTATCTTCAGCAAATCCTAATGATAACAGAACTAGCTCCAATGCAGATAAAAGCTTGCAGGAAAGTTTGCAAAAAACAATCTATAAGCT
GGAAGAACAGCTGCATAATGAAATGCAGTTAAAAGATGAAATGGAGCAGAAGTGCAGAACCTCAAACATAAAACTAGACAAGATAATGAA
AGAATTGGATGAAGAGGGAAATCAAAGAAGAAATCTAGAATCTACAGTGTCTCAGATTGAGAAGGAGAAAATGTTGCTACAGCATAGAAT
TAATGAGTACCAAAGAAAAGCTGAACAGGAAAATGAGAAGAGAAGAAATGTAGAAAATGAAGTTTCTACATTAAAGGATCAGTTGGAAGA
CTTAAAGAAAGTCAGTCAGAATTCACAGCTTGCTAATGAGAAGCTGTCCCAGTTACAAAAGCAGCTAGAAGAAGCCAATGACTTACTTAG
GACAGAATCGGACACAGCTGTAAGATTGAGGAAGAGTCACACAGAGATGAGCAAGTCAATTAGTCAGTTAGAGTCCCTGAACAGAGAGTT
GCAAGAGAGAAATCGAATTTTAGAGAATTCTAAGTCACAAACAGACAAAGATTATTACCAGCTGCAAGCTATATTAGAAGCTGAACGAAG
AGACAGAGGTCATGATTCTGAGATGATTGGAGACCTTCAAGCTCGAATTACATCTTTACAAGAGGAGGTGAAGCATCTCAAACATAATCT
CGAAAAAGTGGAAGGAGAAAGAAAAGAGGCTCAAGACATGCTTAATCACTCAGAAAAGGAAAAGAATAATTTAGAGATAGATTTAAACTA
CAAACTTAAATCATTACAACAACGGTTAGAACAAGAGGTAAATGAACACAAAGTAACCAAAGCTCGTTTAACTGACAAACATCAATCTAT
TGAAGAGGCAAAGTCTGTGGCAATGTGTGAGATGGAAAAAAAGCTGAAAGAAGAAAGAGAAGCTCGAGAGAAGGCTGAAAATCGGGTTGT
TCAGATTGAGAAACAGTGTTCCATGCTAGACGTTGATCTGAAGCAATCTCAGCAGAAACTAGAACATTTGACTGGAAATAAAGAAAGGAT
GGAGGATGAAGTTAAGAATCTAACCCTGCAACTGGAGCAGGAATCAAATAAGCGGCTGTTGTTACAAAATGAATTGAAGACTCAAGCATT
TGAGGCAGACAATTTAAAAGGTTTAGAAAAGCAGATGAAACAGGAAATAAATACTTTATTGGAAGCAAAGAGATTATTAGAATTTGAGTT
AGCTCAGCTTACGAAACAGTATAGAGGAAATGAAGGACAGATGCGGGAGCTACAAGATCAGCTTGAAGCTGAGCAATATTTCTCGACACT
TTATAAAACCCAGGTAAAGGAACTTAAAGAAGAAATTGAAGAAAAAAACAGAGAAAATTTAAAGAAAATACAGGAACTACAAAATGAAAA
AGAAACTCTTGCTACTCAGTTGGATCTAGCAGAAACAAAAGCTGAGTCTGAGCAGTTGGCGCGAGGCCTTCTGGAAGAACAGTATTTTGA
ATTGACGCAAGAAAGCAAGAAAGCTGCTTCAAGAAATAGACAAGAGATTACAGATAAAGATCACACTGTTAGTCGGCTTGAAGAAGCAAA
CAGCATGCTAACCAAAGATATTGAAATATTAAGAAGAGAGAATGAAGAGCTAACAGAGAAAATGAAGAAGGCAGAGGAAGAATATAAACT
GGAGAAGGAGGAGGAGATCAGTAATCTTAAGGCTGCCTTTGAAAAGAATATCAACACTGAACGAACCCTTAAAACACAGGCTGTTAACAA
ATTGGCAGAAATAATGAATCGAAAAGATTTTAAAATTGATAGAAAGAAAGCTAATACACAAGATTTGAGAAAGAAAGAAAAGGAAAATCG
AAAGCTGCAACTGGAACTCAACCAAGAAAGAGAGAAATTCAACCAGATGGTAGTGAAACATCAGAAGGAACTGAATGACATGCAAGCGCA
ATTGGTAGAAGAATGTGCACATAGGAATGAGCTTCAGATGCAGTTGGCCAGCAAAGAGAGTGATATTGAGCAATTGCGTGCTAAACTTTT
GGACCTCTCGGATTCTACAAGTGTTGCTAGTTTTCCTAGTGCTGATGAAACTGATGGTAACCTCCCAGAGTCAAGAATTGAAGGTTGGCT
TTCAGTACCAAATAGAGGAAATATCAAACGATATGGCTGGAAGAAACAGTATGTTGTGGTAAGCAGCAAAAAAATTTTGTTCTATAATGA
CGAACAAGATAAGGAGCAATCCAATCCATCTATGGTATTGGACATAGATAAACTGTTTCACGTTAGACCTGTAACCCAAGGAGATGTGTA
TAGAGCTGAAACTGAAGAAATTCCTAAAATATTCCAGATACTATATGCAAATGAAGGTGAATGTAGAAAAGATGTAGAGATGGAACCAGT
ACAACAAGCTGAAAAAACTAATTTCCAAAATCACAAAGGCCATGAGTTTATTCCTACACTCTACCACTTTCCTGCCAATTGTGATGCCTG
TGCCAAACCTCTCTGGCATGTTTTTAAGCCACCCCCTGCCCTAGAGTGTCGAAGATGCCATGTTAAGTGCCACAGAGATCACTTAGATAA
GAAAGAGGACTTAATTTGTCCATGTAAAGTAAGTTATGATGTAACATCAGCAAGAGATATGCTGCTGTTAGCATGTTCTCAGGATGAACA
AAAAAAATGGGTAACTCATTTAGTAAAGAAAATCCCTAAGAATCCACCATCTGGTTTTGTTCGTGCTTCCCCTCGAACGCTTTCTACAAG


* Fusion transcript sequences (Full-length transcript).
>In-frame_GNE_ENST00000447283_chr9_36236829_-_ROCK1_ENST00000399799_chr18_18650574_-_9270nt
CGGCGTCTGGAACTCTATTTTAAGAACCTCTCAAAACGAAACAAGCAAATCATGGAGAAGAATGGAAATAACCGAAAGCTGCGGGTTTGT
GTTGCTACTTGTAACCGTGCAGATTATTCTAAACTTGCCCCGATCATGTTTGGCATTAAAACCGAACCTGAGTTCTTTGAACTTGATGTT
GTGGTACTTGGCTCTCACCTGATAGATGACTATGGAAATACATATCGAATGATTGAACAAGATGACTTTGACATTAACACCAGGCTACAC
ACAATTGTGAGGGGAGAAGATGAGGCAGCCATGGTGGAGTCAGTAGGCCTGGCCCTAGTGAAGCTGCCAGATGTCCTTAATCGCCTGAAG
CCTGATATCATGATTGTTCATGGAGACAGGTTTGATGCCCTGGCTCTGGCCACATCTGCTGCCTTGATGAACATCCGAATCCTTCACATT
GAAGGTGGGGAAGTCAGTGGGACCATTGATGACTCTATCAGACATGCCATAACAAAACTGGCTCATTATCATGTGTGCTGCACCCGCAGT
GCAGAGCAGCACCTGATATCCATGTGTGAGGACCATGATCGCATCCTTTTGGCAGGCTGCCCTTCCTATGACAAACTTCTCTCAGCCAAG
AACAAAGACTACATGAGCATCATTCGCATGTGGCTAGGTGATGATGTAAAATCTAAAGATTACATTGTTGCACTACAGCACCCTGTGACC
ACTGACATTAAGCATTCCATAAAAATGTTTGAATTAACATTGGATGCACTTATCTCATTTAACAAGCGGACCCTAGTCCTGTTTCCAAAT
ATTGACGCAGGATGGATTGGATGCTTTGGTATATGATTTGGATTTTCCTGCCTTAAGAAAAAACAAAAATATTGACAACTTTTTAAGCAG
ATATAAAGACACAATAAATAAAATCAGAGATTTACGAATGAAAGCTGAAGATTATGAAGTAGTGAAGGTGATTGGTAGAGGTGCATTTGG
AGAAGTTCAATTGGTAAGGCATAAATCCACCAGGAAGGTATATGCTATGAAGCTTCTCAGCAAATTTGAAATGATAAAGAGATCTGATTC
TGCTTTTTTCTGGGAAGAAAGGGACATCATGGCTTTTGCCAACAGTCCTTGGGTTGTTCAGCTTTTTTATGCATTCCAAGATGATCGTTA
TCTCTACATGGTGATGGAATACATGCCTGGTGGAGATCTTGTAAACTTAATGAGCAACTATGATGTGCCTGAAAAATGGGCACGATTCTA
TACTGCAGAAGTAGTTCTTGCATTGGATGCAATCCATTCCATGGGTTTTATTCACAGAGATGTGAAGCCTGATAACATGCTGCTGGATAA
ATCTGGACATTTGAAGTTAGCAGATTTTGGTACTTGTATGAAGATGAATAAGGAAGGCATGGTACGATGTGATACAGCGGTTGGAACACC
TGATTATATTTCCCCTGAAGTATTAAAATCCCAAGGTGGTGATGGTTATTATGGAAGAGAATGTGACTGGTGGTCGGTTGGGGTATTTTT
ATACGAAATGCTTGTAGGTGATACACCTTTTTATGCAGATTCTTTGGTTGGAACTTACAGTAAAATTATGAACCATAAAAATTCACTTAC
CTTTCCTGATGATAATGACATATCAAAAGAAGCAAAAAACCTTATTTGTGCCTTCCTTACTGACAGGGAAGTGAGGTTAGGGCGAAATGG
TGTAGAAGAAATCAAACGACATCTCTTCTTCAAAAATGACCAGTGGGCTTGGGAAACGCTCCGAGACACTGTAGCACCAGTTGTACCCGA
TTTAAGTAGTGACATTGATACTAGTAATTTTGATGACTTGGAAGAAGATAAAGGAGAGGAAGAAACATTCCCTATTCCTAAAGCTTTCGT
TGGCAATCAACTACCTTTTGTAGGATTTACATATTATAGCAATCGTAGATACTTATCTTCAGCAAATCCTAATGATAACAGAACTAGCTC
CAATGCAGATAAAAGCTTGCAGGAAAGTTTGCAAAAAACAATCTATAAGCTGGAAGAACAGCTGCATAATGAAATGCAGTTAAAAGATGA
AATGGAGCAGAAGTGCAGAACCTCAAACATAAAACTAGACAAGATAATGAAAGAATTGGATGAAGAGGGAAATCAAAGAAGAAATCTAGA
ATCTACAGTGTCTCAGATTGAGAAGGAGAAAATGTTGCTACAGCATAGAATTAATGAGTACCAAAGAAAAGCTGAACAGGAAAATGAGAA
GAGAAGAAATGTAGAAAATGAAGTTTCTACATTAAAGGATCAGTTGGAAGACTTAAAGAAAGTCAGTCAGAATTCACAGCTTGCTAATGA
GAAGCTGTCCCAGTTACAAAAGCAGCTAGAAGAAGCCAATGACTTACTTAGGACAGAATCGGACACAGCTGTAAGATTGAGGAAGAGTCA
CACAGAGATGAGCAAGTCAATTAGTCAGTTAGAGTCCCTGAACAGAGAGTTGCAAGAGAGAAATCGAATTTTAGAGAATTCTAAGTCACA
AACAGACAAAGATTATTACCAGCTGCAAGCTATATTAGAAGCTGAACGAAGAGACAGAGGTCATGATTCTGAGATGATTGGAGACCTTCA
AGCTCGAATTACATCTTTACAAGAGGAGGTGAAGCATCTCAAACATAATCTCGAAAAAGTGGAAGGAGAAAGAAAAGAGGCTCAAGACAT
GCTTAATCACTCAGAAAAGGAAAAGAATAATTTAGAGATAGATTTAAACTACAAACTTAAATCATTACAACAACGGTTAGAACAAGAGGT
AAATGAACACAAAGTAACCAAAGCTCGTTTAACTGACAAACATCAATCTATTGAAGAGGCAAAGTCTGTGGCAATGTGTGAGATGGAAAA
AAAGCTGAAAGAAGAAAGAGAAGCTCGAGAGAAGGCTGAAAATCGGGTTGTTCAGATTGAGAAACAGTGTTCCATGCTAGACGTTGATCT
GAAGCAATCTCAGCAGAAACTAGAACATTTGACTGGAAATAAAGAAAGGATGGAGGATGAAGTTAAGAATCTAACCCTGCAACTGGAGCA
GGAATCAAATAAGCGGCTGTTGTTACAAAATGAATTGAAGACTCAAGCATTTGAGGCAGACAATTTAAAAGGTTTAGAAAAGCAGATGAA
ACAGGAAATAAATACTTTATTGGAAGCAAAGAGATTATTAGAATTTGAGTTAGCTCAGCTTACGAAACAGTATAGAGGAAATGAAGGACA
GATGCGGGAGCTACAAGATCAGCTTGAAGCTGAGCAATATTTCTCGACACTTTATAAAACCCAGGTAAAGGAACTTAAAGAAGAAATTGA
AGAAAAAAACAGAGAAAATTTAAAGAAAATACAGGAACTACAAAATGAAAAAGAAACTCTTGCTACTCAGTTGGATCTAGCAGAAACAAA
AGCTGAGTCTGAGCAGTTGGCGCGAGGCCTTCTGGAAGAACAGTATTTTGAATTGACGCAAGAAAGCAAGAAAGCTGCTTCAAGAAATAG
ACAAGAGATTACAGATAAAGATCACACTGTTAGTCGGCTTGAAGAAGCAAACAGCATGCTAACCAAAGATATTGAAATATTAAGAAGAGA
GAATGAAGAGCTAACAGAGAAAATGAAGAAGGCAGAGGAAGAATATAAACTGGAGAAGGAGGAGGAGATCAGTAATCTTAAGGCTGCCTT
TGAAAAGAATATCAACACTGAACGAACCCTTAAAACACAGGCTGTTAACAAATTGGCAGAAATAATGAATCGAAAAGATTTTAAAATTGA
TAGAAAGAAAGCTAATACACAAGATTTGAGAAAGAAAGAAAAGGAAAATCGAAAGCTGCAACTGGAACTCAACCAAGAAAGAGAGAAATT
CAACCAGATGGTAGTGAAACATCAGAAGGAACTGAATGACATGCAAGCGCAATTGGTAGAAGAATGTGCACATAGGAATGAGCTTCAGAT
GCAGTTGGCCAGCAAAGAGAGTGATATTGAGCAATTGCGTGCTAAACTTTTGGACCTCTCGGATTCTACAAGTGTTGCTAGTTTTCCTAG
TGCTGATGAAACTGATGGTAACCTCCCAGAGTCAAGAATTGAAGGTTGGCTTTCAGTACCAAATAGAGGAAATATCAAACGATATGGCTG
GAAGAAACAGTATGTTGTGGTAAGCAGCAAAAAAATTTTGTTCTATAATGACGAACAAGATAAGGAGCAATCCAATCCATCTATGGTATT
GGACATAGATAAACTGTTTCACGTTAGACCTGTAACCCAAGGAGATGTGTATAGAGCTGAAACTGAAGAAATTCCTAAAATATTCCAGAT
ACTATATGCAAATGAAGGTGAATGTAGAAAAGATGTAGAGATGGAACCAGTACAACAAGCTGAAAAAACTAATTTCCAAAATCACAAAGG
CCATGAGTTTATTCCTACACTCTACCACTTTCCTGCCAATTGTGATGCCTGTGCCAAACCTCTCTGGCATGTTTTTAAGCCACCCCCTGC
CCTAGAGTGTCGAAGATGCCATGTTAAGTGCCACAGAGATCACTTAGATAAGAAAGAGGACTTAATTTGTCCATGTAAAGTAAGTTATGA
TGTAACATCAGCAAGAGATATGCTGCTGTTAGCATGTTCTCAGGATGAACAAAAAAAATGGGTAACTCATTTAGTAAAGAAAATCCCTAA
GAATCCACCATCTGGTTTTGTTCGTGCTTCCCCTCGAACGCTTTCTACAAGATCCACTGCAAATCAGTCTTTCCGGAAAGTGGTCAAAAA
TACATCTGGAAAAACTAGTTAACCATGTGACTGAGTGCCCTGTGGAATCGTGTGGGATGCTACCTGATAAACCAGGCTTCTTTAACCATG
CAGAGCAGACAGGCTGTTTCTTTGACACAAATATCACAGGCTTCAGGGTTAAGATTGCTGTTTTTCTGTCCTTGCTTTGGCACAACACAC
TGAGGGTTTTTTTTATTGCGGGTTTGCCTACAGGTAGATTAGATTAATTATTACTATGTAATGCAAGTACAGTTGGGGGAAAGCTTAGGT
AGATATATTTTTTTTAAAAGGTGCTGCCTTTTTGGATTTATAAGAAAATGCCTGTCAGTCGTGATAGAACAGAGTTTTCCTCATATGAGT
AAGAGGAAGGGACTTTCACTTTCAAGTGGAACAGCCATCACTATCAAGATCAGCTCATGGAAGGAGTAAAGAAAATATCTCAAAATGAGA
CAAACTGAAGTTTTGTTTTTTTTTTAATGACTTAAGTTTTTGTGCTCTTGCAAGACTATACAAAACTATTTTAAGAAAGCAGTGATATCA
CTTGAACTTCAGTGCCCTCACTGTAGAATTTAAAAGCCTTACTGTTGATTGCCCATGTTGGACTTGATGGAGAAATTAAATATCTTTCAT
TATGCTTTACAAAATACTGTATATGTTTCAGCAAGTTTGGGGAATGGGAGAGGACAAAAAAAAGTTACATTTAATCTATGCATTTTTGCC
AAGCCATATTGAGTTATTTTACTACTAGAGACATTAGGAAACTAACTGTACAAAAGAACCAAGTTTAAAAGCATTTTGTGGGGTACATCA
TTTCTATAATTGTATAATGTATTTCTTTGTGGTTTTAAATGATAAAGACATTAAGTTAACAAACATATAAGAAATGTATGCACTGTTTGA
AATGTAAATTATTCTTAGAACACTTTCAATGGGGGTTGCATTGTCCTTTTAGTGCCTTAATTTGAGATAATTATTTTACTGCCATGAGTA
AGTATAGAAATTTCAAAAAATGTATTTTCAAAAAATTATGTGTGTCAGTGAGTTTTTCATTGATAATTGGTTTAATTTAAAATATTTAGA
GGTTTGTTGGACTTTCATAAATTGAGTACAATCTTTGCATCAAACTACCTGCTACAATAATGACTTTATAAAACTGCAAAAAATGTAGAA
GGTTGCACCAACATAAAAAGGAAATATGGCAATACATCCATGATGTTTTCCAGTTAACATAGGAATTACCAGATAAATACTGTTAAACTC
TTGTCCAGTAACAAGAGTTGATTCATATGGACAGTATGATTTATTGTTTATTTTTTTAACCAAATACCTCCTCAGTAATTTATAATGGCT
TTGCAGTAATGTGTATCAGATAAGAAGCACTGGAAAACCGATCGTCTCTAGGATGATATGCATGTTTCAAGTGGTATTGAAAGCCGCACT
GATGGATATGTAATAATAAACATATCTGTTATTAATATACTAATGACTCTGTGCTCATTTAATGAGAAATAAAAGTAATTTATGGATGGG
TATCTTTAATTTTTACTGCAATGTGTTTTCTCATGGCTGAAATGAATGGAAAACATACTTCAAATTAGTCTCTGATTGTATATAAATGTT
TGTGAAATTCCATGGTTAGATTAAAGTGTATTTTTAAAAGATAAAACGTGGTCTTGGGCTCTAAAACAAGAGTGGGAATAGTTCACATGA
AAAGCTGGCTAAAGTGTGTTGGAAAACAATTCTCCATGGGTCTCTTGCATTTCTACACATCAGGGAAGCAGAGGCTCTGACAACCTTTCT
TTTGACTATCTTTTCCAAGGATATTTATGTAGTAAACAGCCTTGGAAGATAGAGTTCTCCCTTGTGAGGATGTCGGGTTCTTTTACTGTC
CAGTATAATAAAGATAACGTCTCCCACCTATGATGCAAACCCACTGTGTGCTCAGCACCCACCTGGGCCACTCTGCATTGCCCACATGGG
GCTTGGAGGGCAAAGGGAACTGATGGAACGTGAAACTTATGCTGCTTTTGCTGTGCTGTGAATGAAGTCATCTGACTCTGACCCAGGGGT
CTCATCTCTTTTGTCAGGATCCATGAAACTGTGACTGGCAGCATGCAAACAGGATAAAATCTCAGCACAGTTCCTGACGGTGTCCTTACT
ACCTTCTCAGACTCATCACCATTACCTAATATTTTAAGGTCCAGTTGCAGAGAACAGAGTTAATTCTAATTAGTTTAAGCAAGAGAAGAC
TTTCCAAATGACATACTAATCTGAACTTAGAATTGTTGAGAACTGAGAGAGCTTTGAGGAATCACTCCCAATGCCACATTACAGAACTGG
GTCAACCAGGAGAGCTGCTTCCTCTTCTAAGTTCAGGAAACCACTCACTCCCAAGTATACCAATATTGAGAGGGTCCAGATAGTGCCATA
ATCAGGAATCCACACTACCACTGCTGGTTCTCTGCAACACTTGTCAGGCTTGCTACAATCTACCTCCAGTTAGATGTTTTGTACCATTCC
TCTTGCCACTTAAGAACCTCATGTCTGCACACTGCCTCAGAAAAGGCACTTCCATGACCCTGCTTGCTGGCATTTAGCACAGCCTGCATC
TCACGTCTGCCTTCTCTAGGTGCATCTACGTGGCCAAAATTAAATCACATCCAGACCCCTAGCTGCAAGAAAGTCTGAGAAATATAGCCT
CTAGCTTTCTCTCTAATTTGTTACAGGAGGACACACTAGGAGTGTGGAATGAAGGTTCAGCATTGAGTTAGCCCATGCACCCACACCTGT
AAGCTTCTCTGAGATCAGGAACTCCAGCTTTGGGCAACAAAGAAAACATAGCCACTGTCATTATTCACAGGTTCACTCATGACCTGTCAT
TTGGGGTTTCAGCTTAAATTAACCCATTCACCCTTCATTTAAAGTAAAAAAAATAAGTAAAAGAACTTAAATGACAAACTCATAGTTACT
TGAGTTTGTAATTCATAGTTAACTTTCACAGTTCTATAATCAATCTGGAATTCAGAGTGAGGTAGAGATCAAGCAGTATTTCTCCCATAT
GGATATTCAGTTGATACTGCAGTATTCATTGAAAATACTTCTTTCCTGCATCGTAATTCAGGTGAACAATCCATTGGTGTTATTTCTGTG
TCCTTGCCAATATCACACTTTTAATTACTGTAACTTTATAATAAGATTTTATATCTGTAGTAGAAGTCCAACTTTGTAATCCCTCCCAAT
TGGCTTGGCTATTCTTGGCCTTTTGCATTTCCATATAATTTTTTATTTTTGTTTTGAAACGAAGTTTCGCTCTTGTTGCCCAGGCTGGAG
TGCAGTGGCGCGATCTCGGCTCACTGCAACCTCCGCCTCCCAGGTTCAAGTGATCCTCCTGCCTCAGACTCCCGAGTAGCTGGGATTACA
GGTGCCCACCACCATGCCCAGCTAATTTTTGTATTTTTAGTAGAGACAGGGTTTCACCATGTTGGCCAGCCTGGTCTTGAACTCCTGACC
TCAGGTGATCCACACCCACCTTGGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACCGCGCCTGGTTGCATTCCCATATAAATTTAA
AAACAATCTACTGAAAGATGTATACGACCTCCACCAAGAAAATTGTAAGACATTTGGAGAAGTTTAAAAAGACATGAATAAACGGAAATG
GTTTTTTTAAATAAACAAATGATTTTTAAAGTTGATCATTAGGTTAATAAATAGTCATATAATGACAATCCGATGAGATTATGTTGCCCA
GGGTGGTCTCTAACTCCTAGCCTCAAGCAGTTTTACTCTCTCATTACAGGTGTAGGCCACCGTGCCTGGCCTGACACTTGGAAATCTTAA
TCACAATTATTCTTTGTTTTTATAATGTTTACTGTTCAAATCAATTTCTGGTTGGATAGTATGTATATATAAAGCCATGCTCAATGGCCT
AGATATATTTACTGCCAAATCTTTTATGCTTTTAGTGTTTTTTTTCTGGACAAGATCTATGCTTATTGCAATAAATTAAATGCAAAGAAT
ATTCTAGTAGAAAGTCAGTCTGCACTTCCTAAACCCCACCCCACCCCACCAATTCCTTCATAACTGTTATTAACAGTTAGCTGTGTTTTC
TAATGGATTATCTCCAAAGTATATGTAACTCAGATTTTTGTGAGGTAGGAAAAGAATAACATTAATTCCACTTCACATATTGAAAGTCTA
ACATACAAAGAGATTAAATATCTCCTTTCTTTTGCCAAATGTTAATGAATTGTCTTATGAGAATTAAGATATGATACTTTCTCCCAAGCT
ATACTGTTTCCCATAAAGTATTTGAGATGTTGGAGATTCAAGGGAAAAAATATAAATGCTTAGAAATAAAGTGTATAATGCAAAGATTGT
GAATAAAGTGACACTTGTATGTTAATCCTATAAATTGGTTTCTTGTACCATGTAGGATGGTTTGGCTATTAAATTGAATTAAGTGGTTCA

>In-frame_GNE_ENST00000377902_chr9_36236829_-_ROCK1_ENST00000399799_chr18_18650574_-_9440nt
GTGGGCGTGGCTGGGCGAGCGAGGAGTGGGGACAAGGTCGAGCGACGAGTCGTCTACCCGCGCGCCCGAGCGCGGAAACCGAGGGGCAGG
CTCGCGCTCTGCCTGCTTCGTGGCGCTTGGTTCGTCCCTCGCCCGAGGAGCGCGGTGGCGGCGTGGGAGGGAGCCTCTGACGGCGTCTGG
AACTCTATTTTAAGAACCTCTCAAAACGAAACAAGCAAATCATGGAGAAGAATGGAAATAACCGAAAGCTGCGGGTTTGTGTTGCTACTT
GTAACCGTGCAGATTATTCTAAACTTGCCCCGATCATGTTTGGCATTAAAACCGAACCTGAGTTCTTTGAACTTGATGTTGTGGTACTTG
GCTCTCACCTGATAGATGACTATGGAAATACATATCGAATGATTGAACAAGATGACTTTGACATTAACACCAGGCTACACACAATTGTGA
GGGGAGAAGATGAGGCAGCCATGGTGGAGTCAGTAGGCCTGGCCCTAGTGAAGCTGCCAGATGTCCTTAATCGCCTGAAGCCTGATATCA
TGATTGTTCATGGAGACAGGTTTGATGCCCTGGCTCTGGCCACATCTGCTGCCTTGATGAACATCCGAATCCTTCACATTGAAGGTGGGG
AAGTCAGTGGGACCATTGATGACTCTATCAGACATGCCATAACAAAACTGGCTCATTATCATGTGTGCTGCACCCGCAGTGCAGAGCAGC
ACCTGATATCCATGTGTGAGGACCATGATCGCATCCTTTTGGCAGGCTGCCCTTCCTATGACAAACTTCTCTCAGCCAAGAACAAAGACT
ACATGAGCATCATTCGCATGTGGCTAGGTGATGATGTAAAATCTAAAGATTACATTGTTGCACTACAGCACCCTGTGACCACTGACATTA
AGCATTCCATAAAAATGTTTGAATTAACATTGGATGCACTTATCTCATTTAACAAGCGGACCCTAGTCCTGTTTCCAAATATTGACGCAG
GATGGATTGGATGCTTTGGTATATGATTTGGATTTTCCTGCCTTAAGAAAAAACAAAAATATTGACAACTTTTTAAGCAGATATAAAGAC
ACAATAAATAAAATCAGAGATTTACGAATGAAAGCTGAAGATTATGAAGTAGTGAAGGTGATTGGTAGAGGTGCATTTGGAGAAGTTCAA
TTGGTAAGGCATAAATCCACCAGGAAGGTATATGCTATGAAGCTTCTCAGCAAATTTGAAATGATAAAGAGATCTGATTCTGCTTTTTTC
TGGGAAGAAAGGGACATCATGGCTTTTGCCAACAGTCCTTGGGTTGTTCAGCTTTTTTATGCATTCCAAGATGATCGTTATCTCTACATG
GTGATGGAATACATGCCTGGTGGAGATCTTGTAAACTTAATGAGCAACTATGATGTGCCTGAAAAATGGGCACGATTCTATACTGCAGAA
GTAGTTCTTGCATTGGATGCAATCCATTCCATGGGTTTTATTCACAGAGATGTGAAGCCTGATAACATGCTGCTGGATAAATCTGGACAT
TTGAAGTTAGCAGATTTTGGTACTTGTATGAAGATGAATAAGGAAGGCATGGTACGATGTGATACAGCGGTTGGAACACCTGATTATATT
TCCCCTGAAGTATTAAAATCCCAAGGTGGTGATGGTTATTATGGAAGAGAATGTGACTGGTGGTCGGTTGGGGTATTTTTATACGAAATG
CTTGTAGGTGATACACCTTTTTATGCAGATTCTTTGGTTGGAACTTACAGTAAAATTATGAACCATAAAAATTCACTTACCTTTCCTGAT
GATAATGACATATCAAAAGAAGCAAAAAACCTTATTTGTGCCTTCCTTACTGACAGGGAAGTGAGGTTAGGGCGAAATGGTGTAGAAGAA
ATCAAACGACATCTCTTCTTCAAAAATGACCAGTGGGCTTGGGAAACGCTCCGAGACACTGTAGCACCAGTTGTACCCGATTTAAGTAGT
GACATTGATACTAGTAATTTTGATGACTTGGAAGAAGATAAAGGAGAGGAAGAAACATTCCCTATTCCTAAAGCTTTCGTTGGCAATCAA
CTACCTTTTGTAGGATTTACATATTATAGCAATCGTAGATACTTATCTTCAGCAAATCCTAATGATAACAGAACTAGCTCCAATGCAGAT
AAAAGCTTGCAGGAAAGTTTGCAAAAAACAATCTATAAGCTGGAAGAACAGCTGCATAATGAAATGCAGTTAAAAGATGAAATGGAGCAG
AAGTGCAGAACCTCAAACATAAAACTAGACAAGATAATGAAAGAATTGGATGAAGAGGGAAATCAAAGAAGAAATCTAGAATCTACAGTG
TCTCAGATTGAGAAGGAGAAAATGTTGCTACAGCATAGAATTAATGAGTACCAAAGAAAAGCTGAACAGGAAAATGAGAAGAGAAGAAAT
GTAGAAAATGAAGTTTCTACATTAAAGGATCAGTTGGAAGACTTAAAGAAAGTCAGTCAGAATTCACAGCTTGCTAATGAGAAGCTGTCC
CAGTTACAAAAGCAGCTAGAAGAAGCCAATGACTTACTTAGGACAGAATCGGACACAGCTGTAAGATTGAGGAAGAGTCACACAGAGATG
AGCAAGTCAATTAGTCAGTTAGAGTCCCTGAACAGAGAGTTGCAAGAGAGAAATCGAATTTTAGAGAATTCTAAGTCACAAACAGACAAA
GATTATTACCAGCTGCAAGCTATATTAGAAGCTGAACGAAGAGACAGAGGTCATGATTCTGAGATGATTGGAGACCTTCAAGCTCGAATT
ACATCTTTACAAGAGGAGGTGAAGCATCTCAAACATAATCTCGAAAAAGTGGAAGGAGAAAGAAAAGAGGCTCAAGACATGCTTAATCAC
TCAGAAAAGGAAAAGAATAATTTAGAGATAGATTTAAACTACAAACTTAAATCATTACAACAACGGTTAGAACAAGAGGTAAATGAACAC
AAAGTAACCAAAGCTCGTTTAACTGACAAACATCAATCTATTGAAGAGGCAAAGTCTGTGGCAATGTGTGAGATGGAAAAAAAGCTGAAA
GAAGAAAGAGAAGCTCGAGAGAAGGCTGAAAATCGGGTTGTTCAGATTGAGAAACAGTGTTCCATGCTAGACGTTGATCTGAAGCAATCT
CAGCAGAAACTAGAACATTTGACTGGAAATAAAGAAAGGATGGAGGATGAAGTTAAGAATCTAACCCTGCAACTGGAGCAGGAATCAAAT
AAGCGGCTGTTGTTACAAAATGAATTGAAGACTCAAGCATTTGAGGCAGACAATTTAAAAGGTTTAGAAAAGCAGATGAAACAGGAAATA
AATACTTTATTGGAAGCAAAGAGATTATTAGAATTTGAGTTAGCTCAGCTTACGAAACAGTATAGAGGAAATGAAGGACAGATGCGGGAG
CTACAAGATCAGCTTGAAGCTGAGCAATATTTCTCGACACTTTATAAAACCCAGGTAAAGGAACTTAAAGAAGAAATTGAAGAAAAAAAC
AGAGAAAATTTAAAGAAAATACAGGAACTACAAAATGAAAAAGAAACTCTTGCTACTCAGTTGGATCTAGCAGAAACAAAAGCTGAGTCT
GAGCAGTTGGCGCGAGGCCTTCTGGAAGAACAGTATTTTGAATTGACGCAAGAAAGCAAGAAAGCTGCTTCAAGAAATAGACAAGAGATT
ACAGATAAAGATCACACTGTTAGTCGGCTTGAAGAAGCAAACAGCATGCTAACCAAAGATATTGAAATATTAAGAAGAGAGAATGAAGAG
CTAACAGAGAAAATGAAGAAGGCAGAGGAAGAATATAAACTGGAGAAGGAGGAGGAGATCAGTAATCTTAAGGCTGCCTTTGAAAAGAAT
ATCAACACTGAACGAACCCTTAAAACACAGGCTGTTAACAAATTGGCAGAAATAATGAATCGAAAAGATTTTAAAATTGATAGAAAGAAA
GCTAATACACAAGATTTGAGAAAGAAAGAAAAGGAAAATCGAAAGCTGCAACTGGAACTCAACCAAGAAAGAGAGAAATTCAACCAGATG
GTAGTGAAACATCAGAAGGAACTGAATGACATGCAAGCGCAATTGGTAGAAGAATGTGCACATAGGAATGAGCTTCAGATGCAGTTGGCC
AGCAAAGAGAGTGATATTGAGCAATTGCGTGCTAAACTTTTGGACCTCTCGGATTCTACAAGTGTTGCTAGTTTTCCTAGTGCTGATGAA
ACTGATGGTAACCTCCCAGAGTCAAGAATTGAAGGTTGGCTTTCAGTACCAAATAGAGGAAATATCAAACGATATGGCTGGAAGAAACAG
TATGTTGTGGTAAGCAGCAAAAAAATTTTGTTCTATAATGACGAACAAGATAAGGAGCAATCCAATCCATCTATGGTATTGGACATAGAT
AAACTGTTTCACGTTAGACCTGTAACCCAAGGAGATGTGTATAGAGCTGAAACTGAAGAAATTCCTAAAATATTCCAGATACTATATGCA
AATGAAGGTGAATGTAGAAAAGATGTAGAGATGGAACCAGTACAACAAGCTGAAAAAACTAATTTCCAAAATCACAAAGGCCATGAGTTT
ATTCCTACACTCTACCACTTTCCTGCCAATTGTGATGCCTGTGCCAAACCTCTCTGGCATGTTTTTAAGCCACCCCCTGCCCTAGAGTGT
CGAAGATGCCATGTTAAGTGCCACAGAGATCACTTAGATAAGAAAGAGGACTTAATTTGTCCATGTAAAGTAAGTTATGATGTAACATCA
GCAAGAGATATGCTGCTGTTAGCATGTTCTCAGGATGAACAAAAAAAATGGGTAACTCATTTAGTAAAGAAAATCCCTAAGAATCCACCA
TCTGGTTTTGTTCGTGCTTCCCCTCGAACGCTTTCTACAAGATCCACTGCAAATCAGTCTTTCCGGAAAGTGGTCAAAAATACATCTGGA
AAAACTAGTTAACCATGTGACTGAGTGCCCTGTGGAATCGTGTGGGATGCTACCTGATAAACCAGGCTTCTTTAACCATGCAGAGCAGAC
AGGCTGTTTCTTTGACACAAATATCACAGGCTTCAGGGTTAAGATTGCTGTTTTTCTGTCCTTGCTTTGGCACAACACACTGAGGGTTTT
TTTTATTGCGGGTTTGCCTACAGGTAGATTAGATTAATTATTACTATGTAATGCAAGTACAGTTGGGGGAAAGCTTAGGTAGATATATTT
TTTTTAAAAGGTGCTGCCTTTTTGGATTTATAAGAAAATGCCTGTCAGTCGTGATAGAACAGAGTTTTCCTCATATGAGTAAGAGGAAGG
GACTTTCACTTTCAAGTGGAACAGCCATCACTATCAAGATCAGCTCATGGAAGGAGTAAAGAAAATATCTCAAAATGAGACAAACTGAAG
TTTTGTTTTTTTTTTAATGACTTAAGTTTTTGTGCTCTTGCAAGACTATACAAAACTATTTTAAGAAAGCAGTGATATCACTTGAACTTC
AGTGCCCTCACTGTAGAATTTAAAAGCCTTACTGTTGATTGCCCATGTTGGACTTGATGGAGAAATTAAATATCTTTCATTATGCTTTAC
AAAATACTGTATATGTTTCAGCAAGTTTGGGGAATGGGAGAGGACAAAAAAAAGTTACATTTAATCTATGCATTTTTGCCAAGCCATATT
GAGTTATTTTACTACTAGAGACATTAGGAAACTAACTGTACAAAAGAACCAAGTTTAAAAGCATTTTGTGGGGTACATCATTTCTATAAT
TGTATAATGTATTTCTTTGTGGTTTTAAATGATAAAGACATTAAGTTAACAAACATATAAGAAATGTATGCACTGTTTGAAATGTAAATT
ATTCTTAGAACACTTTCAATGGGGGTTGCATTGTCCTTTTAGTGCCTTAATTTGAGATAATTATTTTACTGCCATGAGTAAGTATAGAAA
TTTCAAAAAATGTATTTTCAAAAAATTATGTGTGTCAGTGAGTTTTTCATTGATAATTGGTTTAATTTAAAATATTTAGAGGTTTGTTGG
ACTTTCATAAATTGAGTACAATCTTTGCATCAAACTACCTGCTACAATAATGACTTTATAAAACTGCAAAAAATGTAGAAGGTTGCACCA
ACATAAAAAGGAAATATGGCAATACATCCATGATGTTTTCCAGTTAACATAGGAATTACCAGATAAATACTGTTAAACTCTTGTCCAGTA
ACAAGAGTTGATTCATATGGACAGTATGATTTATTGTTTATTTTTTTAACCAAATACCTCCTCAGTAATTTATAATGGCTTTGCAGTAAT
GTGTATCAGATAAGAAGCACTGGAAAACCGATCGTCTCTAGGATGATATGCATGTTTCAAGTGGTATTGAAAGCCGCACTGATGGATATG
TAATAATAAACATATCTGTTATTAATATACTAATGACTCTGTGCTCATTTAATGAGAAATAAAAGTAATTTATGGATGGGTATCTTTAAT
TTTTACTGCAATGTGTTTTCTCATGGCTGAAATGAATGGAAAACATACTTCAAATTAGTCTCTGATTGTATATAAATGTTTGTGAAATTC
CATGGTTAGATTAAAGTGTATTTTTAAAAGATAAAACGTGGTCTTGGGCTCTAAAACAAGAGTGGGAATAGTTCACATGAAAAGCTGGCT
AAAGTGTGTTGGAAAACAATTCTCCATGGGTCTCTTGCATTTCTACACATCAGGGAAGCAGAGGCTCTGACAACCTTTCTTTTGACTATC
TTTTCCAAGGATATTTATGTAGTAAACAGCCTTGGAAGATAGAGTTCTCCCTTGTGAGGATGTCGGGTTCTTTTACTGTCCAGTATAATA
AAGATAACGTCTCCCACCTATGATGCAAACCCACTGTGTGCTCAGCACCCACCTGGGCCACTCTGCATTGCCCACATGGGGCTTGGAGGG
CAAAGGGAACTGATGGAACGTGAAACTTATGCTGCTTTTGCTGTGCTGTGAATGAAGTCATCTGACTCTGACCCAGGGGTCTCATCTCTT
TTGTCAGGATCCATGAAACTGTGACTGGCAGCATGCAAACAGGATAAAATCTCAGCACAGTTCCTGACGGTGTCCTTACTACCTTCTCAG
ACTCATCACCATTACCTAATATTTTAAGGTCCAGTTGCAGAGAACAGAGTTAATTCTAATTAGTTTAAGCAAGAGAAGACTTTCCAAATG
ACATACTAATCTGAACTTAGAATTGTTGAGAACTGAGAGAGCTTTGAGGAATCACTCCCAATGCCACATTACAGAACTGGGTCAACCAGG
AGAGCTGCTTCCTCTTCTAAGTTCAGGAAACCACTCACTCCCAAGTATACCAATATTGAGAGGGTCCAGATAGTGCCATAATCAGGAATC
CACACTACCACTGCTGGTTCTCTGCAACACTTGTCAGGCTTGCTACAATCTACCTCCAGTTAGATGTTTTGTACCATTCCTCTTGCCACT
TAAGAACCTCATGTCTGCACACTGCCTCAGAAAAGGCACTTCCATGACCCTGCTTGCTGGCATTTAGCACAGCCTGCATCTCACGTCTGC
CTTCTCTAGGTGCATCTACGTGGCCAAAATTAAATCACATCCAGACCCCTAGCTGCAAGAAAGTCTGAGAAATATAGCCTCTAGCTTTCT
CTCTAATTTGTTACAGGAGGACACACTAGGAGTGTGGAATGAAGGTTCAGCATTGAGTTAGCCCATGCACCCACACCTGTAAGCTTCTCT
GAGATCAGGAACTCCAGCTTTGGGCAACAAAGAAAACATAGCCACTGTCATTATTCACAGGTTCACTCATGACCTGTCATTTGGGGTTTC
AGCTTAAATTAACCCATTCACCCTTCATTTAAAGTAAAAAAAATAAGTAAAAGAACTTAAATGACAAACTCATAGTTACTTGAGTTTGTA
ATTCATAGTTAACTTTCACAGTTCTATAATCAATCTGGAATTCAGAGTGAGGTAGAGATCAAGCAGTATTTCTCCCATATGGATATTCAG
TTGATACTGCAGTATTCATTGAAAATACTTCTTTCCTGCATCGTAATTCAGGTGAACAATCCATTGGTGTTATTTCTGTGTCCTTGCCAA
TATCACACTTTTAATTACTGTAACTTTATAATAAGATTTTATATCTGTAGTAGAAGTCCAACTTTGTAATCCCTCCCAATTGGCTTGGCT
ATTCTTGGCCTTTTGCATTTCCATATAATTTTTTATTTTTGTTTTGAAACGAAGTTTCGCTCTTGTTGCCCAGGCTGGAGTGCAGTGGCG
CGATCTCGGCTCACTGCAACCTCCGCCTCCCAGGTTCAAGTGATCCTCCTGCCTCAGACTCCCGAGTAGCTGGGATTACAGGTGCCCACC
ACCATGCCCAGCTAATTTTTGTATTTTTAGTAGAGACAGGGTTTCACCATGTTGGCCAGCCTGGTCTTGAACTCCTGACCTCAGGTGATC
CACACCCACCTTGGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACCGCGCCTGGTTGCATTCCCATATAAATTTAAAAACAATCTA
CTGAAAGATGTATACGACCTCCACCAAGAAAATTGTAAGACATTTGGAGAAGTTTAAAAAGACATGAATAAACGGAAATGGTTTTTTTAA
ATAAACAAATGATTTTTAAAGTTGATCATTAGGTTAATAAATAGTCATATAATGACAATCCGATGAGATTATGTTGCCCAGGGTGGTCTC
TAACTCCTAGCCTCAAGCAGTTTTACTCTCTCATTACAGGTGTAGGCCACCGTGCCTGGCCTGACACTTGGAAATCTTAATCACAATTAT
TCTTTGTTTTTATAATGTTTACTGTTCAAATCAATTTCTGGTTGGATAGTATGTATATATAAAGCCATGCTCAATGGCCTAGATATATTT
ACTGCCAAATCTTTTATGCTTTTAGTGTTTTTTTTCTGGACAAGATCTATGCTTATTGCAATAAATTAAATGCAAAGAATATTCTAGTAG
AAAGTCAGTCTGCACTTCCTAAACCCCACCCCACCCCACCAATTCCTTCATAACTGTTATTAACAGTTAGCTGTGTTTTCTAATGGATTA
TCTCCAAAGTATATGTAACTCAGATTTTTGTGAGGTAGGAAAAGAATAACATTAATTCCACTTCACATATTGAAAGTCTAACATACAAAG
AGATTAAATATCTCCTTTCTTTTGCCAAATGTTAATGAATTGTCTTATGAGAATTAAGATATGATACTTTCTCCCAAGCTATACTGTTTC
CCATAAAGTATTTGAGATGTTGGAGATTCAAGGGAAAAAATATAAATGCTTAGAAATAAAGTGTATAATGCAAAGATTGTGAATAAAGTG


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FusionGenePPI for GNE_ROCK1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page

.

check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors
GNEELAVL1, GABPA, RBM12, KCTD12, RAB3GAP1, RAB3GAP2, SMARCAD1, TSEN34, KRTAP5-9, KRT31, GNE, SPRY2, ADAMTSL4, KRTAP4-12, KRTAP9-2, GTPBP3, KRTAP10-7, KRTAP10-9, KRTAP10-5, KRTAP10-8, KRTAP10-3, NOTCH2NL, C2orf68, NTRK1, LGALS3BP, ZNF764, TIMM50ROCK1CDC25A, PFN2, RHOA, RND3, GAB1, CFL1, LIMK2, HNRNPA1, ITSN2, ARRB1, TSG101, NOTCH1, SMURF1, SMAD2, CASP3, CASP7, CDK15, ANKFY1, MON2, FAM21A, KIAA1033, IKBKB, LMO2, MAGEB4, POLR3C, C6orf165, FAM124A, NXF1, NTRK1, MED23, XRCC5, NEIL3, TRIM15, HGS, SLC9A1, UBE2T, CDKN3, TENC1, ROCK2, ADD2, IL20RA, CYLD


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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RelatedDrugs for GNE_ROCK1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for GNE_ROCK1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneGNEC1853926NONAKA MYOPATHY12CTD_human;ORPHANET;UNIPROT
HgeneGNEC0342853Sialuria3CTD_human;UNIPROT
HgeneGNEC0238190Inclusion Body Myositis (disorder)1CTD_human
HgeneGNEC1833373Inclusion Body Myopathy, Autosomal Recessive1CTD_human