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Center for Computational Systems Medicine
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FusionGeneSummary

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FusionProtFeature

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FusionGeneSequence

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FusionGenePPI

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RelatedDrugs

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RelatedDiseases

Fusion gene ID: 13706

FusionGeneSummary for FNIP2_EXOC4

check button Fusion gene summary
Fusion gene informationFusion gene name: FNIP2_EXOC4
Fusion gene ID: 13706
HgeneTgene
Gene symbol

FNIP2

EXOC4

Gene ID

57600

60412

Gene namefolliculin interacting protein 2exocyst complex component 4
SynonymsFNIPL|MAPO1SEC8|SEC8L1|Sec8p
Cytomap

4q32.1

7q33

Type of geneprotein-codingprotein-coding
Descriptionfolliculin-interacting protein 2FNIP1-like proteinO6-methylguanine-induced apoptosis 1 proteinexocyst complex component 4SEC8-like 1exocyst complex component Sec8
Modification date2018051920180523
UniProtAcc

Q9P278

Q96A65

Ensembl transtripts involved in fusion geneENST00000264433, ENST00000379346, 
ENST00000505445, 		ENST00000253861, 
ENST00000539845, ENST00000393161, 
ENST00000545148, ENST00000460346, 
ENST00000541309, 
Fusion gene scores* DoF score9 X 5 X 6=27015 X 12 X 7=1260
# samples 915
** MAII scorelog2(9/270*10)=-1.58496250072116
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(15/1260*10)=-3.0703893278914
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: FNIP2 [Title/Abstract] AND EXOC4 [Title/Abstract] AND fusion [Title/Abstract]

Functional or gene categories assigned by FusionGDB annotation
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneFNIP2

GO:0000122

negative regulation of transcription by RNA polymerase II

21209915

HgeneFNIP2

GO:0001932

regulation of protein phosphorylation

18663353

HgeneFNIP2

GO:0006468

protein phosphorylation

18663353

HgeneFNIP2

GO:0031334

positive regulation of protein complex assembly

25126726

HgeneFNIP2

GO:0033138

positive regulation of peptidyl-serine phosphorylation

19914239


check button Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
Data typeSourceCancer typeSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
TCGARVSARCTCGA-DX-A8BR-01AFNIP2chr4

159690471

+EXOC4chr7

133622644

+
* LD: Li Ding group's fusion gene list
  RV: Roel Verhaak group's fusion gene list
  ChiTaRs fusion database

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000264433ENST00000253861FNIP2chr4

159690471

+EXOC4chr7

133622644

+
In-frameENST00000264433ENST00000539845FNIP2chr4

159690471

+EXOC4chr7

133622644

+
5CDS-intronENST00000264433ENST00000393161FNIP2chr4

159690471

+EXOC4chr7

133622644

+
5CDS-intronENST00000264433ENST00000545148FNIP2chr4

159690471

+EXOC4chr7

133622644

+
5CDS-intronENST00000264433ENST00000460346FNIP2chr4

159690471

+EXOC4chr7

133622644

+
5CDS-5UTRENST00000264433ENST00000541309FNIP2chr4

159690471

+EXOC4chr7

133622644

+
intron-3CDSENST00000379346ENST00000253861FNIP2chr4

159690471

+EXOC4chr7

133622644

+
intron-3CDSENST00000379346ENST00000539845FNIP2chr4

159690471

+EXOC4chr7

133622644

+
intron-intronENST00000379346ENST00000393161FNIP2chr4

159690471

+EXOC4chr7

133622644

+
intron-intronENST00000379346ENST00000545148FNIP2chr4

159690471

+EXOC4chr7

133622644

+
intron-intronENST00000379346ENST00000460346FNIP2chr4

159690471

+EXOC4chr7

133622644

+
intron-5UTRENST00000379346ENST00000541309FNIP2chr4

159690471

+EXOC4chr7

133622644

+
intron-3CDSENST00000505445ENST00000253861FNIP2chr4

159690471

+EXOC4chr7

133622644

+
intron-3CDSENST00000505445ENST00000539845FNIP2chr4

159690471

+EXOC4chr7

133622644

+
intron-intronENST00000505445ENST00000393161FNIP2chr4

159690471

+EXOC4chr7

133622644

+
intron-intronENST00000505445ENST00000545148FNIP2chr4

159690471

+EXOC4chr7

133622644

+
intron-intronENST00000505445ENST00000460346FNIP2chr4

159690471

+EXOC4chr7

133622644

+
intron-5UTRENST00000505445ENST00000541309FNIP2chr4

159690471

+EXOC4chr7

133622644

+

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FusionProtFeatures for FNIP2_EXOC4


check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
FNIP2

Q9P278

EXOC4

Q96A65

Acts as a co-chaperone of HSP90AA1. Inhibits the ATPaseactivity of HSP90AA1 leading to reduction in its chaperoneactivity. Facilitates the binding of client protein FLCN toHSP90AA1 (PubMed:27353360). May play a role in the signaltransduction pathway of apoptosis induced by O6-methylguanine-mispaired lesions (By similarity). May be involved in energyand/or nutrient sensing through the AMPK and mTOR signalingpathways (PubMed:18403135). May regulate phosphorylation ofRPS6KB1 (PubMed:18663353). {ECO:0000250|UniProtKB:Q80TD3,ECO:0000269|PubMed:18403135, ECO:0000269|PubMed:18663353,ECO:0000269|PubMed:27353360}. Component of the exocyst complex involved in the dockingof exocytic vesicles with fusion sites on the plasma membrane.{ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

.

* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneEXOC4chr4:159690471chr7:133622644ENST00000393161+01032_114-10474Coiled coilOntology_term=ECO:0000255

- In-frame and not-retained protein feature among the 13 regional features.
>>>>>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneFNIP2chr4:159690471chr7:133622644ENST00000264433+117242_265351115Compositional biasNote=Ser-rich
HgeneFNIP2chr4:159690471chr7:133622644ENST00000264433+11795_116351115Compositional biasNote=Ser-rich
HgeneFNIP2chr4:159690471chr7:133622644ENST00000379346+117242_26501138Compositional biasNote=Ser-rich
HgeneFNIP2chr4:159690471chr7:133622644ENST00000379346+11795_11601138Compositional biasNote=Ser-rich
HgeneFNIP2chr4:159690471chr7:133622644ENST00000264433+1171050_1105351115DomaindDENN FNIP1/2-type
HgeneFNIP2chr4:159690471chr7:133622644ENST00000264433+11742_460351115DomainuDENN FNIP1/2-type
HgeneFNIP2chr4:159690471chr7:133622644ENST00000264433+117468_1040351115DomaincDENN FNIP1/2-type
HgeneFNIP2chr4:159690471chr7:133622644ENST00000379346+1171050_110501138DomaindDENN FNIP1/2-type
HgeneFNIP2chr4:159690471chr7:133622644ENST00000379346+11742_46001138DomainuDENN FNIP1/2-type
HgeneFNIP2chr4:159690471chr7:133622644ENST00000379346+117468_104001138DomaincDENN FNIP1/2-type
TgeneEXOC4chr4:159690471chr7:133622644ENST00000253861+121832_114675975Coiled coilOntology_term=ECO:0000255


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FusionGeneSequence for FNIP2_EXOC4


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.
>In-frame_FNIP2_ENST00000264433_chr4_159690471_+_EXOC4_ENST00000253861_chr7_133622644_+_335aa
MAPTLLQKLFNKRGSSGSSAAASAQGRAPKEGPAFRAAFGKESEVLIGNLGDKLIPPQDILRDVSDLKALANMHESLEWLASRTKSAFSN
LSTSQMLSPAQDSHTNTDLPPVSEQIMQTLSELAKSFQDMADRCLLVLHLEVRVHCFHYLIPLAKEGNYAIVANVESMDYDPLVVKLNKD
ISAIEEAMSASLQQHKFQYIFEGLGHLISCILINGAQYFRRISESGIKKMCRNIFVLQQNLTNITMSREADLDFARQYYEMLYNTADELL

>In-frame_FNIP2_ENST00000264433_chr4_159690471_+_EXOC4_ENST00000539845_chr7_133622644_+_335aa
MAPTLLQKLFNKRGSSGSSAAASAQGRAPKEGPAFRAAFGKESEVLIGNLGDKLIPPQDILRDVSDLKALANMHESLEWLASRTKSAFSN
LSTSQMLSPAQDSHTNTDLPPVSEQIMQTLSELAKSFQDMADRCLLVLHLEVRVHCFHYLIPLAKEGNYAIVANVESMDYDPLVVKLNKD
ISAIEEAMSASLQQHKFQYIFEGLGHLISCILINGAQYFRRISESGIKKMCRNIFVLQQNLTNITMSREADLDFARQYYEMLYNTADELL


* Fusion transcript sequences (only coding sequence (CDS) region).
>In-frame_FNIP2_ENST00000264433_chr4_159690471_+_EXOC4_ENST00000253861_chr7_133622644_+_1005nt
ATGGCCCCGACCCTGCTCCAGAAGCTCTTCAACAAAAGGGGCAGCAGCGGCAGCTCCGCGGCGGCGTCTGCCCAGGGCAGGGCTCCTAAG
GAAGGACCCGCCTTTAGGGCAGCTTTTGGCAAGGAGTCTGAAGTTCTTATTGGGAACCTGGGTGATAAATTAATCCCTCCACAAGACATC
CTTCGTGACGTCAGTGACCTCAAAGCCTTGGCCAACATGCATGAAAGCCTGGAATGGTTGGCAAGTCGAACAAAGTCAGCTTTCTCCAAT
CTTTCTACATCCCAGATGCTTTCTCCTGCTCAAGACAGCCACACGAACACGGATCTCCCCCCAGTGTCAGAGCAGATCATGCAGACTCTC
AGTGAACTTGCCAAATCGTTCCAGGATATGGCTGACCGCTGCTTGCTTGTCTTACATCTGGAAGTGAGGGTTCACTGTTTCCACTATCTT
ATCCCTCTTGCAAAGGAGGGGAACTATGCCATTGTGGCTAATGTGGAAAGTATGGATTATGACCCCCTGGTGGTCAAGCTCAACAAAGAT
ATCAGCGCCATTGAAGAGGCCATGAGCGCCAGCCTTCAGCAGCACAAGTTCCAGTATATCTTCGAAGGCCTGGGCCACCTGATCTCCTGC
ATCCTCATTAATGGTGCCCAGTACTTCAGGCGCATCAGTGAGTCTGGCATCAAGAAAATGTGTAGGAACATTTTTGTTCTTCAGCAGAAT
TTGACCAACATCACCATGTCGCGGGAGGCAGACCTGGACTTTGCAAGGCAGTACTACGAGATGCTTTACAACACAGCTGACGAGCTCCTG
AACCTGGTGGTGGACCAGGGTGTGAAGTACACGGAGCTGGAGTACATCCACGCTCTGACCCTGCTGCACCGCAGCCAGACTGGGGTGGGG
GAACTGACCACCCAGAACACGAGGCTGCAGAGGCTCAAAGAGATCATCTGCGAGCAGGCTGCCATCAAGCAAGCCACCAAGGACAAGAAG

>In-frame_FNIP2_ENST00000264433_chr4_159690471_+_EXOC4_ENST00000539845_chr7_133622644_+_1005nt
ATGGCCCCGACCCTGCTCCAGAAGCTCTTCAACAAAAGGGGCAGCAGCGGCAGCTCCGCGGCGGCGTCTGCCCAGGGCAGGGCTCCTAAG
GAAGGACCCGCCTTTAGGGCAGCTTTTGGCAAGGAGTCTGAAGTTCTTATTGGGAACCTGGGTGATAAATTAATCCCTCCACAAGACATC
CTTCGTGACGTCAGTGACCTCAAAGCCTTGGCCAACATGCATGAAAGCCTGGAATGGTTGGCAAGTCGAACAAAGTCAGCTTTCTCCAAT
CTTTCTACATCCCAGATGCTTTCTCCTGCTCAAGACAGCCACACGAACACGGATCTCCCCCCAGTGTCAGAGCAGATCATGCAGACTCTC
AGTGAACTTGCCAAATCGTTCCAGGATATGGCTGACCGCTGCTTGCTTGTCTTACATCTGGAAGTGAGGGTTCACTGTTTCCACTATCTT
ATCCCTCTTGCAAAGGAGGGGAACTATGCCATTGTGGCTAATGTGGAAAGTATGGATTATGACCCCCTGGTGGTCAAGCTCAACAAAGAT
ATCAGCGCCATTGAAGAGGCCATGAGCGCCAGCCTTCAGCAGCACAAGTTCCAGTATATCTTCGAAGGCCTGGGCCACCTGATCTCCTGC
ATCCTCATTAATGGTGCCCAGTACTTCAGGCGCATCAGTGAGTCTGGCATCAAGAAAATGTGTAGGAACATTTTTGTTCTTCAGCAGAAT
TTGACCAACATCACCATGTCGCGGGAGGCAGACCTGGACTTTGCAAGGCAGTACTACGAGATGCTTTACAACACAGCTGACGAGCTCCTG
AACCTGGTGGTGGACCAGGGTGTGAAGTACACGGAGCTGGAGTACATCCACGCTCTGACCCTGCTGCACCGCAGCCAGACTGGGGTGGGG
GAACTGACCACCCAGAACACGAGGCTGCAGAGGCTCAAAGAGATCATCTGCGAGCAGGCTGCCATCAAGCAAGCCACCAAGGACAAGAAG


* Fusion transcript sequences (Full-length transcript).
>In-frame_FNIP2_ENST00000264433_chr4_159690471_+_EXOC4_ENST00000253861_chr7_133622644_+_2311nt
GCGGCCGCCGCCCCCGGCTGCGCGCTGAGCCGCCGGCCCCCCGAGCGCCACGGCCGGAGCTGCGGCGGCGGCATCATGGCCCCGACCCTG
CTCCAGAAGCTCTTCAACAAAAGGGGCAGCAGCGGCAGCTCCGCGGCGGCGTCTGCCCAGGGCAGGGCTCCTAAGGAAGGACCCGCCTTT
AGGGCAGCTTTTGGCAAGGAGTCTGAAGTTCTTATTGGGAACCTGGGTGATAAATTAATCCCTCCACAAGACATCCTTCGTGACGTCAGT
GACCTCAAAGCCTTGGCCAACATGCATGAAAGCCTGGAATGGTTGGCAAGTCGAACAAAGTCAGCTTTCTCCAATCTTTCTACATCCCAG
ATGCTTTCTCCTGCTCAAGACAGCCACACGAACACGGATCTCCCCCCAGTGTCAGAGCAGATCATGCAGACTCTCAGTGAACTTGCCAAA
TCGTTCCAGGATATGGCTGACCGCTGCTTGCTTGTCTTACATCTGGAAGTGAGGGTTCACTGTTTCCACTATCTTATCCCTCTTGCAAAG
GAGGGGAACTATGCCATTGTGGCTAATGTGGAAAGTATGGATTATGACCCCCTGGTGGTCAAGCTCAACAAAGATATCAGCGCCATTGAA
GAGGCCATGAGCGCCAGCCTTCAGCAGCACAAGTTCCAGTATATCTTCGAAGGCCTGGGCCACCTGATCTCCTGCATCCTCATTAATGGT
GCCCAGTACTTCAGGCGCATCAGTGAGTCTGGCATCAAGAAAATGTGTAGGAACATTTTTGTTCTTCAGCAGAATTTGACCAACATCACC
ATGTCGCGGGAGGCAGACCTGGACTTTGCAAGGCAGTACTACGAGATGCTTTACAACACAGCTGACGAGCTCCTGAACCTGGTGGTGGAC
CAGGGTGTGAAGTACACGGAGCTGGAGTACATCCACGCTCTGACCCTGCTGCACCGCAGCCAGACTGGGGTGGGGGAACTGACCACCCAG
AACACGAGGCTGCAGAGGCTCAAAGAGATCATCTGCGAGCAGGCTGCCATCAAGCAAGCCACCAAGGACAAGAAGATAACTACCGTTTAG
CAGGGCGTACTGCGGTTGGTGACGGGGGTCCCCTCAGTCACACTCACTTTTTTCCTTGGTATGTTATTGAGTATATTCTGAGCTTAGTTT
TCTCTACAGTGATACTTTAGTGGAGAGGAGGTGTAAGGATTCTTTCTCTCTGGTTTTGGCTTTTCATATAAATGCTAAAGGAAGGCGACA
GTACAGAGTGTTTTGGTTGAACAACTACTTTAATGCAGTCAAATCTAACGGGACTAGGGTGGGATAGGGAGGAAGGTGGTATCAAATTGT
TGGACTCTGAAAAACAAGTGGATGGATTACTAATATTTGATTTATTACTCAATATATATATAATTCCAGCCTTGGAAAGTAGGAAAGTAG
GCTGCTACCTAACTTTTAGTCCCTTCCAAAACCATTTAGTAGGGTTCTATTACATAAACAGTAGGGTTTTTCCTCTCCTGACCTTATCCG
TTTACAGTTCAATGAAATAAGTGTATGTGCATTGCTGTCTGTCTCTATTGCCAAAATCAAATAAATGGCTTCTCAGCTGCTGTTTACAAC
AAACTTCCCTAACCAAAACAGAACCTCTAATTTAGGGCTAGGAATAGAAGTCTTTTGATCCCAGTCCCTGGGACAGTTTTGTATGCTGTA
TCTTGTACACAGGTTGTAGGTTGGTTTATTGCCATTTTGTTTTATTTCTGCTGTATAAAAACCAAGAGCCAGACAATTAGACAACTATGG
AGGAATGAAAGGCAATTCAAACATCTGCTTGATTCCCGCCCCGCCACCCCTAATTTCTGAGAGAATAATGGTTAGAGAACATTGCATCTC
ACTTGAAACATCCTTTGGGGGTAAATGATTCTTAGGTGCTCACTTGGTCTGAGCTCAGCTGAATGCAGGGAAGATGGGACAGAGTGACAT
TTCTCCTCTGTGCGGCCTCCAGCTGAGCCTGTCTCTGAATTGTTCCCTCCCCCGCAATGTGGGCACTTACCATGTTCCTGGCACACTGGA
CCTCACCATGTCCCCCGGTCACCAGTCCTCTTGCTGCCCATGGTTCATAGGTCATAGAAGGCAGCAATGCACTGACTGGGCCACATCTTG
AAAACTCGTGGAAAGGGAAAGGGGAGGAGATGGGACTTTGACCACACACAGTGATGCCTCACACCCTGAAGGTGGGGGATTTTGTACCTG

>In-frame_FNIP2_ENST00000264433_chr4_159690471_+_EXOC4_ENST00000539845_chr7_133622644_+_1139nt
GCGGCCGCCGCCCCCGGCTGCGCGCTGAGCCGCCGGCCCCCCGAGCGCCACGGCCGGAGCTGCGGCGGCGGCATCATGGCCCCGACCCTG
CTCCAGAAGCTCTTCAACAAAAGGGGCAGCAGCGGCAGCTCCGCGGCGGCGTCTGCCCAGGGCAGGGCTCCTAAGGAAGGACCCGCCTTT
AGGGCAGCTTTTGGCAAGGAGTCTGAAGTTCTTATTGGGAACCTGGGTGATAAATTAATCCCTCCACAAGACATCCTTCGTGACGTCAGT
GACCTCAAAGCCTTGGCCAACATGCATGAAAGCCTGGAATGGTTGGCAAGTCGAACAAAGTCAGCTTTCTCCAATCTTTCTACATCCCAG
ATGCTTTCTCCTGCTCAAGACAGCCACACGAACACGGATCTCCCCCCAGTGTCAGAGCAGATCATGCAGACTCTCAGTGAACTTGCCAAA
TCGTTCCAGGATATGGCTGACCGCTGCTTGCTTGTCTTACATCTGGAAGTGAGGGTTCACTGTTTCCACTATCTTATCCCTCTTGCAAAG
GAGGGGAACTATGCCATTGTGGCTAATGTGGAAAGTATGGATTATGACCCCCTGGTGGTCAAGCTCAACAAAGATATCAGCGCCATTGAA
GAGGCCATGAGCGCCAGCCTTCAGCAGCACAAGTTCCAGTATATCTTCGAAGGCCTGGGCCACCTGATCTCCTGCATCCTCATTAATGGT
GCCCAGTACTTCAGGCGCATCAGTGAGTCTGGCATCAAGAAAATGTGTAGGAACATTTTTGTTCTTCAGCAGAATTTGACCAACATCACC
ATGTCGCGGGAGGCAGACCTGGACTTTGCAAGGCAGTACTACGAGATGCTTTACAACACAGCTGACGAGCTCCTGAACCTGGTGGTGGAC
CAGGGTGTGAAGTACACGGAGCTGGAGTACATCCACGCTCTGACCCTGCTGCACCGCAGCCAGACTGGGGTGGGGGAACTGACCACCCAG
AACACGAGGCTGCAGAGGCTCAAAGAGATCATCTGCGAGCAGGCTGCCATCAAGCAAGCCACCAAGGACAAGAAGATAACTACCGTTTAG


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FusionGenePPI for FNIP2_EXOC4


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page

.

check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors
FNIP2FLCN, GABARAP, HSP90AA1, HSPA1B, STIP1, CDC37, PTGES3, NR3C1, CDK4, BRAF, FNIP2, FNIP1EXOC4MYC, DLG3, EXOC3, GRIN2B, DLG4, EXOC7, GTF2E2, DISC1, DTNBP1, CEP63, EXOC1, MYO5A, EXOC2, EXOC8, EXOC5, IQCB1, EGFR, ATG5, ATG12, BECN1, SNAP29, BSG, TPM1, SETDB1, EXOC6, NTRK1, MED4, SCLT1, OFD1, PCM1, CNTROB, FGFR1OP, CEP128, CEP44, CNTRL, ODF2, DYNLT1, TMEM17, SNW1, CDC5L, PTAR1, MTMR4, STX11, IKBIP, IL1R2, GGA1, APLNR, EXOC3L2, EXOC6B, TSSC1, RABEP2, VPS51, RABEP1, RALB, TRIM25


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
HgeneFNIP2chr4:159690471chr7:133622644ENST00000264433+117544_911351115PRKAA1
HgeneFNIP2chr4:159690471chr7:133622644ENST00000379346+117544_91101138PRKAA1


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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RelatedDrugs for FNIP2_EXOC4


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for FNIP2_EXOC4


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource