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Center for Computational Systems Medicine
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FusionGeneSummary

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FusionProtFeature

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FusionGeneSequence

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FusionGenePPI

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RelatedDiseases

Fusion gene ID: 14725

FusionGeneSummary for GLIS3_CTNNA2

check button Fusion gene summary
Fusion gene informationFusion gene name: GLIS3_CTNNA2
Fusion gene ID: 14725
HgeneTgene
Gene symbol

GLIS3

CTNNA2

Gene ID

169792

1496

Gene nameGLIS family zinc finger 3catenin alpha 2
SynonymsNDH|ZNF515CAP-R|CAPR|CT114|CTNR
Cytomap

9p24.2

2p12

Type of geneprotein-codingprotein-coding
Descriptionzinc finger protein GLIS3GLI-similar 3OK/KNS-cl.4zinc finger protein 515catenin alpha-2alpha-N-cateninalpha-catenin-related proteincadherin-associated protein, relatedcancer/testis antigen 114catenin (cadherin-associated protein), alpha 2
Modification date2018052720180522
UniProtAcc

Q8NEA6

P26232

Ensembl transtripts involved in fusion geneENST00000381971, ENST00000324333, 
ENST00000461870, 
ENST00000466387, 
ENST00000496558, ENST00000361291, 
ENST00000402739, ENST00000540488, 
ENST00000541047, ENST00000343114, 
ENST00000496251, ENST00000409266, 
Fusion gene scores* DoF score10 X 5 X 7=35015 X 12 X 9=1620
# samples 1015
** MAII scorelog2(10/350*10)=-1.8073549220576
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
log2(15/1620*10)=-3.43295940727611
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: GLIS3 [Title/Abstract] AND CTNNA2 [Title/Abstract] AND fusion [Title/Abstract]

Functional or gene categories assigned by FusionGDB annotation
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check button Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
Data typeSourceCancer typeSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
TCGARVHNSCTCGA-CN-5365-01AGLIS3chr9

4117768

-CTNNA2chr2

80874710

+
* LD: Li Ding group's fusion gene list
  RV: Roel Verhaak group's fusion gene list
  ChiTaRs fusion database

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
Frame-shitENST00000381971ENST00000466387GLIS3chr9

4117768

-CTNNA2chr2

80874710

+
Frame-shitENST00000381971ENST00000496558GLIS3chr9

4117768

-CTNNA2chr2

80874710

+
In-frameENST00000381971ENST00000361291GLIS3chr9

4117768

-CTNNA2chr2

80874710

+
Frame-shitENST00000381971ENST00000402739GLIS3chr9

4117768

-CTNNA2chr2

80874710

+
In-frameENST00000381971ENST00000540488GLIS3chr9

4117768

-CTNNA2chr2

80874710

+
Frame-shitENST00000381971ENST00000541047GLIS3chr9

4117768

-CTNNA2chr2

80874710

+
Frame-shitENST00000381971ENST00000343114GLIS3chr9

4117768

-CTNNA2chr2

80874710

+
5CDS-intronENST00000381971ENST00000496251GLIS3chr9

4117768

-CTNNA2chr2

80874710

+
5CDS-intronENST00000381971ENST00000409266GLIS3chr9

4117768

-CTNNA2chr2

80874710

+
In-frameENST00000324333ENST00000466387GLIS3chr9

4117768

-CTNNA2chr2

80874710

+
Frame-shitENST00000324333ENST00000496558GLIS3chr9

4117768

-CTNNA2chr2

80874710

+
Frame-shitENST00000324333ENST00000361291GLIS3chr9

4117768

-CTNNA2chr2

80874710

+
In-frameENST00000324333ENST00000402739GLIS3chr9

4117768

-CTNNA2chr2

80874710

+
Frame-shitENST00000324333ENST00000540488GLIS3chr9

4117768

-CTNNA2chr2

80874710

+
In-frameENST00000324333ENST00000541047GLIS3chr9

4117768

-CTNNA2chr2

80874710

+
Frame-shitENST00000324333ENST00000343114GLIS3chr9

4117768

-CTNNA2chr2

80874710

+
5CDS-intronENST00000324333ENST00000496251GLIS3chr9

4117768

-CTNNA2chr2

80874710

+
5CDS-intronENST00000324333ENST00000409266GLIS3chr9

4117768

-CTNNA2chr2

80874710

+
intron-3CDSENST00000461870ENST00000466387GLIS3chr9

4117768

-CTNNA2chr2

80874710

+
intron-3CDSENST00000461870ENST00000496558GLIS3chr9

4117768

-CTNNA2chr2

80874710

+
intron-3CDSENST00000461870ENST00000361291GLIS3chr9

4117768

-CTNNA2chr2

80874710

+
intron-3CDSENST00000461870ENST00000402739GLIS3chr9

4117768

-CTNNA2chr2

80874710

+
intron-3CDSENST00000461870ENST00000540488GLIS3chr9

4117768

-CTNNA2chr2

80874710

+
intron-3CDSENST00000461870ENST00000541047GLIS3chr9

4117768

-CTNNA2chr2

80874710

+
intron-3CDSENST00000461870ENST00000343114GLIS3chr9

4117768

-CTNNA2chr2

80874710

+
intron-intronENST00000461870ENST00000496251GLIS3chr9

4117768

-CTNNA2chr2

80874710

+
intron-intronENST00000461870ENST00000409266GLIS3chr9

4117768

-CTNNA2chr2

80874710

+

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FusionProtFeatures for GLIS3_CTNNA2


check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
GLIS3

Q8NEA6

CTNNA2

P26232

Acts as both a repressor and activator of transcription.Binds to the consensus sequence 5'-GACCACCCAC-3' (By similarity).{ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

.

* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note


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FusionGeneSequence for GLIS3_CTNNA2


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.
>In-frame_GLIS3_ENST00000381971_chr9_4117768_-_CTNNA2_ENST00000361291_chr2_80874710_+_666aa
MNGRSCSMSLHRTSGTPQGPRMVSGHHIPAIRAHSGTPGPSPCGSTSSPTMASLANNLHLKMPSGGGMAPQNNVAESRIHLPALSPRRQM
LTNGKPRFQVTQAGGMSGSHTLKPKQQEFGSPFPPNPGKGALGFGPQCKSIGKGSCNNLVVTSSPMMVQRLGLISPPASQVSTACNQISP
SLQRAMNAANLNIPPSDTRSLISRESLASTTLSLTESQSASSMKQEWSQGYRALPSLSNHGSQNGLDLGDLLSLPPGTSMSSNSVSNSLP
SYLFGTESSHSPYPSPRHSSTRSHSARSKKRALSLSPLSDGIGIDFNTIIRTSPTSLVAYINGSRASPANLSPQPEVYGHFLGVRGSCIP
QPRPVPGSQKGVLVAPGGLALPAYGEDGALEHERMQQLEHGGLQPGLVNHMVVQHGLPGPDSQSAGLFKTERLEEFPGSTVDLPPAPPLP
PLPPPPGPPPPYHAHAHLHHPELGPHAQQLALPQATLDDDGEMDGIGGKHCCRWIDCSALYDQQEELVRHIEKVHIDQRKGEDFTCFWAG
CPRRYKPFNARTKLLIHMRVHSGEKPNKCTLDSATSLIQAAKNLMNAVVLTVKASTVASTKYQKVTGTAAVNSPVVSWKMKAPEKKPLVK

>In-frame_GLIS3_ENST00000381971_chr9_4117768_-_CTNNA2_ENST00000540488_chr2_80874710_+_666aa
MNGRSCSMSLHRTSGTPQGPRMVSGHHIPAIRAHSGTPGPSPCGSTSSPTMASLANNLHLKMPSGGGMAPQNNVAESRIHLPALSPRRQM
LTNGKPRFQVTQAGGMSGSHTLKPKQQEFGSPFPPNPGKGALGFGPQCKSIGKGSCNNLVVTSSPMMVQRLGLISPPASQVSTACNQISP
SLQRAMNAANLNIPPSDTRSLISRESLASTTLSLTESQSASSMKQEWSQGYRALPSLSNHGSQNGLDLGDLLSLPPGTSMSSNSVSNSLP
SYLFGTESSHSPYPSPRHSSTRSHSARSKKRALSLSPLSDGIGIDFNTIIRTSPTSLVAYINGSRASPANLSPQPEVYGHFLGVRGSCIP
QPRPVPGSQKGVLVAPGGLALPAYGEDGALEHERMQQLEHGGLQPGLVNHMVVQHGLPGPDSQSAGLFKTERLEEFPGSTVDLPPAPPLP
PLPPPPGPPPPYHAHAHLHHPELGPHAQQLALPQATLDDDGEMDGIGGKHCCRWIDCSALYDQQEELVRHIEKVHIDQRKGEDFTCFWAG
CPRRYKPFNARTKLLIHMRVHSGEKPNKCTLDSATSLIQAAKNLMNAVVLTVKASTVASTKYQKVTGTAAVNSPVVSWKMKAPEKKPLVK

>In-frame_GLIS3_ENST00000324333_chr9_4117768_-_CTNNA2_ENST00000466387_chr2_80874710_+_511aa
MMVQRLGLISPPASQVSTACNQISPSLQRAMNAANLNIPPSDTRSLISRESLASTTLSLTESQSASSMKQEWSQGYRALPSLSNHGSQNG
LDLGDLLSLPPGTSMSSNSVSNSLPSYLFGTESSHSPYPSPRHSSTRSHSARSKKRALSLSPLSDGIGIDFNTIIRTSPTSLVAYINGSR
ASPANLSPQPEVYGHFLGVRGSCIPQPRPVPGSQKGVLVAPGGLALPAYGEDGALEHERMQQLEHGGLQPGLVNHMVVQHGLPGPDSQSA
GLFKTERLEEFPGSTVDLPPAPPLPPLPPPPGPPPPYHAHAHLHHPELGPHAQQLALPQATLDDDGEMDGIGGKHCCRWIDCSALYDQQE
ELVRHIEKVHIDQRKGEDFTCFWAGCPRRYKPFNARTKLLIHMRVHSGEKPNKCTLDSATSLIQAAKNLMNAVVLTVKASTVASTKYQKV

>In-frame_GLIS3_ENST00000324333_chr9_4117768_-_CTNNA2_ENST00000402739_chr2_80874710_+_511aa
MMVQRLGLISPPASQVSTACNQISPSLQRAMNAANLNIPPSDTRSLISRESLASTTLSLTESQSASSMKQEWSQGYRALPSLSNHGSQNG
LDLGDLLSLPPGTSMSSNSVSNSLPSYLFGTESSHSPYPSPRHSSTRSHSARSKKRALSLSPLSDGIGIDFNTIIRTSPTSLVAYINGSR
ASPANLSPQPEVYGHFLGVRGSCIPQPRPVPGSQKGVLVAPGGLALPAYGEDGALEHERMQQLEHGGLQPGLVNHMVVQHGLPGPDSQSA
GLFKTERLEEFPGSTVDLPPAPPLPPLPPPPGPPPPYHAHAHLHHPELGPHAQQLALPQATLDDDGEMDGIGGKHCCRWIDCSALYDQQE
ELVRHIEKVHIDQRKGEDFTCFWAGCPRRYKPFNARTKLLIHMRVHSGEKPNKCTLDSATSLIQAAKNLMNAVVLTVKASTVASTKYQKV

>In-frame_GLIS3_ENST00000324333_chr9_4117768_-_CTNNA2_ENST00000541047_chr2_80874710_+_511aa
MMVQRLGLISPPASQVSTACNQISPSLQRAMNAANLNIPPSDTRSLISRESLASTTLSLTESQSASSMKQEWSQGYRALPSLSNHGSQNG
LDLGDLLSLPPGTSMSSNSVSNSLPSYLFGTESSHSPYPSPRHSSTRSHSARSKKRALSLSPLSDGIGIDFNTIIRTSPTSLVAYINGSR
ASPANLSPQPEVYGHFLGVRGSCIPQPRPVPGSQKGVLVAPGGLALPAYGEDGALEHERMQQLEHGGLQPGLVNHMVVQHGLPGPDSQSA
GLFKTERLEEFPGSTVDLPPAPPLPPLPPPPGPPPPYHAHAHLHHPELGPHAQQLALPQATLDDDGEMDGIGGKHCCRWIDCSALYDQQE
ELVRHIEKVHIDQRKGEDFTCFWAGCPRRYKPFNARTKLLIHMRVHSGEKPNKCTLDSATSLIQAAKNLMNAVVLTVKASTVASTKYQKV


* Fusion transcript sequences (only coding sequence (CDS) region).
>In-frame_GLIS3_ENST00000381971_chr9_4117768_-_CTNNA2_ENST00000361291_chr2_80874710_+_1998nt
ATGAATGGAAGATCATGCAGCATGAGTCTCCACCGGACATCGGGAACCCCACAGGGGCCTAGGATGGTCAGTGGTCATCACATTCCTGCC
ATCCGAGCCCACTCCGGGACTCCTGGCCCCTCGCCCTGTGGCAGCACATCGAGTCCCACTATGGCAAGCCTTGCTAACAACCTCCATCTC
AAGATGCCCTCAGGAGGAGGGATGGCTCCTCAGAACAACGTGGCTGAGAGCCGCATCCATCTGCCTGCCTTAAGCCCCAGGAGACAAATG
CTCACCAATGGGAAGCCGCGATTCCAGGTCACCCAGGCTGGAGGCATGTCAGGGTCACATACTTTAAAGCCAAAGCAGCAGGAGTTTGGA
AGCCCTTTTCCTCCAAATCCTGGGAAAGGGGCTCTTGGCTTTGGGCCTCAGTGCAAGTCCATTGGAAAAGGCAGCTGCAACAATCTAGTG
GTCACCAGCAGTCCCATGATGGTTCAGCGACTGGGACTCATTTCACCTCCAGCAAGCCAGGTCTCTACAGCATGCAACCAGATCAGTCCT
AGCTTACAGAGGGCAATGAATGCAGCCAACCTGAATATACCTCCTTCAGATACCAGGTCCCTTATTTCGCGTGAGTCTTTGGCGTCCACG
ACCTTGAGTCTGACGGAAAGTCAGTCGGCCTCAAGCATGAAGCAGGAGTGGTCCCAGGGCTACAGGGCCCTCCCTTCGCTCTCCAACCAC
GGCTCTCAGAATGGCCTTGATCTAGGGGATCTCCTTAGCCTTCCTCCCGGGACATCCATGTCCAGCAATAGTGTCTCTAACTCATTACCA
TCCTACCTTTTTGGCACGGAAAGTAGCCACTCTCCTTACCCTAGTCCTCGGCACTCATCCACCAGGTCCCACTCGGCCCGCTCCAAGAAG
AGAGCGCTGTCCTTGTCCCCGCTGTCCGATGGCATCGGGATAGATTTCAATACCATCATCCGCACGTCGCCCACGTCCTTGGTGGCCTAC
ATCAACGGGTCGAGGGCTTCGCCGGCCAACCTGTCCCCGCAGCCGGAGGTCTACGGGCATTTCCTGGGCGTGCGCGGCAGCTGCATTCCC
CAGCCGCGCCCGGTGCCCGGCAGCCAGAAGGGCGTGCTGGTGGCCCCTGGAGGCCTGGCGCTGCCGGCCTACGGCGAGGACGGGGCCCTG
GAGCACGAGCGCATGCAACAGCTGGAGCACGGCGGCCTGCAGCCAGGCCTGGTCAACCACATGGTGGTGCAGCATGGCCTGCCGGGCCCC
GACAGCCAGTCGGCCGGCCTGTTCAAGACCGAACGCCTGGAGGAGTTCCCGGGCAGCACCGTAGACCTACCCCCCGCGCCTCCGCTCCCT
CCTCTGCCGCCGCCCCCAGGCCCCCCACCCCCTTACCATGCCCATGCGCACCTTCACCACCCGGAGCTCGGGCCCCACGCCCAGCAGCTG
GCCTTGCCCCAGGCCACCCTGGACGACGACGGGGAGATGGACGGCATCGGGGGCAAGCATTGCTGCCGCTGGATCGACTGCAGCGCCCTG
TACGACCAGCAGGAGGAGCTCGTGCGGCACATCGAGAAGGTCCACATCGACCAGCGCAAAGGGGAGGACTTCACTTGCTTCTGGGCCGGT
TGCCCTCGAAGATACAAGCCCTTCAACGCCCGCTATAAACTGCTGATCCACATGAGAGTCCACTCTGGGGAGAAGCCCAACAAGTGTACG
CTGGACAGTGCCACATCGCTTATCCAGGCAGCTAAAAACCTGATGAATGCTGTTGTCCTCACGGTGAAAGCATCCTATGTGGCCTCAACC
AAATACCAGAAGGTCTATGGGACAGCAGCTGTCAACTCACCTGTTGTGTCTTGGAAGATGAAGGCTCCAGAGAAGAAGCCCCTTGTGAAG
AGAGAAAAGCCTGAAGAATTCCAGACACGAGTTCGACGAGGTTCTCAGAAGAAACACATTTCGCCTGTACAGGCTTTAAGTGAATTCAAA

>In-frame_GLIS3_ENST00000381971_chr9_4117768_-_CTNNA2_ENST00000540488_chr2_80874710_+_1998nt
ATGAATGGAAGATCATGCAGCATGAGTCTCCACCGGACATCGGGAACCCCACAGGGGCCTAGGATGGTCAGTGGTCATCACATTCCTGCC
ATCCGAGCCCACTCCGGGACTCCTGGCCCCTCGCCCTGTGGCAGCACATCGAGTCCCACTATGGCAAGCCTTGCTAACAACCTCCATCTC
AAGATGCCCTCAGGAGGAGGGATGGCTCCTCAGAACAACGTGGCTGAGAGCCGCATCCATCTGCCTGCCTTAAGCCCCAGGAGACAAATG
CTCACCAATGGGAAGCCGCGATTCCAGGTCACCCAGGCTGGAGGCATGTCAGGGTCACATACTTTAAAGCCAAAGCAGCAGGAGTTTGGA
AGCCCTTTTCCTCCAAATCCTGGGAAAGGGGCTCTTGGCTTTGGGCCTCAGTGCAAGTCCATTGGAAAAGGCAGCTGCAACAATCTAGTG
GTCACCAGCAGTCCCATGATGGTTCAGCGACTGGGACTCATTTCACCTCCAGCAAGCCAGGTCTCTACAGCATGCAACCAGATCAGTCCT
AGCTTACAGAGGGCAATGAATGCAGCCAACCTGAATATACCTCCTTCAGATACCAGGTCCCTTATTTCGCGTGAGTCTTTGGCGTCCACG
ACCTTGAGTCTGACGGAAAGTCAGTCGGCCTCAAGCATGAAGCAGGAGTGGTCCCAGGGCTACAGGGCCCTCCCTTCGCTCTCCAACCAC
GGCTCTCAGAATGGCCTTGATCTAGGGGATCTCCTTAGCCTTCCTCCCGGGACATCCATGTCCAGCAATAGTGTCTCTAACTCATTACCA
TCCTACCTTTTTGGCACGGAAAGTAGCCACTCTCCTTACCCTAGTCCTCGGCACTCATCCACCAGGTCCCACTCGGCCCGCTCCAAGAAG
AGAGCGCTGTCCTTGTCCCCGCTGTCCGATGGCATCGGGATAGATTTCAATACCATCATCCGCACGTCGCCCACGTCCTTGGTGGCCTAC
ATCAACGGGTCGAGGGCTTCGCCGGCCAACCTGTCCCCGCAGCCGGAGGTCTACGGGCATTTCCTGGGCGTGCGCGGCAGCTGCATTCCC
CAGCCGCGCCCGGTGCCCGGCAGCCAGAAGGGCGTGCTGGTGGCCCCTGGAGGCCTGGCGCTGCCGGCCTACGGCGAGGACGGGGCCCTG
GAGCACGAGCGCATGCAACAGCTGGAGCACGGCGGCCTGCAGCCAGGCCTGGTCAACCACATGGTGGTGCAGCATGGCCTGCCGGGCCCC
GACAGCCAGTCGGCCGGCCTGTTCAAGACCGAACGCCTGGAGGAGTTCCCGGGCAGCACCGTAGACCTACCCCCCGCGCCTCCGCTCCCT
CCTCTGCCGCCGCCCCCAGGCCCCCCACCCCCTTACCATGCCCATGCGCACCTTCACCACCCGGAGCTCGGGCCCCACGCCCAGCAGCTG
GCCTTGCCCCAGGCCACCCTGGACGACGACGGGGAGATGGACGGCATCGGGGGCAAGCATTGCTGCCGCTGGATCGACTGCAGCGCCCTG
TACGACCAGCAGGAGGAGCTCGTGCGGCACATCGAGAAGGTCCACATCGACCAGCGCAAAGGGGAGGACTTCACTTGCTTCTGGGCCGGT
TGCCCTCGAAGATACAAGCCCTTCAACGCCCGCTATAAACTGCTGATCCACATGAGAGTCCACTCTGGGGAGAAGCCCAACAAGTGTACG
CTGGACAGTGCCACATCGCTTATCCAGGCAGCTAAAAACCTGATGAATGCTGTTGTCCTCACGGTGAAAGCATCCTATGTGGCCTCAACC
AAATACCAGAAGGTCTATGGGACAGCAGCTGTCAACTCACCTGTTGTGTCTTGGAAGATGAAGGCTCCAGAGAAGAAGCCCCTTGTGAAG
AGAGAAAAGCCTGAAGAATTCCAGACACGAGTTCGACGAGGTTCTCAGAAGAAACACATTTCGCCTGTACAGGCTTTAAGTGAATTCAAA

>In-frame_GLIS3_ENST00000324333_chr9_4117768_-_CTNNA2_ENST00000466387_chr2_80874710_+_1533nt
ATGATGGTTCAGCGACTGGGACTCATTTCACCTCCAGCAAGCCAGGTCTCTACAGCATGCAACCAGATCAGTCCTAGCTTACAGAGGGCA
ATGAATGCAGCCAACCTGAATATACCTCCTTCAGATACCAGGTCCCTTATTTCGCGTGAGTCTTTGGCGTCCACGACCTTGAGTCTGACG
GAAAGTCAGTCGGCCTCAAGCATGAAGCAGGAGTGGTCCCAGGGCTACAGGGCCCTCCCTTCGCTCTCCAACCACGGCTCTCAGAATGGC
CTTGATCTAGGGGATCTCCTTAGCCTTCCTCCCGGGACATCCATGTCCAGCAATAGTGTCTCTAACTCATTACCATCCTACCTTTTTGGC
ACGGAAAGTAGCCACTCTCCTTACCCTAGTCCTCGGCACTCATCCACCAGGTCCCACTCGGCCCGCTCCAAGAAGAGAGCGCTGTCCTTG
TCCCCGCTGTCCGATGGCATCGGGATAGATTTCAATACCATCATCCGCACGTCGCCCACGTCCTTGGTGGCCTACATCAACGGGTCGAGG
GCTTCGCCGGCCAACCTGTCCCCGCAGCCGGAGGTCTACGGGCATTTCCTGGGCGTGCGCGGCAGCTGCATTCCCCAGCCGCGCCCGGTG
CCCGGCAGCCAGAAGGGCGTGCTGGTGGCCCCTGGAGGCCTGGCGCTGCCGGCCTACGGCGAGGACGGGGCCCTGGAGCACGAGCGCATG
CAACAGCTGGAGCACGGCGGCCTGCAGCCAGGCCTGGTCAACCACATGGTGGTGCAGCATGGCCTGCCGGGCCCCGACAGCCAGTCGGCC
GGCCTGTTCAAGACCGAACGCCTGGAGGAGTTCCCGGGCAGCACCGTAGACCTACCCCCCGCGCCTCCGCTCCCTCCTCTGCCGCCGCCC
CCAGGCCCCCCACCCCCTTACCATGCCCATGCGCACCTTCACCACCCGGAGCTCGGGCCCCACGCCCAGCAGCTGGCCTTGCCCCAGGCC
ACCCTGGACGACGACGGGGAGATGGACGGCATCGGGGGCAAGCATTGCTGCCGCTGGATCGACTGCAGCGCCCTGTACGACCAGCAGGAG
GAGCTCGTGCGGCACATCGAGAAGGTCCACATCGACCAGCGCAAAGGGGAGGACTTCACTTGCTTCTGGGCCGGTTGCCCTCGAAGATAC
AAGCCCTTCAACGCCCGCTATAAACTGCTGATCCACATGAGAGTCCACTCTGGGGAGAAGCCCAACAAGTGTACGCTGGACAGTGCCACA
TCGCTTATCCAGGCAGCTAAAAACCTGATGAATGCTGTTGTCCTCACGGTGAAAGCATCCTATGTGGCCTCAACCAAATACCAGAAGGTC
TATGGGACAGCAGCTGTCAACTCACCTGTTGTGTCTTGGAAGATGAAGGCTCCAGAGAAGAAGCCCCTTGTGAAGAGAGAAAAGCCTGAA
GAATTCCAGACACGAGTTCGACGAGGTTCTCAGAAGAAACACATTTCGCCTGTACAGGCTTTAAGTGAATTCAAAGCAATGGATTCCTTC

>In-frame_GLIS3_ENST00000324333_chr9_4117768_-_CTNNA2_ENST00000402739_chr2_80874710_+_1533nt
ATGATGGTTCAGCGACTGGGACTCATTTCACCTCCAGCAAGCCAGGTCTCTACAGCATGCAACCAGATCAGTCCTAGCTTACAGAGGGCA
ATGAATGCAGCCAACCTGAATATACCTCCTTCAGATACCAGGTCCCTTATTTCGCGTGAGTCTTTGGCGTCCACGACCTTGAGTCTGACG
GAAAGTCAGTCGGCCTCAAGCATGAAGCAGGAGTGGTCCCAGGGCTACAGGGCCCTCCCTTCGCTCTCCAACCACGGCTCTCAGAATGGC
CTTGATCTAGGGGATCTCCTTAGCCTTCCTCCCGGGACATCCATGTCCAGCAATAGTGTCTCTAACTCATTACCATCCTACCTTTTTGGC
ACGGAAAGTAGCCACTCTCCTTACCCTAGTCCTCGGCACTCATCCACCAGGTCCCACTCGGCCCGCTCCAAGAAGAGAGCGCTGTCCTTG
TCCCCGCTGTCCGATGGCATCGGGATAGATTTCAATACCATCATCCGCACGTCGCCCACGTCCTTGGTGGCCTACATCAACGGGTCGAGG
GCTTCGCCGGCCAACCTGTCCCCGCAGCCGGAGGTCTACGGGCATTTCCTGGGCGTGCGCGGCAGCTGCATTCCCCAGCCGCGCCCGGTG
CCCGGCAGCCAGAAGGGCGTGCTGGTGGCCCCTGGAGGCCTGGCGCTGCCGGCCTACGGCGAGGACGGGGCCCTGGAGCACGAGCGCATG
CAACAGCTGGAGCACGGCGGCCTGCAGCCAGGCCTGGTCAACCACATGGTGGTGCAGCATGGCCTGCCGGGCCCCGACAGCCAGTCGGCC
GGCCTGTTCAAGACCGAACGCCTGGAGGAGTTCCCGGGCAGCACCGTAGACCTACCCCCCGCGCCTCCGCTCCCTCCTCTGCCGCCGCCC
CCAGGCCCCCCACCCCCTTACCATGCCCATGCGCACCTTCACCACCCGGAGCTCGGGCCCCACGCCCAGCAGCTGGCCTTGCCCCAGGCC
ACCCTGGACGACGACGGGGAGATGGACGGCATCGGGGGCAAGCATTGCTGCCGCTGGATCGACTGCAGCGCCCTGTACGACCAGCAGGAG
GAGCTCGTGCGGCACATCGAGAAGGTCCACATCGACCAGCGCAAAGGGGAGGACTTCACTTGCTTCTGGGCCGGTTGCCCTCGAAGATAC
AAGCCCTTCAACGCCCGCTATAAACTGCTGATCCACATGAGAGTCCACTCTGGGGAGAAGCCCAACAAGTGTACGCTGGACAGTGCCACA
TCGCTTATCCAGGCAGCTAAAAACCTGATGAATGCTGTTGTCCTCACGGTGAAAGCATCCTATGTGGCCTCAACCAAATACCAGAAGGTC
TATGGGACAGCAGCTGTCAACTCACCTGTTGTGTCTTGGAAGATGAAGGCTCCAGAGAAGAAGCCCCTTGTGAAGAGAGAAAAGCCTGAA
GAATTCCAGACACGAGTTCGACGAGGTTCTCAGAAGAAACACATTTCGCCTGTACAGGCTTTAAGTGAATTCAAAGCAATGGATTCCTTC

>In-frame_GLIS3_ENST00000324333_chr9_4117768_-_CTNNA2_ENST00000541047_chr2_80874710_+_1533nt
ATGATGGTTCAGCGACTGGGACTCATTTCACCTCCAGCAAGCCAGGTCTCTACAGCATGCAACCAGATCAGTCCTAGCTTACAGAGGGCA
ATGAATGCAGCCAACCTGAATATACCTCCTTCAGATACCAGGTCCCTTATTTCGCGTGAGTCTTTGGCGTCCACGACCTTGAGTCTGACG
GAAAGTCAGTCGGCCTCAAGCATGAAGCAGGAGTGGTCCCAGGGCTACAGGGCCCTCCCTTCGCTCTCCAACCACGGCTCTCAGAATGGC
CTTGATCTAGGGGATCTCCTTAGCCTTCCTCCCGGGACATCCATGTCCAGCAATAGTGTCTCTAACTCATTACCATCCTACCTTTTTGGC
ACGGAAAGTAGCCACTCTCCTTACCCTAGTCCTCGGCACTCATCCACCAGGTCCCACTCGGCCCGCTCCAAGAAGAGAGCGCTGTCCTTG
TCCCCGCTGTCCGATGGCATCGGGATAGATTTCAATACCATCATCCGCACGTCGCCCACGTCCTTGGTGGCCTACATCAACGGGTCGAGG
GCTTCGCCGGCCAACCTGTCCCCGCAGCCGGAGGTCTACGGGCATTTCCTGGGCGTGCGCGGCAGCTGCATTCCCCAGCCGCGCCCGGTG
CCCGGCAGCCAGAAGGGCGTGCTGGTGGCCCCTGGAGGCCTGGCGCTGCCGGCCTACGGCGAGGACGGGGCCCTGGAGCACGAGCGCATG
CAACAGCTGGAGCACGGCGGCCTGCAGCCAGGCCTGGTCAACCACATGGTGGTGCAGCATGGCCTGCCGGGCCCCGACAGCCAGTCGGCC
GGCCTGTTCAAGACCGAACGCCTGGAGGAGTTCCCGGGCAGCACCGTAGACCTACCCCCCGCGCCTCCGCTCCCTCCTCTGCCGCCGCCC
CCAGGCCCCCCACCCCCTTACCATGCCCATGCGCACCTTCACCACCCGGAGCTCGGGCCCCACGCCCAGCAGCTGGCCTTGCCCCAGGCC
ACCCTGGACGACGACGGGGAGATGGACGGCATCGGGGGCAAGCATTGCTGCCGCTGGATCGACTGCAGCGCCCTGTACGACCAGCAGGAG
GAGCTCGTGCGGCACATCGAGAAGGTCCACATCGACCAGCGCAAAGGGGAGGACTTCACTTGCTTCTGGGCCGGTTGCCCTCGAAGATAC
AAGCCCTTCAACGCCCGCTATAAACTGCTGATCCACATGAGAGTCCACTCTGGGGAGAAGCCCAACAAGTGTACGCTGGACAGTGCCACA
TCGCTTATCCAGGCAGCTAAAAACCTGATGAATGCTGTTGTCCTCACGGTGAAAGCATCCTATGTGGCCTCAACCAAATACCAGAAGGTC
TATGGGACAGCAGCTGTCAACTCACCTGTTGTGTCTTGGAAGATGAAGGCTCCAGAGAAGAAGCCCCTTGTGAAGAGAGAAAAGCCTGAA
GAATTCCAGACACGAGTTCGACGAGGTTCTCAGAAGAAACACATTTCGCCTGTACAGGCTTTAAGTGAATTCAAAGCAATGGATTCCTTC


* Fusion transcript sequences (Full-length transcript).
>In-frame_GLIS3_ENST00000381971_chr9_4117768_-_CTNNA2_ENST00000361291_chr2_80874710_+_2592nt
CGGGACCCCCTGTACGCCGTCCGCGCCGTCCAGGGTCACACCGGCGACGGAACCCGCCGGCAGCAATTAGCCAGCATCCCGGGGTCGGCC
CCCAGAAGCATTCCCCGGCCCAGGACGAGGATGAACAGGACAGGCGAGGCACAAAGTCGCAACTGAACTTTTTAGAAACATTATTTGTGT
GTGTATGTGTGTAGCAGGGGAGAATGAGCTGATGCCGAGGGTCCAGCCACCCCGCCTCTGCCTCCTCCTCCCCCTGCCGCCGCTGCCCTC
GCAGACGCGCGCGCACACACGGCACTTGGGCCGGGTTTCCGCGCTCCGTCCCCCCGTTTGGATGGGGGTTTTCATTTCCGAAGGAGGCAC
AGCCCGCGGAGCGCTCTGAAGGGCTGGAGCCCCAAGTTACTCCTCGCCAGCGCCGGCCGCCCGCTGTCACTCGCGCTGGCCGGCCGGGGG
AAGGGACCCGCACGCCGGGCTTTGTTGTGGAAATCCCGGTTACCTGGCTTATAACCCACACCATGGATAACTTATTGGACTTTGCCTGAA
AGGAGTCATTAGTGACATTGGATATTTGACCGTCTTGGCCACAGGTTTTTCAGAATGAATGGAAGATCATGCAGCATGAGTCTCCACCGG
ACATCGGGAACCCCACAGGGGCCTAGGATGGTCAGTGGTCATCACATTCCTGCCATCCGAGCCCACTCCGGGACTCCTGGCCCCTCGCCC
TGTGGCAGCACATCGAGTCCCACTATGGCAAGCCTTGCTAACAACCTCCATCTCAAGATGCCCTCAGGAGGAGGGATGGCTCCTCAGAAC
AACGTGGCTGAGAGCCGCATCCATCTGCCTGCCTTAAGCCCCAGGAGACAAATGCTCACCAATGGGAAGCCGCGATTCCAGGTCACCCAG
GCTGGAGGCATGTCAGGGTCACATACTTTAAAGCCAAAGCAGCAGGAGTTTGGAAGCCCTTTTCCTCCAAATCCTGGGAAAGGGGCTCTT
GGCTTTGGGCCTCAGTGCAAGTCCATTGGAAAAGGCAGCTGCAACAATCTAGTGGTCACCAGCAGTCCCATGATGGTTCAGCGACTGGGA
CTCATTTCACCTCCAGCAAGCCAGGTCTCTACAGCATGCAACCAGATCAGTCCTAGCTTACAGAGGGCAATGAATGCAGCCAACCTGAAT
ATACCTCCTTCAGATACCAGGTCCCTTATTTCGCGTGAGTCTTTGGCGTCCACGACCTTGAGTCTGACGGAAAGTCAGTCGGCCTCAAGC
ATGAAGCAGGAGTGGTCCCAGGGCTACAGGGCCCTCCCTTCGCTCTCCAACCACGGCTCTCAGAATGGCCTTGATCTAGGGGATCTCCTT
AGCCTTCCTCCCGGGACATCCATGTCCAGCAATAGTGTCTCTAACTCATTACCATCCTACCTTTTTGGCACGGAAAGTAGCCACTCTCCT
TACCCTAGTCCTCGGCACTCATCCACCAGGTCCCACTCGGCCCGCTCCAAGAAGAGAGCGCTGTCCTTGTCCCCGCTGTCCGATGGCATC
GGGATAGATTTCAATACCATCATCCGCACGTCGCCCACGTCCTTGGTGGCCTACATCAACGGGTCGAGGGCTTCGCCGGCCAACCTGTCC
CCGCAGCCGGAGGTCTACGGGCATTTCCTGGGCGTGCGCGGCAGCTGCATTCCCCAGCCGCGCCCGGTGCCCGGCAGCCAGAAGGGCGTG
CTGGTGGCCCCTGGAGGCCTGGCGCTGCCGGCCTACGGCGAGGACGGGGCCCTGGAGCACGAGCGCATGCAACAGCTGGAGCACGGCGGC
CTGCAGCCAGGCCTGGTCAACCACATGGTGGTGCAGCATGGCCTGCCGGGCCCCGACAGCCAGTCGGCCGGCCTGTTCAAGACCGAACGC
CTGGAGGAGTTCCCGGGCAGCACCGTAGACCTACCCCCCGCGCCTCCGCTCCCTCCTCTGCCGCCGCCCCCAGGCCCCCCACCCCCTTAC
CATGCCCATGCGCACCTTCACCACCCGGAGCTCGGGCCCCACGCCCAGCAGCTGGCCTTGCCCCAGGCCACCCTGGACGACGACGGGGAG
ATGGACGGCATCGGGGGCAAGCATTGCTGCCGCTGGATCGACTGCAGCGCCCTGTACGACCAGCAGGAGGAGCTCGTGCGGCACATCGAG
AAGGTCCACATCGACCAGCGCAAAGGGGAGGACTTCACTTGCTTCTGGGCCGGTTGCCCTCGAAGATACAAGCCCTTCAACGCCCGCTAT
AAACTGCTGATCCACATGAGAGTCCACTCTGGGGAGAAGCCCAACAAGTGTACGCTGGACAGTGCCACATCGCTTATCCAGGCAGCTAAA
AACCTGATGAATGCTGTTGTCCTCACGGTGAAAGCATCCTATGTGGCCTCAACCAAATACCAGAAGGTCTATGGGACAGCAGCTGTCAAC
TCACCTGTTGTGTCTTGGAAGATGAAGGCTCCAGAGAAGAAGCCCCTTGTGAAGAGAGAAAAGCCTGAAGAATTCCAGACACGAGTTCGA

>In-frame_GLIS3_ENST00000381971_chr9_4117768_-_CTNNA2_ENST00000540488_chr2_80874710_+_2592nt
CGGGACCCCCTGTACGCCGTCCGCGCCGTCCAGGGTCACACCGGCGACGGAACCCGCCGGCAGCAATTAGCCAGCATCCCGGGGTCGGCC
CCCAGAAGCATTCCCCGGCCCAGGACGAGGATGAACAGGACAGGCGAGGCACAAAGTCGCAACTGAACTTTTTAGAAACATTATTTGTGT
GTGTATGTGTGTAGCAGGGGAGAATGAGCTGATGCCGAGGGTCCAGCCACCCCGCCTCTGCCTCCTCCTCCCCCTGCCGCCGCTGCCCTC
GCAGACGCGCGCGCACACACGGCACTTGGGCCGGGTTTCCGCGCTCCGTCCCCCCGTTTGGATGGGGGTTTTCATTTCCGAAGGAGGCAC
AGCCCGCGGAGCGCTCTGAAGGGCTGGAGCCCCAAGTTACTCCTCGCCAGCGCCGGCCGCCCGCTGTCACTCGCGCTGGCCGGCCGGGGG
AAGGGACCCGCACGCCGGGCTTTGTTGTGGAAATCCCGGTTACCTGGCTTATAACCCACACCATGGATAACTTATTGGACTTTGCCTGAA
AGGAGTCATTAGTGACATTGGATATTTGACCGTCTTGGCCACAGGTTTTTCAGAATGAATGGAAGATCATGCAGCATGAGTCTCCACCGG
ACATCGGGAACCCCACAGGGGCCTAGGATGGTCAGTGGTCATCACATTCCTGCCATCCGAGCCCACTCCGGGACTCCTGGCCCCTCGCCC
TGTGGCAGCACATCGAGTCCCACTATGGCAAGCCTTGCTAACAACCTCCATCTCAAGATGCCCTCAGGAGGAGGGATGGCTCCTCAGAAC
AACGTGGCTGAGAGCCGCATCCATCTGCCTGCCTTAAGCCCCAGGAGACAAATGCTCACCAATGGGAAGCCGCGATTCCAGGTCACCCAG
GCTGGAGGCATGTCAGGGTCACATACTTTAAAGCCAAAGCAGCAGGAGTTTGGAAGCCCTTTTCCTCCAAATCCTGGGAAAGGGGCTCTT
GGCTTTGGGCCTCAGTGCAAGTCCATTGGAAAAGGCAGCTGCAACAATCTAGTGGTCACCAGCAGTCCCATGATGGTTCAGCGACTGGGA
CTCATTTCACCTCCAGCAAGCCAGGTCTCTACAGCATGCAACCAGATCAGTCCTAGCTTACAGAGGGCAATGAATGCAGCCAACCTGAAT
ATACCTCCTTCAGATACCAGGTCCCTTATTTCGCGTGAGTCTTTGGCGTCCACGACCTTGAGTCTGACGGAAAGTCAGTCGGCCTCAAGC
ATGAAGCAGGAGTGGTCCCAGGGCTACAGGGCCCTCCCTTCGCTCTCCAACCACGGCTCTCAGAATGGCCTTGATCTAGGGGATCTCCTT
AGCCTTCCTCCCGGGACATCCATGTCCAGCAATAGTGTCTCTAACTCATTACCATCCTACCTTTTTGGCACGGAAAGTAGCCACTCTCCT
TACCCTAGTCCTCGGCACTCATCCACCAGGTCCCACTCGGCCCGCTCCAAGAAGAGAGCGCTGTCCTTGTCCCCGCTGTCCGATGGCATC
GGGATAGATTTCAATACCATCATCCGCACGTCGCCCACGTCCTTGGTGGCCTACATCAACGGGTCGAGGGCTTCGCCGGCCAACCTGTCC
CCGCAGCCGGAGGTCTACGGGCATTTCCTGGGCGTGCGCGGCAGCTGCATTCCCCAGCCGCGCCCGGTGCCCGGCAGCCAGAAGGGCGTG
CTGGTGGCCCCTGGAGGCCTGGCGCTGCCGGCCTACGGCGAGGACGGGGCCCTGGAGCACGAGCGCATGCAACAGCTGGAGCACGGCGGC
CTGCAGCCAGGCCTGGTCAACCACATGGTGGTGCAGCATGGCCTGCCGGGCCCCGACAGCCAGTCGGCCGGCCTGTTCAAGACCGAACGC
CTGGAGGAGTTCCCGGGCAGCACCGTAGACCTACCCCCCGCGCCTCCGCTCCCTCCTCTGCCGCCGCCCCCAGGCCCCCCACCCCCTTAC
CATGCCCATGCGCACCTTCACCACCCGGAGCTCGGGCCCCACGCCCAGCAGCTGGCCTTGCCCCAGGCCACCCTGGACGACGACGGGGAG
ATGGACGGCATCGGGGGCAAGCATTGCTGCCGCTGGATCGACTGCAGCGCCCTGTACGACCAGCAGGAGGAGCTCGTGCGGCACATCGAG
AAGGTCCACATCGACCAGCGCAAAGGGGAGGACTTCACTTGCTTCTGGGCCGGTTGCCCTCGAAGATACAAGCCCTTCAACGCCCGCTAT
AAACTGCTGATCCACATGAGAGTCCACTCTGGGGAGAAGCCCAACAAGTGTACGCTGGACAGTGCCACATCGCTTATCCAGGCAGCTAAA
AACCTGATGAATGCTGTTGTCCTCACGGTGAAAGCATCCTATGTGGCCTCAACCAAATACCAGAAGGTCTATGGGACAGCAGCTGTCAAC
TCACCTGTTGTGTCTTGGAAGATGAAGGCTCCAGAGAAGAAGCCCCTTGTGAAGAGAGAAAAGCCTGAAGAATTCCAGACACGAGTTCGA

>In-frame_GLIS3_ENST00000324333_chr9_4117768_-_CTNNA2_ENST00000466387_chr2_80874710_+_2634nt
ATCCTTTATGGTTGAAGGGTGTTGGAGGAAGCAGAGTTTTCATCAGCTGCTGAAGTGGCAACTAATAGAGGTTTGAATGGCCGTAGAAAA
ATATTGTGTTACTTGTTTGTTGTCTAGGGGCTCTTGGCTTTGGGCCTCAGTGCAAGTCCATTGGAAAAGGCAGCTGCAACAATCTAGTGG
TCACCAGCAGTCCCATGATGGTTCAGCGACTGGGACTCATTTCACCTCCAGCAAGCCAGGTCTCTACAGCATGCAACCAGATCAGTCCTA
GCTTACAGAGGGCAATGAATGCAGCCAACCTGAATATACCTCCTTCAGATACCAGGTCCCTTATTTCGCGTGAGTCTTTGGCGTCCACGA
CCTTGAGTCTGACGGAAAGTCAGTCGGCCTCAAGCATGAAGCAGGAGTGGTCCCAGGGCTACAGGGCCCTCCCTTCGCTCTCCAACCACG
GCTCTCAGAATGGCCTTGATCTAGGGGATCTCCTTAGCCTTCCTCCCGGGACATCCATGTCCAGCAATAGTGTCTCTAACTCATTACCAT
CCTACCTTTTTGGCACGGAAAGTAGCCACTCTCCTTACCCTAGTCCTCGGCACTCATCCACCAGGTCCCACTCGGCCCGCTCCAAGAAGA
GAGCGCTGTCCTTGTCCCCGCTGTCCGATGGCATCGGGATAGATTTCAATACCATCATCCGCACGTCGCCCACGTCCTTGGTGGCCTACA
TCAACGGGTCGAGGGCTTCGCCGGCCAACCTGTCCCCGCAGCCGGAGGTCTACGGGCATTTCCTGGGCGTGCGCGGCAGCTGCATTCCCC
AGCCGCGCCCGGTGCCCGGCAGCCAGAAGGGCGTGCTGGTGGCCCCTGGAGGCCTGGCGCTGCCGGCCTACGGCGAGGACGGGGCCCTGG
AGCACGAGCGCATGCAACAGCTGGAGCACGGCGGCCTGCAGCCAGGCCTGGTCAACCACATGGTGGTGCAGCATGGCCTGCCGGGCCCCG
ACAGCCAGTCGGCCGGCCTGTTCAAGACCGAACGCCTGGAGGAGTTCCCGGGCAGCACCGTAGACCTACCCCCCGCGCCTCCGCTCCCTC
CTCTGCCGCCGCCCCCAGGCCCCCCACCCCCTTACCATGCCCATGCGCACCTTCACCACCCGGAGCTCGGGCCCCACGCCCAGCAGCTGG
CCTTGCCCCAGGCCACCCTGGACGACGACGGGGAGATGGACGGCATCGGGGGCAAGCATTGCTGCCGCTGGATCGACTGCAGCGCCCTGT
ACGACCAGCAGGAGGAGCTCGTGCGGCACATCGAGAAGGTCCACATCGACCAGCGCAAAGGGGAGGACTTCACTTGCTTCTGGGCCGGTT
GCCCTCGAAGATACAAGCCCTTCAACGCCCGCTATAAACTGCTGATCCACATGAGAGTCCACTCTGGGGAGAAGCCCAACAAGTGTACGC
TGGACAGTGCCACATCGCTTATCCAGGCAGCTAAAAACCTGATGAATGCTGTTGTCCTCACGGTGAAAGCATCCTATGTGGCCTCAACCA
AATACCAGAAGGTCTATGGGACAGCAGCTGTCAACTCACCTGTTGTGTCTTGGAAGATGAAGGCTCCAGAGAAGAAGCCCCTTGTGAAGA
GAGAAAAGCCTGAAGAATTCCAGACACGAGTTCGACGAGGTTCTCAGAAGAAACACATTTCGCCTGTACAGGCTTTAAGTGAATTCAAAG
CAATGGATTCCTTCTAGGACGATAGGTTTTAACAAGAAAGCTTTTTCTTTCTTTTCTTTCTTTCTTTTTCTTTTTAATTCCATTTTTGTA
TGCATACCTGCCAGCTCGTATGCCTCTGGCATGGGGAAATTAAGGGAACAGTGTCTGTTTGCATGTAAGATGAGATGAGATCAATACTAC
TGATCCATCTGTAGCCTGGGAAGGAGACAGGACATTCCTGTACTAAGGTGGCACAGAGCTGTCCTTTGCAACATTCTCATAAAATTGGGC
ACAGAGTTCGCATTGGCGCAATATTTATGGGAGTGGGAGGGATGGGGAAAATAAACTTAACTCTACAAAAGCAAACTCTAATGCATGCAA
GAATCATTAGGTTGGCAGGTATATGCATAAGTGAAAAATCTGGAAGTGTAATGGTAGAACATAAAACTTGTATTGCTTCTGTTTCAGTGC
AAAAATGTACTAGCCAATACGCTTAAGTGTGTGGCCCATGAATTGAACAATTTAACCTTGAAGTCTATATCCGTGATATTATGTCGATTT
TTAACTGAGGGGAAATTAACTAGTCCAGCCTAAAATGCTTCTTTTAATCTGCATTCTGTTTCCTCTTCTAGTTGTGCCATTACTAGTGAT
CATGTTTTTTTCCCCCCTTTAATGAAAACAATAAACATCTATTTGAGACAATTAAAATCCTTCTGGGGGCACTGGAAGCACAATACGGTG
ACCAATCTTGCTTTCATTTTTTTTTCTTTTTAATTTGAACCATGATTTTGCTAGAAATAGAAGGCCCAGTGGTGGAATATTAGAGGGAAG
GAAACTGACAACGTGTGAAAGTTAGAGGCAAATACATAGGTGTAGCTTGGAGTGCTGGTATCTAATATACCATTGTATTCACTAACTAAC

>In-frame_GLIS3_ENST00000324333_chr9_4117768_-_CTNNA2_ENST00000402739_chr2_80874710_+_2544nt
ATCCTTTATGGTTGAAGGGTGTTGGAGGAAGCAGAGTTTTCATCAGCTGCTGAAGTGGCAACTAATAGAGGTTTGAATGGCCGTAGAAAA
ATATTGTGTTACTTGTTTGTTGTCTAGGGGCTCTTGGCTTTGGGCCTCAGTGCAAGTCCATTGGAAAAGGCAGCTGCAACAATCTAGTGG
TCACCAGCAGTCCCATGATGGTTCAGCGACTGGGACTCATTTCACCTCCAGCAAGCCAGGTCTCTACAGCATGCAACCAGATCAGTCCTA
GCTTACAGAGGGCAATGAATGCAGCCAACCTGAATATACCTCCTTCAGATACCAGGTCCCTTATTTCGCGTGAGTCTTTGGCGTCCACGA
CCTTGAGTCTGACGGAAAGTCAGTCGGCCTCAAGCATGAAGCAGGAGTGGTCCCAGGGCTACAGGGCCCTCCCTTCGCTCTCCAACCACG
GCTCTCAGAATGGCCTTGATCTAGGGGATCTCCTTAGCCTTCCTCCCGGGACATCCATGTCCAGCAATAGTGTCTCTAACTCATTACCAT
CCTACCTTTTTGGCACGGAAAGTAGCCACTCTCCTTACCCTAGTCCTCGGCACTCATCCACCAGGTCCCACTCGGCCCGCTCCAAGAAGA
GAGCGCTGTCCTTGTCCCCGCTGTCCGATGGCATCGGGATAGATTTCAATACCATCATCCGCACGTCGCCCACGTCCTTGGTGGCCTACA
TCAACGGGTCGAGGGCTTCGCCGGCCAACCTGTCCCCGCAGCCGGAGGTCTACGGGCATTTCCTGGGCGTGCGCGGCAGCTGCATTCCCC
AGCCGCGCCCGGTGCCCGGCAGCCAGAAGGGCGTGCTGGTGGCCCCTGGAGGCCTGGCGCTGCCGGCCTACGGCGAGGACGGGGCCCTGG
AGCACGAGCGCATGCAACAGCTGGAGCACGGCGGCCTGCAGCCAGGCCTGGTCAACCACATGGTGGTGCAGCATGGCCTGCCGGGCCCCG
ACAGCCAGTCGGCCGGCCTGTTCAAGACCGAACGCCTGGAGGAGTTCCCGGGCAGCACCGTAGACCTACCCCCCGCGCCTCCGCTCCCTC
CTCTGCCGCCGCCCCCAGGCCCCCCACCCCCTTACCATGCCCATGCGCACCTTCACCACCCGGAGCTCGGGCCCCACGCCCAGCAGCTGG
CCTTGCCCCAGGCCACCCTGGACGACGACGGGGAGATGGACGGCATCGGGGGCAAGCATTGCTGCCGCTGGATCGACTGCAGCGCCCTGT
ACGACCAGCAGGAGGAGCTCGTGCGGCACATCGAGAAGGTCCACATCGACCAGCGCAAAGGGGAGGACTTCACTTGCTTCTGGGCCGGTT
GCCCTCGAAGATACAAGCCCTTCAACGCCCGCTATAAACTGCTGATCCACATGAGAGTCCACTCTGGGGAGAAGCCCAACAAGTGTACGC
TGGACAGTGCCACATCGCTTATCCAGGCAGCTAAAAACCTGATGAATGCTGTTGTCCTCACGGTGAAAGCATCCTATGTGGCCTCAACCA
AATACCAGAAGGTCTATGGGACAGCAGCTGTCAACTCACCTGTTGTGTCTTGGAAGATGAAGGCTCCAGAGAAGAAGCCCCTTGTGAAGA
GAGAAAAGCCTGAAGAATTCCAGACACGAGTTCGACGAGGTTCTCAGAAGAAACACATTTCGCCTGTACAGGCTTTAAGTGAATTCAAAG
CAATGGATTCCTTCTAGGACGATAGGTTTTAACAAGAAAGCTTTTTCTTTCTTTTCTTTCTTTCTTTTTCTTTTTAATTCCATTTTTGTA
TGCATACCTGCCAGCTCGTATGCCTCTGGCATGGGGAAATTAAGGGAACAGTGTCTGTTTGCATGTAAGATGAGATGAGATCAATACTAC
TGATCCATCTGTAGCCTGGGAAGGAGACAGGACATTCCTGTACTAAGGTGGCACAGAGCTGTCCTTTGCAACATTCTCATAAAATTGGGC
ACAGAGTTCGCATTGGCGCAATATTTATGGGAGTGGGAGGGATGGGGAAAATAAACTTAACTCTACAAAAGCAAACTCTAATGCATGCAA
GAATCATTAGGTTGGCAGGTATATGCATAAGTGAAAAATCTGGAAGTGTAATGGTAGAACATAAAACTTGTATTGCTTCTGTTTCAGTGC
AAAAATGTACTAGCCAATACGCTTAAGTGTGTGGCCCATGAATTGAACAATTTAACCTTGAAGTCTATATCCGTGATATTATGTCGATTT
TTAACTGAGGGGAAATTAACTAGTCCAGCCTAAAATGCTTCTTTTAATCTGCATTCTGTTTCCTCTTCTAGTTGTGCCATTACTAGTGAT
CATGTTTTTTTCCCCCCTTTAATGAAAACAATAAACATCTATTTGAGACAATTAAAATCCTTCTGGGGGCACTGGAAGCACAATACGGTG
ACCAATCTTGCTTTCATTTTTTTTTCTTTTTAATTTGAACCATGATTTTGCTAGAAATAGAAGGCCCAGTGGTGGAATATTAGAGGGAAG

>In-frame_GLIS3_ENST00000324333_chr9_4117768_-_CTNNA2_ENST00000541047_chr2_80874710_+_2634nt
ATCCTTTATGGTTGAAGGGTGTTGGAGGAAGCAGAGTTTTCATCAGCTGCTGAAGTGGCAACTAATAGAGGTTTGAATGGCCGTAGAAAA
ATATTGTGTTACTTGTTTGTTGTCTAGGGGCTCTTGGCTTTGGGCCTCAGTGCAAGTCCATTGGAAAAGGCAGCTGCAACAATCTAGTGG
TCACCAGCAGTCCCATGATGGTTCAGCGACTGGGACTCATTTCACCTCCAGCAAGCCAGGTCTCTACAGCATGCAACCAGATCAGTCCTA
GCTTACAGAGGGCAATGAATGCAGCCAACCTGAATATACCTCCTTCAGATACCAGGTCCCTTATTTCGCGTGAGTCTTTGGCGTCCACGA
CCTTGAGTCTGACGGAAAGTCAGTCGGCCTCAAGCATGAAGCAGGAGTGGTCCCAGGGCTACAGGGCCCTCCCTTCGCTCTCCAACCACG
GCTCTCAGAATGGCCTTGATCTAGGGGATCTCCTTAGCCTTCCTCCCGGGACATCCATGTCCAGCAATAGTGTCTCTAACTCATTACCAT
CCTACCTTTTTGGCACGGAAAGTAGCCACTCTCCTTACCCTAGTCCTCGGCACTCATCCACCAGGTCCCACTCGGCCCGCTCCAAGAAGA
GAGCGCTGTCCTTGTCCCCGCTGTCCGATGGCATCGGGATAGATTTCAATACCATCATCCGCACGTCGCCCACGTCCTTGGTGGCCTACA
TCAACGGGTCGAGGGCTTCGCCGGCCAACCTGTCCCCGCAGCCGGAGGTCTACGGGCATTTCCTGGGCGTGCGCGGCAGCTGCATTCCCC
AGCCGCGCCCGGTGCCCGGCAGCCAGAAGGGCGTGCTGGTGGCCCCTGGAGGCCTGGCGCTGCCGGCCTACGGCGAGGACGGGGCCCTGG
AGCACGAGCGCATGCAACAGCTGGAGCACGGCGGCCTGCAGCCAGGCCTGGTCAACCACATGGTGGTGCAGCATGGCCTGCCGGGCCCCG
ACAGCCAGTCGGCCGGCCTGTTCAAGACCGAACGCCTGGAGGAGTTCCCGGGCAGCACCGTAGACCTACCCCCCGCGCCTCCGCTCCCTC
CTCTGCCGCCGCCCCCAGGCCCCCCACCCCCTTACCATGCCCATGCGCACCTTCACCACCCGGAGCTCGGGCCCCACGCCCAGCAGCTGG
CCTTGCCCCAGGCCACCCTGGACGACGACGGGGAGATGGACGGCATCGGGGGCAAGCATTGCTGCCGCTGGATCGACTGCAGCGCCCTGT
ACGACCAGCAGGAGGAGCTCGTGCGGCACATCGAGAAGGTCCACATCGACCAGCGCAAAGGGGAGGACTTCACTTGCTTCTGGGCCGGTT
GCCCTCGAAGATACAAGCCCTTCAACGCCCGCTATAAACTGCTGATCCACATGAGAGTCCACTCTGGGGAGAAGCCCAACAAGTGTACGC
TGGACAGTGCCACATCGCTTATCCAGGCAGCTAAAAACCTGATGAATGCTGTTGTCCTCACGGTGAAAGCATCCTATGTGGCCTCAACCA
AATACCAGAAGGTCTATGGGACAGCAGCTGTCAACTCACCTGTTGTGTCTTGGAAGATGAAGGCTCCAGAGAAGAAGCCCCTTGTGAAGA
GAGAAAAGCCTGAAGAATTCCAGACACGAGTTCGACGAGGTTCTCAGAAGAAACACATTTCGCCTGTACAGGCTTTAAGTGAATTCAAAG
CAATGGATTCCTTCTAGGACGATAGGTTTTAACAAGAAAGCTTTTTCTTTCTTTTCTTTCTTTCTTTTTCTTTTTAATTCCATTTTTGTA
TGCATACCTGCCAGCTCGTATGCCTCTGGCATGGGGAAATTAAGGGAACAGTGTCTGTTTGCATGTAAGATGAGATGAGATCAATACTAC
TGATCCATCTGTAGCCTGGGAAGGAGACAGGACATTCCTGTACTAAGGTGGCACAGAGCTGTCCTTTGCAACATTCTCATAAAATTGGGC
ACAGAGTTCGCATTGGCGCAATATTTATGGGAGTGGGAGGGATGGGGAAAATAAACTTAACTCTACAAAAGCAAACTCTAATGCATGCAA
GAATCATTAGGTTGGCAGGTATATGCATAAGTGAAAAATCTGGAAGTGTAATGGTAGAACATAAAACTTGTATTGCTTCTGTTTCAGTGC
AAAAATGTACTAGCCAATACGCTTAAGTGTGTGGCCCATGAATTGAACAATTTAACCTTGAAGTCTATATCCGTGATATTATGTCGATTT
TTAACTGAGGGGAAATTAACTAGTCCAGCCTAAAATGCTTCTTTTAATCTGCATTCTGTTTCCTCTTCTAGTTGTGCCATTACTAGTGAT
CATGTTTTTTTCCCCCCTTTAATGAAAACAATAAACATCTATTTGAGACAATTAAAATCCTTCTGGGGGCACTGGAAGCACAATACGGTG
ACCAATCTTGCTTTCATTTTTTTTTCTTTTTAATTTGAACCATGATTTTGCTAGAAATAGAAGGCCCAGTGGTGGAATATTAGAGGGAAG
GAAACTGACAACGTGTGAAAGTTAGAGGCAAATACATAGGTGTAGCTTGGAGTGCTGGTATCTAATATACCATTGTATTCACTAACTAAC


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FusionGenePPI for GLIS3_CTNNA2


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page

.

check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors
GLIS3SUFU, SOX2, CLNK, ITCH, PRMT5, DNAJA1, SMURF2, NEDD4CTNNA2PAN2, PPP2R1A, FBXW11, CD27, UTP3, SAPCD1, CTNNB1, JUP, NTRK1, SDHAF2, GAN, MCM2, EGFR, CDH1, CDH8, CDH5, CTNNBIP1, DUSP22, FBXL5, CIR1, G3BP1, UBE2A, TES


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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RelatedDrugs for GLIS3_CTNNA2


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for GLIS3_CTNNA2


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneGLIS3C0011854Diabetes Mellitus, Insulin-Dependent1CTD_human
HgeneGLIS3C0011860Diabetes Mellitus, Non-Insulin-Dependent1CTD_human
HgeneGLIS3C0017605Angle Closure Glaucoma1CTD_human
TgeneCTNNA2C0001973Alcoholic Intoxication, Chronic1PSYGENET
TgeneCTNNA2C0036341Schizophrenia1PSYGENET
TgeneCTNNA2C0038356Stomach Neoplasms1CTD_human