FusionGDB Logo

Home

Download

Statistics

Examples

Help

Contact
Center for Computational Systems Medicine
leaf

FusionGeneSummary

leaf

FusionProtFeature

leaf

FusionGeneSequence

leaf

FusionGenePPI

leaf

RelatedDrugs

leaf

RelatedDiseases

Fusion gene ID: 1350

FusionGeneSummary for AKAP8L_EPS15L1

check button Fusion gene summary
Fusion gene informationFusion gene name: AKAP8L_EPS15L1
Fusion gene ID: 1350
HgeneTgene
Gene symbol

AKAP8L

EPS15L1

Gene ID

26993

58513

Gene nameA-kinase anchoring protein 8 likeepidermal growth factor receptor pathway substrate 15 like 1
SynonymsHA95|HAP95|NAKAP|NAKAP95EPS15R
Cytomap

19p13.12

19p13.11

Type of geneprotein-codingprotein-coding
DescriptionA-kinase anchor protein 8-likeA kinase (PRKA) anchor protein 8-likeAKAP8-like proteinhelicase A-binding protein 95 kDahomologous to AKAP95 proteinneighbor of A-kinase anchoring protein 95neighbor of AKAP95testis tissue sperm-binding protein Li 90mPepidermal growth factor receptor substrate 15-like 1epidermal growth factor receptor substrate EPS15Reps15-related protein
Modification date2018052320180522
UniProtAcc

Q9ULX6

Q9UBC2

Ensembl transtripts involved in fusion geneENST00000397410, ENST00000595465, 
ENST00000595879, 		ENST00000455140, 
ENST00000248070, ENST00000535753, 
ENST00000594975, ENST00000602009, 
ENST00000597937, 
Fusion gene scores* DoF score6 X 5 X 4=12010 X 8 X 5=400
# samples 69
** MAII scorelog2(6/120*10)=-1
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(9/400*10)=-2.15200309344505
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: AKAP8L [Title/Abstract] AND EPS15L1 [Title/Abstract] AND fusion [Title/Abstract]

Functional or gene categories assigned by FusionGDB annotation
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneAKAP8L

GO:0006397

mRNA processing

17594903

HgeneAKAP8L

GO:0010793

regulation of mRNA export from nucleus

11402034

HgeneAKAP8L

GO:0045944

positive regulation of transcription by RNA polymerase II

11884601


check button Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
Data typeSourceCancer typeSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
TCGALDSARCTCGA-DX-A1L2-01AAKAP8Lchr19

15529722

-EPS15L1chr19

16532287

-
* LD: Li Ding group's fusion gene list
  RV: Roel Verhaak group's fusion gene list
  ChiTaRs fusion database

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000397410ENST00000455140AKAP8Lchr19

15529722

-EPS15L1chr19

16532287

-
In-frameENST00000397410ENST00000248070AKAP8Lchr19

15529722

-EPS15L1chr19

16532287

-
In-frameENST00000397410ENST00000535753AKAP8Lchr19

15529722

-EPS15L1chr19

16532287

-
In-frameENST00000397410ENST00000594975AKAP8Lchr19

15529722

-EPS15L1chr19

16532287

-
In-frameENST00000397410ENST00000602009AKAP8Lchr19

15529722

-EPS15L1chr19

16532287

-
In-frameENST00000397410ENST00000597937AKAP8Lchr19

15529722

-EPS15L1chr19

16532287

-
In-frameENST00000595465ENST00000455140AKAP8Lchr19

15529722

-EPS15L1chr19

16532287

-
In-frameENST00000595465ENST00000248070AKAP8Lchr19

15529722

-EPS15L1chr19

16532287

-
In-frameENST00000595465ENST00000535753AKAP8Lchr19

15529722

-EPS15L1chr19

16532287

-
In-frameENST00000595465ENST00000594975AKAP8Lchr19

15529722

-EPS15L1chr19

16532287

-
In-frameENST00000595465ENST00000602009AKAP8Lchr19

15529722

-EPS15L1chr19

16532287

-
In-frameENST00000595465ENST00000597937AKAP8Lchr19

15529722

-EPS15L1chr19

16532287

-
intron-3CDSENST00000595879ENST00000455140AKAP8Lchr19

15529722

-EPS15L1chr19

16532287

-
intron-3CDSENST00000595879ENST00000248070AKAP8Lchr19

15529722

-EPS15L1chr19

16532287

-
intron-3CDSENST00000595879ENST00000535753AKAP8Lchr19

15529722

-EPS15L1chr19

16532287

-
intron-3CDSENST00000595879ENST00000594975AKAP8Lchr19

15529722

-EPS15L1chr19

16532287

-
intron-3CDSENST00000595879ENST00000602009AKAP8Lchr19

15529722

-EPS15L1chr19

16532287

-
intron-3CDSENST00000595879ENST00000597937AKAP8Lchr19

15529722

-EPS15L1chr19

16532287

-

Top

FusionProtFeatures for AKAP8L_EPS15L1


check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
AKAP8L

Q9ULX6

EPS15L1

Q9UBC2

Could play a role in constitutive transport element(CTE)-mediated gene expression by association with DHX9. IncreasesCTE-dependent nuclear unspliced mRNA export (PubMed:10748171,PubMed:11402034). Proposed to target PRKACA to the nucleus butdoes not seem to be implicated in the binding of regulatorysubunit II of PKA (PubMed:10761695, PubMed:11884601). May beinvolved in nuclear envelope breakdown and chromatin condensation.May be involved in anchoring nuclear membranes to chromatin ininterphase and in releasing membranes from chromating at mitosis(PubMed:11034899). May regulate the initiation phase of DNAreplication when associated with TMPO isoform Beta(PubMed:12538639). Required for cell cycle G2/M transition andhistone deacetylation during mitosis. In mitotic cells recruitsHDAC3 to the vicinity of chromatin leading to deacetylation andsubsequent phosphorylation at 'Ser-10' of histone H3; in thisfunction seems to act redundantly with AKAP8 (PubMed:16980585).May be involved in regulation of pre-mRNA splicing(PubMed:17594903). {ECO:0000269|PubMed:10748171,ECO:0000269|PubMed:11034899, ECO:0000269|PubMed:11402034,ECO:0000269|PubMed:11884601, ECO:0000269|PubMed:12538639,ECO:0000269|PubMed:16980585, ECO:0000305|PubMed:10761695}. (Microbial infection) In case of EBV infection, maytarget PRKACA to EBNA-LP-containing nuclear sites to modulatetranscription from specific promoters.{ECO:0000269|PubMed:11884601}. (Microbial infection) Can synergize with DHX9 toactivate the CTE-mediated gene expression of type D retroviruses.{ECO:0000269|PubMed:11402034}. (Microbial infection) In case of HIV-1 infection,involved in the DHX9-promoted annealing of host tRNA(Lys3) toviral genomic RNA as a primer in reverse transcription; in vitronegatively regulates DHX9 annealing activity.{ECO:0000269|PubMed:25034436}. Seems to be a constitutive component of clathrin-coatedpits that is required for receptor-mediated endocytosis. Involvedin endocytosis of integrin beta-1 (ITGB1) and transferrin receptor(TFR); internalization of ITGB1 as DAB2-dependent cargo but notTFR seems to require association with DAB2.{ECO:0000269|PubMed:22648170, ECO:0000269|PubMed:9407958}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

.

* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneEPS15L1chr19:15529722chr19:16532287ENST00000248070-823386_553264865Coiled coilOntology_term=ECO:0000255
TgeneEPS15L1chr19:15529722chr19:16532287ENST00000455140-824386_553264911Coiled coilOntology_term=ECO:0000255
TgeneEPS15L1chr19:15529722chr19:16532287ENST00000535753-822386_553264755Coiled coilOntology_term=ECO:0000255
TgeneEPS15L1chr19:15529722chr19:16532287ENST00000597937-816386_553264602Coiled coilOntology_term=ECO:0000255
TgeneEPS15L1chr19:15529722chr19:16532287ENST00000248070-823750_816264865Compositional biasNote=Pro-rich
TgeneEPS15L1chr19:15529722chr19:16532287ENST00000455140-824750_816264911Compositional biasNote=Pro-rich
TgeneEPS15L1chr19:15529722chr19:16532287ENST00000535753-822750_816264755Compositional biasNote=Pro-rich
TgeneEPS15L1chr19:15529722chr19:16532287ENST00000597937-816750_816264602Compositional biasNote=Pro-rich
TgeneEPS15L1chr19:15529722chr19:16532287ENST00000248070-823275_365264865DomainEH 3
TgeneEPS15L1chr19:15529722chr19:16532287ENST00000455140-824275_365264911DomainEH 3
TgeneEPS15L1chr19:15529722chr19:16532287ENST00000535753-822275_365264755DomainEH 3
TgeneEPS15L1chr19:15529722chr19:16532287ENST00000597937-816275_365264602DomainEH 3
TgeneEPS15L1chr19:15529722chr19:16532287ENST00000248070-823618_835264865RegionNote=15 X 3 AA repeats of D-P-F
TgeneEPS15L1chr19:15529722chr19:16532287ENST00000455140-824618_835264911RegionNote=15 X 3 AA repeats of D-P-F
TgeneEPS15L1chr19:15529722chr19:16532287ENST00000535753-822618_835264755RegionNote=15 X 3 AA repeats of D-P-F
TgeneEPS15L1chr19:15529722chr19:16532287ENST00000597937-816618_835264602RegionNote=15 X 3 AA repeats of D-P-F
TgeneEPS15L1chr19:15529722chr19:16532287ENST00000248070-823618_620264865RepeatNote=1
TgeneEPS15L1chr19:15529722chr19:16532287ENST00000248070-823640_642264865RepeatNote=2
TgeneEPS15L1chr19:15529722chr19:16532287ENST00000248070-823645_647264865RepeatNote=3
TgeneEPS15L1chr19:15529722chr19:16532287ENST00000248070-823650_652264865RepeatNote=4
TgeneEPS15L1chr19:15529722chr19:16532287ENST00000248070-823656_658264865RepeatNote=5
TgeneEPS15L1chr19:15529722chr19:16532287ENST00000248070-823661_663264865RepeatNote=6
TgeneEPS15L1chr19:15529722chr19:16532287ENST00000248070-823667_669264865RepeatNote=7
TgeneEPS15L1chr19:15529722chr19:16532287ENST00000248070-823685_687264865RepeatNote=8
TgeneEPS15L1chr19:15529722chr19:16532287ENST00000248070-823690_692264865RepeatNote=9
TgeneEPS15L1chr19:15529722chr19:16532287ENST00000248070-823709_711264865RepeatNote=10
TgeneEPS15L1chr19:15529722chr19:16532287ENST00000248070-823728_730264865RepeatNote=11
TgeneEPS15L1chr19:15529722chr19:16532287ENST00000248070-823754_756264865RepeatNote=12
TgeneEPS15L1chr19:15529722chr19:16532287ENST00000248070-823806_808264865RepeatNote=13
TgeneEPS15L1chr19:15529722chr19:16532287ENST00000248070-823812_814264865RepeatNote=14
TgeneEPS15L1chr19:15529722chr19:16532287ENST00000248070-823833_835264865RepeatNote=15
TgeneEPS15L1chr19:15529722chr19:16532287ENST00000455140-824618_620264911RepeatNote=1
TgeneEPS15L1chr19:15529722chr19:16532287ENST00000455140-824640_642264911RepeatNote=2
TgeneEPS15L1chr19:15529722chr19:16532287ENST00000455140-824645_647264911RepeatNote=3
TgeneEPS15L1chr19:15529722chr19:16532287ENST00000455140-824650_652264911RepeatNote=4
TgeneEPS15L1chr19:15529722chr19:16532287ENST00000455140-824656_658264911RepeatNote=5
TgeneEPS15L1chr19:15529722chr19:16532287ENST00000455140-824661_663264911RepeatNote=6
TgeneEPS15L1chr19:15529722chr19:16532287ENST00000455140-824667_669264911RepeatNote=7
TgeneEPS15L1chr19:15529722chr19:16532287ENST00000455140-824685_687264911RepeatNote=8
TgeneEPS15L1chr19:15529722chr19:16532287ENST00000455140-824690_692264911RepeatNote=9
TgeneEPS15L1chr19:15529722chr19:16532287ENST00000455140-824709_711264911RepeatNote=10
TgeneEPS15L1chr19:15529722chr19:16532287ENST00000455140-824728_730264911RepeatNote=11
TgeneEPS15L1chr19:15529722chr19:16532287ENST00000455140-824754_756264911RepeatNote=12
TgeneEPS15L1chr19:15529722chr19:16532287ENST00000455140-824806_808264911RepeatNote=13
TgeneEPS15L1chr19:15529722chr19:16532287ENST00000455140-824812_814264911RepeatNote=14
TgeneEPS15L1chr19:15529722chr19:16532287ENST00000455140-824833_835264911RepeatNote=15
TgeneEPS15L1chr19:15529722chr19:16532287ENST00000535753-822618_620264755RepeatNote=1
TgeneEPS15L1chr19:15529722chr19:16532287ENST00000535753-822640_642264755RepeatNote=2
TgeneEPS15L1chr19:15529722chr19:16532287ENST00000535753-822645_647264755RepeatNote=3
TgeneEPS15L1chr19:15529722chr19:16532287ENST00000535753-822650_652264755RepeatNote=4
TgeneEPS15L1chr19:15529722chr19:16532287ENST00000535753-822656_658264755RepeatNote=5
TgeneEPS15L1chr19:15529722chr19:16532287ENST00000535753-822661_663264755RepeatNote=6
TgeneEPS15L1chr19:15529722chr19:16532287ENST00000535753-822667_669264755RepeatNote=7
TgeneEPS15L1chr19:15529722chr19:16532287ENST00000535753-822685_687264755RepeatNote=8
TgeneEPS15L1chr19:15529722chr19:16532287ENST00000535753-822690_692264755RepeatNote=9
TgeneEPS15L1chr19:15529722chr19:16532287ENST00000535753-822709_711264755RepeatNote=10
TgeneEPS15L1chr19:15529722chr19:16532287ENST00000535753-822728_730264755RepeatNote=11
TgeneEPS15L1chr19:15529722chr19:16532287ENST00000535753-822754_756264755RepeatNote=12
TgeneEPS15L1chr19:15529722chr19:16532287ENST00000535753-822806_808264755RepeatNote=13
TgeneEPS15L1chr19:15529722chr19:16532287ENST00000535753-822812_814264755RepeatNote=14
TgeneEPS15L1chr19:15529722chr19:16532287ENST00000535753-822833_835264755RepeatNote=15
TgeneEPS15L1chr19:15529722chr19:16532287ENST00000597937-816618_620264602RepeatNote=1
TgeneEPS15L1chr19:15529722chr19:16532287ENST00000597937-816640_642264602RepeatNote=2
TgeneEPS15L1chr19:15529722chr19:16532287ENST00000597937-816645_647264602RepeatNote=3
TgeneEPS15L1chr19:15529722chr19:16532287ENST00000597937-816650_652264602RepeatNote=4
TgeneEPS15L1chr19:15529722chr19:16532287ENST00000597937-816656_658264602RepeatNote=5
TgeneEPS15L1chr19:15529722chr19:16532287ENST00000597937-816661_663264602RepeatNote=6
TgeneEPS15L1chr19:15529722chr19:16532287ENST00000597937-816667_669264602RepeatNote=7
TgeneEPS15L1chr19:15529722chr19:16532287ENST00000597937-816685_687264602RepeatNote=8
TgeneEPS15L1chr19:15529722chr19:16532287ENST00000597937-816690_692264602RepeatNote=9
TgeneEPS15L1chr19:15529722chr19:16532287ENST00000597937-816709_711264602RepeatNote=10
TgeneEPS15L1chr19:15529722chr19:16532287ENST00000597937-816728_730264602RepeatNote=11
TgeneEPS15L1chr19:15529722chr19:16532287ENST00000597937-816754_756264602RepeatNote=12
TgeneEPS15L1chr19:15529722chr19:16532287ENST00000597937-816806_808264602RepeatNote=13
TgeneEPS15L1chr19:15529722chr19:16532287ENST00000597937-816812_814264602RepeatNote=14
TgeneEPS15L1chr19:15529722chr19:16532287ENST00000597937-816833_835264602RepeatNote=15

- In-frame and not-retained protein feature among the 13 regional features.
>>>>>>>>>>>>>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneAKAP8Lchr19:15529722chr19:16532287ENST00000397410-11441_524647Compositional biasNote=Gly/Tyr-rich
HgeneAKAP8Lchr19:15529722chr19:16532287ENST00000397410-114589_5974647Compositional biasNote=Pro-rich
HgeneAKAP8Lchr19:15529722chr19:16532287ENST00000397410-114602_6084647Compositional biasNote=Pro-rich
HgeneAKAP8Lchr19:15529722chr19:16532287ENST00000595465-11441_524586Compositional biasNote=Gly/Tyr-rich
HgeneAKAP8Lchr19:15529722chr19:16532287ENST00000595465-114589_5974586Compositional biasNote=Pro-rich
HgeneAKAP8Lchr19:15529722chr19:16532287ENST00000595465-114602_6084586Compositional biasNote=Pro-rich
HgeneAKAP8Lchr19:15529722chr19:16532287ENST00000397410-114274_2794647MotifNuclear localization signal
HgeneAKAP8Lchr19:15529722chr19:16532287ENST00000397410-114280_2964647MotifNuclear export signal (NES)
HgeneAKAP8Lchr19:15529722chr19:16532287ENST00000397410-114362_3644647MotifNuclear localization signal
HgeneAKAP8Lchr19:15529722chr19:16532287ENST00000595465-114274_2794586MotifNuclear localization signal
HgeneAKAP8Lchr19:15529722chr19:16532287ENST00000595465-114280_2964586MotifNuclear export signal (NES)
HgeneAKAP8Lchr19:15529722chr19:16532287ENST00000595465-114362_3644586MotifNuclear localization signal
HgeneAKAP8Lchr19:15529722chr19:16532287ENST00000397410-1141_2684647RegionSufficient for activation of CTE-mediated expression
HgeneAKAP8Lchr19:15529722chr19:16532287ENST00000595465-1141_2684586RegionSufficient for activation of CTE-mediated expression
HgeneAKAP8Lchr19:15529722chr19:16532287ENST00000397410-114391_4134647Zinc fingerC2H2 AKAP95-type 1
HgeneAKAP8Lchr19:15529722chr19:16532287ENST00000397410-114484_5074647Zinc fingerC2H2 AKAP95-type 2
HgeneAKAP8Lchr19:15529722chr19:16532287ENST00000595465-114391_4134586Zinc fingerC2H2 AKAP95-type 1
HgeneAKAP8Lchr19:15529722chr19:16532287ENST00000595465-114484_5074586Zinc fingerC2H2 AKAP95-type 2
TgeneEPS15L1chr19:15529722chr19:16532287ENST00000248070-823172_184264865Calcium bindingOntology_term=ECO:0000255
TgeneEPS15L1chr19:15529722chr19:16532287ENST00000455140-824172_184264911Calcium bindingOntology_term=ECO:0000255
TgeneEPS15L1chr19:15529722chr19:16532287ENST00000535753-822172_184264755Calcium bindingOntology_term=ECO:0000255
TgeneEPS15L1chr19:15529722chr19:16532287ENST00000597937-816172_184264602Calcium bindingOntology_term=ECO:0000255
TgeneEPS15L1chr19:15529722chr19:16532287ENST00000248070-823127_215264865DomainEH 2
TgeneEPS15L1chr19:15529722chr19:16532287ENST00000248070-823159_194264865DomainEF-hand
TgeneEPS15L1chr19:15529722chr19:16532287ENST00000248070-82315_104264865DomainEH 1
TgeneEPS15L1chr19:15529722chr19:16532287ENST00000455140-824127_215264911DomainEH 2
TgeneEPS15L1chr19:15529722chr19:16532287ENST00000455140-824159_194264911DomainEF-hand
TgeneEPS15L1chr19:15529722chr19:16532287ENST00000455140-82415_104264911DomainEH 1
TgeneEPS15L1chr19:15529722chr19:16532287ENST00000535753-822127_215264755DomainEH 2
TgeneEPS15L1chr19:15529722chr19:16532287ENST00000535753-822159_194264755DomainEF-hand
TgeneEPS15L1chr19:15529722chr19:16532287ENST00000535753-82215_104264755DomainEH 1
TgeneEPS15L1chr19:15529722chr19:16532287ENST00000597937-816127_215264602DomainEH 2
TgeneEPS15L1chr19:15529722chr19:16532287ENST00000597937-816159_194264602DomainEF-hand
TgeneEPS15L1chr19:15529722chr19:16532287ENST00000597937-81615_104264602DomainEH 1


Top

FusionGeneSequence for AKAP8L_EPS15L1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.
>In-frame_AKAP8L_ENST00000397410_chr19_15529722_-_EPS15L1_ENST00000455140_chr19_16532287_-_651aa
MSYTANSELGGARGRQDAIXXDIPEDRPGPGWLREWPGGEGDLHALGPHPEPSSTHMGPGRYEANGEVKQRPIRVSYVFHSAEGQXRHRP
SSSPLAGHGPAFGERHARPGQFRLSRLRGVYWREGAXXHQSRDCPVTKREIFTGTRHSRKGRGNQTENQRGAGITKXPRPGNKQFAGARG
SETGCSRPPGRDGPAEGQAPRHAERRPAEVPGXDSDDLITENANPISGIXLKVPGRRSEPSQVGAEPIAAGGNPAGAEHSGWASPAGNHH
QVPEVNARRNQPGKEQTFPAAXKPPGGPQEPGAVXPGARWSPWCQPDRPGQPERRRLPGREGQFWSHGXSFQKXSLVIXQQHARVASGSF
PDRRPLQIXPIXRSXPLQRRPVPEXPLCRTADNFNRSIWRGPFQRKXPIPWLCHXRLLQETDKEXPIYLGSIHEKPFLTFEARPLXIQXS
LFILQCLLKRIRSLWNLRSLRKWVLQXCXRLCRLQPDVQAPTFWPFHLLLGRGRILRXPLXKXTGHSCSASEETCSSTAXTAQRXKYTCK
PAWFRRLSRGPRSIPATRGXQRRPVPKXKGVWGPVXWKRPICPLLCSXTFXGLCLGLCRLHLFWQXGAAAGVGQAGEREGGTGEAGAAAA

>In-frame_AKAP8L_ENST00000397410_chr19_15529722_-_EPS15L1_ENST00000248070_chr19_16532287_-_605aa
MSYTANSELGGARGRQDAIXXDIPEDRPGPGWLREWPGGEGDLHALGPHPEPSSTHMGPGRYEANGEVKQRPIRVSYVFHSAEGQXRHRP
SSSPLAGHGPAFGERHARPGQFRLSRLRGVYWREGAXXHQSRDCPVTKREIFTGTRHSRKGRGNQTENQRGAGITKXPRPGNKQFAGARG
SETGCSRPPGRDGPAEGQAPRHAERRPAEVPGXDSDDLITENANPISGIXLKVPGRRSEPSQVGAEPIAAGGNPAGAEHSGWASPAGNHH
QVPEVNARRNQPGKEQTFPAAXKPPGGPQEPGAVXPGARWSPWCQPDRPGQPERRRLPGREGQFWSHGXSFQKXSLVIXQQHARVASGSF
PDRRPLQIXPIXRSXPLQRRPVPEXPLCRTADNFNRSIWRGPFQRKXPIPWLCHXRLLQETDKEXPIYLGSIHEKPFLTFEARPLXIQXS
LFILQCLLKRIRSLWNLRSLRKWVLQXCXRLCRLQPDVQAPTFWPFHLLLGRGRILRXPLXKXTGHSCSASEETCSSTAXTAQRXKYTCK

>In-frame_AKAP8L_ENST00000397410_chr19_15529722_-_EPS15L1_ENST00000535753_chr19_16532287_-_495aa
MSYTANSELGGARGRQDAIXXDIPEDRPGPGWLREWPGGEGDLHALGPHPEPSSTHMGPGRYEANGEVKQRPIRVSYVFHSAEGQXRHRP
SSSPLAGHGPAFGERHARPGQFRLSRLRGVYWREGAXXHQSRDCPVTKREIFTGTRHSRKGRGNQTENQRGAGITKXPRPGNKQFAGARG
SETGCSRPPGRDGPAEGQAPRHAERRPAEVPGXDSDDLITENANPISGIXLKVPGRRSEPSQVGAEPIAAGGNPAGAEHSGWASPAGNHH
QVPEVNARRNQPGKEQTFPAAXKPPGGPQEPGAVXPGARWSPWCQPDRPGQPERRRLPGREGQFWSHGXSFQKXSLVIXQQHARVASGSF
PDRRPLQIXPIXRSXPLQRRPVPEXPLCRTADNFNRSIWRGPFQRKXPIPWLCHXRLLQETDKEXPIYLGSIHEKPFLTFEARPLXIQXS

>In-frame_AKAP8L_ENST00000397410_chr19_15529722_-_EPS15L1_ENST00000594975_chr19_16532287_-_497aa
MSYTANSELGGARGRQDAIXXDIPEDRPGPGWLREWPGGEGDLHALGPHPEPSSTHMGPGRYEANGEVKQRPIRVSYVFHSAEGQXRHRP
SSSPLAGHGPAFGERHARPGQFRLSRLRGVYWREGAXXHQSRDCPVTKREIFTGTRHSRKGRGNQTENQRGAGITKXPRPGNKQFAGARG
SETGCSRPPGRDGPAEGQAPRHAERRPAEVPGXDSDDLITENANPISGIXLKVPGRRSEPSQVGAEPIAAGGNPAGAEHSGWASPAGNHH
QVPEVNARRNQPGKEQTFPAAXKPPGGPQEPGAVXPGARWSPWCQPDRPGQPERRRLPGREGQFWSHGKGXSFQKXSLVIXQQHARVASG
SFPDRRPLQIXPIXRSXPLQRRPVPEXPLCRTADNFNRSIWRGPFQRKXPIPWLCHXRLLQETDKEXPIYLGSIHEKPFLTFEARPLXIQ

>In-frame_AKAP8L_ENST00000397410_chr19_15529722_-_EPS15L1_ENST00000602009_chr19_16532287_-_342aa
MSYTANSELGGARGRQDAIXXDIPEDRPGPGWLREWPGGEGDLHALGPHPEPSSTHMGPGRYEANGEVKQRPIRVSYVFHSAEGQXRHRP
SSSPLAGHGPAFGERHARPGQFRLSRLRGVYWREGAXXHQSRDCPVTKREIFTGTRHSRKGRGNQTENQRGAGITKXPRPGNKQFAGARG
SETGCSRPPGRDGPAEGQAPRHAERRPAEVPGXDSDDLITENANPISGIXLKVPGRRSEPSQVGAEPIAAGGNPAGAEHSGWASPAGNHH

>In-frame_AKAP8L_ENST00000397410_chr19_15529722_-_EPS15L1_ENST00000597937_chr19_16532287_-_342aa
MSYTANSELGGARGRQDAIXXDIPEDRPGPGWLREWPGGEGDLHALGPHPEPSSTHMGPGRYEANGEVKQRPIRVSYVFHSAEGQXRHRP
SSSPLAGHGPAFGERHARPGQFRLSRLRGVYWREGAXXHQSRDCPVTKREIFTGTRHSRKGRGNQTENQRGAGITKXPRPGNKQFAGARG
SETGCSRPPGRDGPAEGQAPRHAERRPAEVPGXDSDDLITENANPISGIXLKVPGRRSEPSQVGAEPIAAGGNPAGAEHSGWASPAGNHH

>In-frame_AKAP8L_ENST00000595465_chr19_15529722_-_EPS15L1_ENST00000455140_chr19_16532287_-_651aa
MSYTANSELGGARGRQDAIXXDIPEDRPGPGWLREWPGGEGDLHALGPHPEPSSTHMGPGRYEANGEVKQRPIRVSYVFHSAEGQXRHRP
SSSPLAGHGPAFGERHARPGQFRLSRLRGVYWREGAXXHQSRDCPVTKREIFTGTRHSRKGRGNQTENQRGAGITKXPRPGNKQFAGARG
SETGCSRPPGRDGPAEGQAPRHAERRPAEVPGXDSDDLITENANPISGIXLKVPGRRSEPSQVGAEPIAAGGNPAGAEHSGWASPAGNHH
QVPEVNARRNQPGKEQTFPAAXKPPGGPQEPGAVXPGARWSPWCQPDRPGQPERRRLPGREGQFWSHGXSFQKXSLVIXQQHARVASGSF
PDRRPLQIXPIXRSXPLQRRPVPEXPLCRTADNFNRSIWRGPFQRKXPIPWLCHXRLLQETDKEXPIYLGSIHEKPFLTFEARPLXIQXS
LFILQCLLKRIRSLWNLRSLRKWVLQXCXRLCRLQPDVQAPTFWPFHLLLGRGRILRXPLXKXTGHSCSASEETCSSTAXTAQRXKYTCK
PAWFRRLSRGPRSIPATRGXQRRPVPKXKGVWGPVXWKRPICPLLCSXTFXGLCLGLCRLHLFWQXGAAAGVGQAGEREGGTGEAGAAAA

>In-frame_AKAP8L_ENST00000595465_chr19_15529722_-_EPS15L1_ENST00000248070_chr19_16532287_-_605aa
MSYTANSELGGARGRQDAIXXDIPEDRPGPGWLREWPGGEGDLHALGPHPEPSSTHMGPGRYEANGEVKQRPIRVSYVFHSAEGQXRHRP
SSSPLAGHGPAFGERHARPGQFRLSRLRGVYWREGAXXHQSRDCPVTKREIFTGTRHSRKGRGNQTENQRGAGITKXPRPGNKQFAGARG
SETGCSRPPGRDGPAEGQAPRHAERRPAEVPGXDSDDLITENANPISGIXLKVPGRRSEPSQVGAEPIAAGGNPAGAEHSGWASPAGNHH
QVPEVNARRNQPGKEQTFPAAXKPPGGPQEPGAVXPGARWSPWCQPDRPGQPERRRLPGREGQFWSHGXSFQKXSLVIXQQHARVASGSF
PDRRPLQIXPIXRSXPLQRRPVPEXPLCRTADNFNRSIWRGPFQRKXPIPWLCHXRLLQETDKEXPIYLGSIHEKPFLTFEARPLXIQXS
LFILQCLLKRIRSLWNLRSLRKWVLQXCXRLCRLQPDVQAPTFWPFHLLLGRGRILRXPLXKXTGHSCSASEETCSSTAXTAQRXKYTCK

>In-frame_AKAP8L_ENST00000595465_chr19_15529722_-_EPS15L1_ENST00000535753_chr19_16532287_-_495aa
MSYTANSELGGARGRQDAIXXDIPEDRPGPGWLREWPGGEGDLHALGPHPEPSSTHMGPGRYEANGEVKQRPIRVSYVFHSAEGQXRHRP
SSSPLAGHGPAFGERHARPGQFRLSRLRGVYWREGAXXHQSRDCPVTKREIFTGTRHSRKGRGNQTENQRGAGITKXPRPGNKQFAGARG
SETGCSRPPGRDGPAEGQAPRHAERRPAEVPGXDSDDLITENANPISGIXLKVPGRRSEPSQVGAEPIAAGGNPAGAEHSGWASPAGNHH
QVPEVNARRNQPGKEQTFPAAXKPPGGPQEPGAVXPGARWSPWCQPDRPGQPERRRLPGREGQFWSHGXSFQKXSLVIXQQHARVASGSF
PDRRPLQIXPIXRSXPLQRRPVPEXPLCRTADNFNRSIWRGPFQRKXPIPWLCHXRLLQETDKEXPIYLGSIHEKPFLTFEARPLXIQXS

>In-frame_AKAP8L_ENST00000595465_chr19_15529722_-_EPS15L1_ENST00000594975_chr19_16532287_-_497aa
MSYTANSELGGARGRQDAIXXDIPEDRPGPGWLREWPGGEGDLHALGPHPEPSSTHMGPGRYEANGEVKQRPIRVSYVFHSAEGQXRHRP
SSSPLAGHGPAFGERHARPGQFRLSRLRGVYWREGAXXHQSRDCPVTKREIFTGTRHSRKGRGNQTENQRGAGITKXPRPGNKQFAGARG
SETGCSRPPGRDGPAEGQAPRHAERRPAEVPGXDSDDLITENANPISGIXLKVPGRRSEPSQVGAEPIAAGGNPAGAEHSGWASPAGNHH
QVPEVNARRNQPGKEQTFPAAXKPPGGPQEPGAVXPGARWSPWCQPDRPGQPERRRLPGREGQFWSHGKGXSFQKXSLVIXQQHARVASG
SFPDRRPLQIXPIXRSXPLQRRPVPEXPLCRTADNFNRSIWRGPFQRKXPIPWLCHXRLLQETDKEXPIYLGSIHEKPFLTFEARPLXIQ

>In-frame_AKAP8L_ENST00000595465_chr19_15529722_-_EPS15L1_ENST00000602009_chr19_16532287_-_342aa
MSYTANSELGGARGRQDAIXXDIPEDRPGPGWLREWPGGEGDLHALGPHPEPSSTHMGPGRYEANGEVKQRPIRVSYVFHSAEGQXRHRP
SSSPLAGHGPAFGERHARPGQFRLSRLRGVYWREGAXXHQSRDCPVTKREIFTGTRHSRKGRGNQTENQRGAGITKXPRPGNKQFAGARG
SETGCSRPPGRDGPAEGQAPRHAERRPAEVPGXDSDDLITENANPISGIXLKVPGRRSEPSQVGAEPIAAGGNPAGAEHSGWASPAGNHH

>In-frame_AKAP8L_ENST00000595465_chr19_15529722_-_EPS15L1_ENST00000597937_chr19_16532287_-_342aa
MSYTANSELGGARGRQDAIXXDIPEDRPGPGWLREWPGGEGDLHALGPHPEPSSTHMGPGRYEANGEVKQRPIRVSYVFHSAEGQXRHRP
SSSPLAGHGPAFGERHARPGQFRLSRLRGVYWREGAXXHQSRDCPVTKREIFTGTRHSRKGRGNQTENQRGAGITKXPRPGNKQFAGARG
SETGCSRPPGRDGPAEGQAPRHAERRPAEVPGXDSDDLITENANPISGIXLKVPGRRSEPSQVGAEPIAAGGNPAGAEHSGWASPAGNHH


* Fusion transcript sequences (only coding sequence (CDS) region).
>In-frame_AKAP8L_ENST00000397410_chr19_15529722_-_EPS15L1_ENST00000455140_chr19_16532287_-_1954nt
ATGAGCTACACAGCCAACAGTGAACTGGGTGGTGCCCGTGGCAGACAAGATGCGATTTGATGAGATATTCCTGAAGACCGACCTGGACCT
GGATGGCTACGTGAGTGGCCAGGAGGTGAAGGAGATCTTCATGCACTCGGGCCTCACCCAGAACCTTCTAGCACACATATGGGCCCTGGC
CGATACGAGGCAAACGGGGAAGTTAAGCAAAGACCAATTCGCGTTAGCTATGTATTTCATTCAGCAGAAGGTCAGTAAAGGCATCGACCC
TCCTCAAGTCCTCTCGCCGGACATGGTCCCGCCTTCGGAGAGAGGCACGCCCGGCCCGGACAGTTCAGGCTCTCTCGGCTCCGGGGAGTT
TACTGGCGTGAAGGAGCTTGATGACATCAGTCAAGAGATTGCCCAGTTACAAAGAGAGAAATATTCACTGGAACAAGACATTCGAGAAAA
GGAAGAGGCAATCAGACAGAAAACCAGCGAGGTGCAGGAATTACAAAATGACCTAGACCGGGAAACAAGCAGTTTGCAGGAGCTCGAGGC
TCAGAAACAGGATGCTCAAGACCGCCTGGACGAGATGGACCAGCAGAAGGCCAAGCTCCGAGACATGCTGAGCGACGTCCGGCAGAAGTG
CCAGGATGAGACTCAGATGATCTCATCACTGAAAACGCAAATCCAATCTCAGGAATCTGACTTAAAGTCCCAGGAAGACGATCTGAACCG
AGCCAAGTCGGAGCTGAACCGATTGCAGCAGGAGGAAACCCAGCTGGAGCAGAGCATTCAGGCTGGGCGAGTCCAGCTGGAAACCATCAT
CAAGTCCCTGAAGTCAACGCAAGACGAAATCAACCAGGCAAGGAGCAAACTTTCCCAGCTGCATGAAAGCCGCCAGGAGGCCCACAGGAG
CCTGGAGCAGTATGACCAGGTGCTCGATGGAGCCCATGGTGCCAGCCTGACCGACCTGGCCAACCTGAGCGAAGGCGTCTCCCTGGCAGA
GAGGGGCAGTTTTGGAGCCATGGATGATCCTTTCAAAAATAAAGCCTTGTTATTTAGCAACAACACGCAAGAGTTGCATCCGGATCCTTT
CCAGACAGAAGACCCCTTCAAATCTGACCCATTTAAAGGAGCTGACCCCTTCAAAGGCGACCCGTTCCAGAATGACCCCTTTGCAGAACA
GCAGACAACTTCAACAGATCCATTTGGAGGGGACCCTTTCAAAGAAAGTGACCCATTCCGTGGCTCTGCCACTGACGACTTCTTCAAGAA
ACAGACAAAGAATGACCCATTTACCTCGGATCCATTCACGAAAAACCCTTCCTTACCTTCGAAGCTCGACCCCTTTGAATCCAGTGATCC
CTTTTCATCCTCCAGTGTCTCCTCAAAAGGATCAGATCCCTTTGGAACCTTAGATCCCTTCGGAAGTGGGTCCTTCAATAGTGCTGAAGG
CTTTGCCGACTTCAGCCAGATGTCCAAGCCCCCACCTTCTGGCCCTTTCACCTCCTCCTTGGGAGGGGCAGGATTCTCAGATGACCCCTT
TAAAAGTAAACAGGACACTCCTGCTCTGCCTCCGAAGAAACCTGCTCCTCCACGGCCTAAACCGCCCAGCGGTAAAAGTACACCTGTAAG
CCAGCTTGGTTCCGCAGACTTTCCCGAGGCCCCCGATCCATTCCAGCCACTCGGGGCTGACAGCGGCGACCCGTTCCAAAGTAAAAAGGG
GTTTGGGGACCCGTTTAGTGGAAAAGACCCATTTGTCCCCTCCTCTGCAGCTAAACCTTCTAAGGCCTCTGCCTCGGGCTTTGCAGACTT
CACCTCTTTTGGCAATGAGGAGCAGCAGCTGGCGTGGGCCAAGCGGGAGAGCGAGAAGGCGGAACAGGAGAGGCTGGCGCGGCTGCGGCG

>In-frame_AKAP8L_ENST00000397410_chr19_15529722_-_EPS15L1_ENST00000248070_chr19_16532287_-_1816nt
ATGAGCTACACAGCCAACAGTGAACTGGGTGGTGCCCGTGGCAGACAAGATGCGATTTGATGAGATATTCCTGAAGACCGACCTGGACCT
GGATGGCTACGTGAGTGGCCAGGAGGTGAAGGAGATCTTCATGCACTCGGGCCTCACCCAGAACCTTCTAGCACACATATGGGCCCTGGC
CGATACGAGGCAAACGGGGAAGTTAAGCAAAGACCAATTCGCGTTAGCTATGTATTTCATTCAGCAGAAGGTCAGTAAAGGCATCGACCC
TCCTCAAGTCCTCTCGCCGGACATGGTCCCGCCTTCGGAGAGAGGCACGCCCGGCCCGGACAGTTCAGGCTCTCTCGGCTCCGGGGAGTT
TACTGGCGTGAAGGAGCTTGATGACATCAGTCAAGAGATTGCCCAGTTACAAAGAGAGAAATATTCACTGGAACAAGACATTCGAGAAAA
GGAAGAGGCAATCAGACAGAAAACCAGCGAGGTGCAGGAATTACAAAATGACCTAGACCGGGAAACAAGCAGTTTGCAGGAGCTCGAGGC
TCAGAAACAGGATGCTCAAGACCGCCTGGACGAGATGGACCAGCAGAAGGCCAAGCTCCGAGACATGCTGAGCGACGTCCGGCAGAAGTG
CCAGGATGAGACTCAGATGATCTCATCACTGAAAACGCAAATCCAATCTCAGGAATCTGACTTAAAGTCCCAGGAAGACGATCTGAACCG
AGCCAAGTCGGAGCTGAACCGATTGCAGCAGGAGGAAACCCAGCTGGAGCAGAGCATTCAGGCTGGGCGAGTCCAGCTGGAAACCATCAT
CAAGTCCCTGAAGTCAACGCAAGACGAAATCAACCAGGCAAGGAGCAAACTTTCCCAGCTGCATGAAAGCCGCCAGGAGGCCCACAGGAG
CCTGGAGCAGTATGACCAGGTGCTCGATGGAGCCCATGGTGCCAGCCTGACCGACCTGGCCAACCTGAGCGAAGGCGTCTCCCTGGCAGA
GAGGGGCAGTTTTGGAGCCATGGATGATCCTTTCAAAAATAAAGCCTTGTTATTTAGCAACAACACGCAAGAGTTGCATCCGGATCCTTT
CCAGACAGAAGACCCCTTCAAATCTGACCCATTTAAAGGAGCTGACCCCTTCAAAGGCGACCCGTTCCAGAATGACCCCTTTGCAGAACA
GCAGACAACTTCAACAGATCCATTTGGAGGGGACCCTTTCAAAGAAAGTGACCCATTCCGTGGCTCTGCCACTGACGACTTCTTCAAGAA
ACAGACAAAGAATGACCCATTTACCTCGGATCCATTCACGAAAAACCCTTCCTTACCTTCGAAGCTCGACCCCTTTGAATCCAGTGATCC
CTTTTCATCCTCCAGTGTCTCCTCAAAAGGATCAGATCCCTTTGGAACCTTAGATCCCTTCGGAAGTGGGTCCTTCAATAGTGCTGAAGG
CTTTGCCGACTTCAGCCAGATGTCCAAGCCCCCACCTTCTGGCCCTTTCACCTCCTCCTTGGGAGGGGCAGGATTCTCAGATGACCCCTT
TAAAAGTAAACAGGACACTCCTGCTCTGCCTCCGAAGAAACCTGCTCCTCCACGGCCTAAACCGCCCAGCGGTAAAAGTACACCTGTAAG
CCAGCTTGGTTCCGCAGACTTTCCCGAGGCCCCCGATCCATTCCAGCCACTCGGGGCTGACAGCGGCGACCCGTTCCAAAGTAAAAAGGG
GTTTGGGGACCCGTTTAGTGGAAAAGACCCATTTGTCCCCTCCTCTGCAGCTAAACCTTCTAAGGCCTCTGCCTCGGGCTTTGCAGACTT

>In-frame_AKAP8L_ENST00000397410_chr19_15529722_-_EPS15L1_ENST00000535753_chr19_16532287_-_1486nt
ATGAGCTACACAGCCAACAGTGAACTGGGTGGTGCCCGTGGCAGACAAGATGCGATTTGATGAGATATTCCTGAAGACCGACCTGGACCT
GGATGGCTACGTGAGTGGCCAGGAGGTGAAGGAGATCTTCATGCACTCGGGCCTCACCCAGAACCTTCTAGCACACATATGGGCCCTGGC
CGATACGAGGCAAACGGGGAAGTTAAGCAAAGACCAATTCGCGTTAGCTATGTATTTCATTCAGCAGAAGGTCAGTAAAGGCATCGACCC
TCCTCAAGTCCTCTCGCCGGACATGGTCCCGCCTTCGGAGAGAGGCACGCCCGGCCCGGACAGTTCAGGCTCTCTCGGCTCCGGGGAGTT
TACTGGCGTGAAGGAGCTTGATGACATCAGTCAAGAGATTGCCCAGTTACAAAGAGAGAAATATTCACTGGAACAAGACATTCGAGAAAA
GGAAGAGGCAATCAGACAGAAAACCAGCGAGGTGCAGGAATTACAAAATGACCTAGACCGGGAAACAAGCAGTTTGCAGGAGCTCGAGGC
TCAGAAACAGGATGCTCAAGACCGCCTGGACGAGATGGACCAGCAGAAGGCCAAGCTCCGAGACATGCTGAGCGACGTCCGGCAGAAGTG
CCAGGATGAGACTCAGATGATCTCATCACTGAAAACGCAAATCCAATCTCAGGAATCTGACTTAAAGTCCCAGGAAGACGATCTGAACCG
AGCCAAGTCGGAGCTGAACCGATTGCAGCAGGAGGAAACCCAGCTGGAGCAGAGCATTCAGGCTGGGCGAGTCCAGCTGGAAACCATCAT
CAAGTCCCTGAAGTCAACGCAAGACGAAATCAACCAGGCAAGGAGCAAACTTTCCCAGCTGCATGAAAGCCGCCAGGAGGCCCACAGGAG
CCTGGAGCAGTATGACCAGGTGCTCGATGGAGCCCATGGTGCCAGCCTGACCGACCTGGCCAACCTGAGCGAAGGCGTCTCCCTGGCAGA
GAGGGGCAGTTTTGGAGCCATGGATGATCCTTTCAAAAATAAAGCCTTGTTATTTAGCAACAACACGCAAGAGTTGCATCCGGATCCTTT
CCAGACAGAAGACCCCTTCAAATCTGACCCATTTAAAGGAGCTGACCCCTTCAAAGGCGACCCGTTCCAGAATGACCCCTTTGCAGAACA
GCAGACAACTTCAACAGATCCATTTGGAGGGGACCCTTTCAAAGAAAGTGACCCATTCCGTGGCTCTGCCACTGACGACTTCTTCAAGAA
ACAGACAAAGAATGACCCATTTACCTCGGATCCATTCACGAAAAACCCTTCCTTACCTTCGAAGCTCGACCCCTTTGAATCCAGTGATCC
CTTTTCATCCTCCAGTGTCTCCTCAAAAGGATCAGATCCCTTTGGAACCTTAGATCCCTTCGGAAGTGGGTCCTTCAATAGTGCTGAAGG

>In-frame_AKAP8L_ENST00000397410_chr19_15529722_-_EPS15L1_ENST00000594975_chr19_16532287_-_1492nt
ATGAGCTACACAGCCAACAGTGAACTGGGTGGTGCCCGTGGCAGACAAGATGCGATTTGATGAGATATTCCTGAAGACCGACCTGGACCT
GGATGGCTACGTGAGTGGCCAGGAGGTGAAGGAGATCTTCATGCACTCGGGCCTCACCCAGAACCTTCTAGCACACATATGGGCCCTGGC
CGATACGAGGCAAACGGGGAAGTTAAGCAAAGACCAATTCGCGTTAGCTATGTATTTCATTCAGCAGAAGGTCAGTAAAGGCATCGACCC
TCCTCAAGTCCTCTCGCCGGACATGGTCCCGCCTTCGGAGAGAGGCACGCCCGGCCCGGACAGTTCAGGCTCTCTCGGCTCCGGGGAGTT
TACTGGCGTGAAGGAGCTTGATGACATCAGTCAAGAGATTGCCCAGTTACAAAGAGAGAAATATTCACTGGAACAAGACATTCGAGAAAA
GGAAGAGGCAATCAGACAGAAAACCAGCGAGGTGCAGGAATTACAAAATGACCTAGACCGGGAAACAAGCAGTTTGCAGGAGCTCGAGGC
TCAGAAACAGGATGCTCAAGACCGCCTGGACGAGATGGACCAGCAGAAGGCCAAGCTCCGAGACATGCTGAGCGACGTCCGGCAGAAGTG
CCAGGATGAGACTCAGATGATCTCATCACTGAAAACGCAAATCCAATCTCAGGAATCTGACTTAAAGTCCCAGGAAGACGATCTGAACCG
AGCCAAGTCGGAGCTGAACCGATTGCAGCAGGAGGAAACCCAGCTGGAGCAGAGCATTCAGGCTGGGCGAGTCCAGCTGGAAACCATCAT
CAAGTCCCTGAAGTCAACGCAAGACGAAATCAACCAGGCAAGGAGCAAACTTTCCCAGCTGCATGAAAGCCGCCAGGAGGCCCACAGGAG
CCTGGAGCAGTATGACCAGGTGCTCGATGGAGCCCATGGTGCCAGCCTGACCGACCTGGCCAACCTGAGCGAAGGCGTCTCCCTGGCAGA
GAGGGGCAGTTTTGGAGCCATGGTAAAGGATGATCCTTTCAAAAATAAAGCCTTGTTATTTAGCAACAACACGCAAGAGTTGCATCCGGA
TCCTTTCCAGACAGAAGACCCCTTCAAATCTGACCCATTTAAAGGAGCTGACCCCTTCAAAGGCGACCCGTTCCAGAATGACCCCTTTGC
AGAACAGCAGACAACTTCAACAGATCCATTTGGAGGGGACCCTTTCAAAGAAAGTGACCCATTCCGTGGCTCTGCCACTGACGACTTCTT
CAAGAAACAGACAAAGAATGACCCATTTACCTCGGATCCATTCACGAAAAACCCTTCCTTACCTTCGAAGCTCGACCCCTTTGAATCCAG
TGATCCCTTTTCATCCTCCAGTGTCTCCTCAAAAGGATCAGATCCCTTTGGAACCTTAGATCCCTTCGGAAGTGGGTCCTTCAATAGTGC

>In-frame_AKAP8L_ENST00000397410_chr19_15529722_-_EPS15L1_ENST00000602009_chr19_16532287_-_1027nt
ATGAGCTACACAGCCAACAGTGAACTGGGTGGTGCCCGTGGCAGACAAGATGCGATTTGATGAGATATTCCTGAAGACCGACCTGGACCT
GGATGGCTACGTGAGTGGCCAGGAGGTGAAGGAGATCTTCATGCACTCGGGCCTCACCCAGAACCTTCTAGCACACATATGGGCCCTGGC
CGATACGAGGCAAACGGGGAAGTTAAGCAAAGACCAATTCGCGTTAGCTATGTATTTCATTCAGCAGAAGGTCAGTAAAGGCATCGACCC
TCCTCAAGTCCTCTCGCCGGACATGGTCCCGCCTTCGGAGAGAGGCACGCCCGGCCCGGACAGTTCAGGCTCTCTCGGCTCCGGGGAGTT
TACTGGCGTGAAGGAGCTTGATGACATCAGTCAAGAGATTGCCCAGTTACAAAGAGAGAAATATTCACTGGAACAAGACATTCGAGAAAA
GGAAGAGGCAATCAGACAGAAAACCAGCGAGGTGCAGGAATTACAAAATGACCTAGACCGGGAAACAAGCAGTTTGCAGGAGCTCGAGGC
TCAGAAACAGGATGCTCAAGACCGCCTGGACGAGATGGACCAGCAGAAGGCCAAGCTCCGAGACATGCTGAGCGACGTCCGGCAGAAGTG
CCAGGATGAGACTCAGATGATCTCATCACTGAAAACGCAAATCCAATCTCAGGAATCTGACTTAAAGTCCCAGGAAGACGATCTGAACCG
AGCCAAGTCGGAGCTGAACCGATTGCAGCAGGAGGAAACCCAGCTGGAGCAGAGCATTCAGGCTGGGCGAGTCCAGCTGGAAACCATCAT
CAAGTCCCTGAAGTCAACGCAAGACGAAATCAACCAGGCAAGGAGCAAACTTTCCCAGCTGCATGAAAGCCGCCAGGAGGCCCACAGGAG
CCTGGAGCAGTATGACCAGGTGCTCGATGGAGCCCATGGTGCCAGCCTGACCGACCTGGCCAACCTGAGCGAAGGCGTCTCCCTGGCAGA

>In-frame_AKAP8L_ENST00000397410_chr19_15529722_-_EPS15L1_ENST00000597937_chr19_16532287_-_1027nt
ATGAGCTACACAGCCAACAGTGAACTGGGTGGTGCCCGTGGCAGACAAGATGCGATTTGATGAGATATTCCTGAAGACCGACCTGGACCT
GGATGGCTACGTGAGTGGCCAGGAGGTGAAGGAGATCTTCATGCACTCGGGCCTCACCCAGAACCTTCTAGCACACATATGGGCCCTGGC
CGATACGAGGCAAACGGGGAAGTTAAGCAAAGACCAATTCGCGTTAGCTATGTATTTCATTCAGCAGAAGGTCAGTAAAGGCATCGACCC
TCCTCAAGTCCTCTCGCCGGACATGGTCCCGCCTTCGGAGAGAGGCACGCCCGGCCCGGACAGTTCAGGCTCTCTCGGCTCCGGGGAGTT
TACTGGCGTGAAGGAGCTTGATGACATCAGTCAAGAGATTGCCCAGTTACAAAGAGAGAAATATTCACTGGAACAAGACATTCGAGAAAA
GGAAGAGGCAATCAGACAGAAAACCAGCGAGGTGCAGGAATTACAAAATGACCTAGACCGGGAAACAAGCAGTTTGCAGGAGCTCGAGGC
TCAGAAACAGGATGCTCAAGACCGCCTGGACGAGATGGACCAGCAGAAGGCCAAGCTCCGAGACATGCTGAGCGACGTCCGGCAGAAGTG
CCAGGATGAGACTCAGATGATCTCATCACTGAAAACGCAAATCCAATCTCAGGAATCTGACTTAAAGTCCCAGGAAGACGATCTGAACCG
AGCCAAGTCGGAGCTGAACCGATTGCAGCAGGAGGAAACCCAGCTGGAGCAGAGCATTCAGGCTGGGCGAGTCCAGCTGGAAACCATCAT
CAAGTCCCTGAAGTCAACGCAAGACGAAATCAACCAGGCAAGGAGCAAACTTTCCCAGCTGCATGAAAGCCGCCAGGAGGCCCACAGGAG
CCTGGAGCAGTATGACCAGGTGCTCGATGGAGCCCATGGTGCCAGCCTGACCGACCTGGCCAACCTGAGCGAAGGCGTCTCCCTGGCAGA

>In-frame_AKAP8L_ENST00000595465_chr19_15529722_-_EPS15L1_ENST00000455140_chr19_16532287_-_1954nt
ATGAGCTACACAGCCAACAGTGAACTGGGTGGTGCCCGTGGCAGACAAGATGCGATTTGATGAGATATTCCTGAAGACCGACCTGGACCT
GGATGGCTACGTGAGTGGCCAGGAGGTGAAGGAGATCTTCATGCACTCGGGCCTCACCCAGAACCTTCTAGCACACATATGGGCCCTGGC
CGATACGAGGCAAACGGGGAAGTTAAGCAAAGACCAATTCGCGTTAGCTATGTATTTCATTCAGCAGAAGGTCAGTAAAGGCATCGACCC
TCCTCAAGTCCTCTCGCCGGACATGGTCCCGCCTTCGGAGAGAGGCACGCCCGGCCCGGACAGTTCAGGCTCTCTCGGCTCCGGGGAGTT
TACTGGCGTGAAGGAGCTTGATGACATCAGTCAAGAGATTGCCCAGTTACAAAGAGAGAAATATTCACTGGAACAAGACATTCGAGAAAA
GGAAGAGGCAATCAGACAGAAAACCAGCGAGGTGCAGGAATTACAAAATGACCTAGACCGGGAAACAAGCAGTTTGCAGGAGCTCGAGGC
TCAGAAACAGGATGCTCAAGACCGCCTGGACGAGATGGACCAGCAGAAGGCCAAGCTCCGAGACATGCTGAGCGACGTCCGGCAGAAGTG
CCAGGATGAGACTCAGATGATCTCATCACTGAAAACGCAAATCCAATCTCAGGAATCTGACTTAAAGTCCCAGGAAGACGATCTGAACCG
AGCCAAGTCGGAGCTGAACCGATTGCAGCAGGAGGAAACCCAGCTGGAGCAGAGCATTCAGGCTGGGCGAGTCCAGCTGGAAACCATCAT
CAAGTCCCTGAAGTCAACGCAAGACGAAATCAACCAGGCAAGGAGCAAACTTTCCCAGCTGCATGAAAGCCGCCAGGAGGCCCACAGGAG
CCTGGAGCAGTATGACCAGGTGCTCGATGGAGCCCATGGTGCCAGCCTGACCGACCTGGCCAACCTGAGCGAAGGCGTCTCCCTGGCAGA
GAGGGGCAGTTTTGGAGCCATGGATGATCCTTTCAAAAATAAAGCCTTGTTATTTAGCAACAACACGCAAGAGTTGCATCCGGATCCTTT
CCAGACAGAAGACCCCTTCAAATCTGACCCATTTAAAGGAGCTGACCCCTTCAAAGGCGACCCGTTCCAGAATGACCCCTTTGCAGAACA
GCAGACAACTTCAACAGATCCATTTGGAGGGGACCCTTTCAAAGAAAGTGACCCATTCCGTGGCTCTGCCACTGACGACTTCTTCAAGAA
ACAGACAAAGAATGACCCATTTACCTCGGATCCATTCACGAAAAACCCTTCCTTACCTTCGAAGCTCGACCCCTTTGAATCCAGTGATCC
CTTTTCATCCTCCAGTGTCTCCTCAAAAGGATCAGATCCCTTTGGAACCTTAGATCCCTTCGGAAGTGGGTCCTTCAATAGTGCTGAAGG
CTTTGCCGACTTCAGCCAGATGTCCAAGCCCCCACCTTCTGGCCCTTTCACCTCCTCCTTGGGAGGGGCAGGATTCTCAGATGACCCCTT
TAAAAGTAAACAGGACACTCCTGCTCTGCCTCCGAAGAAACCTGCTCCTCCACGGCCTAAACCGCCCAGCGGTAAAAGTACACCTGTAAG
CCAGCTTGGTTCCGCAGACTTTCCCGAGGCCCCCGATCCATTCCAGCCACTCGGGGCTGACAGCGGCGACCCGTTCCAAAGTAAAAAGGG
GTTTGGGGACCCGTTTAGTGGAAAAGACCCATTTGTCCCCTCCTCTGCAGCTAAACCTTCTAAGGCCTCTGCCTCGGGCTTTGCAGACTT
CACCTCTTTTGGCAATGAGGAGCAGCAGCTGGCGTGGGCCAAGCGGGAGAGCGAGAAGGCGGAACAGGAGAGGCTGGCGCGGCTGCGGCG

>In-frame_AKAP8L_ENST00000595465_chr19_15529722_-_EPS15L1_ENST00000248070_chr19_16532287_-_1816nt
ATGAGCTACACAGCCAACAGTGAACTGGGTGGTGCCCGTGGCAGACAAGATGCGATTTGATGAGATATTCCTGAAGACCGACCTGGACCT
GGATGGCTACGTGAGTGGCCAGGAGGTGAAGGAGATCTTCATGCACTCGGGCCTCACCCAGAACCTTCTAGCACACATATGGGCCCTGGC
CGATACGAGGCAAACGGGGAAGTTAAGCAAAGACCAATTCGCGTTAGCTATGTATTTCATTCAGCAGAAGGTCAGTAAAGGCATCGACCC
TCCTCAAGTCCTCTCGCCGGACATGGTCCCGCCTTCGGAGAGAGGCACGCCCGGCCCGGACAGTTCAGGCTCTCTCGGCTCCGGGGAGTT
TACTGGCGTGAAGGAGCTTGATGACATCAGTCAAGAGATTGCCCAGTTACAAAGAGAGAAATATTCACTGGAACAAGACATTCGAGAAAA
GGAAGAGGCAATCAGACAGAAAACCAGCGAGGTGCAGGAATTACAAAATGACCTAGACCGGGAAACAAGCAGTTTGCAGGAGCTCGAGGC
TCAGAAACAGGATGCTCAAGACCGCCTGGACGAGATGGACCAGCAGAAGGCCAAGCTCCGAGACATGCTGAGCGACGTCCGGCAGAAGTG
CCAGGATGAGACTCAGATGATCTCATCACTGAAAACGCAAATCCAATCTCAGGAATCTGACTTAAAGTCCCAGGAAGACGATCTGAACCG
AGCCAAGTCGGAGCTGAACCGATTGCAGCAGGAGGAAACCCAGCTGGAGCAGAGCATTCAGGCTGGGCGAGTCCAGCTGGAAACCATCAT
CAAGTCCCTGAAGTCAACGCAAGACGAAATCAACCAGGCAAGGAGCAAACTTTCCCAGCTGCATGAAAGCCGCCAGGAGGCCCACAGGAG
CCTGGAGCAGTATGACCAGGTGCTCGATGGAGCCCATGGTGCCAGCCTGACCGACCTGGCCAACCTGAGCGAAGGCGTCTCCCTGGCAGA
GAGGGGCAGTTTTGGAGCCATGGATGATCCTTTCAAAAATAAAGCCTTGTTATTTAGCAACAACACGCAAGAGTTGCATCCGGATCCTTT
CCAGACAGAAGACCCCTTCAAATCTGACCCATTTAAAGGAGCTGACCCCTTCAAAGGCGACCCGTTCCAGAATGACCCCTTTGCAGAACA
GCAGACAACTTCAACAGATCCATTTGGAGGGGACCCTTTCAAAGAAAGTGACCCATTCCGTGGCTCTGCCACTGACGACTTCTTCAAGAA
ACAGACAAAGAATGACCCATTTACCTCGGATCCATTCACGAAAAACCCTTCCTTACCTTCGAAGCTCGACCCCTTTGAATCCAGTGATCC
CTTTTCATCCTCCAGTGTCTCCTCAAAAGGATCAGATCCCTTTGGAACCTTAGATCCCTTCGGAAGTGGGTCCTTCAATAGTGCTGAAGG
CTTTGCCGACTTCAGCCAGATGTCCAAGCCCCCACCTTCTGGCCCTTTCACCTCCTCCTTGGGAGGGGCAGGATTCTCAGATGACCCCTT
TAAAAGTAAACAGGACACTCCTGCTCTGCCTCCGAAGAAACCTGCTCCTCCACGGCCTAAACCGCCCAGCGGTAAAAGTACACCTGTAAG
CCAGCTTGGTTCCGCAGACTTTCCCGAGGCCCCCGATCCATTCCAGCCACTCGGGGCTGACAGCGGCGACCCGTTCCAAAGTAAAAAGGG
GTTTGGGGACCCGTTTAGTGGAAAAGACCCATTTGTCCCCTCCTCTGCAGCTAAACCTTCTAAGGCCTCTGCCTCGGGCTTTGCAGACTT

>In-frame_AKAP8L_ENST00000595465_chr19_15529722_-_EPS15L1_ENST00000535753_chr19_16532287_-_1486nt
ATGAGCTACACAGCCAACAGTGAACTGGGTGGTGCCCGTGGCAGACAAGATGCGATTTGATGAGATATTCCTGAAGACCGACCTGGACCT
GGATGGCTACGTGAGTGGCCAGGAGGTGAAGGAGATCTTCATGCACTCGGGCCTCACCCAGAACCTTCTAGCACACATATGGGCCCTGGC
CGATACGAGGCAAACGGGGAAGTTAAGCAAAGACCAATTCGCGTTAGCTATGTATTTCATTCAGCAGAAGGTCAGTAAAGGCATCGACCC
TCCTCAAGTCCTCTCGCCGGACATGGTCCCGCCTTCGGAGAGAGGCACGCCCGGCCCGGACAGTTCAGGCTCTCTCGGCTCCGGGGAGTT
TACTGGCGTGAAGGAGCTTGATGACATCAGTCAAGAGATTGCCCAGTTACAAAGAGAGAAATATTCACTGGAACAAGACATTCGAGAAAA
GGAAGAGGCAATCAGACAGAAAACCAGCGAGGTGCAGGAATTACAAAATGACCTAGACCGGGAAACAAGCAGTTTGCAGGAGCTCGAGGC
TCAGAAACAGGATGCTCAAGACCGCCTGGACGAGATGGACCAGCAGAAGGCCAAGCTCCGAGACATGCTGAGCGACGTCCGGCAGAAGTG
CCAGGATGAGACTCAGATGATCTCATCACTGAAAACGCAAATCCAATCTCAGGAATCTGACTTAAAGTCCCAGGAAGACGATCTGAACCG
AGCCAAGTCGGAGCTGAACCGATTGCAGCAGGAGGAAACCCAGCTGGAGCAGAGCATTCAGGCTGGGCGAGTCCAGCTGGAAACCATCAT
CAAGTCCCTGAAGTCAACGCAAGACGAAATCAACCAGGCAAGGAGCAAACTTTCCCAGCTGCATGAAAGCCGCCAGGAGGCCCACAGGAG
CCTGGAGCAGTATGACCAGGTGCTCGATGGAGCCCATGGTGCCAGCCTGACCGACCTGGCCAACCTGAGCGAAGGCGTCTCCCTGGCAGA
GAGGGGCAGTTTTGGAGCCATGGATGATCCTTTCAAAAATAAAGCCTTGTTATTTAGCAACAACACGCAAGAGTTGCATCCGGATCCTTT
CCAGACAGAAGACCCCTTCAAATCTGACCCATTTAAAGGAGCTGACCCCTTCAAAGGCGACCCGTTCCAGAATGACCCCTTTGCAGAACA
GCAGACAACTTCAACAGATCCATTTGGAGGGGACCCTTTCAAAGAAAGTGACCCATTCCGTGGCTCTGCCACTGACGACTTCTTCAAGAA
ACAGACAAAGAATGACCCATTTACCTCGGATCCATTCACGAAAAACCCTTCCTTACCTTCGAAGCTCGACCCCTTTGAATCCAGTGATCC
CTTTTCATCCTCCAGTGTCTCCTCAAAAGGATCAGATCCCTTTGGAACCTTAGATCCCTTCGGAAGTGGGTCCTTCAATAGTGCTGAAGG

>In-frame_AKAP8L_ENST00000595465_chr19_15529722_-_EPS15L1_ENST00000594975_chr19_16532287_-_1492nt
ATGAGCTACACAGCCAACAGTGAACTGGGTGGTGCCCGTGGCAGACAAGATGCGATTTGATGAGATATTCCTGAAGACCGACCTGGACCT
GGATGGCTACGTGAGTGGCCAGGAGGTGAAGGAGATCTTCATGCACTCGGGCCTCACCCAGAACCTTCTAGCACACATATGGGCCCTGGC
CGATACGAGGCAAACGGGGAAGTTAAGCAAAGACCAATTCGCGTTAGCTATGTATTTCATTCAGCAGAAGGTCAGTAAAGGCATCGACCC
TCCTCAAGTCCTCTCGCCGGACATGGTCCCGCCTTCGGAGAGAGGCACGCCCGGCCCGGACAGTTCAGGCTCTCTCGGCTCCGGGGAGTT
TACTGGCGTGAAGGAGCTTGATGACATCAGTCAAGAGATTGCCCAGTTACAAAGAGAGAAATATTCACTGGAACAAGACATTCGAGAAAA
GGAAGAGGCAATCAGACAGAAAACCAGCGAGGTGCAGGAATTACAAAATGACCTAGACCGGGAAACAAGCAGTTTGCAGGAGCTCGAGGC
TCAGAAACAGGATGCTCAAGACCGCCTGGACGAGATGGACCAGCAGAAGGCCAAGCTCCGAGACATGCTGAGCGACGTCCGGCAGAAGTG
CCAGGATGAGACTCAGATGATCTCATCACTGAAAACGCAAATCCAATCTCAGGAATCTGACTTAAAGTCCCAGGAAGACGATCTGAACCG
AGCCAAGTCGGAGCTGAACCGATTGCAGCAGGAGGAAACCCAGCTGGAGCAGAGCATTCAGGCTGGGCGAGTCCAGCTGGAAACCATCAT
CAAGTCCCTGAAGTCAACGCAAGACGAAATCAACCAGGCAAGGAGCAAACTTTCCCAGCTGCATGAAAGCCGCCAGGAGGCCCACAGGAG
CCTGGAGCAGTATGACCAGGTGCTCGATGGAGCCCATGGTGCCAGCCTGACCGACCTGGCCAACCTGAGCGAAGGCGTCTCCCTGGCAGA
GAGGGGCAGTTTTGGAGCCATGGTAAAGGATGATCCTTTCAAAAATAAAGCCTTGTTATTTAGCAACAACACGCAAGAGTTGCATCCGGA
TCCTTTCCAGACAGAAGACCCCTTCAAATCTGACCCATTTAAAGGAGCTGACCCCTTCAAAGGCGACCCGTTCCAGAATGACCCCTTTGC
AGAACAGCAGACAACTTCAACAGATCCATTTGGAGGGGACCCTTTCAAAGAAAGTGACCCATTCCGTGGCTCTGCCACTGACGACTTCTT
CAAGAAACAGACAAAGAATGACCCATTTACCTCGGATCCATTCACGAAAAACCCTTCCTTACCTTCGAAGCTCGACCCCTTTGAATCCAG
TGATCCCTTTTCATCCTCCAGTGTCTCCTCAAAAGGATCAGATCCCTTTGGAACCTTAGATCCCTTCGGAAGTGGGTCCTTCAATAGTGC

>In-frame_AKAP8L_ENST00000595465_chr19_15529722_-_EPS15L1_ENST00000602009_chr19_16532287_-_1027nt
ATGAGCTACACAGCCAACAGTGAACTGGGTGGTGCCCGTGGCAGACAAGATGCGATTTGATGAGATATTCCTGAAGACCGACCTGGACCT
GGATGGCTACGTGAGTGGCCAGGAGGTGAAGGAGATCTTCATGCACTCGGGCCTCACCCAGAACCTTCTAGCACACATATGGGCCCTGGC
CGATACGAGGCAAACGGGGAAGTTAAGCAAAGACCAATTCGCGTTAGCTATGTATTTCATTCAGCAGAAGGTCAGTAAAGGCATCGACCC
TCCTCAAGTCCTCTCGCCGGACATGGTCCCGCCTTCGGAGAGAGGCACGCCCGGCCCGGACAGTTCAGGCTCTCTCGGCTCCGGGGAGTT
TACTGGCGTGAAGGAGCTTGATGACATCAGTCAAGAGATTGCCCAGTTACAAAGAGAGAAATATTCACTGGAACAAGACATTCGAGAAAA
GGAAGAGGCAATCAGACAGAAAACCAGCGAGGTGCAGGAATTACAAAATGACCTAGACCGGGAAACAAGCAGTTTGCAGGAGCTCGAGGC
TCAGAAACAGGATGCTCAAGACCGCCTGGACGAGATGGACCAGCAGAAGGCCAAGCTCCGAGACATGCTGAGCGACGTCCGGCAGAAGTG
CCAGGATGAGACTCAGATGATCTCATCACTGAAAACGCAAATCCAATCTCAGGAATCTGACTTAAAGTCCCAGGAAGACGATCTGAACCG
AGCCAAGTCGGAGCTGAACCGATTGCAGCAGGAGGAAACCCAGCTGGAGCAGAGCATTCAGGCTGGGCGAGTCCAGCTGGAAACCATCAT
CAAGTCCCTGAAGTCAACGCAAGACGAAATCAACCAGGCAAGGAGCAAACTTTCCCAGCTGCATGAAAGCCGCCAGGAGGCCCACAGGAG
CCTGGAGCAGTATGACCAGGTGCTCGATGGAGCCCATGGTGCCAGCCTGACCGACCTGGCCAACCTGAGCGAAGGCGTCTCCCTGGCAGA

>In-frame_AKAP8L_ENST00000595465_chr19_15529722_-_EPS15L1_ENST00000597937_chr19_16532287_-_1027nt
ATGAGCTACACAGCCAACAGTGAACTGGGTGGTGCCCGTGGCAGACAAGATGCGATTTGATGAGATATTCCTGAAGACCGACCTGGACCT
GGATGGCTACGTGAGTGGCCAGGAGGTGAAGGAGATCTTCATGCACTCGGGCCTCACCCAGAACCTTCTAGCACACATATGGGCCCTGGC
CGATACGAGGCAAACGGGGAAGTTAAGCAAAGACCAATTCGCGTTAGCTATGTATTTCATTCAGCAGAAGGTCAGTAAAGGCATCGACCC
TCCTCAAGTCCTCTCGCCGGACATGGTCCCGCCTTCGGAGAGAGGCACGCCCGGCCCGGACAGTTCAGGCTCTCTCGGCTCCGGGGAGTT
TACTGGCGTGAAGGAGCTTGATGACATCAGTCAAGAGATTGCCCAGTTACAAAGAGAGAAATATTCACTGGAACAAGACATTCGAGAAAA
GGAAGAGGCAATCAGACAGAAAACCAGCGAGGTGCAGGAATTACAAAATGACCTAGACCGGGAAACAAGCAGTTTGCAGGAGCTCGAGGC
TCAGAAACAGGATGCTCAAGACCGCCTGGACGAGATGGACCAGCAGAAGGCCAAGCTCCGAGACATGCTGAGCGACGTCCGGCAGAAGTG
CCAGGATGAGACTCAGATGATCTCATCACTGAAAACGCAAATCCAATCTCAGGAATCTGACTTAAAGTCCCAGGAAGACGATCTGAACCG
AGCCAAGTCGGAGCTGAACCGATTGCAGCAGGAGGAAACCCAGCTGGAGCAGAGCATTCAGGCTGGGCGAGTCCAGCTGGAAACCATCAT
CAAGTCCCTGAAGTCAACGCAAGACGAAATCAACCAGGCAAGGAGCAAACTTTCCCAGCTGCATGAAAGCCGCCAGGAGGCCCACAGGAG
CCTGGAGCAGTATGACCAGGTGCTCGATGGAGCCCATGGTGCCAGCCTGACCGACCTGGCCAACCTGAGCGAAGGCGTCTCCCTGGCAGA


* Fusion transcript sequences (Full-length transcript).
>In-frame_AKAP8L_ENST00000397410_chr19_15529722_-_EPS15L1_ENST00000455140_chr19_16532287_-_2551nt
GAGCCAATGCGGTCGGGAGGCGGGGCTCGGGTGTGTGTGGAGGGGACCCTGTGGTTAGCAGCAGCTATCGCAGCGTCGGATGTTCAGAGC
AGCAGAAGCCGGCGTCGTCGGATGTTGTGTTGCCCGCCACCATGAGCTACACAGCCAACAGTGAACTGGGTGGTGCCCGTGGCAGACAAG
ATGCGATTTGATGAGATATTCCTGAAGACCGACCTGGACCTGGATGGCTACGTGAGTGGCCAGGAGGTGAAGGAGATCTTCATGCACTCG
GGCCTCACCCAGAACCTTCTAGCACACATATGGGCCCTGGCCGATACGAGGCAAACGGGGAAGTTAAGCAAAGACCAATTCGCGTTAGCT
ATGTATTTCATTCAGCAGAAGGTCAGTAAAGGCATCGACCCTCCTCAAGTCCTCTCGCCGGACATGGTCCCGCCTTCGGAGAGAGGCACG
CCCGGCCCGGACAGTTCAGGCTCTCTCGGCTCCGGGGAGTTTACTGGCGTGAAGGAGCTTGATGACATCAGTCAAGAGATTGCCCAGTTA
CAAAGAGAGAAATATTCACTGGAACAAGACATTCGAGAAAAGGAAGAGGCAATCAGACAGAAAACCAGCGAGGTGCAGGAATTACAAAAT
GACCTAGACCGGGAAACAAGCAGTTTGCAGGAGCTCGAGGCTCAGAAACAGGATGCTCAAGACCGCCTGGACGAGATGGACCAGCAGAAG
GCCAAGCTCCGAGACATGCTGAGCGACGTCCGGCAGAAGTGCCAGGATGAGACTCAGATGATCTCATCACTGAAAACGCAAATCCAATCT
CAGGAATCTGACTTAAAGTCCCAGGAAGACGATCTGAACCGAGCCAAGTCGGAGCTGAACCGATTGCAGCAGGAGGAAACCCAGCTGGAG
CAGAGCATTCAGGCTGGGCGAGTCCAGCTGGAAACCATCATCAAGTCCCTGAAGTCAACGCAAGACGAAATCAACCAGGCAAGGAGCAAA
CTTTCCCAGCTGCATGAAAGCCGCCAGGAGGCCCACAGGAGCCTGGAGCAGTATGACCAGGTGCTCGATGGAGCCCATGGTGCCAGCCTG
ACCGACCTGGCCAACCTGAGCGAAGGCGTCTCCCTGGCAGAGAGGGGCAGTTTTGGAGCCATGGATGATCCTTTCAAAAATAAAGCCTTG
TTATTTAGCAACAACACGCAAGAGTTGCATCCGGATCCTTTCCAGACAGAAGACCCCTTCAAATCTGACCCATTTAAAGGAGCTGACCCC
TTCAAAGGCGACCCGTTCCAGAATGACCCCTTTGCAGAACAGCAGACAACTTCAACAGATCCATTTGGAGGGGACCCTTTCAAAGAAAGT
GACCCATTCCGTGGCTCTGCCACTGACGACTTCTTCAAGAAACAGACAAAGAATGACCCATTTACCTCGGATCCATTCACGAAAAACCCT
TCCTTACCTTCGAAGCTCGACCCCTTTGAATCCAGTGATCCCTTTTCATCCTCCAGTGTCTCCTCAAAAGGATCAGATCCCTTTGGAACC
TTAGATCCCTTCGGAAGTGGGTCCTTCAATAGTGCTGAAGGCTTTGCCGACTTCAGCCAGATGTCCAAGCCCCCACCTTCTGGCCCTTTC
ACCTCCTCCTTGGGAGGGGCAGGATTCTCAGATGACCCCTTTAAAAGTAAACAGGACACTCCTGCTCTGCCTCCGAAGAAACCTGCTCCT
CCACGGCCTAAACCGCCCAGCGGTAAAAGTACACCTGTAAGCCAGCTTGGTTCCGCAGACTTTCCCGAGGCCCCCGATCCATTCCAGCCA
CTCGGGGCTGACAGCGGCGACCCGTTCCAAAGTAAAAAGGGGTTTGGGGACCCGTTTAGTGGAAAAGACCCATTTGTCCCCTCCTCTGCA
GCTAAACCTTCTAAGGCCTCTGCCTCGGGCTTTGCAGACTTCACCTCTTTTGGCAATGAGGAGCAGCAGCTGGCGTGGGCCAAGCGGGAG
AGCGAGAAGGCGGAACAGGAGAGGCTGGCGCGGCTGCGGCGGCAGGAGCAGGAGGACCTGGAACTGGCCATCGCGCTCAGCAAGGCTGAC
ATGCCTGCCGCCTAGGCGAGGGCCGTGTGTAGGCGGGACAGGGCACGGGCGGGTTCCAGAGAGGGGGCAGTGCAGATGTCTATATATACA
CACACACACCGTCGCCACCGTACTCCAAGGACCGGGACTCGGGGGCTTGTTCAGGGTGAGCAGACTCGGCTGCAAGACCTGGAAAGGTCA
CATCTCCTGGGGAAGCCCTTACAGAGGCCTTGGCCACCACTTCTGCAGGTCCGTCTCTCCACTGTGCCATCCCCCCCGGGGCTGACTGCC
TCCCGCTCTTCCTCTGGGGACGAACACACAGCGGTCAGTCGAGGAGAGGAAGCACCCAGGGCTTCCCCGCCTCCTCCCTACTCATAGCTG
CAGACATCCCCACCCGCCCTCCCACGCATCAGTCAGACACTCCCCCAGTGGTGTATGCACTCGTTGTATAAAATGAAGTTTGAATGATTA

>In-frame_AKAP8L_ENST00000397410_chr19_15529722_-_EPS15L1_ENST00000248070_chr19_16532287_-_2136nt
GAGCCAATGCGGTCGGGAGGCGGGGCTCGGGTGTGTGTGGAGGGGACCCTGTGGTTAGCAGCAGCTATCGCAGCGTCGGATGTTCAGAGC
AGCAGAAGCCGGCGTCGTCGGATGTTGTGTTGCCCGCCACCATGAGCTACACAGCCAACAGTGAACTGGGTGGTGCCCGTGGCAGACAAG
ATGCGATTTGATGAGATATTCCTGAAGACCGACCTGGACCTGGATGGCTACGTGAGTGGCCAGGAGGTGAAGGAGATCTTCATGCACTCG
GGCCTCACCCAGAACCTTCTAGCACACATATGGGCCCTGGCCGATACGAGGCAAACGGGGAAGTTAAGCAAAGACCAATTCGCGTTAGCT
ATGTATTTCATTCAGCAGAAGGTCAGTAAAGGCATCGACCCTCCTCAAGTCCTCTCGCCGGACATGGTCCCGCCTTCGGAGAGAGGCACG
CCCGGCCCGGACAGTTCAGGCTCTCTCGGCTCCGGGGAGTTTACTGGCGTGAAGGAGCTTGATGACATCAGTCAAGAGATTGCCCAGTTA
CAAAGAGAGAAATATTCACTGGAACAAGACATTCGAGAAAAGGAAGAGGCAATCAGACAGAAAACCAGCGAGGTGCAGGAATTACAAAAT
GACCTAGACCGGGAAACAAGCAGTTTGCAGGAGCTCGAGGCTCAGAAACAGGATGCTCAAGACCGCCTGGACGAGATGGACCAGCAGAAG
GCCAAGCTCCGAGACATGCTGAGCGACGTCCGGCAGAAGTGCCAGGATGAGACTCAGATGATCTCATCACTGAAAACGCAAATCCAATCT
CAGGAATCTGACTTAAAGTCCCAGGAAGACGATCTGAACCGAGCCAAGTCGGAGCTGAACCGATTGCAGCAGGAGGAAACCCAGCTGGAG
CAGAGCATTCAGGCTGGGCGAGTCCAGCTGGAAACCATCATCAAGTCCCTGAAGTCAACGCAAGACGAAATCAACCAGGCAAGGAGCAAA
CTTTCCCAGCTGCATGAAAGCCGCCAGGAGGCCCACAGGAGCCTGGAGCAGTATGACCAGGTGCTCGATGGAGCCCATGGTGCCAGCCTG
ACCGACCTGGCCAACCTGAGCGAAGGCGTCTCCCTGGCAGAGAGGGGCAGTTTTGGAGCCATGGATGATCCTTTCAAAAATAAAGCCTTG
TTATTTAGCAACAACACGCAAGAGTTGCATCCGGATCCTTTCCAGACAGAAGACCCCTTCAAATCTGACCCATTTAAAGGAGCTGACCCC
TTCAAAGGCGACCCGTTCCAGAATGACCCCTTTGCAGAACAGCAGACAACTTCAACAGATCCATTTGGAGGGGACCCTTTCAAAGAAAGT
GACCCATTCCGTGGCTCTGCCACTGACGACTTCTTCAAGAAACAGACAAAGAATGACCCATTTACCTCGGATCCATTCACGAAAAACCCT
TCCTTACCTTCGAAGCTCGACCCCTTTGAATCCAGTGATCCCTTTTCATCCTCCAGTGTCTCCTCAAAAGGATCAGATCCCTTTGGAACC
TTAGATCCCTTCGGAAGTGGGTCCTTCAATAGTGCTGAAGGCTTTGCCGACTTCAGCCAGATGTCCAAGCCCCCACCTTCTGGCCCTTTC
ACCTCCTCCTTGGGAGGGGCAGGATTCTCAGATGACCCCTTTAAAAGTAAACAGGACACTCCTGCTCTGCCTCCGAAGAAACCTGCTCCT
CCACGGCCTAAACCGCCCAGCGGTAAAAGTACACCTGTAAGCCAGCTTGGTTCCGCAGACTTTCCCGAGGCCCCCGATCCATTCCAGCCA
CTCGGGGCTGACAGCGGCGACCCGTTCCAAAGTAAAAAGGGGTTTGGGGACCCGTTTAGTGGAAAAGACCCATTTGTCCCCTCCTCTGCA
GCTAAACCTTCTAAGGCCTCTGCCTCGGGCTTTGCAGACTTCACCTCTGTAAGTTGAGTCCTCCGCCTCCGGGCCACCCCACTCCCTTCC
GCTTGCAGCTTCCCTGGGATTTTTGTCTCCTTTTAAAGGCAAACCTCCCAGCTTCTTTAGCCTCTTGGTACCTCACACTCTCTGTCCCTC

>In-frame_AKAP8L_ENST00000397410_chr19_15529722_-_EPS15L1_ENST00000535753_chr19_16532287_-_1987nt
GAGCCAATGCGGTCGGGAGGCGGGGCTCGGGTGTGTGTGGAGGGGACCCTGTGGTTAGCAGCAGCTATCGCAGCGTCGGATGTTCAGAGC
AGCAGAAGCCGGCGTCGTCGGATGTTGTGTTGCCCGCCACCATGAGCTACACAGCCAACAGTGAACTGGGTGGTGCCCGTGGCAGACAAG
ATGCGATTTGATGAGATATTCCTGAAGACCGACCTGGACCTGGATGGCTACGTGAGTGGCCAGGAGGTGAAGGAGATCTTCATGCACTCG
GGCCTCACCCAGAACCTTCTAGCACACATATGGGCCCTGGCCGATACGAGGCAAACGGGGAAGTTAAGCAAAGACCAATTCGCGTTAGCT
ATGTATTTCATTCAGCAGAAGGTCAGTAAAGGCATCGACCCTCCTCAAGTCCTCTCGCCGGACATGGTCCCGCCTTCGGAGAGAGGCACG
CCCGGCCCGGACAGTTCAGGCTCTCTCGGCTCCGGGGAGTTTACTGGCGTGAAGGAGCTTGATGACATCAGTCAAGAGATTGCCCAGTTA
CAAAGAGAGAAATATTCACTGGAACAAGACATTCGAGAAAAGGAAGAGGCAATCAGACAGAAAACCAGCGAGGTGCAGGAATTACAAAAT
GACCTAGACCGGGAAACAAGCAGTTTGCAGGAGCTCGAGGCTCAGAAACAGGATGCTCAAGACCGCCTGGACGAGATGGACCAGCAGAAG
GCCAAGCTCCGAGACATGCTGAGCGACGTCCGGCAGAAGTGCCAGGATGAGACTCAGATGATCTCATCACTGAAAACGCAAATCCAATCT
CAGGAATCTGACTTAAAGTCCCAGGAAGACGATCTGAACCGAGCCAAGTCGGAGCTGAACCGATTGCAGCAGGAGGAAACCCAGCTGGAG
CAGAGCATTCAGGCTGGGCGAGTCCAGCTGGAAACCATCATCAAGTCCCTGAAGTCAACGCAAGACGAAATCAACCAGGCAAGGAGCAAA
CTTTCCCAGCTGCATGAAAGCCGCCAGGAGGCCCACAGGAGCCTGGAGCAGTATGACCAGGTGCTCGATGGAGCCCATGGTGCCAGCCTG
ACCGACCTGGCCAACCTGAGCGAAGGCGTCTCCCTGGCAGAGAGGGGCAGTTTTGGAGCCATGGATGATCCTTTCAAAAATAAAGCCTTG
TTATTTAGCAACAACACGCAAGAGTTGCATCCGGATCCTTTCCAGACAGAAGACCCCTTCAAATCTGACCCATTTAAAGGAGCTGACCCC
TTCAAAGGCGACCCGTTCCAGAATGACCCCTTTGCAGAACAGCAGACAACTTCAACAGATCCATTTGGAGGGGACCCTTTCAAAGAAAGT
GACCCATTCCGTGGCTCTGCCACTGACGACTTCTTCAAGAAACAGACAAAGAATGACCCATTTACCTCGGATCCATTCACGAAAAACCCT
TCCTTACCTTCGAAGCTCGACCCCTTTGAATCCAGTGATCCCTTTTCATCCTCCAGTGTCTCCTCAAAAGGATCAGATCCCTTTGGAACC
TTAGATCCCTTCGGAAGTGGGTCCTTCAATAGTGCTGAAGGCTTTGCCGACTTCAGCCAGATGTCCAAGGTAAAAGTACACCTGTAAGCC
AGCTTGGTTCCGCAGACTTTCCCGAGGCCCCCGATCCATTCCAGCCACTCGGGGCTGACAGCGGCGACCCGTTCCAAAGTAAAAAGGGGT
TTGGGGACCCGTTTAGTGGAAAAGACCCATTTGTCCCCTCCTCTGCAGCTAAACCTTCTAAGGCCTCTGCCTCGGGCTTTGCAGACTTCA
CCTCTGTAAGTTGAGTCCTCCGCCTCCGGGCCACCCCACTCCCTTCCGCTTGCAGCTTCCCTGGGATTTTTGTCTCCTTTTAAAGGCAAA
CCTCCCAGCTTCTTTAGCCTCTTGGTACCTCACACTCTCTGTCCCTCGCGTTATTTATTCTACACTGCCACTTCTGTAAGAAAAACAGTT

>In-frame_AKAP8L_ENST00000397410_chr19_15529722_-_EPS15L1_ENST00000594975_chr19_16532287_-_1701nt
GAGCCAATGCGGTCGGGAGGCGGGGCTCGGGTGTGTGTGGAGGGGACCCTGTGGTTAGCAGCAGCTATCGCAGCGTCGGATGTTCAGAGC
AGCAGAAGCCGGCGTCGTCGGATGTTGTGTTGCCCGCCACCATGAGCTACACAGCCAACAGTGAACTGGGTGGTGCCCGTGGCAGACAAG
ATGCGATTTGATGAGATATTCCTGAAGACCGACCTGGACCTGGATGGCTACGTGAGTGGCCAGGAGGTGAAGGAGATCTTCATGCACTCG
GGCCTCACCCAGAACCTTCTAGCACACATATGGGCCCTGGCCGATACGAGGCAAACGGGGAAGTTAAGCAAAGACCAATTCGCGTTAGCT
ATGTATTTCATTCAGCAGAAGGTCAGTAAAGGCATCGACCCTCCTCAAGTCCTCTCGCCGGACATGGTCCCGCCTTCGGAGAGAGGCACG
CCCGGCCCGGACAGTTCAGGCTCTCTCGGCTCCGGGGAGTTTACTGGCGTGAAGGAGCTTGATGACATCAGTCAAGAGATTGCCCAGTTA
CAAAGAGAGAAATATTCACTGGAACAAGACATTCGAGAAAAGGAAGAGGCAATCAGACAGAAAACCAGCGAGGTGCAGGAATTACAAAAT
GACCTAGACCGGGAAACAAGCAGTTTGCAGGAGCTCGAGGCTCAGAAACAGGATGCTCAAGACCGCCTGGACGAGATGGACCAGCAGAAG
GCCAAGCTCCGAGACATGCTGAGCGACGTCCGGCAGAAGTGCCAGGATGAGACTCAGATGATCTCATCACTGAAAACGCAAATCCAATCT
CAGGAATCTGACTTAAAGTCCCAGGAAGACGATCTGAACCGAGCCAAGTCGGAGCTGAACCGATTGCAGCAGGAGGAAACCCAGCTGGAG
CAGAGCATTCAGGCTGGGCGAGTCCAGCTGGAAACCATCATCAAGTCCCTGAAGTCAACGCAAGACGAAATCAACCAGGCAAGGAGCAAA
CTTTCCCAGCTGCATGAAAGCCGCCAGGAGGCCCACAGGAGCCTGGAGCAGTATGACCAGGTGCTCGATGGAGCCCATGGTGCCAGCCTG
ACCGACCTGGCCAACCTGAGCGAAGGCGTCTCCCTGGCAGAGAGGGGCAGTTTTGGAGCCATGGTAAAGGATGATCCTTTCAAAAATAAA
GCCTTGTTATTTAGCAACAACACGCAAGAGTTGCATCCGGATCCTTTCCAGACAGAAGACCCCTTCAAATCTGACCCATTTAAAGGAGCT
GACCCCTTCAAAGGCGACCCGTTCCAGAATGACCCCTTTGCAGAACAGCAGACAACTTCAACAGATCCATTTGGAGGGGACCCTTTCAAA
GAAAGTGACCCATTCCGTGGCTCTGCCACTGACGACTTCTTCAAGAAACAGACAAAGAATGACCCATTTACCTCGGATCCATTCACGAAA
AACCCTTCCTTACCTTCGAAGCTCGACCCCTTTGAATCCAGTGATCCCTTTTCATCCTCCAGTGTCTCCTCAAAAGGATCAGATCCCTTT
GGAACCTTAGATCCCTTCGGAAGTGGGTCCTTCAATAGTGCTGAAGGCTTTGCCGACTTCAGCCAGATGTCCAAGGTAAAAGTACACCTG

>In-frame_AKAP8L_ENST00000397410_chr19_15529722_-_EPS15L1_ENST00000602009_chr19_16532287_-_2833nt
GAGCCAATGCGGTCGGGAGGCGGGGCTCGGGTGTGTGTGGAGGGGACCCTGTGGTTAGCAGCAGCTATCGCAGCGTCGGATGTTCAGAGC
AGCAGAAGCCGGCGTCGTCGGATGTTGTGTTGCCCGCCACCATGAGCTACACAGCCAACAGTGAACTGGGTGGTGCCCGTGGCAGACAAG
ATGCGATTTGATGAGATATTCCTGAAGACCGACCTGGACCTGGATGGCTACGTGAGTGGCCAGGAGGTGAAGGAGATCTTCATGCACTCG
GGCCTCACCCAGAACCTTCTAGCACACATATGGGCCCTGGCCGATACGAGGCAAACGGGGAAGTTAAGCAAAGACCAATTCGCGTTAGCT
ATGTATTTCATTCAGCAGAAGGTCAGTAAAGGCATCGACCCTCCTCAAGTCCTCTCGCCGGACATGGTCCCGCCTTCGGAGAGAGGCACG
CCCGGCCCGGACAGTTCAGGCTCTCTCGGCTCCGGGGAGTTTACTGGCGTGAAGGAGCTTGATGACATCAGTCAAGAGATTGCCCAGTTA
CAAAGAGAGAAATATTCACTGGAACAAGACATTCGAGAAAAGGAAGAGGCAATCAGACAGAAAACCAGCGAGGTGCAGGAATTACAAAAT
GACCTAGACCGGGAAACAAGCAGTTTGCAGGAGCTCGAGGCTCAGAAACAGGATGCTCAAGACCGCCTGGACGAGATGGACCAGCAGAAG
GCCAAGCTCCGAGACATGCTGAGCGACGTCCGGCAGAAGTGCCAGGATGAGACTCAGATGATCTCATCACTGAAAACGCAAATCCAATCT
CAGGAATCTGACTTAAAGTCCCAGGAAGACGATCTGAACCGAGCCAAGTCGGAGCTGAACCGATTGCAGCAGGAGGAAACCCAGCTGGAG
CAGAGCATTCAGGCTGGGCGAGTCCAGCTGGAAACCATCATCAAGTCCCTGAAGTCAACGCAAGACGAAATCAACCAGGCAAGGAGCAAA
CTTTCCCAGCTGCATGAAAGCCGCCAGGAGGCCCACAGGAGCCTGGAGCAGTATGACCAGGTGCTCGATGGAGCCCATGGTGCCAGCCTG
ACCGACCTGGCCAACCTGAGCGAAGGCGTCTCCCTGGCAGAGAGGGGCAGTTTTGGAGCCATGGTAAAGGTTGAATAAACGTATTACAGT
ATGGGGCTCTGGTCCCCTGGTGTGACAGCAGAACATCCCACCCGCCAGATCTGTTCATGGCCAACGTTGGTTCCAGCCAAGTGCAGGCGG
CTGTCTGTTGTTTTTGCTGCCACTTTGCGCGTTCACACCAGGCCTTGCAGCCTGGCACAGGTGGCCATGCTGAATCCTGGCTTCCAGAAC
AAAGTCCAAGATAGGCCTGGATCCTTTCAGAACCTGTTTTGAATGCCCTCCATCTCTGCGGAAGTATTTACATTGGGCCAACCACCCAAG
TTCAGAGGGCTTCTCAAACTTAACCAAAATTGGATCAGTTTCTGCTCATTGTGGAAACCCCACATTCTACTAATCAGGGGGCAGGGGACA
TCTGAGGGGCATGTGTCTATGTGTATGTGTGTTTCCACAAGGAACACCTTGAAAAGCAAATGTGTTGCTAAAGATGAGGAAGTAATGGCA
AGCAGCGCCCCAGGGTGTTGCTCTTTCAAGTAAGAATTGGCCTCTCCTGAAATTTTGGTTATGTTTAAAAACCTCTGCACTTTACTCTGA
CCTCATGACCCTGGAGTTGTGATCAGGCCTGGGGCAGGGGACTGTCGGCCCCTTACATTTTTGAGAGCTCTTGAGCCCCTGATACCAAGA
CAGGTGTGACCTTTTCCTTAGGTGGTCACATCCCCCCTGTTCACACCAGAGTCTGCCCCTGCAGCCTCGAACCTGGGGACATGTAGTTTC
CCATTTCGTCTTGGTGCTGTTCCGGGAGCGGATGGGCCGGGCCGCGCATGTCTGGATGTTTCCTTGGTGCTCTGCTGCCTCCAGCAGCTC
TCTCCGTGCTGCCACCCTCTCTCCCAGGGCTCCTCCCTGGAGCCCTTCTGCTCCTGGGCCTCTGTACGTCATGGATTCCTCTTCCTCCCT
GGAATAAGAGTGAGCGCTCGTGCTCTCTAAACACCACACTTGCCTCTTTATGTTCAATGCTTGATGTGTTTCTTTTCTCAGCAGCCAAGT
CCTCAGTCCCAAGGATTTATGGGGAAGCACACGCGTCCCCTGGGCTGCTGGGAAGGCACTGCTGGCGAGCTCATCTGTCTCTTGTGTCTG
GCCCCCGCTGGGTGCACCGCCTCCCTCTTTCCTCCCATACTCTCTTTTCTCGTGGACTCGTAATGAGGTGGTTTCCATAGCCGCCCCCGG
GCCCGTCATCATCAGCTTTATCGTCTAAATTTAAACGATGAGCATTCATCCTTCATGAGTTACGAGAAGCCAGAACTCCTCGCTTTGCTC
CCTGGCTGTTCTTGGCGTGTGTGTTTCCGTCTCACAACCCGGCTCCTACTTTCCCCATCTGGCATTGTCCCCTGGCACCGCTTTTGGCTT
GTCCTGCTCAGTCTTCGTTCAGGGAACAGCTTCCTCTTAAATGTCCCTTTTGCAGGTTTTTAGAAACCGGTTTTCTTGGATAAAAGTTGG
CAGTGAAGTGGCAGTTTGCAAGTGGCCAGTGATTCCCCCAACTCCAAAGACAGATTTTTACCTTTCTGGTTATTTTTGTTCATCTTTTGG
GCAGGGCAAAGGTTACCTGAGACACAATTACTTTGGGAATGTAGATTAAGATACGTTACATGGAAACTTGCAACTGGCATCCGAAAGAAA

>In-frame_AKAP8L_ENST00000397410_chr19_15529722_-_EPS15L1_ENST00000597937_chr19_16532287_-_2833nt
GAGCCAATGCGGTCGGGAGGCGGGGCTCGGGTGTGTGTGGAGGGGACCCTGTGGTTAGCAGCAGCTATCGCAGCGTCGGATGTTCAGAGC
AGCAGAAGCCGGCGTCGTCGGATGTTGTGTTGCCCGCCACCATGAGCTACACAGCCAACAGTGAACTGGGTGGTGCCCGTGGCAGACAAG
ATGCGATTTGATGAGATATTCCTGAAGACCGACCTGGACCTGGATGGCTACGTGAGTGGCCAGGAGGTGAAGGAGATCTTCATGCACTCG
GGCCTCACCCAGAACCTTCTAGCACACATATGGGCCCTGGCCGATACGAGGCAAACGGGGAAGTTAAGCAAAGACCAATTCGCGTTAGCT
ATGTATTTCATTCAGCAGAAGGTCAGTAAAGGCATCGACCCTCCTCAAGTCCTCTCGCCGGACATGGTCCCGCCTTCGGAGAGAGGCACG
CCCGGCCCGGACAGTTCAGGCTCTCTCGGCTCCGGGGAGTTTACTGGCGTGAAGGAGCTTGATGACATCAGTCAAGAGATTGCCCAGTTA
CAAAGAGAGAAATATTCACTGGAACAAGACATTCGAGAAAAGGAAGAGGCAATCAGACAGAAAACCAGCGAGGTGCAGGAATTACAAAAT
GACCTAGACCGGGAAACAAGCAGTTTGCAGGAGCTCGAGGCTCAGAAACAGGATGCTCAAGACCGCCTGGACGAGATGGACCAGCAGAAG
GCCAAGCTCCGAGACATGCTGAGCGACGTCCGGCAGAAGTGCCAGGATGAGACTCAGATGATCTCATCACTGAAAACGCAAATCCAATCT
CAGGAATCTGACTTAAAGTCCCAGGAAGACGATCTGAACCGAGCCAAGTCGGAGCTGAACCGATTGCAGCAGGAGGAAACCCAGCTGGAG
CAGAGCATTCAGGCTGGGCGAGTCCAGCTGGAAACCATCATCAAGTCCCTGAAGTCAACGCAAGACGAAATCAACCAGGCAAGGAGCAAA
CTTTCCCAGCTGCATGAAAGCCGCCAGGAGGCCCACAGGAGCCTGGAGCAGTATGACCAGGTGCTCGATGGAGCCCATGGTGCCAGCCTG
ACCGACCTGGCCAACCTGAGCGAAGGCGTCTCCCTGGCAGAGAGGGGCAGTTTTGGAGCCATGGTAAAGGTTGAATAAACGTATTACAGT
ATGGGGCTCTGGTCCCCTGGTGTGACAGCAGAACATCCCACCCGCCAGATCTGTTCATGGCCAACGTTGGTTCCAGCCAAGTGCAGGCGG
CTGTCTGTTGTTTTTGCTGCCACTTTGCGCGTTCACACCAGGCCTTGCAGCCTGGCACAGGTGGCCATGCTGAATCCTGGCTTCCAGAAC
AAAGTCCAAGATAGGCCTGGATCCTTTCAGAACCTGTTTTGAATGCCCTCCATCTCTGCGGAAGTATTTACATTGGGCCAACCACCCAAG
TTCAGAGGGCTTCTCAAACTTAACCAAAATTGGATCAGTTTCTGCTCATTGTGGAAACCCCACATTCTACTAATCAGGGGGCAGGGGACA
TCTGAGGGGCATGTGTCTATGTGTATGTGTGTTTCCACAAGGAACACCTTGAAAAGCAAATGTGTTGCTAAAGATGAGGAAGTAATGGCA
AGCAGCGCCCCAGGGTGTTGCTCTTTCAAGTAAGAATTGGCCTCTCCTGAAATTTTGGTTATGTTTAAAAACCTCTGCACTTTACTCTGA
CCTCATGACCCTGGAGTTGTGATCAGGCCTGGGGCAGGGGACTGTCGGCCCCTTACATTTTTGAGAGCTCTTGAGCCCCTGATACCAAGA
CAGGTGTGACCTTTTCCTTAGGTGGTCACATCCCCCCTGTTCACACCAGAGTCTGCCCCTGCAGCCTCGAACCTGGGGACATGTAGTTTC
CCATTTCGTCTTGGTGCTGTTCCGGGAGCGGATGGGCCGGGCCGCGCATGTCTGGATGTTTCCTTGGTGCTCTGCTGCCTCCAGCAGCTC
TCTCCGTGCTGCCACCCTCTCTCCCAGGGCTCCTCCCTGGAGCCCTTCTGCTCCTGGGCCTCTGTACGTCATGGATTCCTCTTCCTCCCT
GGAATAAGAGTGAGCGCTCGTGCTCTCTAAACACCACACTTGCCTCTTTATGTTCAATGCTTGATGTGTTTCTTTTCTCAGCAGCCAAGT
CCTCAGTCCCAAGGATTTATGGGGAAGCACACGCGTCCCCTGGGCTGCTGGGAAGGCACTGCTGGCGAGCTCATCTGTCTCTTGTGTCTG
GCCCCCGCTGGGTGCACCGCCTCCCTCTTTCCTCCCATACTCTCTTTTCTCGTGGACTCGTAATGAGGTGGTTTCCATAGCCGCCCCCGG
GCCCGTCATCATCAGCTTTATCGTCTAAATTTAAACGATGAGCATTCATCCTTCATGAGTTACGAGAAGCCAGAACTCCTCGCTTTGCTC
CCTGGCTGTTCTTGGCGTGTGTGTTTCCGTCTCACAACCCGGCTCCTACTTTCCCCATCTGGCATTGTCCCCTGGCACCGCTTTTGGCTT
GTCCTGCTCAGTCTTCGTTCAGGGAACAGCTTCCTCTTAAATGTCCCTTTTGCAGGTTTTTAGAAACCGGTTTTCTTGGATAAAAGTTGG
CAGTGAAGTGGCAGTTTGCAAGTGGCCAGTGATTCCCCCAACTCCAAAGACAGATTTTTACCTTTCTGGTTATTTTTGTTCATCTTTTGG
GCAGGGCAAAGGTTACCTGAGACACAATTACTTTGGGAATGTAGATTAAGATACGTTACATGGAAACTTGCAACTGGCATCCGAAAGAAA

>In-frame_AKAP8L_ENST00000595465_chr19_15529722_-_EPS15L1_ENST00000455140_chr19_16532287_-_2523nt
GGGTGTGTGTGGAGGGGACCCTGTGGTTAGCAGCAGCTATCGCAGCGTCGGATGTTCAGAGCAGCAGAAGCCGGCGTCGTCGGATGTTGT
GTTGCCCGCCACCATGAGCTACACAGCCAACAGTGAACTGGGTGGTGCCCGTGGCAGACAAGATGCGATTTGATGAGATATTCCTGAAGA
CCGACCTGGACCTGGATGGCTACGTGAGTGGCCAGGAGGTGAAGGAGATCTTCATGCACTCGGGCCTCACCCAGAACCTTCTAGCACACA
TATGGGCCCTGGCCGATACGAGGCAAACGGGGAAGTTAAGCAAAGACCAATTCGCGTTAGCTATGTATTTCATTCAGCAGAAGGTCAGTA
AAGGCATCGACCCTCCTCAAGTCCTCTCGCCGGACATGGTCCCGCCTTCGGAGAGAGGCACGCCCGGCCCGGACAGTTCAGGCTCTCTCG
GCTCCGGGGAGTTTACTGGCGTGAAGGAGCTTGATGACATCAGTCAAGAGATTGCCCAGTTACAAAGAGAGAAATATTCACTGGAACAAG
ACATTCGAGAAAAGGAAGAGGCAATCAGACAGAAAACCAGCGAGGTGCAGGAATTACAAAATGACCTAGACCGGGAAACAAGCAGTTTGC
AGGAGCTCGAGGCTCAGAAACAGGATGCTCAAGACCGCCTGGACGAGATGGACCAGCAGAAGGCCAAGCTCCGAGACATGCTGAGCGACG
TCCGGCAGAAGTGCCAGGATGAGACTCAGATGATCTCATCACTGAAAACGCAAATCCAATCTCAGGAATCTGACTTAAAGTCCCAGGAAG
ACGATCTGAACCGAGCCAAGTCGGAGCTGAACCGATTGCAGCAGGAGGAAACCCAGCTGGAGCAGAGCATTCAGGCTGGGCGAGTCCAGC
TGGAAACCATCATCAAGTCCCTGAAGTCAACGCAAGACGAAATCAACCAGGCAAGGAGCAAACTTTCCCAGCTGCATGAAAGCCGCCAGG
AGGCCCACAGGAGCCTGGAGCAGTATGACCAGGTGCTCGATGGAGCCCATGGTGCCAGCCTGACCGACCTGGCCAACCTGAGCGAAGGCG
TCTCCCTGGCAGAGAGGGGCAGTTTTGGAGCCATGGATGATCCTTTCAAAAATAAAGCCTTGTTATTTAGCAACAACACGCAAGAGTTGC
ATCCGGATCCTTTCCAGACAGAAGACCCCTTCAAATCTGACCCATTTAAAGGAGCTGACCCCTTCAAAGGCGACCCGTTCCAGAATGACC
CCTTTGCAGAACAGCAGACAACTTCAACAGATCCATTTGGAGGGGACCCTTTCAAAGAAAGTGACCCATTCCGTGGCTCTGCCACTGACG
ACTTCTTCAAGAAACAGACAAAGAATGACCCATTTACCTCGGATCCATTCACGAAAAACCCTTCCTTACCTTCGAAGCTCGACCCCTTTG
AATCCAGTGATCCCTTTTCATCCTCCAGTGTCTCCTCAAAAGGATCAGATCCCTTTGGAACCTTAGATCCCTTCGGAAGTGGGTCCTTCA
ATAGTGCTGAAGGCTTTGCCGACTTCAGCCAGATGTCCAAGCCCCCACCTTCTGGCCCTTTCACCTCCTCCTTGGGAGGGGCAGGATTCT
CAGATGACCCCTTTAAAAGTAAACAGGACACTCCTGCTCTGCCTCCGAAGAAACCTGCTCCTCCACGGCCTAAACCGCCCAGCGGTAAAA
GTACACCTGTAAGCCAGCTTGGTTCCGCAGACTTTCCCGAGGCCCCCGATCCATTCCAGCCACTCGGGGCTGACAGCGGCGACCCGTTCC
AAAGTAAAAAGGGGTTTGGGGACCCGTTTAGTGGAAAAGACCCATTTGTCCCCTCCTCTGCAGCTAAACCTTCTAAGGCCTCTGCCTCGG
GCTTTGCAGACTTCACCTCTTTTGGCAATGAGGAGCAGCAGCTGGCGTGGGCCAAGCGGGAGAGCGAGAAGGCGGAACAGGAGAGGCTGG
CGCGGCTGCGGCGGCAGGAGCAGGAGGACCTGGAACTGGCCATCGCGCTCAGCAAGGCTGACATGCCTGCCGCCTAGGCGAGGGCCGTGT
GTAGGCGGGACAGGGCACGGGCGGGTTCCAGAGAGGGGGCAGTGCAGATGTCTATATATACACACACACACCGTCGCCACCGTACTCCAA
GGACCGGGACTCGGGGGCTTGTTCAGGGTGAGCAGACTCGGCTGCAAGACCTGGAAAGGTCACATCTCCTGGGGAAGCCCTTACAGAGGC
CTTGGCCACCACTTCTGCAGGTCCGTCTCTCCACTGTGCCATCCCCCCCGGGGCTGACTGCCTCCCGCTCTTCCTCTGGGGACGAACACA
CAGCGGTCAGTCGAGGAGAGGAAGCACCCAGGGCTTCCCCGCCTCCTCCCTACTCATAGCTGCAGACATCCCCACCCGCCCTCCCACGCA
TCAGTCAGACACTCCCCCAGTGGTGTATGCACTCGTTGTATAAAATGAAGTTTGAATGATTAATATAAAATATTTTAATACAAAACAAGA

>In-frame_AKAP8L_ENST00000595465_chr19_15529722_-_EPS15L1_ENST00000248070_chr19_16532287_-_2108nt
GGGTGTGTGTGGAGGGGACCCTGTGGTTAGCAGCAGCTATCGCAGCGTCGGATGTTCAGAGCAGCAGAAGCCGGCGTCGTCGGATGTTGT
GTTGCCCGCCACCATGAGCTACACAGCCAACAGTGAACTGGGTGGTGCCCGTGGCAGACAAGATGCGATTTGATGAGATATTCCTGAAGA
CCGACCTGGACCTGGATGGCTACGTGAGTGGCCAGGAGGTGAAGGAGATCTTCATGCACTCGGGCCTCACCCAGAACCTTCTAGCACACA
TATGGGCCCTGGCCGATACGAGGCAAACGGGGAAGTTAAGCAAAGACCAATTCGCGTTAGCTATGTATTTCATTCAGCAGAAGGTCAGTA
AAGGCATCGACCCTCCTCAAGTCCTCTCGCCGGACATGGTCCCGCCTTCGGAGAGAGGCACGCCCGGCCCGGACAGTTCAGGCTCTCTCG
GCTCCGGGGAGTTTACTGGCGTGAAGGAGCTTGATGACATCAGTCAAGAGATTGCCCAGTTACAAAGAGAGAAATATTCACTGGAACAAG
ACATTCGAGAAAAGGAAGAGGCAATCAGACAGAAAACCAGCGAGGTGCAGGAATTACAAAATGACCTAGACCGGGAAACAAGCAGTTTGC
AGGAGCTCGAGGCTCAGAAACAGGATGCTCAAGACCGCCTGGACGAGATGGACCAGCAGAAGGCCAAGCTCCGAGACATGCTGAGCGACG
TCCGGCAGAAGTGCCAGGATGAGACTCAGATGATCTCATCACTGAAAACGCAAATCCAATCTCAGGAATCTGACTTAAAGTCCCAGGAAG
ACGATCTGAACCGAGCCAAGTCGGAGCTGAACCGATTGCAGCAGGAGGAAACCCAGCTGGAGCAGAGCATTCAGGCTGGGCGAGTCCAGC
TGGAAACCATCATCAAGTCCCTGAAGTCAACGCAAGACGAAATCAACCAGGCAAGGAGCAAACTTTCCCAGCTGCATGAAAGCCGCCAGG
AGGCCCACAGGAGCCTGGAGCAGTATGACCAGGTGCTCGATGGAGCCCATGGTGCCAGCCTGACCGACCTGGCCAACCTGAGCGAAGGCG
TCTCCCTGGCAGAGAGGGGCAGTTTTGGAGCCATGGATGATCCTTTCAAAAATAAAGCCTTGTTATTTAGCAACAACACGCAAGAGTTGC
ATCCGGATCCTTTCCAGACAGAAGACCCCTTCAAATCTGACCCATTTAAAGGAGCTGACCCCTTCAAAGGCGACCCGTTCCAGAATGACC
CCTTTGCAGAACAGCAGACAACTTCAACAGATCCATTTGGAGGGGACCCTTTCAAAGAAAGTGACCCATTCCGTGGCTCTGCCACTGACG
ACTTCTTCAAGAAACAGACAAAGAATGACCCATTTACCTCGGATCCATTCACGAAAAACCCTTCCTTACCTTCGAAGCTCGACCCCTTTG
AATCCAGTGATCCCTTTTCATCCTCCAGTGTCTCCTCAAAAGGATCAGATCCCTTTGGAACCTTAGATCCCTTCGGAAGTGGGTCCTTCA
ATAGTGCTGAAGGCTTTGCCGACTTCAGCCAGATGTCCAAGCCCCCACCTTCTGGCCCTTTCACCTCCTCCTTGGGAGGGGCAGGATTCT
CAGATGACCCCTTTAAAAGTAAACAGGACACTCCTGCTCTGCCTCCGAAGAAACCTGCTCCTCCACGGCCTAAACCGCCCAGCGGTAAAA
GTACACCTGTAAGCCAGCTTGGTTCCGCAGACTTTCCCGAGGCCCCCGATCCATTCCAGCCACTCGGGGCTGACAGCGGCGACCCGTTCC
AAAGTAAAAAGGGGTTTGGGGACCCGTTTAGTGGAAAAGACCCATTTGTCCCCTCCTCTGCAGCTAAACCTTCTAAGGCCTCTGCCTCGG
GCTTTGCAGACTTCACCTCTGTAAGTTGAGTCCTCCGCCTCCGGGCCACCCCACTCCCTTCCGCTTGCAGCTTCCCTGGGATTTTTGTCT
CCTTTTAAAGGCAAACCTCCCAGCTTCTTTAGCCTCTTGGTACCTCACACTCTCTGTCCCTCGCGTTATTTATTCTACACTGCCACTTCT

>In-frame_AKAP8L_ENST00000595465_chr19_15529722_-_EPS15L1_ENST00000535753_chr19_16532287_-_1959nt
GGGTGTGTGTGGAGGGGACCCTGTGGTTAGCAGCAGCTATCGCAGCGTCGGATGTTCAGAGCAGCAGAAGCCGGCGTCGTCGGATGTTGT
GTTGCCCGCCACCATGAGCTACACAGCCAACAGTGAACTGGGTGGTGCCCGTGGCAGACAAGATGCGATTTGATGAGATATTCCTGAAGA
CCGACCTGGACCTGGATGGCTACGTGAGTGGCCAGGAGGTGAAGGAGATCTTCATGCACTCGGGCCTCACCCAGAACCTTCTAGCACACA
TATGGGCCCTGGCCGATACGAGGCAAACGGGGAAGTTAAGCAAAGACCAATTCGCGTTAGCTATGTATTTCATTCAGCAGAAGGTCAGTA
AAGGCATCGACCCTCCTCAAGTCCTCTCGCCGGACATGGTCCCGCCTTCGGAGAGAGGCACGCCCGGCCCGGACAGTTCAGGCTCTCTCG
GCTCCGGGGAGTTTACTGGCGTGAAGGAGCTTGATGACATCAGTCAAGAGATTGCCCAGTTACAAAGAGAGAAATATTCACTGGAACAAG
ACATTCGAGAAAAGGAAGAGGCAATCAGACAGAAAACCAGCGAGGTGCAGGAATTACAAAATGACCTAGACCGGGAAACAAGCAGTTTGC
AGGAGCTCGAGGCTCAGAAACAGGATGCTCAAGACCGCCTGGACGAGATGGACCAGCAGAAGGCCAAGCTCCGAGACATGCTGAGCGACG
TCCGGCAGAAGTGCCAGGATGAGACTCAGATGATCTCATCACTGAAAACGCAAATCCAATCTCAGGAATCTGACTTAAAGTCCCAGGAAG
ACGATCTGAACCGAGCCAAGTCGGAGCTGAACCGATTGCAGCAGGAGGAAACCCAGCTGGAGCAGAGCATTCAGGCTGGGCGAGTCCAGC
TGGAAACCATCATCAAGTCCCTGAAGTCAACGCAAGACGAAATCAACCAGGCAAGGAGCAAACTTTCCCAGCTGCATGAAAGCCGCCAGG
AGGCCCACAGGAGCCTGGAGCAGTATGACCAGGTGCTCGATGGAGCCCATGGTGCCAGCCTGACCGACCTGGCCAACCTGAGCGAAGGCG
TCTCCCTGGCAGAGAGGGGCAGTTTTGGAGCCATGGATGATCCTTTCAAAAATAAAGCCTTGTTATTTAGCAACAACACGCAAGAGTTGC
ATCCGGATCCTTTCCAGACAGAAGACCCCTTCAAATCTGACCCATTTAAAGGAGCTGACCCCTTCAAAGGCGACCCGTTCCAGAATGACC
CCTTTGCAGAACAGCAGACAACTTCAACAGATCCATTTGGAGGGGACCCTTTCAAAGAAAGTGACCCATTCCGTGGCTCTGCCACTGACG
ACTTCTTCAAGAAACAGACAAAGAATGACCCATTTACCTCGGATCCATTCACGAAAAACCCTTCCTTACCTTCGAAGCTCGACCCCTTTG
AATCCAGTGATCCCTTTTCATCCTCCAGTGTCTCCTCAAAAGGATCAGATCCCTTTGGAACCTTAGATCCCTTCGGAAGTGGGTCCTTCA
ATAGTGCTGAAGGCTTTGCCGACTTCAGCCAGATGTCCAAGGTAAAAGTACACCTGTAAGCCAGCTTGGTTCCGCAGACTTTCCCGAGGC
CCCCGATCCATTCCAGCCACTCGGGGCTGACAGCGGCGACCCGTTCCAAAGTAAAAAGGGGTTTGGGGACCCGTTTAGTGGAAAAGACCC
ATTTGTCCCCTCCTCTGCAGCTAAACCTTCTAAGGCCTCTGCCTCGGGCTTTGCAGACTTCACCTCTGTAAGTTGAGTCCTCCGCCTCCG
GGCCACCCCACTCCCTTCCGCTTGCAGCTTCCCTGGGATTTTTGTCTCCTTTTAAAGGCAAACCTCCCAGCTTCTTTAGCCTCTTGGTAC

>In-frame_AKAP8L_ENST00000595465_chr19_15529722_-_EPS15L1_ENST00000594975_chr19_16532287_-_1673nt
GGGTGTGTGTGGAGGGGACCCTGTGGTTAGCAGCAGCTATCGCAGCGTCGGATGTTCAGAGCAGCAGAAGCCGGCGTCGTCGGATGTTGT
GTTGCCCGCCACCATGAGCTACACAGCCAACAGTGAACTGGGTGGTGCCCGTGGCAGACAAGATGCGATTTGATGAGATATTCCTGAAGA
CCGACCTGGACCTGGATGGCTACGTGAGTGGCCAGGAGGTGAAGGAGATCTTCATGCACTCGGGCCTCACCCAGAACCTTCTAGCACACA
TATGGGCCCTGGCCGATACGAGGCAAACGGGGAAGTTAAGCAAAGACCAATTCGCGTTAGCTATGTATTTCATTCAGCAGAAGGTCAGTA
AAGGCATCGACCCTCCTCAAGTCCTCTCGCCGGACATGGTCCCGCCTTCGGAGAGAGGCACGCCCGGCCCGGACAGTTCAGGCTCTCTCG
GCTCCGGGGAGTTTACTGGCGTGAAGGAGCTTGATGACATCAGTCAAGAGATTGCCCAGTTACAAAGAGAGAAATATTCACTGGAACAAG
ACATTCGAGAAAAGGAAGAGGCAATCAGACAGAAAACCAGCGAGGTGCAGGAATTACAAAATGACCTAGACCGGGAAACAAGCAGTTTGC
AGGAGCTCGAGGCTCAGAAACAGGATGCTCAAGACCGCCTGGACGAGATGGACCAGCAGAAGGCCAAGCTCCGAGACATGCTGAGCGACG
TCCGGCAGAAGTGCCAGGATGAGACTCAGATGATCTCATCACTGAAAACGCAAATCCAATCTCAGGAATCTGACTTAAAGTCCCAGGAAG
ACGATCTGAACCGAGCCAAGTCGGAGCTGAACCGATTGCAGCAGGAGGAAACCCAGCTGGAGCAGAGCATTCAGGCTGGGCGAGTCCAGC
TGGAAACCATCATCAAGTCCCTGAAGTCAACGCAAGACGAAATCAACCAGGCAAGGAGCAAACTTTCCCAGCTGCATGAAAGCCGCCAGG
AGGCCCACAGGAGCCTGGAGCAGTATGACCAGGTGCTCGATGGAGCCCATGGTGCCAGCCTGACCGACCTGGCCAACCTGAGCGAAGGCG
TCTCCCTGGCAGAGAGGGGCAGTTTTGGAGCCATGGTAAAGGATGATCCTTTCAAAAATAAAGCCTTGTTATTTAGCAACAACACGCAAG
AGTTGCATCCGGATCCTTTCCAGACAGAAGACCCCTTCAAATCTGACCCATTTAAAGGAGCTGACCCCTTCAAAGGCGACCCGTTCCAGA
ATGACCCCTTTGCAGAACAGCAGACAACTTCAACAGATCCATTTGGAGGGGACCCTTTCAAAGAAAGTGACCCATTCCGTGGCTCTGCCA
CTGACGACTTCTTCAAGAAACAGACAAAGAATGACCCATTTACCTCGGATCCATTCACGAAAAACCCTTCCTTACCTTCGAAGCTCGACC
CCTTTGAATCCAGTGATCCCTTTTCATCCTCCAGTGTCTCCTCAAAAGGATCAGATCCCTTTGGAACCTTAGATCCCTTCGGAAGTGGGT
CCTTCAATAGTGCTGAAGGCTTTGCCGACTTCAGCCAGATGTCCAAGGTAAAAGTACACCTGTAAGCCAGCTTGGTTCCGCAGACTTTCC

>In-frame_AKAP8L_ENST00000595465_chr19_15529722_-_EPS15L1_ENST00000602009_chr19_16532287_-_2805nt
GGGTGTGTGTGGAGGGGACCCTGTGGTTAGCAGCAGCTATCGCAGCGTCGGATGTTCAGAGCAGCAGAAGCCGGCGTCGTCGGATGTTGT
GTTGCCCGCCACCATGAGCTACACAGCCAACAGTGAACTGGGTGGTGCCCGTGGCAGACAAGATGCGATTTGATGAGATATTCCTGAAGA
CCGACCTGGACCTGGATGGCTACGTGAGTGGCCAGGAGGTGAAGGAGATCTTCATGCACTCGGGCCTCACCCAGAACCTTCTAGCACACA
TATGGGCCCTGGCCGATACGAGGCAAACGGGGAAGTTAAGCAAAGACCAATTCGCGTTAGCTATGTATTTCATTCAGCAGAAGGTCAGTA
AAGGCATCGACCCTCCTCAAGTCCTCTCGCCGGACATGGTCCCGCCTTCGGAGAGAGGCACGCCCGGCCCGGACAGTTCAGGCTCTCTCG
GCTCCGGGGAGTTTACTGGCGTGAAGGAGCTTGATGACATCAGTCAAGAGATTGCCCAGTTACAAAGAGAGAAATATTCACTGGAACAAG
ACATTCGAGAAAAGGAAGAGGCAATCAGACAGAAAACCAGCGAGGTGCAGGAATTACAAAATGACCTAGACCGGGAAACAAGCAGTTTGC
AGGAGCTCGAGGCTCAGAAACAGGATGCTCAAGACCGCCTGGACGAGATGGACCAGCAGAAGGCCAAGCTCCGAGACATGCTGAGCGACG
TCCGGCAGAAGTGCCAGGATGAGACTCAGATGATCTCATCACTGAAAACGCAAATCCAATCTCAGGAATCTGACTTAAAGTCCCAGGAAG
ACGATCTGAACCGAGCCAAGTCGGAGCTGAACCGATTGCAGCAGGAGGAAACCCAGCTGGAGCAGAGCATTCAGGCTGGGCGAGTCCAGC
TGGAAACCATCATCAAGTCCCTGAAGTCAACGCAAGACGAAATCAACCAGGCAAGGAGCAAACTTTCCCAGCTGCATGAAAGCCGCCAGG
AGGCCCACAGGAGCCTGGAGCAGTATGACCAGGTGCTCGATGGAGCCCATGGTGCCAGCCTGACCGACCTGGCCAACCTGAGCGAAGGCG
TCTCCCTGGCAGAGAGGGGCAGTTTTGGAGCCATGGTAAAGGTTGAATAAACGTATTACAGTATGGGGCTCTGGTCCCCTGGTGTGACAG
CAGAACATCCCACCCGCCAGATCTGTTCATGGCCAACGTTGGTTCCAGCCAAGTGCAGGCGGCTGTCTGTTGTTTTTGCTGCCACTTTGC
GCGTTCACACCAGGCCTTGCAGCCTGGCACAGGTGGCCATGCTGAATCCTGGCTTCCAGAACAAAGTCCAAGATAGGCCTGGATCCTTTC
AGAACCTGTTTTGAATGCCCTCCATCTCTGCGGAAGTATTTACATTGGGCCAACCACCCAAGTTCAGAGGGCTTCTCAAACTTAACCAAA
ATTGGATCAGTTTCTGCTCATTGTGGAAACCCCACATTCTACTAATCAGGGGGCAGGGGACATCTGAGGGGCATGTGTCTATGTGTATGT
GTGTTTCCACAAGGAACACCTTGAAAAGCAAATGTGTTGCTAAAGATGAGGAAGTAATGGCAAGCAGCGCCCCAGGGTGTTGCTCTTTCA
AGTAAGAATTGGCCTCTCCTGAAATTTTGGTTATGTTTAAAAACCTCTGCACTTTACTCTGACCTCATGACCCTGGAGTTGTGATCAGGC
CTGGGGCAGGGGACTGTCGGCCCCTTACATTTTTGAGAGCTCTTGAGCCCCTGATACCAAGACAGGTGTGACCTTTTCCTTAGGTGGTCA
CATCCCCCCTGTTCACACCAGAGTCTGCCCCTGCAGCCTCGAACCTGGGGACATGTAGTTTCCCATTTCGTCTTGGTGCTGTTCCGGGAG
CGGATGGGCCGGGCCGCGCATGTCTGGATGTTTCCTTGGTGCTCTGCTGCCTCCAGCAGCTCTCTCCGTGCTGCCACCCTCTCTCCCAGG
GCTCCTCCCTGGAGCCCTTCTGCTCCTGGGCCTCTGTACGTCATGGATTCCTCTTCCTCCCTGGAATAAGAGTGAGCGCTCGTGCTCTCT
AAACACCACACTTGCCTCTTTATGTTCAATGCTTGATGTGTTTCTTTTCTCAGCAGCCAAGTCCTCAGTCCCAAGGATTTATGGGGAAGC
ACACGCGTCCCCTGGGCTGCTGGGAAGGCACTGCTGGCGAGCTCATCTGTCTCTTGTGTCTGGCCCCCGCTGGGTGCACCGCCTCCCTCT
TTCCTCCCATACTCTCTTTTCTCGTGGACTCGTAATGAGGTGGTTTCCATAGCCGCCCCCGGGCCCGTCATCATCAGCTTTATCGTCTAA
ATTTAAACGATGAGCATTCATCCTTCATGAGTTACGAGAAGCCAGAACTCCTCGCTTTGCTCCCTGGCTGTTCTTGGCGTGTGTGTTTCC
GTCTCACAACCCGGCTCCTACTTTCCCCATCTGGCATTGTCCCCTGGCACCGCTTTTGGCTTGTCCTGCTCAGTCTTCGTTCAGGGAACA
GCTTCCTCTTAAATGTCCCTTTTGCAGGTTTTTAGAAACCGGTTTTCTTGGATAAAAGTTGGCAGTGAAGTGGCAGTTTGCAAGTGGCCA
GTGATTCCCCCAACTCCAAAGACAGATTTTTACCTTTCTGGTTATTTTTGTTCATCTTTTGGGCAGGGCAAAGGTTACCTGAGACACAAT
TACTTTGGGAATGTAGATTAAGATACGTTACATGGAAACTTGCAACTGGCATCCGAAAGAAAAACTGTTTTTATCCTGTTGTACAAATAC

>In-frame_AKAP8L_ENST00000595465_chr19_15529722_-_EPS15L1_ENST00000597937_chr19_16532287_-_2805nt
GGGTGTGTGTGGAGGGGACCCTGTGGTTAGCAGCAGCTATCGCAGCGTCGGATGTTCAGAGCAGCAGAAGCCGGCGTCGTCGGATGTTGT
GTTGCCCGCCACCATGAGCTACACAGCCAACAGTGAACTGGGTGGTGCCCGTGGCAGACAAGATGCGATTTGATGAGATATTCCTGAAGA
CCGACCTGGACCTGGATGGCTACGTGAGTGGCCAGGAGGTGAAGGAGATCTTCATGCACTCGGGCCTCACCCAGAACCTTCTAGCACACA
TATGGGCCCTGGCCGATACGAGGCAAACGGGGAAGTTAAGCAAAGACCAATTCGCGTTAGCTATGTATTTCATTCAGCAGAAGGTCAGTA
AAGGCATCGACCCTCCTCAAGTCCTCTCGCCGGACATGGTCCCGCCTTCGGAGAGAGGCACGCCCGGCCCGGACAGTTCAGGCTCTCTCG
GCTCCGGGGAGTTTACTGGCGTGAAGGAGCTTGATGACATCAGTCAAGAGATTGCCCAGTTACAAAGAGAGAAATATTCACTGGAACAAG
ACATTCGAGAAAAGGAAGAGGCAATCAGACAGAAAACCAGCGAGGTGCAGGAATTACAAAATGACCTAGACCGGGAAACAAGCAGTTTGC
AGGAGCTCGAGGCTCAGAAACAGGATGCTCAAGACCGCCTGGACGAGATGGACCAGCAGAAGGCCAAGCTCCGAGACATGCTGAGCGACG
TCCGGCAGAAGTGCCAGGATGAGACTCAGATGATCTCATCACTGAAAACGCAAATCCAATCTCAGGAATCTGACTTAAAGTCCCAGGAAG
ACGATCTGAACCGAGCCAAGTCGGAGCTGAACCGATTGCAGCAGGAGGAAACCCAGCTGGAGCAGAGCATTCAGGCTGGGCGAGTCCAGC
TGGAAACCATCATCAAGTCCCTGAAGTCAACGCAAGACGAAATCAACCAGGCAAGGAGCAAACTTTCCCAGCTGCATGAAAGCCGCCAGG
AGGCCCACAGGAGCCTGGAGCAGTATGACCAGGTGCTCGATGGAGCCCATGGTGCCAGCCTGACCGACCTGGCCAACCTGAGCGAAGGCG
TCTCCCTGGCAGAGAGGGGCAGTTTTGGAGCCATGGTAAAGGTTGAATAAACGTATTACAGTATGGGGCTCTGGTCCCCTGGTGTGACAG
CAGAACATCCCACCCGCCAGATCTGTTCATGGCCAACGTTGGTTCCAGCCAAGTGCAGGCGGCTGTCTGTTGTTTTTGCTGCCACTTTGC
GCGTTCACACCAGGCCTTGCAGCCTGGCACAGGTGGCCATGCTGAATCCTGGCTTCCAGAACAAAGTCCAAGATAGGCCTGGATCCTTTC
AGAACCTGTTTTGAATGCCCTCCATCTCTGCGGAAGTATTTACATTGGGCCAACCACCCAAGTTCAGAGGGCTTCTCAAACTTAACCAAA
ATTGGATCAGTTTCTGCTCATTGTGGAAACCCCACATTCTACTAATCAGGGGGCAGGGGACATCTGAGGGGCATGTGTCTATGTGTATGT
GTGTTTCCACAAGGAACACCTTGAAAAGCAAATGTGTTGCTAAAGATGAGGAAGTAATGGCAAGCAGCGCCCCAGGGTGTTGCTCTTTCA
AGTAAGAATTGGCCTCTCCTGAAATTTTGGTTATGTTTAAAAACCTCTGCACTTTACTCTGACCTCATGACCCTGGAGTTGTGATCAGGC
CTGGGGCAGGGGACTGTCGGCCCCTTACATTTTTGAGAGCTCTTGAGCCCCTGATACCAAGACAGGTGTGACCTTTTCCTTAGGTGGTCA
CATCCCCCCTGTTCACACCAGAGTCTGCCCCTGCAGCCTCGAACCTGGGGACATGTAGTTTCCCATTTCGTCTTGGTGCTGTTCCGGGAG
CGGATGGGCCGGGCCGCGCATGTCTGGATGTTTCCTTGGTGCTCTGCTGCCTCCAGCAGCTCTCTCCGTGCTGCCACCCTCTCTCCCAGG
GCTCCTCCCTGGAGCCCTTCTGCTCCTGGGCCTCTGTACGTCATGGATTCCTCTTCCTCCCTGGAATAAGAGTGAGCGCTCGTGCTCTCT
AAACACCACACTTGCCTCTTTATGTTCAATGCTTGATGTGTTTCTTTTCTCAGCAGCCAAGTCCTCAGTCCCAAGGATTTATGGGGAAGC
ACACGCGTCCCCTGGGCTGCTGGGAAGGCACTGCTGGCGAGCTCATCTGTCTCTTGTGTCTGGCCCCCGCTGGGTGCACCGCCTCCCTCT
TTCCTCCCATACTCTCTTTTCTCGTGGACTCGTAATGAGGTGGTTTCCATAGCCGCCCCCGGGCCCGTCATCATCAGCTTTATCGTCTAA
ATTTAAACGATGAGCATTCATCCTTCATGAGTTACGAGAAGCCAGAACTCCTCGCTTTGCTCCCTGGCTGTTCTTGGCGTGTGTGTTTCC
GTCTCACAACCCGGCTCCTACTTTCCCCATCTGGCATTGTCCCCTGGCACCGCTTTTGGCTTGTCCTGCTCAGTCTTCGTTCAGGGAACA
GCTTCCTCTTAAATGTCCCTTTTGCAGGTTTTTAGAAACCGGTTTTCTTGGATAAAAGTTGGCAGTGAAGTGGCAGTTTGCAAGTGGCCA
GTGATTCCCCCAACTCCAAAGACAGATTTTTACCTTTCTGGTTATTTTTGTTCATCTTTTGGGCAGGGCAAAGGTTACCTGAGACACAAT
TACTTTGGGAATGTAGATTAAGATACGTTACATGGAAACTTGCAACTGGCATCCGAAAGAAAAACTGTTTTTATCCTGTTGTACAAATAC


Top

FusionGenePPI for AKAP8L_EPS15L1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page

.

check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors
AKAP8LMAGED1, RELA, DHX9, LBR, EMD, TMPO, CDC6, RNF43, MYC, CUL3, CUL2, CUL1, CAND1, BARD1, EPAS1, HDAC11, ANKRD28, RNF31, ILK, IRS4, SHMT2, MOV10, SUZ12, RNF2, BMI1, FBXW11, NTRK1, XPO1, MATR3, SEC16A, NF2, NANOG, RC3H1, ZNF746, PPEF2, TRIM25EPS15L1AGFG1, STON2, EPN1, ITSN1, ITSN2, UBQLN1, GRB2, BIRC6, GBF1, NCAPG, PRPF4, ZZEF1, AP2M1, GNG5, TRAPPC2B, MOV10, NXF1, AGFG2, SPC25, NTRK1, MED4, XPO1, PLK1, KIAA1107, CDH1, AP2S1, RUNDC3A, LSR, FCHO1, NCKIPSD, CDR2, AURKA, UBC, DCAF7, USP15, SPAG9, MCM2, MCM4, MCM6, IVNS1ABP, GTF3C4, SMC1A, GAPVD1, ANK3, SBNO1, SMC3, CDK11A, SOX4, HSF1, TRIM25, TXNIP


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
TgeneEPS15L1chr19:15529722chr19:16532287ENST00000248070-82315_368264865DAB2
TgeneEPS15L1chr19:15529722chr19:16532287ENST00000455140-82415_368264911DAB2
TgeneEPS15L1chr19:15529722chr19:16532287ENST00000535753-82215_368264755DAB2
TgeneEPS15L1chr19:15529722chr19:16532287ENST00000597937-81615_368264602DAB2


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


Top

RelatedDrugs for AKAP8L_EPS15L1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

Top

RelatedDiseases for AKAP8L_EPS15L1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource