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Fusion gene ID: 14286 |
FusionGeneSummary for GALNT11_CNTNAP2 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: GALNT11_CNTNAP2 | Fusion gene ID: 14286 | Hgene | Tgene | Gene symbol | GALNT11 | CNTNAP2 | Gene ID | 63917 | 26047 |
| Gene name | polypeptide N-acetylgalactosaminyltransferase 11 | contactin associated protein like 2 | |
| Synonyms | GALNAC-T11|GALNACT11 | AUTS15|CASPR2|CDFE|NRXN4|PTHSL1 | |
| Cytomap | 7q36.1|7q36.1 | 7q35-q36.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | polypeptide N-acetylgalactosaminyltransferase 11UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 11UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 11 (GalNAc-T11)polypeptide GalNAc transferase 11pp-GaNTase 11p | contactin-associated protein-like 2cell recognition molecule Caspr2homolog of Drosophila neurexin IV | |
| Modification date | 20180523 | 20180519 | |
| UniProtAcc | Q8NCW6 | Q9UHC6 | |
| Ensembl transtripts involved in fusion gene | ENST00000482812, ENST00000430044, ENST00000452146, ENST00000434507, ENST00000415421, ENST00000320311, ENST00000422997, | ENST00000361727, ENST00000538075, ENST00000463592, | |
| Fusion gene scores | * DoF score | 11 X 5 X 8=440 | 8 X 8 X 7=448 |
| # samples | 12 | 9 | |
| ** MAII score | log2(12/440*10)=-1.87446911791614 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(9/448*10)=-2.31550182572793 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: GALNT11 [Title/Abstract] AND CNTNAP2 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | GALNT11 | GO:0018243 | protein O-linked glycosylation via threonine | 24226769 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | CESC | TCGA-ZJ-AAXB-01A | GALNT11 | chr7 | 151722969 | + | CNTNAP2 | chr7 | 147259230 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 3UTR-3CDS | ENST00000482812 | ENST00000361727 | GALNT11 | chr7 | 151722969 | + | CNTNAP2 | chr7 | 147259230 | + |
| 3UTR-intron | ENST00000482812 | ENST00000538075 | GALNT11 | chr7 | 151722969 | + | CNTNAP2 | chr7 | 147259230 | + |
| 3UTR-intron | ENST00000482812 | ENST00000463592 | GALNT11 | chr7 | 151722969 | + | CNTNAP2 | chr7 | 147259230 | + |
| 5UTR-3CDS | ENST00000430044 | ENST00000361727 | GALNT11 | chr7 | 151722969 | + | CNTNAP2 | chr7 | 147259230 | + |
| 5UTR-intron | ENST00000430044 | ENST00000538075 | GALNT11 | chr7 | 151722969 | + | CNTNAP2 | chr7 | 147259230 | + |
| 5UTR-intron | ENST00000430044 | ENST00000463592 | GALNT11 | chr7 | 151722969 | + | CNTNAP2 | chr7 | 147259230 | + |
| In-frame | ENST00000452146 | ENST00000361727 | GALNT11 | chr7 | 151722969 | + | CNTNAP2 | chr7 | 147259230 | + |
| 5CDS-intron | ENST00000452146 | ENST00000538075 | GALNT11 | chr7 | 151722969 | + | CNTNAP2 | chr7 | 147259230 | + |
| 5CDS-intron | ENST00000452146 | ENST00000463592 | GALNT11 | chr7 | 151722969 | + | CNTNAP2 | chr7 | 147259230 | + |
| intron-3CDS | ENST00000434507 | ENST00000361727 | GALNT11 | chr7 | 151722969 | + | CNTNAP2 | chr7 | 147259230 | + |
| intron-intron | ENST00000434507 | ENST00000538075 | GALNT11 | chr7 | 151722969 | + | CNTNAP2 | chr7 | 147259230 | + |
| intron-intron | ENST00000434507 | ENST00000463592 | GALNT11 | chr7 | 151722969 | + | CNTNAP2 | chr7 | 147259230 | + |
| intron-3CDS | ENST00000415421 | ENST00000361727 | GALNT11 | chr7 | 151722969 | + | CNTNAP2 | chr7 | 147259230 | + |
| intron-intron | ENST00000415421 | ENST00000538075 | GALNT11 | chr7 | 151722969 | + | CNTNAP2 | chr7 | 147259230 | + |
| intron-intron | ENST00000415421 | ENST00000463592 | GALNT11 | chr7 | 151722969 | + | CNTNAP2 | chr7 | 147259230 | + |
| intron-3CDS | ENST00000320311 | ENST00000361727 | GALNT11 | chr7 | 151722969 | + | CNTNAP2 | chr7 | 147259230 | + |
| intron-intron | ENST00000320311 | ENST00000538075 | GALNT11 | chr7 | 151722969 | + | CNTNAP2 | chr7 | 147259230 | + |
| intron-intron | ENST00000320311 | ENST00000463592 | GALNT11 | chr7 | 151722969 | + | CNTNAP2 | chr7 | 147259230 | + |
| intron-3CDS | ENST00000422997 | ENST00000361727 | GALNT11 | chr7 | 151722969 | + | CNTNAP2 | chr7 | 147259230 | + |
| intron-intron | ENST00000422997 | ENST00000538075 | GALNT11 | chr7 | 151722969 | + | CNTNAP2 | chr7 | 147259230 | + |
| intron-intron | ENST00000422997 | ENST00000463592 | GALNT11 | chr7 | 151722969 | + | CNTNAP2 | chr7 | 147259230 | + |
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FusionProtFeatures for GALNT11_CNTNAP2 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| GALNT11 | CNTNAP2 |
| Polypeptide N-acetylgalactosaminyltransferase thatcatalyzes the initiation of protein O-linked glycosylation and isinvolved in left/right asymmetry by mediating O-glycosylation ofNOTCH1. O-glycosylation of NOTCH1 promotes activation of NOTCH1,modulating the balance between motile and immotile (sensory) ciliaat the left-right organiser (LRO). Polypeptide N-acetylgalactosaminyltransferases catalyze the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue onthe protein receptor. Displays the same enzyme activity towardMUC1, MUC4, and EA2 than GALNT1. Not involved in glycosylation oferythropoietin (EPO). {ECO:0000269|PubMed:11925450,ECO:0000269|PubMed:24226769}. | Required, with CNTNAP1, for radial and longitudinalorganization of myelinated axons. Plays a role in the formation offunctional distinct domains critical for saltatory conduction ofnerve impulses in myelinated nerve fibers. Demarcates thejuxtaparanodal region of the axo-glial junction.{ECO:0000250|UniProtKB:Q9CPW0}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
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FusionGeneSequence for GALNT11_CNTNAP2 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_GALNT11_ENST00000452146_chr7_151722969_+_CNTNAP2_ENST00000361727_chr7_147259230_+_757aa MPQPESQKAAILGCGQGAIYEPSCEAYKHLGQTSNYYWIDPDGSGPLGPLKVYCNMTEDKVWTIVSHDLQMQTPVVGYNPEKYSVTQLVY SASMDQISAITDSAEYCEQYVSYFCKMSRLLNTPDGSPYTWWVGKANEKHYYWGGSGPGIQKCACGIERNCTDPKYYCNCDADYKQWRKD AGFLSYKDHLPVSQVVVGDTDRQGSEAKLSVGPLRCQGDRNYWNAASFPNPSSYLHFSTFQGETSADISFYFKTLTPWGVFLENMGKEDF IKLELKSATEVSFSFDVGNGPVEIVVRSPTPLNDDQWHRVTAERNVKQASLQVDRLPQQIRKAPTEGHTRLELYSQLFVGGAGGQQGFLG CIRSLRMNGVTLDLEERAKVTSGFISGCSGHCTSYGTNCENGGKCLERYHGYSCDCSNTAYDGTFCNKDVGAFFEEGMWLRYNFQAPATN ARDSSSRVDNAPDQQNSHPDLAQEEIRFSFSTTKAPCILLYISSFTTDFLAVLVKPTGSLQIRYNLGGTREPYNIDVDHRNMANGQPHSV NITRHEKTIFLKLDHYPSVSYHLPSSSDTLFNSPKSLFLGKVIETGKIDQEIHKYNTPGFTGCLSRVQFNQIAPLKAALRQTNASAHVHI QGELVESNCGASPLTLSPMSSATDPWHLDHLDSASADFPYNPGQGQAIRNGVNRNSAIIGGVIAVVIFTILCTLVFLIRYMFRHKGTYHT |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_GALNT11_ENST00000452146_chr7_151722969_+_CNTNAP2_ENST00000361727_chr7_147259230_+_2271nt ATGCCGCAGCCCGAGTCCCAGAAGGCGGCGATCCTGGGCTGCGGGCAAGGCGCTATCTACGAGCCTTCCTGTGAAGCCTACAAACACCTA GGACAGACATCAAATTATTACTGGATAGATCCTGATGGCAGCGGACCTCTGGGGCCTCTGAAAGTTTACTGCAACATGACAGAGGACAAA GTGTGGACCATAGTGTCTCATGACTTGCAGATGCAGACGCCTGTGGTCGGCTACAACCCAGAAAAATACTCAGTGACACAGCTCGTTTAC AGCGCCTCCATGGACCAGATAAGTGCCATCACTGACAGTGCCGAGTACTGCGAGCAGTATGTCTCCTATTTCTGCAAGATGTCAAGATTG TTGAACACCCCAGATGGAAGCCCTTACACTTGGTGGGTTGGCAAAGCCAACGAGAAGCACTACTACTGGGGAGGCTCTGGGCCTGGAATC CAGAAATGTGCCTGCGGCATCGAACGCAACTGCACAGATCCCAAGTACTACTGTAACTGCGACGCGGACTACAAGCAATGGAGGAAGGAT GCTGGTTTCTTATCATACAAAGATCACCTGCCAGTGAGCCAAGTGGTGGTTGGAGATACTGACCGTCAAGGCTCAGAAGCCAAATTGAGC GTAGGTCCTCTGCGCTGCCAAGGAGACAGGAATTATTGGAATGCCGCCTCTTTCCCAAACCCATCCTCCTACCTGCACTTCTCTACTTTC CAAGGGGAAACTAGCGCTGACATTTCTTTCTACTTCAAAACATTAACCCCCTGGGGAGTGTTTCTTGAAAATATGGGAAAGGAAGATTTC ATCAAGCTGGAGCTGAAGTCTGCCACAGAAGTGTCCTTTTCATTTGATGTGGGAAATGGGCCAGTAGAGATTGTAGTGAGGTCACCAACC CCTCTCAACGATGACCAGTGGCACCGGGTCACTGCAGAGAGGAATGTCAAGCAGGCCAGCCTACAGGTGGACCGGCTACCGCAGCAGATC CGCAAGGCCCCAACAGAAGGCCACACCCGCCTGGAGCTCTACAGCCAGTTATTTGTGGGTGGTGCTGGGGGCCAGCAGGGCTTCCTGGGC TGCATCCGCTCCTTGAGGATGAATGGGGTGACACTTGACCTGGAGGAAAGAGCAAAGGTCACATCTGGGTTCATATCCGGATGCTCGGGC CATTGCACCAGCTATGGAACAAACTGTGAAAATGGAGGCAAATGCCTAGAGAGATACCACGGTTACTCCTGCGATTGCTCTAATACTGCA TATGATGGAACATTTTGCAACAAAGATGTTGGTGCATTTTTTGAAGAAGGGATGTGGCTACGATATAACTTTCAGGCACCAGCAACAAAT GCCAGAGACTCCAGCAGCAGAGTAGACAACGCTCCCGACCAGCAGAACTCCCACCCGGACCTGGCACAGGAGGAGATCCGCTTCAGCTTC AGCACCACCAAGGCGCCCTGCATTCTCCTCTACATCAGCTCCTTCACCACAGACTTCTTGGCAGTCCTCGTCAAACCCACTGGAAGCTTA CAGATTCGATACAACCTGGGTGGCACCCGAGAGCCATACAATATTGACGTAGACCACAGGAACATGGCCAATGGACAGCCCCACAGTGTC AACATCACCCGCCACGAGAAGACCATCTTTCTCAAGCTCGATCATTATCCTTCTGTGAGTTACCATCTGCCAAGTTCATCCGACACCCTC TTCAATTCTCCCAAGTCGCTCTTTCTGGGAAAAGTTATAGAAACAGGGAAAATTGACCAAGAGATTCACAAATACAACACCCCAGGATTC ACTGGTTGCCTCTCCAGAGTCCAGTTCAACCAGATCGCCCCTCTCAAGGCCGCCTTGAGGCAGACAAACGCCTCGGCTCACGTCCACATC CAGGGCGAGCTGGTGGAGTCCAACTGCGGGGCCTCGCCGCTGACCCTCTCCCCCATGTCGTCCGCCACCGACCCCTGGCACCTGGATCAC CTGGATTCAGCCAGTGCGGATTTTCCATATAATCCAGGACAAGGCCAAGCTATAAGAAATGGAGTCAACAGAAACTCGGCTATCATTGGA GGCGTCATTGCTGTGGTGATTTTCACCATCCTGTGCACCCTGGTCTTCCTGATCCGGTACATGTTCCGCCACAAGGGCACCTACCATACC AACGAAGCAAAGGGGGCGGAGTCGGCAGAGAGCGCGGACGCCGCCATCATGAACAACGACCCCAACTTCACAGAGACCATTGATGAAAGC |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_GALNT11_ENST00000452146_chr7_151722969_+_CNTNAP2_ENST00000361727_chr7_147259230_+_7735nt GCGACGCCTGGCTGCTGGGCCCCGGGGCAGTTCAGCCCGCGCCGCTCCTGCGGGTCGGACTGGGGCTGTGGCGGGAGAGAAGATGCCGCA GCCCGAGTCCCAGAAGGCGGCGATCCTGGGCTGCGGGCAAGGCGCTATCTACGAGCCTTCCTGTGAAGCCTACAAACACCTAGGACAGAC ATCAAATTATTACTGGATAGATCCTGATGGCAGCGGACCTCTGGGGCCTCTGAAAGTTTACTGCAACATGACAGAGGACAAAGTGTGGAC CATAGTGTCTCATGACTTGCAGATGCAGACGCCTGTGGTCGGCTACAACCCAGAAAAATACTCAGTGACACAGCTCGTTTACAGCGCCTC CATGGACCAGATAAGTGCCATCACTGACAGTGCCGAGTACTGCGAGCAGTATGTCTCCTATTTCTGCAAGATGTCAAGATTGTTGAACAC CCCAGATGGAAGCCCTTACACTTGGTGGGTTGGCAAAGCCAACGAGAAGCACTACTACTGGGGAGGCTCTGGGCCTGGAATCCAGAAATG TGCCTGCGGCATCGAACGCAACTGCACAGATCCCAAGTACTACTGTAACTGCGACGCGGACTACAAGCAATGGAGGAAGGATGCTGGTTT CTTATCATACAAAGATCACCTGCCAGTGAGCCAAGTGGTGGTTGGAGATACTGACCGTCAAGGCTCAGAAGCCAAATTGAGCGTAGGTCC TCTGCGCTGCCAAGGAGACAGGAATTATTGGAATGCCGCCTCTTTCCCAAACCCATCCTCCTACCTGCACTTCTCTACTTTCCAAGGGGA AACTAGCGCTGACATTTCTTTCTACTTCAAAACATTAACCCCCTGGGGAGTGTTTCTTGAAAATATGGGAAAGGAAGATTTCATCAAGCT GGAGCTGAAGTCTGCCACAGAAGTGTCCTTTTCATTTGATGTGGGAAATGGGCCAGTAGAGATTGTAGTGAGGTCACCAACCCCTCTCAA CGATGACCAGTGGCACCGGGTCACTGCAGAGAGGAATGTCAAGCAGGCCAGCCTACAGGTGGACCGGCTACCGCAGCAGATCCGCAAGGC CCCAACAGAAGGCCACACCCGCCTGGAGCTCTACAGCCAGTTATTTGTGGGTGGTGCTGGGGGCCAGCAGGGCTTCCTGGGCTGCATCCG CTCCTTGAGGATGAATGGGGTGACACTTGACCTGGAGGAAAGAGCAAAGGTCACATCTGGGTTCATATCCGGATGCTCGGGCCATTGCAC CAGCTATGGAACAAACTGTGAAAATGGAGGCAAATGCCTAGAGAGATACCACGGTTACTCCTGCGATTGCTCTAATACTGCATATGATGG AACATTTTGCAACAAAGATGTTGGTGCATTTTTTGAAGAAGGGATGTGGCTACGATATAACTTTCAGGCACCAGCAACAAATGCCAGAGA CTCCAGCAGCAGAGTAGACAACGCTCCCGACCAGCAGAACTCCCACCCGGACCTGGCACAGGAGGAGATCCGCTTCAGCTTCAGCACCAC CAAGGCGCCCTGCATTCTCCTCTACATCAGCTCCTTCACCACAGACTTCTTGGCAGTCCTCGTCAAACCCACTGGAAGCTTACAGATTCG ATACAACCTGGGTGGCACCCGAGAGCCATACAATATTGACGTAGACCACAGGAACATGGCCAATGGACAGCCCCACAGTGTCAACATCAC CCGCCACGAGAAGACCATCTTTCTCAAGCTCGATCATTATCCTTCTGTGAGTTACCATCTGCCAAGTTCATCCGACACCCTCTTCAATTC TCCCAAGTCGCTCTTTCTGGGAAAAGTTATAGAAACAGGGAAAATTGACCAAGAGATTCACAAATACAACACCCCAGGATTCACTGGTTG CCTCTCCAGAGTCCAGTTCAACCAGATCGCCCCTCTCAAGGCCGCCTTGAGGCAGACAAACGCCTCGGCTCACGTCCACATCCAGGGCGA GCTGGTGGAGTCCAACTGCGGGGCCTCGCCGCTGACCCTCTCCCCCATGTCGTCCGCCACCGACCCCTGGCACCTGGATCACCTGGATTC AGCCAGTGCGGATTTTCCATATAATCCAGGACAAGGCCAAGCTATAAGAAATGGAGTCAACAGAAACTCGGCTATCATTGGAGGCGTCAT TGCTGTGGTGATTTTCACCATCCTGTGCACCCTGGTCTTCCTGATCCGGTACATGTTCCGCCACAAGGGCACCTACCATACCAACGAAGC AAAGGGGGCGGAGTCGGCAGAGAGCGCGGACGCCGCCATCATGAACAACGACCCCAACTTCACAGAGACCATTGATGAAAGCAAAAAGGA ATGGCTCATTTGAGGGGTGGCTACTTGGCTATGGGATAGGGAGGAGGGAATTACTAGGGAGGAGAGAAAGGGACAAAAGCACCCTGCTTC ATACTCTTGAGCACATCCTTAAAATATCAGCACAAGTTGGGGGAGGCAGGCAATGGAATATAATGGAATATTCTTGAGACTGATCACAAA AAAAAAAACCTTTTTAATATTTCTTTATAGCTGAGTTTTCCCTTCTGTATCAAAACAAAATAATACAAAAAATGCTTTTAGAGTTTAAGC AATGGTTGAAATTTGTAGGTACTATCTGTCTTATTTTGTGTGTGTTTAGAGGTGTTCTAAAGACCCGTGGTAACAGGGCAAGTTTTCTAC GTTTTTAAGAGCCCTTAGAACGTGGGTATTTTTTTTCTTGAGAAAAGCTAATGCACCTACAGATGGCCCCCAACATTCTCTTCCTTTTGC TTCTAGTCAACCTTAATGGGCTGTTACAGAAACTAGTTCGTGTTTATATACTATTTCCTTTGATGTCCTATAAGTCGGAAAAGAAAGGGG CAAAGAGAACCTATTATTTGCCAGTTTTTAAGCAGAGCTCAATCTATGCCAGCTCTCTGGCATCTGGGGTTCCTGACTGATACCAGCAGT TGAAGGAAGAGAGTGCATGGCACCTGGTGTGTAACGACACAATCAGCACAACTGGAGAGAGGCATTAAAGAACCAGGGAAGGTAGTTTGA TTTTTCATTGAATTCTACAAGCTAATATTGTTCCACGTATGTAGTCTTAGACCAATAGCTGTAACTATCAGCTGCAATACCATGGTGACC AGCTGTTACAAAAGATTTTTTCCTGTTTTATCTGAAACATACTGGATTTATATATGTATAAGCGCCTCAATGGGGAATTAGAGCCAGATG TTATGATTTGTTTGCTCTTTTTCTTTTATAGTTTAGTTATAGCAAAAATATGGATAATTTCTAGTGAATGCATAAATTAGGTTGCGTTTC TTATTTTGCTTTAAATCTCTGGTAGTTTTTCCACCCCTGTGACACAATCCTAATAGACAGTGTCCTGTAAATGGACACAACACAATAAAG TCAAGTTATTATTGCTGTTACTCTGGATGATATGGAAAACACTGCCATATTTTAAATCAACTACTCCACGTGTTTTTCCATCCAATCACA CTGCTGTGATTCAGGGATCTTTCTTCTAAGACGGACACATTTGAACCTCAGGTTCATCACAAACCTGGTACCTGTTGCTTCCCAGAGGAT GGAGAAGTGTAGTTAATCACACCTCTTAGTTTAATCTGAAATCTTGACCCAGTTATTTAACAAATAAATACCTCATTGATTATATTTAAA AGTAATACACTTCCTGTAAACAAATGGGGACAATGCATCCAAAAAATCTTTTTAAACAGATTACACAAAAATTATTTCCAGAAAGGCTAC CATTTATCATCATTATATTTCAAGCCTCTTATACTTAATAAGCACTTTCTAAAAAGTCTTGAGATCCCACCATTCTGAGGAATTCAATAT GATCACTTTTTCCTTCTTTGCCTGGGAGAGGTTAAGAGGAGGTTTCGAAGGTATAGATGCTATTGTTCTGATGGCCCGGCTGAATAAAAT GGAAATTCTAGTTTGTTAGAATTATGCATTCTTTTTCAAGATTCTCAGTGTGCCTAACTTATTGGAGCACATCAGTTTCTTGGGTAATGG AAAACATTACCTAGAGTTGCCAGTGGCACATTACACCAGTACAGAGCACATTCCAAAGGAGACATTGGACCAGTTAATTCCCATACAAGT CAAGGTAACAGAACAAAAGGGAATCCTGATGCCCTTTTACCATTGCTGGTTGAGCTCAGGCACTGTCATGGACACCCTTAATTTTAAAAG GTTTTAATCATTCTTCTATAAAATACATTTAAAATGGAAAAATACTTAATATCACTAAATATCAGAACAATGTAACATTTACAAATGACA TATTGAAAGCAAAGGCTGTTTTATTTAGCCAAGATGATTACCATTAGGAGTTACTTTATGTATTGTTGAAAGCAAATTTTAAACATGATG TTTTAGAAGTGTTTCTGATTTTTAAACCTGGTTTACAGGTATTACTTCTGCACTTACCAAATAATGCCAGATGGAAATTTATTATTTCTT GCAATTCCCATGATAGCTCTGTTCTTTATGCATTGTCTCAACACTTTCCCTTTTTTCCCAAAATGAGTAGAGAATTAAAGCCACCCAAAA CAGCTTCTGCTACTAAAATGTTCTCATCCTTTCTCCTCCCTCTCCTTTTCCTGCCACAAAAGGTGAAAAATGAGATCCAATCCTCTCACC AAAATTTCAAACCTAGGACACTGGAATGACTGCAGGGATCAGTGGTTCTCCCATATCACCATCAATTAAGACATATAGGACACTGTCTTC CTTCAAGAGGGTTACAATGTGGCCATCAGACAGGAAACCAAACGGTGGATAAAGTATTAAGTAACTAAGTGCCAAATAAATGCTGGAAAT CTTGACCTCTCCTTGGGATTATGGGTGTAACAAAAATCCCTACATCTGTTTATGAAGGCCATATTCAGTACATTTTAAATGGTAAATAAT CTGTTTATGTGAAGAAAAAGAATTAAGTCTTTCTTCCAACTCTCTCCTTGGATAGCCTAGCACAGTGCAGCCTCCATAACCATGACATTC CCGCCCAAGCTCTCAGTGCCTAATCCTGCTTTGTCATTCACATCTCACAAAATCTTGACATCTTACATTCCAATACATTATCAAGCAAGC ACAAGTATGCTGGTAGTAGCCTCTTTAAATAATATGTATAGACAACAACAACGACAAAAAATAGACTGTTTTAAAGTTTCAGGGAAAGTT GGTGGCTGATTTAAAGTTGTGCAGGAAACATCTTCTGTGTATGAAGCAAATGTCGATGTTTTGAAAAAAGCTAGGAGATGACTTTGAATG AATGCAAGGTTAGTGAGATCCTAAGCTCTCAAAATAGCATATTCCCTAGAGCTCAAGAAAGCTGGTCCAGGAGGTTGAAAAAGCTATTTT GTTGTTAAATTATTTTCTGGCCCTTCTTAATATTTAAAAATGTATTTCCCCTTGTGGCTTTCAACCACCTGCTCAAAAAAAGAGACTTGT TACATGAAAGTTTTCATTAAAGAGCTGAAAACAAGAATTTAGAGAGCCATTCCTAGAAAATGTCCTACTGCCCTGCATTTGACAAACAAG CATCCTTTACTAACAAGAGCAGGAATTCAGAGGCACAAGAAAAAGCATTGGCATGAGCCAAAGAGTCTGTCTTAATGTTACTTTTGAAAA TCTGCTGAGCGGCCACCATATGCAGGCTGAGAGCTGGGCACAGGCGAAGCCATTGGAAGCACTTCAGGAACAAGCACACAGCTGTGGGAC TTGAACATGCAAGTGTTCAGGTTGTGTCAAGAAGCTTTTCTTTCCTTCTATGATGGAATCTGTTCTTTTCTATCCTACTTTTTTCTCTCT TCCTCTCCTCACCACATTATACCCTGCTCTTACGCAGTAAACGTTTTAATGGCCCGTTTATGTCTCATGCCTCCAAACAACACTGAATTT GAAACCCCCCATTTTTTCTTTTCACCACCCTGTTGAGCAATTTTCCCAAAAAAAGGGCAGCAATTATTAAATTGAATTCAAGTAAGCCAG CCAAAGATAGGTCCTAAATTGCTAGTCCCAGTAGAACCACCTGATCCTAAACCAGTGCGAAACAAACAGTAACAATGTCCCCAGCTGACT TCAGCTAAGAACCAATGGCTCCTACCCCCGCCCCGCTTTTTTTTGTTGTTTTTTGTTTTGTTTTGAGACGGAGTCTTGCTCTGTCCCCCA GGCTGGAGTGCACTGGCGCAATCTCGGGCTCACTGCAACCTCCTCCTCCTCCCACATTGAGGCGATTCTCCTGCCTCAGCCTCCCAAGTA GCTGGGATTACAGGCACCCGCCATCACACCCAGCTAATTTTTTTTTTTTTTTGTATTATTAGTAGAAGCCAGGTTTCACCATGTTGGCCA GGGTGGTCTCGAACTCCTGACCTCAAGTGATCCGTCCACCTCGGCCTTGCAAATTGCTGGGATTACAGGTGTGAGCCACCGTGCCGAGCC AGCCCCATTTTTTAAATGATGTTTTGGTTAAGAGTGGACCATGAGAATTAGCTGACAGCATCCCCTTTCTCTCTCCCTGCCTTGGTGGGA CCCTCCCTGTGTGACCTTGGTCAAGTCCTCGAACTTTTGTCCCGTATTTAAGATGGAGCTGTTTTACCTACTTCATAAGACAGTTGCGAG GTGCCATTGATTCTTGACTGCAAAATACCTTGAAACCCTTATATAAAGACTGAAGTCAACGGAGCCTAGTGAAAGACTTACTTTGTGGCT TGTGGTTGAAAGTCACATCAAAAGACAAATGTGGCCACGTTCAGGAATTGGAGACTTACTGGCATGGCTCTACAGCTGCTCAGTTATTAA TCATGCAGACTAACCTGTCAACACTGGGAGATGCAACATAGCAAAAGGACAGAGAAATTAGAATTTTTTGTGCAGAAAGCCCTAAATTCC CACCTGAATGTAACTTACAGCTCCCTTACCTACTCTCACACATGCCCTCAAACATGCTAGATTGGCTTATACATAGGCCAACACAAAATA CAAACGTGACGTGTTCATGTAGCCTAGTGGCTATATGCCTATTCTCCATGTACCCTGCATGGTAGTGCTGCAAACTTTAAAGTACATTTC TTTCACAGCAGTATTTTTTTTCATAAGTGGCATATAAATGTCATTCAATGAAATGGGGAAATCACGTTGAGAAGTTGGTCTGTCATCTCC CATTGAGCAAAGACTGGCAGGAGATAATAAAAATAAATATGGGCACACATGTATTAATATACAGCACGCATTTACAAGTTTATTTTCCAG ATAAAATTGTGCTATAAGAACAGCTCTACCAAGACAGTCTGCACCATTTCCAAGTCTCAGTTAATTTACAGCAACTGCTGCTTTCGGAGA TGGCTGTGAAAATATGGAAGTTCCTCTCAAGTAGGCCAAGAAACAGTTCTAGATTTTACTAAGTTTTATTTTGTCAGGTTTTTTAAATTT TTTCAGTGAGCGTGGTGACTGCAGAGGTTAGTGCTGTGAAAAGCTGGGCTAAATATTCTTTCTGTAAAGTCAAACAGGATTCCATCCCCT GTGAAATAACACAAAATTTCACTCTCTAAAAGCAACAGCATGTAAACTAGAATGAAAGAAGGAAATTATGTACGTATGCCTAATATTCTT |
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FusionGenePPI for GALNT11_CNTNAP2 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| GALNT11 | KLK11, HLA-DPA1, SPACA1, NRG1, SDF4, DHRS9, SUCLG2, VSIG4, FNDC4, TOR1AIP2, P2RX2, TMPRSS11B, PDCD1, ARMC6 | CNTNAP2 | CNTN2, EPB41L3, CASK, CTR9, ZMIZ1, MACF1, IQCB1, MEOX2 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for GALNT11_CNTNAP2 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for GALNT11_CNTNAP2 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Tgene | CNTNAP2 | C0004352 | Autistic Disorder | 4 | CTD_human |
| Tgene | CNTNAP2 | C1510586 | Autism Spectrum Disorders | 4 | CTD_human |
| Tgene | CNTNAP2 | C0023014 | Language Development Disorders | 3 | CTD_human |
| Tgene | CNTNAP2 | C0014544 | Epilepsy | 2 | CTD_human;HPO |
| Tgene | CNTNAP2 | C0001973 | Alcoholic Intoxication, Chronic | 1 | PSYGENET |
| Tgene | CNTNAP2 | C0005586 | Bipolar Disorder | 1 | PSYGENET |
| Tgene | CNTNAP2 | C0036341 | Schizophrenia | 1 | CTD_human |
| Tgene | CNTNAP2 | C0038506 | Stuttering | 1 | CTD_human |
| Tgene | CNTNAP2 | C0041696 | Unipolar Depression | 1 | PSYGENET |
| Tgene | CNTNAP2 | C0149925 | Small cell carcinoma of lung | 1 | CTD_human |
| Tgene | CNTNAP2 | C0424295 | Hyperactive behavior | 1 | CTD_human;HPO |
| Tgene | CNTNAP2 | C1269683 | Major Depressive Disorder | 1 | PSYGENET |
| Tgene | CNTNAP2 | C1970431 | PITT-HOPKINS SYNDROME | 1 | CTD_human |
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