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Fusion gene ID: 14279 |
FusionGeneSummary for GALNS_CCNG2 |
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Fusion gene information | Fusion gene name: GALNS_CCNG2 | Fusion gene ID: 14279 | Hgene | Tgene | Gene symbol | GALNS | CCNG2 | Gene ID | 2588 | 901 |
Gene name | galactosamine (N-acetyl)-6-sulfatase | cyclin G2 | |
Synonyms | GALNAC6S|GAS|GalN6S|MPS4A | - | |
Cytomap | 16q24.3 | 4q21.1 | |
Type of gene | protein-coding | protein-coding | |
Description | N-acetylgalactosamine-6-sulfataseN-acetylgalactosamine-6-sulfate sulfatasechondroitinasechondroitinsulfatasegalNAc6S sulfatasegalactosamine (N-acetyl)-6-sulfate sulfatasegalactose-6-sulfate sulfatase | cyclin-G2 | |
Modification date | 20180522 | 20180523 | |
UniProtAcc | P34059 | Q16589 | |
Ensembl transtripts involved in fusion gene | ENST00000268695, ENST00000542788, ENST00000565364, ENST00000568311, ENST00000569433, | ENST00000497512, ENST00000316355, ENST00000354403, ENST00000502280, ENST00000395640, ENST00000509972, | |
Fusion gene scores | * DoF score | 2 X 1 X 2=4 | 3 X 2 X 2=12 |
# samples | 2 | 3 | |
** MAII score | log2(2/4*10)=2.32192809488736 | log2(3/12*10)=1.32192809488736 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
Context | PubMed: GALNS [Title/Abstract] AND CCNG2 [Title/Abstract] AND fusion [Title/Abstract] | ||
Functional or gene categories assigned by FusionGDB annotation |
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
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Partner | Gene | GO ID | GO term | PubMed ID |
![]() (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
ChiTaRS3.1 | DN998848 | GALNS | chr16 | 88923166 | - | CCNG2 | chr4 | 78079686 | + |
* LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
![]() * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
5CDS-3UTR | ENST00000268695 | ENST00000497512 | GALNS | chr16 | 88923166 | - | CCNG2 | chr4 | 78079686 | + |
5CDS-3UTR | ENST00000268695 | ENST00000316355 | GALNS | chr16 | 88923166 | - | CCNG2 | chr4 | 78079686 | + |
5CDS-3UTR | ENST00000268695 | ENST00000354403 | GALNS | chr16 | 88923166 | - | CCNG2 | chr4 | 78079686 | + |
5CDS-3UTR | ENST00000268695 | ENST00000502280 | GALNS | chr16 | 88923166 | - | CCNG2 | chr4 | 78079686 | + |
5CDS-3UTR | ENST00000268695 | ENST00000395640 | GALNS | chr16 | 88923166 | - | CCNG2 | chr4 | 78079686 | + |
5CDS-3UTR | ENST00000268695 | ENST00000509972 | GALNS | chr16 | 88923166 | - | CCNG2 | chr4 | 78079686 | + |
intron-3UTR | ENST00000542788 | ENST00000497512 | GALNS | chr16 | 88923166 | - | CCNG2 | chr4 | 78079686 | + |
intron-3UTR | ENST00000542788 | ENST00000316355 | GALNS | chr16 | 88923166 | - | CCNG2 | chr4 | 78079686 | + |
intron-3UTR | ENST00000542788 | ENST00000354403 | GALNS | chr16 | 88923166 | - | CCNG2 | chr4 | 78079686 | + |
intron-3UTR | ENST00000542788 | ENST00000502280 | GALNS | chr16 | 88923166 | - | CCNG2 | chr4 | 78079686 | + |
intron-3UTR | ENST00000542788 | ENST00000395640 | GALNS | chr16 | 88923166 | - | CCNG2 | chr4 | 78079686 | + |
intron-3UTR | ENST00000542788 | ENST00000509972 | GALNS | chr16 | 88923166 | - | CCNG2 | chr4 | 78079686 | + |
5UTR-3UTR | ENST00000565364 | ENST00000497512 | GALNS | chr16 | 88923166 | - | CCNG2 | chr4 | 78079686 | + |
5UTR-3UTR | ENST00000565364 | ENST00000316355 | GALNS | chr16 | 88923166 | - | CCNG2 | chr4 | 78079686 | + |
5UTR-3UTR | ENST00000565364 | ENST00000354403 | GALNS | chr16 | 88923166 | - | CCNG2 | chr4 | 78079686 | + |
5UTR-3UTR | ENST00000565364 | ENST00000502280 | GALNS | chr16 | 88923166 | - | CCNG2 | chr4 | 78079686 | + |
5UTR-3UTR | ENST00000565364 | ENST00000395640 | GALNS | chr16 | 88923166 | - | CCNG2 | chr4 | 78079686 | + |
5UTR-3UTR | ENST00000565364 | ENST00000509972 | GALNS | chr16 | 88923166 | - | CCNG2 | chr4 | 78079686 | + |
5CDS-3UTR | ENST00000568311 | ENST00000497512 | GALNS | chr16 | 88923166 | - | CCNG2 | chr4 | 78079686 | + |
5CDS-3UTR | ENST00000568311 | ENST00000316355 | GALNS | chr16 | 88923166 | - | CCNG2 | chr4 | 78079686 | + |
5CDS-3UTR | ENST00000568311 | ENST00000354403 | GALNS | chr16 | 88923166 | - | CCNG2 | chr4 | 78079686 | + |
5CDS-3UTR | ENST00000568311 | ENST00000502280 | GALNS | chr16 | 88923166 | - | CCNG2 | chr4 | 78079686 | + |
5CDS-3UTR | ENST00000568311 | ENST00000395640 | GALNS | chr16 | 88923166 | - | CCNG2 | chr4 | 78079686 | + |
5CDS-3UTR | ENST00000568311 | ENST00000509972 | GALNS | chr16 | 88923166 | - | CCNG2 | chr4 | 78079686 | + |
5CDS-3UTR | ENST00000569433 | ENST00000497512 | GALNS | chr16 | 88923166 | - | CCNG2 | chr4 | 78079686 | + |
5CDS-3UTR | ENST00000569433 | ENST00000316355 | GALNS | chr16 | 88923166 | - | CCNG2 | chr4 | 78079686 | + |
5CDS-3UTR | ENST00000569433 | ENST00000354403 | GALNS | chr16 | 88923166 | - | CCNG2 | chr4 | 78079686 | + |
5CDS-3UTR | ENST00000569433 | ENST00000502280 | GALNS | chr16 | 88923166 | - | CCNG2 | chr4 | 78079686 | + |
5CDS-3UTR | ENST00000569433 | ENST00000395640 | GALNS | chr16 | 88923166 | - | CCNG2 | chr4 | 78079686 | + |
5CDS-3UTR | ENST00000569433 | ENST00000509972 | GALNS | chr16 | 88923166 | - | CCNG2 | chr4 | 78079686 | + |
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FusionProtFeatures for GALNS_CCNG2 |
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Hgene | Tgene |
GALNS | CCNG2 |
May play a role in growth regulation and in negativeregulation of cell cycle progression. |
![]() * Minus value of BPloci means that the break pointn is located before the CDS. |
- In-frame and retained protein feature among the 13 regional features. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
- In-frame and not-retained protein feature among the 13 regional features. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
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FusionGeneSequence for GALNS_CCNG2 |
![]() (nt: nucleotides, aa: amino acids) |
* Fusion amino acid sequences. |
* Fusion transcript sequences (only coding sequence (CDS) region). |
* Fusion transcript sequences (Full-length transcript). |
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FusionGenePPI for GALNS_CCNG2 |
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Hgene | Hgene's interactors | Tgene | Tgene's interactors |
GALNS | NEU1, TAZ, IDS, PLAUR, DNASE2B, PTPRK, DPEP2, ISLR, NAAA, ARSA, ATXN2L, PRG3, LYZL1, P2RX5, LYPD4, LYZL2, WNT16, OLFM2, INSL5, SLAMF1, ALPPL2, TPSB2, ERLIN2, DEFA1, SIAE, TDGF1, PSG8, PRG2, SPACA4, MTNR1A | CCNG2 | PPP2R5B, PPP2R5C, PPP2CA, SKP1, SKP2, NRIP2, FAM208B, EFHC2, PPP2R5D, NME2, PPP2R5E |
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Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
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Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for GALNS_CCNG2 |
![]() (DrugBank Version 5.1.0 2018-04-02) |
Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for GALNS_CCNG2 |
![]() (DisGeNet 4.0) |
Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
Hgene | GALNS | C0086651 | Mucopolysaccharidosis, MPS-IV-A | 8 | ORPHANET;UNIPROT |
Hgene | GALNS | C0021368 | Inflammation | 1 | CTD_human |