FusionGDB Logo

Home

Download

Statistics

Examples

Help

Contact
Center for Computational Systems Medicine
leaf

FusionGeneSummary

leaf

FusionProtFeature

leaf

FusionGeneSequence

leaf

FusionGenePPI

leaf

RelatedDrugs

leaf

RelatedDiseases

Fusion gene ID: 13871

FusionGeneSummary for FRAS1_MRPL1

check button Fusion gene summary
Fusion gene informationFusion gene name: FRAS1_MRPL1
Fusion gene ID: 13871
HgeneTgene
Gene symbol

FRAS1

MRPL1

Gene ID

80144

65008

Gene nameFraser extracellular matrix complex subunit 1mitochondrial ribosomal protein L1
SynonymsFRASRS1BM022|L1MT|MRP-L1
Cytomap

4q21.21

4q21.1

Type of geneprotein-codingprotein-coding
Descriptionextracellular matrix protein FRAS1Fraser syndrome 139S ribosomal protein L1, mitochondrialmitochondrial large ribosomal subunit protein uL1m
Modification date2018051920180523
UniProtAcc

Q86XX4

Q9BYD6

Ensembl transtripts involved in fusion geneENST00000264899, ENST00000325942, 
ENST00000264895, 		ENST00000315567, 
ENST00000506674, 
Fusion gene scores* DoF score10 X 7 X 8=5604 X 3 X 4=48
# samples 105
** MAII scorelog2(10/560*10)=-2.48542682717024
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(5/48*10)=0.0588936890535686
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: FRAS1 [Title/Abstract] AND MRPL1 [Title/Abstract] AND fusion [Title/Abstract]

Functional or gene categories assigned by FusionGDB annotation
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check button Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
Data typeSourceCancer typeSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
TCGARVLUSCTCGA-66-2756-01AFRAS1chr4

78987170

+MRPL1chr4

78870951

+
TCGARVPRADTCGA-CH-5794-01AFRAS1chr4

78979239

+MRPL1chr4

78792898

+
* LD: Li Ding group's fusion gene list
  RV: Roel Verhaak group's fusion gene list
  ChiTaRs fusion database

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000264899ENST00000315567FRAS1chr4

78987170

+MRPL1chr4

78870951

+
5CDS-intronENST00000264899ENST00000506674FRAS1chr4

78987170

+MRPL1chr4

78870951

+
In-frameENST00000325942ENST00000315567FRAS1chr4

78987170

+MRPL1chr4

78870951

+
5CDS-intronENST00000325942ENST00000506674FRAS1chr4

78987170

+MRPL1chr4

78870951

+
In-frameENST00000264895ENST00000315567FRAS1chr4

78987170

+MRPL1chr4

78870951

+
5CDS-intronENST00000264895ENST00000506674FRAS1chr4

78987170

+MRPL1chr4

78870951

+
In-frameENST00000264899ENST00000315567FRAS1chr4

78979239

+MRPL1chr4

78792898

+
5CDS-intronENST00000264899ENST00000506674FRAS1chr4

78979239

+MRPL1chr4

78792898

+
In-frameENST00000325942ENST00000315567FRAS1chr4

78979239

+MRPL1chr4

78792898

+
5CDS-intronENST00000325942ENST00000506674FRAS1chr4

78979239

+MRPL1chr4

78792898

+
In-frameENST00000264895ENST00000315567FRAS1chr4

78979239

+MRPL1chr4

78792898

+
5CDS-intronENST00000264895ENST00000506674FRAS1chr4

78979239

+MRPL1chr4

78792898

+

Top

FusionProtFeatures for FRAS1_MRPL1


check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
FRAS1

Q86XX4

MRPL1

Q9BYD6


check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

.

* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- In-frame and not-retained protein feature among the 13 regional features.
>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneFRAS1chr4:78979239chr4:78792898ENST00000264895+174157_217254013DomainVWFC 3
HgeneFRAS1chr4:78979239chr4:78792898ENST00000264895+174219_279254013DomainVWFC 4
HgeneFRAS1chr4:78979239chr4:78792898ENST00000264895+1742543_2646254013DomainNote=Calx-beta 1
HgeneFRAS1chr4:78979239chr4:78792898ENST00000264895+1742659_2770254013DomainNote=Calx-beta 2
HgeneFRAS1chr4:78979239chr4:78792898ENST00000264895+1742784_2890254013DomainNote=Calx-beta 3
HgeneFRAS1chr4:78979239chr4:78792898ENST00000264895+17427_88254013DomainVWFC 1
HgeneFRAS1chr4:78979239chr4:78792898ENST00000264895+174283_343254013DomainVWFC 5
HgeneFRAS1chr4:78979239chr4:78792898ENST00000264895+1742905_3007254013DomainNote=Calx-beta 4
HgeneFRAS1chr4:78979239chr4:78792898ENST00000264895+1743025_3129254013DomainNote=Calx-beta 5
HgeneFRAS1chr4:78979239chr4:78792898ENST00000264895+174347_417254013DomainVWFC 6
HgeneFRAS1chr4:78979239chr4:78792898ENST00000264895+17493_153254013DomainVWFC 2
HgeneFRAS1chr4:78979239chr4:78792898ENST00000264899+119157_21725738DomainVWFC 3
HgeneFRAS1chr4:78979239chr4:78792898ENST00000264899+119219_27925738DomainVWFC 4
HgeneFRAS1chr4:78979239chr4:78792898ENST00000264899+1192543_264625738DomainNote=Calx-beta 1
HgeneFRAS1chr4:78979239chr4:78792898ENST00000264899+1192659_277025738DomainNote=Calx-beta 2
HgeneFRAS1chr4:78979239chr4:78792898ENST00000264899+1192784_289025738DomainNote=Calx-beta 3
HgeneFRAS1chr4:78979239chr4:78792898ENST00000264899+11927_8825738DomainVWFC 1
HgeneFRAS1chr4:78979239chr4:78792898ENST00000264899+119283_34325738DomainVWFC 5
HgeneFRAS1chr4:78979239chr4:78792898ENST00000264899+1192905_300725738DomainNote=Calx-beta 4
HgeneFRAS1chr4:78979239chr4:78792898ENST00000264899+1193025_312925738DomainNote=Calx-beta 5
HgeneFRAS1chr4:78979239chr4:78792898ENST00000264899+119347_41725738DomainVWFC 6
HgeneFRAS1chr4:78979239chr4:78792898ENST00000264899+11993_15325738DomainVWFC 2
HgeneFRAS1chr4:78979239chr4:78792898ENST00000325942+142157_217251977DomainVWFC 3
HgeneFRAS1chr4:78979239chr4:78792898ENST00000325942+142219_279251977DomainVWFC 4
HgeneFRAS1chr4:78979239chr4:78792898ENST00000325942+1422543_2646251977DomainNote=Calx-beta 1
HgeneFRAS1chr4:78979239chr4:78792898ENST00000325942+1422659_2770251977DomainNote=Calx-beta 2
HgeneFRAS1chr4:78979239chr4:78792898ENST00000325942+1422784_2890251977DomainNote=Calx-beta 3
HgeneFRAS1chr4:78979239chr4:78792898ENST00000325942+14227_88251977DomainVWFC 1
HgeneFRAS1chr4:78979239chr4:78792898ENST00000325942+142283_343251977DomainVWFC 5
HgeneFRAS1chr4:78979239chr4:78792898ENST00000325942+1422905_3007251977DomainNote=Calx-beta 4
HgeneFRAS1chr4:78979239chr4:78792898ENST00000325942+1423025_3129251977DomainNote=Calx-beta 5
HgeneFRAS1chr4:78979239chr4:78792898ENST00000325942+142347_417251977DomainVWFC 6
HgeneFRAS1chr4:78979239chr4:78792898ENST00000325942+14293_153251977DomainVWFC 2
HgeneFRAS1chr4:78987170chr4:78870951ENST00000264895+274157_217364013DomainVWFC 3
HgeneFRAS1chr4:78987170chr4:78870951ENST00000264895+274219_279364013DomainVWFC 4
HgeneFRAS1chr4:78987170chr4:78870951ENST00000264895+2742543_2646364013DomainNote=Calx-beta 1
HgeneFRAS1chr4:78987170chr4:78870951ENST00000264895+2742659_2770364013DomainNote=Calx-beta 2
HgeneFRAS1chr4:78987170chr4:78870951ENST00000264895+2742784_2890364013DomainNote=Calx-beta 3
HgeneFRAS1chr4:78987170chr4:78870951ENST00000264895+27427_88364013DomainVWFC 1
HgeneFRAS1chr4:78987170chr4:78870951ENST00000264895+274283_343364013DomainVWFC 5
HgeneFRAS1chr4:78987170chr4:78870951ENST00000264895+2742905_3007364013DomainNote=Calx-beta 4
HgeneFRAS1chr4:78987170chr4:78870951ENST00000264895+2743025_3129364013DomainNote=Calx-beta 5
HgeneFRAS1chr4:78987170chr4:78870951ENST00000264895+274347_417364013DomainVWFC 6
HgeneFRAS1chr4:78987170chr4:78870951ENST00000264895+27493_153364013DomainVWFC 2
HgeneFRAS1chr4:78987170chr4:78870951ENST00000264899+219157_21736738DomainVWFC 3
HgeneFRAS1chr4:78987170chr4:78870951ENST00000264899+219219_27936738DomainVWFC 4
HgeneFRAS1chr4:78987170chr4:78870951ENST00000264899+2192543_264636738DomainNote=Calx-beta 1
HgeneFRAS1chr4:78987170chr4:78870951ENST00000264899+2192659_277036738DomainNote=Calx-beta 2
HgeneFRAS1chr4:78987170chr4:78870951ENST00000264899+2192784_289036738DomainNote=Calx-beta 3
HgeneFRAS1chr4:78987170chr4:78870951ENST00000264899+21927_8836738DomainVWFC 1
HgeneFRAS1chr4:78987170chr4:78870951ENST00000264899+219283_34336738DomainVWFC 5
HgeneFRAS1chr4:78987170chr4:78870951ENST00000264899+2192905_300736738DomainNote=Calx-beta 4
HgeneFRAS1chr4:78987170chr4:78870951ENST00000264899+2193025_312936738DomainNote=Calx-beta 5
HgeneFRAS1chr4:78987170chr4:78870951ENST00000264899+219347_41736738DomainVWFC 6
HgeneFRAS1chr4:78987170chr4:78870951ENST00000264899+21993_15336738DomainVWFC 2
HgeneFRAS1chr4:78987170chr4:78870951ENST00000325942+242157_217361977DomainVWFC 3
HgeneFRAS1chr4:78987170chr4:78870951ENST00000325942+242219_279361977DomainVWFC 4
HgeneFRAS1chr4:78987170chr4:78870951ENST00000325942+2422543_2646361977DomainNote=Calx-beta 1
HgeneFRAS1chr4:78987170chr4:78870951ENST00000325942+2422659_2770361977DomainNote=Calx-beta 2
HgeneFRAS1chr4:78987170chr4:78870951ENST00000325942+2422784_2890361977DomainNote=Calx-beta 3
HgeneFRAS1chr4:78987170chr4:78870951ENST00000325942+24227_88361977DomainVWFC 1
HgeneFRAS1chr4:78987170chr4:78870951ENST00000325942+242283_343361977DomainVWFC 5
HgeneFRAS1chr4:78987170chr4:78870951ENST00000325942+2422905_3007361977DomainNote=Calx-beta 4
HgeneFRAS1chr4:78987170chr4:78870951ENST00000325942+2423025_3129361977DomainNote=Calx-beta 5
HgeneFRAS1chr4:78987170chr4:78870951ENST00000325942+242347_417361977DomainVWFC 6
HgeneFRAS1chr4:78987170chr4:78870951ENST00000325942+24293_153361977DomainVWFC 2
HgeneFRAS1chr4:78979239chr4:78792898ENST00000264895+1741046_1089254013RepeatNote=FU 14
HgeneFRAS1chr4:78979239chr4:78792898ENST00000264895+1741102_1197254013RepeatCSPG 1
HgeneFRAS1chr4:78979239chr4:78792898ENST00000264895+1741217_1308254013RepeatCSPG 2
HgeneFRAS1chr4:78979239chr4:78792898ENST00000264895+1741329_1438254013RepeatCSPG 3
HgeneFRAS1chr4:78979239chr4:78792898ENST00000264895+1741463_1559254013RepeatCSPG 4
HgeneFRAS1chr4:78979239chr4:78792898ENST00000264895+1741595_1689254013RepeatCSPG 5
HgeneFRAS1chr4:78979239chr4:78792898ENST00000264895+1741710_1810254013RepeatCSPG 6
HgeneFRAS1chr4:78979239chr4:78792898ENST00000264895+1741833_1936254013RepeatCSPG 7
HgeneFRAS1chr4:78979239chr4:78792898ENST00000264895+1741957_2057254013RepeatCSPG 8
HgeneFRAS1chr4:78979239chr4:78792898ENST00000264895+1742078_2177254013RepeatCSPG 9
HgeneFRAS1chr4:78979239chr4:78792898ENST00000264895+1742199_2291254013RepeatCSPG 10
HgeneFRAS1chr4:78979239chr4:78792898ENST00000264895+1742311_2404254013RepeatCSPG 11
HgeneFRAS1chr4:78979239chr4:78792898ENST00000264895+1742439_2536254013RepeatCSPG 12
HgeneFRAS1chr4:78979239chr4:78792898ENST00000264895+174409_460254013RepeatNote=FU 1
HgeneFRAS1chr4:78979239chr4:78792898ENST00000264895+174462_505254013RepeatNote=FU 2
HgeneFRAS1chr4:78979239chr4:78792898ENST00000264895+174507_553254013RepeatNote=FU 3
HgeneFRAS1chr4:78979239chr4:78792898ENST00000264895+174555_599254013RepeatNote=FU 4
HgeneFRAS1chr4:78979239chr4:78792898ENST00000264895+174602_647254013RepeatNote=FU 5
HgeneFRAS1chr4:78979239chr4:78792898ENST00000264895+174649_705254013RepeatNote=FU 6
HgeneFRAS1chr4:78979239chr4:78792898ENST00000264895+174708_753254013RepeatNote=FU 7
HgeneFRAS1chr4:78979239chr4:78792898ENST00000264895+174755_800254013RepeatNote=FU 8
HgeneFRAS1chr4:78979239chr4:78792898ENST00000264895+174803_852254013RepeatNote=FU 9
HgeneFRAS1chr4:78979239chr4:78792898ENST00000264895+174854_900254013RepeatNote=FU 10
HgeneFRAS1chr4:78979239chr4:78792898ENST00000264895+174903_948254013RepeatNote=FU 11
HgeneFRAS1chr4:78979239chr4:78792898ENST00000264895+174952_997254013RepeatNote=FU 12
HgeneFRAS1chr4:78979239chr4:78792898ENST00000264895+174999_1042254013RepeatNote=FU 13
HgeneFRAS1chr4:78979239chr4:78792898ENST00000264899+1191046_108925738RepeatNote=FU 14
HgeneFRAS1chr4:78979239chr4:78792898ENST00000264899+1191102_119725738RepeatCSPG 1
HgeneFRAS1chr4:78979239chr4:78792898ENST00000264899+1191217_130825738RepeatCSPG 2
HgeneFRAS1chr4:78979239chr4:78792898ENST00000264899+1191329_143825738RepeatCSPG 3
HgeneFRAS1chr4:78979239chr4:78792898ENST00000264899+1191463_155925738RepeatCSPG 4
HgeneFRAS1chr4:78979239chr4:78792898ENST00000264899+1191595_168925738RepeatCSPG 5
HgeneFRAS1chr4:78979239chr4:78792898ENST00000264899+1191710_181025738RepeatCSPG 6
HgeneFRAS1chr4:78979239chr4:78792898ENST00000264899+1191833_193625738RepeatCSPG 7
HgeneFRAS1chr4:78979239chr4:78792898ENST00000264899+1191957_205725738RepeatCSPG 8
HgeneFRAS1chr4:78979239chr4:78792898ENST00000264899+1192078_217725738RepeatCSPG 9
HgeneFRAS1chr4:78979239chr4:78792898ENST00000264899+1192199_229125738RepeatCSPG 10
HgeneFRAS1chr4:78979239chr4:78792898ENST00000264899+1192311_240425738RepeatCSPG 11
HgeneFRAS1chr4:78979239chr4:78792898ENST00000264899+1192439_253625738RepeatCSPG 12
HgeneFRAS1chr4:78979239chr4:78792898ENST00000264899+119409_46025738RepeatNote=FU 1
HgeneFRAS1chr4:78979239chr4:78792898ENST00000264899+119462_50525738RepeatNote=FU 2
HgeneFRAS1chr4:78979239chr4:78792898ENST00000264899+119507_55325738RepeatNote=FU 3
HgeneFRAS1chr4:78979239chr4:78792898ENST00000264899+119555_59925738RepeatNote=FU 4
HgeneFRAS1chr4:78979239chr4:78792898ENST00000264899+119602_64725738RepeatNote=FU 5
HgeneFRAS1chr4:78979239chr4:78792898ENST00000264899+119649_70525738RepeatNote=FU 6
HgeneFRAS1chr4:78979239chr4:78792898ENST00000264899+119708_75325738RepeatNote=FU 7
HgeneFRAS1chr4:78979239chr4:78792898ENST00000264899+119755_80025738RepeatNote=FU 8
HgeneFRAS1chr4:78979239chr4:78792898ENST00000264899+119803_85225738RepeatNote=FU 9
HgeneFRAS1chr4:78979239chr4:78792898ENST00000264899+119854_90025738RepeatNote=FU 10
HgeneFRAS1chr4:78979239chr4:78792898ENST00000264899+119903_94825738RepeatNote=FU 11
HgeneFRAS1chr4:78979239chr4:78792898ENST00000264899+119952_99725738RepeatNote=FU 12
HgeneFRAS1chr4:78979239chr4:78792898ENST00000264899+119999_104225738RepeatNote=FU 13
HgeneFRAS1chr4:78979239chr4:78792898ENST00000325942+1421046_1089251977RepeatNote=FU 14
HgeneFRAS1chr4:78979239chr4:78792898ENST00000325942+1421102_1197251977RepeatCSPG 1
HgeneFRAS1chr4:78979239chr4:78792898ENST00000325942+1421217_1308251977RepeatCSPG 2
HgeneFRAS1chr4:78979239chr4:78792898ENST00000325942+1421329_1438251977RepeatCSPG 3
HgeneFRAS1chr4:78979239chr4:78792898ENST00000325942+1421463_1559251977RepeatCSPG 4
HgeneFRAS1chr4:78979239chr4:78792898ENST00000325942+1421595_1689251977RepeatCSPG 5
HgeneFRAS1chr4:78979239chr4:78792898ENST00000325942+1421710_1810251977RepeatCSPG 6
HgeneFRAS1chr4:78979239chr4:78792898ENST00000325942+1421833_1936251977RepeatCSPG 7
HgeneFRAS1chr4:78979239chr4:78792898ENST00000325942+1421957_2057251977RepeatCSPG 8
HgeneFRAS1chr4:78979239chr4:78792898ENST00000325942+1422078_2177251977RepeatCSPG 9
HgeneFRAS1chr4:78979239chr4:78792898ENST00000325942+1422199_2291251977RepeatCSPG 10
HgeneFRAS1chr4:78979239chr4:78792898ENST00000325942+1422311_2404251977RepeatCSPG 11
HgeneFRAS1chr4:78979239chr4:78792898ENST00000325942+1422439_2536251977RepeatCSPG 12
HgeneFRAS1chr4:78979239chr4:78792898ENST00000325942+142409_460251977RepeatNote=FU 1
HgeneFRAS1chr4:78979239chr4:78792898ENST00000325942+142462_505251977RepeatNote=FU 2
HgeneFRAS1chr4:78979239chr4:78792898ENST00000325942+142507_553251977RepeatNote=FU 3
HgeneFRAS1chr4:78979239chr4:78792898ENST00000325942+142555_599251977RepeatNote=FU 4
HgeneFRAS1chr4:78979239chr4:78792898ENST00000325942+142602_647251977RepeatNote=FU 5
HgeneFRAS1chr4:78979239chr4:78792898ENST00000325942+142649_705251977RepeatNote=FU 6
HgeneFRAS1chr4:78979239chr4:78792898ENST00000325942+142708_753251977RepeatNote=FU 7
HgeneFRAS1chr4:78979239chr4:78792898ENST00000325942+142755_800251977RepeatNote=FU 8
HgeneFRAS1chr4:78979239chr4:78792898ENST00000325942+142803_852251977RepeatNote=FU 9
HgeneFRAS1chr4:78979239chr4:78792898ENST00000325942+142854_900251977RepeatNote=FU 10
HgeneFRAS1chr4:78979239chr4:78792898ENST00000325942+142903_948251977RepeatNote=FU 11
HgeneFRAS1chr4:78979239chr4:78792898ENST00000325942+142952_997251977RepeatNote=FU 12
HgeneFRAS1chr4:78979239chr4:78792898ENST00000325942+142999_1042251977RepeatNote=FU 13
HgeneFRAS1chr4:78987170chr4:78870951ENST00000264895+2741046_1089364013RepeatNote=FU 14
HgeneFRAS1chr4:78987170chr4:78870951ENST00000264895+2741102_1197364013RepeatCSPG 1
HgeneFRAS1chr4:78987170chr4:78870951ENST00000264895+2741217_1308364013RepeatCSPG 2
HgeneFRAS1chr4:78987170chr4:78870951ENST00000264895+2741329_1438364013RepeatCSPG 3
HgeneFRAS1chr4:78987170chr4:78870951ENST00000264895+2741463_1559364013RepeatCSPG 4
HgeneFRAS1chr4:78987170chr4:78870951ENST00000264895+2741595_1689364013RepeatCSPG 5
HgeneFRAS1chr4:78987170chr4:78870951ENST00000264895+2741710_1810364013RepeatCSPG 6
HgeneFRAS1chr4:78987170chr4:78870951ENST00000264895+2741833_1936364013RepeatCSPG 7
HgeneFRAS1chr4:78987170chr4:78870951ENST00000264895+2741957_2057364013RepeatCSPG 8
HgeneFRAS1chr4:78987170chr4:78870951ENST00000264895+2742078_2177364013RepeatCSPG 9
HgeneFRAS1chr4:78987170chr4:78870951ENST00000264895+2742199_2291364013RepeatCSPG 10
HgeneFRAS1chr4:78987170chr4:78870951ENST00000264895+2742311_2404364013RepeatCSPG 11
HgeneFRAS1chr4:78987170chr4:78870951ENST00000264895+2742439_2536364013RepeatCSPG 12
HgeneFRAS1chr4:78987170chr4:78870951ENST00000264895+274409_460364013RepeatNote=FU 1
HgeneFRAS1chr4:78987170chr4:78870951ENST00000264895+274462_505364013RepeatNote=FU 2
HgeneFRAS1chr4:78987170chr4:78870951ENST00000264895+274507_553364013RepeatNote=FU 3
HgeneFRAS1chr4:78987170chr4:78870951ENST00000264895+274555_599364013RepeatNote=FU 4
HgeneFRAS1chr4:78987170chr4:78870951ENST00000264895+274602_647364013RepeatNote=FU 5
HgeneFRAS1chr4:78987170chr4:78870951ENST00000264895+274649_705364013RepeatNote=FU 6
HgeneFRAS1chr4:78987170chr4:78870951ENST00000264895+274708_753364013RepeatNote=FU 7
HgeneFRAS1chr4:78987170chr4:78870951ENST00000264895+274755_800364013RepeatNote=FU 8
HgeneFRAS1chr4:78987170chr4:78870951ENST00000264895+274803_852364013RepeatNote=FU 9
HgeneFRAS1chr4:78987170chr4:78870951ENST00000264895+274854_900364013RepeatNote=FU 10
HgeneFRAS1chr4:78987170chr4:78870951ENST00000264895+274903_948364013RepeatNote=FU 11
HgeneFRAS1chr4:78987170chr4:78870951ENST00000264895+274952_997364013RepeatNote=FU 12
HgeneFRAS1chr4:78987170chr4:78870951ENST00000264895+274999_1042364013RepeatNote=FU 13
HgeneFRAS1chr4:78987170chr4:78870951ENST00000264899+2191046_108936738RepeatNote=FU 14
HgeneFRAS1chr4:78987170chr4:78870951ENST00000264899+2191102_119736738RepeatCSPG 1
HgeneFRAS1chr4:78987170chr4:78870951ENST00000264899+2191217_130836738RepeatCSPG 2
HgeneFRAS1chr4:78987170chr4:78870951ENST00000264899+2191329_143836738RepeatCSPG 3
HgeneFRAS1chr4:78987170chr4:78870951ENST00000264899+2191463_155936738RepeatCSPG 4
HgeneFRAS1chr4:78987170chr4:78870951ENST00000264899+2191595_168936738RepeatCSPG 5
HgeneFRAS1chr4:78987170chr4:78870951ENST00000264899+2191710_181036738RepeatCSPG 6
HgeneFRAS1chr4:78987170chr4:78870951ENST00000264899+2191833_193636738RepeatCSPG 7
HgeneFRAS1chr4:78987170chr4:78870951ENST00000264899+2191957_205736738RepeatCSPG 8
HgeneFRAS1chr4:78987170chr4:78870951ENST00000264899+2192078_217736738RepeatCSPG 9
HgeneFRAS1chr4:78987170chr4:78870951ENST00000264899+2192199_229136738RepeatCSPG 10
HgeneFRAS1chr4:78987170chr4:78870951ENST00000264899+2192311_240436738RepeatCSPG 11
HgeneFRAS1chr4:78987170chr4:78870951ENST00000264899+2192439_253636738RepeatCSPG 12
HgeneFRAS1chr4:78987170chr4:78870951ENST00000264899+219409_46036738RepeatNote=FU 1
HgeneFRAS1chr4:78987170chr4:78870951ENST00000264899+219462_50536738RepeatNote=FU 2
HgeneFRAS1chr4:78987170chr4:78870951ENST00000264899+219507_55336738RepeatNote=FU 3
HgeneFRAS1chr4:78987170chr4:78870951ENST00000264899+219555_59936738RepeatNote=FU 4
HgeneFRAS1chr4:78987170chr4:78870951ENST00000264899+219602_64736738RepeatNote=FU 5
HgeneFRAS1chr4:78987170chr4:78870951ENST00000264899+219649_70536738RepeatNote=FU 6
HgeneFRAS1chr4:78987170chr4:78870951ENST00000264899+219708_75336738RepeatNote=FU 7
HgeneFRAS1chr4:78987170chr4:78870951ENST00000264899+219755_80036738RepeatNote=FU 8
HgeneFRAS1chr4:78987170chr4:78870951ENST00000264899+219803_85236738RepeatNote=FU 9
HgeneFRAS1chr4:78987170chr4:78870951ENST00000264899+219854_90036738RepeatNote=FU 10
HgeneFRAS1chr4:78987170chr4:78870951ENST00000264899+219903_94836738RepeatNote=FU 11
HgeneFRAS1chr4:78987170chr4:78870951ENST00000264899+219952_99736738RepeatNote=FU 12
HgeneFRAS1chr4:78987170chr4:78870951ENST00000264899+219999_104236738RepeatNote=FU 13
HgeneFRAS1chr4:78987170chr4:78870951ENST00000325942+2421046_1089361977RepeatNote=FU 14
HgeneFRAS1chr4:78987170chr4:78870951ENST00000325942+2421102_1197361977RepeatCSPG 1
HgeneFRAS1chr4:78987170chr4:78870951ENST00000325942+2421217_1308361977RepeatCSPG 2
HgeneFRAS1chr4:78987170chr4:78870951ENST00000325942+2421329_1438361977RepeatCSPG 3
HgeneFRAS1chr4:78987170chr4:78870951ENST00000325942+2421463_1559361977RepeatCSPG 4
HgeneFRAS1chr4:78987170chr4:78870951ENST00000325942+2421595_1689361977RepeatCSPG 5
HgeneFRAS1chr4:78987170chr4:78870951ENST00000325942+2421710_1810361977RepeatCSPG 6
HgeneFRAS1chr4:78987170chr4:78870951ENST00000325942+2421833_1936361977RepeatCSPG 7
HgeneFRAS1chr4:78987170chr4:78870951ENST00000325942+2421957_2057361977RepeatCSPG 8
HgeneFRAS1chr4:78987170chr4:78870951ENST00000325942+2422078_2177361977RepeatCSPG 9
HgeneFRAS1chr4:78987170chr4:78870951ENST00000325942+2422199_2291361977RepeatCSPG 10
HgeneFRAS1chr4:78987170chr4:78870951ENST00000325942+2422311_2404361977RepeatCSPG 11
HgeneFRAS1chr4:78987170chr4:78870951ENST00000325942+2422439_2536361977RepeatCSPG 12
HgeneFRAS1chr4:78987170chr4:78870951ENST00000325942+242409_460361977RepeatNote=FU 1
HgeneFRAS1chr4:78987170chr4:78870951ENST00000325942+242462_505361977RepeatNote=FU 2
HgeneFRAS1chr4:78987170chr4:78870951ENST00000325942+242507_553361977RepeatNote=FU 3
HgeneFRAS1chr4:78987170chr4:78870951ENST00000325942+242555_599361977RepeatNote=FU 4
HgeneFRAS1chr4:78987170chr4:78870951ENST00000325942+242602_647361977RepeatNote=FU 5
HgeneFRAS1chr4:78987170chr4:78870951ENST00000325942+242649_705361977RepeatNote=FU 6
HgeneFRAS1chr4:78987170chr4:78870951ENST00000325942+242708_753361977RepeatNote=FU 7
HgeneFRAS1chr4:78987170chr4:78870951ENST00000325942+242755_800361977RepeatNote=FU 8
HgeneFRAS1chr4:78987170chr4:78870951ENST00000325942+242803_852361977RepeatNote=FU 9
HgeneFRAS1chr4:78987170chr4:78870951ENST00000325942+242854_900361977RepeatNote=FU 10
HgeneFRAS1chr4:78987170chr4:78870951ENST00000325942+242903_948361977RepeatNote=FU 11
HgeneFRAS1chr4:78987170chr4:78870951ENST00000325942+242952_997361977RepeatNote=FU 12
HgeneFRAS1chr4:78987170chr4:78870951ENST00000325942+242999_1042361977RepeatNote=FU 13
HgeneFRAS1chr4:78979239chr4:78792898ENST00000264895+17427_3901254013Topological domainExtracellular
HgeneFRAS1chr4:78979239chr4:78792898ENST00000264895+1743923_4008254013Topological domainCytoplasmic
HgeneFRAS1chr4:78979239chr4:78792898ENST00000264899+11927_390125738Topological domainExtracellular
HgeneFRAS1chr4:78979239chr4:78792898ENST00000264899+1193923_400825738Topological domainCytoplasmic
HgeneFRAS1chr4:78979239chr4:78792898ENST00000325942+14227_3901251977Topological domainExtracellular
HgeneFRAS1chr4:78979239chr4:78792898ENST00000325942+1423923_4008251977Topological domainCytoplasmic
HgeneFRAS1chr4:78987170chr4:78870951ENST00000264895+27427_3901364013Topological domainExtracellular
HgeneFRAS1chr4:78987170chr4:78870951ENST00000264895+2743923_4008364013Topological domainCytoplasmic
HgeneFRAS1chr4:78987170chr4:78870951ENST00000264899+21927_390136738Topological domainExtracellular
HgeneFRAS1chr4:78987170chr4:78870951ENST00000264899+2193923_400836738Topological domainCytoplasmic
HgeneFRAS1chr4:78987170chr4:78870951ENST00000325942+24227_3901361977Topological domainExtracellular
HgeneFRAS1chr4:78987170chr4:78870951ENST00000325942+2423923_4008361977Topological domainCytoplasmic
HgeneFRAS1chr4:78979239chr4:78792898ENST00000264895+1743902_3922254013TransmembraneHelical
HgeneFRAS1chr4:78979239chr4:78792898ENST00000264899+1193902_392225738TransmembraneHelical
HgeneFRAS1chr4:78979239chr4:78792898ENST00000325942+1423902_3922251977TransmembraneHelical
HgeneFRAS1chr4:78987170chr4:78870951ENST00000264895+2743902_3922364013TransmembraneHelical
HgeneFRAS1chr4:78987170chr4:78870951ENST00000264899+2193902_392236738TransmembraneHelical
HgeneFRAS1chr4:78987170chr4:78870951ENST00000325942+2423902_3922361977TransmembraneHelical


Top

FusionGeneSequence for FRAS1_MRPL1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.
>In-frame_FRAS1_ENST00000264899_chr4_78987170_+_MRPL1_ENST00000315567_chr4_78870951_+_103aa
MGVLKVWLGLALALAEFAVLPHHSEGACVYQDSLLALDMSSDQIAANLQAVINEVCRHRPLNLGPFVVRAFLRSSTSEGLLLKIDPLLPK

>In-frame_FRAS1_ENST00000325942_chr4_78987170_+_MRPL1_ENST00000315567_chr4_78870951_+_103aa
MGVLKVWLGLALALAEFAVLPHHSEGACVYQDSLLALDMSSDQIAANLQAVINEVCRHRPLNLGPFVVRAFLRSSTSEGLLLKIDPLLPK

>In-frame_FRAS1_ENST00000264895_chr4_78987170_+_MRPL1_ENST00000315567_chr4_78870951_+_103aa
MGVLKVWLGLALALAEFAVLPHHSEGACVYQDSLLALDMSSDQIAANLQAVINEVCRHRPLNLGPFVVRAFLRSSTSEGLLLKIDPLLPK

>In-frame_FRAS1_ENST00000264899_chr4_78979239_+_MRPL1_ENST00000315567_chr4_78792898_+_341aa
MGVLKVWLGLALALAEFAVLPHHSEALIHHQRHSLSKMVYQTSLCSCSVNIRVPNRHFAAATKSAKKTKKGAKEKTPDEKKDEIEKIKAY
PYMEGEPEDDVYLKRLYPRQIYEVEKAVHLLKKFQILDFTSPKQSVYLDLTLDMALGKKKNVEPFTSVLSLPYPFASEINKVAVFTENAS
EVKIAEENGAAFAGGTSLIQKIWDDEIVADFYVAVPEIMPELNRLRKKLNKKYPKLSRNSIGRDIPKMLELFKNGHEIKVDEERENFLQT

>In-frame_FRAS1_ENST00000325942_chr4_78979239_+_MRPL1_ENST00000315567_chr4_78792898_+_341aa
MGVLKVWLGLALALAEFAVLPHHSEALIHHQRHSLSKMVYQTSLCSCSVNIRVPNRHFAAATKSAKKTKKGAKEKTPDEKKDEIEKIKAY
PYMEGEPEDDVYLKRLYPRQIYEVEKAVHLLKKFQILDFTSPKQSVYLDLTLDMALGKKKNVEPFTSVLSLPYPFASEINKVAVFTENAS
EVKIAEENGAAFAGGTSLIQKIWDDEIVADFYVAVPEIMPELNRLRKKLNKKYPKLSRNSIGRDIPKMLELFKNGHEIKVDEERENFLQT

>In-frame_FRAS1_ENST00000264895_chr4_78979239_+_MRPL1_ENST00000315567_chr4_78792898_+_341aa
MGVLKVWLGLALALAEFAVLPHHSEALIHHQRHSLSKMVYQTSLCSCSVNIRVPNRHFAAATKSAKKTKKGAKEKTPDEKKDEIEKIKAY
PYMEGEPEDDVYLKRLYPRQIYEVEKAVHLLKKFQILDFTSPKQSVYLDLTLDMALGKKKNVEPFTSVLSLPYPFASEINKVAVFTENAS
EVKIAEENGAAFAGGTSLIQKIWDDEIVADFYVAVPEIMPELNRLRKKLNKKYPKLSRNSIGRDIPKMLELFKNGHEIKVDEERENFLQT


* Fusion transcript sequences (only coding sequence (CDS) region).
>In-frame_FRAS1_ENST00000264899_chr4_78987170_+_MRPL1_ENST00000315567_chr4_78870951_+_309nt
ATGGGTGTCCTCAAAGTGTGGCTCGGGCTGGCCCTAGCGTTGGCGGAATTTGCAGTATTGCCTCATCATTCCGAAGGTGCTTGTGTCTAT
CAGGATTCCTTGTTGGCGTTGGATATGTCAAGTGACCAGATAGCTGCCAATCTGCAAGCAGTTATTAATGAAGTTTGTAGGCACAGACCG
CTGAATTTGGGTCCCTTTGTGGTACGTGCTTTCCTTCGTAGTTCAACAAGTGAAGGTTTATTACTGAAGATTGATCCATTGTTGCCTAAA

>In-frame_FRAS1_ENST00000325942_chr4_78987170_+_MRPL1_ENST00000315567_chr4_78870951_+_309nt
ATGGGTGTCCTCAAAGTGTGGCTCGGGCTGGCCCTAGCGTTGGCGGAATTTGCAGTATTGCCTCATCATTCCGAAGGTGCTTGTGTCTAT
CAGGATTCCTTGTTGGCGTTGGATATGTCAAGTGACCAGATAGCTGCCAATCTGCAAGCAGTTATTAATGAAGTTTGTAGGCACAGACCG
CTGAATTTGGGTCCCTTTGTGGTACGTGCTTTCCTTCGTAGTTCAACAAGTGAAGGTTTATTACTGAAGATTGATCCATTGTTGCCTAAA

>In-frame_FRAS1_ENST00000264895_chr4_78987170_+_MRPL1_ENST00000315567_chr4_78870951_+_309nt
ATGGGTGTCCTCAAAGTGTGGCTCGGGCTGGCCCTAGCGTTGGCGGAATTTGCAGTATTGCCTCATCATTCCGAAGGTGCTTGTGTCTAT
CAGGATTCCTTGTTGGCGTTGGATATGTCAAGTGACCAGATAGCTGCCAATCTGCAAGCAGTTATTAATGAAGTTTGTAGGCACAGACCG
CTGAATTTGGGTCCCTTTGTGGTACGTGCTTTCCTTCGTAGTTCAACAAGTGAAGGTTTATTACTGAAGATTGATCCATTGTTGCCTAAA

>In-frame_FRAS1_ENST00000264899_chr4_78979239_+_MRPL1_ENST00000315567_chr4_78792898_+_1023nt
ATGGGTGTCCTCAAAGTGTGGCTCGGGCTGGCCCTAGCGTTGGCGGAATTTGCAGTATTGCCTCATCATTCCGAAGCCTTGATACATCAT
CAAAGGCATAGCCTTTCCAAGATGGTTTATCAGACATCACTTTGTTCTTGTTCTGTAAACATCCGAGTGCCCAACAGACATTTTGCTGCT
GCTACAAAGTCTGCAAAGAAAACAAAAAAAGGTGCTAAAGAAAAAACACCAGATGAGAAAAAAGATGAAATAGAAAAAATAAAAGCATAT
CCCTATATGGAAGGCGAACCTGAGGATGATGTCTATTTAAAACGCTTATACCCGAGACAGATATATGAGGTGGAGAAAGCTGTTCACTTA
CTTAAGAAATTTCAAATTCTTGACTTTACTAGTCCAAAGCAAAGTGTTTATCTTGATTTGACACTGGATATGGCACTGGGAAAGAAGAAA
AACGTGGAGCCATTTACCAGTGTTCTTAGTTTGCCATACCCATTTGCTTCCGAAATCAATAAAGTTGCTGTATTTACAGAGAATGCATCA
GAGGTCAAAATAGCGGAAGAAAATGGAGCTGCATTTGCAGGAGGCACTAGTCTGATACAGAAGATTTGGGATGATGAAATTGTTGCAGAC
TTTTACGTAGCTGTTCCAGAAATAATGCCTGAACTTAATCGATTAAGGAAGAAACTGAATAAAAAATATCCAAAGCTTTCTCGAAATTCC
ATTGGCCGTGACATCCCCAAAATGCTTGAATTATTTAAAAATGGACATGAAATTAAGGTAGATGAAGAAAGGGAGAACTTTCTCCAGACC
AAAATAGCAACATTGGATATGTCAAGTGACCAGATAGCTGCCAATCTGCAAGCAGTTATTAATGAAGTTTGTAGGCACAGACCGCTGAAT
TTGGGTCCCTTTGTGGTACGTGCTTTCCTTCGTAGTTCAACAAGTGAAGGTTTATTACTGAAGATTGATCCATTGTTGCCTAAAGAAGTA

>In-frame_FRAS1_ENST00000325942_chr4_78979239_+_MRPL1_ENST00000315567_chr4_78792898_+_1023nt
ATGGGTGTCCTCAAAGTGTGGCTCGGGCTGGCCCTAGCGTTGGCGGAATTTGCAGTATTGCCTCATCATTCCGAAGCCTTGATACATCAT
CAAAGGCATAGCCTTTCCAAGATGGTTTATCAGACATCACTTTGTTCTTGTTCTGTAAACATCCGAGTGCCCAACAGACATTTTGCTGCT
GCTACAAAGTCTGCAAAGAAAACAAAAAAAGGTGCTAAAGAAAAAACACCAGATGAGAAAAAAGATGAAATAGAAAAAATAAAAGCATAT
CCCTATATGGAAGGCGAACCTGAGGATGATGTCTATTTAAAACGCTTATACCCGAGACAGATATATGAGGTGGAGAAAGCTGTTCACTTA
CTTAAGAAATTTCAAATTCTTGACTTTACTAGTCCAAAGCAAAGTGTTTATCTTGATTTGACACTGGATATGGCACTGGGAAAGAAGAAA
AACGTGGAGCCATTTACCAGTGTTCTTAGTTTGCCATACCCATTTGCTTCCGAAATCAATAAAGTTGCTGTATTTACAGAGAATGCATCA
GAGGTCAAAATAGCGGAAGAAAATGGAGCTGCATTTGCAGGAGGCACTAGTCTGATACAGAAGATTTGGGATGATGAAATTGTTGCAGAC
TTTTACGTAGCTGTTCCAGAAATAATGCCTGAACTTAATCGATTAAGGAAGAAACTGAATAAAAAATATCCAAAGCTTTCTCGAAATTCC
ATTGGCCGTGACATCCCCAAAATGCTTGAATTATTTAAAAATGGACATGAAATTAAGGTAGATGAAGAAAGGGAGAACTTTCTCCAGACC
AAAATAGCAACATTGGATATGTCAAGTGACCAGATAGCTGCCAATCTGCAAGCAGTTATTAATGAAGTTTGTAGGCACAGACCGCTGAAT
TTGGGTCCCTTTGTGGTACGTGCTTTCCTTCGTAGTTCAACAAGTGAAGGTTTATTACTGAAGATTGATCCATTGTTGCCTAAAGAAGTA

>In-frame_FRAS1_ENST00000264895_chr4_78979239_+_MRPL1_ENST00000315567_chr4_78792898_+_1023nt
ATGGGTGTCCTCAAAGTGTGGCTCGGGCTGGCCCTAGCGTTGGCGGAATTTGCAGTATTGCCTCATCATTCCGAAGCCTTGATACATCAT
CAAAGGCATAGCCTTTCCAAGATGGTTTATCAGACATCACTTTGTTCTTGTTCTGTAAACATCCGAGTGCCCAACAGACATTTTGCTGCT
GCTACAAAGTCTGCAAAGAAAACAAAAAAAGGTGCTAAAGAAAAAACACCAGATGAGAAAAAAGATGAAATAGAAAAAATAAAAGCATAT
CCCTATATGGAAGGCGAACCTGAGGATGATGTCTATTTAAAACGCTTATACCCGAGACAGATATATGAGGTGGAGAAAGCTGTTCACTTA
CTTAAGAAATTTCAAATTCTTGACTTTACTAGTCCAAAGCAAAGTGTTTATCTTGATTTGACACTGGATATGGCACTGGGAAAGAAGAAA
AACGTGGAGCCATTTACCAGTGTTCTTAGTTTGCCATACCCATTTGCTTCCGAAATCAATAAAGTTGCTGTATTTACAGAGAATGCATCA
GAGGTCAAAATAGCGGAAGAAAATGGAGCTGCATTTGCAGGAGGCACTAGTCTGATACAGAAGATTTGGGATGATGAAATTGTTGCAGAC
TTTTACGTAGCTGTTCCAGAAATAATGCCTGAACTTAATCGATTAAGGAAGAAACTGAATAAAAAATATCCAAAGCTTTCTCGAAATTCC
ATTGGCCGTGACATCCCCAAAATGCTTGAATTATTTAAAAATGGACATGAAATTAAGGTAGATGAAGAAAGGGAGAACTTTCTCCAGACC
AAAATAGCAACATTGGATATGTCAAGTGACCAGATAGCTGCCAATCTGCAAGCAGTTATTAATGAAGTTTGTAGGCACAGACCGCTGAAT
TTGGGTCCCTTTGTGGTACGTGCTTTCCTTCGTAGTTCAACAAGTGAAGGTTTATTACTGAAGATTGATCCATTGTTGCCTAAAGAAGTA


* Fusion transcript sequences (Full-length transcript).
>In-frame_FRAS1_ENST00000264899_chr4_78987170_+_MRPL1_ENST00000315567_chr4_78870951_+_932nt
AACTTTAAAAAGCTGCTTCGGACAAACCAGAGCCAGGATTTCCACTGTCGGGGACCCGGGATCGGAAGGGTCTAGCCCGAGGGAAATGCT
GGAAGATCCCATCGGCCAGTGACCAGCAACTTTCCGGCGAGATTTTGACGCGGAGAACTGTGCTCTGCCTCCTCTTATTCTCCCAAAGCT
CACGTTGGCGTCCTGCCTTGCGGGGGAACTCGGCGCGCTCTCTGCCTGAGCAGCGAGTGAATTGAACCCCAGCCCGCTCCGGCGCCTCCG
GGCTGATGAGTGTCGCTCTCCGCCCGTCCATCTCTTTTTCCCGGAGGTAAAGGCCCGCGGTCCCCCACCTTCAGTGCGCCCGGGTTCCAA
GCGCCGGAGCCAGCGTTTTGGCGGAGCCGCTTCTTGGATGCTGAAGGCTGGGCTCCTCCATCGTGGGTGCCGAGGCGGCGATGGGTGTCC
TCAAAGTGTGGCTCGGGCTGGCCCTAGCGTTGGCGGAATTTGCAGTATTGCCTCATCATTCCGAAGGTGCTTGTGTCTATCAGGATTCCT
TGTTGGCGTTGGATATGTCAAGTGACCAGATAGCTGCCAATCTGCAAGCAGTTATTAATGAAGTTTGTAGGCACAGACCGCTGAATTTGG
GTCCCTTTGTGGTACGTGCTTTCCTTCGTAGTTCAACAAGTGAAGGTTTATTACTGAAGATTGATCCATTGTTGCCTAAAGAAGTAAAAA
ATGAAGAAAGTGAAAAAGAAGATGCCTAAATGTGGTGAATTGTGAAATTACTTTCAGTGGTTTAAGAAGCAATGGAGAAAATGATAATAC
AGCATAATTTTTACATTTGATGTCTTGTTATTGATCATACTTGAAAGTGAACTTTAACATTGAAAAATCGTACAGTCATTTCAAGAATAA

>In-frame_FRAS1_ENST00000325942_chr4_78987170_+_MRPL1_ENST00000315567_chr4_78870951_+_932nt
AACTTTAAAAAGCTGCTTCGGACAAACCAGAGCCAGGATTTCCACTGTCGGGGACCCGGGATCGGAAGGGTCTAGCCCGAGGGAAATGCT
GGAAGATCCCATCGGCCAGTGACCAGCAACTTTCCGGCGAGATTTTGACGCGGAGAACTGTGCTCTGCCTCCTCTTATTCTCCCAAAGCT
CACGTTGGCGTCCTGCCTTGCGGGGGAACTCGGCGCGCTCTCTGCCTGAGCAGCGAGTGAATTGAACCCCAGCCCGCTCCGGCGCCTCCG
GGCTGATGAGTGTCGCTCTCCGCCCGTCCATCTCTTTTTCCCGGAGGTAAAGGCCCGCGGTCCCCCACCTTCAGTGCGCCCGGGTTCCAA
GCGCCGGAGCCAGCGTTTTGGCGGAGCCGCTTCTTGGATGCTGAAGGCTGGGCTCCTCCATCGTGGGTGCCGAGGCGGCGATGGGTGTCC
TCAAAGTGTGGCTCGGGCTGGCCCTAGCGTTGGCGGAATTTGCAGTATTGCCTCATCATTCCGAAGGTGCTTGTGTCTATCAGGATTCCT
TGTTGGCGTTGGATATGTCAAGTGACCAGATAGCTGCCAATCTGCAAGCAGTTATTAATGAAGTTTGTAGGCACAGACCGCTGAATTTGG
GTCCCTTTGTGGTACGTGCTTTCCTTCGTAGTTCAACAAGTGAAGGTTTATTACTGAAGATTGATCCATTGTTGCCTAAAGAAGTAAAAA
ATGAAGAAAGTGAAAAAGAAGATGCCTAAATGTGGTGAATTGTGAAATTACTTTCAGTGGTTTAAGAAGCAATGGAGAAAATGATAATAC
AGCATAATTTTTACATTTGATGTCTTGTTATTGATCATACTTGAAAGTGAACTTTAACATTGAAAAATCGTACAGTCATTTCAAGAATAA

>In-frame_FRAS1_ENST00000264895_chr4_78987170_+_MRPL1_ENST00000315567_chr4_78870951_+_932nt
AACTTTAAAAAGCTGCTTCGGACAAACCAGAGCCAGGATTTCCACTGTCGGGGACCCGGGATCGGAAGGGTCTAGCCCGAGGGAAATGCT
GGAAGATCCCATCGGCCAGTGACCAGCAACTTTCCGGCGAGATTTTGACGCGGAGAACTGTGCTCTGCCTCCTCTTATTCTCCCAAAGCT
CACGTTGGCGTCCTGCCTTGCGGGGGAACTCGGCGCGCTCTCTGCCTGAGCAGCGAGTGAATTGAACCCCAGCCCGCTCCGGCGCCTCCG
GGCTGATGAGTGTCGCTCTCCGCCCGTCCATCTCTTTTTCCCGGAGGTAAAGGCCCGCGGTCCCCCACCTTCAGTGCGCCCGGGTTCCAA
GCGCCGGAGCCAGCGTTTTGGCGGAGCCGCTTCTTGGATGCTGAAGGCTGGGCTCCTCCATCGTGGGTGCCGAGGCGGCGATGGGTGTCC
TCAAAGTGTGGCTCGGGCTGGCCCTAGCGTTGGCGGAATTTGCAGTATTGCCTCATCATTCCGAAGGTGCTTGTGTCTATCAGGATTCCT
TGTTGGCGTTGGATATGTCAAGTGACCAGATAGCTGCCAATCTGCAAGCAGTTATTAATGAAGTTTGTAGGCACAGACCGCTGAATTTGG
GTCCCTTTGTGGTACGTGCTTTCCTTCGTAGTTCAACAAGTGAAGGTTTATTACTGAAGATTGATCCATTGTTGCCTAAAGAAGTAAAAA
ATGAAGAAAGTGAAAAAGAAGATGCCTAAATGTGGTGAATTGTGAAATTACTTTCAGTGGTTTAAGAAGCAATGGAGAAAATGATAATAC
AGCATAATTTTTACATTTGATGTCTTGTTATTGATCATACTTGAAAGTGAACTTTAACATTGAAAAATCGTACAGTCATTTCAAGAATAA

>In-frame_FRAS1_ENST00000264899_chr4_78979239_+_MRPL1_ENST00000315567_chr4_78792898_+_1646nt
AACTTTAAAAAGCTGCTTCGGACAAACCAGAGCCAGGATTTCCACTGTCGGGGACCCGGGATCGGAAGGGTCTAGCCCGAGGGAAATGCT
GGAAGATCCCATCGGCCAGTGACCAGCAACTTTCCGGCGAGATTTTGACGCGGAGAACTGTGCTCTGCCTCCTCTTATTCTCCCAAAGCT
CACGTTGGCGTCCTGCCTTGCGGGGGAACTCGGCGCGCTCTCTGCCTGAGCAGCGAGTGAATTGAACCCCAGCCCGCTCCGGCGCCTCCG
GGCTGATGAGTGTCGCTCTCCGCCCGTCCATCTCTTTTTCCCGGAGGTAAAGGCCCGCGGTCCCCCACCTTCAGTGCGCCCGGGTTCCAA
GCGCCGGAGCCAGCGTTTTGGCGGAGCCGCTTCTTGGATGCTGAAGGCTGGGCTCCTCCATCGTGGGTGCCGAGGCGGCGATGGGTGTCC
TCAAAGTGTGGCTCGGGCTGGCCCTAGCGTTGGCGGAATTTGCAGTATTGCCTCATCATTCCGAAGCCTTGATACATCATCAAAGGCATA
GCCTTTCCAAGATGGTTTATCAGACATCACTTTGTTCTTGTTCTGTAAACATCCGAGTGCCCAACAGACATTTTGCTGCTGCTACAAAGT
CTGCAAAGAAAACAAAAAAAGGTGCTAAAGAAAAAACACCAGATGAGAAAAAAGATGAAATAGAAAAAATAAAAGCATATCCCTATATGG
AAGGCGAACCTGAGGATGATGTCTATTTAAAACGCTTATACCCGAGACAGATATATGAGGTGGAGAAAGCTGTTCACTTACTTAAGAAAT
TTCAAATTCTTGACTTTACTAGTCCAAAGCAAAGTGTTTATCTTGATTTGACACTGGATATGGCACTGGGAAAGAAGAAAAACGTGGAGC
CATTTACCAGTGTTCTTAGTTTGCCATACCCATTTGCTTCCGAAATCAATAAAGTTGCTGTATTTACAGAGAATGCATCAGAGGTCAAAA
TAGCGGAAGAAAATGGAGCTGCATTTGCAGGAGGCACTAGTCTGATACAGAAGATTTGGGATGATGAAATTGTTGCAGACTTTTACGTAG
CTGTTCCAGAAATAATGCCTGAACTTAATCGATTAAGGAAGAAACTGAATAAAAAATATCCAAAGCTTTCTCGAAATTCCATTGGCCGTG
ACATCCCCAAAATGCTTGAATTATTTAAAAATGGACATGAAATTAAGGTAGATGAAGAAAGGGAGAACTTTCTCCAGACCAAAATAGCAA
CATTGGATATGTCAAGTGACCAGATAGCTGCCAATCTGCAAGCAGTTATTAATGAAGTTTGTAGGCACAGACCGCTGAATTTGGGTCCCT
TTGTGGTACGTGCTTTCCTTCGTAGTTCAACAAGTGAAGGTTTATTACTGAAGATTGATCCATTGTTGCCTAAAGAAGTAAAAAATGAAG
AAAGTGAAAAAGAAGATGCCTAAATGTGGTGAATTGTGAAATTACTTTCAGTGGTTTAAGAAGCAATGGAGAAAATGATAATACAGCATA
ATTTTTACATTTGATGTCTTGTTATTGATCATACTTGAAAGTGAACTTTAACATTGAAAAATCGTACAGTCATTTCAAGAATAAGAAAAT

>In-frame_FRAS1_ENST00000325942_chr4_78979239_+_MRPL1_ENST00000315567_chr4_78792898_+_1646nt
AACTTTAAAAAGCTGCTTCGGACAAACCAGAGCCAGGATTTCCACTGTCGGGGACCCGGGATCGGAAGGGTCTAGCCCGAGGGAAATGCT
GGAAGATCCCATCGGCCAGTGACCAGCAACTTTCCGGCGAGATTTTGACGCGGAGAACTGTGCTCTGCCTCCTCTTATTCTCCCAAAGCT
CACGTTGGCGTCCTGCCTTGCGGGGGAACTCGGCGCGCTCTCTGCCTGAGCAGCGAGTGAATTGAACCCCAGCCCGCTCCGGCGCCTCCG
GGCTGATGAGTGTCGCTCTCCGCCCGTCCATCTCTTTTTCCCGGAGGTAAAGGCCCGCGGTCCCCCACCTTCAGTGCGCCCGGGTTCCAA
GCGCCGGAGCCAGCGTTTTGGCGGAGCCGCTTCTTGGATGCTGAAGGCTGGGCTCCTCCATCGTGGGTGCCGAGGCGGCGATGGGTGTCC
TCAAAGTGTGGCTCGGGCTGGCCCTAGCGTTGGCGGAATTTGCAGTATTGCCTCATCATTCCGAAGCCTTGATACATCATCAAAGGCATA
GCCTTTCCAAGATGGTTTATCAGACATCACTTTGTTCTTGTTCTGTAAACATCCGAGTGCCCAACAGACATTTTGCTGCTGCTACAAAGT
CTGCAAAGAAAACAAAAAAAGGTGCTAAAGAAAAAACACCAGATGAGAAAAAAGATGAAATAGAAAAAATAAAAGCATATCCCTATATGG
AAGGCGAACCTGAGGATGATGTCTATTTAAAACGCTTATACCCGAGACAGATATATGAGGTGGAGAAAGCTGTTCACTTACTTAAGAAAT
TTCAAATTCTTGACTTTACTAGTCCAAAGCAAAGTGTTTATCTTGATTTGACACTGGATATGGCACTGGGAAAGAAGAAAAACGTGGAGC
CATTTACCAGTGTTCTTAGTTTGCCATACCCATTTGCTTCCGAAATCAATAAAGTTGCTGTATTTACAGAGAATGCATCAGAGGTCAAAA
TAGCGGAAGAAAATGGAGCTGCATTTGCAGGAGGCACTAGTCTGATACAGAAGATTTGGGATGATGAAATTGTTGCAGACTTTTACGTAG
CTGTTCCAGAAATAATGCCTGAACTTAATCGATTAAGGAAGAAACTGAATAAAAAATATCCAAAGCTTTCTCGAAATTCCATTGGCCGTG
ACATCCCCAAAATGCTTGAATTATTTAAAAATGGACATGAAATTAAGGTAGATGAAGAAAGGGAGAACTTTCTCCAGACCAAAATAGCAA
CATTGGATATGTCAAGTGACCAGATAGCTGCCAATCTGCAAGCAGTTATTAATGAAGTTTGTAGGCACAGACCGCTGAATTTGGGTCCCT
TTGTGGTACGTGCTTTCCTTCGTAGTTCAACAAGTGAAGGTTTATTACTGAAGATTGATCCATTGTTGCCTAAAGAAGTAAAAAATGAAG
AAAGTGAAAAAGAAGATGCCTAAATGTGGTGAATTGTGAAATTACTTTCAGTGGTTTAAGAAGCAATGGAGAAAATGATAATACAGCATA
ATTTTTACATTTGATGTCTTGTTATTGATCATACTTGAAAGTGAACTTTAACATTGAAAAATCGTACAGTCATTTCAAGAATAAGAAAAT

>In-frame_FRAS1_ENST00000264895_chr4_78979239_+_MRPL1_ENST00000315567_chr4_78792898_+_1646nt
AACTTTAAAAAGCTGCTTCGGACAAACCAGAGCCAGGATTTCCACTGTCGGGGACCCGGGATCGGAAGGGTCTAGCCCGAGGGAAATGCT
GGAAGATCCCATCGGCCAGTGACCAGCAACTTTCCGGCGAGATTTTGACGCGGAGAACTGTGCTCTGCCTCCTCTTATTCTCCCAAAGCT
CACGTTGGCGTCCTGCCTTGCGGGGGAACTCGGCGCGCTCTCTGCCTGAGCAGCGAGTGAATTGAACCCCAGCCCGCTCCGGCGCCTCCG
GGCTGATGAGTGTCGCTCTCCGCCCGTCCATCTCTTTTTCCCGGAGGTAAAGGCCCGCGGTCCCCCACCTTCAGTGCGCCCGGGTTCCAA
GCGCCGGAGCCAGCGTTTTGGCGGAGCCGCTTCTTGGATGCTGAAGGCTGGGCTCCTCCATCGTGGGTGCCGAGGCGGCGATGGGTGTCC
TCAAAGTGTGGCTCGGGCTGGCCCTAGCGTTGGCGGAATTTGCAGTATTGCCTCATCATTCCGAAGCCTTGATACATCATCAAAGGCATA
GCCTTTCCAAGATGGTTTATCAGACATCACTTTGTTCTTGTTCTGTAAACATCCGAGTGCCCAACAGACATTTTGCTGCTGCTACAAAGT
CTGCAAAGAAAACAAAAAAAGGTGCTAAAGAAAAAACACCAGATGAGAAAAAAGATGAAATAGAAAAAATAAAAGCATATCCCTATATGG
AAGGCGAACCTGAGGATGATGTCTATTTAAAACGCTTATACCCGAGACAGATATATGAGGTGGAGAAAGCTGTTCACTTACTTAAGAAAT
TTCAAATTCTTGACTTTACTAGTCCAAAGCAAAGTGTTTATCTTGATTTGACACTGGATATGGCACTGGGAAAGAAGAAAAACGTGGAGC
CATTTACCAGTGTTCTTAGTTTGCCATACCCATTTGCTTCCGAAATCAATAAAGTTGCTGTATTTACAGAGAATGCATCAGAGGTCAAAA
TAGCGGAAGAAAATGGAGCTGCATTTGCAGGAGGCACTAGTCTGATACAGAAGATTTGGGATGATGAAATTGTTGCAGACTTTTACGTAG
CTGTTCCAGAAATAATGCCTGAACTTAATCGATTAAGGAAGAAACTGAATAAAAAATATCCAAAGCTTTCTCGAAATTCCATTGGCCGTG
ACATCCCCAAAATGCTTGAATTATTTAAAAATGGACATGAAATTAAGGTAGATGAAGAAAGGGAGAACTTTCTCCAGACCAAAATAGCAA
CATTGGATATGTCAAGTGACCAGATAGCTGCCAATCTGCAAGCAGTTATTAATGAAGTTTGTAGGCACAGACCGCTGAATTTGGGTCCCT
TTGTGGTACGTGCTTTCCTTCGTAGTTCAACAAGTGAAGGTTTATTACTGAAGATTGATCCATTGTTGCCTAAAGAAGTAAAAAATGAAG
AAAGTGAAAAAGAAGATGCCTAAATGTGGTGAATTGTGAAATTACTTTCAGTGGTTTAAGAAGCAATGGAGAAAATGATAATACAGCATA
ATTTTTACATTTGATGTCTTGTTATTGATCATACTTGAAAGTGAACTTTAACATTGAAAAATCGTACAGTCATTTCAAGAATAAGAAAAT


Top

FusionGenePPI for FRAS1_MRPL1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page

.

check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors
FRAS1KLK11, TAZ, NXPH2, SUSD4, KLK5, ZPBP2, PVRIG, QPCT, PTPRK, CHST8, WNT4, LIPH, GPHA2, ZFP41, DKKL1, DEFA5, PSG8, ZNF408, SCGB1D1, ST8SIA4, MGAT4C, GML, IFNE, LRRTM1, ADAMTS4, PRG3, XAGE1B, FCGR1A, OS9, LYZL1, LRRC4C, SLAMF1, TRIM25MRPL1ICT1, CUL3, CAND1, APP, MRPS7, MRPL10, MRPL11, MRPL4, MRPL12, HSPA1L, DLAT, ILF3, SDHA, ACAD9, TUFM, MSLN, MMGT1, SOX2, GOPC, RPL13, MRPL28, ZC3H3, RPS8, HNRNPA1, MRPL39, MRPS30, MRPL47, ATP6V1H, CORO1B, CORO1C, MRTO4, RPS20, RPL12, SETD4, NDUFAF1, APBB2, MRPL49, SLC25A10, PI4KA, SSB, IRS2, PTTG1, MRPL33, MRPL19, MRPL3, MRPL42, MRPL13, MRPL18, MRPL15, MRPL2, MRPL37, MRPL30, MRPL35, MRPL50, MRPL16, PARP16, MRPL20, MRPS18A, PRPF40A, NCKAP5L, MRPL17, MRPL14, MRPL40, MRPL38, MRPL34, MRPL32, MRPL9, MRPL44, MRPL57, BRCC3, MRPL45, MRPL43, GADD45GIP1, MRPL53, MRPL52, SLC30A7, MRPL21, SUGCT, C6orf203, COQ4, MRPL41, CIRBP, RBM3, CYLD


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


Top

RelatedDrugs for FRAS1_MRPL1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

Top

RelatedDiseases for FRAS1_MRPL1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneFRAS1C0024433Macrostomia1CTD_human
HgeneFRAS1C0265233Cryptophthalmos syndrome1CTD_human;ORPHANET