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Fusion gene ID: 14524 |
FusionGeneSummary for GDA_FAM69B |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: GDA_FAM69B | Fusion gene ID: 14524 | Hgene | Tgene | Gene symbol | GDA | FAM69B | Gene ID | 9615 | 138311 |
| Gene name | guanine deaminase | family with sequence similarity 69 member B | |
| Synonyms | CYPIN|GAH|GUANASE|NEDASIN | C9orf136|pp6977 | |
| Cytomap | 9q21.13 | 9q34.3 | |
| Type of gene | protein-coding | protein-coding | |
| Description | guanine deaminasecytoplasmic PSD95 interactorguanine aminaseguanine aminohydrolasep51-nedasin | protein FAM69B | |
| Modification date | 20180523 | 20180519 | |
| UniProtAcc | Q9Y2T3 | Q5VUD6 | |
| Ensembl transtripts involved in fusion gene | ENST00000545168, ENST00000376989, ENST00000238018, ENST00000376986, ENST00000358399, ENST00000477618, | ENST00000371692, ENST00000371691, | |
| Fusion gene scores | * DoF score | 5 X 5 X 4=100 | 3 X 2 X 2=12 |
| # samples | 5 | 3 | |
| ** MAII score | log2(5/100*10)=-1 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(3/12*10)=1.32192809488736 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
| Context | PubMed: GDA [Title/Abstract] AND FAM69B [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | LIHC | TCGA-G3-A7M7-01A | GDA | chr9 | 74764598 | + | FAM69B | chr9 | 139612029 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| intron-3CDS | ENST00000545168 | ENST00000371692 | GDA | chr9 | 74764598 | + | FAM69B | chr9 | 139612029 | + |
| intron-intron | ENST00000545168 | ENST00000371691 | GDA | chr9 | 74764598 | + | FAM69B | chr9 | 139612029 | + |
| In-frame | ENST00000376989 | ENST00000371692 | GDA | chr9 | 74764598 | + | FAM69B | chr9 | 139612029 | + |
| 5CDS-intron | ENST00000376989 | ENST00000371691 | GDA | chr9 | 74764598 | + | FAM69B | chr9 | 139612029 | + |
| In-frame | ENST00000238018 | ENST00000371692 | GDA | chr9 | 74764598 | + | FAM69B | chr9 | 139612029 | + |
| 5CDS-intron | ENST00000238018 | ENST00000371691 | GDA | chr9 | 74764598 | + | FAM69B | chr9 | 139612029 | + |
| Frame-shift | ENST00000376986 | ENST00000371692 | GDA | chr9 | 74764598 | + | FAM69B | chr9 | 139612029 | + |
| 5CDS-intron | ENST00000376986 | ENST00000371691 | GDA | chr9 | 74764598 | + | FAM69B | chr9 | 139612029 | + |
| In-frame | ENST00000358399 | ENST00000371692 | GDA | chr9 | 74764598 | + | FAM69B | chr9 | 139612029 | + |
| 5CDS-intron | ENST00000358399 | ENST00000371691 | GDA | chr9 | 74764598 | + | FAM69B | chr9 | 139612029 | + |
| intron-3CDS | ENST00000477618 | ENST00000371692 | GDA | chr9 | 74764598 | + | FAM69B | chr9 | 139612029 | + |
| intron-intron | ENST00000477618 | ENST00000371691 | GDA | chr9 | 74764598 | + | FAM69B | chr9 | 139612029 | + |
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FusionProtFeatures for GDA_FAM69B |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| GDA | FAM69B |
| Catalyzes the hydrolytic deamination of guanine,producing xanthine and ammonia. {ECO:0000250}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
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FusionGeneSequence for GDA_FAM69B |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_GDA_ENST00000376989_chr9_74764598_+_FAM69B_ENST00000371692_chr9_139612029_+_427aa MEVLRDHLLGVSDSGKGRLPGLRVRCIFLAWLGVFAGSWLVYVHYSSYSERCRGHVCQVVICDQYRKGIISGSVCQDLCELHMVEWRTCL SVAPGQQVYSGLWRDKDVTIKCGIEETLDSKARSDAAPRRELVLFDKPTRGTSIKEFREMTLSFLKANLGDLPSLPALVGQVLLMADFNK DNRVSLAEAKSVWALLQRNEFLLLLSLQEKEHASRLLGYCGDLYLTEGVPHGAWHAAALPPLLRPLLPPALQGALQQWLGPAWPWRAKIA IGLLEFVEELFHGSYGTFYMCETTLANVGYTATYDFKMADLQQVAPEATVRRFLQGRRCEHSTDCTYGRDCRAPCDRLMRQCKGDLIQPN >In-frame_GDA_ENST00000238018_chr9_74764598_+_FAM69B_ENST00000371692_chr9_139612029_+_452aa MCAAQMPPLAHIFRGTFVHSTWTCPMEVLRDHLLGVSDSGKGRLPGLRVRCIFLAWLGVFAGSWLVYVHYSSYSERCRGHVCQVVICDQY RKGIISGSVCQDLCELHMVEWRTCLSVAPGQQVYSGLWRDKDVTIKCGIEETLDSKARSDAAPRRELVLFDKPTRGTSIKEFREMTLSFL KANLGDLPSLPALVGQVLLMADFNKDNRVSLAEAKSVWALLQRNEFLLLLSLQEKEHASRLLGYCGDLYLTEGVPHGAWHAAALPPLLRP LLPPALQGALQQWLGPAWPWRAKIAIGLLEFVEELFHGSYGTFYMCETTLANVGYTATYDFKMADLQQVAPEATVRRFLQGRRCEHSTDC TYGRDCRAPCDRLMRQCKGDLIQPNLAKVCALLRGYLLPGAPADLREELGTQLRTCTTLSGLASQVEAHHSLVLSHLKTLLWKKISNTKY >In-frame_GDA_ENST00000358399_chr9_74764598_+_FAM69B_ENST00000371692_chr9_139612029_+_452aa MCAAQMPPLAHIFRGTFVHSTWTCPMEVLRDHLLGVSDSGKGRLPGLRVRCIFLAWLGVFAGSWLVYVHYSSYSERCRGHVCQVVICDQY RKGIISGSVCQDLCELHMVEWRTCLSVAPGQQVYSGLWRDKDVTIKCGIEETLDSKARSDAAPRRELVLFDKPTRGTSIKEFREMTLSFL KANLGDLPSLPALVGQVLLMADFNKDNRVSLAEAKSVWALLQRNEFLLLLSLQEKEHASRLLGYCGDLYLTEGVPHGAWHAAALPPLLRP LLPPALQGALQQWLGPAWPWRAKIAIGLLEFVEELFHGSYGTFYMCETTLANVGYTATYDFKMADLQQVAPEATVRRFLQGRRCEHSTDC TYGRDCRAPCDRLMRQCKGDLIQPNLAKVCALLRGYLLPGAPADLREELGTQLRTCTTLSGLASQVEAHHSLVLSHLKTLLWKKISNTKY |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_GDA_ENST00000376989_chr9_74764598_+_FAM69B_ENST00000371692_chr9_139612029_+_1281nt ATGGAGGTGCTGCGGGATCACCTCCTCGGCGTGAGCGACAGCGGCAAAGGCCGGCTCCCAGGCCTCAGGGTCCGCTGCATCTTCCTGGCC TGGCTGGGCGTCTTTGCAGGCAGCTGGCTGGTGTACGTGCACTACTCGTCCTACTCGGAGCGCTGTCGCGGCCATGTCTGCCAGGTGGTC ATTTGTGACCAGTACCGCAAGGGGATCATCTCGGGCTCCGTCTGCCAGGACCTGTGTGAGCTGCATATGGTGGAGTGGAGGACCTGCCTC TCGGTGGCCCCGGGCCAGCAGGTGTACAGCGGGCTCTGGCGGGACAAGGATGTAACCATCAAGTGTGGCATTGAGGAGACCCTCGACTCC AAGGCCCGGTCGGATGCGGCCCCCCGGCGGGAGCTGGTACTGTTTGACAAGCCCACCCGGGGCACCTCCATCAAGGAATTCCGGGAGATG ACCCTCAGCTTCCTCAAGGCGAACCTGGGAGACCTGCCTTCCCTGCCGGCGCTGGTTGGCCAGGTCCTGCTCATGGCTGACTTCAACAAG GACAACCGGGTGTCCCTGGCGGAAGCCAAGTCCGTGTGGGCCCTGCTGCAGCGTAACGAGTTCCTGCTGCTGCTGTCCCTGCAGGAGAAG GAGCACGCCTCCAGACTGCTGGGCTACTGTGGGGACCTCTACCTCACCGAGGGCGTGCCGCATGGCGCCTGGCACGCGGCCGCCCTTCCA CCCCTGTTGCGCCCACTGCTGCCGCCTGCCCTGCAGGGTGCTCTCCAGCAGTGGCTGGGGCCTGCGTGGCCTTGGCGGGCCAAGATCGCC ATCGGCCTGCTGGAGTTCGTGGAGGAGCTCTTCCACGGCTCTTACGGGACTTTCTACATGTGTGAGACCACACTGGCCAACGTGGGCTAC ACAGCCACCTACGACTTCAAGATGGCCGACCTGCAGCAGGTGGCACCCGAGGCCACCGTGCGCCGCTTCCTGCAGGGCCGCCGCTGCGAG CACAGCACCGACTGCACCTACGGGCGCGACTGCAGGGCCCCGTGTGACAGGCTCATGAGGCAGTGCAAGGGCGACCTCATCCAGCCCAAC CTGGCCAAGGTGTGCGCACTGCTACGGGGCTACCTGCTGCCTGGCGCGCCCGCCGACCTCCGCGAGGAGCTGGGCACACAGCTGCGCACC TGTACCACGCTGAGCGGGCTGGCCAGCCAGGTGGAGGCCCATCACTCGCTGGTGCTCAGCCACCTCAAGACTCTGCTCTGGAAGAAGATC >In-frame_GDA_ENST00000238018_chr9_74764598_+_FAM69B_ENST00000371692_chr9_139612029_+_1356nt ATGTGTGCCGCTCAGATGCCGCCCCTGGCGCACATCTTCCGAGGGACGTTCGTCCACTCCACCTGGACCTGCCCCATGGAGGTGCTGCGG GATCACCTCCTCGGCGTGAGCGACAGCGGCAAAGGCCGGCTCCCAGGCCTCAGGGTCCGCTGCATCTTCCTGGCCTGGCTGGGCGTCTTT GCAGGCAGCTGGCTGGTGTACGTGCACTACTCGTCCTACTCGGAGCGCTGTCGCGGCCATGTCTGCCAGGTGGTCATTTGTGACCAGTAC CGCAAGGGGATCATCTCGGGCTCCGTCTGCCAGGACCTGTGTGAGCTGCATATGGTGGAGTGGAGGACCTGCCTCTCGGTGGCCCCGGGC CAGCAGGTGTACAGCGGGCTCTGGCGGGACAAGGATGTAACCATCAAGTGTGGCATTGAGGAGACCCTCGACTCCAAGGCCCGGTCGGAT GCGGCCCCCCGGCGGGAGCTGGTACTGTTTGACAAGCCCACCCGGGGCACCTCCATCAAGGAATTCCGGGAGATGACCCTCAGCTTCCTC AAGGCGAACCTGGGAGACCTGCCTTCCCTGCCGGCGCTGGTTGGCCAGGTCCTGCTCATGGCTGACTTCAACAAGGACAACCGGGTGTCC CTGGCGGAAGCCAAGTCCGTGTGGGCCCTGCTGCAGCGTAACGAGTTCCTGCTGCTGCTGTCCCTGCAGGAGAAGGAGCACGCCTCCAGA CTGCTGGGCTACTGTGGGGACCTCTACCTCACCGAGGGCGTGCCGCATGGCGCCTGGCACGCGGCCGCCCTTCCACCCCTGTTGCGCCCA CTGCTGCCGCCTGCCCTGCAGGGTGCTCTCCAGCAGTGGCTGGGGCCTGCGTGGCCTTGGCGGGCCAAGATCGCCATCGGCCTGCTGGAG TTCGTGGAGGAGCTCTTCCACGGCTCTTACGGGACTTTCTACATGTGTGAGACCACACTGGCCAACGTGGGCTACACAGCCACCTACGAC TTCAAGATGGCCGACCTGCAGCAGGTGGCACCCGAGGCCACCGTGCGCCGCTTCCTGCAGGGCCGCCGCTGCGAGCACAGCACCGACTGC ACCTACGGGCGCGACTGCAGGGCCCCGTGTGACAGGCTCATGAGGCAGTGCAAGGGCGACCTCATCCAGCCCAACCTGGCCAAGGTGTGC GCACTGCTACGGGGCTACCTGCTGCCTGGCGCGCCCGCCGACCTCCGCGAGGAGCTGGGCACACAGCTGCGCACCTGTACCACGCTGAGC GGGCTGGCCAGCCAGGTGGAGGCCCATCACTCGCTGGTGCTCAGCCACCTCAAGACTCTGCTCTGGAAGAAGATCTCCAACACCAAGTAC >In-frame_GDA_ENST00000358399_chr9_74764598_+_FAM69B_ENST00000371692_chr9_139612029_+_1356nt ATGTGTGCCGCTCAGATGCCGCCCCTGGCGCACATCTTCCGAGGGACGTTCGTCCACTCCACCTGGACCTGCCCCATGGAGGTGCTGCGG GATCACCTCCTCGGCGTGAGCGACAGCGGCAAAGGCCGGCTCCCAGGCCTCAGGGTCCGCTGCATCTTCCTGGCCTGGCTGGGCGTCTTT GCAGGCAGCTGGCTGGTGTACGTGCACTACTCGTCCTACTCGGAGCGCTGTCGCGGCCATGTCTGCCAGGTGGTCATTTGTGACCAGTAC CGCAAGGGGATCATCTCGGGCTCCGTCTGCCAGGACCTGTGTGAGCTGCATATGGTGGAGTGGAGGACCTGCCTCTCGGTGGCCCCGGGC CAGCAGGTGTACAGCGGGCTCTGGCGGGACAAGGATGTAACCATCAAGTGTGGCATTGAGGAGACCCTCGACTCCAAGGCCCGGTCGGAT GCGGCCCCCCGGCGGGAGCTGGTACTGTTTGACAAGCCCACCCGGGGCACCTCCATCAAGGAATTCCGGGAGATGACCCTCAGCTTCCTC AAGGCGAACCTGGGAGACCTGCCTTCCCTGCCGGCGCTGGTTGGCCAGGTCCTGCTCATGGCTGACTTCAACAAGGACAACCGGGTGTCC CTGGCGGAAGCCAAGTCCGTGTGGGCCCTGCTGCAGCGTAACGAGTTCCTGCTGCTGCTGTCCCTGCAGGAGAAGGAGCACGCCTCCAGA CTGCTGGGCTACTGTGGGGACCTCTACCTCACCGAGGGCGTGCCGCATGGCGCCTGGCACGCGGCCGCCCTTCCACCCCTGTTGCGCCCA CTGCTGCCGCCTGCCCTGCAGGGTGCTCTCCAGCAGTGGCTGGGGCCTGCGTGGCCTTGGCGGGCCAAGATCGCCATCGGCCTGCTGGAG TTCGTGGAGGAGCTCTTCCACGGCTCTTACGGGACTTTCTACATGTGTGAGACCACACTGGCCAACGTGGGCTACACAGCCACCTACGAC TTCAAGATGGCCGACCTGCAGCAGGTGGCACCCGAGGCCACCGTGCGCCGCTTCCTGCAGGGCCGCCGCTGCGAGCACAGCACCGACTGC ACCTACGGGCGCGACTGCAGGGCCCCGTGTGACAGGCTCATGAGGCAGTGCAAGGGCGACCTCATCCAGCCCAACCTGGCCAAGGTGTGC GCACTGCTACGGGGCTACCTGCTGCCTGGCGCGCCCGCCGACCTCCGCGAGGAGCTGGGCACACAGCTGCGCACCTGTACCACGCTGAGC GGGCTGGCCAGCCAGGTGGAGGCCCATCACTCGCTGGTGCTCAGCCACCTCAAGACTCTGCTCTGGAAGAAGATCTCCAACACCAAGTAC |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_GDA_ENST00000376989_chr9_74764598_+_FAM69B_ENST00000371692_chr9_139612029_+_1815nt GTAGGGAGCCAGCCCCTGGGCGCGGCCTGCAGGGTACCGGCAACCGCCCGGGTAAGCGGGGGCAGGACAAGGCCGGAGCCTGTGTCCGCC CGGCAGCCGCCCGCAGCTGCAGAGAGTCCCGCTGCGTCTCCGCCGCGTGCGCCCTCCTCGACCAGCAGACCCGCGCTGCGCTCCGCCGCT GACATGTGTGCCGCTCAGATGCCGCCCCTGGCGCACATCTTCCGAGGGACGTTCGTCCACTCCACCTGGACCTGCCCCATGGAGGTGCTG CGGGATCACCTCCTCGGCGTGAGCGACAGCGGCAAAGGCCGGCTCCCAGGCCTCAGGGTCCGCTGCATCTTCCTGGCCTGGCTGGGCGTC TTTGCAGGCAGCTGGCTGGTGTACGTGCACTACTCGTCCTACTCGGAGCGCTGTCGCGGCCATGTCTGCCAGGTGGTCATTTGTGACCAG TACCGCAAGGGGATCATCTCGGGCTCCGTCTGCCAGGACCTGTGTGAGCTGCATATGGTGGAGTGGAGGACCTGCCTCTCGGTGGCCCCG GGCCAGCAGGTGTACAGCGGGCTCTGGCGGGACAAGGATGTAACCATCAAGTGTGGCATTGAGGAGACCCTCGACTCCAAGGCCCGGTCG GATGCGGCCCCCCGGCGGGAGCTGGTACTGTTTGACAAGCCCACCCGGGGCACCTCCATCAAGGAATTCCGGGAGATGACCCTCAGCTTC CTCAAGGCGAACCTGGGAGACCTGCCTTCCCTGCCGGCGCTGGTTGGCCAGGTCCTGCTCATGGCTGACTTCAACAAGGACAACCGGGTG TCCCTGGCGGAAGCCAAGTCCGTGTGGGCCCTGCTGCAGCGTAACGAGTTCCTGCTGCTGCTGTCCCTGCAGGAGAAGGAGCACGCCTCC AGACTGCTGGGCTACTGTGGGGACCTCTACCTCACCGAGGGCGTGCCGCATGGCGCCTGGCACGCGGCCGCCCTTCCACCCCTGTTGCGC CCACTGCTGCCGCCTGCCCTGCAGGGTGCTCTCCAGCAGTGGCTGGGGCCTGCGTGGCCTTGGCGGGCCAAGATCGCCATCGGCCTGCTG GAGTTCGTGGAGGAGCTCTTCCACGGCTCTTACGGGACTTTCTACATGTGTGAGACCACACTGGCCAACGTGGGCTACACAGCCACCTAC GACTTCAAGATGGCCGACCTGCAGCAGGTGGCACCCGAGGCCACCGTGCGCCGCTTCCTGCAGGGCCGCCGCTGCGAGCACAGCACCGAC TGCACCTACGGGCGCGACTGCAGGGCCCCGTGTGACAGGCTCATGAGGCAGTGCAAGGGCGACCTCATCCAGCCCAACCTGGCCAAGGTG TGCGCACTGCTACGGGGCTACCTGCTGCCTGGCGCGCCCGCCGACCTCCGCGAGGAGCTGGGCACACAGCTGCGCACCTGTACCACGCTG AGCGGGCTGGCCAGCCAGGTGGAGGCCCATCACTCGCTGGTGCTCAGCCACCTCAAGACTCTGCTCTGGAAGAAGATCTCCAACACCAAG TACTCTTGATGGGGCAGTGAGGGGCCTGGCCACCCTTCCTGGAGCTGGCCAGGTGCCAGGGTCCAACCCTCCCTCAAGGAATCCTGTCAG AAGATGTGAAATGCAACTGTGTTGCAAAATCACTCCCCTACCGTCAGGGCTCTGGATTCCAGCACCACAGACATGAGACCCCAGCTCGGA GCAAAGGCGGACATGGACATCCCGGCAGGAGAGTCCTCCAAGGGGGTTTGTTACTCTGAAGAACGTAATGTCAATAAACAGCTTTTATGT >In-frame_GDA_ENST00000238018_chr9_74764598_+_FAM69B_ENST00000371692_chr9_139612029_+_1815nt GTAGGGAGCCAGCCCCTGGGCGCGGCCTGCAGGGTACCGGCAACCGCCCGGGTAAGCGGGGGCAGGACAAGGCCGGAGCCTGTGTCCGCC CGGCAGCCGCCCGCAGCTGCAGAGAGTCCCGCTGCGTCTCCGCCGCGTGCGCCCTCCTCGACCAGCAGACCCGCGCTGCGCTCCGCCGCT GACATGTGTGCCGCTCAGATGCCGCCCCTGGCGCACATCTTCCGAGGGACGTTCGTCCACTCCACCTGGACCTGCCCCATGGAGGTGCTG CGGGATCACCTCCTCGGCGTGAGCGACAGCGGCAAAGGCCGGCTCCCAGGCCTCAGGGTCCGCTGCATCTTCCTGGCCTGGCTGGGCGTC TTTGCAGGCAGCTGGCTGGTGTACGTGCACTACTCGTCCTACTCGGAGCGCTGTCGCGGCCATGTCTGCCAGGTGGTCATTTGTGACCAG TACCGCAAGGGGATCATCTCGGGCTCCGTCTGCCAGGACCTGTGTGAGCTGCATATGGTGGAGTGGAGGACCTGCCTCTCGGTGGCCCCG GGCCAGCAGGTGTACAGCGGGCTCTGGCGGGACAAGGATGTAACCATCAAGTGTGGCATTGAGGAGACCCTCGACTCCAAGGCCCGGTCG GATGCGGCCCCCCGGCGGGAGCTGGTACTGTTTGACAAGCCCACCCGGGGCACCTCCATCAAGGAATTCCGGGAGATGACCCTCAGCTTC CTCAAGGCGAACCTGGGAGACCTGCCTTCCCTGCCGGCGCTGGTTGGCCAGGTCCTGCTCATGGCTGACTTCAACAAGGACAACCGGGTG TCCCTGGCGGAAGCCAAGTCCGTGTGGGCCCTGCTGCAGCGTAACGAGTTCCTGCTGCTGCTGTCCCTGCAGGAGAAGGAGCACGCCTCC AGACTGCTGGGCTACTGTGGGGACCTCTACCTCACCGAGGGCGTGCCGCATGGCGCCTGGCACGCGGCCGCCCTTCCACCCCTGTTGCGC CCACTGCTGCCGCCTGCCCTGCAGGGTGCTCTCCAGCAGTGGCTGGGGCCTGCGTGGCCTTGGCGGGCCAAGATCGCCATCGGCCTGCTG GAGTTCGTGGAGGAGCTCTTCCACGGCTCTTACGGGACTTTCTACATGTGTGAGACCACACTGGCCAACGTGGGCTACACAGCCACCTAC GACTTCAAGATGGCCGACCTGCAGCAGGTGGCACCCGAGGCCACCGTGCGCCGCTTCCTGCAGGGCCGCCGCTGCGAGCACAGCACCGAC TGCACCTACGGGCGCGACTGCAGGGCCCCGTGTGACAGGCTCATGAGGCAGTGCAAGGGCGACCTCATCCAGCCCAACCTGGCCAAGGTG TGCGCACTGCTACGGGGCTACCTGCTGCCTGGCGCGCCCGCCGACCTCCGCGAGGAGCTGGGCACACAGCTGCGCACCTGTACCACGCTG AGCGGGCTGGCCAGCCAGGTGGAGGCCCATCACTCGCTGGTGCTCAGCCACCTCAAGACTCTGCTCTGGAAGAAGATCTCCAACACCAAG TACTCTTGATGGGGCAGTGAGGGGCCTGGCCACCCTTCCTGGAGCTGGCCAGGTGCCAGGGTCCAACCCTCCCTCAAGGAATCCTGTCAG AAGATGTGAAATGCAACTGTGTTGCAAAATCACTCCCCTACCGTCAGGGCTCTGGATTCCAGCACCACAGACATGAGACCCCAGCTCGGA GCAAAGGCGGACATGGACATCCCGGCAGGAGAGTCCTCCAAGGGGGTTTGTTACTCTGAAGAACGTAATGTCAATAAACAGCTTTTATGT >In-frame_GDA_ENST00000358399_chr9_74764598_+_FAM69B_ENST00000371692_chr9_139612029_+_1725nt CGGCAGCCGCCCGCAGCTGCAGAGAGTCCCGCTGCGTCTCCGCCGCGTGCGCCCTCCTCGACCAGCAGACCCGCGCTGCGCTCCGCCGCT GACATGTGTGCCGCTCAGATGCCGCCCCTGGCGCACATCTTCCGAGGGACGTTCGTCCACTCCACCTGGACCTGCCCCATGGAGGTGCTG CGGGATCACCTCCTCGGCGTGAGCGACAGCGGCAAAGGCCGGCTCCCAGGCCTCAGGGTCCGCTGCATCTTCCTGGCCTGGCTGGGCGTC TTTGCAGGCAGCTGGCTGGTGTACGTGCACTACTCGTCCTACTCGGAGCGCTGTCGCGGCCATGTCTGCCAGGTGGTCATTTGTGACCAG TACCGCAAGGGGATCATCTCGGGCTCCGTCTGCCAGGACCTGTGTGAGCTGCATATGGTGGAGTGGAGGACCTGCCTCTCGGTGGCCCCG GGCCAGCAGGTGTACAGCGGGCTCTGGCGGGACAAGGATGTAACCATCAAGTGTGGCATTGAGGAGACCCTCGACTCCAAGGCCCGGTCG GATGCGGCCCCCCGGCGGGAGCTGGTACTGTTTGACAAGCCCACCCGGGGCACCTCCATCAAGGAATTCCGGGAGATGACCCTCAGCTTC CTCAAGGCGAACCTGGGAGACCTGCCTTCCCTGCCGGCGCTGGTTGGCCAGGTCCTGCTCATGGCTGACTTCAACAAGGACAACCGGGTG TCCCTGGCGGAAGCCAAGTCCGTGTGGGCCCTGCTGCAGCGTAACGAGTTCCTGCTGCTGCTGTCCCTGCAGGAGAAGGAGCACGCCTCC AGACTGCTGGGCTACTGTGGGGACCTCTACCTCACCGAGGGCGTGCCGCATGGCGCCTGGCACGCGGCCGCCCTTCCACCCCTGTTGCGC CCACTGCTGCCGCCTGCCCTGCAGGGTGCTCTCCAGCAGTGGCTGGGGCCTGCGTGGCCTTGGCGGGCCAAGATCGCCATCGGCCTGCTG GAGTTCGTGGAGGAGCTCTTCCACGGCTCTTACGGGACTTTCTACATGTGTGAGACCACACTGGCCAACGTGGGCTACACAGCCACCTAC GACTTCAAGATGGCCGACCTGCAGCAGGTGGCACCCGAGGCCACCGTGCGCCGCTTCCTGCAGGGCCGCCGCTGCGAGCACAGCACCGAC TGCACCTACGGGCGCGACTGCAGGGCCCCGTGTGACAGGCTCATGAGGCAGTGCAAGGGCGACCTCATCCAGCCCAACCTGGCCAAGGTG TGCGCACTGCTACGGGGCTACCTGCTGCCTGGCGCGCCCGCCGACCTCCGCGAGGAGCTGGGCACACAGCTGCGCACCTGTACCACGCTG AGCGGGCTGGCCAGCCAGGTGGAGGCCCATCACTCGCTGGTGCTCAGCCACCTCAAGACTCTGCTCTGGAAGAAGATCTCCAACACCAAG TACTCTTGATGGGGCAGTGAGGGGCCTGGCCACCCTTCCTGGAGCTGGCCAGGTGCCAGGGTCCAACCCTCCCTCAAGGAATCCTGTCAG AAGATGTGAAATGCAACTGTGTTGCAAAATCACTCCCCTACCGTCAGGGCTCTGGATTCCAGCACCACAGACATGAGACCCCAGCTCGGA GCAAAGGCGGACATGGACATCCCGGCAGGAGAGTCCTCCAAGGGGGTTTGTTACTCTGAAGAACGTAATGTCAATAAACAGCTTTTATGT |
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FusionGenePPI for GDA_FAM69B |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| GDA | DLG3, AKT1, SNTA1, BCCIP, EIF5A, CSE1L, GNS, PEPD, SORD, GLS, HSPD1, KYNU, LDHAL6B, MVD, NAGK, RPS6KA3, SLC9A3R1, C11orf58, SMS, ABAT, AMDHD1, AP1G1, ATRIP, FAHD1, ASNS, CIAPIN1, LARS, LCMT2, NPEPL1, TIPRL, UBA1, MCM2, DTX3, C7orf31, MATN3, HERC3 | FAM69B | RBMS2, CAND1, SAT1, HTR3C, TCTN2 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for GDA_FAM69B |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for GDA_FAM69B |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | GDA | C0024667 | Animal Mammary Neoplasms | 1 | CTD_human |
| Hgene | GDA | C0024668 | Mammary Neoplasms, Experimental | 1 | CTD_human |
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