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Fusion gene ID: 14684 |
FusionGeneSummary for GLB1_CMTM7 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: GLB1_CMTM7 | Fusion gene ID: 14684 | Hgene | Tgene | Gene symbol | GLB1 | CMTM7 | Gene ID | 2720 | 112616 |
| Gene name | galactosidase beta 1 | CKLF like MARVEL transmembrane domain containing 7 | |
| Synonyms | EBP|ELNR1|MPS4B | CKLFSF7 | |
| Cytomap | 3p22.3 | 3p22.3 | |
| Type of gene | protein-coding | protein-coding | |
| Description | beta-galactosidaseacid beta-galactosidaseelastin receptor 1, 67kDalactase | CKLF-like MARVEL transmembrane domain-containing protein 7chemokine-like factor super family 7chemokine-like factor super family member 7 variant 2chemokine-like factor superfamily 7chemokine-like factor superfamily member 7 | |
| Modification date | 20180523 | 20180523 | |
| UniProtAcc | P16278 | Q96FZ5 | |
| Ensembl transtripts involved in fusion gene | ENST00000307363, ENST00000399402, ENST00000445488, ENST00000307377, ENST00000497796, | ENST00000334983, ENST00000349718, | |
| Fusion gene scores | * DoF score | 4 X 4 X 4=64 | 3 X 2 X 3=18 |
| # samples | 5 | 3 | |
| ** MAII score | log2(5/64*10)=-0.356143810225275 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(3/18*10)=0.736965594166206 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
| Context | PubMed: GLB1 [Title/Abstract] AND CMTM7 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | GLB1 | GO:0044262 | cellular carbohydrate metabolic process | 11927518 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChiTaRS3.1 | XX000016 | GLB1 | chr3 | 33055546 | - | CMTM7 | chr3 | 32483330 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000307363 | ENST00000334983 | GLB1 | chr3 | 33055546 | - | CMTM7 | chr3 | 32483330 | + |
| In-frame | ENST00000307363 | ENST00000349718 | GLB1 | chr3 | 33055546 | - | CMTM7 | chr3 | 32483330 | + |
| Frame-shift | ENST00000399402 | ENST00000334983 | GLB1 | chr3 | 33055546 | - | CMTM7 | chr3 | 32483330 | + |
| Frame-shift | ENST00000399402 | ENST00000349718 | GLB1 | chr3 | 33055546 | - | CMTM7 | chr3 | 32483330 | + |
| In-frame | ENST00000445488 | ENST00000334983 | GLB1 | chr3 | 33055546 | - | CMTM7 | chr3 | 32483330 | + |
| In-frame | ENST00000445488 | ENST00000349718 | GLB1 | chr3 | 33055546 | - | CMTM7 | chr3 | 32483330 | + |
| In-frame | ENST00000307377 | ENST00000334983 | GLB1 | chr3 | 33055546 | - | CMTM7 | chr3 | 32483330 | + |
| In-frame | ENST00000307377 | ENST00000349718 | GLB1 | chr3 | 33055546 | - | CMTM7 | chr3 | 32483330 | + |
| intron-3CDS | ENST00000497796 | ENST00000334983 | GLB1 | chr3 | 33055546 | - | CMTM7 | chr3 | 32483330 | + |
| intron-3CDS | ENST00000497796 | ENST00000349718 | GLB1 | chr3 | 33055546 | - | CMTM7 | chr3 | 32483330 | + |
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FusionProtFeatures for GLB1_CMTM7 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| GLB1 | CMTM7 |
| Isoform 1: Cleaves beta-linked terminal galactosylresidues from gangliosides, glycoproteins, and glycosaminoglycans.{ECO:0000269|PubMed:15714521, ECO:0000269|PubMed:19472408,ECO:0000269|PubMed:2511208, ECO:0000269|PubMed:25936995,ECO:0000269|PubMed:8200356}. Isoform 2: Has no beta-galactosidase catalytic activity,but plays functional roles in the formation of extracellularelastic fibers (elastogenesis) and in the development ofconnective tissue. Seems to be identical to the elastin-bindingprotein (EBP), a major component of the non-integrin cell surfacereceptor expressed on fibroblasts, smooth muscle cells,chondroblasts, leukocytes, and certain cancer cell types. Inelastin producing cells, associates with tropoelastinintracellularly and functions as a recycling molecular chaperonewhich facilitates the secretions of tropoelastin and its assemblyinto elastic fibers. {ECO:0000269|PubMed:10841810,ECO:0000269|PubMed:8922281}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | >CMTM7 | chr3:33055546 | chr3:32483330 | ENST00000334983 | + | 0 | 5 | 110_130 | 53 | 176 | Transmembrane | Helical |
| Tgene | >CMTM7 | chr3:33055546 | chr3:32483330 | ENST00000334983 | + | 0 | 5 | 140_160 | 53 | 176 | Transmembrane | Helical |
| Tgene | >CMTM7 | chr3:33055546 | chr3:32483330 | ENST00000334983 | + | 0 | 5 | 77_97 | 53 | 176 | Transmembrane | Helical |
| Tgene | >CMTM7 | chr3:33055546 | chr3:32483330 | ENST00000349718 | + | 0 | 4 | 110_130 | 53 | 143 | Transmembrane | Helical |
| Tgene | >CMTM7 | chr3:33055546 | chr3:32483330 | ENST00000349718 | + | 0 | 4 | 140_160 | 53 | 143 | Transmembrane | Helical |
| Tgene | >CMTM7 | chr3:33055546 | chr3:32483330 | ENST00000349718 | + | 0 | 4 | 77_97 | 53 | 143 | Transmembrane | Helical |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | CMTM7 | chr3:33055546 | chr3:32483330 | ENST00000334983 | + | 0 | 5 | 40_166 | 53 | 176 | Domain | MARVEL |
| Tgene | CMTM7 | chr3:33055546 | chr3:32483330 | ENST00000349718 | + | 0 | 4 | 40_166 | 53 | 143 | Domain | MARVEL |
| Tgene | CMTM7 | chr3:33055546 | chr3:32483330 | ENST00000334983 | + | 0 | 5 | 43_63 | 53 | 176 | Transmembrane | Helical |
| Tgene | CMTM7 | chr3:33055546 | chr3:32483330 | ENST00000349718 | + | 0 | 4 | 43_63 | 53 | 143 | Transmembrane | Helical |
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FusionGeneSequence for GLB1_CMTM7 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_GLB1_ENST00000307363_chr3_33055546_-_CMTM7_ENST00000334983_chr3_32483330_+_123aa VTLLIAFICVRSSLWTNYSAYSYFEVVTICDLIMILAFYLVHLFRFYRVLTCISWPLSELLHYLIGTLLLLIASIVAASKSYNQSGLVAG >In-frame_GLB1_ENST00000307363_chr3_33055546_-_CMTM7_ENST00000349718_chr3_32483330_+_90aa VTLLIAFICVRSSLWTNYSAYSYFEVVTICDLIMILAFYLVHLFRFYRVLTCISWPLSIFGFMATFLCMASIWLSYKISCVTQSTDAAVX >In-frame_GLB1_ENST00000445488_chr3_33055546_-_CMTM7_ENST00000334983_chr3_32483330_+_123aa VTLLIAFICVRSSLWTNYSAYSYFEVVTICDLIMILAFYLVHLFRFYRVLTCISWPLSELLHYLIGTLLLLIASIVAASKSYNQSGLVAG >In-frame_GLB1_ENST00000445488_chr3_33055546_-_CMTM7_ENST00000349718_chr3_32483330_+_90aa VTLLIAFICVRSSLWTNYSAYSYFEVVTICDLIMILAFYLVHLFRFYRVLTCISWPLSIFGFMATFLCMASIWLSYKISCVTQSTDAAVX >In-frame_GLB1_ENST00000307377_chr3_33055546_-_CMTM7_ENST00000334983_chr3_32483330_+_123aa VTLLIAFICVRSSLWTNYSAYSYFEVVTICDLIMILAFYLVHLFRFYRVLTCISWPLSELLHYLIGTLLLLIASIVAASKSYNQSGLVAG >In-frame_GLB1_ENST00000307377_chr3_33055546_-_CMTM7_ENST00000349718_chr3_32483330_+_90aa VTLLIAFICVRSSLWTNYSAYSYFEVVTICDLIMILAFYLVHLFRFYRVLTCISWPLSIFGFMATFLCMASIWLSYKISCVTQSTDAAVX |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_GLB1_ENST00000307363_chr3_33055546_-_CMTM7_ENST00000334983_chr3_32483330_+_369nt GTCACCCTGCTGATTGCCTTCATCTGTGTGCGGAGCTCCCTGTGGACCAACTACAGCGCCTACAGCTACTTTGAAGTGGTCACCATTTGC GACTTGATAATGATCCTCGCCTTTTACCTGGTCCACCTCTTCCGCTTCTACCGCGTGCTCACCTGTATCAGCTGGCCCCTGTCGGAACTT CTGCACTATTTAATCGGTACCCTGCTCCTCCTCATCGCCTCCATTGTGGCAGCTTCCAAGAGTTACAACCAGAGCGGACTGGTAGCCGGA GCGATCTTTGGTTTCATGGCCACCTTCCTCTGCATGGCAAGCATATGGCTGTCCTATAAGATCTCGTGTGTAACCCAGTCCACAGATGCA >In-frame_GLB1_ENST00000307363_chr3_33055546_-_CMTM7_ENST00000349718_chr3_32483330_+_270nt GTCACCCTGCTGATTGCCTTCATCTGTGTGCGGAGCTCCCTGTGGACCAACTACAGCGCCTACAGCTACTTTGAAGTGGTCACCATTTGC GACTTGATAATGATCCTCGCCTTTTACCTGGTCCACCTCTTCCGCTTCTACCGCGTGCTCACCTGTATCAGCTGGCCCCTGTCGATCTTT GGTTTCATGGCCACCTTCCTCTGCATGGCAAGCATATGGCTGTCCTATAAGATCTCGTGTGTAACCCAGTCCACAGATGCAGCCGTCTGA >In-frame_GLB1_ENST00000445488_chr3_33055546_-_CMTM7_ENST00000334983_chr3_32483330_+_369nt GTCACCCTGCTGATTGCCTTCATCTGTGTGCGGAGCTCCCTGTGGACCAACTACAGCGCCTACAGCTACTTTGAAGTGGTCACCATTTGC GACTTGATAATGATCCTCGCCTTTTACCTGGTCCACCTCTTCCGCTTCTACCGCGTGCTCACCTGTATCAGCTGGCCCCTGTCGGAACTT CTGCACTATTTAATCGGTACCCTGCTCCTCCTCATCGCCTCCATTGTGGCAGCTTCCAAGAGTTACAACCAGAGCGGACTGGTAGCCGGA GCGATCTTTGGTTTCATGGCCACCTTCCTCTGCATGGCAAGCATATGGCTGTCCTATAAGATCTCGTGTGTAACCCAGTCCACAGATGCA >In-frame_GLB1_ENST00000445488_chr3_33055546_-_CMTM7_ENST00000349718_chr3_32483330_+_270nt GTCACCCTGCTGATTGCCTTCATCTGTGTGCGGAGCTCCCTGTGGACCAACTACAGCGCCTACAGCTACTTTGAAGTGGTCACCATTTGC GACTTGATAATGATCCTCGCCTTTTACCTGGTCCACCTCTTCCGCTTCTACCGCGTGCTCACCTGTATCAGCTGGCCCCTGTCGATCTTT GGTTTCATGGCCACCTTCCTCTGCATGGCAAGCATATGGCTGTCCTATAAGATCTCGTGTGTAACCCAGTCCACAGATGCAGCCGTCTGA >In-frame_GLB1_ENST00000307377_chr3_33055546_-_CMTM7_ENST00000334983_chr3_32483330_+_369nt GTCACCCTGCTGATTGCCTTCATCTGTGTGCGGAGCTCCCTGTGGACCAACTACAGCGCCTACAGCTACTTTGAAGTGGTCACCATTTGC GACTTGATAATGATCCTCGCCTTTTACCTGGTCCACCTCTTCCGCTTCTACCGCGTGCTCACCTGTATCAGCTGGCCCCTGTCGGAACTT CTGCACTATTTAATCGGTACCCTGCTCCTCCTCATCGCCTCCATTGTGGCAGCTTCCAAGAGTTACAACCAGAGCGGACTGGTAGCCGGA GCGATCTTTGGTTTCATGGCCACCTTCCTCTGCATGGCAAGCATATGGCTGTCCTATAAGATCTCGTGTGTAACCCAGTCCACAGATGCA >In-frame_GLB1_ENST00000307377_chr3_33055546_-_CMTM7_ENST00000349718_chr3_32483330_+_270nt GTCACCCTGCTGATTGCCTTCATCTGTGTGCGGAGCTCCCTGTGGACCAACTACAGCGCCTACAGCTACTTTGAAGTGGTCACCATTTGC GACTTGATAATGATCCTCGCCTTTTACCTGGTCCACCTCTTCCGCTTCTACCGCGTGCTCACCTGTATCAGCTGGCCCCTGTCGATCTTT GGTTTCATGGCCACCTTCCTCTGCATGGCAAGCATATGGCTGTCCTATAAGATCTCGTGTGTAACCCAGTCCACAGATGCAGCCGTCTGA |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_GLB1_ENST00000307363_chr3_33055546_-_CMTM7_ENST00000334983_chr3_32483330_+_3522nt CACAGCGGGGCGGGGCGCGGGGCTGAGCAGGCGCGAGGGCTGGCTGCTGGGCCGACGAGGGGCGGTGCCAGGCCGTGGGTCCTTAGTCAA GTGACGCGAAGCGGCCGGCCTGGGCGCCGACTGCAGAGCCGGGAGGCTGGTGGTCATGCCGGGGTTCCTGGTTCGCATCCTCCCTCTGTT GCTGGTTCTGCTGCTTCTGGGCCCTACGCGCGGCTTGCGCAATGCCACCCAGAGGATGTTTGAAATTGACTATAGCCGGGACTCCTTCCT CAAGGATGGCCAGCCATTTCGCTACATCTCAGGAAGCATTCACTACTCCCGTGTGCCCCGCTTCTACTGGAAGGACCGGCTGCTGAAGAT GAAGATGGCTGGGCTGAACGCCATCCAGACGTATGTGCCCTGGAACTTTCATGAGCCCTGGCCAGGACAGTACCAGTTTTCTGAGGACCA TGATGTGGAATATTTTCTTCGGCTGGCTCATGAGCTGGGACTGCTGGTTATCCTGAGGCCCGGGCCCTACATCTGTGCAGAGTGGGAAAT GGGAGGATTACCTGCTTGGCTGCTAGAGAAAGAGTCTATTCTTCTCCGCTCCTCCGACCCAGATTACCTGGCAGCTGTGGACAAGTGGTT GGGAGTCCTTCTGCCCAAGATGAAGCCTCTCCTCTATCAGAATGGAGGGCCAGTTATAACAGTGCAGGTTGAAAATGAATATGGCAGCTA CTTTGCCTGTGATTTTGACTACCTGCGCTTCCTGCAGAAGCGCTTTCGCCACCATCTGGGGGATGATGTGGTTCTGTTTACCACTGATGG AGCACATAAAACATTCCTGAAATGTGGGGCCCTGCAGGGCCTCTACACCACGGTGGACTTTGGAACAGGCAGCAACATCACAGATGCTTT CCTAAGCCAGAGGAAGTGTGAGCCCAAAGGACCCTTGATCAATTCTGAATTCTATACTGGCTGGCTAGATCACTGGGGCCAACCTCACTC CACAATCAAGACCGAAGCAGTGGCTTCCTCCCTCTATGATATACTTGCCCGTGGGGCGAGTGTGAACTTGTACATGTTTATAGGTGGGAC CAATTTTGCCTATTGGAATGGGGCCAACTCACCCTATGCAGCACAGCCCACCAGCTACGACTATGATGCCCCACTGAGTGAGGCTGGGGA CCTCACTGAGAAGTATTTTGCTCTGCGAAACATCATCCAGAAGTTTGAAAAAGTACCAGAAGGTCCTATCCCTCCATCTACACCAAAGTT TGCATATGGAAAGGTCACTTTGGAAAAGTTAAAGACAGTGGGAGCAGCTCTGGACATTCTGTGTCCCTCTGGGCCCATCAAAAGCCTTTA TCCCTTGACATTTATCCAGGTGAAACAGCATTATGGGTTTGTGCTGTACCGGACAACACTTCCTCAAGATTGCAGCAACCCAGCACCTCT CTCTTCACCCCTCAATGGAGTCCACGATCGAGCATATGTTGCTGTGGATGGGATCCCCCAGGGAGTCCTTGAGCGAAACAATGTGATCAC TCTGAACATAACAGGGAAAGCTGGAGCCACTCTGGACCTTCTGGTAGAGAACATGGGACGTGTGAACTATGGTGCATATATCAACGATTT TAAGGGTTTGGTTTCTAACCTGACTCTCAGTTCCAATATCCTCACGGACTGGACGATCTTTCCACTGGACACTGAGGATGCAGTGTGCAG CCACCTGGGGGGCTGGGGACACCGTGACAGTGGCCACCATGATGAAGCCTGGGCCCACAACTCATCCAACTACACGCTCCCGGCCTTTTA TATGGGGAACTTCTCCATTCCCAGTGGGATCCCAGACTTGCCCCAGGACACCTTTATCCAGTTTCCTGGATGGACCAAGGTCACCCTGCT GATTGCCTTCATCTGTGTGCGGAGCTCCCTGTGGACCAACTACAGCGCCTACAGCTACTTTGAAGTGGTCACCATTTGCGACTTGATAAT GATCCTCGCCTTTTACCTGGTCCACCTCTTCCGCTTCTACCGCGTGCTCACCTGTATCAGCTGGCCCCTGTCGGAACTTCTGCACTATTT AATCGGTACCCTGCTCCTCCTCATCGCCTCCATTGTGGCAGCTTCCAAGAGTTACAACCAGAGCGGACTGGTAGCCGGAGCGATCTTTGG TTTCATGGCCACCTTCCTCTGCATGGCAAGCATATGGCTGTCCTATAAGATCTCGTGTGTAACCCAGTCCACAGATGCAGCCGTCTGATG AGGCCACAACCCCTAGGCCCCTCAGGAGCTTTGCAGAGAGGAGGACGTGTACTCCAGGCGAGGCCTCTGGACCTGTGTTCCTGTGCCAAA GTCCTGTCAGGCTGGTGGGCACCAGGAAAGGCCTGCACCCTCTTCCTGCTCTCCCAGGAAGCCAGCTCCCTGAGCTCCTGAGCCAGCCGG AAACTCTTCCTCCAGCCTTCCGGGGAGAACATCCCTCCCATTCTGGGAAAGGAAAGCAGCCTCCAGGGAAATGTTTTCTGCCTTCCTGCT TCTAGAACCACCTCAGGTACTGATGAACCCCACTTAGCACAGCTGAAGGGGTTTGTGAATACTCCCGCCTAAATCCCTTCTACTTCACTC CTCAGGGGAGTGAAGTGCCTTAAGAAACAAAGCCCTGTCCTAATTTATCTAGCTTGTCAGTCCGGTCTTAGAGATACCCTCTTTCCTGAA GTGAGGCGTGCCTGTAGAAACACTATGTGGTCAGCCTGTCCCCAAGGAGATCTTGTGTCTCCTCTCCATCTCTGCCTTTGTTACCAGTGT GCATGTGTTTGTGTGTTTTTTAATAAAATATTGACTCGGCCAGTTGCACAAGGATTTCTTATTGAACCAGATGAAGGCTGTAAAACCTGG CCTGAAACAGTTTCCATTCGAGCTTGTGTCTGGCCCATGGCCCTCCACCCGTGCTCTGTGTGTGCCCCTTGCTGAACTGCTGGACTTCAG GTTTTCTCTCCATCTTGGGGGATAGTATAGCAGGGCAGAGTTTTAGGTAAACATGTGCAGGTTCTCAATTATATTCACGTCCTCCTTCTC CTGCAATACCAATCTTCTCATTTTGGAAAGAGCTTTAGAGCAAGCTAAGGGTTGTGTTTACACTATGATGATTAATGATCTCGGCCTAAA TGTGCTGTTTCGCTGATCTTGAGCTGCTCAGTTGGCTAGAAAAAGGAGGGATGGAACAATGTTTGAGCAACCCCGTGTGCAAGGACCTAC ATTCACAACCACATCTAATAGCGATGGTAGTGACTGCAAGGGGGCAGGTTATAGGACCACATTTTTAGAAATGAAATCGGGGCTCCATCC CCAGGCACAGGGCAAGCCAGTGAGGAGCTGGGCTCAGGATCTAGGTCTGCCTGACTCCCAGCCCCATCCTTGCCTCTGCTGAGTGTTGCC GGAAATGGAAGCAGCCCCTGTGGGCTTTGAGCTGGAGCTCTGGGGCTACTCTTGTGGCTGCTGGCCAGCTCGGGGCATCGGGTTCTGTCT >In-frame_GLB1_ENST00000307363_chr3_33055546_-_CMTM7_ENST00000349718_chr3_32483330_+_2725nt CACAGCGGGGCGGGGCGCGGGGCTGAGCAGGCGCGAGGGCTGGCTGCTGGGCCGACGAGGGGCGGTGCCAGGCCGTGGGTCCTTAGTCAA GTGACGCGAAGCGGCCGGCCTGGGCGCCGACTGCAGAGCCGGGAGGCTGGTGGTCATGCCGGGGTTCCTGGTTCGCATCCTCCCTCTGTT GCTGGTTCTGCTGCTTCTGGGCCCTACGCGCGGCTTGCGCAATGCCACCCAGAGGATGTTTGAAATTGACTATAGCCGGGACTCCTTCCT CAAGGATGGCCAGCCATTTCGCTACATCTCAGGAAGCATTCACTACTCCCGTGTGCCCCGCTTCTACTGGAAGGACCGGCTGCTGAAGAT GAAGATGGCTGGGCTGAACGCCATCCAGACGTATGTGCCCTGGAACTTTCATGAGCCCTGGCCAGGACAGTACCAGTTTTCTGAGGACCA TGATGTGGAATATTTTCTTCGGCTGGCTCATGAGCTGGGACTGCTGGTTATCCTGAGGCCCGGGCCCTACATCTGTGCAGAGTGGGAAAT GGGAGGATTACCTGCTTGGCTGCTAGAGAAAGAGTCTATTCTTCTCCGCTCCTCCGACCCAGATTACCTGGCAGCTGTGGACAAGTGGTT GGGAGTCCTTCTGCCCAAGATGAAGCCTCTCCTCTATCAGAATGGAGGGCCAGTTATAACAGTGCAGGTTGAAAATGAATATGGCAGCTA CTTTGCCTGTGATTTTGACTACCTGCGCTTCCTGCAGAAGCGCTTTCGCCACCATCTGGGGGATGATGTGGTTCTGTTTACCACTGATGG AGCACATAAAACATTCCTGAAATGTGGGGCCCTGCAGGGCCTCTACACCACGGTGGACTTTGGAACAGGCAGCAACATCACAGATGCTTT CCTAAGCCAGAGGAAGTGTGAGCCCAAAGGACCCTTGATCAATTCTGAATTCTATACTGGCTGGCTAGATCACTGGGGCCAACCTCACTC CACAATCAAGACCGAAGCAGTGGCTTCCTCCCTCTATGATATACTTGCCCGTGGGGCGAGTGTGAACTTGTACATGTTTATAGGTGGGAC CAATTTTGCCTATTGGAATGGGGCCAACTCACCCTATGCAGCACAGCCCACCAGCTACGACTATGATGCCCCACTGAGTGAGGCTGGGGA CCTCACTGAGAAGTATTTTGCTCTGCGAAACATCATCCAGAAGTTTGAAAAAGTACCAGAAGGTCCTATCCCTCCATCTACACCAAAGTT TGCATATGGAAAGGTCACTTTGGAAAAGTTAAAGACAGTGGGAGCAGCTCTGGACATTCTGTGTCCCTCTGGGCCCATCAAAAGCCTTTA TCCCTTGACATTTATCCAGGTGAAACAGCATTATGGGTTTGTGCTGTACCGGACAACACTTCCTCAAGATTGCAGCAACCCAGCACCTCT CTCTTCACCCCTCAATGGAGTCCACGATCGAGCATATGTTGCTGTGGATGGGATCCCCCAGGGAGTCCTTGAGCGAAACAATGTGATCAC TCTGAACATAACAGGGAAAGCTGGAGCCACTCTGGACCTTCTGGTAGAGAACATGGGACGTGTGAACTATGGTGCATATATCAACGATTT TAAGGGTTTGGTTTCTAACCTGACTCTCAGTTCCAATATCCTCACGGACTGGACGATCTTTCCACTGGACACTGAGGATGCAGTGTGCAG CCACCTGGGGGGCTGGGGACACCGTGACAGTGGCCACCATGATGAAGCCTGGGCCCACAACTCATCCAACTACACGCTCCCGGCCTTTTA TATGGGGAACTTCTCCATTCCCAGTGGGATCCCAGACTTGCCCCAGGACACCTTTATCCAGTTTCCTGGATGGACCAAGGTCACCCTGCT GATTGCCTTCATCTGTGTGCGGAGCTCCCTGTGGACCAACTACAGCGCCTACAGCTACTTTGAAGTGGTCACCATTTGCGACTTGATAAT GATCCTCGCCTTTTACCTGGTCCACCTCTTCCGCTTCTACCGCGTGCTCACCTGTATCAGCTGGCCCCTGTCGATCTTTGGTTTCATGGC CACCTTCCTCTGCATGGCAAGCATATGGCTGTCCTATAAGATCTCGTGTGTAACCCAGTCCACAGATGCAGCCGTCTGATGAGGCCACAA CCCCTAGGCCCCTCAGGAGCTTTGCAGAGAGGAGGACGTGTACTCCAGGCGAGGCCTCTGGACCTGTGTTCCTGTGCCAAAGTCCTGTCA GGCTGGTGGGCACCAGGAAAGGCCTGCACCCTCTTCCTGCTCTCCCAGGAAGCCAGCTCCCTGAGCTCCTGAGCCAGCCGGAAACTCTTC CTCCAGCCTTCCGGGGAGAACATCCCTCCCATTCTGGGAAAGGAAAGCAGCCTCCAGGGAAATGTTTTCTGCCTTCCTGCTTCTAGAACC ACCTCAGGTACTGATGAACCCCACTTAGCACAGCTGAAGGGGTTTGTGAATACTCCCGCCTAAATCCCTTCTACTTCACTCCTCAGGGGA GTGAAGTGCCTTAAGAAACAAAGCCCTGTCCTAATTTATCTAGCTTGTCAGTCCGGTCTTAGAGATACCCTCTTTCCTGAAGTGAGGCGT GCCTGTAGAAACACTATGTGGTCAGCCTGTCCCCAAGGAGATCTTGTGTCTCCTCTCCATCTCTGCCTTTGTTACCAGTGTGCATGTGTT >In-frame_GLB1_ENST00000445488_chr3_33055546_-_CMTM7_ENST00000334983_chr3_32483330_+_3582nt AGTCAAGTGACGCGAAGCGGCCGGCCTGGGCGCCGACTGCAGAGCCGGGAGGCTGGTGGTCATGCCGGGGTTCCTGGTTCGCATCCTCCC TCTGTTGCTGGTTCTGCTGCTTCTGGGCCCTACGCGCGGCTTGCGCTCTCGATTCCTTCCTTGGGCTTTTCATCTGCCACGGCAAGCGCC TAAGTCTCAGCTGCCGCTTCACAAAAGAGGTACCAAGACTGCACCGAATGAGCACGCAAGCAGCAACAGGAGTGGGAGAAGAAGGAGGCG GCAGCAGTGGAATGCCACCCAGAGGATGTTTGAAATTGACTATAGCCGGGACTCCTTCCTCAAGGATGGCCAGCCATTTCGCTACATCTC AGGAAGCATTCACTACTCCCGTGTGCCCCGCTTCTACTGGAAGGACCGGCTGCTGAAGATGAAGATGGCTGGGCTGAACGCCATCCAGAC GTATGTGCCCTGGAACTTTCATGAGCCCTGGCCAGGACAGTACCAGTTTTCTGAGGACCATGATGTGGAATATTTTCTTCGGCTGGCTCA TGAGCTGGGACTGCTGGTTATCCTGAGGCCCGGGCCCTACATCTGTGCAGAGTGGGAAATGGGAGGATTACCTGCTTGGCTGCTAGAGAA AGAGTCTATTCTTCTCCGCTCCTCCGACCCAGATTACCTGGCAGCTGTGGACAAGTGGTTGGGAGTCCTTCTGCCCAAGATGAAGCCTCT CCTCTATCAGAATGGAGGGCCAGTTATAACAGTGCAGGTTGAAAATGAATATGGCAGCTACTTTGCCTGTGATTTTGACTACCTGCGCTT CCTGCAGAAGCGCTTTCGCCACCATCTGGGGGATGATGTGGTTCTGTTTACCACTGATGGAGCACATAAAACATTCCTGAAATGTGGGGC CCTGCAGGGCCTCTACACCACGGTGGACTTTGGAACAGGCAGCAACATCACAGATGCTTTCCTAAGCCAGAGGAAGTGTGAGCCCAAAGG ACCCTTGATCAATTCTGAATTCTATACTGGCTGGCTAGATCACTGGGGCCAACCTCACTCCACAATCAAGACCGAAGCAGTGGCTTCCTC CCTCTATGATATACTTGCCCGTGGGGCGAGTGTGAACTTGTACATGTTTATAGGTGGGACCAATTTTGCCTATTGGAATGGGGCCAACTC ACCCTATGCAGCACAGCCCACCAGCTACGACTATGATGCCCCACTGAGTGAGGCTGGGGACCTCACTGAGAAGTATTTTGCTCTGCGAAA CATCATCCAGAAGTTTGAAAAAGTACCAGAAGGTCCTATCCCTCCATCTACACCAAAGTTTGCATATGGAAAGGTCACTTTGGAAAAGTT AAAGACAGTGGGAGCAGCTCTGGACATTCTGTGTCCCTCTGGGCCCATCAAAAGCCTTTATCCCTTGACATTTATCCAGGTGAAACAGCA TTATGGGTTTGTGCTGTACCGGACAACACTTCCTCAAGATTGCAGCAACCCAGCACCTCTCTCTTCACCCCTCAATGGAGTCCACGATCG AGCATATGTTGCTGTGGATGGGATCCCCCAGGGAGTCCTTGAGCGAAACAATGTGATCACTCTGAACATAACAGGGAAAGCTGGAGCCAC TCTGGACCTTCTGGTAGAGAACATGGGACGTGTGAACTATGGTGCATATATCAACGATTTTAAGGGTTTGGTTTCTAACCTGACTCTCAG TTCCAATATCCTCACGGACTGGACGATCTTTCCACTGGACACTGAGGATGCAGTGTGCAGCCACCTGGGGGGCTGGGGACACCGTGACAG TGGCCACCATGATGAAGCCTGGGCCCACAACTCATCCAACTACACGCTCCCGGCCTTTTATATGGGGAACTTCTCCATTCCCAGTGGGAT CCCAGACTTGCCCCAGGACACCTTTATCCAGTTTCCTGGATGGACCAAGGTCACCCTGCTGATTGCCTTCATCTGTGTGCGGAGCTCCCT GTGGACCAACTACAGCGCCTACAGCTACTTTGAAGTGGTCACCATTTGCGACTTGATAATGATCCTCGCCTTTTACCTGGTCCACCTCTT CCGCTTCTACCGCGTGCTCACCTGTATCAGCTGGCCCCTGTCGGAACTTCTGCACTATTTAATCGGTACCCTGCTCCTCCTCATCGCCTC CATTGTGGCAGCTTCCAAGAGTTACAACCAGAGCGGACTGGTAGCCGGAGCGATCTTTGGTTTCATGGCCACCTTCCTCTGCATGGCAAG CATATGGCTGTCCTATAAGATCTCGTGTGTAACCCAGTCCACAGATGCAGCCGTCTGATGAGGCCACAACCCCTAGGCCCCTCAGGAGCT TTGCAGAGAGGAGGACGTGTACTCCAGGCGAGGCCTCTGGACCTGTGTTCCTGTGCCAAAGTCCTGTCAGGCTGGTGGGCACCAGGAAAG GCCTGCACCCTCTTCCTGCTCTCCCAGGAAGCCAGCTCCCTGAGCTCCTGAGCCAGCCGGAAACTCTTCCTCCAGCCTTCCGGGGAGAAC ATCCCTCCCATTCTGGGAAAGGAAAGCAGCCTCCAGGGAAATGTTTTCTGCCTTCCTGCTTCTAGAACCACCTCAGGTACTGATGAACCC CACTTAGCACAGCTGAAGGGGTTTGTGAATACTCCCGCCTAAATCCCTTCTACTTCACTCCTCAGGGGAGTGAAGTGCCTTAAGAAACAA AGCCCTGTCCTAATTTATCTAGCTTGTCAGTCCGGTCTTAGAGATACCCTCTTTCCTGAAGTGAGGCGTGCCTGTAGAAACACTATGTGG TCAGCCTGTCCCCAAGGAGATCTTGTGTCTCCTCTCCATCTCTGCCTTTGTTACCAGTGTGCATGTGTTTGTGTGTTTTTTAATAAAATA TTGACTCGGCCAGTTGCACAAGGATTTCTTATTGAACCAGATGAAGGCTGTAAAACCTGGCCTGAAACAGTTTCCATTCGAGCTTGTGTC TGGCCCATGGCCCTCCACCCGTGCTCTGTGTGTGCCCCTTGCTGAACTGCTGGACTTCAGGTTTTCTCTCCATCTTGGGGGATAGTATAG CAGGGCAGAGTTTTAGGTAAACATGTGCAGGTTCTCAATTATATTCACGTCCTCCTTCTCCTGCAATACCAATCTTCTCATTTTGGAAAG AGCTTTAGAGCAAGCTAAGGGTTGTGTTTACACTATGATGATTAATGATCTCGGCCTAAATGTGCTGTTTCGCTGATCTTGAGCTGCTCA GTTGGCTAGAAAAAGGAGGGATGGAACAATGTTTGAGCAACCCCGTGTGCAAGGACCTACATTCACAACCACATCTAATAGCGATGGTAG TGACTGCAAGGGGGCAGGTTATAGGACCACATTTTTAGAAATGAAATCGGGGCTCCATCCCCAGGCACAGGGCAAGCCAGTGAGGAGCTG GGCTCAGGATCTAGGTCTGCCTGACTCCCAGCCCCATCCTTGCCTCTGCTGAGTGTTGCCGGAAATGGAAGCAGCCCCTGTGGGCTTTGA >In-frame_GLB1_ENST00000445488_chr3_33055546_-_CMTM7_ENST00000349718_chr3_32483330_+_2785nt AGTCAAGTGACGCGAAGCGGCCGGCCTGGGCGCCGACTGCAGAGCCGGGAGGCTGGTGGTCATGCCGGGGTTCCTGGTTCGCATCCTCCC TCTGTTGCTGGTTCTGCTGCTTCTGGGCCCTACGCGCGGCTTGCGCTCTCGATTCCTTCCTTGGGCTTTTCATCTGCCACGGCAAGCGCC TAAGTCTCAGCTGCCGCTTCACAAAAGAGGTACCAAGACTGCACCGAATGAGCACGCAAGCAGCAACAGGAGTGGGAGAAGAAGGAGGCG GCAGCAGTGGAATGCCACCCAGAGGATGTTTGAAATTGACTATAGCCGGGACTCCTTCCTCAAGGATGGCCAGCCATTTCGCTACATCTC AGGAAGCATTCACTACTCCCGTGTGCCCCGCTTCTACTGGAAGGACCGGCTGCTGAAGATGAAGATGGCTGGGCTGAACGCCATCCAGAC GTATGTGCCCTGGAACTTTCATGAGCCCTGGCCAGGACAGTACCAGTTTTCTGAGGACCATGATGTGGAATATTTTCTTCGGCTGGCTCA TGAGCTGGGACTGCTGGTTATCCTGAGGCCCGGGCCCTACATCTGTGCAGAGTGGGAAATGGGAGGATTACCTGCTTGGCTGCTAGAGAA AGAGTCTATTCTTCTCCGCTCCTCCGACCCAGATTACCTGGCAGCTGTGGACAAGTGGTTGGGAGTCCTTCTGCCCAAGATGAAGCCTCT CCTCTATCAGAATGGAGGGCCAGTTATAACAGTGCAGGTTGAAAATGAATATGGCAGCTACTTTGCCTGTGATTTTGACTACCTGCGCTT CCTGCAGAAGCGCTTTCGCCACCATCTGGGGGATGATGTGGTTCTGTTTACCACTGATGGAGCACATAAAACATTCCTGAAATGTGGGGC CCTGCAGGGCCTCTACACCACGGTGGACTTTGGAACAGGCAGCAACATCACAGATGCTTTCCTAAGCCAGAGGAAGTGTGAGCCCAAAGG ACCCTTGATCAATTCTGAATTCTATACTGGCTGGCTAGATCACTGGGGCCAACCTCACTCCACAATCAAGACCGAAGCAGTGGCTTCCTC CCTCTATGATATACTTGCCCGTGGGGCGAGTGTGAACTTGTACATGTTTATAGGTGGGACCAATTTTGCCTATTGGAATGGGGCCAACTC ACCCTATGCAGCACAGCCCACCAGCTACGACTATGATGCCCCACTGAGTGAGGCTGGGGACCTCACTGAGAAGTATTTTGCTCTGCGAAA CATCATCCAGAAGTTTGAAAAAGTACCAGAAGGTCCTATCCCTCCATCTACACCAAAGTTTGCATATGGAAAGGTCACTTTGGAAAAGTT AAAGACAGTGGGAGCAGCTCTGGACATTCTGTGTCCCTCTGGGCCCATCAAAAGCCTTTATCCCTTGACATTTATCCAGGTGAAACAGCA TTATGGGTTTGTGCTGTACCGGACAACACTTCCTCAAGATTGCAGCAACCCAGCACCTCTCTCTTCACCCCTCAATGGAGTCCACGATCG AGCATATGTTGCTGTGGATGGGATCCCCCAGGGAGTCCTTGAGCGAAACAATGTGATCACTCTGAACATAACAGGGAAAGCTGGAGCCAC TCTGGACCTTCTGGTAGAGAACATGGGACGTGTGAACTATGGTGCATATATCAACGATTTTAAGGGTTTGGTTTCTAACCTGACTCTCAG TTCCAATATCCTCACGGACTGGACGATCTTTCCACTGGACACTGAGGATGCAGTGTGCAGCCACCTGGGGGGCTGGGGACACCGTGACAG TGGCCACCATGATGAAGCCTGGGCCCACAACTCATCCAACTACACGCTCCCGGCCTTTTATATGGGGAACTTCTCCATTCCCAGTGGGAT CCCAGACTTGCCCCAGGACACCTTTATCCAGTTTCCTGGATGGACCAAGGTCACCCTGCTGATTGCCTTCATCTGTGTGCGGAGCTCCCT GTGGACCAACTACAGCGCCTACAGCTACTTTGAAGTGGTCACCATTTGCGACTTGATAATGATCCTCGCCTTTTACCTGGTCCACCTCTT CCGCTTCTACCGCGTGCTCACCTGTATCAGCTGGCCCCTGTCGATCTTTGGTTTCATGGCCACCTTCCTCTGCATGGCAAGCATATGGCT GTCCTATAAGATCTCGTGTGTAACCCAGTCCACAGATGCAGCCGTCTGATGAGGCCACAACCCCTAGGCCCCTCAGGAGCTTTGCAGAGA GGAGGACGTGTACTCCAGGCGAGGCCTCTGGACCTGTGTTCCTGTGCCAAAGTCCTGTCAGGCTGGTGGGCACCAGGAAAGGCCTGCACC CTCTTCCTGCTCTCCCAGGAAGCCAGCTCCCTGAGCTCCTGAGCCAGCCGGAAACTCTTCCTCCAGCCTTCCGGGGAGAACATCCCTCCC ATTCTGGGAAAGGAAAGCAGCCTCCAGGGAAATGTTTTCTGCCTTCCTGCTTCTAGAACCACCTCAGGTACTGATGAACCCCACTTAGCA CAGCTGAAGGGGTTTGTGAATACTCCCGCCTAAATCCCTTCTACTTCACTCCTCAGGGGAGTGAAGTGCCTTAAGAAACAAAGCCCTGTC CTAATTTATCTAGCTTGTCAGTCCGGTCTTAGAGATACCCTCTTTCCTGAAGTGAGGCGTGCCTGTAGAAACACTATGTGGTCAGCCTGT >In-frame_GLB1_ENST00000307377_chr3_33055546_-_CMTM7_ENST00000334983_chr3_32483330_+_3045nt AGTCAAGTGACGCGAAGCGGCCGGCCTGGGCGCCGACTGCAGAGCCGGGAGGCTGGTGGTCATGCCGGGGTTCCTGGTTCGCATCCTCCC TCTGTTGCTGGTTCTGCTGCTTCTGGGCCCTACGCGCGGCTTGCGCAATGCCACCCAGAGGATGTTTGAAATTGACTATAGCCGGGACTC CTTCCTCAAGGATGGCCAGCCATTTCGCTACATCTCAGGAAGCATTCACTACTCCCGTGTGCCCCGCTTCTACTGGAAGGACCGGCTGCT GAAGATGAAGATGGCTGGGCTGAACGCCATCCAGACATTACCTGGCAGCTGTGGACAAGTGGTTGGGAGTCCTTCTGCCCAAGATGAAGC CTCTCCTCTATCAGAATGGAGGGCCAGTTATAACAGTGCAGGCAGCAACATCACAGATGCTTTCCTAAGCCAGAGGAAGTGTGAGCCCAA AGGACCCTTGATCAATTCTGAATTCTATACTGGCTGGCTAGATCACTGGGGCCAACCTCACTCCACAATCAAGACCGAAGCAGTGGCTTC CTCCCTCTATGATATACTTGCCCGTGGGGCGAGTGTGAACTTGTACATGTTTATAGGTGGGACCAATTTTGCCTATTGGAATGGGGCCAA CTCACCCTATGCAGCACAGCCCACCAGCTACGACTATGATGCCCCACTGAGTGAGGCTGGGGACCTCACTGAGAAGTATTTTGCTCTGCG AAACATCATCCAGAAGTTTGAAAAAGTACCAGAAGGTCCTATCCCTCCATCTACACCAAAGTTTGCATATGGAAAGGTCACTTTGGAAAA GTTAAAGACAGTGGGAGCAGCTCTGGACATTCTGTGTCCCTCTGGGCCCATCAAAAGCCTTTATCCCTTGACATTTATCCAGGTGAAACA GCATTATGGGTTTGTGCTGTACCGGACAACACTTCCTCAAGATTGCAGCAACCCAGCACCTCTCTCTTCACCCCTCAATGGAGTCCACGA TCGAGCATATGTTGCTGTGGATGGGATCCCCCAGGGAGTCCTTGAGCGAAACAATGTGATCACTCTGAACATAACAGGGAAAGCTGGAGC CACTCTGGACCTTCTGGTAGAGAACATGGGACGTGTGAACTATGGTGCATATATCAACGATTTTAAGGGTTTGGTTTCTAACCTGACTCT CAGTTCCAATATCCTCACGGACTGGACGATCTTTCCACTGGACACTGAGGATGCAGTGTGCAGCCACCTGGGGGGCTGGGGACACCGTGA CAGTGGCCACCATGATGAAGCCTGGGCCCACAACTCATCCAACTACACGCTCCCGGCCTTTTATATGGGGAACTTCTCCATTCCCAGTGG GATCCCAGACTTGCCCCAGGACACCTTTATCCAGTTTCCTGGATGGACCAAGGTCACCCTGCTGATTGCCTTCATCTGTGTGCGGAGCTC CCTGTGGACCAACTACAGCGCCTACAGCTACTTTGAAGTGGTCACCATTTGCGACTTGATAATGATCCTCGCCTTTTACCTGGTCCACCT CTTCCGCTTCTACCGCGTGCTCACCTGTATCAGCTGGCCCCTGTCGGAACTTCTGCACTATTTAATCGGTACCCTGCTCCTCCTCATCGC CTCCATTGTGGCAGCTTCCAAGAGTTACAACCAGAGCGGACTGGTAGCCGGAGCGATCTTTGGTTTCATGGCCACCTTCCTCTGCATGGC AAGCATATGGCTGTCCTATAAGATCTCGTGTGTAACCCAGTCCACAGATGCAGCCGTCTGATGAGGCCACAACCCCTAGGCCCCTCAGGA GCTTTGCAGAGAGGAGGACGTGTACTCCAGGCGAGGCCTCTGGACCTGTGTTCCTGTGCCAAAGTCCTGTCAGGCTGGTGGGCACCAGGA AAGGCCTGCACCCTCTTCCTGCTCTCCCAGGAAGCCAGCTCCCTGAGCTCCTGAGCCAGCCGGAAACTCTTCCTCCAGCCTTCCGGGGAG AACATCCCTCCCATTCTGGGAAAGGAAAGCAGCCTCCAGGGAAATGTTTTCTGCCTTCCTGCTTCTAGAACCACCTCAGGTACTGATGAA CCCCACTTAGCACAGCTGAAGGGGTTTGTGAATACTCCCGCCTAAATCCCTTCTACTTCACTCCTCAGGGGAGTGAAGTGCCTTAAGAAA CAAAGCCCTGTCCTAATTTATCTAGCTTGTCAGTCCGGTCTTAGAGATACCCTCTTTCCTGAAGTGAGGCGTGCCTGTAGAAACACTATG TGGTCAGCCTGTCCCCAAGGAGATCTTGTGTCTCCTCTCCATCTCTGCCTTTGTTACCAGTGTGCATGTGTTTGTGTGTTTTTTAATAAA ATATTGACTCGGCCAGTTGCACAAGGATTTCTTATTGAACCAGATGAAGGCTGTAAAACCTGGCCTGAAACAGTTTCCATTCGAGCTTGT GTCTGGCCCATGGCCCTCCACCCGTGCTCTGTGTGTGCCCCTTGCTGAACTGCTGGACTTCAGGTTTTCTCTCCATCTTGGGGGATAGTA TAGCAGGGCAGAGTTTTAGGTAAACATGTGCAGGTTCTCAATTATATTCACGTCCTCCTTCTCCTGCAATACCAATCTTCTCATTTTGGA AAGAGCTTTAGAGCAAGCTAAGGGTTGTGTTTACACTATGATGATTAATGATCTCGGCCTAAATGTGCTGTTTCGCTGATCTTGAGCTGC TCAGTTGGCTAGAAAAAGGAGGGATGGAACAATGTTTGAGCAACCCCGTGTGCAAGGACCTACATTCACAACCACATCTAATAGCGATGG TAGTGACTGCAAGGGGGCAGGTTATAGGACCACATTTTTAGAAATGAAATCGGGGCTCCATCCCCAGGCACAGGGCAAGCCAGTGAGGAG CTGGGCTCAGGATCTAGGTCTGCCTGACTCCCAGCCCCATCCTTGCCTCTGCTGAGTGTTGCCGGAAATGGAAGCAGCCCCTGTGGGCTT >In-frame_GLB1_ENST00000307377_chr3_33055546_-_CMTM7_ENST00000349718_chr3_32483330_+_2248nt AGTCAAGTGACGCGAAGCGGCCGGCCTGGGCGCCGACTGCAGAGCCGGGAGGCTGGTGGTCATGCCGGGGTTCCTGGTTCGCATCCTCCC TCTGTTGCTGGTTCTGCTGCTTCTGGGCCCTACGCGCGGCTTGCGCAATGCCACCCAGAGGATGTTTGAAATTGACTATAGCCGGGACTC CTTCCTCAAGGATGGCCAGCCATTTCGCTACATCTCAGGAAGCATTCACTACTCCCGTGTGCCCCGCTTCTACTGGAAGGACCGGCTGCT GAAGATGAAGATGGCTGGGCTGAACGCCATCCAGACATTACCTGGCAGCTGTGGACAAGTGGTTGGGAGTCCTTCTGCCCAAGATGAAGC CTCTCCTCTATCAGAATGGAGGGCCAGTTATAACAGTGCAGGCAGCAACATCACAGATGCTTTCCTAAGCCAGAGGAAGTGTGAGCCCAA AGGACCCTTGATCAATTCTGAATTCTATACTGGCTGGCTAGATCACTGGGGCCAACCTCACTCCACAATCAAGACCGAAGCAGTGGCTTC CTCCCTCTATGATATACTTGCCCGTGGGGCGAGTGTGAACTTGTACATGTTTATAGGTGGGACCAATTTTGCCTATTGGAATGGGGCCAA CTCACCCTATGCAGCACAGCCCACCAGCTACGACTATGATGCCCCACTGAGTGAGGCTGGGGACCTCACTGAGAAGTATTTTGCTCTGCG AAACATCATCCAGAAGTTTGAAAAAGTACCAGAAGGTCCTATCCCTCCATCTACACCAAAGTTTGCATATGGAAAGGTCACTTTGGAAAA GTTAAAGACAGTGGGAGCAGCTCTGGACATTCTGTGTCCCTCTGGGCCCATCAAAAGCCTTTATCCCTTGACATTTATCCAGGTGAAACA GCATTATGGGTTTGTGCTGTACCGGACAACACTTCCTCAAGATTGCAGCAACCCAGCACCTCTCTCTTCACCCCTCAATGGAGTCCACGA TCGAGCATATGTTGCTGTGGATGGGATCCCCCAGGGAGTCCTTGAGCGAAACAATGTGATCACTCTGAACATAACAGGGAAAGCTGGAGC CACTCTGGACCTTCTGGTAGAGAACATGGGACGTGTGAACTATGGTGCATATATCAACGATTTTAAGGGTTTGGTTTCTAACCTGACTCT CAGTTCCAATATCCTCACGGACTGGACGATCTTTCCACTGGACACTGAGGATGCAGTGTGCAGCCACCTGGGGGGCTGGGGACACCGTGA CAGTGGCCACCATGATGAAGCCTGGGCCCACAACTCATCCAACTACACGCTCCCGGCCTTTTATATGGGGAACTTCTCCATTCCCAGTGG GATCCCAGACTTGCCCCAGGACACCTTTATCCAGTTTCCTGGATGGACCAAGGTCACCCTGCTGATTGCCTTCATCTGTGTGCGGAGCTC CCTGTGGACCAACTACAGCGCCTACAGCTACTTTGAAGTGGTCACCATTTGCGACTTGATAATGATCCTCGCCTTTTACCTGGTCCACCT CTTCCGCTTCTACCGCGTGCTCACCTGTATCAGCTGGCCCCTGTCGATCTTTGGTTTCATGGCCACCTTCCTCTGCATGGCAAGCATATG GCTGTCCTATAAGATCTCGTGTGTAACCCAGTCCACAGATGCAGCCGTCTGATGAGGCCACAACCCCTAGGCCCCTCAGGAGCTTTGCAG AGAGGAGGACGTGTACTCCAGGCGAGGCCTCTGGACCTGTGTTCCTGTGCCAAAGTCCTGTCAGGCTGGTGGGCACCAGGAAAGGCCTGC ACCCTCTTCCTGCTCTCCCAGGAAGCCAGCTCCCTGAGCTCCTGAGCCAGCCGGAAACTCTTCCTCCAGCCTTCCGGGGAGAACATCCCT CCCATTCTGGGAAAGGAAAGCAGCCTCCAGGGAAATGTTTTCTGCCTTCCTGCTTCTAGAACCACCTCAGGTACTGATGAACCCCACTTA GCACAGCTGAAGGGGTTTGTGAATACTCCCGCCTAAATCCCTTCTACTTCACTCCTCAGGGGAGTGAAGTGCCTTAAGAAACAAAGCCCT GTCCTAATTTATCTAGCTTGTCAGTCCGGTCTTAGAGATACCCTCTTTCCTGAAGTGAGGCGTGCCTGTAGAAACACTATGTGGTCAGCC |
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FusionGenePPI for GLB1_CMTM7 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| GLB1 | CTNNBIP1, NEU1, H2AFX, CSNK2B, TK1, PLK1, FBXO6, FOS, MEPCE, VCP, ABCE1, DNAJB2, DNAJB4, LGALS3, VAPA, ATP6AP2, C7orf43, TRAPPC10, TRAPPC9, TRAPPC6B, KLHDC9, TRAPPC1, TRAPPC4, TRAPPC3, TRAPPC2L, KHK, RHOC, SFXN5, FZR1, RHOA, DNAJB1, PLAUR, TRAPPC5, PVRL4, TRAPPC2, RORC, CDK2, PTPN7, YPEL5, CTSA, VIM, XPNPEP3 | CMTM7 | LMNA |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for GLB1_CMTM7 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for GLB1_CMTM7 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | GLB1 | C0268271 | Gangliosidosis, Generalized GM1, Type 1 (disorder) | 23 | ORPHANET;UNIPROT |
| Hgene | GLB1 | C0268272 | Gangliosidosis, Generalized GM1, Type 2 | 14 | ORPHANET;UNIPROT |
| Hgene | GLB1 | C0086652 | Mucopolysaccharidosis type IVB | 13 | ORPHANET;UNIPROT |
| Hgene | GLB1 | C0268273 | Gangliosidosis, Generalized GM1, Type 3 | 13 | ORPHANET;UNIPROT |
| Hgene | GLB1 | C0026707 | Mucopolysaccharidosis IV | 2 | CTD_human |
| Hgene | GLB1 | C0005941 | Bone Diseases, Developmental | 1 | CTD_human |
| Hgene | GLB1 | C0010038 | Corneal Opacity | 1 | CTD_human |
| Hgene | GLB1 | C0011615 | Dermatitis, Atopic | 1 | CTD_human |
| Hgene | GLB1 | C0011616 | Contact Dermatitis | 1 | CTD_human |
| Hgene | GLB1 | C0029422 | Osteochondrodysplasias | 1 | CTD_human |
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