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Fusion gene ID: 13710 |
FusionGeneSummary for FNIP2_LARP7 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: FNIP2_LARP7 | Fusion gene ID: 13710 | Hgene | Tgene | Gene symbol | FNIP2 | LARP7 | Gene ID | 57600 | 51574 |
| Gene name | folliculin interacting protein 2 | La ribonucleoprotein domain family member 7 | |
| Synonyms | FNIPL|MAPO1 | ALAZS|HDCMA18P|PIP7S | |
| Cytomap | 4q32.1 | 4q25 | |
| Type of gene | protein-coding | protein-coding | |
| Description | folliculin-interacting protein 2FNIP1-like proteinO6-methylguanine-induced apoptosis 1 protein | la-related protein 7P-TEFb-interaction protein for 7SK stability | |
| Modification date | 20180519 | 20180522 | |
| UniProtAcc | Q9P278 | Q4G0J3 | |
| Ensembl transtripts involved in fusion gene | ENST00000264433, ENST00000379346, ENST00000505445, | ENST00000344442, ENST00000509061, ENST00000324052, ENST00000503898, | |
| Fusion gene scores | * DoF score | 9 X 5 X 6=270 | 5 X 5 X 3=75 |
| # samples | 9 | 5 | |
| ** MAII score | log2(9/270*10)=-1.58496250072116 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(5/75*10)=-0.584962500721156 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: FNIP2 [Title/Abstract] AND LARP7 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | FNIP2 | GO:0000122 | negative regulation of transcription by RNA polymerase II | 21209915 |
| Hgene | FNIP2 | GO:0001932 | regulation of protein phosphorylation | 18663353 |
| Hgene | FNIP2 | GO:0006468 | protein phosphorylation | 18663353 |
| Hgene | FNIP2 | GO:0031334 | positive regulation of protein complex assembly | 25126726 |
| Hgene | FNIP2 | GO:0033138 | positive regulation of peptidyl-serine phosphorylation | 19914239 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | BRCA | TCGA-AO-A1KR-01A | FNIP2 | chr4 | 159756628 | + | LARP7 | chr4 | 113571617 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000264433 | ENST00000344442 | FNIP2 | chr4 | 159756628 | + | LARP7 | chr4 | 113571617 | + |
| In-frame | ENST00000264433 | ENST00000509061 | FNIP2 | chr4 | 159756628 | + | LARP7 | chr4 | 113571617 | + |
| In-frame | ENST00000264433 | ENST00000324052 | FNIP2 | chr4 | 159756628 | + | LARP7 | chr4 | 113571617 | + |
| 5CDS-intron | ENST00000264433 | ENST00000503898 | FNIP2 | chr4 | 159756628 | + | LARP7 | chr4 | 113571617 | + |
| In-frame | ENST00000379346 | ENST00000344442 | FNIP2 | chr4 | 159756628 | + | LARP7 | chr4 | 113571617 | + |
| In-frame | ENST00000379346 | ENST00000509061 | FNIP2 | chr4 | 159756628 | + | LARP7 | chr4 | 113571617 | + |
| In-frame | ENST00000379346 | ENST00000324052 | FNIP2 | chr4 | 159756628 | + | LARP7 | chr4 | 113571617 | + |
| 5CDS-intron | ENST00000379346 | ENST00000503898 | FNIP2 | chr4 | 159756628 | + | LARP7 | chr4 | 113571617 | + |
| intron-3CDS | ENST00000505445 | ENST00000344442 | FNIP2 | chr4 | 159756628 | + | LARP7 | chr4 | 113571617 | + |
| intron-3CDS | ENST00000505445 | ENST00000509061 | FNIP2 | chr4 | 159756628 | + | LARP7 | chr4 | 113571617 | + |
| intron-3CDS | ENST00000505445 | ENST00000324052 | FNIP2 | chr4 | 159756628 | + | LARP7 | chr4 | 113571617 | + |
| intron-intron | ENST00000505445 | ENST00000503898 | FNIP2 | chr4 | 159756628 | + | LARP7 | chr4 | 113571617 | + |
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FusionProtFeatures for FNIP2_LARP7 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| FNIP2 | LARP7 |
| Acts as a co-chaperone of HSP90AA1. Inhibits the ATPaseactivity of HSP90AA1 leading to reduction in its chaperoneactivity. Facilitates the binding of client protein FLCN toHSP90AA1 (PubMed:27353360). May play a role in the signaltransduction pathway of apoptosis induced by O6-methylguanine-mispaired lesions (By similarity). May be involved in energyand/or nutrient sensing through the AMPK and mTOR signalingpathways (PubMed:18403135). May regulate phosphorylation ofRPS6KB1 (PubMed:18663353). {ECO:0000250|UniProtKB:Q80TD3,ECO:0000269|PubMed:18403135, ECO:0000269|PubMed:18663353,ECO:0000269|PubMed:27353360}. | Negative transcriptional regulator of polymerase IIgenes, acting by means of the 7SK RNP system. Within the 7SK RNPcomplex, the positive transcription elongation factor b (P-TEFb)is sequestered in an inactive form, preventing RNA polymerase IIphosphorylation and subsequent transcriptional elongation.{ECO:0000269|PubMed:18249148, ECO:0000269|PubMed:18483487}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | FNIP2 | chr4:159756628 | chr4:113571617 | ENST00000264433 | + | 7 | 17 | 95_116 | 242 | 1115 | Compositional bias | Note=Ser-rich |
| Hgene | FNIP2 | chr4:159756628 | chr4:113571617 | ENST00000379346 | + | 7 | 17 | 242_265 | 265 | 1138 | Compositional bias | Note=Ser-rich |
| Hgene | FNIP2 | chr4:159756628 | chr4:113571617 | ENST00000379346 | + | 7 | 17 | 95_116 | 265 | 1138 | Compositional bias | Note=Ser-rich |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >FNIP2 | chr4:159756628 | chr4:113571617 | ENST00000264433 | + | 7 | 17 | 242_265 | 242 | 1115 | Compositional bias | Note=Ser-rich |
| Hgene | >FNIP2 | chr4:159756628 | chr4:113571617 | ENST00000264433 | + | 7 | 17 | 1050_1105 | 242 | 1115 | Domain | dDENN FNIP1/2-type |
| Hgene | >FNIP2 | chr4:159756628 | chr4:113571617 | ENST00000264433 | + | 7 | 17 | 42_460 | 242 | 1115 | Domain | uDENN FNIP1/2-type |
| Hgene | >FNIP2 | chr4:159756628 | chr4:113571617 | ENST00000264433 | + | 7 | 17 | 468_1040 | 242 | 1115 | Domain | cDENN FNIP1/2-type |
| Hgene | >FNIP2 | chr4:159756628 | chr4:113571617 | ENST00000379346 | + | 7 | 17 | 1050_1105 | 265 | 1138 | Domain | dDENN FNIP1/2-type |
| Hgene | >FNIP2 | chr4:159756628 | chr4:113571617 | ENST00000379346 | + | 7 | 17 | 42_460 | 265 | 1138 | Domain | uDENN FNIP1/2-type |
| Hgene | >FNIP2 | chr4:159756628 | chr4:113571617 | ENST00000379346 | + | 7 | 17 | 468_1040 | 265 | 1138 | Domain | cDENN FNIP1/2-type |
| Tgene | LARP7 | chr4:159756628 | chr4:113571617 | ENST00000324052 | + | 8 | 13 | 202_368 | 431 | 583 | Compositional bias | Note=Lys-rich |
| Tgene | LARP7 | chr4:159756628 | chr4:113571617 | ENST00000344442 | + | 8 | 13 | 202_368 | 431 | 583 | Compositional bias | Note=Lys-rich |
| Tgene | LARP7 | chr4:159756628 | chr4:113571617 | ENST00000509061 | + | 10 | 15 | 202_368 | 438 | 590 | Compositional bias | Note=Lys-rich |
| Tgene | LARP7 | chr4:159756628 | chr4:113571617 | ENST00000324052 | + | 8 | 13 | 125_203 | 431 | 583 | Domain | RRM |
| Tgene | LARP7 | chr4:159756628 | chr4:113571617 | ENST00000324052 | + | 8 | 13 | 28_122 | 431 | 583 | Domain | HTH La-type RNA-binding |
| Tgene | LARP7 | chr4:159756628 | chr4:113571617 | ENST00000344442 | + | 8 | 13 | 125_203 | 431 | 583 | Domain | RRM |
| Tgene | LARP7 | chr4:159756628 | chr4:113571617 | ENST00000344442 | + | 8 | 13 | 28_122 | 431 | 583 | Domain | HTH La-type RNA-binding |
| Tgene | LARP7 | chr4:159756628 | chr4:113571617 | ENST00000509061 | + | 10 | 15 | 125_203 | 438 | 590 | Domain | RRM |
| Tgene | LARP7 | chr4:159756628 | chr4:113571617 | ENST00000509061 | + | 10 | 15 | 28_122 | 438 | 590 | Domain | HTH La-type RNA-binding |
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FusionGeneSequence for FNIP2_LARP7 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_FNIP2_ENST00000264433_chr4_159756628_+_LARP7_ENST00000344442_chr4_113571617_+_394aa MAPTLLQKLFNKRGSSGSSAAASAQGRAPKEGPAFSWSCSEFDLNEIRLIVYQDCDRRGRQVLFDSKAVQKIEEVTAQKTEDVPIKISAK CCQGSSSVSSSSSSSISSHSSSGGSSHHAKEQLPKYQYTRPASDVNMLGEMMFGSVAMSYKGSTLKIHYIRSPPQLMISKVFSARMGSFC GSTNNLQDSFEYINQDPNLGKLNTNQNSLGPCRTGSNLAHSTPVDMPSRGQNEDRDSGIARSAANREECRTQEKVNATGPQFVSGVIVKI ISTEPLPGRKQVRDTLAAISEVLYVDLLEGDTECHARFKTPEDAQAVINAYTEINKKHCWKLEILSGDHEQRYWQKILVDRQAKLNQPRE >In-frame_FNIP2_ENST00000264433_chr4_159756628_+_LARP7_ENST00000509061_chr4_113571617_+_394aa MAPTLLQKLFNKRGSSGSSAAASAQGRAPKEGPAFSWSCSEFDLNEIRLIVYQDCDRRGRQVLFDSKAVQKIEEVTAQKTEDVPIKISAK CCQGSSSVSSSSSSSISSHSSSGGSSHHAKEQLPKYQYTRPASDVNMLGEMMFGSVAMSYKGSTLKIHYIRSPPQLMISKVFSARMGSFC GSTNNLQDSFEYINQDPNLGKLNTNQNSLGPCRTGSNLAHSTPVDMPSRGQNEDRDSGIARSAANREECRTQEKVNATGPQFVSGVIVKI ISTEPLPGRKQVRDTLAAISEVLYVDLLEGDTECHARFKTPEDAQAVINAYTEINKKHCWKLEILSGDHEQRYWQKILVDRQAKLNQPRE >In-frame_FNIP2_ENST00000264433_chr4_159756628_+_LARP7_ENST00000324052_chr4_113571617_+_394aa MAPTLLQKLFNKRGSSGSSAAASAQGRAPKEGPAFSWSCSEFDLNEIRLIVYQDCDRRGRQVLFDSKAVQKIEEVTAQKTEDVPIKISAK CCQGSSSVSSSSSSSISSHSSSGGSSHHAKEQLPKYQYTRPASDVNMLGEMMFGSVAMSYKGSTLKIHYIRSPPQLMISKVFSARMGSFC GSTNNLQDSFEYINQDPNLGKLNTNQNSLGPCRTGSNLAHSTPVDMPSRGQNEDRDSGIARSAANREECRTQEKVNATGPQFVSGVIVKI ISTEPLPGRKQVRDTLAAISEVLYVDLLEGDTECHARFKTPEDAQAVINAYTEINKKHCWKLEILSGDHEQRYWQKILVDRQAKLNQPRE >In-frame_FNIP2_ENST00000379346_chr4_159756628_+_LARP7_ENST00000344442_chr4_113571617_+_417aa MCGGTANTTNQPESWQDSARCVSDAVPGAGRIYRALLCTKIKKHTGVDRSTDHTELDNSWSCSEFDLNEIRLIVYQDCDRRGRQVLFDSK AVQKIEEVTAQKTEDVPIKISAKCCQGSSSVSSSSSSSISSHSSSGGSSHHAKEQLPKYQYTRPASDVNMLGEMMFGSVAMSYKGSTLKI HYIRSPPQLMISKVFSARMGSFCGSTNNLQDSFEYINQDPNLGKLNTNQNSLGPCRTGSNLAHSTPVDMPSRGQNEDRDSGIARSAANRE ECRTQEKVNATGPQFVSGVIVKIISTEPLPGRKQVRDTLAAISEVLYVDLLEGDTECHARFKTPEDAQAVINAYTEINKKHCWKLEILSG >In-frame_FNIP2_ENST00000379346_chr4_159756628_+_LARP7_ENST00000509061_chr4_113571617_+_417aa MCGGTANTTNQPESWQDSARCVSDAVPGAGRIYRALLCTKIKKHTGVDRSTDHTELDNSWSCSEFDLNEIRLIVYQDCDRRGRQVLFDSK AVQKIEEVTAQKTEDVPIKISAKCCQGSSSVSSSSSSSISSHSSSGGSSHHAKEQLPKYQYTRPASDVNMLGEMMFGSVAMSYKGSTLKI HYIRSPPQLMISKVFSARMGSFCGSTNNLQDSFEYINQDPNLGKLNTNQNSLGPCRTGSNLAHSTPVDMPSRGQNEDRDSGIARSAANRE ECRTQEKVNATGPQFVSGVIVKIISTEPLPGRKQVRDTLAAISEVLYVDLLEGDTECHARFKTPEDAQAVINAYTEINKKHCWKLEILSG >In-frame_FNIP2_ENST00000379346_chr4_159756628_+_LARP7_ENST00000324052_chr4_113571617_+_417aa MCGGTANTTNQPESWQDSARCVSDAVPGAGRIYRALLCTKIKKHTGVDRSTDHTELDNSWSCSEFDLNEIRLIVYQDCDRRGRQVLFDSK AVQKIEEVTAQKTEDVPIKISAKCCQGSSSVSSSSSSSISSHSSSGGSSHHAKEQLPKYQYTRPASDVNMLGEMMFGSVAMSYKGSTLKI HYIRSPPQLMISKVFSARMGSFCGSTNNLQDSFEYINQDPNLGKLNTNQNSLGPCRTGSNLAHSTPVDMPSRGQNEDRDSGIARSAANRE ECRTQEKVNATGPQFVSGVIVKIISTEPLPGRKQVRDTLAAISEVLYVDLLEGDTECHARFKTPEDAQAVINAYTEINKKHCWKLEILSG |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_FNIP2_ENST00000264433_chr4_159756628_+_LARP7_ENST00000344442_chr4_113571617_+_1182nt ATGGCCCCGACCCTGCTCCAGAAGCTCTTCAACAAAAGGGGCAGCAGCGGCAGCTCCGCGGCGGCGTCTGCCCAGGGCAGGGCTCCTAAG GAAGGACCCGCCTTTAGTTGGTCATGTTCGGAGTTTGACCTGAATGAGATTCGCCTGATAGTTTACCAGGACTGTGACAGGAGAGGCAGA CAAGTCTTGTTTGACTCTAAAGCTGTTCAAAAGATTGAGGAGGTGACAGCTCAGAAAACAGAGGATGTTCCTATTAAAATATCAGCCAAG TGCTGCCAGGGAAGCAGCAGTGTCAGCAGCAGTAGCAGCAGCAGCATCTCTTCCCACAGTTCTTCTGGGGGATCTTCACATCATGCTAAG GAACAGCTTCCAAAGTACCAGTACACAAGACCAGCTTCCGATGTCAACATGTTAGGGGAAATGATGTTTGGCTCAGTTGCCATGAGTTAC AAAGGCTCCACCTTAAAGATACACTACATACGTTCTCCTCCACAACTGATGATTAGTAAAGTCTTCTCTGCTAGAATGGGCAGCTTCTGT GGAAGTACAAATAACTTGCAAGACAGCTTTGAGTACATCAACCAAGATCCTAATTTGGGAAAACTGAACACAAATCAAAATAGTTTGGGT CCTTGTCGTACTGGAAGTAACCTAGCACACAGCACACCAGTTGATATGCCAAGCAGAGGACAGAATGAAGACAGGGACAGTGGCATTGCT CGATCAGCAGCCAACAGGGAAGAGTGTCGCACCCAGGAGAAAGTTAATGCAACAGGACCACAGTTCGTGAGTGGAGTGATTGTGAAGATC ATTAGCACAGAGCCTCTACCTGGCAGGAAACAAGTCCGGGATACTTTGGCAGCAATCTCAGAAGTTCTTTATGTTGATTTGCTAGAAGGG GATACAGAATGCCATGCTAGATTTAAAACTCCTGAGGATGCTCAAGCAGTAATAAATGCCTATACAGAAATTAACAAGAAACACTGCTGG AAACTCGAGATCCTTTCTGGTGATCACGAACAAAGGTATTGGCAGAAGATTTTGGTTGATAGACAGGCAAAACTTAATCAGCCTCGGGAA AAGAAAAGAGGCACTGAAAAGTTAATCACCAAAGCTGAAAAGATTAGACTGGCAAAGACTCAACAAGCGAGTAAACATATAAGATTTTCT >In-frame_FNIP2_ENST00000264433_chr4_159756628_+_LARP7_ENST00000509061_chr4_113571617_+_1182nt ATGGCCCCGACCCTGCTCCAGAAGCTCTTCAACAAAAGGGGCAGCAGCGGCAGCTCCGCGGCGGCGTCTGCCCAGGGCAGGGCTCCTAAG GAAGGACCCGCCTTTAGTTGGTCATGTTCGGAGTTTGACCTGAATGAGATTCGCCTGATAGTTTACCAGGACTGTGACAGGAGAGGCAGA CAAGTCTTGTTTGACTCTAAAGCTGTTCAAAAGATTGAGGAGGTGACAGCTCAGAAAACAGAGGATGTTCCTATTAAAATATCAGCCAAG TGCTGCCAGGGAAGCAGCAGTGTCAGCAGCAGTAGCAGCAGCAGCATCTCTTCCCACAGTTCTTCTGGGGGATCTTCACATCATGCTAAG GAACAGCTTCCAAAGTACCAGTACACAAGACCAGCTTCCGATGTCAACATGTTAGGGGAAATGATGTTTGGCTCAGTTGCCATGAGTTAC AAAGGCTCCACCTTAAAGATACACTACATACGTTCTCCTCCACAACTGATGATTAGTAAAGTCTTCTCTGCTAGAATGGGCAGCTTCTGT GGAAGTACAAATAACTTGCAAGACAGCTTTGAGTACATCAACCAAGATCCTAATTTGGGAAAACTGAACACAAATCAAAATAGTTTGGGT CCTTGTCGTACTGGAAGTAACCTAGCACACAGCACACCAGTTGATATGCCAAGCAGAGGACAGAATGAAGACAGGGACAGTGGCATTGCT CGATCAGCAGCCAACAGGGAAGAGTGTCGCACCCAGGAGAAAGTTAATGCAACAGGACCACAGTTCGTGAGTGGAGTGATTGTGAAGATC ATTAGCACAGAGCCTCTACCTGGCAGGAAACAAGTCCGGGATACTTTGGCAGCAATCTCAGAAGTTCTTTATGTTGATTTGCTAGAAGGG GATACAGAATGCCATGCTAGATTTAAAACTCCTGAGGATGCTCAAGCAGTAATAAATGCCTATACAGAAATTAACAAGAAACACTGCTGG AAACTCGAGATCCTTTCTGGTGATCACGAACAAAGGTATTGGCAGAAGATTTTGGTTGATAGACAGGCAAAACTTAATCAGCCTCGGGAA AAGAAAAGAGGCACTGAAAAGTTAATCACCAAAGCTGAAAAGATTAGACTGGCAAAGACTCAACAAGCGAGTAAACATATAAGATTTTCT >In-frame_FNIP2_ENST00000264433_chr4_159756628_+_LARP7_ENST00000324052_chr4_113571617_+_1182nt ATGGCCCCGACCCTGCTCCAGAAGCTCTTCAACAAAAGGGGCAGCAGCGGCAGCTCCGCGGCGGCGTCTGCCCAGGGCAGGGCTCCTAAG GAAGGACCCGCCTTTAGTTGGTCATGTTCGGAGTTTGACCTGAATGAGATTCGCCTGATAGTTTACCAGGACTGTGACAGGAGAGGCAGA CAAGTCTTGTTTGACTCTAAAGCTGTTCAAAAGATTGAGGAGGTGACAGCTCAGAAAACAGAGGATGTTCCTATTAAAATATCAGCCAAG TGCTGCCAGGGAAGCAGCAGTGTCAGCAGCAGTAGCAGCAGCAGCATCTCTTCCCACAGTTCTTCTGGGGGATCTTCACATCATGCTAAG GAACAGCTTCCAAAGTACCAGTACACAAGACCAGCTTCCGATGTCAACATGTTAGGGGAAATGATGTTTGGCTCAGTTGCCATGAGTTAC AAAGGCTCCACCTTAAAGATACACTACATACGTTCTCCTCCACAACTGATGATTAGTAAAGTCTTCTCTGCTAGAATGGGCAGCTTCTGT GGAAGTACAAATAACTTGCAAGACAGCTTTGAGTACATCAACCAAGATCCTAATTTGGGAAAACTGAACACAAATCAAAATAGTTTGGGT CCTTGTCGTACTGGAAGTAACCTAGCACACAGCACACCAGTTGATATGCCAAGCAGAGGACAGAATGAAGACAGGGACAGTGGCATTGCT CGATCAGCAGCCAACAGGGAAGAGTGTCGCACCCAGGAGAAAGTTAATGCAACAGGACCACAGTTCGTGAGTGGAGTGATTGTGAAGATC ATTAGCACAGAGCCTCTACCTGGCAGGAAACAAGTCCGGGATACTTTGGCAGCAATCTCAGAAGTTCTTTATGTTGATTTGCTAGAAGGG GATACAGAATGCCATGCTAGATTTAAAACTCCTGAGGATGCTCAAGCAGTAATAAATGCCTATACAGAAATTAACAAGAAACACTGCTGG AAACTCGAGATCCTTTCTGGTGATCACGAACAAAGGTATTGGCAGAAGATTTTGGTTGATAGACAGGCAAAACTTAATCAGCCTCGGGAA AAGAAAAGAGGCACTGAAAAGTTAATCACCAAAGCTGAAAAGATTAGACTGGCAAAGACTCAACAAGCGAGTAAACATATAAGATTTTCT >In-frame_FNIP2_ENST00000379346_chr4_159756628_+_LARP7_ENST00000344442_chr4_113571617_+_1251nt ATGTGCGGCGGCACAGCGAACACCACAAACCAGCCAGAGAGCTGGCAAGACTCTGCCAGATGTGTGAGTGATGCTGTTCCTGGTGCTGGG AGGATTTACAGGGCGCTTTTATGCACAAAGATTAAAAAACACACCGGAGTAGACAGGAGCACTGACCACACGGAACTCGACAACAGTTGG TCATGTTCGGAGTTTGACCTGAATGAGATTCGCCTGATAGTTTACCAGGACTGTGACAGGAGAGGCAGACAAGTCTTGTTTGACTCTAAA GCTGTTCAAAAGATTGAGGAGGTGACAGCTCAGAAAACAGAGGATGTTCCTATTAAAATATCAGCCAAGTGCTGCCAGGGAAGCAGCAGT GTCAGCAGCAGTAGCAGCAGCAGCATCTCTTCCCACAGTTCTTCTGGGGGATCTTCACATCATGCTAAGGAACAGCTTCCAAAGTACCAG TACACAAGACCAGCTTCCGATGTCAACATGTTAGGGGAAATGATGTTTGGCTCAGTTGCCATGAGTTACAAAGGCTCCACCTTAAAGATA CACTACATACGTTCTCCTCCACAACTGATGATTAGTAAAGTCTTCTCTGCTAGAATGGGCAGCTTCTGTGGAAGTACAAATAACTTGCAA GACAGCTTTGAGTACATCAACCAAGATCCTAATTTGGGAAAACTGAACACAAATCAAAATAGTTTGGGTCCTTGTCGTACTGGAAGTAAC CTAGCACACAGCACACCAGTTGATATGCCAAGCAGAGGACAGAATGAAGACAGGGACAGTGGCATTGCTCGATCAGCAGCCAACAGGGAA GAGTGTCGCACCCAGGAGAAAGTTAATGCAACAGGACCACAGTTCGTGAGTGGAGTGATTGTGAAGATCATTAGCACAGAGCCTCTACCT GGCAGGAAACAAGTCCGGGATACTTTGGCAGCAATCTCAGAAGTTCTTTATGTTGATTTGCTAGAAGGGGATACAGAATGCCATGCTAGA TTTAAAACTCCTGAGGATGCTCAAGCAGTAATAAATGCCTATACAGAAATTAACAAGAAACACTGCTGGAAACTCGAGATCCTTTCTGGT GATCACGAACAAAGGTATTGGCAGAAGATTTTGGTTGATAGACAGGCAAAACTTAATCAGCCTCGGGAAAAGAAAAGAGGCACTGAAAAG >In-frame_FNIP2_ENST00000379346_chr4_159756628_+_LARP7_ENST00000509061_chr4_113571617_+_1251nt ATGTGCGGCGGCACAGCGAACACCACAAACCAGCCAGAGAGCTGGCAAGACTCTGCCAGATGTGTGAGTGATGCTGTTCCTGGTGCTGGG AGGATTTACAGGGCGCTTTTATGCACAAAGATTAAAAAACACACCGGAGTAGACAGGAGCACTGACCACACGGAACTCGACAACAGTTGG TCATGTTCGGAGTTTGACCTGAATGAGATTCGCCTGATAGTTTACCAGGACTGTGACAGGAGAGGCAGACAAGTCTTGTTTGACTCTAAA GCTGTTCAAAAGATTGAGGAGGTGACAGCTCAGAAAACAGAGGATGTTCCTATTAAAATATCAGCCAAGTGCTGCCAGGGAAGCAGCAGT GTCAGCAGCAGTAGCAGCAGCAGCATCTCTTCCCACAGTTCTTCTGGGGGATCTTCACATCATGCTAAGGAACAGCTTCCAAAGTACCAG TACACAAGACCAGCTTCCGATGTCAACATGTTAGGGGAAATGATGTTTGGCTCAGTTGCCATGAGTTACAAAGGCTCCACCTTAAAGATA CACTACATACGTTCTCCTCCACAACTGATGATTAGTAAAGTCTTCTCTGCTAGAATGGGCAGCTTCTGTGGAAGTACAAATAACTTGCAA GACAGCTTTGAGTACATCAACCAAGATCCTAATTTGGGAAAACTGAACACAAATCAAAATAGTTTGGGTCCTTGTCGTACTGGAAGTAAC CTAGCACACAGCACACCAGTTGATATGCCAAGCAGAGGACAGAATGAAGACAGGGACAGTGGCATTGCTCGATCAGCAGCCAACAGGGAA GAGTGTCGCACCCAGGAGAAAGTTAATGCAACAGGACCACAGTTCGTGAGTGGAGTGATTGTGAAGATCATTAGCACAGAGCCTCTACCT GGCAGGAAACAAGTCCGGGATACTTTGGCAGCAATCTCAGAAGTTCTTTATGTTGATTTGCTAGAAGGGGATACAGAATGCCATGCTAGA TTTAAAACTCCTGAGGATGCTCAAGCAGTAATAAATGCCTATACAGAAATTAACAAGAAACACTGCTGGAAACTCGAGATCCTTTCTGGT GATCACGAACAAAGGTATTGGCAGAAGATTTTGGTTGATAGACAGGCAAAACTTAATCAGCCTCGGGAAAAGAAAAGAGGCACTGAAAAG >In-frame_FNIP2_ENST00000379346_chr4_159756628_+_LARP7_ENST00000324052_chr4_113571617_+_1251nt ATGTGCGGCGGCACAGCGAACACCACAAACCAGCCAGAGAGCTGGCAAGACTCTGCCAGATGTGTGAGTGATGCTGTTCCTGGTGCTGGG AGGATTTACAGGGCGCTTTTATGCACAAAGATTAAAAAACACACCGGAGTAGACAGGAGCACTGACCACACGGAACTCGACAACAGTTGG TCATGTTCGGAGTTTGACCTGAATGAGATTCGCCTGATAGTTTACCAGGACTGTGACAGGAGAGGCAGACAAGTCTTGTTTGACTCTAAA GCTGTTCAAAAGATTGAGGAGGTGACAGCTCAGAAAACAGAGGATGTTCCTATTAAAATATCAGCCAAGTGCTGCCAGGGAAGCAGCAGT GTCAGCAGCAGTAGCAGCAGCAGCATCTCTTCCCACAGTTCTTCTGGGGGATCTTCACATCATGCTAAGGAACAGCTTCCAAAGTACCAG TACACAAGACCAGCTTCCGATGTCAACATGTTAGGGGAAATGATGTTTGGCTCAGTTGCCATGAGTTACAAAGGCTCCACCTTAAAGATA CACTACATACGTTCTCCTCCACAACTGATGATTAGTAAAGTCTTCTCTGCTAGAATGGGCAGCTTCTGTGGAAGTACAAATAACTTGCAA GACAGCTTTGAGTACATCAACCAAGATCCTAATTTGGGAAAACTGAACACAAATCAAAATAGTTTGGGTCCTTGTCGTACTGGAAGTAAC CTAGCACACAGCACACCAGTTGATATGCCAAGCAGAGGACAGAATGAAGACAGGGACAGTGGCATTGCTCGATCAGCAGCCAACAGGGAA GAGTGTCGCACCCAGGAGAAAGTTAATGCAACAGGACCACAGTTCGTGAGTGGAGTGATTGTGAAGATCATTAGCACAGAGCCTCTACCT GGCAGGAAACAAGTCCGGGATACTTTGGCAGCAATCTCAGAAGTTCTTTATGTTGATTTGCTAGAAGGGGATACAGAATGCCATGCTAGA TTTAAAACTCCTGAGGATGCTCAAGCAGTAATAAATGCCTATACAGAAATTAACAAGAAACACTGCTGGAAACTCGAGATCCTTTCTGGT GATCACGAACAAAGGTATTGGCAGAAGATTTTGGTTGATAGACAGGCAAAACTTAATCAGCCTCGGGAAAAGAAAAGAGGCACTGAAAAG |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_FNIP2_ENST00000264433_chr4_159756628_+_LARP7_ENST00000344442_chr4_113571617_+_1516nt GCGGCCGCCGCCCCCGGCTGCGCGCTGAGCCGCCGGCCCCCCGAGCGCCACGGCCGGAGCTGCGGCGGCGGCATCATGGCCCCGACCCTG CTCCAGAAGCTCTTCAACAAAAGGGGCAGCAGCGGCAGCTCCGCGGCGGCGTCTGCCCAGGGCAGGGCTCCTAAGGAAGGACCCGCCTTT AGTTGGTCATGTTCGGAGTTTGACCTGAATGAGATTCGCCTGATAGTTTACCAGGACTGTGACAGGAGAGGCAGACAAGTCTTGTTTGAC TCTAAAGCTGTTCAAAAGATTGAGGAGGTGACAGCTCAGAAAACAGAGGATGTTCCTATTAAAATATCAGCCAAGTGCTGCCAGGGAAGC AGCAGTGTCAGCAGCAGTAGCAGCAGCAGCATCTCTTCCCACAGTTCTTCTGGGGGATCTTCACATCATGCTAAGGAACAGCTTCCAAAG TACCAGTACACAAGACCAGCTTCCGATGTCAACATGTTAGGGGAAATGATGTTTGGCTCAGTTGCCATGAGTTACAAAGGCTCCACCTTA AAGATACACTACATACGTTCTCCTCCACAACTGATGATTAGTAAAGTCTTCTCTGCTAGAATGGGCAGCTTCTGTGGAAGTACAAATAAC TTGCAAGACAGCTTTGAGTACATCAACCAAGATCCTAATTTGGGAAAACTGAACACAAATCAAAATAGTTTGGGTCCTTGTCGTACTGGA AGTAACCTAGCACACAGCACACCAGTTGATATGCCAAGCAGAGGACAGAATGAAGACAGGGACAGTGGCATTGCTCGATCAGCAGCCAAC AGGGAAGAGTGTCGCACCCAGGAGAAAGTTAATGCAACAGGACCACAGTTCGTGAGTGGAGTGATTGTGAAGATCATTAGCACAGAGCCT CTACCTGGCAGGAAACAAGTCCGGGATACTTTGGCAGCAATCTCAGAAGTTCTTTATGTTGATTTGCTAGAAGGGGATACAGAATGCCAT GCTAGATTTAAAACTCCTGAGGATGCTCAAGCAGTAATAAATGCCTATACAGAAATTAACAAGAAACACTGCTGGAAACTCGAGATCCTT TCTGGTGATCACGAACAAAGGTATTGGCAGAAGATTTTGGTTGATAGACAGGCAAAACTTAATCAGCCTCGGGAAAAGAAAAGAGGCACT GAAAAGTTAATCACCAAAGCTGAAAAGATTAGACTGGCAAAGACTCAACAAGCGAGTAAACATATAAGATTTTCTGAATATGATTGAAAA AAAAAACAGTTCACCTCTTAATACTTCACAAGATACTTGAGCTGTTCTTGGGAGATTCACTTTTATTATGGTAGCACTGCATAATTAATG TGTTTTTAATTAAAAGAAATATCTTTGTTCCTCAACTTGTAAATAAGACTTTTTTCTAGAGACAAATATGATGTATACCACAATTTTTCT >In-frame_FNIP2_ENST00000264433_chr4_159756628_+_LARP7_ENST00000509061_chr4_113571617_+_1516nt GCGGCCGCCGCCCCCGGCTGCGCGCTGAGCCGCCGGCCCCCCGAGCGCCACGGCCGGAGCTGCGGCGGCGGCATCATGGCCCCGACCCTG CTCCAGAAGCTCTTCAACAAAAGGGGCAGCAGCGGCAGCTCCGCGGCGGCGTCTGCCCAGGGCAGGGCTCCTAAGGAAGGACCCGCCTTT AGTTGGTCATGTTCGGAGTTTGACCTGAATGAGATTCGCCTGATAGTTTACCAGGACTGTGACAGGAGAGGCAGACAAGTCTTGTTTGAC TCTAAAGCTGTTCAAAAGATTGAGGAGGTGACAGCTCAGAAAACAGAGGATGTTCCTATTAAAATATCAGCCAAGTGCTGCCAGGGAAGC AGCAGTGTCAGCAGCAGTAGCAGCAGCAGCATCTCTTCCCACAGTTCTTCTGGGGGATCTTCACATCATGCTAAGGAACAGCTTCCAAAG TACCAGTACACAAGACCAGCTTCCGATGTCAACATGTTAGGGGAAATGATGTTTGGCTCAGTTGCCATGAGTTACAAAGGCTCCACCTTA AAGATACACTACATACGTTCTCCTCCACAACTGATGATTAGTAAAGTCTTCTCTGCTAGAATGGGCAGCTTCTGTGGAAGTACAAATAAC TTGCAAGACAGCTTTGAGTACATCAACCAAGATCCTAATTTGGGAAAACTGAACACAAATCAAAATAGTTTGGGTCCTTGTCGTACTGGA AGTAACCTAGCACACAGCACACCAGTTGATATGCCAAGCAGAGGACAGAATGAAGACAGGGACAGTGGCATTGCTCGATCAGCAGCCAAC AGGGAAGAGTGTCGCACCCAGGAGAAAGTTAATGCAACAGGACCACAGTTCGTGAGTGGAGTGATTGTGAAGATCATTAGCACAGAGCCT CTACCTGGCAGGAAACAAGTCCGGGATACTTTGGCAGCAATCTCAGAAGTTCTTTATGTTGATTTGCTAGAAGGGGATACAGAATGCCAT GCTAGATTTAAAACTCCTGAGGATGCTCAAGCAGTAATAAATGCCTATACAGAAATTAACAAGAAACACTGCTGGAAACTCGAGATCCTT TCTGGTGATCACGAACAAAGGTATTGGCAGAAGATTTTGGTTGATAGACAGGCAAAACTTAATCAGCCTCGGGAAAAGAAAAGAGGCACT GAAAAGTTAATCACCAAAGCTGAAAAGATTAGACTGGCAAAGACTCAACAAGCGAGTAAACATATAAGATTTTCTGAATATGATTGAAAA AAAAAACAGTTCACCTCTTAATACTTCACAAGATACTTGAGCTGTTCTTGGGAGATTCACTTTTATTATGGTAGCACTGCATAATTAATG TGTTTTTAATTAAAAGAAATATCTTTGTTCCTCAACTTGTAAATAAGACTTTTTTCTAGAGACAAATATGATGTATACCACAATTTTTCT >In-frame_FNIP2_ENST00000264433_chr4_159756628_+_LARP7_ENST00000324052_chr4_113571617_+_1515nt GCGGCCGCCGCCCCCGGCTGCGCGCTGAGCCGCCGGCCCCCCGAGCGCCACGGCCGGAGCTGCGGCGGCGGCATCATGGCCCCGACCCTG CTCCAGAAGCTCTTCAACAAAAGGGGCAGCAGCGGCAGCTCCGCGGCGGCGTCTGCCCAGGGCAGGGCTCCTAAGGAAGGACCCGCCTTT AGTTGGTCATGTTCGGAGTTTGACCTGAATGAGATTCGCCTGATAGTTTACCAGGACTGTGACAGGAGAGGCAGACAAGTCTTGTTTGAC TCTAAAGCTGTTCAAAAGATTGAGGAGGTGACAGCTCAGAAAACAGAGGATGTTCCTATTAAAATATCAGCCAAGTGCTGCCAGGGAAGC AGCAGTGTCAGCAGCAGTAGCAGCAGCAGCATCTCTTCCCACAGTTCTTCTGGGGGATCTTCACATCATGCTAAGGAACAGCTTCCAAAG TACCAGTACACAAGACCAGCTTCCGATGTCAACATGTTAGGGGAAATGATGTTTGGCTCAGTTGCCATGAGTTACAAAGGCTCCACCTTA AAGATACACTACATACGTTCTCCTCCACAACTGATGATTAGTAAAGTCTTCTCTGCTAGAATGGGCAGCTTCTGTGGAAGTACAAATAAC TTGCAAGACAGCTTTGAGTACATCAACCAAGATCCTAATTTGGGAAAACTGAACACAAATCAAAATAGTTTGGGTCCTTGTCGTACTGGA AGTAACCTAGCACACAGCACACCAGTTGATATGCCAAGCAGAGGACAGAATGAAGACAGGGACAGTGGCATTGCTCGATCAGCAGCCAAC AGGGAAGAGTGTCGCACCCAGGAGAAAGTTAATGCAACAGGACCACAGTTCGTGAGTGGAGTGATTGTGAAGATCATTAGCACAGAGCCT CTACCTGGCAGGAAACAAGTCCGGGATACTTTGGCAGCAATCTCAGAAGTTCTTTATGTTGATTTGCTAGAAGGGGATACAGAATGCCAT GCTAGATTTAAAACTCCTGAGGATGCTCAAGCAGTAATAAATGCCTATACAGAAATTAACAAGAAACACTGCTGGAAACTCGAGATCCTT TCTGGTGATCACGAACAAAGGTATTGGCAGAAGATTTTGGTTGATAGACAGGCAAAACTTAATCAGCCTCGGGAAAAGAAAAGAGGCACT GAAAAGTTAATCACCAAAGCTGAAAAGATTAGACTGGCAAAGACTCAACAAGCGAGTAAACATATAAGATTTTCTGAATATGATTGAAAA AAAAAACAGTTCACCTCTTAATACTTCACAAGATACTTGAGCTGTTCTTGGGAGATTCACTTTTATTATGGTAGCACTGCATAATTAATG TGTTTTTAATTAAAAGAAATATCTTTGTTCCTCAACTTGTAAATAAGACTTTTTTCTAGAGACAAATATGATGTATACCACAATTTTTCT >In-frame_FNIP2_ENST00000379346_chr4_159756628_+_LARP7_ENST00000344442_chr4_113571617_+_1510nt ATGTGCGGCGGCACAGCGAACACCACAAACCAGCCAGAGAGCTGGCAAGACTCTGCCAGATGTGTGAGTGATGCTGTTCCTGGTGCTGGG AGGATTTACAGGGCGCTTTTATGCACAAAGATTAAAAAACACACCGGAGTAGACAGGAGCACTGACCACACGGAACTCGACAACAGTTGG TCATGTTCGGAGTTTGACCTGAATGAGATTCGCCTGATAGTTTACCAGGACTGTGACAGGAGAGGCAGACAAGTCTTGTTTGACTCTAAA GCTGTTCAAAAGATTGAGGAGGTGACAGCTCAGAAAACAGAGGATGTTCCTATTAAAATATCAGCCAAGTGCTGCCAGGGAAGCAGCAGT GTCAGCAGCAGTAGCAGCAGCAGCATCTCTTCCCACAGTTCTTCTGGGGGATCTTCACATCATGCTAAGGAACAGCTTCCAAAGTACCAG TACACAAGACCAGCTTCCGATGTCAACATGTTAGGGGAAATGATGTTTGGCTCAGTTGCCATGAGTTACAAAGGCTCCACCTTAAAGATA CACTACATACGTTCTCCTCCACAACTGATGATTAGTAAAGTCTTCTCTGCTAGAATGGGCAGCTTCTGTGGAAGTACAAATAACTTGCAA GACAGCTTTGAGTACATCAACCAAGATCCTAATTTGGGAAAACTGAACACAAATCAAAATAGTTTGGGTCCTTGTCGTACTGGAAGTAAC CTAGCACACAGCACACCAGTTGATATGCCAAGCAGAGGACAGAATGAAGACAGGGACAGTGGCATTGCTCGATCAGCAGCCAACAGGGAA GAGTGTCGCACCCAGGAGAAAGTTAATGCAACAGGACCACAGTTCGTGAGTGGAGTGATTGTGAAGATCATTAGCACAGAGCCTCTACCT GGCAGGAAACAAGTCCGGGATACTTTGGCAGCAATCTCAGAAGTTCTTTATGTTGATTTGCTAGAAGGGGATACAGAATGCCATGCTAGA TTTAAAACTCCTGAGGATGCTCAAGCAGTAATAAATGCCTATACAGAAATTAACAAGAAACACTGCTGGAAACTCGAGATCCTTTCTGGT GATCACGAACAAAGGTATTGGCAGAAGATTTTGGTTGATAGACAGGCAAAACTTAATCAGCCTCGGGAAAAGAAAAGAGGCACTGAAAAG TTAATCACCAAAGCTGAAAAGATTAGACTGGCAAAGACTCAACAAGCGAGTAAACATATAAGATTTTCTGAATATGATTGAAAAAAAAAA CAGTTCACCTCTTAATACTTCACAAGATACTTGAGCTGTTCTTGGGAGATTCACTTTTATTATGGTAGCACTGCATAATTAATGTGTTTT TAATTAAAAGAAATATCTTTGTTCCTCAACTTGTAAATAAGACTTTTTTCTAGAGACAAATATGATGTATACCACAATTTTTCTTAAACA >In-frame_FNIP2_ENST00000379346_chr4_159756628_+_LARP7_ENST00000509061_chr4_113571617_+_1510nt ATGTGCGGCGGCACAGCGAACACCACAAACCAGCCAGAGAGCTGGCAAGACTCTGCCAGATGTGTGAGTGATGCTGTTCCTGGTGCTGGG AGGATTTACAGGGCGCTTTTATGCACAAAGATTAAAAAACACACCGGAGTAGACAGGAGCACTGACCACACGGAACTCGACAACAGTTGG TCATGTTCGGAGTTTGACCTGAATGAGATTCGCCTGATAGTTTACCAGGACTGTGACAGGAGAGGCAGACAAGTCTTGTTTGACTCTAAA GCTGTTCAAAAGATTGAGGAGGTGACAGCTCAGAAAACAGAGGATGTTCCTATTAAAATATCAGCCAAGTGCTGCCAGGGAAGCAGCAGT GTCAGCAGCAGTAGCAGCAGCAGCATCTCTTCCCACAGTTCTTCTGGGGGATCTTCACATCATGCTAAGGAACAGCTTCCAAAGTACCAG TACACAAGACCAGCTTCCGATGTCAACATGTTAGGGGAAATGATGTTTGGCTCAGTTGCCATGAGTTACAAAGGCTCCACCTTAAAGATA CACTACATACGTTCTCCTCCACAACTGATGATTAGTAAAGTCTTCTCTGCTAGAATGGGCAGCTTCTGTGGAAGTACAAATAACTTGCAA GACAGCTTTGAGTACATCAACCAAGATCCTAATTTGGGAAAACTGAACACAAATCAAAATAGTTTGGGTCCTTGTCGTACTGGAAGTAAC CTAGCACACAGCACACCAGTTGATATGCCAAGCAGAGGACAGAATGAAGACAGGGACAGTGGCATTGCTCGATCAGCAGCCAACAGGGAA GAGTGTCGCACCCAGGAGAAAGTTAATGCAACAGGACCACAGTTCGTGAGTGGAGTGATTGTGAAGATCATTAGCACAGAGCCTCTACCT GGCAGGAAACAAGTCCGGGATACTTTGGCAGCAATCTCAGAAGTTCTTTATGTTGATTTGCTAGAAGGGGATACAGAATGCCATGCTAGA TTTAAAACTCCTGAGGATGCTCAAGCAGTAATAAATGCCTATACAGAAATTAACAAGAAACACTGCTGGAAACTCGAGATCCTTTCTGGT GATCACGAACAAAGGTATTGGCAGAAGATTTTGGTTGATAGACAGGCAAAACTTAATCAGCCTCGGGAAAAGAAAAGAGGCACTGAAAAG TTAATCACCAAAGCTGAAAAGATTAGACTGGCAAAGACTCAACAAGCGAGTAAACATATAAGATTTTCTGAATATGATTGAAAAAAAAAA CAGTTCACCTCTTAATACTTCACAAGATACTTGAGCTGTTCTTGGGAGATTCACTTTTATTATGGTAGCACTGCATAATTAATGTGTTTT TAATTAAAAGAAATATCTTTGTTCCTCAACTTGTAAATAAGACTTTTTTCTAGAGACAAATATGATGTATACCACAATTTTTCTTAAACA >In-frame_FNIP2_ENST00000379346_chr4_159756628_+_LARP7_ENST00000324052_chr4_113571617_+_1509nt ATGTGCGGCGGCACAGCGAACACCACAAACCAGCCAGAGAGCTGGCAAGACTCTGCCAGATGTGTGAGTGATGCTGTTCCTGGTGCTGGG AGGATTTACAGGGCGCTTTTATGCACAAAGATTAAAAAACACACCGGAGTAGACAGGAGCACTGACCACACGGAACTCGACAACAGTTGG TCATGTTCGGAGTTTGACCTGAATGAGATTCGCCTGATAGTTTACCAGGACTGTGACAGGAGAGGCAGACAAGTCTTGTTTGACTCTAAA GCTGTTCAAAAGATTGAGGAGGTGACAGCTCAGAAAACAGAGGATGTTCCTATTAAAATATCAGCCAAGTGCTGCCAGGGAAGCAGCAGT GTCAGCAGCAGTAGCAGCAGCAGCATCTCTTCCCACAGTTCTTCTGGGGGATCTTCACATCATGCTAAGGAACAGCTTCCAAAGTACCAG TACACAAGACCAGCTTCCGATGTCAACATGTTAGGGGAAATGATGTTTGGCTCAGTTGCCATGAGTTACAAAGGCTCCACCTTAAAGATA CACTACATACGTTCTCCTCCACAACTGATGATTAGTAAAGTCTTCTCTGCTAGAATGGGCAGCTTCTGTGGAAGTACAAATAACTTGCAA GACAGCTTTGAGTACATCAACCAAGATCCTAATTTGGGAAAACTGAACACAAATCAAAATAGTTTGGGTCCTTGTCGTACTGGAAGTAAC CTAGCACACAGCACACCAGTTGATATGCCAAGCAGAGGACAGAATGAAGACAGGGACAGTGGCATTGCTCGATCAGCAGCCAACAGGGAA GAGTGTCGCACCCAGGAGAAAGTTAATGCAACAGGACCACAGTTCGTGAGTGGAGTGATTGTGAAGATCATTAGCACAGAGCCTCTACCT GGCAGGAAACAAGTCCGGGATACTTTGGCAGCAATCTCAGAAGTTCTTTATGTTGATTTGCTAGAAGGGGATACAGAATGCCATGCTAGA TTTAAAACTCCTGAGGATGCTCAAGCAGTAATAAATGCCTATACAGAAATTAACAAGAAACACTGCTGGAAACTCGAGATCCTTTCTGGT GATCACGAACAAAGGTATTGGCAGAAGATTTTGGTTGATAGACAGGCAAAACTTAATCAGCCTCGGGAAAAGAAAAGAGGCACTGAAAAG TTAATCACCAAAGCTGAAAAGATTAGACTGGCAAAGACTCAACAAGCGAGTAAACATATAAGATTTTCTGAATATGATTGAAAAAAAAAA CAGTTCACCTCTTAATACTTCACAAGATACTTGAGCTGTTCTTGGGAGATTCACTTTTATTATGGTAGCACTGCATAATTAATGTGTTTT TAATTAAAAGAAATATCTTTGTTCCTCAACTTGTAAATAAGACTTTTTTCTAGAGACAAATATGATGTATACCACAATTTTTCTTAAACA |
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FusionGenePPI for FNIP2_LARP7 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| FNIP2 | FLCN, GABARAP, HSP90AA1, HSPA1B, STIP1, CDC37, PTGES3, NR3C1, CDK4, BRAF, FNIP2, FNIP1 | LARP7 | MEPCE, CDK9, HNRNPA1, TERF1, TERF2, PRPF40A, SIRT7, CAND1, APP, BARD1, PAXIP1, CSNK2A1, RPS16, RN7SK, HEXIM1, CCNT1, JMJD6, BRCC3, CD2AP, HDAC1, SPAG9, HNRNPR, HUWE1, MTA2, NR3C1, RABEP2, RPP25, TRIM28, TSC22D1, VCPIP1, LIN28A, LIN28B, AFF1, RNF2, SIRT6, HIST1H1A, NOL12, TRA2A, RPL6, NIFK, RPS2, RPSA, ZC3H3, RPS8, ZC3H8, FBL, LUC7L2, NTRK1, SSB, IFI16, MED4, ORC1, AURKA, FOXL2, HEXIM2, SART3, SNRNP70, ZCRB1, E4F1 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| Hgene | FNIP2 | chr4:159756628 | chr4:113571617 | ENST00000264433 | + | 7 | 17 | 544_911 | 242 | 1115 | PRKAA1 |
| Hgene | FNIP2 | chr4:159756628 | chr4:113571617 | ENST00000379346 | + | 7 | 17 | 544_911 | 265 | 1138 | PRKAA1 |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for FNIP2_LARP7 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for FNIP2_LARP7 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Tgene | LARP7 | C3714756 | Intellectual Disability | 1 | CTD_human |
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