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Fusion gene ID: 14233 |
FusionGeneSummary for GABPB2_OR10J1 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: GABPB2_OR10J1 | Fusion gene ID: 14233 | Hgene | Tgene | Gene symbol | GABPB2 | OR10J1 | Gene ID | 126626 | 26476 |
| Gene name | GA binding protein transcription factor subunit beta 2 | olfactory receptor family 10 subfamily J member 1 | |
| Synonyms | GABPB-2 | HGMP07J|HSHGMP07J | |
| Cytomap | 1q21.3 | 1q23.2 | |
| Type of gene | protein-coding | protein-coding | |
| Description | GA-binding protein subunit beta-2GA binding protein transcription factor beta subunit 2GABP subunit beta-2 | olfactory receptor 10J1olfactory receptor OR1-26olfactory receptor-like protein HGMP07J | |
| Modification date | 20180519 | 20180525 | |
| UniProtAcc | Q8TAK5 | P30954 | |
| Ensembl transtripts involved in fusion gene | ENST00000368917, ENST00000368918, ENST00000368916, ENST00000467551, | ENST00000423932, | |
| Fusion gene scores | * DoF score | 3 X 2 X 3=18 | 2 X 1 X 2=4 |
| # samples | 3 | 2 | |
| ** MAII score | log2(3/18*10)=0.736965594166206 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | log2(2/4*10)=2.32192809488736 | |
| Context | PubMed: GABPB2 [Title/Abstract] AND OR10J1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | GABPB2 | GO:0045944 | positive regulation of transcription by RNA polymerase II | 9857059 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | BRCA | TCGA-AR-A24Z-01A | GABPB2 | chr1 | 151070478 | + | OR10J1 | chr1 | 159409566 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000368917 | ENST00000423932 | GABPB2 | chr1 | 151070478 | + | OR10J1 | chr1 | 159409566 | + |
| In-frame | ENST00000368918 | ENST00000423932 | GABPB2 | chr1 | 151070478 | + | OR10J1 | chr1 | 159409566 | + |
| In-frame | ENST00000368916 | ENST00000423932 | GABPB2 | chr1 | 151070478 | + | OR10J1 | chr1 | 159409566 | + |
| 3UTR-3CDS | ENST00000467551 | ENST00000423932 | GABPB2 | chr1 | 151070478 | + | OR10J1 | chr1 | 159409566 | + |
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FusionProtFeatures for GABPB2_OR10J1 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| GABPB2 | OR10J1 |
| May function as transcription factor capable ofinteracting with purine rich repeats (GA repeats). {ECO:0000250}. | Odorant receptor. {ECO:0000305}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | GABPB2 | chr1:151070478 | chr1:159409566 | ENST00000368918 | + | 5 | 9 | 103_132 | 207 | 449 | Repeat | Note=ANK 4 |
| Hgene | GABPB2 | chr1:151070478 | chr1:159409566 | ENST00000368918 | + | 5 | 9 | 136_166 | 207 | 449 | Repeat | Note=ANK 5 |
| Hgene | GABPB2 | chr1:151070478 | chr1:159409566 | ENST00000368918 | + | 5 | 9 | 37_66 | 207 | 449 | Repeat | Note=ANK 2 |
| Hgene | GABPB2 | chr1:151070478 | chr1:159409566 | ENST00000368918 | + | 5 | 9 | 5_34 | 207 | 449 | Repeat | Note=ANK 1 |
| Hgene | GABPB2 | chr1:151070478 | chr1:159409566 | ENST00000368918 | + | 5 | 9 | 70_99 | 207 | 449 | Repeat | Note=ANK 3 |
| Tgene | >OR10J1 | chr1:151070478 | chr1:159409566 | ENST00000423932 | + | 0 | 1 | 132_150 | -13 | 321 | Topological domain | Cytoplasmic |
| Tgene | >OR10J1 | chr1:151070478 | chr1:159409566 | ENST00000423932 | + | 0 | 1 | 172_207 | -13 | 321 | Topological domain | Extracellular |
| Tgene | >OR10J1 | chr1:151070478 | chr1:159409566 | ENST00000423932 | + | 0 | 1 | 1_36 | -13 | 321 | Topological domain | Extracellular |
| Tgene | >OR10J1 | chr1:151070478 | chr1:159409566 | ENST00000423932 | + | 0 | 1 | 228_247 | -13 | 321 | Topological domain | Cytoplasmic |
| Tgene | >OR10J1 | chr1:151070478 | chr1:159409566 | ENST00000423932 | + | 0 | 1 | 269_281 | -13 | 321 | Topological domain | Extracellular |
| Tgene | >OR10J1 | chr1:151070478 | chr1:159409566 | ENST00000423932 | + | 0 | 1 | 303_320 | -13 | 321 | Topological domain | Cytoplasmic |
| Tgene | >OR10J1 | chr1:151070478 | chr1:159409566 | ENST00000423932 | + | 0 | 1 | 58_65 | -13 | 321 | Topological domain | Cytoplasmic |
| Tgene | >OR10J1 | chr1:151070478 | chr1:159409566 | ENST00000423932 | + | 0 | 1 | 87_110 | -13 | 321 | Topological domain | Extracellular |
| Tgene | >OR10J1 | chr1:151070478 | chr1:159409566 | ENST00000423932 | + | 0 | 1 | 111_131 | -13 | 321 | Transmembrane | Helical%3B Name%3D3 |
| Tgene | >OR10J1 | chr1:151070478 | chr1:159409566 | ENST00000423932 | + | 0 | 1 | 151_171 | -13 | 321 | Transmembrane | Helical%3B Name%3D4 |
| Tgene | >OR10J1 | chr1:151070478 | chr1:159409566 | ENST00000423932 | + | 0 | 1 | 208_227 | -13 | 321 | Transmembrane | Helical%3B Name%3D5 |
| Tgene | >OR10J1 | chr1:151070478 | chr1:159409566 | ENST00000423932 | + | 0 | 1 | 248_268 | -13 | 321 | Transmembrane | Helical%3B Name%3D6 |
| Tgene | >OR10J1 | chr1:151070478 | chr1:159409566 | ENST00000423932 | + | 0 | 1 | 282_302 | -13 | 321 | Transmembrane | Helical%3B Name%3D7 |
| Tgene | >OR10J1 | chr1:151070478 | chr1:159409566 | ENST00000423932 | + | 0 | 1 | 37_57 | -13 | 321 | Transmembrane | Helical%3B Name%3D1 |
| Tgene | >OR10J1 | chr1:151070478 | chr1:159409566 | ENST00000423932 | + | 0 | 1 | 66_86 | -13 | 321 | Transmembrane | Helical%3B Name%3D2 |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >GABPB2 | chr1:151070478 | chr1:159409566 | ENST00000368918 | + | 5 | 9 | 345_395 | 207 | 449 | Coiled coil | Ontology_term=ECO:0000255 |
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FusionGeneSequence for GABPB2_OR10J1 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_GABPB2_ENST00000368917_chr1_151070478_+_OR10J1_ENST00000423932_chr1_159409566_+_237aa MSLVDLGKRLLEAARKGQDDEVRTLMANGAPFTTDWLGTSPLHLAAQYGHYSTAEVLLRAGVSRDARTKVDRTPLHMAAADGHAHIVELL VRNGADVNAKDMLKMTALHWATERHHRDVVELLIKYGADVHAFSKFDKSAFDIALEKNNAEILVILQEAMQNQVNVNPERANPVTDPVSM >In-frame_GABPB2_ENST00000368918_chr1_151070478_+_OR10J1_ENST00000423932_chr1_159409566_+_237aa MSLVDLGKRLLEAARKGQDDEVRTLMANGAPFTTDWLGTSPLHLAAQYGHYSTAEVLLRAGVSRDARTKVDRTPLHMAAADGHAHIVELL VRNGADVNAKDMLKMTALHWATERHHRDVVELLIKYGADVHAFSKFDKSAFDIALEKNNAEILVILQEAMQNQVNVNPERANPVTDPVSM >In-frame_GABPB2_ENST00000368916_chr1_151070478_+_OR10J1_ENST00000423932_chr1_159409566_+_237aa MSLVDLGKRLLEAARKGQDDEVRTLMANGAPFTTDWLGTSPLHLAAQYGHYSTAEVLLRAGVSRDARTKVDRTPLHMAAADGHAHIVELL VRNGADVNAKDMLKMTALHWATERHHRDVVELLIKYGADVHAFSKFDKSAFDIALEKNNAEILVILQEAMQNQVNVNPERANPVTDPVSM |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_GABPB2_ENST00000368917_chr1_151070478_+_OR10J1_ENST00000423932_chr1_159409566_+_711nt ATGTCTTTGGTGGACTTGGGAAAGAGGTTGCTAGAAGCAGCAAGAAAAGGCCAAGATGATGAAGTGAGAACGTTGATGGCAAATGGCGCC CCATTCACCACAGACTGGCTTGGAACATCACCCCTCCACCTTGCAGCTCAATATGGTCATTATTCCACAGCAGAAGTACTCCTTCGAGCA GGTGTTAGCAGGGATGCCCGGACTAAAGTAGACAGGACCCCCTTGCACATGGCTGCAGCCGATGGACATGCGCACATCGTGGAACTGCTT GTTCGGAATGGTGCAGATGTGAATGCCAAGGACATGCTGAAGATGACAGCTTTGCATTGGGCCACAGAGCGCCACCATCGAGATGTCGTA GAGTTACTTATCAAATATGGAGCTGATGTCCATGCTTTCAGCAAATTTGATAAATCAGCCTTTGACATAGCTCTGGAGAAAAACAATGCT GAGATTTTGGTCATCCTCCAGGAAGCAATGCAGAATCAGGTGAATGTTAATCCAGAGAGAGCCAACCCTGTGACTGACCCTGTGAGTATG GCTGCTCCATTCATCTTCACGTCGGGTGAGGTTGTTAACCTCGCAAGCCTTATTTCTTCAACCAACACCAAAACAACCTCAGCCATGTAG >In-frame_GABPB2_ENST00000368918_chr1_151070478_+_OR10J1_ENST00000423932_chr1_159409566_+_711nt ATGTCTTTGGTGGACTTGGGAAAGAGGTTGCTAGAAGCAGCAAGAAAAGGCCAAGATGATGAAGTGAGAACGTTGATGGCAAATGGCGCC CCATTCACCACAGACTGGCTTGGAACATCACCCCTCCACCTTGCAGCTCAATATGGTCATTATTCCACAGCAGAAGTACTCCTTCGAGCA GGTGTTAGCAGGGATGCCCGGACTAAAGTAGACAGGACCCCCTTGCACATGGCTGCAGCCGATGGACATGCGCACATCGTGGAACTGCTT GTTCGGAATGGTGCAGATGTGAATGCCAAGGACATGCTGAAGATGACAGCTTTGCATTGGGCCACAGAGCGCCACCATCGAGATGTCGTA GAGTTACTTATCAAATATGGAGCTGATGTCCATGCTTTCAGCAAATTTGATAAATCAGCCTTTGACATAGCTCTGGAGAAAAACAATGCT GAGATTTTGGTCATCCTCCAGGAAGCAATGCAGAATCAGGTGAATGTTAATCCAGAGAGAGCCAACCCTGTGACTGACCCTGTGAGTATG GCTGCTCCATTCATCTTCACGTCGGGTGAGGTTGTTAACCTCGCAAGCCTTATTTCTTCAACCAACACCAAAACAACCTCAGCCATGTAG >In-frame_GABPB2_ENST00000368916_chr1_151070478_+_OR10J1_ENST00000423932_chr1_159409566_+_711nt ATGTCTTTGGTGGACTTGGGAAAGAGGTTGCTAGAAGCAGCAAGAAAAGGCCAAGATGATGAAGTGAGAACGTTGATGGCAAATGGCGCC CCATTCACCACAGACTGGCTTGGAACATCACCCCTCCACCTTGCAGCTCAATATGGTCATTATTCCACAGCAGAAGTACTCCTTCGAGCA GGTGTTAGCAGGGATGCCCGGACTAAAGTAGACAGGACCCCCTTGCACATGGCTGCAGCCGATGGACATGCGCACATCGTGGAACTGCTT GTTCGGAATGGTGCAGATGTGAATGCCAAGGACATGCTGAAGATGACAGCTTTGCATTGGGCCACAGAGCGCCACCATCGAGATGTCGTA GAGTTACTTATCAAATATGGAGCTGATGTCCATGCTTTCAGCAAATTTGATAAATCAGCCTTTGACATAGCTCTGGAGAAAAACAATGCT GAGATTTTGGTCATCCTCCAGGAAGCAATGCAGAATCAGGTGAATGTTAATCCAGAGAGAGCCAACCCTGTGACTGACCCTGTGAGTATG GCTGCTCCATTCATCTTCACGTCGGGTGAGGTTGTTAACCTCGCAAGCCTTATTTCTTCAACCAACACCAAAACAACCTCAGCCATGTAG |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_GABPB2_ENST00000368917_chr1_151070478_+_OR10J1_ENST00000423932_chr1_159409566_+_1987nt GCACTTTTCCACCTCAGAAGTGCCTCAGCAGAAAGGCGATGAACCTCGGGGGTGCATCATCTTTCTGTTAGAATGGGAGCATGAGTTTTC TGATCATTTTCCCTTCACAGATTCCTCCGCCAGAAATCTTACTCGCGGCGCCTTCATTTCCGGGTCCGCCATTTTGTTGCCTCTGTTTCT CCACGAGGGGGGGTTAAAGGCCCCCAAAACATGCACACATGAAAAGGGCAAAAAGTAACCGTCCTTGACAGGGAGTCTTAACTAGAGAAG GAAACGGGACTAAACTGGCGGGCTCCGTGGAAGCGTGGCCGGCAGCGTCCCGGACGAGGAGATGTCTTTGGTGGACTTGGGAAAGAGGTT GCTAGAAGCAGCAAGAAAAGGCCAAGATGATGAAGTGAGAACGTTGATGGCAAATGGCGCCCCATTCACCACAGACTGGCTTGGAACATC ACCCCTCCACCTTGCAGCTCAATATGGTCATTATTCCACAGCAGAAGTACTCCTTCGAGCAGGTGTTAGCAGGGATGCCCGGACTAAAGT AGACAGGACCCCCTTGCACATGGCTGCAGCCGATGGACATGCGCACATCGTGGAACTGCTTGTTCGGAATGGTGCAGATGTGAATGCCAA GGACATGCTGAAGATGACAGCTTTGCATTGGGCCACAGAGCGCCACCATCGAGATGTCGTAGAGTTACTTATCAAATATGGAGCTGATGT CCATGCTTTCAGCAAATTTGATAAATCAGCCTTTGACATAGCTCTGGAGAAAAACAATGCTGAGATTTTGGTCATCCTCCAGGAAGCAAT GCAGAATCAGGTGAATGTTAATCCAGAGAGAGCCAACCCTGTGACTGACCCTGTGAGTATGGCTGCTCCATTCATCTTCACGTCGGGTGA GGTTGTTAACCTCGCAAGCCTTATTTCTTCAACCAACACCAAAACAACCTCAGTTTGGGAACCAATCCATGAAAAGAGAGAACTTTACTC TCATCACTGACTTTGTTTTCCAAGGTTTCTCTAGCTTCCATGAGCAGCAGATCACCCTTTTTGGCGTGTTCCTTGCACTATACATCTTAA CCTTAGCAGGCAATATCATCATTGTGACCATCATCCGAATGGATCTTCATCTTCACACACCCATGTACTTCTTCCTGAGCATGCTGTCCA CTTCAGAGACTGTATATACATTGGTCATTCTCCCAAGAATGCTCTCCAGCCTCGTAGGTATGAGCCAGCCCATATCATTGGCAGGGTGTG CCACACAGATGTTCTTTTTTGTAACCTTTGGCATCACTAACTGCTTCCTGCTCACAGCAATGGGATATGACCGCTATGTGGCCATCTGCA ACCCCCTGAGATACATGGTTATTATGAACAAGAGGCTGCGTATCCAACTTGTCCTGGGGGCCTGCAGCATTGGGCTGATTGTAGCAATAA CGCAAGTGACATCTGTATTCAGGTTACCCTTCTGTGCTAGAAAGGTGCCCCACTTCTTCTGTGACATCCGCCCTGTGATGAAGCTCTCCT GCATTGACACCACTGTCAATGAAATCCTGACTTTGATTATCAGTGTGCTGGTGCTTGTTGTACCTATGGGTCTGGTTTTCATTTCTTATG TTCTCATTATCTCTACAATCCTCAAGATTGCTTCAGTTGAGGGCCGGAAGAAGGCTTTTGCCACCTGTGCATCCCACCTCACTGTGGTCA TTGTCCACTACAGCTGTGCCTCCATTGCCTACCTCAAGCCCAAGTCAGAGAACACCAGAGAACATGACCAGCTGATCTCGGTGACCTACA CTGTCATCACTCCCCTACTGAACCCTGTGGTATACACCCTGAGAAATAAAGAGGTCAAAGATGCTCTGTGCAGGGCTGTTGGTGGGAAGT TTTCCTGACCATGTAGGAAGAGTTCTCCTGAGGCTGTCAACATCCACACTAGGCAGGAATATGAGGTGTAAACTCACAAACACTTGGCTC >In-frame_GABPB2_ENST00000368918_chr1_151070478_+_OR10J1_ENST00000423932_chr1_159409566_+_1987nt GCACTTTTCCACCTCAGAAGTGCCTCAGCAGAAAGGCGATGAACCTCGGGGGTGCATCATCTTTCTGTTAGAATGGGAGCATGAGTTTTC TGATCATTTTCCCTTCACAGATTCCTCCGCCAGAAATCTTACTCGCGGCGCCTTCATTTCCGGGTCCGCCATTTTGTTGCCTCTGTTTCT CCACGAGGGGGGGTTAAAGGCCCCCAAAACATGCACACATGAAAAGGGCAAAAAGTAACCGTCCTTGACAGGGAGTCTTAACTAGAGAAG GAAACGGGACTAAACTGGCGGGCTCCGTGGAAGCGTGGCCGGCAGCGTCCCGGACGAGGAGATGTCTTTGGTGGACTTGGGAAAGAGGTT GCTAGAAGCAGCAAGAAAAGGCCAAGATGATGAAGTGAGAACGTTGATGGCAAATGGCGCCCCATTCACCACAGACTGGCTTGGAACATC ACCCCTCCACCTTGCAGCTCAATATGGTCATTATTCCACAGCAGAAGTACTCCTTCGAGCAGGTGTTAGCAGGGATGCCCGGACTAAAGT AGACAGGACCCCCTTGCACATGGCTGCAGCCGATGGACATGCGCACATCGTGGAACTGCTTGTTCGGAATGGTGCAGATGTGAATGCCAA GGACATGCTGAAGATGACAGCTTTGCATTGGGCCACAGAGCGCCACCATCGAGATGTCGTAGAGTTACTTATCAAATATGGAGCTGATGT CCATGCTTTCAGCAAATTTGATAAATCAGCCTTTGACATAGCTCTGGAGAAAAACAATGCTGAGATTTTGGTCATCCTCCAGGAAGCAAT GCAGAATCAGGTGAATGTTAATCCAGAGAGAGCCAACCCTGTGACTGACCCTGTGAGTATGGCTGCTCCATTCATCTTCACGTCGGGTGA GGTTGTTAACCTCGCAAGCCTTATTTCTTCAACCAACACCAAAACAACCTCAGTTTGGGAACCAATCCATGAAAAGAGAGAACTTTACTC TCATCACTGACTTTGTTTTCCAAGGTTTCTCTAGCTTCCATGAGCAGCAGATCACCCTTTTTGGCGTGTTCCTTGCACTATACATCTTAA CCTTAGCAGGCAATATCATCATTGTGACCATCATCCGAATGGATCTTCATCTTCACACACCCATGTACTTCTTCCTGAGCATGCTGTCCA CTTCAGAGACTGTATATACATTGGTCATTCTCCCAAGAATGCTCTCCAGCCTCGTAGGTATGAGCCAGCCCATATCATTGGCAGGGTGTG CCACACAGATGTTCTTTTTTGTAACCTTTGGCATCACTAACTGCTTCCTGCTCACAGCAATGGGATATGACCGCTATGTGGCCATCTGCA ACCCCCTGAGATACATGGTTATTATGAACAAGAGGCTGCGTATCCAACTTGTCCTGGGGGCCTGCAGCATTGGGCTGATTGTAGCAATAA CGCAAGTGACATCTGTATTCAGGTTACCCTTCTGTGCTAGAAAGGTGCCCCACTTCTTCTGTGACATCCGCCCTGTGATGAAGCTCTCCT GCATTGACACCACTGTCAATGAAATCCTGACTTTGATTATCAGTGTGCTGGTGCTTGTTGTACCTATGGGTCTGGTTTTCATTTCTTATG TTCTCATTATCTCTACAATCCTCAAGATTGCTTCAGTTGAGGGCCGGAAGAAGGCTTTTGCCACCTGTGCATCCCACCTCACTGTGGTCA TTGTCCACTACAGCTGTGCCTCCATTGCCTACCTCAAGCCCAAGTCAGAGAACACCAGAGAACATGACCAGCTGATCTCGGTGACCTACA CTGTCATCACTCCCCTACTGAACCCTGTGGTATACACCCTGAGAAATAAAGAGGTCAAAGATGCTCTGTGCAGGGCTGTTGGTGGGAAGT TTTCCTGACCATGTAGGAAGAGTTCTCCTGAGGCTGTCAACATCCACACTAGGCAGGAATATGAGGTGTAAACTCACAAACACTTGGCTC >In-frame_GABPB2_ENST00000368916_chr1_151070478_+_OR10J1_ENST00000423932_chr1_159409566_+_1688nt CTACCTGAAAACTTTTGTTCCTATGCATAAAGATGTCTTTGGTGGACTTGGGAAAGAGGTTGCTAGAAGCAGCAAGAAAAGGCCAAGATG ATGAAGTGAGAACGTTGATGGCAAATGGCGCCCCATTCACCACAGACTGGCTTGGAACATCACCCCTCCACCTTGCAGCTCAATATGGTC ATTATTCCACAGCAGAAGTACTCCTTCGAGCAGGTGTTAGCAGGGATGCCCGGACTAAAGTAGACAGGACCCCCTTGCACATGGCTGCAG CCGATGGACATGCGCACATCGTGGAACTGCTTGTTCGGAATGGTGCAGATGTGAATGCCAAGGACATGCTGAAGATGACAGCTTTGCATT GGGCCACAGAGCGCCACCATCGAGATGTCGTAGAGTTACTTATCAAATATGGAGCTGATGTCCATGCTTTCAGCAAATTTGATAAATCAG CCTTTGACATAGCTCTGGAGAAAAACAATGCTGAGATTTTGGTCATCCTCCAGGAAGCAATGCAGAATCAGGTGAATGTTAATCCAGAGA GAGCCAACCCTGTGACTGACCCTGTGAGTATGGCTGCTCCATTCATCTTCACGTCGGGTGAGGTTGTTAACCTCGCAAGCCTTATTTCTT CAACCAACACCAAAACAACCTCAGTTTGGGAACCAATCCATGAAAAGAGAGAACTTTACTCTCATCACTGACTTTGTTTTCCAAGGTTTC TCTAGCTTCCATGAGCAGCAGATCACCCTTTTTGGCGTGTTCCTTGCACTATACATCTTAACCTTAGCAGGCAATATCATCATTGTGACC ATCATCCGAATGGATCTTCATCTTCACACACCCATGTACTTCTTCCTGAGCATGCTGTCCACTTCAGAGACTGTATATACATTGGTCATT CTCCCAAGAATGCTCTCCAGCCTCGTAGGTATGAGCCAGCCCATATCATTGGCAGGGTGTGCCACACAGATGTTCTTTTTTGTAACCTTT GGCATCACTAACTGCTTCCTGCTCACAGCAATGGGATATGACCGCTATGTGGCCATCTGCAACCCCCTGAGATACATGGTTATTATGAAC AAGAGGCTGCGTATCCAACTTGTCCTGGGGGCCTGCAGCATTGGGCTGATTGTAGCAATAACGCAAGTGACATCTGTATTCAGGTTACCC TTCTGTGCTAGAAAGGTGCCCCACTTCTTCTGTGACATCCGCCCTGTGATGAAGCTCTCCTGCATTGACACCACTGTCAATGAAATCCTG ACTTTGATTATCAGTGTGCTGGTGCTTGTTGTACCTATGGGTCTGGTTTTCATTTCTTATGTTCTCATTATCTCTACAATCCTCAAGATT GCTTCAGTTGAGGGCCGGAAGAAGGCTTTTGCCACCTGTGCATCCCACCTCACTGTGGTCATTGTCCACTACAGCTGTGCCTCCATTGCC TACCTCAAGCCCAAGTCAGAGAACACCAGAGAACATGACCAGCTGATCTCGGTGACCTACACTGTCATCACTCCCCTACTGAACCCTGTG GTATACACCCTGAGAAATAAAGAGGTCAAAGATGCTCTGTGCAGGGCTGTTGGTGGGAAGTTTTCCTGACCATGTAGGAAGAGTTCTCCT |
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FusionGenePPI for GABPB2_OR10J1 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| GABPB2 | RYBP, KDM1A, GORASP2, ZDHHC17, CRK, PLCG2, GABPA | OR10J1 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for GABPB2_OR10J1 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for GABPB2_OR10J1 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
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