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Fusion gene ID: 14869 |
FusionGeneSummary for GNAS_CPB1 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: GNAS_CPB1 | Fusion gene ID: 14869 | Hgene | Tgene | Gene symbol | GNAS | CPB1 | Gene ID | 2778 | 1360 |
| Gene name | GNAS complex locus | carboxypeptidase B1 | |
| Synonyms | AHO|C20orf45|GNAS1|GPSA|GSA|GSP|NESP|PITA3|POH|SCG6|SgVI | CPB|PASP|PCPB | |
| Cytomap | 20q13.32 | 3q24 | |
| Type of gene | protein-coding | protein-coding | |
| Description | protein ALEXprotein GNASprotein SCG6 (secretogranin VI)G protein subunit alpha Sadenylate cyclase-stimulating G alpha proteinalternative gene product encoded by XL-exonextra large alphas proteinguanine nucleotide binding protein (G protein), alpha | carboxypeptidase Bcarboxypeptidase B1 (tissue)pancreas-specific proteinpancreatic carboxypeptidase Bprocarboxypeptidase Bprotaminasetissue carboxypeptidase B | |
| Modification date | 20180523 | 20180523 | |
| UniProtAcc | Q5JWF2 | P15086 | |
| Ensembl transtripts involved in fusion gene | ENST00000313949, ENST00000371098, ENST00000371075, ENST00000371100, ENST00000371099, ENST00000371102, ENST00000464624, ENST00000306120, ENST00000371095, ENST00000371085, ENST00000354359, ENST00000265620, ENST00000306090, ENST00000371081, | ENST00000491148, ENST00000282957, ENST00000498639, | |
| Fusion gene scores | * DoF score | 34 X 18 X 17=10404 | 21 X 24 X 3=1512 |
| # samples | 46 | 19 | |
| ** MAII score | log2(46/10404*10)=-4.49936063299862 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(19/1512*10)=-2.99238681589013 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: GNAS [Title/Abstract] AND CPB1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | BRCA | TCGA-A8-A091-01A | GNAS | chr20 | 57474040 | + | CPB1 | chr3 | 148545789 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 3UTR-3CDS | ENST00000313949 | ENST00000491148 | GNAS | chr20 | 57474040 | + | CPB1 | chr3 | 148545789 | + |
| 3UTR-3CDS | ENST00000313949 | ENST00000282957 | GNAS | chr20 | 57474040 | + | CPB1 | chr3 | 148545789 | + |
| 3UTR-intron | ENST00000313949 | ENST00000498639 | GNAS | chr20 | 57474040 | + | CPB1 | chr3 | 148545789 | + |
| 3UTR-3CDS | ENST00000371098 | ENST00000491148 | GNAS | chr20 | 57474040 | + | CPB1 | chr3 | 148545789 | + |
| 3UTR-3CDS | ENST00000371098 | ENST00000282957 | GNAS | chr20 | 57474040 | + | CPB1 | chr3 | 148545789 | + |
| 3UTR-intron | ENST00000371098 | ENST00000498639 | GNAS | chr20 | 57474040 | + | CPB1 | chr3 | 148545789 | + |
| 3UTR-3CDS | ENST00000371075 | ENST00000491148 | GNAS | chr20 | 57474040 | + | CPB1 | chr3 | 148545789 | + |
| 3UTR-3CDS | ENST00000371075 | ENST00000282957 | GNAS | chr20 | 57474040 | + | CPB1 | chr3 | 148545789 | + |
| 3UTR-intron | ENST00000371075 | ENST00000498639 | GNAS | chr20 | 57474040 | + | CPB1 | chr3 | 148545789 | + |
| In-frame | ENST00000371100 | ENST00000491148 | GNAS | chr20 | 57474040 | + | CPB1 | chr3 | 148545789 | + |
| In-frame | ENST00000371100 | ENST00000282957 | GNAS | chr20 | 57474040 | + | CPB1 | chr3 | 148545789 | + |
| 5CDS-intron | ENST00000371100 | ENST00000498639 | GNAS | chr20 | 57474040 | + | CPB1 | chr3 | 148545789 | + |
| intron-3CDS | ENST00000371099 | ENST00000491148 | GNAS | chr20 | 57474040 | + | CPB1 | chr3 | 148545789 | + |
| intron-3CDS | ENST00000371099 | ENST00000282957 | GNAS | chr20 | 57474040 | + | CPB1 | chr3 | 148545789 | + |
| intron-intron | ENST00000371099 | ENST00000498639 | GNAS | chr20 | 57474040 | + | CPB1 | chr3 | 148545789 | + |
| intron-3CDS | ENST00000371102 | ENST00000491148 | GNAS | chr20 | 57474040 | + | CPB1 | chr3 | 148545789 | + |
| intron-3CDS | ENST00000371102 | ENST00000282957 | GNAS | chr20 | 57474040 | + | CPB1 | chr3 | 148545789 | + |
| intron-intron | ENST00000371102 | ENST00000498639 | GNAS | chr20 | 57474040 | + | CPB1 | chr3 | 148545789 | + |
| 3UTR-3CDS | ENST00000464624 | ENST00000491148 | GNAS | chr20 | 57474040 | + | CPB1 | chr3 | 148545789 | + |
| 3UTR-3CDS | ENST00000464624 | ENST00000282957 | GNAS | chr20 | 57474040 | + | CPB1 | chr3 | 148545789 | + |
| 3UTR-intron | ENST00000464624 | ENST00000498639 | GNAS | chr20 | 57474040 | + | CPB1 | chr3 | 148545789 | + |
| intron-3CDS | ENST00000306120 | ENST00000491148 | GNAS | chr20 | 57474040 | + | CPB1 | chr3 | 148545789 | + |
| intron-3CDS | ENST00000306120 | ENST00000282957 | GNAS | chr20 | 57474040 | + | CPB1 | chr3 | 148545789 | + |
| intron-intron | ENST00000306120 | ENST00000498639 | GNAS | chr20 | 57474040 | + | CPB1 | chr3 | 148545789 | + |
| intron-3CDS | ENST00000371095 | ENST00000491148 | GNAS | chr20 | 57474040 | + | CPB1 | chr3 | 148545789 | + |
| intron-3CDS | ENST00000371095 | ENST00000282957 | GNAS | chr20 | 57474040 | + | CPB1 | chr3 | 148545789 | + |
| intron-intron | ENST00000371095 | ENST00000498639 | GNAS | chr20 | 57474040 | + | CPB1 | chr3 | 148545789 | + |
| In-frame | ENST00000371085 | ENST00000491148 | GNAS | chr20 | 57474040 | + | CPB1 | chr3 | 148545789 | + |
| In-frame | ENST00000371085 | ENST00000282957 | GNAS | chr20 | 57474040 | + | CPB1 | chr3 | 148545789 | + |
| 5CDS-intron | ENST00000371085 | ENST00000498639 | GNAS | chr20 | 57474040 | + | CPB1 | chr3 | 148545789 | + |
| In-frame | ENST00000354359 | ENST00000491148 | GNAS | chr20 | 57474040 | + | CPB1 | chr3 | 148545789 | + |
| In-frame | ENST00000354359 | ENST00000282957 | GNAS | chr20 | 57474040 | + | CPB1 | chr3 | 148545789 | + |
| 5CDS-intron | ENST00000354359 | ENST00000498639 | GNAS | chr20 | 57474040 | + | CPB1 | chr3 | 148545789 | + |
| intron-3CDS | ENST00000265620 | ENST00000491148 | GNAS | chr20 | 57474040 | + | CPB1 | chr3 | 148545789 | + |
| intron-3CDS | ENST00000265620 | ENST00000282957 | GNAS | chr20 | 57474040 | + | CPB1 | chr3 | 148545789 | + |
| intron-intron | ENST00000265620 | ENST00000498639 | GNAS | chr20 | 57474040 | + | CPB1 | chr3 | 148545789 | + |
| intron-3CDS | ENST00000306090 | ENST00000491148 | GNAS | chr20 | 57474040 | + | CPB1 | chr3 | 148545789 | + |
| intron-3CDS | ENST00000306090 | ENST00000282957 | GNAS | chr20 | 57474040 | + | CPB1 | chr3 | 148545789 | + |
| intron-intron | ENST00000306090 | ENST00000498639 | GNAS | chr20 | 57474040 | + | CPB1 | chr3 | 148545789 | + |
| In-frame | ENST00000371081 | ENST00000491148 | GNAS | chr20 | 57474040 | + | CPB1 | chr3 | 148545789 | + |
| In-frame | ENST00000371081 | ENST00000282957 | GNAS | chr20 | 57474040 | + | CPB1 | chr3 | 148545789 | + |
| 5CDS-intron | ENST00000371081 | ENST00000498639 | GNAS | chr20 | 57474040 | + | CPB1 | chr3 | 148545789 | + |
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FusionProtFeatures for GNAS_CPB1 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| GNAS | CPB1 |
| Guanine nucleotide-binding proteins (G proteins)function as transducers in numerous signaling pathways controlledby G protein-coupled receptors (GPCRs). Signaling involves theactivation of adenylyl cyclases, resulting in increased levels ofthe signaling molecule cAMP. GNAS functions downstream of severalGPCRs, including beta-adrenergic receptors. XLas isoforms interactwith the same set of receptors as GNAS isoforms (By similarity).{ECO:0000250|UniProtKB:Q6R0H7}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
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FusionGeneSequence for GNAS_CPB1 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_GNAS_ENST00000371100_chr20_57474040_+_CPB1_ENST00000491148_chr3_148545789_+_1123aa MGVRNCLYGNNMSGQRDIPPEIGEQPEQPPLEAPGAAAPGAGPSPAEEMETEPPHNEPIPVENDGEACGPPEVSRPNFQVLNPAFREAGA HGSYSPPPEEAMPFEAEQPSLGGFWPTLEQPGFPSGVHAGLEAFGPALMEPGAFSGARPGLGGYSPPPEEAMPFEFDQPAQRGCSQLLLQ VPDLAPGGPGAAGVPGAPPEEPQALRPAKAGSRGGYSPPPEETMPFELDGEGFGDDSPPPGLSRVIAQVDGSSQFAAVAASSAVRLTPAA NAPPLWVPGAIGSPSQEAVRPPSNFTGSSPWMEISGPPFEIGSAPAGVDDTPVNMDSPPIALDGPPIKVSGAPDKRERAERPPVEEEAAE MEGAADAAEGGKVPSPGYGSPAAGAASADTAARAAPAAPADPDSGATPEDPDSGTAPADPDSGAFAADPDSGAAPAAPADPDSGAAPDAP ADPDSGAAPDAPADPDAGAAPEAPAAPAAAETRAAHVAPAAPDAGAPTAPAASATRAAQVRRAASAAPASGARRKIHLRPPSPEIQAADP PTPRPTRASAWRGKSESSRGRRVYYDEGVASSDDDSSGDESDDGTSGCLRWFQHRRNRRRRKPQRNLLRNFLVQAFGGCFGRSESPQPKA SRSLKVKKVPLAEKRRQMRKEALEKRAQKRAEKKRSKLIDKQLQDEKMGYMCTHRLLLLGAGESGKSTIVKQMRILHVNGFNGEGGEEDP QAARSNSDGEKVFRVNVEDENHINIIRELASTTQIDFWKPDSVTQIKPHSTVDFRVKAEDTVTVENVLKQNELQYKVLISNLRNVVEAQF DSRVRATGHSYEKYNKWETIEAWTQQVATENPALISRSVIGTTFEGRAIYLLKVGKAGQNKPAIFMDCGFHAREWISPAFCQWFVREAVR TYGREIQVTELLDKLDFYVLPVLNIDGYIYTWTKSRFWRKTRSTHTGSSCIGTDPNRNFDAGWCEIGASRNPCDETYCGPAAESEKETKA LADFIRNKLSSIKAYLTIHSYSQMMIYPYSYAYKLGENNAELNALAKATVKELASLHGTKYTYGPGATTIYPAAGGSDDWAYDQGIRYSF >In-frame_GNAS_ENST00000371100_chr20_57474040_+_CPB1_ENST00000282957_chr3_148545789_+_1123aa MGVRNCLYGNNMSGQRDIPPEIGEQPEQPPLEAPGAAAPGAGPSPAEEMETEPPHNEPIPVENDGEACGPPEVSRPNFQVLNPAFREAGA HGSYSPPPEEAMPFEAEQPSLGGFWPTLEQPGFPSGVHAGLEAFGPALMEPGAFSGARPGLGGYSPPPEEAMPFEFDQPAQRGCSQLLLQ VPDLAPGGPGAAGVPGAPPEEPQALRPAKAGSRGGYSPPPEETMPFELDGEGFGDDSPPPGLSRVIAQVDGSSQFAAVAASSAVRLTPAA NAPPLWVPGAIGSPSQEAVRPPSNFTGSSPWMEISGPPFEIGSAPAGVDDTPVNMDSPPIALDGPPIKVSGAPDKRERAERPPVEEEAAE MEGAADAAEGGKVPSPGYGSPAAGAASADTAARAAPAAPADPDSGATPEDPDSGTAPADPDSGAFAADPDSGAAPAAPADPDSGAAPDAP ADPDSGAAPDAPADPDAGAAPEAPAAPAAAETRAAHVAPAAPDAGAPTAPAASATRAAQVRRAASAAPASGARRKIHLRPPSPEIQAADP PTPRPTRASAWRGKSESSRGRRVYYDEGVASSDDDSSGDESDDGTSGCLRWFQHRRNRRRRKPQRNLLRNFLVQAFGGCFGRSESPQPKA SRSLKVKKVPLAEKRRQMRKEALEKRAQKRAEKKRSKLIDKQLQDEKMGYMCTHRLLLLGAGESGKSTIVKQMRILHVNGFNGEGGEEDP QAARSNSDGEKVFRVNVEDENHINIIRELASTTQIDFWKPDSVTQIKPHSTVDFRVKAEDTVTVENVLKQNELQYKVLISNLRNVVEAQF DSRVRATGHSYEKYNKWETIEAWTQQVATENPALISRSVIGTTFEGRAIYLLKVGKAGQNKPAIFMDCGFHAREWISPAFCQWFVREAVR TYGREIQVTELLDKLDFYVLPVLNIDGYIYTWTKSRFWRKTRSTHTGSSCIGTDPNRNFDAGWCEIGASRNPCDETYCGPAAESEKETKA LADFIRNKLSSIKAYLTIHSYSQMMIYPYSYAYKLGENNAELNALAKATVKELASLHGTKYTYGPGATTIYPAAGGSDDWAYDQGIRYSF >In-frame_GNAS_ENST00000371085_chr20_57474040_+_CPB1_ENST00000491148_chr3_148545789_+_480aa MGCLGNSKTEDQRNEEKAQREANKKIEKQLQKDKQVYRATHRLLLLGAGESGKSTIVKQMRILHVNGFNGEGGEEDPQAARSNSDGEKVF RVNVEDENHINIIRELASTTQIDFWKPDSVTQIKPHSTVDFRVKAEDTVTVENVLKQNELQYKVLISNLRNVVEAQFDSRVRATGHSYEK YNKWETIEAWTQQVATENPALISRSVIGTTFEGRAIYLLKVGKAGQNKPAIFMDCGFHAREWISPAFCQWFVREAVRTYGREIQVTELLD KLDFYVLPVLNIDGYIYTWTKSRFWRKTRSTHTGSSCIGTDPNRNFDAGWCEIGASRNPCDETYCGPAAESEKETKALADFIRNKLSSIK AYLTIHSYSQMMIYPYSYAYKLGENNAELNALAKATVKELASLHGTKYTYGPGATTIYPAAGGSDDWAYDQGIRYSFTFELRDTGRYGFL >In-frame_GNAS_ENST00000371085_chr20_57474040_+_CPB1_ENST00000282957_chr3_148545789_+_480aa MGCLGNSKTEDQRNEEKAQREANKKIEKQLQKDKQVYRATHRLLLLGAGESGKSTIVKQMRILHVNGFNGEGGEEDPQAARSNSDGEKVF RVNVEDENHINIIRELASTTQIDFWKPDSVTQIKPHSTVDFRVKAEDTVTVENVLKQNELQYKVLISNLRNVVEAQFDSRVRATGHSYEK YNKWETIEAWTQQVATENPALISRSVIGTTFEGRAIYLLKVGKAGQNKPAIFMDCGFHAREWISPAFCQWFVREAVRTYGREIQVTELLD KLDFYVLPVLNIDGYIYTWTKSRFWRKTRSTHTGSSCIGTDPNRNFDAGWCEIGASRNPCDETYCGPAAESEKETKALADFIRNKLSSIK AYLTIHSYSQMMIYPYSYAYKLGENNAELNALAKATVKELASLHGTKYTYGPGATTIYPAAGGSDDWAYDQGIRYSFTFELRDTGRYGFL >In-frame_GNAS_ENST00000354359_chr20_57474040_+_CPB1_ENST00000491148_chr3_148545789_+_480aa MGCLGNSKTEDQRNEEKAQREANKKIEKQLQKDKQVYRATHRLLLLGAGESGKSTIVKQMRILHVNGFNGEGGEEDPQAARSNSDGEKVF RVNVEDENHINIIRELASTTQIDFWKPDSVTQIKPHSTVDFRVKAEDTVTVENVLKQNELQYKVLISNLRNVVEAQFDSRVRATGHSYEK YNKWETIEAWTQQVATENPALISRSVIGTTFEGRAIYLLKVGKAGQNKPAIFMDCGFHAREWISPAFCQWFVREAVRTYGREIQVTELLD KLDFYVLPVLNIDGYIYTWTKSRFWRKTRSTHTGSSCIGTDPNRNFDAGWCEIGASRNPCDETYCGPAAESEKETKALADFIRNKLSSIK AYLTIHSYSQMMIYPYSYAYKLGENNAELNALAKATVKELASLHGTKYTYGPGATTIYPAAGGSDDWAYDQGIRYSFTFELRDTGRYGFL >In-frame_GNAS_ENST00000354359_chr20_57474040_+_CPB1_ENST00000282957_chr3_148545789_+_480aa MGCLGNSKTEDQRNEEKAQREANKKIEKQLQKDKQVYRATHRLLLLGAGESGKSTIVKQMRILHVNGFNGEGGEEDPQAARSNSDGEKVF RVNVEDENHINIIRELASTTQIDFWKPDSVTQIKPHSTVDFRVKAEDTVTVENVLKQNELQYKVLISNLRNVVEAQFDSRVRATGHSYEK YNKWETIEAWTQQVATENPALISRSVIGTTFEGRAIYLLKVGKAGQNKPAIFMDCGFHAREWISPAFCQWFVREAVRTYGREIQVTELLD KLDFYVLPVLNIDGYIYTWTKSRFWRKTRSTHTGSSCIGTDPNRNFDAGWCEIGASRNPCDETYCGPAAESEKETKALADFIRNKLSSIK AYLTIHSYSQMMIYPYSYAYKLGENNAELNALAKATVKELASLHGTKYTYGPGATTIYPAAGGSDDWAYDQGIRYSFTFELRDTGRYGFL >In-frame_GNAS_ENST00000371081_chr20_57474040_+_CPB1_ENST00000491148_chr3_148545789_+_480aa MGCLGNSKTEDQRNEEKAQREANKKIEKQLQKDKQVYRATHRLLLLGAGESGKSTIVKQMRILHVNGFNGEGGEEDPQAARSNSDGEKVF RVNVEDENHINIIRELASTTQIDFWKPDSVTQIKPHSTVDFRVKAEDTVTVENVLKQNELQYKVLISNLRNVVEAQFDSRVRATGHSYEK YNKWETIEAWTQQVATENPALISRSVIGTTFEGRAIYLLKVGKAGQNKPAIFMDCGFHAREWISPAFCQWFVREAVRTYGREIQVTELLD KLDFYVLPVLNIDGYIYTWTKSRFWRKTRSTHTGSSCIGTDPNRNFDAGWCEIGASRNPCDETYCGPAAESEKETKALADFIRNKLSSIK AYLTIHSYSQMMIYPYSYAYKLGENNAELNALAKATVKELASLHGTKYTYGPGATTIYPAAGGSDDWAYDQGIRYSFTFELRDTGRYGFL >In-frame_GNAS_ENST00000371081_chr20_57474040_+_CPB1_ENST00000282957_chr3_148545789_+_480aa MGCLGNSKTEDQRNEEKAQREANKKIEKQLQKDKQVYRATHRLLLLGAGESGKSTIVKQMRILHVNGFNGEGGEEDPQAARSNSDGEKVF RVNVEDENHINIIRELASTTQIDFWKPDSVTQIKPHSTVDFRVKAEDTVTVENVLKQNELQYKVLISNLRNVVEAQFDSRVRATGHSYEK YNKWETIEAWTQQVATENPALISRSVIGTTFEGRAIYLLKVGKAGQNKPAIFMDCGFHAREWISPAFCQWFVREAVRTYGREIQVTELLD KLDFYVLPVLNIDGYIYTWTKSRFWRKTRSTHTGSSCIGTDPNRNFDAGWCEIGASRNPCDETYCGPAAESEKETKALADFIRNKLSSIK AYLTIHSYSQMMIYPYSYAYKLGENNAELNALAKATVKELASLHGTKYTYGPGATTIYPAAGGSDDWAYDQGIRYSFTFELRDTGRYGFL |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_GNAS_ENST00000371100_chr20_57474040_+_CPB1_ENST00000491148_chr3_148545789_+_3369nt ATGGGCGTGCGCAACTGCCTCTACGGCAATAATATGTCAGGACAACGCGATATCCCCCCTGAAATCGGGGAACAGCCCGAGCAACCACCT TTGGAGGCCCCAGGGGCAGCTGCCCCCGGTGCTGGGCCTAGCCCAGCCGAAGAGATGGAGACCGAACCGCCTCACAACGAGCCCATCCCC GTCGAGAATGATGGCGAGGCCTGTGGACCCCCAGAGGTCTCCAGACCCAACTTTCAGGTCCTCAACCCGGCATTCAGGGAAGCTGGAGCC CATGGAAGCTACAGCCCACCTCCTGAGGAAGCAATGCCCTTCGAGGCTGAACAGCCCAGCTTGGGAGGCTTCTGGCCTACACTGGAGCAG CCTGGATTCCCCAGTGGGGTCCATGCAGGCCTTGAGGCCTTCGGCCCAGCACTCATGGAGCCCGGAGCCTTCAGTGGTGCCAGACCAGGC CTGGGAGGATACAGCCCTCCACCAGAAGAAGCTATGCCCTTTGAGTTTGACCAGCCTGCCCAGAGAGGCTGCAGTCAACTTCTCTTACAG GTCCCAGACCTTGCTCCAGGAGGCCCAGGTGCTGCAGGGGTCCCCGGAGCTCCTCCCGAGGAGCCCCAAGCCCTCAGGCCTGCAAAGGCT GGCTCCAGAGGAGGCTACAGCCCTCCCCCTGAGGAGACTATGCCATTTGAGCTTGATGGAGAAGGATTTGGGGACGACAGCCCACCCCCG GGGCTTTCCCGAGTTATCGCACAAGTCGACGGCAGCAGCCAGTTCGCGGCAGTCGCGGCCTCGAGTGCGGTCCGCCTCACTCCCGCCGCG AACGCGCCTCCCCTCTGGGTCCCAGGCGCCATCGGCAGCCCATCCCAAGAGGCTGTCAGACCTCCTTCTAACTTCACGGGCAGCAGCCCC TGGATGGAGATCTCCGGACCCCCGTTCGAGATTGGCAGCGCCCCCGCTGGGGTCGACGACACTCCCGTCAACATGGACAGCCCCCCAATC GCGCTTGACGGCCCGCCCATCAAGGTCTCCGGAGCCCCAGATAAGAGAGAGCGAGCAGAGAGACCCCCAGTTGAGGAGGAAGCAGCAGAG ATGGAAGGAGCCGCTGATGCCGCGGAGGGAGGAAAAGTACCCTCTCCGGGGTACGGATCCCCTGCCGCCGGGGCAGCCTCAGCGGATACC GCTGCCAGGGCAGCCCCTGCAGCCCCAGCCGATCCTGACTCCGGGGCAACCCCAGAAGATCCCGACTCCGGGACAGCACCAGCCGATCCT GACTCCGGGGCATTCGCAGCCGATCCCGACTCCGGGGCAGCCCCTGCCGCCCCAGCCGATCCCGACTCCGGGGCGGCCCCTGACGCCCCA GCCGATCCCGACTCCGGGGCGGCCCCTGACGCCCCAGCCGATCCAGATGCCGGGGCGGCCCCTGAGGCTCCCGCCGCCCCTGCGGCTGCT GAGACCCGGGCAGCCCATGTCGCCCCAGCTGCGCCAGACGCAGGGGCTCCCACTGCCCCAGCCGCTTCTGCCACCCGGGCAGCCCAAGTC CGCCGGGCGGCCTCTGCAGCCCCTGCCTCCGGGGCCAGACGCAAGATCCATCTCAGACCCCCCAGCCCCGAGATCCAGGCTGCCGATCCG CCTACTCCGCGGCCTACTCGCGCGTCTGCCTGGCGGGGCAAGTCCGAGAGCAGCCGCGGCCGCCGCGTGTACTACGATGAAGGGGTGGCC AGCAGCGACGATGACTCCAGCGGAGACGAGTCCGACGATGGGACCTCCGGATGCCTCCGCTGGTTTCAGCATCGGCGAAATCGCCGCCGC CGAAAGCCCCAGCGCAACTTACTCCGCAACTTTCTCGTGCAAGCCTTCGGGGGCTGCTTCGGTCGATCTGAGAGTCCCCAGCCCAAAGCC TCGCGCTCTCTCAAGGTCAAGAAGGTACCCCTGGCGGAGAAGCGCAGACAGATGCGCAAAGAAGCCCTGGAGAAGCGGGCCCAGAAGCGC GCAGAGAAGAAACGCAGTAAGCTCATCGACAAACAACTCCAGGACGAAAAGATGGGCTACATGTGTACGCACCGCCTGCTGCTTCTAGGT GCTGGAGAATCTGGTAAAAGCACCATTGTGAAGCAGATGAGGATCCTGCATGTTAATGGGTTTAATGGAGAGGGCGGCGAAGAGGACCCG CAGGCTGCAAGGAGCAACAGCGATGGCGAGAAGGTGTTCCGTGTTAACGTTGAAGATGAAAATCACATTAACATAATCCGCGAGTTGGCC AGCACGACCCAGATTGACTTCTGGAAGCCAGATTCTGTCACACAAATCAAACCTCACAGTACAGTTGACTTCCGTGTTAAAGCAGAAGAT ACTGTCACTGTGGAGAATGTTCTAAAGCAGAATGAACTACAATACAAGGTACTGATAAGCAACCTGAGAAATGTGGTGGAGGCTCAGTTT GATAGCCGGGTTCGTGCAACAGGACACAGTTATGAGAAGTACAACAAGTGGGAAACGATAGAGGCTTGGACTCAACAAGTCGCCACTGAG AATCCAGCCCTCATCTCTCGCAGTGTTATCGGAACCACATTTGAGGGACGCGCTATTTACCTCCTGAAGGTTGGCAAAGCTGGACAAAAT AAGCCTGCCATTTTCATGGACTGTGGTTTCCATGCCAGAGAGTGGATTTCTCCTGCATTCTGCCAGTGGTTTGTAAGAGAGGCTGTTCGT ACCTATGGACGTGAGATCCAAGTGACAGAGCTTCTCGACAAGTTAGACTTTTATGTCCTGCCTGTGCTCAATATTGATGGCTACATCTAC ACCTGGACCAAGAGCCGATTTTGGAGAAAGACTCGCTCCACCCATACTGGATCTAGCTGCATTGGCACAGACCCCAACAGAAATTTTGAT GCTGGTTGGTGTGAAATTGGAGCCTCTCGAAACCCCTGTGATGAAACTTACTGTGGACCTGCCGCAGAGTCTGAAAAGGAGACCAAGGCC CTGGCTGATTTCATCCGCAACAAACTCTCTTCCATCAAGGCATATCTGACAATCCACTCGTACTCCCAAATGATGATCTACCCTTACTCA TATGCTTACAAACTCGGTGAGAACAATGCTGAGTTGAATGCCCTGGCTAAAGCTACTGTGAAAGAACTTGCCTCACTGCACGGCACCAAG TACACATATGGCCCGGGAGCTACAACAATCTATCCTGCTGCTGGGGGCTCTGACGACTGGGCTTATGACCAAGGAATCAGATATTCCTTC ACCTTTGAACTTCGAGATACAGGCAGATATGGCTTTCTCCTTCCAGAATCCCAGATCCGGGCTACCTGCGAGGAGACCTTCCTGGCAATC >In-frame_GNAS_ENST00000371100_chr20_57474040_+_CPB1_ENST00000282957_chr3_148545789_+_3369nt ATGGGCGTGCGCAACTGCCTCTACGGCAATAATATGTCAGGACAACGCGATATCCCCCCTGAAATCGGGGAACAGCCCGAGCAACCACCT TTGGAGGCCCCAGGGGCAGCTGCCCCCGGTGCTGGGCCTAGCCCAGCCGAAGAGATGGAGACCGAACCGCCTCACAACGAGCCCATCCCC GTCGAGAATGATGGCGAGGCCTGTGGACCCCCAGAGGTCTCCAGACCCAACTTTCAGGTCCTCAACCCGGCATTCAGGGAAGCTGGAGCC CATGGAAGCTACAGCCCACCTCCTGAGGAAGCAATGCCCTTCGAGGCTGAACAGCCCAGCTTGGGAGGCTTCTGGCCTACACTGGAGCAG CCTGGATTCCCCAGTGGGGTCCATGCAGGCCTTGAGGCCTTCGGCCCAGCACTCATGGAGCCCGGAGCCTTCAGTGGTGCCAGACCAGGC CTGGGAGGATACAGCCCTCCACCAGAAGAAGCTATGCCCTTTGAGTTTGACCAGCCTGCCCAGAGAGGCTGCAGTCAACTTCTCTTACAG GTCCCAGACCTTGCTCCAGGAGGCCCAGGTGCTGCAGGGGTCCCCGGAGCTCCTCCCGAGGAGCCCCAAGCCCTCAGGCCTGCAAAGGCT GGCTCCAGAGGAGGCTACAGCCCTCCCCCTGAGGAGACTATGCCATTTGAGCTTGATGGAGAAGGATTTGGGGACGACAGCCCACCCCCG GGGCTTTCCCGAGTTATCGCACAAGTCGACGGCAGCAGCCAGTTCGCGGCAGTCGCGGCCTCGAGTGCGGTCCGCCTCACTCCCGCCGCG AACGCGCCTCCCCTCTGGGTCCCAGGCGCCATCGGCAGCCCATCCCAAGAGGCTGTCAGACCTCCTTCTAACTTCACGGGCAGCAGCCCC TGGATGGAGATCTCCGGACCCCCGTTCGAGATTGGCAGCGCCCCCGCTGGGGTCGACGACACTCCCGTCAACATGGACAGCCCCCCAATC GCGCTTGACGGCCCGCCCATCAAGGTCTCCGGAGCCCCAGATAAGAGAGAGCGAGCAGAGAGACCCCCAGTTGAGGAGGAAGCAGCAGAG ATGGAAGGAGCCGCTGATGCCGCGGAGGGAGGAAAAGTACCCTCTCCGGGGTACGGATCCCCTGCCGCCGGGGCAGCCTCAGCGGATACC GCTGCCAGGGCAGCCCCTGCAGCCCCAGCCGATCCTGACTCCGGGGCAACCCCAGAAGATCCCGACTCCGGGACAGCACCAGCCGATCCT GACTCCGGGGCATTCGCAGCCGATCCCGACTCCGGGGCAGCCCCTGCCGCCCCAGCCGATCCCGACTCCGGGGCGGCCCCTGACGCCCCA GCCGATCCCGACTCCGGGGCGGCCCCTGACGCCCCAGCCGATCCAGATGCCGGGGCGGCCCCTGAGGCTCCCGCCGCCCCTGCGGCTGCT GAGACCCGGGCAGCCCATGTCGCCCCAGCTGCGCCAGACGCAGGGGCTCCCACTGCCCCAGCCGCTTCTGCCACCCGGGCAGCCCAAGTC CGCCGGGCGGCCTCTGCAGCCCCTGCCTCCGGGGCCAGACGCAAGATCCATCTCAGACCCCCCAGCCCCGAGATCCAGGCTGCCGATCCG CCTACTCCGCGGCCTACTCGCGCGTCTGCCTGGCGGGGCAAGTCCGAGAGCAGCCGCGGCCGCCGCGTGTACTACGATGAAGGGGTGGCC AGCAGCGACGATGACTCCAGCGGAGACGAGTCCGACGATGGGACCTCCGGATGCCTCCGCTGGTTTCAGCATCGGCGAAATCGCCGCCGC CGAAAGCCCCAGCGCAACTTACTCCGCAACTTTCTCGTGCAAGCCTTCGGGGGCTGCTTCGGTCGATCTGAGAGTCCCCAGCCCAAAGCC TCGCGCTCTCTCAAGGTCAAGAAGGTACCCCTGGCGGAGAAGCGCAGACAGATGCGCAAAGAAGCCCTGGAGAAGCGGGCCCAGAAGCGC GCAGAGAAGAAACGCAGTAAGCTCATCGACAAACAACTCCAGGACGAAAAGATGGGCTACATGTGTACGCACCGCCTGCTGCTTCTAGGT GCTGGAGAATCTGGTAAAAGCACCATTGTGAAGCAGATGAGGATCCTGCATGTTAATGGGTTTAATGGAGAGGGCGGCGAAGAGGACCCG CAGGCTGCAAGGAGCAACAGCGATGGCGAGAAGGTGTTCCGTGTTAACGTTGAAGATGAAAATCACATTAACATAATCCGCGAGTTGGCC AGCACGACCCAGATTGACTTCTGGAAGCCAGATTCTGTCACACAAATCAAACCTCACAGTACAGTTGACTTCCGTGTTAAAGCAGAAGAT ACTGTCACTGTGGAGAATGTTCTAAAGCAGAATGAACTACAATACAAGGTACTGATAAGCAACCTGAGAAATGTGGTGGAGGCTCAGTTT GATAGCCGGGTTCGTGCAACAGGACACAGTTATGAGAAGTACAACAAGTGGGAAACGATAGAGGCTTGGACTCAACAAGTCGCCACTGAG AATCCAGCCCTCATCTCTCGCAGTGTTATCGGAACCACATTTGAGGGACGCGCTATTTACCTCCTGAAGGTTGGCAAAGCTGGACAAAAT AAGCCTGCCATTTTCATGGACTGTGGTTTCCATGCCAGAGAGTGGATTTCTCCTGCATTCTGCCAGTGGTTTGTAAGAGAGGCTGTTCGT ACCTATGGACGTGAGATCCAAGTGACAGAGCTTCTCGACAAGTTAGACTTTTATGTCCTGCCTGTGCTCAATATTGATGGCTACATCTAC ACCTGGACCAAGAGCCGATTTTGGAGAAAGACTCGCTCCACCCATACTGGATCTAGCTGCATTGGCACAGACCCCAACAGAAATTTTGAT GCTGGTTGGTGTGAAATTGGAGCCTCTCGAAACCCCTGTGATGAAACTTACTGTGGACCTGCCGCAGAGTCTGAAAAGGAGACCAAGGCC CTGGCTGATTTCATCCGCAACAAACTCTCTTCCATCAAGGCATATCTGACAATCCACTCGTACTCCCAAATGATGATCTACCCTTACTCA TATGCTTACAAACTCGGTGAGAACAATGCTGAGTTGAATGCCCTGGCTAAAGCTACTGTGAAAGAACTTGCCTCACTGCACGGCACCAAG TACACATATGGCCCGGGAGCTACAACAATCTATCCTGCTGCTGGGGGCTCTGACGACTGGGCTTATGACCAAGGAATCAGATATTCCTTC ACCTTTGAACTTCGAGATACAGGCAGATATGGCTTTCTCCTTCCAGAATCCCAGATCCGGGCTACCTGCGAGGAGACCTTCCTGGCAATC >In-frame_GNAS_ENST00000371085_chr20_57474040_+_CPB1_ENST00000491148_chr3_148545789_+_1440nt ATGGGCTGCCTCGGGAACAGTAAGACCGAGGACCAGCGCAACGAGGAGAAGGCGCAGCGTGAGGCCAACAAAAAGATCGAGAAGCAGCTG CAGAAGGACAAGCAGGTCTACCGGGCCACGCACCGCCTGCTGCTGCTGGGTGCTGGAGAATCTGGTAAAAGCACCATTGTGAAGCAGATG AGGATCCTGCATGTTAATGGGTTTAATGGAGAGGGCGGCGAAGAGGACCCGCAGGCTGCAAGGAGCAACAGCGATGGCGAGAAGGTGTTC CGTGTTAACGTTGAAGATGAAAATCACATTAACATAATCCGCGAGTTGGCCAGCACGACCCAGATTGACTTCTGGAAGCCAGATTCTGTC ACACAAATCAAACCTCACAGTACAGTTGACTTCCGTGTTAAAGCAGAAGATACTGTCACTGTGGAGAATGTTCTAAAGCAGAATGAACTA CAATACAAGGTACTGATAAGCAACCTGAGAAATGTGGTGGAGGCTCAGTTTGATAGCCGGGTTCGTGCAACAGGACACAGTTATGAGAAG TACAACAAGTGGGAAACGATAGAGGCTTGGACTCAACAAGTCGCCACTGAGAATCCAGCCCTCATCTCTCGCAGTGTTATCGGAACCACA TTTGAGGGACGCGCTATTTACCTCCTGAAGGTTGGCAAAGCTGGACAAAATAAGCCTGCCATTTTCATGGACTGTGGTTTCCATGCCAGA GAGTGGATTTCTCCTGCATTCTGCCAGTGGTTTGTAAGAGAGGCTGTTCGTACCTATGGACGTGAGATCCAAGTGACAGAGCTTCTCGAC AAGTTAGACTTTTATGTCCTGCCTGTGCTCAATATTGATGGCTACATCTACACCTGGACCAAGAGCCGATTTTGGAGAAAGACTCGCTCC ACCCATACTGGATCTAGCTGCATTGGCACAGACCCCAACAGAAATTTTGATGCTGGTTGGTGTGAAATTGGAGCCTCTCGAAACCCCTGT GATGAAACTTACTGTGGACCTGCCGCAGAGTCTGAAAAGGAGACCAAGGCCCTGGCTGATTTCATCCGCAACAAACTCTCTTCCATCAAG GCATATCTGACAATCCACTCGTACTCCCAAATGATGATCTACCCTTACTCATATGCTTACAAACTCGGTGAGAACAATGCTGAGTTGAAT GCCCTGGCTAAAGCTACTGTGAAAGAACTTGCCTCACTGCACGGCACCAAGTACACATATGGCCCGGGAGCTACAACAATCTATCCTGCT GCTGGGGGCTCTGACGACTGGGCTTATGACCAAGGAATCAGATATTCCTTCACCTTTGAACTTCGAGATACAGGCAGATATGGCTTTCTC CTTCCAGAATCCCAGATCCGGGCTACCTGCGAGGAGACCTTCCTGGCAATCAAGTATGTTGCCAGCTACGTCCTGGAACACCTGTACTAG >In-frame_GNAS_ENST00000371085_chr20_57474040_+_CPB1_ENST00000282957_chr3_148545789_+_1440nt ATGGGCTGCCTCGGGAACAGTAAGACCGAGGACCAGCGCAACGAGGAGAAGGCGCAGCGTGAGGCCAACAAAAAGATCGAGAAGCAGCTG CAGAAGGACAAGCAGGTCTACCGGGCCACGCACCGCCTGCTGCTGCTGGGTGCTGGAGAATCTGGTAAAAGCACCATTGTGAAGCAGATG AGGATCCTGCATGTTAATGGGTTTAATGGAGAGGGCGGCGAAGAGGACCCGCAGGCTGCAAGGAGCAACAGCGATGGCGAGAAGGTGTTC CGTGTTAACGTTGAAGATGAAAATCACATTAACATAATCCGCGAGTTGGCCAGCACGACCCAGATTGACTTCTGGAAGCCAGATTCTGTC ACACAAATCAAACCTCACAGTACAGTTGACTTCCGTGTTAAAGCAGAAGATACTGTCACTGTGGAGAATGTTCTAAAGCAGAATGAACTA CAATACAAGGTACTGATAAGCAACCTGAGAAATGTGGTGGAGGCTCAGTTTGATAGCCGGGTTCGTGCAACAGGACACAGTTATGAGAAG TACAACAAGTGGGAAACGATAGAGGCTTGGACTCAACAAGTCGCCACTGAGAATCCAGCCCTCATCTCTCGCAGTGTTATCGGAACCACA TTTGAGGGACGCGCTATTTACCTCCTGAAGGTTGGCAAAGCTGGACAAAATAAGCCTGCCATTTTCATGGACTGTGGTTTCCATGCCAGA GAGTGGATTTCTCCTGCATTCTGCCAGTGGTTTGTAAGAGAGGCTGTTCGTACCTATGGACGTGAGATCCAAGTGACAGAGCTTCTCGAC AAGTTAGACTTTTATGTCCTGCCTGTGCTCAATATTGATGGCTACATCTACACCTGGACCAAGAGCCGATTTTGGAGAAAGACTCGCTCC ACCCATACTGGATCTAGCTGCATTGGCACAGACCCCAACAGAAATTTTGATGCTGGTTGGTGTGAAATTGGAGCCTCTCGAAACCCCTGT GATGAAACTTACTGTGGACCTGCCGCAGAGTCTGAAAAGGAGACCAAGGCCCTGGCTGATTTCATCCGCAACAAACTCTCTTCCATCAAG GCATATCTGACAATCCACTCGTACTCCCAAATGATGATCTACCCTTACTCATATGCTTACAAACTCGGTGAGAACAATGCTGAGTTGAAT GCCCTGGCTAAAGCTACTGTGAAAGAACTTGCCTCACTGCACGGCACCAAGTACACATATGGCCCGGGAGCTACAACAATCTATCCTGCT GCTGGGGGCTCTGACGACTGGGCTTATGACCAAGGAATCAGATATTCCTTCACCTTTGAACTTCGAGATACAGGCAGATATGGCTTTCTC CTTCCAGAATCCCAGATCCGGGCTACCTGCGAGGAGACCTTCCTGGCAATCAAGTATGTTGCCAGCTACGTCCTGGAACACCTGTACTAG >In-frame_GNAS_ENST00000354359_chr20_57474040_+_CPB1_ENST00000491148_chr3_148545789_+_1440nt ATGGGCTGCCTCGGGAACAGTAAGACCGAGGACCAGCGCAACGAGGAGAAGGCGCAGCGTGAGGCCAACAAAAAGATCGAGAAGCAGCTG CAGAAGGACAAGCAGGTCTACCGGGCCACGCACCGCCTGCTGCTGCTGGGTGCTGGAGAATCTGGTAAAAGCACCATTGTGAAGCAGATG AGGATCCTGCATGTTAATGGGTTTAATGGAGAGGGCGGCGAAGAGGACCCGCAGGCTGCAAGGAGCAACAGCGATGGCGAGAAGGTGTTC CGTGTTAACGTTGAAGATGAAAATCACATTAACATAATCCGCGAGTTGGCCAGCACGACCCAGATTGACTTCTGGAAGCCAGATTCTGTC ACACAAATCAAACCTCACAGTACAGTTGACTTCCGTGTTAAAGCAGAAGATACTGTCACTGTGGAGAATGTTCTAAAGCAGAATGAACTA CAATACAAGGTACTGATAAGCAACCTGAGAAATGTGGTGGAGGCTCAGTTTGATAGCCGGGTTCGTGCAACAGGACACAGTTATGAGAAG TACAACAAGTGGGAAACGATAGAGGCTTGGACTCAACAAGTCGCCACTGAGAATCCAGCCCTCATCTCTCGCAGTGTTATCGGAACCACA TTTGAGGGACGCGCTATTTACCTCCTGAAGGTTGGCAAAGCTGGACAAAATAAGCCTGCCATTTTCATGGACTGTGGTTTCCATGCCAGA GAGTGGATTTCTCCTGCATTCTGCCAGTGGTTTGTAAGAGAGGCTGTTCGTACCTATGGACGTGAGATCCAAGTGACAGAGCTTCTCGAC AAGTTAGACTTTTATGTCCTGCCTGTGCTCAATATTGATGGCTACATCTACACCTGGACCAAGAGCCGATTTTGGAGAAAGACTCGCTCC ACCCATACTGGATCTAGCTGCATTGGCACAGACCCCAACAGAAATTTTGATGCTGGTTGGTGTGAAATTGGAGCCTCTCGAAACCCCTGT GATGAAACTTACTGTGGACCTGCCGCAGAGTCTGAAAAGGAGACCAAGGCCCTGGCTGATTTCATCCGCAACAAACTCTCTTCCATCAAG GCATATCTGACAATCCACTCGTACTCCCAAATGATGATCTACCCTTACTCATATGCTTACAAACTCGGTGAGAACAATGCTGAGTTGAAT GCCCTGGCTAAAGCTACTGTGAAAGAACTTGCCTCACTGCACGGCACCAAGTACACATATGGCCCGGGAGCTACAACAATCTATCCTGCT GCTGGGGGCTCTGACGACTGGGCTTATGACCAAGGAATCAGATATTCCTTCACCTTTGAACTTCGAGATACAGGCAGATATGGCTTTCTC CTTCCAGAATCCCAGATCCGGGCTACCTGCGAGGAGACCTTCCTGGCAATCAAGTATGTTGCCAGCTACGTCCTGGAACACCTGTACTAG >In-frame_GNAS_ENST00000354359_chr20_57474040_+_CPB1_ENST00000282957_chr3_148545789_+_1440nt ATGGGCTGCCTCGGGAACAGTAAGACCGAGGACCAGCGCAACGAGGAGAAGGCGCAGCGTGAGGCCAACAAAAAGATCGAGAAGCAGCTG CAGAAGGACAAGCAGGTCTACCGGGCCACGCACCGCCTGCTGCTGCTGGGTGCTGGAGAATCTGGTAAAAGCACCATTGTGAAGCAGATG AGGATCCTGCATGTTAATGGGTTTAATGGAGAGGGCGGCGAAGAGGACCCGCAGGCTGCAAGGAGCAACAGCGATGGCGAGAAGGTGTTC CGTGTTAACGTTGAAGATGAAAATCACATTAACATAATCCGCGAGTTGGCCAGCACGACCCAGATTGACTTCTGGAAGCCAGATTCTGTC ACACAAATCAAACCTCACAGTACAGTTGACTTCCGTGTTAAAGCAGAAGATACTGTCACTGTGGAGAATGTTCTAAAGCAGAATGAACTA CAATACAAGGTACTGATAAGCAACCTGAGAAATGTGGTGGAGGCTCAGTTTGATAGCCGGGTTCGTGCAACAGGACACAGTTATGAGAAG TACAACAAGTGGGAAACGATAGAGGCTTGGACTCAACAAGTCGCCACTGAGAATCCAGCCCTCATCTCTCGCAGTGTTATCGGAACCACA TTTGAGGGACGCGCTATTTACCTCCTGAAGGTTGGCAAAGCTGGACAAAATAAGCCTGCCATTTTCATGGACTGTGGTTTCCATGCCAGA GAGTGGATTTCTCCTGCATTCTGCCAGTGGTTTGTAAGAGAGGCTGTTCGTACCTATGGACGTGAGATCCAAGTGACAGAGCTTCTCGAC AAGTTAGACTTTTATGTCCTGCCTGTGCTCAATATTGATGGCTACATCTACACCTGGACCAAGAGCCGATTTTGGAGAAAGACTCGCTCC ACCCATACTGGATCTAGCTGCATTGGCACAGACCCCAACAGAAATTTTGATGCTGGTTGGTGTGAAATTGGAGCCTCTCGAAACCCCTGT GATGAAACTTACTGTGGACCTGCCGCAGAGTCTGAAAAGGAGACCAAGGCCCTGGCTGATTTCATCCGCAACAAACTCTCTTCCATCAAG GCATATCTGACAATCCACTCGTACTCCCAAATGATGATCTACCCTTACTCATATGCTTACAAACTCGGTGAGAACAATGCTGAGTTGAAT GCCCTGGCTAAAGCTACTGTGAAAGAACTTGCCTCACTGCACGGCACCAAGTACACATATGGCCCGGGAGCTACAACAATCTATCCTGCT GCTGGGGGCTCTGACGACTGGGCTTATGACCAAGGAATCAGATATTCCTTCACCTTTGAACTTCGAGATACAGGCAGATATGGCTTTCTC CTTCCAGAATCCCAGATCCGGGCTACCTGCGAGGAGACCTTCCTGGCAATCAAGTATGTTGCCAGCTACGTCCTGGAACACCTGTACTAG >In-frame_GNAS_ENST00000371081_chr20_57474040_+_CPB1_ENST00000491148_chr3_148545789_+_1440nt ATGGGCTGCCTCGGGAACAGTAAGACCGAGGACCAGCGCAACGAGGAGAAGGCGCAGCGTGAGGCCAACAAAAAGATCGAGAAGCAGCTG CAGAAGGACAAGCAGGTCTACCGGGCCACGCACCGCCTGCTGCTGCTGGGTGCTGGAGAATCTGGTAAAAGCACCATTGTGAAGCAGATG AGGATCCTGCATGTTAATGGGTTTAATGGAGAGGGCGGCGAAGAGGACCCGCAGGCTGCAAGGAGCAACAGCGATGGCGAGAAGGTGTTC CGTGTTAACGTTGAAGATGAAAATCACATTAACATAATCCGCGAGTTGGCCAGCACGACCCAGATTGACTTCTGGAAGCCAGATTCTGTC ACACAAATCAAACCTCACAGTACAGTTGACTTCCGTGTTAAAGCAGAAGATACTGTCACTGTGGAGAATGTTCTAAAGCAGAATGAACTA CAATACAAGGTACTGATAAGCAACCTGAGAAATGTGGTGGAGGCTCAGTTTGATAGCCGGGTTCGTGCAACAGGACACAGTTATGAGAAG TACAACAAGTGGGAAACGATAGAGGCTTGGACTCAACAAGTCGCCACTGAGAATCCAGCCCTCATCTCTCGCAGTGTTATCGGAACCACA TTTGAGGGACGCGCTATTTACCTCCTGAAGGTTGGCAAAGCTGGACAAAATAAGCCTGCCATTTTCATGGACTGTGGTTTCCATGCCAGA GAGTGGATTTCTCCTGCATTCTGCCAGTGGTTTGTAAGAGAGGCTGTTCGTACCTATGGACGTGAGATCCAAGTGACAGAGCTTCTCGAC AAGTTAGACTTTTATGTCCTGCCTGTGCTCAATATTGATGGCTACATCTACACCTGGACCAAGAGCCGATTTTGGAGAAAGACTCGCTCC ACCCATACTGGATCTAGCTGCATTGGCACAGACCCCAACAGAAATTTTGATGCTGGTTGGTGTGAAATTGGAGCCTCTCGAAACCCCTGT GATGAAACTTACTGTGGACCTGCCGCAGAGTCTGAAAAGGAGACCAAGGCCCTGGCTGATTTCATCCGCAACAAACTCTCTTCCATCAAG GCATATCTGACAATCCACTCGTACTCCCAAATGATGATCTACCCTTACTCATATGCTTACAAACTCGGTGAGAACAATGCTGAGTTGAAT GCCCTGGCTAAAGCTACTGTGAAAGAACTTGCCTCACTGCACGGCACCAAGTACACATATGGCCCGGGAGCTACAACAATCTATCCTGCT GCTGGGGGCTCTGACGACTGGGCTTATGACCAAGGAATCAGATATTCCTTCACCTTTGAACTTCGAGATACAGGCAGATATGGCTTTCTC CTTCCAGAATCCCAGATCCGGGCTACCTGCGAGGAGACCTTCCTGGCAATCAAGTATGTTGCCAGCTACGTCCTGGAACACCTGTACTAG >In-frame_GNAS_ENST00000371081_chr20_57474040_+_CPB1_ENST00000282957_chr3_148545789_+_1440nt ATGGGCTGCCTCGGGAACAGTAAGACCGAGGACCAGCGCAACGAGGAGAAGGCGCAGCGTGAGGCCAACAAAAAGATCGAGAAGCAGCTG CAGAAGGACAAGCAGGTCTACCGGGCCACGCACCGCCTGCTGCTGCTGGGTGCTGGAGAATCTGGTAAAAGCACCATTGTGAAGCAGATG AGGATCCTGCATGTTAATGGGTTTAATGGAGAGGGCGGCGAAGAGGACCCGCAGGCTGCAAGGAGCAACAGCGATGGCGAGAAGGTGTTC CGTGTTAACGTTGAAGATGAAAATCACATTAACATAATCCGCGAGTTGGCCAGCACGACCCAGATTGACTTCTGGAAGCCAGATTCTGTC ACACAAATCAAACCTCACAGTACAGTTGACTTCCGTGTTAAAGCAGAAGATACTGTCACTGTGGAGAATGTTCTAAAGCAGAATGAACTA CAATACAAGGTACTGATAAGCAACCTGAGAAATGTGGTGGAGGCTCAGTTTGATAGCCGGGTTCGTGCAACAGGACACAGTTATGAGAAG TACAACAAGTGGGAAACGATAGAGGCTTGGACTCAACAAGTCGCCACTGAGAATCCAGCCCTCATCTCTCGCAGTGTTATCGGAACCACA TTTGAGGGACGCGCTATTTACCTCCTGAAGGTTGGCAAAGCTGGACAAAATAAGCCTGCCATTTTCATGGACTGTGGTTTCCATGCCAGA GAGTGGATTTCTCCTGCATTCTGCCAGTGGTTTGTAAGAGAGGCTGTTCGTACCTATGGACGTGAGATCCAAGTGACAGAGCTTCTCGAC AAGTTAGACTTTTATGTCCTGCCTGTGCTCAATATTGATGGCTACATCTACACCTGGACCAAGAGCCGATTTTGGAGAAAGACTCGCTCC ACCCATACTGGATCTAGCTGCATTGGCACAGACCCCAACAGAAATTTTGATGCTGGTTGGTGTGAAATTGGAGCCTCTCGAAACCCCTGT GATGAAACTTACTGTGGACCTGCCGCAGAGTCTGAAAAGGAGACCAAGGCCCTGGCTGATTTCATCCGCAACAAACTCTCTTCCATCAAG GCATATCTGACAATCCACTCGTACTCCCAAATGATGATCTACCCTTACTCATATGCTTACAAACTCGGTGAGAACAATGCTGAGTTGAAT GCCCTGGCTAAAGCTACTGTGAAAGAACTTGCCTCACTGCACGGCACCAAGTACACATATGGCCCGGGAGCTACAACAATCTATCCTGCT GCTGGGGGCTCTGACGACTGGGCTTATGACCAAGGAATCAGATATTCCTTCACCTTTGAACTTCGAGATACAGGCAGATATGGCTTTCTC CTTCCAGAATCCCAGATCCGGGCTACCTGCGAGGAGACCTTCCTGGCAATCAAGTATGTTGCCAGCTACGTCCTGGAACACCTGTACTAG |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_GNAS_ENST00000371100_chr20_57474040_+_CPB1_ENST00000491148_chr3_148545789_+_4106nt AAAGACTCCAAATCAGTCAGGGAGAGGAGTGGAAGGAGCCAAAACGTCCCTGCGAGGCCTGCGCTCACCAGCCCCCTTACCCAAAGTCCC GGGCCCCTGGCGCCAGGAGCAGGCTCCTGGAGCCGGAGCCAGCTCGGCACTGGAACCGGCGTCCTCTGGTGGCAGAGAGAGAGCGCTACT GGCGATTTTCGGACCGAATCGGCACGCTCGTCAGATCCAAGCAGGCGGGACTGGCCTGGAGCAAAAAGAAAGAGAGAGGAGGGCGTAAGG ATAGACCAAGGAAGAGGGGCTGGGGGGCAGCCTGGGGGCATGAAAAGTGGCCAGGAAGGAGCCAAGACTCCACCAGCAACAATTGAGTTG CTTCAGCCTCAGTCTAGGGTTCCTTCCAGGCCTTGAACCCCCCAACCTCACAAGGGTTGGAAAGTGAGGCCGGTGAACTTTCCAGCTGGT ACTTTGATTTTAAAATAATAATAATAATTTTTTCACCCTAGTTCGGTTGGGTGCTCCATCTTACGGAGCCCCAAACTTATTTTGAGAGGC CGCCACCGTGTTATGGGCGTGCGCAACTGCCTCTACGGCAATAATATGTCAGGACAACGCGATATCCCCCCTGAAATCGGGGAACAGCCC GAGCAACCACCTTTGGAGGCCCCAGGGGCAGCTGCCCCCGGTGCTGGGCCTAGCCCAGCCGAAGAGATGGAGACCGAACCGCCTCACAAC GAGCCCATCCCCGTCGAGAATGATGGCGAGGCCTGTGGACCCCCAGAGGTCTCCAGACCCAACTTTCAGGTCCTCAACCCGGCATTCAGG GAAGCTGGAGCCCATGGAAGCTACAGCCCACCTCCTGAGGAAGCAATGCCCTTCGAGGCTGAACAGCCCAGCTTGGGAGGCTTCTGGCCT ACACTGGAGCAGCCTGGATTCCCCAGTGGGGTCCATGCAGGCCTTGAGGCCTTCGGCCCAGCACTCATGGAGCCCGGAGCCTTCAGTGGT GCCAGACCAGGCCTGGGAGGATACAGCCCTCCACCAGAAGAAGCTATGCCCTTTGAGTTTGACCAGCCTGCCCAGAGAGGCTGCAGTCAA CTTCTCTTACAGGTCCCAGACCTTGCTCCAGGAGGCCCAGGTGCTGCAGGGGTCCCCGGAGCTCCTCCCGAGGAGCCCCAAGCCCTCAGG CCTGCAAAGGCTGGCTCCAGAGGAGGCTACAGCCCTCCCCCTGAGGAGACTATGCCATTTGAGCTTGATGGAGAAGGATTTGGGGACGAC AGCCCACCCCCGGGGCTTTCCCGAGTTATCGCACAAGTCGACGGCAGCAGCCAGTTCGCGGCAGTCGCGGCCTCGAGTGCGGTCCGCCTC ACTCCCGCCGCGAACGCGCCTCCCCTCTGGGTCCCAGGCGCCATCGGCAGCCCATCCCAAGAGGCTGTCAGACCTCCTTCTAACTTCACG GGCAGCAGCCCCTGGATGGAGATCTCCGGACCCCCGTTCGAGATTGGCAGCGCCCCCGCTGGGGTCGACGACACTCCCGTCAACATGGAC AGCCCCCCAATCGCGCTTGACGGCCCGCCCATCAAGGTCTCCGGAGCCCCAGATAAGAGAGAGCGAGCAGAGAGACCCCCAGTTGAGGAG GAAGCAGCAGAGATGGAAGGAGCCGCTGATGCCGCGGAGGGAGGAAAAGTACCCTCTCCGGGGTACGGATCCCCTGCCGCCGGGGCAGCC TCAGCGGATACCGCTGCCAGGGCAGCCCCTGCAGCCCCAGCCGATCCTGACTCCGGGGCAACCCCAGAAGATCCCGACTCCGGGACAGCA CCAGCCGATCCTGACTCCGGGGCATTCGCAGCCGATCCCGACTCCGGGGCAGCCCCTGCCGCCCCAGCCGATCCCGACTCCGGGGCGGCC CCTGACGCCCCAGCCGATCCCGACTCCGGGGCGGCCCCTGACGCCCCAGCCGATCCAGATGCCGGGGCGGCCCCTGAGGCTCCCGCCGCC CCTGCGGCTGCTGAGACCCGGGCAGCCCATGTCGCCCCAGCTGCGCCAGACGCAGGGGCTCCCACTGCCCCAGCCGCTTCTGCCACCCGG GCAGCCCAAGTCCGCCGGGCGGCCTCTGCAGCCCCTGCCTCCGGGGCCAGACGCAAGATCCATCTCAGACCCCCCAGCCCCGAGATCCAG GCTGCCGATCCGCCTACTCCGCGGCCTACTCGCGCGTCTGCCTGGCGGGGCAAGTCCGAGAGCAGCCGCGGCCGCCGCGTGTACTACGAT GAAGGGGTGGCCAGCAGCGACGATGACTCCAGCGGAGACGAGTCCGACGATGGGACCTCCGGATGCCTCCGCTGGTTTCAGCATCGGCGA AATCGCCGCCGCCGAAAGCCCCAGCGCAACTTACTCCGCAACTTTCTCGTGCAAGCCTTCGGGGGCTGCTTCGGTCGATCTGAGAGTCCC CAGCCCAAAGCCTCGCGCTCTCTCAAGGTCAAGAAGGTACCCCTGGCGGAGAAGCGCAGACAGATGCGCAAAGAAGCCCTGGAGAAGCGG GCCCAGAAGCGCGCAGAGAAGAAACGCAGTAAGCTCATCGACAAACAACTCCAGGACGAAAAGATGGGCTACATGTGTACGCACCGCCTG CTGCTTCTAGGTGCTGGAGAATCTGGTAAAAGCACCATTGTGAAGCAGATGAGGATCCTGCATGTTAATGGGTTTAATGGAGAGGGCGGC GAAGAGGACCCGCAGGCTGCAAGGAGCAACAGCGATGGCGAGAAGGTGTTCCGTGTTAACGTTGAAGATGAAAATCACATTAACATAATC CGCGAGTTGGCCAGCACGACCCAGATTGACTTCTGGAAGCCAGATTCTGTCACACAAATCAAACCTCACAGTACAGTTGACTTCCGTGTT AAAGCAGAAGATACTGTCACTGTGGAGAATGTTCTAAAGCAGAATGAACTACAATACAAGGTACTGATAAGCAACCTGAGAAATGTGGTG GAGGCTCAGTTTGATAGCCGGGTTCGTGCAACAGGACACAGTTATGAGAAGTACAACAAGTGGGAAACGATAGAGGCTTGGACTCAACAA GTCGCCACTGAGAATCCAGCCCTCATCTCTCGCAGTGTTATCGGAACCACATTTGAGGGACGCGCTATTTACCTCCTGAAGGTTGGCAAA GCTGGACAAAATAAGCCTGCCATTTTCATGGACTGTGGTTTCCATGCCAGAGAGTGGATTTCTCCTGCATTCTGCCAGTGGTTTGTAAGA GAGGCTGTTCGTACCTATGGACGTGAGATCCAAGTGACAGAGCTTCTCGACAAGTTAGACTTTTATGTCCTGCCTGTGCTCAATATTGAT GGCTACATCTACACCTGGACCAAGAGCCGATTTTGGAGAAAGACTCGCTCCACCCATACTGGATCTAGCTGCATTGGCACAGACCCCAAC AGAAATTTTGATGCTGGTTGGTGTGAAATTGGAGCCTCTCGAAACCCCTGTGATGAAACTTACTGTGGACCTGCCGCAGAGTCTGAAAAG GAGACCAAGGCCCTGGCTGATTTCATCCGCAACAAACTCTCTTCCATCAAGGCATATCTGACAATCCACTCGTACTCCCAAATGATGATC TACCCTTACTCATATGCTTACAAACTCGGTGAGAACAATGCTGAGTTGAATGCCCTGGCTAAAGCTACTGTGAAAGAACTTGCCTCACTG CACGGCACCAAGTACACATATGGCCCGGGAGCTACAACAATCTATCCTGCTGCTGGGGGCTCTGACGACTGGGCTTATGACCAAGGAATC AGATATTCCTTCACCTTTGAACTTCGAGATACAGGCAGATATGGCTTTCTCCTTCCAGAATCCCAGATCCGGGCTACCTGCGAGGAGACC TTCCTGGCAATCAAGTATGTTGCCAGCTACGTCCTGGAACACCTGTACTAGTTGAGAAAGCTGATGGCCTTGTTTCAAAATTCTCATTTT TCATTTCTTTTCTTTCTTGAATTCTTATTTTGGTTTGCCTGGATGTTTTGCAGATCCCAATCTTTCTTTTAAGCTTCTGGGTCTATTAAA >In-frame_GNAS_ENST00000371100_chr20_57474040_+_CPB1_ENST00000282957_chr3_148545789_+_4102nt AAAGACTCCAAATCAGTCAGGGAGAGGAGTGGAAGGAGCCAAAACGTCCCTGCGAGGCCTGCGCTCACCAGCCCCCTTACCCAAAGTCCC GGGCCCCTGGCGCCAGGAGCAGGCTCCTGGAGCCGGAGCCAGCTCGGCACTGGAACCGGCGTCCTCTGGTGGCAGAGAGAGAGCGCTACT GGCGATTTTCGGACCGAATCGGCACGCTCGTCAGATCCAAGCAGGCGGGACTGGCCTGGAGCAAAAAGAAAGAGAGAGGAGGGCGTAAGG ATAGACCAAGGAAGAGGGGCTGGGGGGCAGCCTGGGGGCATGAAAAGTGGCCAGGAAGGAGCCAAGACTCCACCAGCAACAATTGAGTTG CTTCAGCCTCAGTCTAGGGTTCCTTCCAGGCCTTGAACCCCCCAACCTCACAAGGGTTGGAAAGTGAGGCCGGTGAACTTTCCAGCTGGT ACTTTGATTTTAAAATAATAATAATAATTTTTTCACCCTAGTTCGGTTGGGTGCTCCATCTTACGGAGCCCCAAACTTATTTTGAGAGGC CGCCACCGTGTTATGGGCGTGCGCAACTGCCTCTACGGCAATAATATGTCAGGACAACGCGATATCCCCCCTGAAATCGGGGAACAGCCC GAGCAACCACCTTTGGAGGCCCCAGGGGCAGCTGCCCCCGGTGCTGGGCCTAGCCCAGCCGAAGAGATGGAGACCGAACCGCCTCACAAC GAGCCCATCCCCGTCGAGAATGATGGCGAGGCCTGTGGACCCCCAGAGGTCTCCAGACCCAACTTTCAGGTCCTCAACCCGGCATTCAGG GAAGCTGGAGCCCATGGAAGCTACAGCCCACCTCCTGAGGAAGCAATGCCCTTCGAGGCTGAACAGCCCAGCTTGGGAGGCTTCTGGCCT ACACTGGAGCAGCCTGGATTCCCCAGTGGGGTCCATGCAGGCCTTGAGGCCTTCGGCCCAGCACTCATGGAGCCCGGAGCCTTCAGTGGT GCCAGACCAGGCCTGGGAGGATACAGCCCTCCACCAGAAGAAGCTATGCCCTTTGAGTTTGACCAGCCTGCCCAGAGAGGCTGCAGTCAA CTTCTCTTACAGGTCCCAGACCTTGCTCCAGGAGGCCCAGGTGCTGCAGGGGTCCCCGGAGCTCCTCCCGAGGAGCCCCAAGCCCTCAGG CCTGCAAAGGCTGGCTCCAGAGGAGGCTACAGCCCTCCCCCTGAGGAGACTATGCCATTTGAGCTTGATGGAGAAGGATTTGGGGACGAC AGCCCACCCCCGGGGCTTTCCCGAGTTATCGCACAAGTCGACGGCAGCAGCCAGTTCGCGGCAGTCGCGGCCTCGAGTGCGGTCCGCCTC ACTCCCGCCGCGAACGCGCCTCCCCTCTGGGTCCCAGGCGCCATCGGCAGCCCATCCCAAGAGGCTGTCAGACCTCCTTCTAACTTCACG GGCAGCAGCCCCTGGATGGAGATCTCCGGACCCCCGTTCGAGATTGGCAGCGCCCCCGCTGGGGTCGACGACACTCCCGTCAACATGGAC AGCCCCCCAATCGCGCTTGACGGCCCGCCCATCAAGGTCTCCGGAGCCCCAGATAAGAGAGAGCGAGCAGAGAGACCCCCAGTTGAGGAG GAAGCAGCAGAGATGGAAGGAGCCGCTGATGCCGCGGAGGGAGGAAAAGTACCCTCTCCGGGGTACGGATCCCCTGCCGCCGGGGCAGCC TCAGCGGATACCGCTGCCAGGGCAGCCCCTGCAGCCCCAGCCGATCCTGACTCCGGGGCAACCCCAGAAGATCCCGACTCCGGGACAGCA CCAGCCGATCCTGACTCCGGGGCATTCGCAGCCGATCCCGACTCCGGGGCAGCCCCTGCCGCCCCAGCCGATCCCGACTCCGGGGCGGCC CCTGACGCCCCAGCCGATCCCGACTCCGGGGCGGCCCCTGACGCCCCAGCCGATCCAGATGCCGGGGCGGCCCCTGAGGCTCCCGCCGCC CCTGCGGCTGCTGAGACCCGGGCAGCCCATGTCGCCCCAGCTGCGCCAGACGCAGGGGCTCCCACTGCCCCAGCCGCTTCTGCCACCCGG GCAGCCCAAGTCCGCCGGGCGGCCTCTGCAGCCCCTGCCTCCGGGGCCAGACGCAAGATCCATCTCAGACCCCCCAGCCCCGAGATCCAG GCTGCCGATCCGCCTACTCCGCGGCCTACTCGCGCGTCTGCCTGGCGGGGCAAGTCCGAGAGCAGCCGCGGCCGCCGCGTGTACTACGAT GAAGGGGTGGCCAGCAGCGACGATGACTCCAGCGGAGACGAGTCCGACGATGGGACCTCCGGATGCCTCCGCTGGTTTCAGCATCGGCGA AATCGCCGCCGCCGAAAGCCCCAGCGCAACTTACTCCGCAACTTTCTCGTGCAAGCCTTCGGGGGCTGCTTCGGTCGATCTGAGAGTCCC CAGCCCAAAGCCTCGCGCTCTCTCAAGGTCAAGAAGGTACCCCTGGCGGAGAAGCGCAGACAGATGCGCAAAGAAGCCCTGGAGAAGCGG GCCCAGAAGCGCGCAGAGAAGAAACGCAGTAAGCTCATCGACAAACAACTCCAGGACGAAAAGATGGGCTACATGTGTACGCACCGCCTG CTGCTTCTAGGTGCTGGAGAATCTGGTAAAAGCACCATTGTGAAGCAGATGAGGATCCTGCATGTTAATGGGTTTAATGGAGAGGGCGGC GAAGAGGACCCGCAGGCTGCAAGGAGCAACAGCGATGGCGAGAAGGTGTTCCGTGTTAACGTTGAAGATGAAAATCACATTAACATAATC CGCGAGTTGGCCAGCACGACCCAGATTGACTTCTGGAAGCCAGATTCTGTCACACAAATCAAACCTCACAGTACAGTTGACTTCCGTGTT AAAGCAGAAGATACTGTCACTGTGGAGAATGTTCTAAAGCAGAATGAACTACAATACAAGGTACTGATAAGCAACCTGAGAAATGTGGTG GAGGCTCAGTTTGATAGCCGGGTTCGTGCAACAGGACACAGTTATGAGAAGTACAACAAGTGGGAAACGATAGAGGCTTGGACTCAACAA GTCGCCACTGAGAATCCAGCCCTCATCTCTCGCAGTGTTATCGGAACCACATTTGAGGGACGCGCTATTTACCTCCTGAAGGTTGGCAAA GCTGGACAAAATAAGCCTGCCATTTTCATGGACTGTGGTTTCCATGCCAGAGAGTGGATTTCTCCTGCATTCTGCCAGTGGTTTGTAAGA GAGGCTGTTCGTACCTATGGACGTGAGATCCAAGTGACAGAGCTTCTCGACAAGTTAGACTTTTATGTCCTGCCTGTGCTCAATATTGAT GGCTACATCTACACCTGGACCAAGAGCCGATTTTGGAGAAAGACTCGCTCCACCCATACTGGATCTAGCTGCATTGGCACAGACCCCAAC AGAAATTTTGATGCTGGTTGGTGTGAAATTGGAGCCTCTCGAAACCCCTGTGATGAAACTTACTGTGGACCTGCCGCAGAGTCTGAAAAG GAGACCAAGGCCCTGGCTGATTTCATCCGCAACAAACTCTCTTCCATCAAGGCATATCTGACAATCCACTCGTACTCCCAAATGATGATC TACCCTTACTCATATGCTTACAAACTCGGTGAGAACAATGCTGAGTTGAATGCCCTGGCTAAAGCTACTGTGAAAGAACTTGCCTCACTG CACGGCACCAAGTACACATATGGCCCGGGAGCTACAACAATCTATCCTGCTGCTGGGGGCTCTGACGACTGGGCTTATGACCAAGGAATC AGATATTCCTTCACCTTTGAACTTCGAGATACAGGCAGATATGGCTTTCTCCTTCCAGAATCCCAGATCCGGGCTACCTGCGAGGAGACC TTCCTGGCAATCAAGTATGTTGCCAGCTACGTCCTGGAACACCTGTACTAGTTGAGAAAGCTGATGGCCTTGTTTCAAAATTCTCATTTT TCATTTCTTTTCTTTCTTGAATTCTTATTTTGGTTTGCCTGGATGTTTTGCAGATCCCAATCTTTCTTTTAAGCTTCTGGGTCTATTAAA >In-frame_GNAS_ENST00000371085_chr20_57474040_+_CPB1_ENST00000491148_chr3_148545789_+_2049nt TCGCCGCCGCCGCCTCCTCCTCCCCCCGCCTCCCCCCGCCCGCCGCGGCGCTTTTGGCTCGGGGCGGCGGCGGGGGCCCGGCCGAGGCAA TAAGAGCGGCGGCGGCGGCAGCGGCGGCAGCAGCTCCCGCAGCTCCTGCTCTGGTCCGCCTCGGCCCGGCGGCGGCCATCAGCCCCCTCG GCCTCGGCTCGAGGGGCGGGGAGCTGCGCGCGCCCCTCGGTCCGACCGACACCCTCCCCTTCCCGCCCGTCCGCGCGCCCCGCGGCCCGC GGCCCGCAGTCCGCCCCGCGCGCTCCTTGCCGAGGAGCCGAGCCCGCGCCCGGCCCGCCCGCCCGGCGCTGCCCCGGCCCTCCCGGCCCG CGTGAGGCCGCCCGCGCCCGCCGCCGCCGCAGCCCGGCCGCGCCCCGCCGCCGCCGCCGCCGCCATGGGCTGCCTCGGGAACAGTAAGAC CGAGGACCAGCGCAACGAGGAGAAGGCGCAGCGTGAGGCCAACAAAAAGATCGAGAAGCAGCTGCAGAAGGACAAGCAGGTCTACCGGGC CACGCACCGCCTGCTGCTGCTGGGTGCTGGAGAATCTGGTAAAAGCACCATTGTGAAGCAGATGAGGATCCTGCATGTTAATGGGTTTAA TGGAGAGGGCGGCGAAGAGGACCCGCAGGCTGCAAGGAGCAACAGCGATGGCGAGAAGGTGTTCCGTGTTAACGTTGAAGATGAAAATCA CATTAACATAATCCGCGAGTTGGCCAGCACGACCCAGATTGACTTCTGGAAGCCAGATTCTGTCACACAAATCAAACCTCACAGTACAGT TGACTTCCGTGTTAAAGCAGAAGATACTGTCACTGTGGAGAATGTTCTAAAGCAGAATGAACTACAATACAAGGTACTGATAAGCAACCT GAGAAATGTGGTGGAGGCTCAGTTTGATAGCCGGGTTCGTGCAACAGGACACAGTTATGAGAAGTACAACAAGTGGGAAACGATAGAGGC TTGGACTCAACAAGTCGCCACTGAGAATCCAGCCCTCATCTCTCGCAGTGTTATCGGAACCACATTTGAGGGACGCGCTATTTACCTCCT GAAGGTTGGCAAAGCTGGACAAAATAAGCCTGCCATTTTCATGGACTGTGGTTTCCATGCCAGAGAGTGGATTTCTCCTGCATTCTGCCA GTGGTTTGTAAGAGAGGCTGTTCGTACCTATGGACGTGAGATCCAAGTGACAGAGCTTCTCGACAAGTTAGACTTTTATGTCCTGCCTGT GCTCAATATTGATGGCTACATCTACACCTGGACCAAGAGCCGATTTTGGAGAAAGACTCGCTCCACCCATACTGGATCTAGCTGCATTGG CACAGACCCCAACAGAAATTTTGATGCTGGTTGGTGTGAAATTGGAGCCTCTCGAAACCCCTGTGATGAAACTTACTGTGGACCTGCCGC AGAGTCTGAAAAGGAGACCAAGGCCCTGGCTGATTTCATCCGCAACAAACTCTCTTCCATCAAGGCATATCTGACAATCCACTCGTACTC CCAAATGATGATCTACCCTTACTCATATGCTTACAAACTCGGTGAGAACAATGCTGAGTTGAATGCCCTGGCTAAAGCTACTGTGAAAGA ACTTGCCTCACTGCACGGCACCAAGTACACATATGGCCCGGGAGCTACAACAATCTATCCTGCTGCTGGGGGCTCTGACGACTGGGCTTA TGACCAAGGAATCAGATATTCCTTCACCTTTGAACTTCGAGATACAGGCAGATATGGCTTTCTCCTTCCAGAATCCCAGATCCGGGCTAC CTGCGAGGAGACCTTCCTGGCAATCAAGTATGTTGCCAGCTACGTCCTGGAACACCTGTACTAGTTGAGAAAGCTGATGGCCTTGTTTCA AAATTCTCATTTTTCATTTCTTTTCTTTCTTGAATTCTTATTTTGGTTTGCCTGGATGTTTTGCAGATCCCAATCTTTCTTTTAAGCTTC >In-frame_GNAS_ENST00000371085_chr20_57474040_+_CPB1_ENST00000282957_chr3_148545789_+_2045nt TCGCCGCCGCCGCCTCCTCCTCCCCCCGCCTCCCCCCGCCCGCCGCGGCGCTTTTGGCTCGGGGCGGCGGCGGGGGCCCGGCCGAGGCAA TAAGAGCGGCGGCGGCGGCAGCGGCGGCAGCAGCTCCCGCAGCTCCTGCTCTGGTCCGCCTCGGCCCGGCGGCGGCCATCAGCCCCCTCG GCCTCGGCTCGAGGGGCGGGGAGCTGCGCGCGCCCCTCGGTCCGACCGACACCCTCCCCTTCCCGCCCGTCCGCGCGCCCCGCGGCCCGC GGCCCGCAGTCCGCCCCGCGCGCTCCTTGCCGAGGAGCCGAGCCCGCGCCCGGCCCGCCCGCCCGGCGCTGCCCCGGCCCTCCCGGCCCG CGTGAGGCCGCCCGCGCCCGCCGCCGCCGCAGCCCGGCCGCGCCCCGCCGCCGCCGCCGCCGCCATGGGCTGCCTCGGGAACAGTAAGAC CGAGGACCAGCGCAACGAGGAGAAGGCGCAGCGTGAGGCCAACAAAAAGATCGAGAAGCAGCTGCAGAAGGACAAGCAGGTCTACCGGGC CACGCACCGCCTGCTGCTGCTGGGTGCTGGAGAATCTGGTAAAAGCACCATTGTGAAGCAGATGAGGATCCTGCATGTTAATGGGTTTAA TGGAGAGGGCGGCGAAGAGGACCCGCAGGCTGCAAGGAGCAACAGCGATGGCGAGAAGGTGTTCCGTGTTAACGTTGAAGATGAAAATCA CATTAACATAATCCGCGAGTTGGCCAGCACGACCCAGATTGACTTCTGGAAGCCAGATTCTGTCACACAAATCAAACCTCACAGTACAGT TGACTTCCGTGTTAAAGCAGAAGATACTGTCACTGTGGAGAATGTTCTAAAGCAGAATGAACTACAATACAAGGTACTGATAAGCAACCT GAGAAATGTGGTGGAGGCTCAGTTTGATAGCCGGGTTCGTGCAACAGGACACAGTTATGAGAAGTACAACAAGTGGGAAACGATAGAGGC TTGGACTCAACAAGTCGCCACTGAGAATCCAGCCCTCATCTCTCGCAGTGTTATCGGAACCACATTTGAGGGACGCGCTATTTACCTCCT GAAGGTTGGCAAAGCTGGACAAAATAAGCCTGCCATTTTCATGGACTGTGGTTTCCATGCCAGAGAGTGGATTTCTCCTGCATTCTGCCA GTGGTTTGTAAGAGAGGCTGTTCGTACCTATGGACGTGAGATCCAAGTGACAGAGCTTCTCGACAAGTTAGACTTTTATGTCCTGCCTGT GCTCAATATTGATGGCTACATCTACACCTGGACCAAGAGCCGATTTTGGAGAAAGACTCGCTCCACCCATACTGGATCTAGCTGCATTGG CACAGACCCCAACAGAAATTTTGATGCTGGTTGGTGTGAAATTGGAGCCTCTCGAAACCCCTGTGATGAAACTTACTGTGGACCTGCCGC AGAGTCTGAAAAGGAGACCAAGGCCCTGGCTGATTTCATCCGCAACAAACTCTCTTCCATCAAGGCATATCTGACAATCCACTCGTACTC CCAAATGATGATCTACCCTTACTCATATGCTTACAAACTCGGTGAGAACAATGCTGAGTTGAATGCCCTGGCTAAAGCTACTGTGAAAGA ACTTGCCTCACTGCACGGCACCAAGTACACATATGGCCCGGGAGCTACAACAATCTATCCTGCTGCTGGGGGCTCTGACGACTGGGCTTA TGACCAAGGAATCAGATATTCCTTCACCTTTGAACTTCGAGATACAGGCAGATATGGCTTTCTCCTTCCAGAATCCCAGATCCGGGCTAC CTGCGAGGAGACCTTCCTGGCAATCAAGTATGTTGCCAGCTACGTCCTGGAACACCTGTACTAGTTGAGAAAGCTGATGGCCTTGTTTCA AAATTCTCATTTTTCATTTCTTTTCTTTCTTGAATTCTTATTTTGGTTTGCCTGGATGTTTTGCAGATCCCAATCTTTCTTTTAAGCTTC >In-frame_GNAS_ENST00000354359_chr20_57474040_+_CPB1_ENST00000491148_chr3_148545789_+_2049nt TCGCCGCCGCCGCCTCCTCCTCCCCCCGCCTCCCCCCGCCCGCCGCGGCGCTTTTGGCTCGGGGCGGCGGCGGGGGCCCGGCCGAGGCAA TAAGAGCGGCGGCGGCGGCAGCGGCGGCAGCAGCTCCCGCAGCTCCTGCTCTGGTCCGCCTCGGCCCGGCGGCGGCCATCAGCCCCCTCG GCCTCGGCTCGAGGGGCGGGGAGCTGCGCGCGCCCCTCGGTCCGACCGACACCCTCCCCTTCCCGCCCGTCCGCGCGCCCCGCGGCCCGC GGCCCGCAGTCCGCCCCGCGCGCTCCTTGCCGAGGAGCCGAGCCCGCGCCCGGCCCGCCCGCCCGGCGCTGCCCCGGCCCTCCCGGCCCG CGTGAGGCCGCCCGCGCCCGCCGCCGCCGCAGCCCGGCCGCGCCCCGCCGCCGCCGCCGCCGCCATGGGCTGCCTCGGGAACAGTAAGAC CGAGGACCAGCGCAACGAGGAGAAGGCGCAGCGTGAGGCCAACAAAAAGATCGAGAAGCAGCTGCAGAAGGACAAGCAGGTCTACCGGGC CACGCACCGCCTGCTGCTGCTGGGTGCTGGAGAATCTGGTAAAAGCACCATTGTGAAGCAGATGAGGATCCTGCATGTTAATGGGTTTAA TGGAGAGGGCGGCGAAGAGGACCCGCAGGCTGCAAGGAGCAACAGCGATGGCGAGAAGGTGTTCCGTGTTAACGTTGAAGATGAAAATCA CATTAACATAATCCGCGAGTTGGCCAGCACGACCCAGATTGACTTCTGGAAGCCAGATTCTGTCACACAAATCAAACCTCACAGTACAGT TGACTTCCGTGTTAAAGCAGAAGATACTGTCACTGTGGAGAATGTTCTAAAGCAGAATGAACTACAATACAAGGTACTGATAAGCAACCT GAGAAATGTGGTGGAGGCTCAGTTTGATAGCCGGGTTCGTGCAACAGGACACAGTTATGAGAAGTACAACAAGTGGGAAACGATAGAGGC TTGGACTCAACAAGTCGCCACTGAGAATCCAGCCCTCATCTCTCGCAGTGTTATCGGAACCACATTTGAGGGACGCGCTATTTACCTCCT GAAGGTTGGCAAAGCTGGACAAAATAAGCCTGCCATTTTCATGGACTGTGGTTTCCATGCCAGAGAGTGGATTTCTCCTGCATTCTGCCA GTGGTTTGTAAGAGAGGCTGTTCGTACCTATGGACGTGAGATCCAAGTGACAGAGCTTCTCGACAAGTTAGACTTTTATGTCCTGCCTGT GCTCAATATTGATGGCTACATCTACACCTGGACCAAGAGCCGATTTTGGAGAAAGACTCGCTCCACCCATACTGGATCTAGCTGCATTGG CACAGACCCCAACAGAAATTTTGATGCTGGTTGGTGTGAAATTGGAGCCTCTCGAAACCCCTGTGATGAAACTTACTGTGGACCTGCCGC AGAGTCTGAAAAGGAGACCAAGGCCCTGGCTGATTTCATCCGCAACAAACTCTCTTCCATCAAGGCATATCTGACAATCCACTCGTACTC CCAAATGATGATCTACCCTTACTCATATGCTTACAAACTCGGTGAGAACAATGCTGAGTTGAATGCCCTGGCTAAAGCTACTGTGAAAGA ACTTGCCTCACTGCACGGCACCAAGTACACATATGGCCCGGGAGCTACAACAATCTATCCTGCTGCTGGGGGCTCTGACGACTGGGCTTA TGACCAAGGAATCAGATATTCCTTCACCTTTGAACTTCGAGATACAGGCAGATATGGCTTTCTCCTTCCAGAATCCCAGATCCGGGCTAC CTGCGAGGAGACCTTCCTGGCAATCAAGTATGTTGCCAGCTACGTCCTGGAACACCTGTACTAGTTGAGAAAGCTGATGGCCTTGTTTCA AAATTCTCATTTTTCATTTCTTTTCTTTCTTGAATTCTTATTTTGGTTTGCCTGGATGTTTTGCAGATCCCAATCTTTCTTTTAAGCTTC >In-frame_GNAS_ENST00000354359_chr20_57474040_+_CPB1_ENST00000282957_chr3_148545789_+_2045nt TCGCCGCCGCCGCCTCCTCCTCCCCCCGCCTCCCCCCGCCCGCCGCGGCGCTTTTGGCTCGGGGCGGCGGCGGGGGCCCGGCCGAGGCAA TAAGAGCGGCGGCGGCGGCAGCGGCGGCAGCAGCTCCCGCAGCTCCTGCTCTGGTCCGCCTCGGCCCGGCGGCGGCCATCAGCCCCCTCG GCCTCGGCTCGAGGGGCGGGGAGCTGCGCGCGCCCCTCGGTCCGACCGACACCCTCCCCTTCCCGCCCGTCCGCGCGCCCCGCGGCCCGC GGCCCGCAGTCCGCCCCGCGCGCTCCTTGCCGAGGAGCCGAGCCCGCGCCCGGCCCGCCCGCCCGGCGCTGCCCCGGCCCTCCCGGCCCG CGTGAGGCCGCCCGCGCCCGCCGCCGCCGCAGCCCGGCCGCGCCCCGCCGCCGCCGCCGCCGCCATGGGCTGCCTCGGGAACAGTAAGAC CGAGGACCAGCGCAACGAGGAGAAGGCGCAGCGTGAGGCCAACAAAAAGATCGAGAAGCAGCTGCAGAAGGACAAGCAGGTCTACCGGGC CACGCACCGCCTGCTGCTGCTGGGTGCTGGAGAATCTGGTAAAAGCACCATTGTGAAGCAGATGAGGATCCTGCATGTTAATGGGTTTAA TGGAGAGGGCGGCGAAGAGGACCCGCAGGCTGCAAGGAGCAACAGCGATGGCGAGAAGGTGTTCCGTGTTAACGTTGAAGATGAAAATCA CATTAACATAATCCGCGAGTTGGCCAGCACGACCCAGATTGACTTCTGGAAGCCAGATTCTGTCACACAAATCAAACCTCACAGTACAGT TGACTTCCGTGTTAAAGCAGAAGATACTGTCACTGTGGAGAATGTTCTAAAGCAGAATGAACTACAATACAAGGTACTGATAAGCAACCT GAGAAATGTGGTGGAGGCTCAGTTTGATAGCCGGGTTCGTGCAACAGGACACAGTTATGAGAAGTACAACAAGTGGGAAACGATAGAGGC TTGGACTCAACAAGTCGCCACTGAGAATCCAGCCCTCATCTCTCGCAGTGTTATCGGAACCACATTTGAGGGACGCGCTATTTACCTCCT GAAGGTTGGCAAAGCTGGACAAAATAAGCCTGCCATTTTCATGGACTGTGGTTTCCATGCCAGAGAGTGGATTTCTCCTGCATTCTGCCA GTGGTTTGTAAGAGAGGCTGTTCGTACCTATGGACGTGAGATCCAAGTGACAGAGCTTCTCGACAAGTTAGACTTTTATGTCCTGCCTGT GCTCAATATTGATGGCTACATCTACACCTGGACCAAGAGCCGATTTTGGAGAAAGACTCGCTCCACCCATACTGGATCTAGCTGCATTGG CACAGACCCCAACAGAAATTTTGATGCTGGTTGGTGTGAAATTGGAGCCTCTCGAAACCCCTGTGATGAAACTTACTGTGGACCTGCCGC AGAGTCTGAAAAGGAGACCAAGGCCCTGGCTGATTTCATCCGCAACAAACTCTCTTCCATCAAGGCATATCTGACAATCCACTCGTACTC CCAAATGATGATCTACCCTTACTCATATGCTTACAAACTCGGTGAGAACAATGCTGAGTTGAATGCCCTGGCTAAAGCTACTGTGAAAGA ACTTGCCTCACTGCACGGCACCAAGTACACATATGGCCCGGGAGCTACAACAATCTATCCTGCTGCTGGGGGCTCTGACGACTGGGCTTA TGACCAAGGAATCAGATATTCCTTCACCTTTGAACTTCGAGATACAGGCAGATATGGCTTTCTCCTTCCAGAATCCCAGATCCGGGCTAC CTGCGAGGAGACCTTCCTGGCAATCAAGTATGTTGCCAGCTACGTCCTGGAACACCTGTACTAGTTGAGAAAGCTGATGGCCTTGTTTCA AAATTCTCATTTTTCATTTCTTTTCTTTCTTGAATTCTTATTTTGGTTTGCCTGGATGTTTTGCAGATCCCAATCTTTCTTTTAAGCTTC >In-frame_GNAS_ENST00000371081_chr20_57474040_+_CPB1_ENST00000491148_chr3_148545789_+_1636nt CCGCCGCCGCCATGGGCTGCCTCGGGAACAGTAAGACCGAGGACCAGCGCAACGAGGAGAAGGCGCAGCGTGAGGCCAACAAAAAGATCG AGAAGCAGCTGCAGAAGGACAAGCAGGTCTACCGGGCCACGCACCGCCTGCTGCTGCTGGGTGCTGGAGAATCTGGTAAAAGCACCATTG TGAAGCAGATGAGGATCCTGCATGTTAATGGGTTTAATGGAGAGGGCGGCGAAGAGGACCCGCAGGCTGCAAGGAGCAACAGCGATGGCG AGAAGGTGTTCCGTGTTAACGTTGAAGATGAAAATCACATTAACATAATCCGCGAGTTGGCCAGCACGACCCAGATTGACTTCTGGAAGC CAGATTCTGTCACACAAATCAAACCTCACAGTACAGTTGACTTCCGTGTTAAAGCAGAAGATACTGTCACTGTGGAGAATGTTCTAAAGC AGAATGAACTACAATACAAGGTACTGATAAGCAACCTGAGAAATGTGGTGGAGGCTCAGTTTGATAGCCGGGTTCGTGCAACAGGACACA GTTATGAGAAGTACAACAAGTGGGAAACGATAGAGGCTTGGACTCAACAAGTCGCCACTGAGAATCCAGCCCTCATCTCTCGCAGTGTTA TCGGAACCACATTTGAGGGACGCGCTATTTACCTCCTGAAGGTTGGCAAAGCTGGACAAAATAAGCCTGCCATTTTCATGGACTGTGGTT TCCATGCCAGAGAGTGGATTTCTCCTGCATTCTGCCAGTGGTTTGTAAGAGAGGCTGTTCGTACCTATGGACGTGAGATCCAAGTGACAG AGCTTCTCGACAAGTTAGACTTTTATGTCCTGCCTGTGCTCAATATTGATGGCTACATCTACACCTGGACCAAGAGCCGATTTTGGAGAA AGACTCGCTCCACCCATACTGGATCTAGCTGCATTGGCACAGACCCCAACAGAAATTTTGATGCTGGTTGGTGTGAAATTGGAGCCTCTC GAAACCCCTGTGATGAAACTTACTGTGGACCTGCCGCAGAGTCTGAAAAGGAGACCAAGGCCCTGGCTGATTTCATCCGCAACAAACTCT CTTCCATCAAGGCATATCTGACAATCCACTCGTACTCCCAAATGATGATCTACCCTTACTCATATGCTTACAAACTCGGTGAGAACAATG CTGAGTTGAATGCCCTGGCTAAAGCTACTGTGAAAGAACTTGCCTCACTGCACGGCACCAAGTACACATATGGCCCGGGAGCTACAACAA TCTATCCTGCTGCTGGGGGCTCTGACGACTGGGCTTATGACCAAGGAATCAGATATTCCTTCACCTTTGAACTTCGAGATACAGGCAGAT ATGGCTTTCTCCTTCCAGAATCCCAGATCCGGGCTACCTGCGAGGAGACCTTCCTGGCAATCAAGTATGTTGCCAGCTACGTCCTGGAAC ACCTGTACTAGTTGAGAAAGCTGATGGCCTTGTTTCAAAATTCTCATTTTTCATTTCTTTTCTTTCTTGAATTCTTATTTTGGTTTGCCT GGATGTTTTGCAGATCCCAATCTTTCTTTTAAGCTTCTGGGTCTATTAAACTAGGTAGATCTTTTCGTATTGATCATAATAAAAGTGAAT >In-frame_GNAS_ENST00000371081_chr20_57474040_+_CPB1_ENST00000282957_chr3_148545789_+_1632nt CCGCCGCCGCCATGGGCTGCCTCGGGAACAGTAAGACCGAGGACCAGCGCAACGAGGAGAAGGCGCAGCGTGAGGCCAACAAAAAGATCG AGAAGCAGCTGCAGAAGGACAAGCAGGTCTACCGGGCCACGCACCGCCTGCTGCTGCTGGGTGCTGGAGAATCTGGTAAAAGCACCATTG TGAAGCAGATGAGGATCCTGCATGTTAATGGGTTTAATGGAGAGGGCGGCGAAGAGGACCCGCAGGCTGCAAGGAGCAACAGCGATGGCG AGAAGGTGTTCCGTGTTAACGTTGAAGATGAAAATCACATTAACATAATCCGCGAGTTGGCCAGCACGACCCAGATTGACTTCTGGAAGC CAGATTCTGTCACACAAATCAAACCTCACAGTACAGTTGACTTCCGTGTTAAAGCAGAAGATACTGTCACTGTGGAGAATGTTCTAAAGC AGAATGAACTACAATACAAGGTACTGATAAGCAACCTGAGAAATGTGGTGGAGGCTCAGTTTGATAGCCGGGTTCGTGCAACAGGACACA GTTATGAGAAGTACAACAAGTGGGAAACGATAGAGGCTTGGACTCAACAAGTCGCCACTGAGAATCCAGCCCTCATCTCTCGCAGTGTTA TCGGAACCACATTTGAGGGACGCGCTATTTACCTCCTGAAGGTTGGCAAAGCTGGACAAAATAAGCCTGCCATTTTCATGGACTGTGGTT TCCATGCCAGAGAGTGGATTTCTCCTGCATTCTGCCAGTGGTTTGTAAGAGAGGCTGTTCGTACCTATGGACGTGAGATCCAAGTGACAG AGCTTCTCGACAAGTTAGACTTTTATGTCCTGCCTGTGCTCAATATTGATGGCTACATCTACACCTGGACCAAGAGCCGATTTTGGAGAA AGACTCGCTCCACCCATACTGGATCTAGCTGCATTGGCACAGACCCCAACAGAAATTTTGATGCTGGTTGGTGTGAAATTGGAGCCTCTC GAAACCCCTGTGATGAAACTTACTGTGGACCTGCCGCAGAGTCTGAAAAGGAGACCAAGGCCCTGGCTGATTTCATCCGCAACAAACTCT CTTCCATCAAGGCATATCTGACAATCCACTCGTACTCCCAAATGATGATCTACCCTTACTCATATGCTTACAAACTCGGTGAGAACAATG CTGAGTTGAATGCCCTGGCTAAAGCTACTGTGAAAGAACTTGCCTCACTGCACGGCACCAAGTACACATATGGCCCGGGAGCTACAACAA TCTATCCTGCTGCTGGGGGCTCTGACGACTGGGCTTATGACCAAGGAATCAGATATTCCTTCACCTTTGAACTTCGAGATACAGGCAGAT ATGGCTTTCTCCTTCCAGAATCCCAGATCCGGGCTACCTGCGAGGAGACCTTCCTGGCAATCAAGTATGTTGCCAGCTACGTCCTGGAAC ACCTGTACTAGTTGAGAAAGCTGATGGCCTTGTTTCAAAATTCTCATTTTTCATTTCTTTTCTTTCTTGAATTCTTATTTTGGTTTGCCT GGATGTTTTGCAGATCCCAATCTTTCTTTTAAGCTTCTGGGTCTATTAAACTAGGTAGATCTTTTCGTATTGATCATAATAAAAGTGAAT 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FusionGenePPI for GNAS_CPB1 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| GNAS | FSCN1, PAICS, RUVBL1, SHMT2, TTC1, ADCY6, CRHR1, RGS2, SNX13, VIPR1, GNAS, MDM2, CALM1, GNG2, PCK1, ADRB2, AVPR2, TBXA2R, GNB1, GNAQ, GNA11, SLC25A12, LAMTOR1, NUCB1, NUCB2, HLA-A, OPTN, PTGIR, FUS, AXIN1, PANX1, CCDC8, EGFR, JAK3, GNAL, GNG4, TRO, MAGED2, GNB2, GNB4, C1QBP, METAP2, CPT2, YBEY, GNG10, OCIAD1, GNA12, ARMCX3, GNG5, EIF4H, EML2, GIPC1, DIS3, PFAS, NTRK1, RIC8B, CHEK2, HERC2, XPO1, CAT, DBN1, FLNA, MYH9, DNAJC7, SYNPO, THOC2, ELMSAN1, ADCY2, CDC5L, CD47, GLP1R, NAP1L1, MTNR1B, TRIM25 | CPB1 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for GNAS_CPB1 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
| Tgene | CPB1 | P15086 | DB04272 | Citric Acid | Carboxypeptidase B | small molecule | approved|nutraceutical|vet_approved |
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RelatedDiseases for GNAS_CPB1 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | GNAS | C3494506 | Pseudohypoparathyroidism, Type Ia | 13 | CTD_human;ORPHANET;UNIPROT |
| Hgene | GNAS | C0242292 | McCune-Albright Syndrome | 5 | ORPHANET;UNIPROT |
| Hgene | GNAS | C2931404 | Albright's hereditary osteodystrophy | 4 | CTD_human |
| Hgene | GNAS | C0016065 | Polyostotic fibrous dysplasia | 3 | CTD_human;HPO;ORPHANET |
| Hgene | GNAS | C0033806 | Pseudohypoparathyroidism | 3 | CTD_human;HPO |
| Hgene | GNAS | C1857451 | Acth-Independent Macronodular Adrenal Hyperplasia | 3 | ORPHANET;UNIPROT |
| Hgene | GNAS | C0014130 | Endocrine System Diseases | 2 | CTD_human |
| Hgene | GNAS | C0034013 | Precocious Puberty | 2 | CTD_human;HPO |
| Hgene | GNAS | C0221263 | Cafe-au-Lait Spots | 2 | CTD_human |
| Hgene | GNAS | C0001206 | Acromegaly | 1 | CTD_human;HPO |
| Hgene | GNAS | C0001624 | Adrenal Gland Neoplasms | 1 | CTD_human |
| Hgene | GNAS | C0011573 | Endogenous depression | 1 | PSYGENET |
| Hgene | GNAS | C0019087 | Hemorrhagic Disorders | 1 | CTD_human |
| Hgene | GNAS | C0020538 | Hypertensive disease | 1 | CTD_human;HPO |
| Hgene | GNAS | C0021655 | Insulin Resistance | 1 | CTD_human |
| Hgene | GNAS | C0023897 | Liver Diseases, Parasitic | 1 | CTD_human |
| Hgene | GNAS | C0027819 | Neuroblastoma | 1 | CTD_human |
| Hgene | GNAS | C0028754 | Obesity | 1 | CTD_human;HPO |
| Hgene | GNAS | C0029396 | Heterotopic Ossification | 1 | CTD_human;HPO |
| Hgene | GNAS | C0032460 | Polycystic Ovary Syndrome | 1 | CTD_human |
| Hgene | GNAS | C0033835 | Pseudopseudohypoparathyroidism | 1 | CTD_human;ORPHANET |
| Hgene | GNAS | C0035204 | Respiration Disorders | 1 | CTD_human |
| Hgene | GNAS | C0036341 | Schizophrenia | 1 | PSYGENET |
| Hgene | GNAS | C0038587 | Substance Withdrawal Syndrome | 1 | CTD_human |
| Hgene | GNAS | C0039231 | Tachycardia | 1 | CTD_human |
| Hgene | GNAS | C0206698 | Cholangiocarcinoma | 1 | CTD_human |
| Hgene | GNAS | C0221357 | Brachydactyly | 1 | CTD_human;HPO |
| Hgene | GNAS | C0242184 | Hypoxia | 1 | CTD_human |
| Hgene | GNAS | C0242216 | Biliary calculi | 1 | CTD_human |
| Hgene | GNAS | C0334041 | Osteoma cutis | 1 | CTD_human;ORPHANET;UNIPROT |
| Hgene | GNAS | C0346302 | Growth Hormone-Secreting Pituitary Adenoma | 1 | CTD_human |
| Hgene | GNAS | C2932715 | Pseudohypoparathyroidism Type 1B | 1 | CTD_human;ORPHANET |
| Hgene | GNAS | C2932716 | Pseudohypoparathyroidism Type 1C | 1 | ORPHANET;UNIPROT |
| Hgene | GNAS | C3714756 | Intellectual Disability | 1 | CTD_human;HPO |
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