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Fusion gene ID: 14791 |
FusionGeneSummary for GMDS_EXOC2 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: GMDS_EXOC2 | Fusion gene ID: 14791 | Hgene | Tgene | Gene symbol | GMDS | EXOC2 | Gene ID | 2762 | 55770 |
| Gene name | GDP-mannose 4,6-dehydratase | exocyst complex component 2 | |
| Synonyms | GMD|SDR3E1 | SEC5|SEC5L1|Sec5p | |
| Cytomap | 6p25.3 | 6p25.3 | |
| Type of gene | protein-coding | protein-coding | |
| Description | GDP-mannose 4,6 dehydrataseGDP-D-mannose dehydrataseshort chain dehydrogenase/reductase family 3E, member 1 | exocyst complex component 2SEC5-like 1exocyst complex component Sec5 | |
| Modification date | 20180523 | 20180523 | |
| UniProtAcc | O60547 | Q96KP1 | |
| Ensembl transtripts involved in fusion gene | ENST00000530927, ENST00000380815, ENST00000467288, | ENST00000230449, ENST00000448181, ENST00000475028, | |
| Fusion gene scores | * DoF score | 17 X 9 X 11=1683 | 3 X 3 X 3=27 |
| # samples | 17 | 3 | |
| ** MAII score | log2(17/1683*10)=-3.30742852519225 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(3/27*10)=0.15200309344505 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
| Context | PubMed: GMDS [Title/Abstract] AND EXOC2 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | GMDS | GO:0019673 | GDP-mannose metabolic process | 9525924 |
| Hgene | GMDS | GO:0042351 | 'de novo' GDP-L-fucose biosynthetic process | 9525924 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | SARC | TCGA-DX-A8BU-01A | GMDS | chr6 | 1726650 | - | EXOC2 | chr6 | 556564 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000530927 | ENST00000230449 | GMDS | chr6 | 1726650 | - | EXOC2 | chr6 | 556564 | - |
| In-frame | ENST00000530927 | ENST00000448181 | GMDS | chr6 | 1726650 | - | EXOC2 | chr6 | 556564 | - |
| 5CDS-intron | ENST00000530927 | ENST00000475028 | GMDS | chr6 | 1726650 | - | EXOC2 | chr6 | 556564 | - |
| In-frame | ENST00000380815 | ENST00000230449 | GMDS | chr6 | 1726650 | - | EXOC2 | chr6 | 556564 | - |
| In-frame | ENST00000380815 | ENST00000448181 | GMDS | chr6 | 1726650 | - | EXOC2 | chr6 | 556564 | - |
| 5CDS-intron | ENST00000380815 | ENST00000475028 | GMDS | chr6 | 1726650 | - | EXOC2 | chr6 | 556564 | - |
| intron-3CDS | ENST00000467288 | ENST00000230449 | GMDS | chr6 | 1726650 | - | EXOC2 | chr6 | 556564 | - |
| intron-3CDS | ENST00000467288 | ENST00000448181 | GMDS | chr6 | 1726650 | - | EXOC2 | chr6 | 556564 | - |
| intron-intron | ENST00000467288 | ENST00000475028 | GMDS | chr6 | 1726650 | - | EXOC2 | chr6 | 556564 | - |
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FusionProtFeatures for GMDS_EXOC2 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| GMDS | EXOC2 |
| Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose. | Component of the exocyst complex involved in the dockingof exocytic vesicles with fusion sites on the plasma membrane. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | GMDS | chr6:1726650 | chr6:556564 | ENST00000380815 | - | 9 | 11 | 108_112 | 329 | 373 | Nucleotide binding | NADP |
| Hgene | GMDS | chr6:1726650 | chr6:556564 | ENST00000380815 | - | 9 | 11 | 30_35 | 329 | 373 | Nucleotide binding | NADP |
| Hgene | GMDS | chr6:1726650 | chr6:556564 | ENST00000380815 | - | 9 | 11 | 55_58 | 329 | 373 | Nucleotide binding | NADP |
| Hgene | GMDS | chr6:1726650 | chr6:556564 | ENST00000380815 | - | 9 | 11 | 86_87 | 329 | 373 | Nucleotide binding | NADP |
| Hgene | GMDS | chr6:1726650 | chr6:556564 | ENST00000530927 | - | 9 | 11 | 108_112 | 299 | 343 | Nucleotide binding | NADP |
| Hgene | GMDS | chr6:1726650 | chr6:556564 | ENST00000530927 | - | 9 | 11 | 30_35 | 299 | 343 | Nucleotide binding | NADP |
| Hgene | GMDS | chr6:1726650 | chr6:556564 | ENST00000530927 | - | 9 | 11 | 55_58 | 299 | 343 | Nucleotide binding | NADP |
| Hgene | GMDS | chr6:1726650 | chr6:556564 | ENST00000530927 | - | 9 | 11 | 86_87 | 299 | 343 | Nucleotide binding | NADP |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | EXOC2 | chr6:1726650 | chr6:556564 | ENST00000230449 | - | 16 | 28 | 240_260 | 617 | 925 | Coiled coil | Ontology_term=ECO:0000255 |
| Tgene | EXOC2 | chr6:1726650 | chr6:556564 | ENST00000230449 | - | 16 | 28 | 8_93 | 617 | 925 | Domain | Note=IPT/TIG |
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FusionGeneSequence for GMDS_EXOC2 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_GMDS_ENST00000530927_chr6_1726650_-_EXOC2_ENST00000230449_chr6_556564_-_607aa MCKMDGSYLAEFLLEKGYEVHGIVRRSSSFNTGRIEHLYKNPQAHIEGNMKLHYGDLTDSTCLVKIINEVKPTEIYNLGAQSHVKISFDL AEYTADVDGVGTLRLLDAVKTCGLINSVKFYQASTSELYGKVQEIPQKETTPFYPRSPYGAAKLYAYWIVVNFREAYNLFAVNGILFNHE SPRRGANFVTRKISRSVAKIYLGQLECFSLGNLDAKRDWGHAKDYVEAMWLMLQNDEPEDFVIATGEVHSVREFVEKSFLHIGKTIVWEG KNENEVGRCKETGKVHVTVDLKYYRPTEVPCQFEQCIVCSLQSLKGVLECKPGEASVFQQPKTQEEVCQLSINIMQVFIYCLEQLSTKPD ADIDTTHLSVDVSSPDLFGSIHEDFSLTSEQRLLIVLSNCCYLERHTFLNIAEHFEKHNFQGIEKITQVSMASLKELDQRLFENYIELKA DPIVGSLEPGIYAGYFDWKDCLPPTGVRNYLKEALVNIIAVHAEVFTISKELVPRVLSKVIEAVSEELSRLMQCVSSFSKNGALQARLEI >In-frame_GMDS_ENST00000530927_chr6_1726650_-_EXOC2_ENST00000448181_chr6_556564_-_607aa MCKMDGSYLAEFLLEKGYEVHGIVRRSSSFNTGRIEHLYKNPQAHIEGNMKLHYGDLTDSTCLVKIINEVKPTEIYNLGAQSHVKISFDL AEYTADVDGVGTLRLLDAVKTCGLINSVKFYQASTSELYGKVQEIPQKETTPFYPRSPYGAAKLYAYWIVVNFREAYNLFAVNGILFNHE SPRRGANFVTRKISRSVAKIYLGQLECFSLGNLDAKRDWGHAKDYVEAMWLMLQNDEPEDFVIATGEVHSVREFVEKSFLHIGKTIVWEG KNENEVGRCKETGKVHVTVDLKYYRPTEVPCQFEQCIVCSLQSLKGVLECKPGEASVFQQPKTQEEVCQLSINIMQVFIYCLEQLSTKPD ADIDTTHLSVDVSSPDLFGSIHEDFSLTSEQRLLIVLSNCCYLERHTFLNIAEHFEKHNFQGIEKITQVSMASLKELDQRLFENYIELKA DPIVGSLEPGIYAGYFDWKDCLPPTGVRNYLKEALVNIIAVHAEVFTISKELVPRVLSKVIEAVSEELSRLMQCVSSFSKNGALQARLEI >In-frame_GMDS_ENST00000380815_chr6_1726650_-_EXOC2_ENST00000230449_chr6_556564_-_637aa MAHAPARCPSARGSGDGEMGKPRNVALITGITGQDGSYLAEFLLEKGYEVHGIVRRSSSFNTGRIEHLYKNPQAHIEGNMKLHYGDLTDS TCLVKIINEVKPTEIYNLGAQSHVKISFDLAEYTADVDGVGTLRLLDAVKTCGLINSVKFYQASTSELYGKVQEIPQKETTPFYPRSPYG AAKLYAYWIVVNFREAYNLFAVNGILFNHESPRRGANFVTRKISRSVAKIYLGQLECFSLGNLDAKRDWGHAKDYVEAMWLMLQNDEPED FVIATGEVHSVREFVEKSFLHIGKTIVWEGKNENEVGRCKETGKVHVTVDLKYYRPTEVPCQFEQCIVCSLQSLKGVLECKPGEASVFQQ PKTQEEVCQLSINIMQVFIYCLEQLSTKPDADIDTTHLSVDVSSPDLFGSIHEDFSLTSEQRLLIVLSNCCYLERHTFLNIAEHFEKHNF QGIEKITQVSMASLKELDQRLFENYIELKADPIVGSLEPGIYAGYFDWKDCLPPTGVRNYLKEALVNIIAVHAEVFTISKELVPRVLSKV IEAVSEELSRLMQCVSSFSKNGALQARLEICALRDTVAVYLTPESKSSFKQALEALPQLSSGADKKLLEELLNKFKSSMHLQLTCFQAAS >In-frame_GMDS_ENST00000380815_chr6_1726650_-_EXOC2_ENST00000448181_chr6_556564_-_637aa MAHAPARCPSARGSGDGEMGKPRNVALITGITGQDGSYLAEFLLEKGYEVHGIVRRSSSFNTGRIEHLYKNPQAHIEGNMKLHYGDLTDS TCLVKIINEVKPTEIYNLGAQSHVKISFDLAEYTADVDGVGTLRLLDAVKTCGLINSVKFYQASTSELYGKVQEIPQKETTPFYPRSPYG AAKLYAYWIVVNFREAYNLFAVNGILFNHESPRRGANFVTRKISRSVAKIYLGQLECFSLGNLDAKRDWGHAKDYVEAMWLMLQNDEPED FVIATGEVHSVREFVEKSFLHIGKTIVWEGKNENEVGRCKETGKVHVTVDLKYYRPTEVPCQFEQCIVCSLQSLKGVLECKPGEASVFQQ PKTQEEVCQLSINIMQVFIYCLEQLSTKPDADIDTTHLSVDVSSPDLFGSIHEDFSLTSEQRLLIVLSNCCYLERHTFLNIAEHFEKHNF QGIEKITQVSMASLKELDQRLFENYIELKADPIVGSLEPGIYAGYFDWKDCLPPTGVRNYLKEALVNIIAVHAEVFTISKELVPRVLSKV IEAVSEELSRLMQCVSSFSKNGALQARLEICALRDTVAVYLTPESKSSFKQALEALPQLSSGADKKLLEELLNKFKSSMHLQLTCFQAAS |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_GMDS_ENST00000530927_chr6_1726650_-_EXOC2_ENST00000230449_chr6_556564_-_1821nt ATGTGTAAAATGGATGGTTCCTACCTGGCTGAGTTCCTGCTGGAGAAAGGCTATGAGGTCCATGGAATTGTACGGCGGTCCAGTTCATTT AATACGGGTCGAATTGAGCATCTGTATAAGAATCCCCAGGCTCACATTGAAGGAAACATGAAGTTGCACTATGGCGATCTCACTGACAGT ACCTGCCTTGTGAAGATCATTAATGAAGTAAAGCCCACAGAGATCTACAACCTTGGAGCCCAGAGCCACGTCAAAATTTCCTTTGACCTC GCTGAGTACACTGCGGACGTTGACGGAGTTGGCACTCTACGACTTCTAGATGCAGTTAAGACTTGTGGCCTTATCAACTCTGTGAAGTTC TACCAAGCCTCAACAAGTGAACTTTATGGGAAAGTGCAGGAAATACCCCAGAAGGAGACCACCCCTTTCTATCCCCGGTCACCCTATGGG GCAGCAAAACTCTATGCCTATTGGATTGTGGTGAACTTCCGTGAGGCGTATAATCTCTTTGCAGTGAACGGCATTCTCTTCAATCATGAG AGTCCCAGAAGAGGAGCTAATTTCGTTACTCGAAAAATTAGCCGGTCAGTAGCTAAGATTTACCTTGGACAACTGGAATGTTTCAGTTTG GGAAATCTGGATGCCAAACGAGATTGGGGCCATGCCAAGGACTATGTGGAGGCTATGTGGTTGATGTTGCAGAATGATGAGCCGGAGGAC TTCGTTATAGCTACTGGGGAGGTCCATAGTGTCCGGGAATTTGTCGAGAAATCATTCTTGCACATTGGAAAAACCATTGTGTGGGAAGGA AAGAATGAAAATGAAGTGGGCAGATGTAAAGAGACCGGCAAAGTTCACGTGACTGTGGATCTCAAGTACTACCGGCCAACTGAAGTGCCA TGTCAGTTTGAACAGTGCATCGTGTGTTCTCTGCAGTCACTGAAGGGGGTTCTGGAGTGCAAGCCGGGAGAGGCCAGTGTCTTCCAACAA CCTAAAACACAGGAGGAGGTTTGCCAGCTAAGCATCAATATAATGCAGGTTTTTATATACTGTCTGGAACAGTTGAGCACCAAGCCTGAT GCAGATATAGATACTACACATCTCTCTGTTGATGTTTCTTCCCCTGACTTGTTTGGAAGTATCCATGAAGACTTCAGCTTGACCTCAGAA CAGCGCCTTTTGATAGTCCTAAGTAATTGCTGCTATCTAGAACGTCACACCTTCCTAAATATCGCAGAACATTTTGAAAAGCACAACTTC CAGGGAATAGAAAAAATCACACAGGTTAGCATGGCCTCATTGAAAGAACTAGATCAAAGACTCTTTGAAAATTACATCGAGTTGAAAGCA GATCCCATCGTTGGCTCCTTAGAACCTGGAATTTATGCAGGATATTTTGATTGGAAGGACTGCCTGCCTCCAACAGGTGTCAGAAACTAT TTAAAAGAAGCACTGGTGAATATAATTGCCGTGCATGCAGAGGTGTTCACCATTTCCAAAGAACTGGTCCCTCGGGTACTATCCAAGGTG ATAGAAGCAGTTTCTGAAGAGCTCAGTCGACTGATGCAGTGTGTTTCATCCTTCAGCAAAAATGGAGCTTTACAGGCGAGACTTGAAATC TGTGCTTTGAGGGACACTGTGGCTGTTTACCTGACACCCGAAAGCAAGTCAAGTTTTAAGCAGGCTTTGGAAGCCCTGCCCCAGCTTTCC AGTGGAGCAGATAAAAAGTTACTGGAAGAGCTCCTGAACAAGTTCAAGAGTAGCATGCACTTGCAGCTCACCTGTTTCCAAGCAGCTTCT >In-frame_GMDS_ENST00000530927_chr6_1726650_-_EXOC2_ENST00000448181_chr6_556564_-_1821nt ATGTGTAAAATGGATGGTTCCTACCTGGCTGAGTTCCTGCTGGAGAAAGGCTATGAGGTCCATGGAATTGTACGGCGGTCCAGTTCATTT AATACGGGTCGAATTGAGCATCTGTATAAGAATCCCCAGGCTCACATTGAAGGAAACATGAAGTTGCACTATGGCGATCTCACTGACAGT ACCTGCCTTGTGAAGATCATTAATGAAGTAAAGCCCACAGAGATCTACAACCTTGGAGCCCAGAGCCACGTCAAAATTTCCTTTGACCTC GCTGAGTACACTGCGGACGTTGACGGAGTTGGCACTCTACGACTTCTAGATGCAGTTAAGACTTGTGGCCTTATCAACTCTGTGAAGTTC TACCAAGCCTCAACAAGTGAACTTTATGGGAAAGTGCAGGAAATACCCCAGAAGGAGACCACCCCTTTCTATCCCCGGTCACCCTATGGG GCAGCAAAACTCTATGCCTATTGGATTGTGGTGAACTTCCGTGAGGCGTATAATCTCTTTGCAGTGAACGGCATTCTCTTCAATCATGAG AGTCCCAGAAGAGGAGCTAATTTCGTTACTCGAAAAATTAGCCGGTCAGTAGCTAAGATTTACCTTGGACAACTGGAATGTTTCAGTTTG GGAAATCTGGATGCCAAACGAGATTGGGGCCATGCCAAGGACTATGTGGAGGCTATGTGGTTGATGTTGCAGAATGATGAGCCGGAGGAC TTCGTTATAGCTACTGGGGAGGTCCATAGTGTCCGGGAATTTGTCGAGAAATCATTCTTGCACATTGGAAAAACCATTGTGTGGGAAGGA AAGAATGAAAATGAAGTGGGCAGATGTAAAGAGACCGGCAAAGTTCACGTGACTGTGGATCTCAAGTACTACCGGCCAACTGAAGTGCCA TGTCAGTTTGAACAGTGCATCGTGTGTTCTCTGCAGTCACTGAAGGGGGTTCTGGAGTGCAAGCCGGGAGAGGCCAGTGTCTTCCAACAA CCTAAAACACAGGAGGAGGTTTGCCAGCTAAGCATCAATATAATGCAGGTTTTTATATACTGTCTGGAACAGTTGAGCACCAAGCCTGAT GCAGATATAGATACTACACATCTCTCTGTTGATGTTTCTTCCCCTGACTTGTTTGGAAGTATCCATGAAGACTTCAGCTTGACCTCAGAA CAGCGCCTTTTGATAGTCCTAAGTAATTGCTGCTATCTAGAACGTCACACCTTCCTAAATATCGCAGAACATTTTGAAAAGCACAACTTC CAGGGAATAGAAAAAATCACACAGGTTAGCATGGCCTCATTGAAAGAACTAGATCAAAGACTCTTTGAAAATTACATCGAGTTGAAAGCA GATCCCATCGTTGGCTCCTTAGAACCTGGAATTTATGCAGGATATTTTGATTGGAAGGACTGCCTGCCTCCAACAGGTGTCAGAAACTAT TTAAAAGAAGCACTGGTGAATATAATTGCCGTGCATGCAGAGGTGTTCACCATTTCCAAAGAACTGGTCCCTCGGGTACTATCCAAGGTG ATAGAAGCAGTTTCTGAAGAGCTCAGTCGACTGATGCAGTGTGTTTCATCCTTCAGCAAAAATGGAGCTTTACAGGCGAGACTTGAAATC TGTGCTTTGAGGGACACTGTGGCTGTTTACCTGACACCCGAAAGCAAGTCAAGTTTTAAGCAGGCTTTGGAAGCCCTGCCCCAGCTTTCC AGTGGAGCAGATAAAAAGTTACTGGAAGAGCTCCTGAACAAGTTCAAGAGTAGCATGCACTTGCAGCTCACCTGTTTCCAAGCAGCTTCT >In-frame_GMDS_ENST00000380815_chr6_1726650_-_EXOC2_ENST00000230449_chr6_556564_-_1911nt ATGGCACACGCACCGGCACGCTGCCCCAGCGCCCGGGGCTCCGGGGACGGCGAGATGGGCAAGCCCAGGAACGTGGCGCTCATCACCGGT ATCACAGGCCAGGATGGTTCCTACCTGGCTGAGTTCCTGCTGGAGAAAGGCTATGAGGTCCATGGAATTGTACGGCGGTCCAGTTCATTT AATACGGGTCGAATTGAGCATCTGTATAAGAATCCCCAGGCTCACATTGAAGGAAACATGAAGTTGCACTATGGCGATCTCACTGACAGT ACCTGCCTTGTGAAGATCATTAATGAAGTAAAGCCCACAGAGATCTACAACCTTGGAGCCCAGAGCCACGTCAAAATTTCCTTTGACCTC GCTGAGTACACTGCGGACGTTGACGGAGTTGGCACTCTACGACTTCTAGATGCAGTTAAGACTTGTGGCCTTATCAACTCTGTGAAGTTC TACCAAGCCTCAACAAGTGAACTTTATGGGAAAGTGCAGGAAATACCCCAGAAGGAGACCACCCCTTTCTATCCCCGGTCACCCTATGGG GCAGCAAAACTCTATGCCTATTGGATTGTGGTGAACTTCCGTGAGGCGTATAATCTCTTTGCAGTGAACGGCATTCTCTTCAATCATGAG AGTCCCAGAAGAGGAGCTAATTTCGTTACTCGAAAAATTAGCCGGTCAGTAGCTAAGATTTACCTTGGACAACTGGAATGTTTCAGTTTG GGAAATCTGGATGCCAAACGAGATTGGGGCCATGCCAAGGACTATGTGGAGGCTATGTGGTTGATGTTGCAGAATGATGAGCCGGAGGAC TTCGTTATAGCTACTGGGGAGGTCCATAGTGTCCGGGAATTTGTCGAGAAATCATTCTTGCACATTGGAAAAACCATTGTGTGGGAAGGA AAGAATGAAAATGAAGTGGGCAGATGTAAAGAGACCGGCAAAGTTCACGTGACTGTGGATCTCAAGTACTACCGGCCAACTGAAGTGCCA TGTCAGTTTGAACAGTGCATCGTGTGTTCTCTGCAGTCACTGAAGGGGGTTCTGGAGTGCAAGCCGGGAGAGGCCAGTGTCTTCCAACAA CCTAAAACACAGGAGGAGGTTTGCCAGCTAAGCATCAATATAATGCAGGTTTTTATATACTGTCTGGAACAGTTGAGCACCAAGCCTGAT GCAGATATAGATACTACACATCTCTCTGTTGATGTTTCTTCCCCTGACTTGTTTGGAAGTATCCATGAAGACTTCAGCTTGACCTCAGAA CAGCGCCTTTTGATAGTCCTAAGTAATTGCTGCTATCTAGAACGTCACACCTTCCTAAATATCGCAGAACATTTTGAAAAGCACAACTTC CAGGGAATAGAAAAAATCACACAGGTTAGCATGGCCTCATTGAAAGAACTAGATCAAAGACTCTTTGAAAATTACATCGAGTTGAAAGCA GATCCCATCGTTGGCTCCTTAGAACCTGGAATTTATGCAGGATATTTTGATTGGAAGGACTGCCTGCCTCCAACAGGTGTCAGAAACTAT TTAAAAGAAGCACTGGTGAATATAATTGCCGTGCATGCAGAGGTGTTCACCATTTCCAAAGAACTGGTCCCTCGGGTACTATCCAAGGTG ATAGAAGCAGTTTCTGAAGAGCTCAGTCGACTGATGCAGTGTGTTTCATCCTTCAGCAAAAATGGAGCTTTACAGGCGAGACTTGAAATC TGTGCTTTGAGGGACACTGTGGCTGTTTACCTGACACCCGAAAGCAAGTCAAGTTTTAAGCAGGCTTTGGAAGCCCTGCCCCAGCTTTCC AGTGGAGCAGATAAAAAGTTACTGGAAGAGCTCCTGAACAAGTTCAAGAGTAGCATGCACTTGCAGCTCACCTGTTTCCAAGCAGCTTCT >In-frame_GMDS_ENST00000380815_chr6_1726650_-_EXOC2_ENST00000448181_chr6_556564_-_1911nt ATGGCACACGCACCGGCACGCTGCCCCAGCGCCCGGGGCTCCGGGGACGGCGAGATGGGCAAGCCCAGGAACGTGGCGCTCATCACCGGT ATCACAGGCCAGGATGGTTCCTACCTGGCTGAGTTCCTGCTGGAGAAAGGCTATGAGGTCCATGGAATTGTACGGCGGTCCAGTTCATTT AATACGGGTCGAATTGAGCATCTGTATAAGAATCCCCAGGCTCACATTGAAGGAAACATGAAGTTGCACTATGGCGATCTCACTGACAGT ACCTGCCTTGTGAAGATCATTAATGAAGTAAAGCCCACAGAGATCTACAACCTTGGAGCCCAGAGCCACGTCAAAATTTCCTTTGACCTC GCTGAGTACACTGCGGACGTTGACGGAGTTGGCACTCTACGACTTCTAGATGCAGTTAAGACTTGTGGCCTTATCAACTCTGTGAAGTTC TACCAAGCCTCAACAAGTGAACTTTATGGGAAAGTGCAGGAAATACCCCAGAAGGAGACCACCCCTTTCTATCCCCGGTCACCCTATGGG GCAGCAAAACTCTATGCCTATTGGATTGTGGTGAACTTCCGTGAGGCGTATAATCTCTTTGCAGTGAACGGCATTCTCTTCAATCATGAG AGTCCCAGAAGAGGAGCTAATTTCGTTACTCGAAAAATTAGCCGGTCAGTAGCTAAGATTTACCTTGGACAACTGGAATGTTTCAGTTTG GGAAATCTGGATGCCAAACGAGATTGGGGCCATGCCAAGGACTATGTGGAGGCTATGTGGTTGATGTTGCAGAATGATGAGCCGGAGGAC TTCGTTATAGCTACTGGGGAGGTCCATAGTGTCCGGGAATTTGTCGAGAAATCATTCTTGCACATTGGAAAAACCATTGTGTGGGAAGGA AAGAATGAAAATGAAGTGGGCAGATGTAAAGAGACCGGCAAAGTTCACGTGACTGTGGATCTCAAGTACTACCGGCCAACTGAAGTGCCA TGTCAGTTTGAACAGTGCATCGTGTGTTCTCTGCAGTCACTGAAGGGGGTTCTGGAGTGCAAGCCGGGAGAGGCCAGTGTCTTCCAACAA CCTAAAACACAGGAGGAGGTTTGCCAGCTAAGCATCAATATAATGCAGGTTTTTATATACTGTCTGGAACAGTTGAGCACCAAGCCTGAT GCAGATATAGATACTACACATCTCTCTGTTGATGTTTCTTCCCCTGACTTGTTTGGAAGTATCCATGAAGACTTCAGCTTGACCTCAGAA CAGCGCCTTTTGATAGTCCTAAGTAATTGCTGCTATCTAGAACGTCACACCTTCCTAAATATCGCAGAACATTTTGAAAAGCACAACTTC CAGGGAATAGAAAAAATCACACAGGTTAGCATGGCCTCATTGAAAGAACTAGATCAAAGACTCTTTGAAAATTACATCGAGTTGAAAGCA GATCCCATCGTTGGCTCCTTAGAACCTGGAATTTATGCAGGATATTTTGATTGGAAGGACTGCCTGCCTCCAACAGGTGTCAGAAACTAT TTAAAAGAAGCACTGGTGAATATAATTGCCGTGCATGCAGAGGTGTTCACCATTTCCAAAGAACTGGTCCCTCGGGTACTATCCAAGGTG ATAGAAGCAGTTTCTGAAGAGCTCAGTCGACTGATGCAGTGTGTTTCATCCTTCAGCAAAAATGGAGCTTTACAGGCGAGACTTGAAATC TGTGCTTTGAGGGACACTGTGGCTGTTTACCTGACACCCGAAAGCAAGTCAAGTTTTAAGCAGGCTTTGGAAGCCCTGCCCCAGCTTTCC AGTGGAGCAGATAAAAAGTTACTGGAAGAGCTCCTGAACAAGTTCAAGAGTAGCATGCACTTGCAGCTCACCTGTTTCCAAGCAGCTTCT |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_GMDS_ENST00000530927_chr6_1726650_-_EXOC2_ENST00000230449_chr6_556564_-_3407nt TGTACACAGGCAGTTTGTTGGGAGCGTTACCATTGCCTCTGGTTCCTCATGTGTAAAATGGATGGTTCCTACCTGGCTGAGTTCCTGCTG GAGAAAGGCTATGAGGTCCATGGAATTGTACGGCGGTCCAGTTCATTTAATACGGGTCGAATTGAGCATCTGTATAAGAATCCCCAGGCT CACATTGAAGGAAACATGAAGTTGCACTATGGCGATCTCACTGACAGTACCTGCCTTGTGAAGATCATTAATGAAGTAAAGCCCACAGAG ATCTACAACCTTGGAGCCCAGAGCCACGTCAAAATTTCCTTTGACCTCGCTGAGTACACTGCGGACGTTGACGGAGTTGGCACTCTACGA CTTCTAGATGCAGTTAAGACTTGTGGCCTTATCAACTCTGTGAAGTTCTACCAAGCCTCAACAAGTGAACTTTATGGGAAAGTGCAGGAA ATACCCCAGAAGGAGACCACCCCTTTCTATCCCCGGTCACCCTATGGGGCAGCAAAACTCTATGCCTATTGGATTGTGGTGAACTTCCGT GAGGCGTATAATCTCTTTGCAGTGAACGGCATTCTCTTCAATCATGAGAGTCCCAGAAGAGGAGCTAATTTCGTTACTCGAAAAATTAGC CGGTCAGTAGCTAAGATTTACCTTGGACAACTGGAATGTTTCAGTTTGGGAAATCTGGATGCCAAACGAGATTGGGGCCATGCCAAGGAC TATGTGGAGGCTATGTGGTTGATGTTGCAGAATGATGAGCCGGAGGACTTCGTTATAGCTACTGGGGAGGTCCATAGTGTCCGGGAATTT GTCGAGAAATCATTCTTGCACATTGGAAAAACCATTGTGTGGGAAGGAAAGAATGAAAATGAAGTGGGCAGATGTAAAGAGACCGGCAAA GTTCACGTGACTGTGGATCTCAAGTACTACCGGCCAACTGAAGTGCCATGTCAGTTTGAACAGTGCATCGTGTGTTCTCTGCAGTCACTG AAGGGGGTTCTGGAGTGCAAGCCGGGAGAGGCCAGTGTCTTCCAACAACCTAAAACACAGGAGGAGGTTTGCCAGCTAAGCATCAATATA ATGCAGGTTTTTATATACTGTCTGGAACAGTTGAGCACCAAGCCTGATGCAGATATAGATACTACACATCTCTCTGTTGATGTTTCTTCC CCTGACTTGTTTGGAAGTATCCATGAAGACTTCAGCTTGACCTCAGAACAGCGCCTTTTGATAGTCCTAAGTAATTGCTGCTATCTAGAA CGTCACACCTTCCTAAATATCGCAGAACATTTTGAAAAGCACAACTTCCAGGGAATAGAAAAAATCACACAGGTTAGCATGGCCTCATTG AAAGAACTAGATCAAAGACTCTTTGAAAATTACATCGAGTTGAAAGCAGATCCCATCGTTGGCTCCTTAGAACCTGGAATTTATGCAGGA TATTTTGATTGGAAGGACTGCCTGCCTCCAACAGGTGTCAGAAACTATTTAAAAGAAGCACTGGTGAATATAATTGCCGTGCATGCAGAG GTGTTCACCATTTCCAAAGAACTGGTCCCTCGGGTACTATCCAAGGTGATAGAAGCAGTTTCTGAAGAGCTCAGTCGACTGATGCAGTGT GTTTCATCCTTCAGCAAAAATGGAGCTTTACAGGCGAGACTTGAAATCTGTGCTTTGAGGGACACTGTGGCTGTTTACCTGACACCCGAA AGCAAGTCAAGTTTTAAGCAGGCTTTGGAAGCCCTGCCCCAGCTTTCCAGTGGAGCAGATAAAAAGTTACTGGAAGAGCTCCTGAACAAG TTCAAGAGTAGCATGCACTTGCAGCTCACCTGTTTCCAAGCAGCTTCTTCAACCATGATGAAAACATAAATATCTGCCACATAAAAGAAG TCCAGGAAAATAACACGTAATAAGACTGTTCACTCTCTAAGTACCCTAAAGGTATTTGGTGTATTAAACATTGGGTTTGCCATTTTTCTC TTTTTTCTTCCTCTGACTTCGAAAATTGTTGGTATACATTTCAACCAAAATGACCTCATTTGAAATGCCCAGGAAGTATTTGTTTTGCCA TTCTTACTAGATCAGATCCTGTATGACTTTAAAATACATTTTAAAATATATTTTGCATCTCAGCAGAAGGTTGAGTGCTGCAGGAAGAGC TGCTTCTGCAGGGAGTTTTCTGGAATGGCGTGGCACATATTGAAGCATTTCTCAGTGTCCCGTTCACGGAAGCGCAGGCAGCTCCCACGA CACACGGAGAGACTGACTGATACGAGATTTGGAAAGCTATGTAGACATCTTTGGAGCTCTTACTGTCCTAAACTGTACAGCTGTGCTTAA AACCCTCATTTCATATAAATGGCCTTAAGTTTTCTAATTCAAGCGGGTTTTTGGAAAAATTTATGGTCTCCATTAAAATACATATTACAA CTGGGGTAGATTATTTGTGGTCCAGGTGTCTGTGATTTAACTTTGCGTTTTGCTATCTGATTTTTATTTTTCACAGGGCTAAGCATGAGC TTTCATTCTCACTCACTCTTAATTTGTCGTGCGTCACTACACATGCACGTGTTGCAGTCCCTGAGGCCCTGTGTGTTATCTGTGATGGAG TGTGAATGTGTAACGGGCACTGTGTTACACTCTGAGGTGTTGGCGGGGCGGTCGCAGACTTCAGGGTCCCCTAACGGAAAGGCCAGGCTC CGCGTGGACGGCCAACTCCCTGCCCGCTCCTTCAGCAGGTGACTGTCTCTGCCACTTCTTACCTGCTGAAGGATCTTGCTCAGTAGCTGG AACAATGCTGCTGTCACACAGTCTCTTCTCTGAAACTTCAGGATGCTCCTTGGTCACCAGGCAATGGGAGCTGTAGACCAGCCGCATGCA CTTGCCCCACATTCACTGCTGACTGGCTTCACTGGAATAGGTTCAGGTCACCGGGACTTCTCTCAGAGTCAGCGGCCCACCCAACTCCCT CATACCGTCGCATCTGAAAATTTTCAGAGAGGAATTCTCTTTGTAGTCGGCTTGTCAGGGTTTTCAAGTTTTTCTATGGTTATTTTTAAA TCTCTTTTTTTAAATGCTAAAATTAATGTCCTCATTAATGCAAGTAATTTTAGAGCACAGTGTAGCCATGTACAGTTTCCATTATTTAAA ATAAATAAATGTGTTGGTTCATTTGGTGTATGGGGGGACATCATGGTAACTGGAAATGAAAGTTTAATCTTTCACAAATGTGCTTGATAA AGCTGTTAAGAATTGTCTTTCCTAAGTATGTTAACTGTTGTATCTAACTCAACTGTGAGCTAAGTTTAAAAACTGCAATCATGAATGTTT >In-frame_GMDS_ENST00000530927_chr6_1726650_-_EXOC2_ENST00000448181_chr6_556564_-_2022nt TGTACACAGGCAGTTTGTTGGGAGCGTTACCATTGCCTCTGGTTCCTCATGTGTAAAATGGATGGTTCCTACCTGGCTGAGTTCCTGCTG GAGAAAGGCTATGAGGTCCATGGAATTGTACGGCGGTCCAGTTCATTTAATACGGGTCGAATTGAGCATCTGTATAAGAATCCCCAGGCT CACATTGAAGGAAACATGAAGTTGCACTATGGCGATCTCACTGACAGTACCTGCCTTGTGAAGATCATTAATGAAGTAAAGCCCACAGAG ATCTACAACCTTGGAGCCCAGAGCCACGTCAAAATTTCCTTTGACCTCGCTGAGTACACTGCGGACGTTGACGGAGTTGGCACTCTACGA CTTCTAGATGCAGTTAAGACTTGTGGCCTTATCAACTCTGTGAAGTTCTACCAAGCCTCAACAAGTGAACTTTATGGGAAAGTGCAGGAA ATACCCCAGAAGGAGACCACCCCTTTCTATCCCCGGTCACCCTATGGGGCAGCAAAACTCTATGCCTATTGGATTGTGGTGAACTTCCGT GAGGCGTATAATCTCTTTGCAGTGAACGGCATTCTCTTCAATCATGAGAGTCCCAGAAGAGGAGCTAATTTCGTTACTCGAAAAATTAGC CGGTCAGTAGCTAAGATTTACCTTGGACAACTGGAATGTTTCAGTTTGGGAAATCTGGATGCCAAACGAGATTGGGGCCATGCCAAGGAC TATGTGGAGGCTATGTGGTTGATGTTGCAGAATGATGAGCCGGAGGACTTCGTTATAGCTACTGGGGAGGTCCATAGTGTCCGGGAATTT GTCGAGAAATCATTCTTGCACATTGGAAAAACCATTGTGTGGGAAGGAAAGAATGAAAATGAAGTGGGCAGATGTAAAGAGACCGGCAAA GTTCACGTGACTGTGGATCTCAAGTACTACCGGCCAACTGAAGTGCCATGTCAGTTTGAACAGTGCATCGTGTGTTCTCTGCAGTCACTG AAGGGGGTTCTGGAGTGCAAGCCGGGAGAGGCCAGTGTCTTCCAACAACCTAAAACACAGGAGGAGGTTTGCCAGCTAAGCATCAATATA ATGCAGGTTTTTATATACTGTCTGGAACAGTTGAGCACCAAGCCTGATGCAGATATAGATACTACACATCTCTCTGTTGATGTTTCTTCC CCTGACTTGTTTGGAAGTATCCATGAAGACTTCAGCTTGACCTCAGAACAGCGCCTTTTGATAGTCCTAAGTAATTGCTGCTATCTAGAA CGTCACACCTTCCTAAATATCGCAGAACATTTTGAAAAGCACAACTTCCAGGGAATAGAAAAAATCACACAGGTTAGCATGGCCTCATTG AAAGAACTAGATCAAAGACTCTTTGAAAATTACATCGAGTTGAAAGCAGATCCCATCGTTGGCTCCTTAGAACCTGGAATTTATGCAGGA TATTTTGATTGGAAGGACTGCCTGCCTCCAACAGGTGTCAGAAACTATTTAAAAGAAGCACTGGTGAATATAATTGCCGTGCATGCAGAG GTGTTCACCATTTCCAAAGAACTGGTCCCTCGGGTACTATCCAAGGTGATAGAAGCAGTTTCTGAAGAGCTCAGTCGACTGATGCAGTGT GTTTCATCCTTCAGCAAAAATGGAGCTTTACAGGCGAGACTTGAAATCTGTGCTTTGAGGGACACTGTGGCTGTTTACCTGACACCCGAA AGCAAGTCAAGTTTTAAGCAGGCTTTGGAAGCCCTGCCCCAGCTTTCCAGTGGAGCAGATAAAAAGTTACTGGAAGAGCTCCTGAACAAG TTCAAGAGTAGCATGCACTTGCAGCTCACCTGTTTCCAAGCAGCTTCTTCAACCATGATGAAAACATAAATATCTGCCACATAAAAGAAG TCCAGGAAAATAACACGTAATAAGACTGTTCACTCTCTAAGTACCCTAAAGGTATTTGGTGTATTAAACATTGGGTTTGCCATTTTTCTC >In-frame_GMDS_ENST00000380815_chr6_1726650_-_EXOC2_ENST00000230449_chr6_556564_-_3719nt GACGCGAATGACGCTGCGCCAGTCAGGCCGCAGCCCCGCTGCTTGGCCCGTCGGGCCCGCCTTGGCCGGCTCGGCCCGCCCCCGGCCCTC CCTGCACGGCCTCCCGTGCGCCCCTGTCAGACTGTGGCGGCCGGTCGCGCGGTGCGCTCTCCCTCCCTGCCCGCAGCCTGGAGAGGCGCT TCGTGCTGCACACCCCCGCGTTCCTGCCGGCACCGCGCCTGCCCTCTGCCGCGCTCCGCCCTGCCGCCGACCGCACGCCCGCCGCGGGAC ATGGCACACGCACCGGCACGCTGCCCCAGCGCCCGGGGCTCCGGGGACGGCGAGATGGGCAAGCCCAGGAACGTGGCGCTCATCACCGGT ATCACAGGCCAGGATGGTTCCTACCTGGCTGAGTTCCTGCTGGAGAAAGGCTATGAGGTCCATGGAATTGTACGGCGGTCCAGTTCATTT AATACGGGTCGAATTGAGCATCTGTATAAGAATCCCCAGGCTCACATTGAAGGAAACATGAAGTTGCACTATGGCGATCTCACTGACAGT ACCTGCCTTGTGAAGATCATTAATGAAGTAAAGCCCACAGAGATCTACAACCTTGGAGCCCAGAGCCACGTCAAAATTTCCTTTGACCTC GCTGAGTACACTGCGGACGTTGACGGAGTTGGCACTCTACGACTTCTAGATGCAGTTAAGACTTGTGGCCTTATCAACTCTGTGAAGTTC TACCAAGCCTCAACAAGTGAACTTTATGGGAAAGTGCAGGAAATACCCCAGAAGGAGACCACCCCTTTCTATCCCCGGTCACCCTATGGG GCAGCAAAACTCTATGCCTATTGGATTGTGGTGAACTTCCGTGAGGCGTATAATCTCTTTGCAGTGAACGGCATTCTCTTCAATCATGAG AGTCCCAGAAGAGGAGCTAATTTCGTTACTCGAAAAATTAGCCGGTCAGTAGCTAAGATTTACCTTGGACAACTGGAATGTTTCAGTTTG GGAAATCTGGATGCCAAACGAGATTGGGGCCATGCCAAGGACTATGTGGAGGCTATGTGGTTGATGTTGCAGAATGATGAGCCGGAGGAC TTCGTTATAGCTACTGGGGAGGTCCATAGTGTCCGGGAATTTGTCGAGAAATCATTCTTGCACATTGGAAAAACCATTGTGTGGGAAGGA AAGAATGAAAATGAAGTGGGCAGATGTAAAGAGACCGGCAAAGTTCACGTGACTGTGGATCTCAAGTACTACCGGCCAACTGAAGTGCCA TGTCAGTTTGAACAGTGCATCGTGTGTTCTCTGCAGTCACTGAAGGGGGTTCTGGAGTGCAAGCCGGGAGAGGCCAGTGTCTTCCAACAA CCTAAAACACAGGAGGAGGTTTGCCAGCTAAGCATCAATATAATGCAGGTTTTTATATACTGTCTGGAACAGTTGAGCACCAAGCCTGAT GCAGATATAGATACTACACATCTCTCTGTTGATGTTTCTTCCCCTGACTTGTTTGGAAGTATCCATGAAGACTTCAGCTTGACCTCAGAA CAGCGCCTTTTGATAGTCCTAAGTAATTGCTGCTATCTAGAACGTCACACCTTCCTAAATATCGCAGAACATTTTGAAAAGCACAACTTC CAGGGAATAGAAAAAATCACACAGGTTAGCATGGCCTCATTGAAAGAACTAGATCAAAGACTCTTTGAAAATTACATCGAGTTGAAAGCA GATCCCATCGTTGGCTCCTTAGAACCTGGAATTTATGCAGGATATTTTGATTGGAAGGACTGCCTGCCTCCAACAGGTGTCAGAAACTAT TTAAAAGAAGCACTGGTGAATATAATTGCCGTGCATGCAGAGGTGTTCACCATTTCCAAAGAACTGGTCCCTCGGGTACTATCCAAGGTG ATAGAAGCAGTTTCTGAAGAGCTCAGTCGACTGATGCAGTGTGTTTCATCCTTCAGCAAAAATGGAGCTTTACAGGCGAGACTTGAAATC TGTGCTTTGAGGGACACTGTGGCTGTTTACCTGACACCCGAAAGCAAGTCAAGTTTTAAGCAGGCTTTGGAAGCCCTGCCCCAGCTTTCC AGTGGAGCAGATAAAAAGTTACTGGAAGAGCTCCTGAACAAGTTCAAGAGTAGCATGCACTTGCAGCTCACCTGTTTCCAAGCAGCTTCT TCAACCATGATGAAAACATAAATATCTGCCACATAAAAGAAGTCCAGGAAAATAACACGTAATAAGACTGTTCACTCTCTAAGTACCCTA AAGGTATTTGGTGTATTAAACATTGGGTTTGCCATTTTTCTCTTTTTTCTTCCTCTGACTTCGAAAATTGTTGGTATACATTTCAACCAA AATGACCTCATTTGAAATGCCCAGGAAGTATTTGTTTTGCCATTCTTACTAGATCAGATCCTGTATGACTTTAAAATACATTTTAAAATA TATTTTGCATCTCAGCAGAAGGTTGAGTGCTGCAGGAAGAGCTGCTTCTGCAGGGAGTTTTCTGGAATGGCGTGGCACATATTGAAGCAT TTCTCAGTGTCCCGTTCACGGAAGCGCAGGCAGCTCCCACGACACACGGAGAGACTGACTGATACGAGATTTGGAAAGCTATGTAGACAT CTTTGGAGCTCTTACTGTCCTAAACTGTACAGCTGTGCTTAAAACCCTCATTTCATATAAATGGCCTTAAGTTTTCTAATTCAAGCGGGT TTTTGGAAAAATTTATGGTCTCCATTAAAATACATATTACAACTGGGGTAGATTATTTGTGGTCCAGGTGTCTGTGATTTAACTTTGCGT TTTGCTATCTGATTTTTATTTTTCACAGGGCTAAGCATGAGCTTTCATTCTCACTCACTCTTAATTTGTCGTGCGTCACTACACATGCAC GTGTTGCAGTCCCTGAGGCCCTGTGTGTTATCTGTGATGGAGTGTGAATGTGTAACGGGCACTGTGTTACACTCTGAGGTGTTGGCGGGG CGGTCGCAGACTTCAGGGTCCCCTAACGGAAAGGCCAGGCTCCGCGTGGACGGCCAACTCCCTGCCCGCTCCTTCAGCAGGTGACTGTCT CTGCCACTTCTTACCTGCTGAAGGATCTTGCTCAGTAGCTGGAACAATGCTGCTGTCACACAGTCTCTTCTCTGAAACTTCAGGATGCTC CTTGGTCACCAGGCAATGGGAGCTGTAGACCAGCCGCATGCACTTGCCCCACATTCACTGCTGACTGGCTTCACTGGAATAGGTTCAGGT CACCGGGACTTCTCTCAGAGTCAGCGGCCCACCCAACTCCCTCATACCGTCGCATCTGAAAATTTTCAGAGAGGAATTCTCTTTGTAGTC GGCTTGTCAGGGTTTTCAAGTTTTTCTATGGTTATTTTTAAATCTCTTTTTTTAAATGCTAAAATTAATGTCCTCATTAATGCAAGTAAT TTTAGAGCACAGTGTAGCCATGTACAGTTTCCATTATTTAAAATAAATAAATGTGTTGGTTCATTTGGTGTATGGGGGGACATCATGGTA ACTGGAAATGAAAGTTTAATCTTTCACAAATGTGCTTGATAAAGCTGTTAAGAATTGTCTTTCCTAAGTATGTTAACTGTTGTATCTAAC TCAACTGTGAGCTAAGTTTAAAAACTGCAATCATGAATGTTTGTGATATTTTAAATATCTACTACAGCACATTCAGCCAATAAAGAATCT >In-frame_GMDS_ENST00000380815_chr6_1726650_-_EXOC2_ENST00000448181_chr6_556564_-_2334nt GACGCGAATGACGCTGCGCCAGTCAGGCCGCAGCCCCGCTGCTTGGCCCGTCGGGCCCGCCTTGGCCGGCTCGGCCCGCCCCCGGCCCTC CCTGCACGGCCTCCCGTGCGCCCCTGTCAGACTGTGGCGGCCGGTCGCGCGGTGCGCTCTCCCTCCCTGCCCGCAGCCTGGAGAGGCGCT TCGTGCTGCACACCCCCGCGTTCCTGCCGGCACCGCGCCTGCCCTCTGCCGCGCTCCGCCCTGCCGCCGACCGCACGCCCGCCGCGGGAC ATGGCACACGCACCGGCACGCTGCCCCAGCGCCCGGGGCTCCGGGGACGGCGAGATGGGCAAGCCCAGGAACGTGGCGCTCATCACCGGT ATCACAGGCCAGGATGGTTCCTACCTGGCTGAGTTCCTGCTGGAGAAAGGCTATGAGGTCCATGGAATTGTACGGCGGTCCAGTTCATTT AATACGGGTCGAATTGAGCATCTGTATAAGAATCCCCAGGCTCACATTGAAGGAAACATGAAGTTGCACTATGGCGATCTCACTGACAGT ACCTGCCTTGTGAAGATCATTAATGAAGTAAAGCCCACAGAGATCTACAACCTTGGAGCCCAGAGCCACGTCAAAATTTCCTTTGACCTC GCTGAGTACACTGCGGACGTTGACGGAGTTGGCACTCTACGACTTCTAGATGCAGTTAAGACTTGTGGCCTTATCAACTCTGTGAAGTTC TACCAAGCCTCAACAAGTGAACTTTATGGGAAAGTGCAGGAAATACCCCAGAAGGAGACCACCCCTTTCTATCCCCGGTCACCCTATGGG GCAGCAAAACTCTATGCCTATTGGATTGTGGTGAACTTCCGTGAGGCGTATAATCTCTTTGCAGTGAACGGCATTCTCTTCAATCATGAG AGTCCCAGAAGAGGAGCTAATTTCGTTACTCGAAAAATTAGCCGGTCAGTAGCTAAGATTTACCTTGGACAACTGGAATGTTTCAGTTTG GGAAATCTGGATGCCAAACGAGATTGGGGCCATGCCAAGGACTATGTGGAGGCTATGTGGTTGATGTTGCAGAATGATGAGCCGGAGGAC TTCGTTATAGCTACTGGGGAGGTCCATAGTGTCCGGGAATTTGTCGAGAAATCATTCTTGCACATTGGAAAAACCATTGTGTGGGAAGGA AAGAATGAAAATGAAGTGGGCAGATGTAAAGAGACCGGCAAAGTTCACGTGACTGTGGATCTCAAGTACTACCGGCCAACTGAAGTGCCA TGTCAGTTTGAACAGTGCATCGTGTGTTCTCTGCAGTCACTGAAGGGGGTTCTGGAGTGCAAGCCGGGAGAGGCCAGTGTCTTCCAACAA CCTAAAACACAGGAGGAGGTTTGCCAGCTAAGCATCAATATAATGCAGGTTTTTATATACTGTCTGGAACAGTTGAGCACCAAGCCTGAT GCAGATATAGATACTACACATCTCTCTGTTGATGTTTCTTCCCCTGACTTGTTTGGAAGTATCCATGAAGACTTCAGCTTGACCTCAGAA CAGCGCCTTTTGATAGTCCTAAGTAATTGCTGCTATCTAGAACGTCACACCTTCCTAAATATCGCAGAACATTTTGAAAAGCACAACTTC CAGGGAATAGAAAAAATCACACAGGTTAGCATGGCCTCATTGAAAGAACTAGATCAAAGACTCTTTGAAAATTACATCGAGTTGAAAGCA GATCCCATCGTTGGCTCCTTAGAACCTGGAATTTATGCAGGATATTTTGATTGGAAGGACTGCCTGCCTCCAACAGGTGTCAGAAACTAT TTAAAAGAAGCACTGGTGAATATAATTGCCGTGCATGCAGAGGTGTTCACCATTTCCAAAGAACTGGTCCCTCGGGTACTATCCAAGGTG ATAGAAGCAGTTTCTGAAGAGCTCAGTCGACTGATGCAGTGTGTTTCATCCTTCAGCAAAAATGGAGCTTTACAGGCGAGACTTGAAATC TGTGCTTTGAGGGACACTGTGGCTGTTTACCTGACACCCGAAAGCAAGTCAAGTTTTAAGCAGGCTTTGGAAGCCCTGCCCCAGCTTTCC AGTGGAGCAGATAAAAAGTTACTGGAAGAGCTCCTGAACAAGTTCAAGAGTAGCATGCACTTGCAGCTCACCTGTTTCCAAGCAGCTTCT TCAACCATGATGAAAACATAAATATCTGCCACATAAAAGAAGTCCAGGAAAATAACACGTAATAAGACTGTTCACTCTCTAAGTACCCTA |
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FusionGenePPI for GMDS_EXOC2 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| GMDS | GMDS, TNKS, BLVRB, BAG3, ATIC, CAPN2, CTH, NSFL1C, PTMA, RAP1GDS1, TATDN1, WDYHV1, RNF166, MAT2B, RAB2A, TTC5, NDUFA9, PSMG4, CCDC22, SKA1, NF2, FBXW7, TNKS2, HIF1AN, NPHP3 | EXOC2 | EXOC8, RALB, RALA, SERGEF, VPS53, EXOC4, EXOC3, EXOC7, EXOC5, EXOC6, GET4, ESX1, TBK1, BECN1, USP33, KIAA0226, ATG14, PIK3C3, ULK1, SHMT2, MOV10, NXF1, BSG, LPAR6, PTGER3, SCN2B, SCARA3, HTR6, EXOC1, PGM1, SPTBN2, NTRK1, RANBP9, SNW1, CDC5L, PTAR1, IL1R2, EDNRB, APLNR, CHRM3, EXOC6B, CDKN2A |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for GMDS_EXOC2 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for GMDS_EXOC2 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
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