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Fusion gene ID: 14171 |
FusionGeneSummary for FZR1_NCLN |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: FZR1_NCLN | Fusion gene ID: 14171 | Hgene | Tgene | Gene symbol | FZR1 | NCLN | Gene ID | 51343 | 56926 |
| Gene name | fizzy and cell division cycle 20 related 1 | nicalin | |
| Synonyms | CDC20C|CDH1|FZR|FZR2|HCDH|HCDH1 | NET59 | |
| Cytomap | 19p13.3 | 19p13.3 | |
| Type of gene | protein-coding | protein-coding | |
| Description | fizzy-related protein homologCDC20 homolog 1CDC20-like 1bCDC20-like protein 1cdh1/Hct1 homologfizzy/cell division cycle 20 related 1 | nicalinnicalin homolognicastrin-like protein | |
| Modification date | 20180519 | 20180523 | |
| UniProtAcc | Q9UM11 | Q969V3 | |
| Ensembl transtripts involved in fusion gene | ENST00000441788, ENST00000313639, ENST00000395095, | ENST00000590671, ENST00000246117, ENST00000591062, | |
| Fusion gene scores | * DoF score | 7 X 5 X 7=245 | 2 X 2 X 2=8 |
| # samples | 8 | 2 | |
| ** MAII score | log2(8/245*10)=-1.61470984411521 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(2/8*10)=1.32192809488736 | |
| Context | PubMed: FZR1 [Title/Abstract] AND NCLN [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | Tumor suppressor gene involved fusion gene, in-frame but not retained their domain. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | FZR1 | GO:0031145 | anaphase-promoting complex-dependent catabolic process | 18662541|21596315 |
| Hgene | FZR1 | GO:0072425 | signal transduction involved in G2 DNA damage checkpoint | 18662541 |
| Hgene | FZR1 | GO:1904668 | positive regulation of ubiquitin protein ligase activity | 11459826 |
| Tgene | NCLN | GO:0043254 | regulation of protein complex assembly | 20538592 |
| Tgene | NCLN | GO:0061635 | regulation of protein complex stability | 20538592 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | LUAD | TCGA-55-7903-01A | FZR1 | chr19 | 3523056 | + | NCLN | chr19 | 3201521 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000441788 | ENST00000590671 | FZR1 | chr19 | 3523056 | + | NCLN | chr19 | 3201521 | + |
| In-frame | ENST00000441788 | ENST00000246117 | FZR1 | chr19 | 3523056 | + | NCLN | chr19 | 3201521 | + |
| 5CDS-intron | ENST00000441788 | ENST00000591062 | FZR1 | chr19 | 3523056 | + | NCLN | chr19 | 3201521 | + |
| In-frame | ENST00000313639 | ENST00000590671 | FZR1 | chr19 | 3523056 | + | NCLN | chr19 | 3201521 | + |
| In-frame | ENST00000313639 | ENST00000246117 | FZR1 | chr19 | 3523056 | + | NCLN | chr19 | 3201521 | + |
| 5CDS-intron | ENST00000313639 | ENST00000591062 | FZR1 | chr19 | 3523056 | + | NCLN | chr19 | 3201521 | + |
| In-frame | ENST00000395095 | ENST00000590671 | FZR1 | chr19 | 3523056 | + | NCLN | chr19 | 3201521 | + |
| In-frame | ENST00000395095 | ENST00000246117 | FZR1 | chr19 | 3523056 | + | NCLN | chr19 | 3201521 | + |
| 5CDS-intron | ENST00000395095 | ENST00000591062 | FZR1 | chr19 | 3523056 | + | NCLN | chr19 | 3201521 | + |
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FusionProtFeatures for FZR1_NCLN |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| FZR1 | NCLN |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | >NCLN | chr19:3523056 | chr19:3201521 | ENST00000246117 | + | 4 | 15 | 544_563 | 232 | 564 | Topological domain | Cytoplasmic |
| Tgene | >NCLN | chr19:3523056 | chr19:3201521 | ENST00000246117 | + | 4 | 15 | 523_543 | 232 | 564 | Transmembrane | Helical |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >FZR1 | chr19:3523056 | chr19:3201521 | ENST00000313639 | + | 1 | 11 | 182_222 | 23 | 405 | Repeat | Note=WD 1 |
| Hgene | >FZR1 | chr19:3523056 | chr19:3201521 | ENST00000313639 | + | 1 | 11 | 227_266 | 23 | 405 | Repeat | Note=WD 2 |
| Hgene | >FZR1 | chr19:3523056 | chr19:3201521 | ENST00000313639 | + | 1 | 11 | 269_306 | 23 | 405 | Repeat | Note=WD 3 |
| Hgene | >FZR1 | chr19:3523056 | chr19:3201521 | ENST00000313639 | + | 1 | 11 | 311_350 | 23 | 405 | Repeat | Note=WD 4 |
| Hgene | >FZR1 | chr19:3523056 | chr19:3201521 | ENST00000313639 | + | 1 | 11 | 353_395 | 23 | 405 | Repeat | Note=WD 5 |
| Hgene | >FZR1 | chr19:3523056 | chr19:3201521 | ENST00000313639 | + | 1 | 11 | 397_438 | 23 | 405 | Repeat | Note=WD 6 |
| Hgene | >FZR1 | chr19:3523056 | chr19:3201521 | ENST00000313639 | + | 1 | 11 | 441_480 | 23 | 405 | Repeat | Note=WD 7 |
| Hgene | >FZR1 | chr19:3523056 | chr19:3201521 | ENST00000395095 | + | 1 | 13 | 182_222 | 23 | 497 | Repeat | Note=WD 1 |
| Hgene | >FZR1 | chr19:3523056 | chr19:3201521 | ENST00000395095 | + | 1 | 13 | 227_266 | 23 | 497 | Repeat | Note=WD 2 |
| Hgene | >FZR1 | chr19:3523056 | chr19:3201521 | ENST00000395095 | + | 1 | 13 | 269_306 | 23 | 497 | Repeat | Note=WD 3 |
| Hgene | >FZR1 | chr19:3523056 | chr19:3201521 | ENST00000395095 | + | 1 | 13 | 311_350 | 23 | 497 | Repeat | Note=WD 4 |
| Hgene | >FZR1 | chr19:3523056 | chr19:3201521 | ENST00000395095 | + | 1 | 13 | 353_395 | 23 | 497 | Repeat | Note=WD 5 |
| Hgene | >FZR1 | chr19:3523056 | chr19:3201521 | ENST00000395095 | + | 1 | 13 | 397_438 | 23 | 497 | Repeat | Note=WD 6 |
| Hgene | >FZR1 | chr19:3523056 | chr19:3201521 | ENST00000395095 | + | 1 | 13 | 441_480 | 23 | 497 | Repeat | Note=WD 7 |
| Hgene | >FZR1 | chr19:3523056 | chr19:3201521 | ENST00000441788 | + | 2 | 14 | 182_222 | 23 | 494 | Repeat | Note=WD 1 |
| Hgene | >FZR1 | chr19:3523056 | chr19:3201521 | ENST00000441788 | + | 2 | 14 | 227_266 | 23 | 494 | Repeat | Note=WD 2 |
| Hgene | >FZR1 | chr19:3523056 | chr19:3201521 | ENST00000441788 | + | 2 | 14 | 269_306 | 23 | 494 | Repeat | Note=WD 3 |
| Hgene | >FZR1 | chr19:3523056 | chr19:3201521 | ENST00000441788 | + | 2 | 14 | 311_350 | 23 | 494 | Repeat | Note=WD 4 |
| Hgene | >FZR1 | chr19:3523056 | chr19:3201521 | ENST00000441788 | + | 2 | 14 | 353_395 | 23 | 494 | Repeat | Note=WD 5 |
| Hgene | >FZR1 | chr19:3523056 | chr19:3201521 | ENST00000441788 | + | 2 | 14 | 397_438 | 23 | 494 | Repeat | Note=WD 6 |
| Hgene | >FZR1 | chr19:3523056 | chr19:3201521 | ENST00000441788 | + | 2 | 14 | 441_480 | 23 | 494 | Repeat | Note=WD 7 |
| Tgene | NCLN | chr19:3523056 | chr19:3201521 | ENST00000246117 | + | 4 | 15 | 43_522 | 232 | 564 | Topological domain | Lumenal |
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FusionGeneSequence for FZR1_NCLN |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_FZR1_ENST00000441788_chr19_3523056_+_NCLN_ENST00000590671_chr19_3201521_+_355aa MDQDYERRLLRQIVIQNENTMPRWLSLGADSNGSGVSVLLELARLFSRLYTYKRTHAAYNLLFFASGGGKFNYQGTKRWLEDNLDHTDSS LLQDNVAFVLCLDTVGRGSSLHLHVSKPPREGTLQHAFLRELETVAAHQFPEVRFSMVHKRINLAEDVLAWEHERFAIRRLPAFTLSHLE SHRDGQRSSIMDVRSRVDSKTLTRNTRIIAEALTRVIYNLTEKGTPPDMPVFTEQMQIQQEQLDSVMDWLTNQPRAAQLVDKDSTFLSTL >In-frame_FZR1_ENST00000441788_chr19_3523056_+_NCLN_ENST00000246117_chr19_3201521_+_355aa MDQDYERRLLRQIVIQNENTMPRWLSLGADSNGSGVSVLLELARLFSRLYTYKRTHAAYNLLFFASGGGKFNYQGTKRWLEDNLDHTDSS LLQDNVAFVLCLDTVGRGSSLHLHVSKPPREGTLQHAFLRELETVAAHQFPEVRFSMVHKRINLAEDVLAWEHERFAIRRLPAFTLSHLE SHRDGQRSSIMDVRSRVDSKTLTRNTRIIAEALTRVIYNLTEKGTPPDMPVFTEQMQIQQEQLDSVMDWLTNQPRAAQLVDKDSTFLSTL >In-frame_FZR1_ENST00000313639_chr19_3523056_+_NCLN_ENST00000590671_chr19_3201521_+_355aa MDQDYERRLLRQIVIQNENTMPRWLSLGADSNGSGVSVLLELARLFSRLYTYKRTHAAYNLLFFASGGGKFNYQGTKRWLEDNLDHTDSS LLQDNVAFVLCLDTVGRGSSLHLHVSKPPREGTLQHAFLRELETVAAHQFPEVRFSMVHKRINLAEDVLAWEHERFAIRRLPAFTLSHLE SHRDGQRSSIMDVRSRVDSKTLTRNTRIIAEALTRVIYNLTEKGTPPDMPVFTEQMQIQQEQLDSVMDWLTNQPRAAQLVDKDSTFLSTL >In-frame_FZR1_ENST00000313639_chr19_3523056_+_NCLN_ENST00000246117_chr19_3201521_+_355aa MDQDYERRLLRQIVIQNENTMPRWLSLGADSNGSGVSVLLELARLFSRLYTYKRTHAAYNLLFFASGGGKFNYQGTKRWLEDNLDHTDSS LLQDNVAFVLCLDTVGRGSSLHLHVSKPPREGTLQHAFLRELETVAAHQFPEVRFSMVHKRINLAEDVLAWEHERFAIRRLPAFTLSHLE SHRDGQRSSIMDVRSRVDSKTLTRNTRIIAEALTRVIYNLTEKGTPPDMPVFTEQMQIQQEQLDSVMDWLTNQPRAAQLVDKDSTFLSTL >In-frame_FZR1_ENST00000395095_chr19_3523056_+_NCLN_ENST00000590671_chr19_3201521_+_355aa MDQDYERRLLRQIVIQNENTMPRWLSLGADSNGSGVSVLLELARLFSRLYTYKRTHAAYNLLFFASGGGKFNYQGTKRWLEDNLDHTDSS LLQDNVAFVLCLDTVGRGSSLHLHVSKPPREGTLQHAFLRELETVAAHQFPEVRFSMVHKRINLAEDVLAWEHERFAIRRLPAFTLSHLE SHRDGQRSSIMDVRSRVDSKTLTRNTRIIAEALTRVIYNLTEKGTPPDMPVFTEQMQIQQEQLDSVMDWLTNQPRAAQLVDKDSTFLSTL >In-frame_FZR1_ENST00000395095_chr19_3523056_+_NCLN_ENST00000246117_chr19_3201521_+_355aa MDQDYERRLLRQIVIQNENTMPRWLSLGADSNGSGVSVLLELARLFSRLYTYKRTHAAYNLLFFASGGGKFNYQGTKRWLEDNLDHTDSS LLQDNVAFVLCLDTVGRGSSLHLHVSKPPREGTLQHAFLRELETVAAHQFPEVRFSMVHKRINLAEDVLAWEHERFAIRRLPAFTLSHLE SHRDGQRSSIMDVRSRVDSKTLTRNTRIIAEALTRVIYNLTEKGTPPDMPVFTEQMQIQQEQLDSVMDWLTNQPRAAQLVDKDSTFLSTL |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_FZR1_ENST00000441788_chr19_3523056_+_NCLN_ENST00000590671_chr19_3201521_+_1065nt ATGGACCAGGACTATGAGCGGCGCCTGCTTCGCCAGATCGTCATCCAGAATGAGAACACGATGCCACGCTGGCTGTCGCTGGGCGCGGAC TCCAACGGGAGCGGCGTCTCTGTGCTGCTGGAGCTGGCACGCCTCTTCTCCCGGCTCTACACCTACAAGCGCACGCACGCCGCCTACAAC CTCCTGTTCTTTGCGTCTGGAGGAGGCAAGTTTAACTACCAGGGAACCAAGCGCTGGCTGGAAGACAACCTGGACCACACAGACTCCAGC CTGCTTCAGGACAATGTGGCCTTCGTGCTGTGCCTGGACACCGTGGGCCGGGGCAGCAGCCTGCACCTGCACGTGTCCAAGCCGCCTCGG GAGGGCACCCTGCAGCACGCCTTCCTGCGGGAGCTGGAGACGGTGGCCGCGCACCAGTTCCCTGAGGTACGGTTCTCCATGGTGCACAAG CGGATCAACCTGGCGGAGGACGTGCTGGCCTGGGAGCACGAGCGCTTCGCCATCCGCCGACTGCCCGCCTTCACGCTGTCCCACCTGGAG AGCCACCGTGACGGCCAGCGCAGCAGCATCATGGACGTGCGGTCCCGGGTGGATTCTAAGACCCTGACCCGTAACACGAGGATCATTGCA GAGGCCCTGACTCGAGTCATCTACAACCTGACAGAGAAGGGGACACCCCCAGACATGCCGGTGTTCACAGAGCAGATGCAGATCCAGCAG GAGCAGCTGGACTCGGTGATGGACTGGCTCACCAACCAGCCGCGGGCCGCGCAGCTGGTGGACAAGGACAGCACCTTCCTCAGCACGCTG GAGCACCACCTGAGCCGCTACCTGAAGGACGTGAAGCAGCACCACGTCAAGGCTGACAAGCGGGACCCAGAGTTTGTCTTCTACGACCAG CTGAAGCAAGTGATGAATGCGTACAGAGTCAAGCCGGCCGTCTTTGACCTGCTCCTGGCTGTTGGCATTGCTGCCTACCTCGGCATGGCC >In-frame_FZR1_ENST00000441788_chr19_3523056_+_NCLN_ENST00000246117_chr19_3201521_+_1065nt ATGGACCAGGACTATGAGCGGCGCCTGCTTCGCCAGATCGTCATCCAGAATGAGAACACGATGCCACGCTGGCTGTCGCTGGGCGCGGAC TCCAACGGGAGCGGCGTCTCTGTGCTGCTGGAGCTGGCACGCCTCTTCTCCCGGCTCTACACCTACAAGCGCACGCACGCCGCCTACAAC CTCCTGTTCTTTGCGTCTGGAGGAGGCAAGTTTAACTACCAGGGAACCAAGCGCTGGCTGGAAGACAACCTGGACCACACAGACTCCAGC CTGCTTCAGGACAATGTGGCCTTCGTGCTGTGCCTGGACACCGTGGGCCGGGGCAGCAGCCTGCACCTGCACGTGTCCAAGCCGCCTCGG GAGGGCACCCTGCAGCACGCCTTCCTGCGGGAGCTGGAGACGGTGGCCGCGCACCAGTTCCCTGAGGTACGGTTCTCCATGGTGCACAAG CGGATCAACCTGGCGGAGGACGTGCTGGCCTGGGAGCACGAGCGCTTCGCCATCCGCCGACTGCCCGCCTTCACGCTGTCCCACCTGGAG AGCCACCGTGACGGCCAGCGCAGCAGCATCATGGACGTGCGGTCCCGGGTGGATTCTAAGACCCTGACCCGTAACACGAGGATCATTGCA GAGGCCCTGACTCGAGTCATCTACAACCTGACAGAGAAGGGGACACCCCCAGACATGCCGGTGTTCACAGAGCAGATGCAGATCCAGCAG GAGCAGCTGGACTCGGTGATGGACTGGCTCACCAACCAGCCGCGGGCCGCGCAGCTGGTGGACAAGGACAGCACCTTCCTCAGCACGCTG GAGCACCACCTGAGCCGCTACCTGAAGGACGTGAAGCAGCACCACGTCAAGGCTGACAAGCGGGACCCAGAGTTTGTCTTCTACGACCAG CTGAAGCAAGTGATGAATGCGTACAGAGTCAAGCCGGCCGTCTTTGACCTGCTCCTGGCTGTTGGCATTGCTGCCTACCTCGGCATGGCC >In-frame_FZR1_ENST00000313639_chr19_3523056_+_NCLN_ENST00000590671_chr19_3201521_+_1065nt ATGGACCAGGACTATGAGCGGCGCCTGCTTCGCCAGATCGTCATCCAGAATGAGAACACGATGCCACGCTGGCTGTCGCTGGGCGCGGAC TCCAACGGGAGCGGCGTCTCTGTGCTGCTGGAGCTGGCACGCCTCTTCTCCCGGCTCTACACCTACAAGCGCACGCACGCCGCCTACAAC CTCCTGTTCTTTGCGTCTGGAGGAGGCAAGTTTAACTACCAGGGAACCAAGCGCTGGCTGGAAGACAACCTGGACCACACAGACTCCAGC CTGCTTCAGGACAATGTGGCCTTCGTGCTGTGCCTGGACACCGTGGGCCGGGGCAGCAGCCTGCACCTGCACGTGTCCAAGCCGCCTCGG GAGGGCACCCTGCAGCACGCCTTCCTGCGGGAGCTGGAGACGGTGGCCGCGCACCAGTTCCCTGAGGTACGGTTCTCCATGGTGCACAAG CGGATCAACCTGGCGGAGGACGTGCTGGCCTGGGAGCACGAGCGCTTCGCCATCCGCCGACTGCCCGCCTTCACGCTGTCCCACCTGGAG AGCCACCGTGACGGCCAGCGCAGCAGCATCATGGACGTGCGGTCCCGGGTGGATTCTAAGACCCTGACCCGTAACACGAGGATCATTGCA GAGGCCCTGACTCGAGTCATCTACAACCTGACAGAGAAGGGGACACCCCCAGACATGCCGGTGTTCACAGAGCAGATGCAGATCCAGCAG GAGCAGCTGGACTCGGTGATGGACTGGCTCACCAACCAGCCGCGGGCCGCGCAGCTGGTGGACAAGGACAGCACCTTCCTCAGCACGCTG GAGCACCACCTGAGCCGCTACCTGAAGGACGTGAAGCAGCACCACGTCAAGGCTGACAAGCGGGACCCAGAGTTTGTCTTCTACGACCAG CTGAAGCAAGTGATGAATGCGTACAGAGTCAAGCCGGCCGTCTTTGACCTGCTCCTGGCTGTTGGCATTGCTGCCTACCTCGGCATGGCC >In-frame_FZR1_ENST00000313639_chr19_3523056_+_NCLN_ENST00000246117_chr19_3201521_+_1065nt ATGGACCAGGACTATGAGCGGCGCCTGCTTCGCCAGATCGTCATCCAGAATGAGAACACGATGCCACGCTGGCTGTCGCTGGGCGCGGAC TCCAACGGGAGCGGCGTCTCTGTGCTGCTGGAGCTGGCACGCCTCTTCTCCCGGCTCTACACCTACAAGCGCACGCACGCCGCCTACAAC CTCCTGTTCTTTGCGTCTGGAGGAGGCAAGTTTAACTACCAGGGAACCAAGCGCTGGCTGGAAGACAACCTGGACCACACAGACTCCAGC CTGCTTCAGGACAATGTGGCCTTCGTGCTGTGCCTGGACACCGTGGGCCGGGGCAGCAGCCTGCACCTGCACGTGTCCAAGCCGCCTCGG GAGGGCACCCTGCAGCACGCCTTCCTGCGGGAGCTGGAGACGGTGGCCGCGCACCAGTTCCCTGAGGTACGGTTCTCCATGGTGCACAAG CGGATCAACCTGGCGGAGGACGTGCTGGCCTGGGAGCACGAGCGCTTCGCCATCCGCCGACTGCCCGCCTTCACGCTGTCCCACCTGGAG AGCCACCGTGACGGCCAGCGCAGCAGCATCATGGACGTGCGGTCCCGGGTGGATTCTAAGACCCTGACCCGTAACACGAGGATCATTGCA GAGGCCCTGACTCGAGTCATCTACAACCTGACAGAGAAGGGGACACCCCCAGACATGCCGGTGTTCACAGAGCAGATGCAGATCCAGCAG GAGCAGCTGGACTCGGTGATGGACTGGCTCACCAACCAGCCGCGGGCCGCGCAGCTGGTGGACAAGGACAGCACCTTCCTCAGCACGCTG GAGCACCACCTGAGCCGCTACCTGAAGGACGTGAAGCAGCACCACGTCAAGGCTGACAAGCGGGACCCAGAGTTTGTCTTCTACGACCAG CTGAAGCAAGTGATGAATGCGTACAGAGTCAAGCCGGCCGTCTTTGACCTGCTCCTGGCTGTTGGCATTGCTGCCTACCTCGGCATGGCC >In-frame_FZR1_ENST00000395095_chr19_3523056_+_NCLN_ENST00000590671_chr19_3201521_+_1065nt ATGGACCAGGACTATGAGCGGCGCCTGCTTCGCCAGATCGTCATCCAGAATGAGAACACGATGCCACGCTGGCTGTCGCTGGGCGCGGAC TCCAACGGGAGCGGCGTCTCTGTGCTGCTGGAGCTGGCACGCCTCTTCTCCCGGCTCTACACCTACAAGCGCACGCACGCCGCCTACAAC CTCCTGTTCTTTGCGTCTGGAGGAGGCAAGTTTAACTACCAGGGAACCAAGCGCTGGCTGGAAGACAACCTGGACCACACAGACTCCAGC CTGCTTCAGGACAATGTGGCCTTCGTGCTGTGCCTGGACACCGTGGGCCGGGGCAGCAGCCTGCACCTGCACGTGTCCAAGCCGCCTCGG GAGGGCACCCTGCAGCACGCCTTCCTGCGGGAGCTGGAGACGGTGGCCGCGCACCAGTTCCCTGAGGTACGGTTCTCCATGGTGCACAAG CGGATCAACCTGGCGGAGGACGTGCTGGCCTGGGAGCACGAGCGCTTCGCCATCCGCCGACTGCCCGCCTTCACGCTGTCCCACCTGGAG AGCCACCGTGACGGCCAGCGCAGCAGCATCATGGACGTGCGGTCCCGGGTGGATTCTAAGACCCTGACCCGTAACACGAGGATCATTGCA GAGGCCCTGACTCGAGTCATCTACAACCTGACAGAGAAGGGGACACCCCCAGACATGCCGGTGTTCACAGAGCAGATGCAGATCCAGCAG GAGCAGCTGGACTCGGTGATGGACTGGCTCACCAACCAGCCGCGGGCCGCGCAGCTGGTGGACAAGGACAGCACCTTCCTCAGCACGCTG GAGCACCACCTGAGCCGCTACCTGAAGGACGTGAAGCAGCACCACGTCAAGGCTGACAAGCGGGACCCAGAGTTTGTCTTCTACGACCAG CTGAAGCAAGTGATGAATGCGTACAGAGTCAAGCCGGCCGTCTTTGACCTGCTCCTGGCTGTTGGCATTGCTGCCTACCTCGGCATGGCC >In-frame_FZR1_ENST00000395095_chr19_3523056_+_NCLN_ENST00000246117_chr19_3201521_+_1065nt ATGGACCAGGACTATGAGCGGCGCCTGCTTCGCCAGATCGTCATCCAGAATGAGAACACGATGCCACGCTGGCTGTCGCTGGGCGCGGAC TCCAACGGGAGCGGCGTCTCTGTGCTGCTGGAGCTGGCACGCCTCTTCTCCCGGCTCTACACCTACAAGCGCACGCACGCCGCCTACAAC CTCCTGTTCTTTGCGTCTGGAGGAGGCAAGTTTAACTACCAGGGAACCAAGCGCTGGCTGGAAGACAACCTGGACCACACAGACTCCAGC CTGCTTCAGGACAATGTGGCCTTCGTGCTGTGCCTGGACACCGTGGGCCGGGGCAGCAGCCTGCACCTGCACGTGTCCAAGCCGCCTCGG GAGGGCACCCTGCAGCACGCCTTCCTGCGGGAGCTGGAGACGGTGGCCGCGCACCAGTTCCCTGAGGTACGGTTCTCCATGGTGCACAAG CGGATCAACCTGGCGGAGGACGTGCTGGCCTGGGAGCACGAGCGCTTCGCCATCCGCCGACTGCCCGCCTTCACGCTGTCCCACCTGGAG AGCCACCGTGACGGCCAGCGCAGCAGCATCATGGACGTGCGGTCCCGGGTGGATTCTAAGACCCTGACCCGTAACACGAGGATCATTGCA GAGGCCCTGACTCGAGTCATCTACAACCTGACAGAGAAGGGGACACCCCCAGACATGCCGGTGTTCACAGAGCAGATGCAGATCCAGCAG GAGCAGCTGGACTCGGTGATGGACTGGCTCACCAACCAGCCGCGGGCCGCGCAGCTGGTGGACAAGGACAGCACCTTCCTCAGCACGCTG GAGCACCACCTGAGCCGCTACCTGAAGGACGTGAAGCAGCACCACGTCAAGGCTGACAAGCGGGACCCAGAGTTTGTCTTCTACGACCAG CTGAAGCAAGTGATGAATGCGTACAGAGTCAAGCCGGCCGTCTTTGACCTGCTCCTGGCTGTTGGCATTGCTGCCTACCTCGGCATGGCC |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_FZR1_ENST00000441788_chr19_3523056_+_NCLN_ENST00000590671_chr19_3201521_+_1469nt GGCCGGGCGCGCGCGGCGGAGGGAGGGAGCCGGGAGGCAGCGGAGGAGCGACCGCCGCCATATTAGGGACCGCGGAGCCCGGGATCCCGT CAGCGGCGGCCGCGGCCGGGCCTGCGGGAGCTGCGGAGGCCGGAGGCGGGCGCTGTGCGGTGCCAGGAGAGGCGGGGTCGGCGGGAGCCA GCGAGCCACGGGAGCGAGCCAGGCTAACCTTGCCGCGGGCCGAGCCCTGCCTCGCCATGGACCAGGACTATGAGCGGCGCCTGCTTCGCC AGATCGTCATCCAGAATGAGAACACGATGCCACGCTGGCTGTCGCTGGGCGCGGACTCCAACGGGAGCGGCGTCTCTGTGCTGCTGGAGC TGGCACGCCTCTTCTCCCGGCTCTACACCTACAAGCGCACGCACGCCGCCTACAACCTCCTGTTCTTTGCGTCTGGAGGAGGCAAGTTTA ACTACCAGGGAACCAAGCGCTGGCTGGAAGACAACCTGGACCACACAGACTCCAGCCTGCTTCAGGACAATGTGGCCTTCGTGCTGTGCC TGGACACCGTGGGCCGGGGCAGCAGCCTGCACCTGCACGTGTCCAAGCCGCCTCGGGAGGGCACCCTGCAGCACGCCTTCCTGCGGGAGC TGGAGACGGTGGCCGCGCACCAGTTCCCTGAGGTACGGTTCTCCATGGTGCACAAGCGGATCAACCTGGCGGAGGACGTGCTGGCCTGGG AGCACGAGCGCTTCGCCATCCGCCGACTGCCCGCCTTCACGCTGTCCCACCTGGAGAGCCACCGTGACGGCCAGCGCAGCAGCATCATGG ACGTGCGGTCCCGGGTGGATTCTAAGACCCTGACCCGTAACACGAGGATCATTGCAGAGGCCCTGACTCGAGTCATCTACAACCTGACAG AGAAGGGGACACCCCCAGACATGCCGGTGTTCACAGAGCAGATGCAGATCCAGCAGGAGCAGCTGGACTCGGTGATGGACTGGCTCACCA ACCAGCCGCGGGCCGCGCAGCTGGTGGACAAGGACAGCACCTTCCTCAGCACGCTGGAGCACCACCTGAGCCGCTACCTGAAGGACGTGA AGCAGCACCACGTCAAGGCTGACAAGCGGGACCCAGAGTTTGTCTTCTACGACCAGCTGAAGCAAGTGATGAATGCGTACAGAGTCAAGC CGGCCGTCTTTGACCTGCTCCTGGCTGTTGGCATTGCTGCCTACCTCGGCATGGCCTACGTGGCTGTCCAGCACTTCAGCCTCCTCTACA AGACCGTCCAGAGGCTGCTCGTGAAGGCCAAGACACAGTGACACAGCCACCCCCACAGCCGGAGCCCCCGCCGCTCCACAGTCCCTGGGG CCGAGCACGAGTGAGTGGACACTGCCCCGCCGCGGGCGGCCCTGCAGGGACAGGGGCCCTCTCCCTCCCCGGCGGTGGTTGGAACACTGA >In-frame_FZR1_ENST00000441788_chr19_3523056_+_NCLN_ENST00000246117_chr19_3201521_+_3183nt GGCCGGGCGCGCGCGGCGGAGGGAGGGAGCCGGGAGGCAGCGGAGGAGCGACCGCCGCCATATTAGGGACCGCGGAGCCCGGGATCCCGT CAGCGGCGGCCGCGGCCGGGCCTGCGGGAGCTGCGGAGGCCGGAGGCGGGCGCTGTGCGGTGCCAGGAGAGGCGGGGTCGGCGGGAGCCA GCGAGCCACGGGAGCGAGCCAGGCTAACCTTGCCGCGGGCCGAGCCCTGCCTCGCCATGGACCAGGACTATGAGCGGCGCCTGCTTCGCC AGATCGTCATCCAGAATGAGAACACGATGCCACGCTGGCTGTCGCTGGGCGCGGACTCCAACGGGAGCGGCGTCTCTGTGCTGCTGGAGC TGGCACGCCTCTTCTCCCGGCTCTACACCTACAAGCGCACGCACGCCGCCTACAACCTCCTGTTCTTTGCGTCTGGAGGAGGCAAGTTTA ACTACCAGGGAACCAAGCGCTGGCTGGAAGACAACCTGGACCACACAGACTCCAGCCTGCTTCAGGACAATGTGGCCTTCGTGCTGTGCC TGGACACCGTGGGCCGGGGCAGCAGCCTGCACCTGCACGTGTCCAAGCCGCCTCGGGAGGGCACCCTGCAGCACGCCTTCCTGCGGGAGC TGGAGACGGTGGCCGCGCACCAGTTCCCTGAGGTACGGTTCTCCATGGTGCACAAGCGGATCAACCTGGCGGAGGACGTGCTGGCCTGGG AGCACGAGCGCTTCGCCATCCGCCGACTGCCCGCCTTCACGCTGTCCCACCTGGAGAGCCACCGTGACGGCCAGCGCAGCAGCATCATGG ACGTGCGGTCCCGGGTGGATTCTAAGACCCTGACCCGTAACACGAGGATCATTGCAGAGGCCCTGACTCGAGTCATCTACAACCTGACAG AGAAGGGGACACCCCCAGACATGCCGGTGTTCACAGAGCAGATGCAGATCCAGCAGGAGCAGCTGGACTCGGTGATGGACTGGCTCACCA ACCAGCCGCGGGCCGCGCAGCTGGTGGACAAGGACAGCACCTTCCTCAGCACGCTGGAGCACCACCTGAGCCGCTACCTGAAGGACGTGA AGCAGCACCACGTCAAGGCTGACAAGCGGGACCCAGAGTTTGTCTTCTACGACCAGCTGAAGCAAGTGATGAATGCGTACAGAGTCAAGC CGGCCGTCTTTGACCTGCTCCTGGCTGTTGGCATTGCTGCCTACCTCGGCATGGCCTACGTGGCTGTCCAGCACTTCAGCCTCCTCTACA AGACCGTCCAGAGGCTGCTCGTGAAGGCCAAGACACAGTGACACAGCCACCCCCACAGCCGGAGCCCCCGCCGCTCCACAGTCCCTGGGG CCGAGCACGAGTGAGTGGACACTGCCCCGCCGCGGGCGGCCCTGCAGGGACAGGGGCCCTCTCCCTCCCCGGCGGTGGTTGGAACACTGA ATTACAGAGCTTTTTTCTGTTGCTCTCCGAGACTGGGGGGGGATTGTTTCTTCTTTTCCTTGTCTTTGAACTTCCTTGGAGGAGAGCTTG GGAGACGTCCCGGGGCCAGGCTACGGACTTGCGGACGAGCCCCCCAGTCCTGGGAGCCGGCCGCCCTCGGTCTGGTGTAAGCACACATGC ACGATTAAAGAGGAGACGCCGGGACCCCCTGCCCGATCGCGCGCGGCCTCCGCCCACCGCCTCCTGCCGCAAGGGGCCTGGACTGCAGGC CTGACCTGCTCCCTGCTCCGTGTCTGTCCTAGGACGTCCCCTCCCGCTCCCCGATGGTGGCGTGGACATGGTTATTTATCTCTGCTCCTT CTTGCCTGGAGGAGGGCAGTGCCAGCCCTGGGGTTCTGGGATTCCAGCCCTCCTGGAGCCTTTTGTTCCCCATGTGGTCTCAGTGACCCG TCCCCCTGACAGTGGGCTCGGGGAGCTGCATCACCCAGCCTTCCCCTTCTCCGACTGCAGGGTCTGATGTCATCATTGACAGCCTTTGCT TCGTGGGGGCCTGGCAGGGCCCCTGCCTCCCCGACCCCCGACCCACTGCAAATCCCCGTTCCCCTGCACTCCTCTTCTCCCAGCCCATCC CTCCGGCCCCTGTGCCTCTGCGGCCCCAGCCCAGCTCCCAGGGCCGTCACCTGCTTGGCCCTGGCCCAGCTCCCTGCCCTGAGTCCTGAG CCAGTGCCTGGTGTTTCCTGGGCTCGGTACTGGGCCCCCAGGCCATCCAGGCTTTGCCACGGCCAGTTGGTCCTCCCTGGGGAACTGGGT GCGGGTGGAGTACTGGGAGGCAGGAGGTGGCCCGGGGAGGCCTTGTGGCTCCTCCCCTCGCTCCTCGCCCTGGGCCTCAGCTTCCTCATC AATAGAAAGGATGTGTTCGGGGTGGGGGCGTCAGGTGAGAACGTTTGCTGGGAAGGAGAGGACTTGGGGCATGGCCTCTGGGGCCACCCT TCCTGGAACTCAGAGAGGAAGGTCCGGGCCCTCGGGAAGCCTTGGACAGAACCCTCCACCCCGCAGACCAGGCGTCGTGTGTGTGTGGGA GAGAAGGAGGCCCGTGTTGAGCTCAGGGAGACCCCGGTGTGTCCGTTCTTTAGCAATATAACCTACCCAGTGCGTGCCGAGCAGGCTTGG TGGGGAAGGGACTTGAGCTGGGCAAGTCCTGGCCTGGCACCCGCAGCCGTCTCCCTTCCGTGGCCCAGGGAGGTGTTTGCTGTCCGAAGG ACCTGGGCCGGCCCATGGGAGCCTGGGGTTCTGTCCAGATAGGACCAGGGGGTCTCACTTTGGCCACCAGTTCTTCGGCCAGCACCTCTG CCCTCCAGAACCTGCAGCCTGGAGGGGTGAGGGGACAACCACCCCTCTTTCCTCCAGGTTGGCAGGGGACCCTCTTCTCCCGTCTGCCCT GCGGGTTGCCCGCCTCCTCCAGAGACTTGCCCAAGGGCCCATCACCACTGGCCTCTGGGCACTTGTGCTGAGACTCTGGGACCCAGGCAG CTGCCACCTTGTCACCATGAGAGAATTTGGGGAGTGCTTGCATGCTAGCCAGCAGGCTCCTGTCTGGGTGCCACGGGGCCAGCATTTTGG AGGGAGCTTCCTTCCTTCCTTCCTGGACAGGTCGTCATGATGGATGCACTGACTGACCGTCTGGGGCTCAGGCTGGTGTGGGATGCAGCC >In-frame_FZR1_ENST00000313639_chr19_3523056_+_NCLN_ENST00000590671_chr19_3201521_+_1233nt ATGGACCAGGACTATGAGCGGCGCCTGCTTCGCCAGATCGTCATCCAGAATGAGAACACGATGCCACGCTGGCTGTCGCTGGGCGCGGAC TCCAACGGGAGCGGCGTCTCTGTGCTGCTGGAGCTGGCACGCCTCTTCTCCCGGCTCTACACCTACAAGCGCACGCACGCCGCCTACAAC CTCCTGTTCTTTGCGTCTGGAGGAGGCAAGTTTAACTACCAGGGAACCAAGCGCTGGCTGGAAGACAACCTGGACCACACAGACTCCAGC CTGCTTCAGGACAATGTGGCCTTCGTGCTGTGCCTGGACACCGTGGGCCGGGGCAGCAGCCTGCACCTGCACGTGTCCAAGCCGCCTCGG GAGGGCACCCTGCAGCACGCCTTCCTGCGGGAGCTGGAGACGGTGGCCGCGCACCAGTTCCCTGAGGTACGGTTCTCCATGGTGCACAAG CGGATCAACCTGGCGGAGGACGTGCTGGCCTGGGAGCACGAGCGCTTCGCCATCCGCCGACTGCCCGCCTTCACGCTGTCCCACCTGGAG AGCCACCGTGACGGCCAGCGCAGCAGCATCATGGACGTGCGGTCCCGGGTGGATTCTAAGACCCTGACCCGTAACACGAGGATCATTGCA GAGGCCCTGACTCGAGTCATCTACAACCTGACAGAGAAGGGGACACCCCCAGACATGCCGGTGTTCACAGAGCAGATGCAGATCCAGCAG GAGCAGCTGGACTCGGTGATGGACTGGCTCACCAACCAGCCGCGGGCCGCGCAGCTGGTGGACAAGGACAGCACCTTCCTCAGCACGCTG GAGCACCACCTGAGCCGCTACCTGAAGGACGTGAAGCAGCACCACGTCAAGGCTGACAAGCGGGACCCAGAGTTTGTCTTCTACGACCAG CTGAAGCAAGTGATGAATGCGTACAGAGTCAAGCCGGCCGTCTTTGACCTGCTCCTGGCTGTTGGCATTGCTGCCTACCTCGGCATGGCC TACGTGGCTGTCCAGCACTTCAGCCTCCTCTACAAGACCGTCCAGAGGCTGCTCGTGAAGGCCAAGACACAGTGACACAGCCACCCCCAC AGCCGGAGCCCCCGCCGCTCCACAGTCCCTGGGGCCGAGCACGAGTGAGTGGACACTGCCCCGCCGCGGGCGGCCCTGCAGGGACAGGGG >In-frame_FZR1_ENST00000313639_chr19_3523056_+_NCLN_ENST00000246117_chr19_3201521_+_2947nt ATGGACCAGGACTATGAGCGGCGCCTGCTTCGCCAGATCGTCATCCAGAATGAGAACACGATGCCACGCTGGCTGTCGCTGGGCGCGGAC TCCAACGGGAGCGGCGTCTCTGTGCTGCTGGAGCTGGCACGCCTCTTCTCCCGGCTCTACACCTACAAGCGCACGCACGCCGCCTACAAC CTCCTGTTCTTTGCGTCTGGAGGAGGCAAGTTTAACTACCAGGGAACCAAGCGCTGGCTGGAAGACAACCTGGACCACACAGACTCCAGC CTGCTTCAGGACAATGTGGCCTTCGTGCTGTGCCTGGACACCGTGGGCCGGGGCAGCAGCCTGCACCTGCACGTGTCCAAGCCGCCTCGG GAGGGCACCCTGCAGCACGCCTTCCTGCGGGAGCTGGAGACGGTGGCCGCGCACCAGTTCCCTGAGGTACGGTTCTCCATGGTGCACAAG CGGATCAACCTGGCGGAGGACGTGCTGGCCTGGGAGCACGAGCGCTTCGCCATCCGCCGACTGCCCGCCTTCACGCTGTCCCACCTGGAG AGCCACCGTGACGGCCAGCGCAGCAGCATCATGGACGTGCGGTCCCGGGTGGATTCTAAGACCCTGACCCGTAACACGAGGATCATTGCA GAGGCCCTGACTCGAGTCATCTACAACCTGACAGAGAAGGGGACACCCCCAGACATGCCGGTGTTCACAGAGCAGATGCAGATCCAGCAG GAGCAGCTGGACTCGGTGATGGACTGGCTCACCAACCAGCCGCGGGCCGCGCAGCTGGTGGACAAGGACAGCACCTTCCTCAGCACGCTG GAGCACCACCTGAGCCGCTACCTGAAGGACGTGAAGCAGCACCACGTCAAGGCTGACAAGCGGGACCCAGAGTTTGTCTTCTACGACCAG CTGAAGCAAGTGATGAATGCGTACAGAGTCAAGCCGGCCGTCTTTGACCTGCTCCTGGCTGTTGGCATTGCTGCCTACCTCGGCATGGCC TACGTGGCTGTCCAGCACTTCAGCCTCCTCTACAAGACCGTCCAGAGGCTGCTCGTGAAGGCCAAGACACAGTGACACAGCCACCCCCAC AGCCGGAGCCCCCGCCGCTCCACAGTCCCTGGGGCCGAGCACGAGTGAGTGGACACTGCCCCGCCGCGGGCGGCCCTGCAGGGACAGGGG CCCTCTCCCTCCCCGGCGGTGGTTGGAACACTGAATTACAGAGCTTTTTTCTGTTGCTCTCCGAGACTGGGGGGGGATTGTTTCTTCTTT TCCTTGTCTTTGAACTTCCTTGGAGGAGAGCTTGGGAGACGTCCCGGGGCCAGGCTACGGACTTGCGGACGAGCCCCCCAGTCCTGGGAG CCGGCCGCCCTCGGTCTGGTGTAAGCACACATGCACGATTAAAGAGGAGACGCCGGGACCCCCTGCCCGATCGCGCGCGGCCTCCGCCCA CCGCCTCCTGCCGCAAGGGGCCTGGACTGCAGGCCTGACCTGCTCCCTGCTCCGTGTCTGTCCTAGGACGTCCCCTCCCGCTCCCCGATG GTGGCGTGGACATGGTTATTTATCTCTGCTCCTTCTTGCCTGGAGGAGGGCAGTGCCAGCCCTGGGGTTCTGGGATTCCAGCCCTCCTGG AGCCTTTTGTTCCCCATGTGGTCTCAGTGACCCGTCCCCCTGACAGTGGGCTCGGGGAGCTGCATCACCCAGCCTTCCCCTTCTCCGACT GCAGGGTCTGATGTCATCATTGACAGCCTTTGCTTCGTGGGGGCCTGGCAGGGCCCCTGCCTCCCCGACCCCCGACCCACTGCAAATCCC CGTTCCCCTGCACTCCTCTTCTCCCAGCCCATCCCTCCGGCCCCTGTGCCTCTGCGGCCCCAGCCCAGCTCCCAGGGCCGTCACCTGCTT GGCCCTGGCCCAGCTCCCTGCCCTGAGTCCTGAGCCAGTGCCTGGTGTTTCCTGGGCTCGGTACTGGGCCCCCAGGCCATCCAGGCTTTG CCACGGCCAGTTGGTCCTCCCTGGGGAACTGGGTGCGGGTGGAGTACTGGGAGGCAGGAGGTGGCCCGGGGAGGCCTTGTGGCTCCTCCC CTCGCTCCTCGCCCTGGGCCTCAGCTTCCTCATCAATAGAAAGGATGTGTTCGGGGTGGGGGCGTCAGGTGAGAACGTTTGCTGGGAAGG AGAGGACTTGGGGCATGGCCTCTGGGGCCACCCTTCCTGGAACTCAGAGAGGAAGGTCCGGGCCCTCGGGAAGCCTTGGACAGAACCCTC CACCCCGCAGACCAGGCGTCGTGTGTGTGTGGGAGAGAAGGAGGCCCGTGTTGAGCTCAGGGAGACCCCGGTGTGTCCGTTCTTTAGCAA TATAACCTACCCAGTGCGTGCCGAGCAGGCTTGGTGGGGAAGGGACTTGAGCTGGGCAAGTCCTGGCCTGGCACCCGCAGCCGTCTCCCT TCCGTGGCCCAGGGAGGTGTTTGCTGTCCGAAGGACCTGGGCCGGCCCATGGGAGCCTGGGGTTCTGTCCAGATAGGACCAGGGGGTCTC ACTTTGGCCACCAGTTCTTCGGCCAGCACCTCTGCCCTCCAGAACCTGCAGCCTGGAGGGGTGAGGGGACAACCACCCCTCTTTCCTCCA GGTTGGCAGGGGACCCTCTTCTCCCGTCTGCCCTGCGGGTTGCCCGCCTCCTCCAGAGACTTGCCCAAGGGCCCATCACCACTGGCCTCT GGGCACTTGTGCTGAGACTCTGGGACCCAGGCAGCTGCCACCTTGTCACCATGAGAGAATTTGGGGAGTGCTTGCATGCTAGCCAGCAGG CTCCTGTCTGGGTGCCACGGGGCCAGCATTTTGGAGGGAGCTTCCTTCCTTCCTTCCTGGACAGGTCGTCATGATGGATGCACTGACTGA >In-frame_FZR1_ENST00000395095_chr19_3523056_+_NCLN_ENST00000590671_chr19_3201521_+_1233nt ATGGACCAGGACTATGAGCGGCGCCTGCTTCGCCAGATCGTCATCCAGAATGAGAACACGATGCCACGCTGGCTGTCGCTGGGCGCGGAC TCCAACGGGAGCGGCGTCTCTGTGCTGCTGGAGCTGGCACGCCTCTTCTCCCGGCTCTACACCTACAAGCGCACGCACGCCGCCTACAAC CTCCTGTTCTTTGCGTCTGGAGGAGGCAAGTTTAACTACCAGGGAACCAAGCGCTGGCTGGAAGACAACCTGGACCACACAGACTCCAGC CTGCTTCAGGACAATGTGGCCTTCGTGCTGTGCCTGGACACCGTGGGCCGGGGCAGCAGCCTGCACCTGCACGTGTCCAAGCCGCCTCGG GAGGGCACCCTGCAGCACGCCTTCCTGCGGGAGCTGGAGACGGTGGCCGCGCACCAGTTCCCTGAGGTACGGTTCTCCATGGTGCACAAG CGGATCAACCTGGCGGAGGACGTGCTGGCCTGGGAGCACGAGCGCTTCGCCATCCGCCGACTGCCCGCCTTCACGCTGTCCCACCTGGAG AGCCACCGTGACGGCCAGCGCAGCAGCATCATGGACGTGCGGTCCCGGGTGGATTCTAAGACCCTGACCCGTAACACGAGGATCATTGCA GAGGCCCTGACTCGAGTCATCTACAACCTGACAGAGAAGGGGACACCCCCAGACATGCCGGTGTTCACAGAGCAGATGCAGATCCAGCAG GAGCAGCTGGACTCGGTGATGGACTGGCTCACCAACCAGCCGCGGGCCGCGCAGCTGGTGGACAAGGACAGCACCTTCCTCAGCACGCTG GAGCACCACCTGAGCCGCTACCTGAAGGACGTGAAGCAGCACCACGTCAAGGCTGACAAGCGGGACCCAGAGTTTGTCTTCTACGACCAG CTGAAGCAAGTGATGAATGCGTACAGAGTCAAGCCGGCCGTCTTTGACCTGCTCCTGGCTGTTGGCATTGCTGCCTACCTCGGCATGGCC TACGTGGCTGTCCAGCACTTCAGCCTCCTCTACAAGACCGTCCAGAGGCTGCTCGTGAAGGCCAAGACACAGTGACACAGCCACCCCCAC AGCCGGAGCCCCCGCCGCTCCACAGTCCCTGGGGCCGAGCACGAGTGAGTGGACACTGCCCCGCCGCGGGCGGCCCTGCAGGGACAGGGG >In-frame_FZR1_ENST00000395095_chr19_3523056_+_NCLN_ENST00000246117_chr19_3201521_+_2947nt ATGGACCAGGACTATGAGCGGCGCCTGCTTCGCCAGATCGTCATCCAGAATGAGAACACGATGCCACGCTGGCTGTCGCTGGGCGCGGAC TCCAACGGGAGCGGCGTCTCTGTGCTGCTGGAGCTGGCACGCCTCTTCTCCCGGCTCTACACCTACAAGCGCACGCACGCCGCCTACAAC CTCCTGTTCTTTGCGTCTGGAGGAGGCAAGTTTAACTACCAGGGAACCAAGCGCTGGCTGGAAGACAACCTGGACCACACAGACTCCAGC CTGCTTCAGGACAATGTGGCCTTCGTGCTGTGCCTGGACACCGTGGGCCGGGGCAGCAGCCTGCACCTGCACGTGTCCAAGCCGCCTCGG GAGGGCACCCTGCAGCACGCCTTCCTGCGGGAGCTGGAGACGGTGGCCGCGCACCAGTTCCCTGAGGTACGGTTCTCCATGGTGCACAAG CGGATCAACCTGGCGGAGGACGTGCTGGCCTGGGAGCACGAGCGCTTCGCCATCCGCCGACTGCCCGCCTTCACGCTGTCCCACCTGGAG AGCCACCGTGACGGCCAGCGCAGCAGCATCATGGACGTGCGGTCCCGGGTGGATTCTAAGACCCTGACCCGTAACACGAGGATCATTGCA GAGGCCCTGACTCGAGTCATCTACAACCTGACAGAGAAGGGGACACCCCCAGACATGCCGGTGTTCACAGAGCAGATGCAGATCCAGCAG GAGCAGCTGGACTCGGTGATGGACTGGCTCACCAACCAGCCGCGGGCCGCGCAGCTGGTGGACAAGGACAGCACCTTCCTCAGCACGCTG GAGCACCACCTGAGCCGCTACCTGAAGGACGTGAAGCAGCACCACGTCAAGGCTGACAAGCGGGACCCAGAGTTTGTCTTCTACGACCAG CTGAAGCAAGTGATGAATGCGTACAGAGTCAAGCCGGCCGTCTTTGACCTGCTCCTGGCTGTTGGCATTGCTGCCTACCTCGGCATGGCC TACGTGGCTGTCCAGCACTTCAGCCTCCTCTACAAGACCGTCCAGAGGCTGCTCGTGAAGGCCAAGACACAGTGACACAGCCACCCCCAC AGCCGGAGCCCCCGCCGCTCCACAGTCCCTGGGGCCGAGCACGAGTGAGTGGACACTGCCCCGCCGCGGGCGGCCCTGCAGGGACAGGGG CCCTCTCCCTCCCCGGCGGTGGTTGGAACACTGAATTACAGAGCTTTTTTCTGTTGCTCTCCGAGACTGGGGGGGGATTGTTTCTTCTTT TCCTTGTCTTTGAACTTCCTTGGAGGAGAGCTTGGGAGACGTCCCGGGGCCAGGCTACGGACTTGCGGACGAGCCCCCCAGTCCTGGGAG CCGGCCGCCCTCGGTCTGGTGTAAGCACACATGCACGATTAAAGAGGAGACGCCGGGACCCCCTGCCCGATCGCGCGCGGCCTCCGCCCA CCGCCTCCTGCCGCAAGGGGCCTGGACTGCAGGCCTGACCTGCTCCCTGCTCCGTGTCTGTCCTAGGACGTCCCCTCCCGCTCCCCGATG GTGGCGTGGACATGGTTATTTATCTCTGCTCCTTCTTGCCTGGAGGAGGGCAGTGCCAGCCCTGGGGTTCTGGGATTCCAGCCCTCCTGG AGCCTTTTGTTCCCCATGTGGTCTCAGTGACCCGTCCCCCTGACAGTGGGCTCGGGGAGCTGCATCACCCAGCCTTCCCCTTCTCCGACT GCAGGGTCTGATGTCATCATTGACAGCCTTTGCTTCGTGGGGGCCTGGCAGGGCCCCTGCCTCCCCGACCCCCGACCCACTGCAAATCCC CGTTCCCCTGCACTCCTCTTCTCCCAGCCCATCCCTCCGGCCCCTGTGCCTCTGCGGCCCCAGCCCAGCTCCCAGGGCCGTCACCTGCTT GGCCCTGGCCCAGCTCCCTGCCCTGAGTCCTGAGCCAGTGCCTGGTGTTTCCTGGGCTCGGTACTGGGCCCCCAGGCCATCCAGGCTTTG CCACGGCCAGTTGGTCCTCCCTGGGGAACTGGGTGCGGGTGGAGTACTGGGAGGCAGGAGGTGGCCCGGGGAGGCCTTGTGGCTCCTCCC CTCGCTCCTCGCCCTGGGCCTCAGCTTCCTCATCAATAGAAAGGATGTGTTCGGGGTGGGGGCGTCAGGTGAGAACGTTTGCTGGGAAGG AGAGGACTTGGGGCATGGCCTCTGGGGCCACCCTTCCTGGAACTCAGAGAGGAAGGTCCGGGCCCTCGGGAAGCCTTGGACAGAACCCTC CACCCCGCAGACCAGGCGTCGTGTGTGTGTGGGAGAGAAGGAGGCCCGTGTTGAGCTCAGGGAGACCCCGGTGTGTCCGTTCTTTAGCAA TATAACCTACCCAGTGCGTGCCGAGCAGGCTTGGTGGGGAAGGGACTTGAGCTGGGCAAGTCCTGGCCTGGCACCCGCAGCCGTCTCCCT TCCGTGGCCCAGGGAGGTGTTTGCTGTCCGAAGGACCTGGGCCGGCCCATGGGAGCCTGGGGTTCTGTCCAGATAGGACCAGGGGGTCTC ACTTTGGCCACCAGTTCTTCGGCCAGCACCTCTGCCCTCCAGAACCTGCAGCCTGGAGGGGTGAGGGGACAACCACCCCTCTTTCCTCCA GGTTGGCAGGGGACCCTCTTCTCCCGTCTGCCCTGCGGGTTGCCCGCCTCCTCCAGAGACTTGCCCAAGGGCCCATCACCACTGGCCTCT GGGCACTTGTGCTGAGACTCTGGGACCCAGGCAGCTGCCACCTTGTCACCATGAGAGAATTTGGGGAGTGCTTGCATGCTAGCCAGCAGG CTCCTGTCTGGGTGCCACGGGGCCAGCATTTTGGAGGGAGCTTCCTTCCTTCCTTCCTGGACAGGTCGTCATGATGGATGCACTGACTGA |
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FusionGenePPI for FZR1_NCLN |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| FZR1 | CDC27, SKIL, CDC14A, FBXO5, CDT1, MAD2L2, TPX2, ANAPC2, CDC20, CCNA2, IST1, CSF3R, SKP2, HSF2, SETD8, UBE2S, TK1, CDC6, CCNB1, GRIA1, EPHA4, TAS2R13, PIM1, CCNA1, CDK2, CDK5, E2F1, MAPK8, CDK1, RB1, ID1, NINL, SIX1, CLSPN, CDC25A, FOXM1, E2F3, MAK, RNF34, CKAP2, CKS1B, MOAP1, AURKB, USP37, PTTG1, GMNN, EMILIN1, DDB1, BRSK2, SPRTN, UBE2C, UBE2D1, UBE2D3, UBE2K, SMURF1, MDC1, ARHGAP32, DAXX, EYA1, BUB1B, ANAPC11, CDC14B, PTEN, VHL, SIRT2, CUEDC2, PHF8, CUL1, BTRC, PLK1, SOX2, HECW2, RACGAP1, STAU1, ANAPC4, TP53, ZC3HC1, CDR2, RBBP8, USP1, FANCD2, DCPS, DNM1L, ANAPC1, CDC26, ANAPC7, ANAPC5, CDC16, CDC23, ANAPC10, TACC3, TTK, NEDD9, TRIM33, NEK2, HCCS, CDCA3, LRRC46, RRM2, SENP2, FMR1, BEX1, BLID, CCL5, CYP17A1, DKK3, EPSTI1, MTA3, NAT2, PSMC3IP, THRSP, ANAPC15, PARK2, PRKDC, PAX3, KIAA0101, CCND1, PRR36, ANAPC13, CTGF, C16orf87, SRP68, CKS2, RRM2B, GLB1, HSPA2, HSP90AA1, CHEK2, CHEK1, WEE1, TRIM25, MCPH1, RNF157, CCNF, NUP98, HOXD13, LNP1, HHEX | NCLN | NOMO1, FBXO6, ILF3, KRTAP5-9, CCDC8, EGFR, DLK1, TNF, NTRK1, CANX, EPRS, SSR4, RPN2, TCTN3, TCTN1, XRCC3, SLC33A1, HUWE1, MCM2, FPR2, C1orf85, TMEM120A, TMEM120B, SERINC1, METTL9, AGPAT3, ARL15 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for FZR1_NCLN |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for FZR1_NCLN |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | FZR1 | C0032578 | Polyploidy | 1 | CTD_human |
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