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Fusion gene ID: 13296 |
FusionGeneSummary for FDPS_IPO9 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: FDPS_IPO9 | Fusion gene ID: 13296 | Hgene | Tgene | Gene symbol | FDPS | IPO9 | Gene ID | 2224 | 55705 |
| Gene name | farnesyl diphosphate synthase | importin 9 | |
| Synonyms | FPPS|FPS|POROK9 | Imp9 | |
| Cytomap | 1q22 | 1q32.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | farnesyl pyrophosphate synthase(2E,6E)-farnesyl diphosphate synthaseFPP synthaseFPP synthetasefarnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase | importin-9ran-binding protein 9ranBP9 | |
| Modification date | 20180523 | 20180523 | |
| UniProtAcc | P14324 | Q96P70 | |
| Ensembl transtripts involved in fusion gene | ENST00000447866, ENST00000368356, ENST00000487002, ENST00000356657, | ENST00000361565, ENST00000464348, | |
| Fusion gene scores | * DoF score | 4 X 4 X 2=32 | 5 X 5 X 3=75 |
| # samples | 4 | 5 | |
| ** MAII score | log2(4/32*10)=0.321928094887362 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | log2(5/75*10)=-0.584962500721156 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: FDPS [Title/Abstract] AND IPO9 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | PRAD | TCGA-J4-A67Q-01A | FDPS | chr1 | 155282186 | + | IPO9 | chr1 | 201840289 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000447866 | ENST00000361565 | FDPS | chr1 | 155282186 | + | IPO9 | chr1 | 201840289 | + |
| 5CDS-intron | ENST00000447866 | ENST00000464348 | FDPS | chr1 | 155282186 | + | IPO9 | chr1 | 201840289 | + |
| In-frame | ENST00000368356 | ENST00000361565 | FDPS | chr1 | 155282186 | + | IPO9 | chr1 | 201840289 | + |
| 5CDS-intron | ENST00000368356 | ENST00000464348 | FDPS | chr1 | 155282186 | + | IPO9 | chr1 | 201840289 | + |
| 3UTR-3CDS | ENST00000487002 | ENST00000361565 | FDPS | chr1 | 155282186 | + | IPO9 | chr1 | 201840289 | + |
| 3UTR-intron | ENST00000487002 | ENST00000464348 | FDPS | chr1 | 155282186 | + | IPO9 | chr1 | 201840289 | + |
| In-frame | ENST00000356657 | ENST00000361565 | FDPS | chr1 | 155282186 | + | IPO9 | chr1 | 201840289 | + |
| 5CDS-intron | ENST00000356657 | ENST00000464348 | FDPS | chr1 | 155282186 | + | IPO9 | chr1 | 201840289 | + |
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FusionProtFeatures for FDPS_IPO9 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| FDPS | IPO9 |
| Key enzyme in isoprenoid biosynthesis which catalyzesthe formation of farnesyl diphosphate (FPP), a precursor forseveral classes of essential metabolites including sterols,dolichols, carotenoids, and ubiquinones. FPP also serves assubstrate for protein farnesylation and geranylgeranylation.Catalyzes the sequential condensation of isopentenyl pyrophosphatewith the allylic pyrophosphates, dimethylallyl pyrophosphate, andthen with the resultant geranylpyrophosphate to the ultimateproduct farnesyl pyrophosphate. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | IPO9 | chr1:155282186 | chr1:201840289 | ENST00000361565 | + | 17 | 24 | 43_119 | 803 | 1042 | Domain | Importin N-terminal |
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FusionGeneSequence for FDPS_IPO9 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_FDPS_ENST00000447866_chr1_155282186_+_IPO9_ENST00000361565_chr1_201840289_+_333aa MNGDQNSDVYAQEKQDFVQHFSQIVRVLTEDEMGHPEIGDAIARLKEVLEYNAIGGKYNRGLTVVVAFRELVEPRKQDADSLQRAWTVGW CVELSLIMVFAHLVHTQLEPLLEFLCSLPGPTGKPALEFVMAEWTSRQHLFYGQYEGKVSSVALCKLLQHGINADDKRLQDIRVKGEEIY SMDEGIRTRSKSAKNPERWTNIPLLVKILKLIINELSNVMEANAARQATPAEWSQDDSNDMWEDQEEEEEEEEDGLAGQLLSDILATSKY >In-frame_FDPS_ENST00000368356_chr1_155282186_+_IPO9_ENST00000361565_chr1_201840289_+_399aa MPLSRWLRSVGVFLLPAPYWAPRERWLGSLRRPSLVHGYPVLAWHSARCWCQAWTEEPRALCSSLRMNGDQNSDVYAQEKQDFVQHFSQI VRVLTEDEMGHPEIGDAIARLKEVLEYNAIGGKYNRGLTVVVAFRELVEPRKQDADSLQRAWTVGWCVELSLIMVFAHLVHTQLEPLLEF LCSLPGPTGKPALEFVMAEWTSRQHLFYGQYEGKVSSVALCKLLQHGINADDKRLQDIRVKGEEIYSMDEGIRTRSKSAKNPERWTNIPL LVKILKLIINELSNVMEANAARQATPAEWSQDDSNDMWEDQEEEEEEEEDGLAGQLLSDILATSKYEEDYYEDDEEDDPDALKDPLYQID >In-frame_FDPS_ENST00000356657_chr1_155282186_+_IPO9_ENST00000361565_chr1_201840289_+_399aa MPLSRWLRSVGVFLLPAPYWAPRERWLGSLRRPSLVHGYPVLAWHSARCWCQAWTEEPRALCSSLRMNGDQNSDVYAQEKQDFVQHFSQI VRVLTEDEMGHPEIGDAIARLKEVLEYNAIGGKYNRGLTVVVAFRELVEPRKQDADSLQRAWTVGWCVELSLIMVFAHLVHTQLEPLLEF LCSLPGPTGKPALEFVMAEWTSRQHLFYGQYEGKVSSVALCKLLQHGINADDKRLQDIRVKGEEIYSMDEGIRTRSKSAKNPERWTNIPL LVKILKLIINELSNVMEANAARQATPAEWSQDDSNDMWEDQEEEEEEEEDGLAGQLLSDILATSKYEEDYYEDDEEDDPDALKDPLYQID |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_FDPS_ENST00000447866_chr1_155282186_+_IPO9_ENST00000361565_chr1_201840289_+_999nt ATGAACGGAGACCAGAATTCAGATGTTTATGCCCAAGAAAAGCAGGATTTCGTTCAGCACTTCTCCCAGATCGTTAGGGTGCTGACTGAG GATGAGATGGGGCACCCAGAGATAGGAGATGCTATTGCCCGGCTCAAGGAGGTCCTGGAGTACAATGCCATTGGAGGCAAGTATAACCGG GGTTTGACGGTGGTAGTAGCATTCCGGGAGCTGGTGGAGCCAAGGAAACAGGATGCTGATAGTCTCCAGCGGGCCTGGACTGTGGGCTGG TGTGTGGAACTGTCCCTGATCATGGTGTTCGCTCATCTGGTGCACACTCAGCTAGAACCTCTCTTGGAGTTCCTGTGTAGCCTCCCAGGA CCTACTGGCAAACCTGCTCTAGAGTTTGTGATGGCTGAGTGGACAAGCCGACAGCACCTGTTCTATGGACAGTATGAAGGCAAAGTCAGC TCTGTGGCACTCTGTAAGCTGCTCCAGCATGGCATCAATGCAGATGACAAACGGCTACAGGATATCCGTGTGAAGGGAGAGGAGATCTAC AGCATGGATGAGGGCATCCGCACCCGCTCTAAGTCAGCCAAAAACCCAGAACGCTGGACAAACATTCCTTTGCTGGTCAAGATCCTAAAG CTGATCATCAACGAGCTCTCCAACGTCATGGAGGCTAATGCCGCTCGCCAGGCCACTCCTGCAGAGTGGAGTCAAGATGACTCCAATGAT ATGTGGGAGGACCAGGAGGAGGAAGAGGAGGAGGAGGAGGATGGTTTAGCTGGCCAACTTTTATCTGACATTCTTGCTACAAGTAAATAT GAGGAGGATTACTACGAGGATGATGAGGAAGATGACCCTGATGCCCTGAAGGATCCTCTCTATCAGATTGATCTGCAGGCATATCTCACA GATTTCCTCTGCCAGTTTGCTCAGCAGCCCTGCTACATAATGTTTTCAGGCCACCTTAATGACAATGAGAGGCGAGTTCTACAGACCATC >In-frame_FDPS_ENST00000368356_chr1_155282186_+_IPO9_ENST00000361565_chr1_201840289_+_1197nt ATGCCCCTGTCCCGCTGGTTGAGATCTGTGGGGGTCTTCCTGCTGCCAGCCCCCTACTGGGCACCCCGGGAGAGGTGGCTGGGTTCCCTA CGGCGGCCCTCCCTGGTGCACGGGTACCCAGTCCTGGCCTGGCACAGTGCCCGCTGCTGGTGCCAAGCGTGGACAGAGGAACCTCGAGCC CTTTGCTCCTCCCTCAGAATGAACGGAGACCAGAATTCAGATGTTTATGCCCAAGAAAAGCAGGATTTCGTTCAGCACTTCTCCCAGATC GTTAGGGTGCTGACTGAGGATGAGATGGGGCACCCAGAGATAGGAGATGCTATTGCCCGGCTCAAGGAGGTCCTGGAGTACAATGCCATT GGAGGCAAGTATAACCGGGGTTTGACGGTGGTAGTAGCATTCCGGGAGCTGGTGGAGCCAAGGAAACAGGATGCTGATAGTCTCCAGCGG GCCTGGACTGTGGGCTGGTGTGTGGAACTGTCCCTGATCATGGTGTTCGCTCATCTGGTGCACACTCAGCTAGAACCTCTCTTGGAGTTC CTGTGTAGCCTCCCAGGACCTACTGGCAAACCTGCTCTAGAGTTTGTGATGGCTGAGTGGACAAGCCGACAGCACCTGTTCTATGGACAG TATGAAGGCAAAGTCAGCTCTGTGGCACTCTGTAAGCTGCTCCAGCATGGCATCAATGCAGATGACAAACGGCTACAGGATATCCGTGTG AAGGGAGAGGAGATCTACAGCATGGATGAGGGCATCCGCACCCGCTCTAAGTCAGCCAAAAACCCAGAACGCTGGACAAACATTCCTTTG CTGGTCAAGATCCTAAAGCTGATCATCAACGAGCTCTCCAACGTCATGGAGGCTAATGCCGCTCGCCAGGCCACTCCTGCAGAGTGGAGT CAAGATGACTCCAATGATATGTGGGAGGACCAGGAGGAGGAAGAGGAGGAGGAGGAGGATGGTTTAGCTGGCCAACTTTTATCTGACATT CTTGCTACAAGTAAATATGAGGAGGATTACTACGAGGATGATGAGGAAGATGACCCTGATGCCCTGAAGGATCCTCTCTATCAGATTGAT CTGCAGGCATATCTCACAGATTTCCTCTGCCAGTTTGCTCAGCAGCCCTGCTACATAATGTTTTCAGGCCACCTTAATGACAATGAGAGG >In-frame_FDPS_ENST00000356657_chr1_155282186_+_IPO9_ENST00000361565_chr1_201840289_+_1197nt ATGCCCCTGTCCCGCTGGTTGAGATCTGTGGGGGTCTTCCTGCTGCCAGCCCCCTACTGGGCACCCCGGGAGAGGTGGCTGGGTTCCCTA CGGCGGCCCTCCCTGGTGCACGGGTACCCAGTCCTGGCCTGGCACAGTGCCCGCTGCTGGTGCCAAGCGTGGACAGAGGAACCTCGAGCC CTTTGCTCCTCCCTCAGAATGAACGGAGACCAGAATTCAGATGTTTATGCCCAAGAAAAGCAGGATTTCGTTCAGCACTTCTCCCAGATC GTTAGGGTGCTGACTGAGGATGAGATGGGGCACCCAGAGATAGGAGATGCTATTGCCCGGCTCAAGGAGGTCCTGGAGTACAATGCCATT GGAGGCAAGTATAACCGGGGTTTGACGGTGGTAGTAGCATTCCGGGAGCTGGTGGAGCCAAGGAAACAGGATGCTGATAGTCTCCAGCGG GCCTGGACTGTGGGCTGGTGTGTGGAACTGTCCCTGATCATGGTGTTCGCTCATCTGGTGCACACTCAGCTAGAACCTCTCTTGGAGTTC CTGTGTAGCCTCCCAGGACCTACTGGCAAACCTGCTCTAGAGTTTGTGATGGCTGAGTGGACAAGCCGACAGCACCTGTTCTATGGACAG TATGAAGGCAAAGTCAGCTCTGTGGCACTCTGTAAGCTGCTCCAGCATGGCATCAATGCAGATGACAAACGGCTACAGGATATCCGTGTG AAGGGAGAGGAGATCTACAGCATGGATGAGGGCATCCGCACCCGCTCTAAGTCAGCCAAAAACCCAGAACGCTGGACAAACATTCCTTTG CTGGTCAAGATCCTAAAGCTGATCATCAACGAGCTCTCCAACGTCATGGAGGCTAATGCCGCTCGCCAGGCCACTCCTGCAGAGTGGAGT CAAGATGACTCCAATGATATGTGGGAGGACCAGGAGGAGGAAGAGGAGGAGGAGGAGGATGGTTTAGCTGGCCAACTTTTATCTGACATT CTTGCTACAAGTAAATATGAGGAGGATTACTACGAGGATGATGAGGAAGATGACCCTGATGCCCTGAAGGATCCTCTCTATCAGATTGAT CTGCAGGCATATCTCACAGATTTCCTCTGCCAGTTTGCTCAGCAGCCCTGCTACATAATGTTTTCAGGCCACCTTAATGACAATGAGAGG |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_FDPS_ENST00000447866_chr1_155282186_+_IPO9_ENST00000361565_chr1_201840289_+_9458nt TCAGCGCGGCTCATCTTCGCCCAGCCAGGACACGCAGGATCGCGTTATCTGTCCCTCCCGCGGGCACATTGGGAGTTGTAGTCTAATTAT ATATTTCCGCCCTTAGTGTGGGGAGAGCGGGAACTACTCGACCCACAGAGCCGATCGCGGAGCGGATTCTGCTTTTAGGAGTACCCGCCA ACAAGCGGGACCGAGCAGGAATCCGTATCTGGGAACAGAATGAACGGAGACCAGAATTCAGATGTTTATGCCCAAGAAAAGCAGGATTTC GTTCAGCACTTCTCCCAGATCGTTAGGGTGCTGACTGAGGATGAGATGGGGCACCCAGAGATAGGAGATGCTATTGCCCGGCTCAAGGAG GTCCTGGAGTACAATGCCATTGGAGGCAAGTATAACCGGGGTTTGACGGTGGTAGTAGCATTCCGGGAGCTGGTGGAGCCAAGGAAACAG GATGCTGATAGTCTCCAGCGGGCCTGGACTGTGGGCTGGTGTGTGGAACTGTCCCTGATCATGGTGTTCGCTCATCTGGTGCACACTCAG CTAGAACCTCTCTTGGAGTTCCTGTGTAGCCTCCCAGGACCTACTGGCAAACCTGCTCTAGAGTTTGTGATGGCTGAGTGGACAAGCCGA CAGCACCTGTTCTATGGACAGTATGAAGGCAAAGTCAGCTCTGTGGCACTCTGTAAGCTGCTCCAGCATGGCATCAATGCAGATGACAAA CGGCTACAGGATATCCGTGTGAAGGGAGAGGAGATCTACAGCATGGATGAGGGCATCCGCACCCGCTCTAAGTCAGCCAAAAACCCAGAA CGCTGGACAAACATTCCTTTGCTGGTCAAGATCCTAAAGCTGATCATCAACGAGCTCTCCAACGTCATGGAGGCTAATGCCGCTCGCCAG GCCACTCCTGCAGAGTGGAGTCAAGATGACTCCAATGATATGTGGGAGGACCAGGAGGAGGAAGAGGAGGAGGAGGAGGATGGTTTAGCT GGCCAACTTTTATCTGACATTCTTGCTACAAGTAAATATGAGGAGGATTACTACGAGGATGATGAGGAAGATGACCCTGATGCCCTGAAG GATCCTCTCTATCAGATTGATCTGCAGGCATATCTCACAGATTTCCTCTGCCAGTTTGCTCAGCAGCCCTGCTACATAATGTTTTCAGGC CACCTTAATGACAATGAGAGGCGAGTTCTACAGACCATCGGCATCTAAAAAGGGGAGCCTTTCTACATTTGCTCCTTCTGGGCCAGCCGC AAACCATTTTGCAGCCCTCACTGGCCTTGAGATGCACTTTCTTCTCAACCTAAAGTGGCATCTTGACCCTTGGCCCTTGGCCTCGGCAGT GACACTGATGACAATTCAGACCAGGCTCACCGGTGCCGTCACTTAGGAATGCTGGAACAAAGGACATTTCTCAAAGTTCCCCTGAAGACA TGCCATCTCTAGAACCTTTTTTCTCCCCGACTCTACCCCCACCTCTGTTCCTAGAGCCCTCTGCTGGCGAGTCCAGAAACATTATTGCCC AGAAGGATTATGTGTTTATGGATTATTTTGCCCCGCCTCAGGAGCGCAGGAAGTCACTACCATTTATATTCTAAAACAGACCTATCTATG TTCATAGGACTTCTGATGTGTTCAGATAGGAATCCTCATGAGAGATCATTATGCTTTGTGCCCTGGACCACTGCTGCTCTGGGTTCTCAG GAGGAACAGGCAAGAGCAGCTTCATTCTAAGCCTTTCCAGTGACCTCAGCCTTGCTTCTCTTCTACAACACTAAGGCTCCTCTGTCAGAG GAGGTCGTCTTGTTTTTGCTTCATTGCATGACATAACCCTTCCCCTCAAGCTGTTCCTATATATACATGCACACACAAAATAAGCCAGAC AGATGGCAATTTGATCTTCCTTTTTTAGAAAAAAAAAAAAAAATGGGGAAAAGGGATTTTTTTTAAATCCACCTGACCCAACTATATTTA ATATGCCTCTCCCACACATTACCACAGAGTCTGATATTCAAAGGTTATCCCCTTTCCCTCAGGAAGCCTCTAAAGTGCTTAAGTTGTAGC CCTCAAATTTGCAACATGTATTTTTCTAGGACAGTAAAGTAATCTTTACAAATGAATTTAGTTGCATGGTATAAGGTGTCTCAGCACCTG TTTGCCTTCTATTCCCTTTAGAAGGTAAGTAAAAGTAATGGGGGAAAGGATTAGGTGGAGCCTGTCTAAACATTCTAGTGTGTCTTGGCA AACATAGCCTGAAATGATTCTTAAAGAACTGGCATTGTTTAATCAAATATTTTTAAGGGAGATTCCTTAATTGGGAAGTTTAGTCTGTTT GGGGTTCAAAGAGTAAATGAGGATTAGAAAATCATGGAGAGAGGCTGGGCGCGGTGGCTAACGCCTGTAATCCTAGCACTTTGGGAGGCT GAGATGGGCGGATCACTTGAGATCAGGAGTTTGAGGCTAGCCTGGCCAACACAGTGAAACCTGCATTTCTACTAAAAATACAAAAATTAG CTGGGCATGGTGGTGCATGCCTGTAATCCCAGTTAACTTGAGATGCTGAGGCAGGAGAATCGCTTGAACTTGGGAAGCAGAGGTTGCAGT GAACCGATATCACACCGTTGCATTCCAAGGCAAGACTCAATCACACACACACACACACACACACACAAATCATGGGGAGAAAGATGAAAC CTGTGTTCCCCTTTTTTTGGTAGTGCCCACATCTGGTGCCCCATTTTTAATAACCACAGGATATTTCTTTAGATTGATATTCTCACAAAG AAGAAATAGAATATAGGCTGGGCGTGGTGTGTCACACCTGTAATCCCAGCACTTACGGAGGCCGAAGCCAGCGGATCACCAGAGGTCAGG AGTTCGAGACCAGCCTGACCAACATGATGAAACCCTGTCTCTACTAAAAATACAAAAATTAGCCAGGCATGGTGGCATGCACTTGTAATC CCAGCTACTCGGGAGGCTGAGACAGGAGAATCGCTTGAACCTGGGAGGCAGAGGTTGCAGTAAGCCAAGATCGCACCATTGCACTACAGC CTGGGCAACAAGAGGAGCGAAACTCTGTCTCAAAAAAAAAAAAGAGAAAGAATATAAAGTGAATCTGAATCTCCACTCAAGGGGATGGCC CCAAGGATATTGTAGCTGGTAATTTCTTCATGCCACTAGGTGTCCCCAGTGTTCAACCTCCATGACTGAGATTGGAAGAAGTAGAGTTAA AAGTTTTTACTACCTTTGAGAAGCCTGCGGGCATGTTCACAGTCGTCCCATGCCAGCCAGGTTCTGAGGCTAACTGCTTGTGCCCCTGCT GCTTCACATGGCATTGTGGGAGTTGCTGATACTGGGGAAATGATGGCAGATCTGACCAAGTGGTGCTGAGAAAACCACCCTCGGCCTTGC AGACTCCATAGTTTATCTCAAGGCAGTGCCAGTCGGATTTGGTGCTAAAGGCATAAGGCCAAGTCAGCCTCTGATATTGGCACAAAAGAA TGGTCTCATGCCAGTAGCATTGAACTGCTGAGCTTGGGAAGGCTTAAGGCTCCCACACACAGACTGAGAATGATGGGGGTCCCTCTGCGT CTGCTAATTAGACAAACATTCTATATCTAGTGCCAAAAGTGGTCCTAAATCCTTTGGCAAGGGTCCTTTCTGCTCTCATGCTGATTTGGG GGAGGACTGGGCATCCTGCCTCAGGAGAACTTGAGTCCTGAGGAAAGGGCCCTAGTAACACTTAAGGGCTACCCCTGGCTAACAGATACT CGGCTGTGGGTGAGAGCAGAAGGTCTTGGACCCCTCGATGTGCAGGTACTTAATTGTGTTTCCAGTGCATTTTCATATACATTATCCCAT TTAACCTTTATAACAGGTTCACAGAGTGGATATTCCCATTCTGTTGATGAGAAAAAGAGTGGAGAGACTGTGTCCAGTGTCAGCAGGAAG AAAAAAGATCTGTTGGAGGCCAGTACATGTTGACAGAAACTCTAGACCATATTTTGTCTCCTGTCTTTGGCCAAAGAGAACTAGCTTCAG TCTGAAAAGGGCAGGGCTAAGTGGTTACAAGGAACTAAAAAGTTCAAGGTAAGACAAATGAGGTAAAAATAAAAAAGAGCACTTAGCTGC TCTGAGACATTTTAGTCTCCTGACTGGTAAACAGCAGCTGGGGCACCAAGGGGCTCCCAGGAGTTTGTCGAGCTTTTATTGGAGTGAACT GAAAGGAAAATGGAAGGAATGCTATAAGACTGAAAAGAAGTTAAAGCCCTAGGAAGGAAGCTGATAACACAAGTTACAGACGTATATGTG ACATTGATTTGGGAGAATGAACCTACAACAAATGACCCAAAAGCACCTAAATAAGAGTGACGAGAGTTTAACAGACATTCATTATGGACT TCAGAGAAAATGATGCTAAACTGGTCTTAGAATCTTCTTTAATTTTGTTAACTAGGTAAATAATCTGGACATTTTAGTCAAAGCATTAGA CAGACAGAGAAGTTGGTAACTGACCACTAACTAACAAACTATAAATTCACCCATTGTGGGTTGACCTGGTAAGTTCCCCCAGGGCTGTGT CCTTGGCCCCTCCTTTGATATTAGTGACAGATGACTTTTTTTATGCCTTACCCATTCCACAAAAGAATTTGAAGCCATTTACACAAGAGA TAGTACTAGTAAATTAGGAGTGCTGATCAAATTTTTAGATAATAAGAAACCCTTAGGAAGGATGACAATTTAGAATCCAAATTTAGGATC CAAACAAATACCATTACAAACTATAAAAATGAGCAGAATCTAAATGTAACATTTCAATAAATGCAGATTGATAATAACATCTGTGCAGAG TTGAGGACTATAGAGTACTGTGCTGTCACTAACAGTATTGTGTGCTACTAAGAGTTTAATGGCTGGGTGTGGTGGCTCACACCTGTAATC CCAACACTTTGGGAGGCCTAGGTGGGTAAATCAGCTGAGATCAGGAGTTCGAGACCAGCCTGGCCAATGTGGTGAAACCCCGCCTCTACT AAAAATAAAAAAATTAGCTGGGCATGGTGGCACGTGCCTGTAATCCCAGCTACTCGGGAGGCTGAGGCGGGAGAATCACTTGAACCTGGG AGACAGAGGTTGCAGTGAGTCGAGATCACACCATTGCACTCCAGCCTGGGCAACAGAGCAAGATTCTGTCTCAAAAAATAAAGTTTATTA TGCCAGGAGGGCCAGGTGTGGTGCCACACCCATGTAATCCCAGCACTTTAGGAGGCTGAGGAGGGCAGATCACTTAAGCCCAAGAGTTTG AGACCAGTCTGGGCAATGTGGCAATACCTTGTCTCTTAAAATTTAAAATAAAAAAAAAGTTTATTATGCCAGGAACTGTTAATGTGTCCA AAAAAACTCCAGTGTGGTTCTAGGATGAGATAATAAAAACAGGTTGTCTAGGGTAGTGTGGAAGGTCCTTTCAGTCTTCCTGTGCCTATC AGTGATCCTCATTGCCATGTTCCCTTCTGGTGCTCAACCGGAGGCTCCCTGACAGATGAGTCCTCTGCCAGAGGAAGGCTAAGATGTAGA GGACAAATCGTGTCAAGGAAAAGAAGCTTGAAGGAGCTAAGAATGCTTAGCTTAGAGAAGACAAGAGGAAACAGGACATGGCTTTGGGAA GTTCAAGGATGGTCCAGTGAAATACATACTATACTTTTGCACCCCAGCTAAGCTGACCCATGATCAGTAAGTAGGAAATAAAAGGCCAAT TTCTGGCTACTCTTGCCCCCAACCCCATTTCAGTGAACTATGAACCTCTATTAGATATGCAAGGCCGGTGCTAAATGCTGGAGGGCTTTG GCCCTTTCCCTCAAGGAGCTAGTCTAGTAGGGGGTCAGAAATACAGATGGGCCTGAACATAATGATGGTTTGACTTCCAGTTTTTCAACT TTAGGATTGTGCAAAAGCTATACACATTCGGTAGAAACAGTACTTCAAGTATCCATACAATCAGTACAGTATTCAATAAATTACATGAGA CATTCAACACTTTATTATAAAATAGGCTTTGTGTTAGATGAGTTTGCCCAACTGTAAGCTAATGTAAGTGATCTGAGTAGGTTTAAGGTA GCCTAGGTGTATTAAATGCATTTTTCACTTAACGGTATTTTCAACTTTTGTTGGGTTTATTGGGATGTAGCCCCATTATAAGCTGAAAAG CATCTGTAGTATAATAAATGTGGGGAGTGCTGTGAGAGAAATAAGTGTACTGGGTTTAGTTCCCACTGCCCAAAAAAGGAACTGGCTAAT GGTAACCTGGGGGAGGAAGTCGGGTAAGTTGCATGGAGAAGGCAACCCTTGAACACTTGCAAGGAGCTAACAATACCTGCTTCTGGAGTA TTTAAACGCCAGTGGGTATGCTAAATACTTTTACCTCAGACCACCTACTAACCTTACAAAGTAGTCCACTTTGCTCACCCAGTTTTACAG ATTGATGAAACTGAAGCAGACAGATATTGTTAACCTATCAAAGGTCACCCTGCAAGTGTGTGATTATAGTCCAAGCAGCTTGTACTTGTT GCCTATTTGTTTTGCCTTTCCTGTGCATTTGCCAGGCAGATGAGAGTGGGGTAAGACATTGCAGAGAAAAAGTAAGAAAAGGCCGTCATG AAACAATTTCATTTTCAGACCTTATAAGCACGTTACAAGTACTGATATTTATGCTTAAGTTCACGGGAGTCCTGGCCAGAAATAAAGCTG GAAGGACAAGTGGGGGGCAGATTGTGAAGGATCCTTCAAGACCTGCTTCCTCTAGAGAATGGGAGACTACCCAAGATAACTAAACAGGGA AGTGATCAGGTTTTGTGTCTTAGAAAAGTGTTGCAGTGTTGATGCAAATGTGACTAGAAGGGTGACTTGGAACCTGGATTGAAGGGGTGG GAGATGGGAGAAAGGAATGCAGTCTGGCAGCAGCTACAGCAGTCCAGGTGGGAAAACCCAGAGCCTGAACTAAGGTTGTAACTAGAGGGG ATAGGGTGGAAGAGCTGGATTAGAGATGTTGACAAGATAAAGTCAGTAGGACTTAAAGACTGACAAGTAAGGATTTTCCAAAAGTGAGAG CTGTGGAATGAATTGTCTTAAAATGTTGCAGTGAGTTCCTCCTCATCAATCCAAGTGCTCGATCAGAGGCTAGACCTTTAGTTAGCAGTC ACGGGAAAATTCCCCATTCTCACGGGGATTTAGACTAGGTCTTAACCATACTTTACCAAGATTCCAGTAGCAAAGCACCCAAAAGTAATC GCAATAAAATTCCAATTTTTGTAGGCCGGGCATAGTGGCTCACACCTGTAATCCCAGCACTTTGGGAGGCCGAGGCAGGCGGACCACGAC ATCAAGAGTTCAAGAGCAGCCTGGCCAGCATGGTGAAACCCCGTCTCTACTAAAAATACAAAAAAATTAGCTGGGCATGGTGGCGCATGC CTATAATCCTAGCTACTCAGGCAGCTGAAGCAGGAGAATTGCTTGAACCCGGGAGGCAGAGGTTGCAGTGAGCCAAGATCATGCCACTAC ACTCCAGCCTGGGCGACAGAGCGACACTCTGCCTCAAAAAAAAAAAAAAACAAAAAAAAAAACAAGTTTTGTGAATTTAAGTTTCCCTAA TGGATGGTACAGGTCAACATTTGCCATCTAATGACACTTACATTCCAGTTTTTTCCTTTTTTGAGTAACTGGGAAAAGGGTGGCATTACT GCTGGCTTCCTAAAATTGAAAAGTATACTAGGGTTTTTAAACCTGTGTAGAATACATGATATGGTAGCAAATGTGCTGTAGGAAGAAAAG CAATGAGGAACTACTGGCCTGACTAGGAGGCCTAGAAGTCCCTCCCAGGCTTGAGTTGTTCTGACTTGGCATGATTACATAGCTGCGGCA AGTGACGTTTCCTTCAAGCCTTGGTTCCCTCATCTGTAAAATAGGGAACTAATACCTACCTCACAGGATTGTAGTTAGAATTAAGGATGA CTTCATTAAAGCACCTCTAGTGGTGGAAGATGTCCCATCCTATCCCCCACCCATAGCTGGGAGCTATGTTTGGCTCATTCTTCCTGACTC ACTGGATTACACTGTGACTCAGTTCAATTTCACACATGCTGCTGCTAAATTAGGGTCTTGGTGAGCCTTTGGGAGGACAGCTCTGAGGAA TGAATTGTAGCACTGCAGCCCTGCCTGAGGAACATGATAGAAACAGGTGGTAGGCCCAGCTCTTGCCTTCCACCTACTAAGCAGTTTTTC TGTGGTTAGCTGTGTGACATAAACTATCGGTGTATTAATTTGCTTTCACTAGATTCCCCCCCCCCCAACAACTTAGTCCAAGAACATACC TGAATTCTTTGCATTTCCTTGCCTTAGTTGCTTTTGTAGGGTGGACAGCAGGACTGCATGAGAATAGCTGTGCTTCTGGACCCTATGGTG AAAGCTCTAGTGAACTGCAATTAGGCCCAGGGTCCCGGAGGAAGAAGGGGAGAGAAAAAGGGGGGTAGTTTTCCAAAAGATAAGTAGGGG ACAAAAAAGTCCACGGGGCCTATGAGCGGTGAGACTCCTGCCCTGATTGTGGCAAAGCACCTGGAGATGATAGAACTTCCTAGGGAAAAG GCTGCATGGAGTCCCCAGGGATGCTGGGCCCTGGTCACCAAGGCTCCCTGGGAAGGTCTCTTGTACCTGGGGCACACAGACCAACACTTC TGAATTTGCAAGCTTAAGAGCATGTATGAGCAGAACCTGTGCAGACCAAGGCTTAGAGGGCTCACCTCAATGTTTTGCACTGTGTGAGAC CCCAGGACCTTTTCGTGATTCTGGAGAGGGGAACAAACCATAATAACAACAAACCAGGTAGCAGGATAGAGACTCATTCTCATCTATTTT GGTTAAAAGAAAATAAATGTATTTCTTCCACACCTGATTTTGTGATTGCAAATTCATAACTAATATCCCTCGTCAGCTCCGCTGACTCAT CCCTGCCACAGGGAGGTTCACAGCAAGAGCACAGAAACTAGGGCCAGTGCCCGGTTGTGTGACCTTGAGTAAGTTCTTTTTCCCTTGAAC AGGGAGAGAGACACAATGGATCAGAGTGTCTCTGCCAGTTCTAACTTGGGGATTCTAGTGGGTTGAACCGAACGGTAGTCCGTTTCCAAA AGAGGAAGCCAAGACCAGAGGGGGAGTGGTTCCTTCAAGTTTGCAGAACCAGTAAGTGGCAGAGCAGGACTCATATCTAGTTAGTGGTTC AGAGCATGGGCTCCGGAGCTAGACTGCCTGGATTTGAACCCTGGCTTTGCCACTTGCCTGTTGGGTGACTTTGGACAAGCTGCTTAAATT ATGTCTCCATTTCCTAATCCACAGAACAAGTGTAATACTAGTTATCTGTTTCATGGAGTGATTGTGAGGATTAAATAAAGTTAATATAAC >In-frame_FDPS_ENST00000368356_chr1_155282186_+_IPO9_ENST00000361565_chr1_201840289_+_9552nt AGTGTGGGGAGAGCGGGAACTACTCGACCCACAGAGCCGATCGCGGAGCGGATTCTGCTTTTAGGAGTACCCGCCAACAAGCGGGACCGA GCAGGAATCCGTATCTGGGAACAGGATGCCCCTGTCCCGCTGGTTGAGATCTGTGGGGGTCTTCCTGCTGCCAGCCCCCTACTGGGCACC CCGGGAGAGGTGGCTGGGTTCCCTACGGCGGCCCTCCCTGGTGCACGGGTACCCAGTCCTGGCCTGGCACAGTGCCCGCTGCTGGTGCCA AGCGTGGACAGAGGAACCTCGAGCCCTTTGCTCCTCCCTCAGAATGAACGGAGACCAGAATTCAGATGTTTATGCCCAAGAAAAGCAGGA TTTCGTTCAGCACTTCTCCCAGATCGTTAGGGTGCTGACTGAGGATGAGATGGGGCACCCAGAGATAGGAGATGCTATTGCCCGGCTCAA GGAGGTCCTGGAGTACAATGCCATTGGAGGCAAGTATAACCGGGGTTTGACGGTGGTAGTAGCATTCCGGGAGCTGGTGGAGCCAAGGAA ACAGGATGCTGATAGTCTCCAGCGGGCCTGGACTGTGGGCTGGTGTGTGGAACTGTCCCTGATCATGGTGTTCGCTCATCTGGTGCACAC TCAGCTAGAACCTCTCTTGGAGTTCCTGTGTAGCCTCCCAGGACCTACTGGCAAACCTGCTCTAGAGTTTGTGATGGCTGAGTGGACAAG CCGACAGCACCTGTTCTATGGACAGTATGAAGGCAAAGTCAGCTCTGTGGCACTCTGTAAGCTGCTCCAGCATGGCATCAATGCAGATGA CAAACGGCTACAGGATATCCGTGTGAAGGGAGAGGAGATCTACAGCATGGATGAGGGCATCCGCACCCGCTCTAAGTCAGCCAAAAACCC AGAACGCTGGACAAACATTCCTTTGCTGGTCAAGATCCTAAAGCTGATCATCAACGAGCTCTCCAACGTCATGGAGGCTAATGCCGCTCG CCAGGCCACTCCTGCAGAGTGGAGTCAAGATGACTCCAATGATATGTGGGAGGACCAGGAGGAGGAAGAGGAGGAGGAGGAGGATGGTTT AGCTGGCCAACTTTTATCTGACATTCTTGCTACAAGTAAATATGAGGAGGATTACTACGAGGATGATGAGGAAGATGACCCTGATGCCCT GAAGGATCCTCTCTATCAGATTGATCTGCAGGCATATCTCACAGATTTCCTCTGCCAGTTTGCTCAGCAGCCCTGCTACATAATGTTTTC AGGCCACCTTAATGACAATGAGAGGCGAGTTCTACAGACCATCGGCATCTAAAAAGGGGAGCCTTTCTACATTTGCTCCTTCTGGGCCAG CCGCAAACCATTTTGCAGCCCTCACTGGCCTTGAGATGCACTTTCTTCTCAACCTAAAGTGGCATCTTGACCCTTGGCCCTTGGCCTCGG CAGTGACACTGATGACAATTCAGACCAGGCTCACCGGTGCCGTCACTTAGGAATGCTGGAACAAAGGACATTTCTCAAAGTTCCCCTGAA GACATGCCATCTCTAGAACCTTTTTTCTCCCCGACTCTACCCCCACCTCTGTTCCTAGAGCCCTCTGCTGGCGAGTCCAGAAACATTATT GCCCAGAAGGATTATGTGTTTATGGATTATTTTGCCCCGCCTCAGGAGCGCAGGAAGTCACTACCATTTATATTCTAAAACAGACCTATC TATGTTCATAGGACTTCTGATGTGTTCAGATAGGAATCCTCATGAGAGATCATTATGCTTTGTGCCCTGGACCACTGCTGCTCTGGGTTC TCAGGAGGAACAGGCAAGAGCAGCTTCATTCTAAGCCTTTCCAGTGACCTCAGCCTTGCTTCTCTTCTACAACACTAAGGCTCCTCTGTC AGAGGAGGTCGTCTTGTTTTTGCTTCATTGCATGACATAACCCTTCCCCTCAAGCTGTTCCTATATATACATGCACACACAAAATAAGCC AGACAGATGGCAATTTGATCTTCCTTTTTTAGAAAAAAAAAAAAAAATGGGGAAAAGGGATTTTTTTTAAATCCACCTGACCCAACTATA TTTAATATGCCTCTCCCACACATTACCACAGAGTCTGATATTCAAAGGTTATCCCCTTTCCCTCAGGAAGCCTCTAAAGTGCTTAAGTTG TAGCCCTCAAATTTGCAACATGTATTTTTCTAGGACAGTAAAGTAATCTTTACAAATGAATTTAGTTGCATGGTATAAGGTGTCTCAGCA CCTGTTTGCCTTCTATTCCCTTTAGAAGGTAAGTAAAAGTAATGGGGGAAAGGATTAGGTGGAGCCTGTCTAAACATTCTAGTGTGTCTT GGCAAACATAGCCTGAAATGATTCTTAAAGAACTGGCATTGTTTAATCAAATATTTTTAAGGGAGATTCCTTAATTGGGAAGTTTAGTCT GTTTGGGGTTCAAAGAGTAAATGAGGATTAGAAAATCATGGAGAGAGGCTGGGCGCGGTGGCTAACGCCTGTAATCCTAGCACTTTGGGA GGCTGAGATGGGCGGATCACTTGAGATCAGGAGTTTGAGGCTAGCCTGGCCAACACAGTGAAACCTGCATTTCTACTAAAAATACAAAAA TTAGCTGGGCATGGTGGTGCATGCCTGTAATCCCAGTTAACTTGAGATGCTGAGGCAGGAGAATCGCTTGAACTTGGGAAGCAGAGGTTG CAGTGAACCGATATCACACCGTTGCATTCCAAGGCAAGACTCAATCACACACACACACACACACACACACAAATCATGGGGAGAAAGATG AAACCTGTGTTCCCCTTTTTTTGGTAGTGCCCACATCTGGTGCCCCATTTTTAATAACCACAGGATATTTCTTTAGATTGATATTCTCAC AAAGAAGAAATAGAATATAGGCTGGGCGTGGTGTGTCACACCTGTAATCCCAGCACTTACGGAGGCCGAAGCCAGCGGATCACCAGAGGT CAGGAGTTCGAGACCAGCCTGACCAACATGATGAAACCCTGTCTCTACTAAAAATACAAAAATTAGCCAGGCATGGTGGCATGCACTTGT AATCCCAGCTACTCGGGAGGCTGAGACAGGAGAATCGCTTGAACCTGGGAGGCAGAGGTTGCAGTAAGCCAAGATCGCACCATTGCACTA CAGCCTGGGCAACAAGAGGAGCGAAACTCTGTCTCAAAAAAAAAAAAGAGAAAGAATATAAAGTGAATCTGAATCTCCACTCAAGGGGAT GGCCCCAAGGATATTGTAGCTGGTAATTTCTTCATGCCACTAGGTGTCCCCAGTGTTCAACCTCCATGACTGAGATTGGAAGAAGTAGAG TTAAAAGTTTTTACTACCTTTGAGAAGCCTGCGGGCATGTTCACAGTCGTCCCATGCCAGCCAGGTTCTGAGGCTAACTGCTTGTGCCCC TGCTGCTTCACATGGCATTGTGGGAGTTGCTGATACTGGGGAAATGATGGCAGATCTGACCAAGTGGTGCTGAGAAAACCACCCTCGGCC TTGCAGACTCCATAGTTTATCTCAAGGCAGTGCCAGTCGGATTTGGTGCTAAAGGCATAAGGCCAAGTCAGCCTCTGATATTGGCACAAA AGAATGGTCTCATGCCAGTAGCATTGAACTGCTGAGCTTGGGAAGGCTTAAGGCTCCCACACACAGACTGAGAATGATGGGGGTCCCTCT GCGTCTGCTAATTAGACAAACATTCTATATCTAGTGCCAAAAGTGGTCCTAAATCCTTTGGCAAGGGTCCTTTCTGCTCTCATGCTGATT TGGGGGAGGACTGGGCATCCTGCCTCAGGAGAACTTGAGTCCTGAGGAAAGGGCCCTAGTAACACTTAAGGGCTACCCCTGGCTAACAGA TACTCGGCTGTGGGTGAGAGCAGAAGGTCTTGGACCCCTCGATGTGCAGGTACTTAATTGTGTTTCCAGTGCATTTTCATATACATTATC CCATTTAACCTTTATAACAGGTTCACAGAGTGGATATTCCCATTCTGTTGATGAGAAAAAGAGTGGAGAGACTGTGTCCAGTGTCAGCAG GAAGAAAAAAGATCTGTTGGAGGCCAGTACATGTTGACAGAAACTCTAGACCATATTTTGTCTCCTGTCTTTGGCCAAAGAGAACTAGCT TCAGTCTGAAAAGGGCAGGGCTAAGTGGTTACAAGGAACTAAAAAGTTCAAGGTAAGACAAATGAGGTAAAAATAAAAAAGAGCACTTAG CTGCTCTGAGACATTTTAGTCTCCTGACTGGTAAACAGCAGCTGGGGCACCAAGGGGCTCCCAGGAGTTTGTCGAGCTTTTATTGGAGTG AACTGAAAGGAAAATGGAAGGAATGCTATAAGACTGAAAAGAAGTTAAAGCCCTAGGAAGGAAGCTGATAACACAAGTTACAGACGTATA TGTGACATTGATTTGGGAGAATGAACCTACAACAAATGACCCAAAAGCACCTAAATAAGAGTGACGAGAGTTTAACAGACATTCATTATG GACTTCAGAGAAAATGATGCTAAACTGGTCTTAGAATCTTCTTTAATTTTGTTAACTAGGTAAATAATCTGGACATTTTAGTCAAAGCAT TAGACAGACAGAGAAGTTGGTAACTGACCACTAACTAACAAACTATAAATTCACCCATTGTGGGTTGACCTGGTAAGTTCCCCCAGGGCT GTGTCCTTGGCCCCTCCTTTGATATTAGTGACAGATGACTTTTTTTATGCCTTACCCATTCCACAAAAGAATTTGAAGCCATTTACACAA GAGATAGTACTAGTAAATTAGGAGTGCTGATCAAATTTTTAGATAATAAGAAACCCTTAGGAAGGATGACAATTTAGAATCCAAATTTAG GATCCAAACAAATACCATTACAAACTATAAAAATGAGCAGAATCTAAATGTAACATTTCAATAAATGCAGATTGATAATAACATCTGTGC AGAGTTGAGGACTATAGAGTACTGTGCTGTCACTAACAGTATTGTGTGCTACTAAGAGTTTAATGGCTGGGTGTGGTGGCTCACACCTGT AATCCCAACACTTTGGGAGGCCTAGGTGGGTAAATCAGCTGAGATCAGGAGTTCGAGACCAGCCTGGCCAATGTGGTGAAACCCCGCCTC TACTAAAAATAAAAAAATTAGCTGGGCATGGTGGCACGTGCCTGTAATCCCAGCTACTCGGGAGGCTGAGGCGGGAGAATCACTTGAACC TGGGAGACAGAGGTTGCAGTGAGTCGAGATCACACCATTGCACTCCAGCCTGGGCAACAGAGCAAGATTCTGTCTCAAAAAATAAAGTTT ATTATGCCAGGAGGGCCAGGTGTGGTGCCACACCCATGTAATCCCAGCACTTTAGGAGGCTGAGGAGGGCAGATCACTTAAGCCCAAGAG TTTGAGACCAGTCTGGGCAATGTGGCAATACCTTGTCTCTTAAAATTTAAAATAAAAAAAAAGTTTATTATGCCAGGAACTGTTAATGTG TCCAAAAAAACTCCAGTGTGGTTCTAGGATGAGATAATAAAAACAGGTTGTCTAGGGTAGTGTGGAAGGTCCTTTCAGTCTTCCTGTGCC TATCAGTGATCCTCATTGCCATGTTCCCTTCTGGTGCTCAACCGGAGGCTCCCTGACAGATGAGTCCTCTGCCAGAGGAAGGCTAAGATG TAGAGGACAAATCGTGTCAAGGAAAAGAAGCTTGAAGGAGCTAAGAATGCTTAGCTTAGAGAAGACAAGAGGAAACAGGACATGGCTTTG GGAAGTTCAAGGATGGTCCAGTGAAATACATACTATACTTTTGCACCCCAGCTAAGCTGACCCATGATCAGTAAGTAGGAAATAAAAGGC CAATTTCTGGCTACTCTTGCCCCCAACCCCATTTCAGTGAACTATGAACCTCTATTAGATATGCAAGGCCGGTGCTAAATGCTGGAGGGC TTTGGCCCTTTCCCTCAAGGAGCTAGTCTAGTAGGGGGTCAGAAATACAGATGGGCCTGAACATAATGATGGTTTGACTTCCAGTTTTTC AACTTTAGGATTGTGCAAAAGCTATACACATTCGGTAGAAACAGTACTTCAAGTATCCATACAATCAGTACAGTATTCAATAAATTACAT GAGACATTCAACACTTTATTATAAAATAGGCTTTGTGTTAGATGAGTTTGCCCAACTGTAAGCTAATGTAAGTGATCTGAGTAGGTTTAA GGTAGCCTAGGTGTATTAAATGCATTTTTCACTTAACGGTATTTTCAACTTTTGTTGGGTTTATTGGGATGTAGCCCCATTATAAGCTGA AAAGCATCTGTAGTATAATAAATGTGGGGAGTGCTGTGAGAGAAATAAGTGTACTGGGTTTAGTTCCCACTGCCCAAAAAAGGAACTGGC TAATGGTAACCTGGGGGAGGAAGTCGGGTAAGTTGCATGGAGAAGGCAACCCTTGAACACTTGCAAGGAGCTAACAATACCTGCTTCTGG AGTATTTAAACGCCAGTGGGTATGCTAAATACTTTTACCTCAGACCACCTACTAACCTTACAAAGTAGTCCACTTTGCTCACCCAGTTTT ACAGATTGATGAAACTGAAGCAGACAGATATTGTTAACCTATCAAAGGTCACCCTGCAAGTGTGTGATTATAGTCCAAGCAGCTTGTACT TGTTGCCTATTTGTTTTGCCTTTCCTGTGCATTTGCCAGGCAGATGAGAGTGGGGTAAGACATTGCAGAGAAAAAGTAAGAAAAGGCCGT CATGAAACAATTTCATTTTCAGACCTTATAAGCACGTTACAAGTACTGATATTTATGCTTAAGTTCACGGGAGTCCTGGCCAGAAATAAA GCTGGAAGGACAAGTGGGGGGCAGATTGTGAAGGATCCTTCAAGACCTGCTTCCTCTAGAGAATGGGAGACTACCCAAGATAACTAAACA GGGAAGTGATCAGGTTTTGTGTCTTAGAAAAGTGTTGCAGTGTTGATGCAAATGTGACTAGAAGGGTGACTTGGAACCTGGATTGAAGGG GTGGGAGATGGGAGAAAGGAATGCAGTCTGGCAGCAGCTACAGCAGTCCAGGTGGGAAAACCCAGAGCCTGAACTAAGGTTGTAACTAGA GGGGATAGGGTGGAAGAGCTGGATTAGAGATGTTGACAAGATAAAGTCAGTAGGACTTAAAGACTGACAAGTAAGGATTTTCCAAAAGTG AGAGCTGTGGAATGAATTGTCTTAAAATGTTGCAGTGAGTTCCTCCTCATCAATCCAAGTGCTCGATCAGAGGCTAGACCTTTAGTTAGC AGTCACGGGAAAATTCCCCATTCTCACGGGGATTTAGACTAGGTCTTAACCATACTTTACCAAGATTCCAGTAGCAAAGCACCCAAAAGT AATCGCAATAAAATTCCAATTTTTGTAGGCCGGGCATAGTGGCTCACACCTGTAATCCCAGCACTTTGGGAGGCCGAGGCAGGCGGACCA CGACATCAAGAGTTCAAGAGCAGCCTGGCCAGCATGGTGAAACCCCGTCTCTACTAAAAATACAAAAAAATTAGCTGGGCATGGTGGCGC ATGCCTATAATCCTAGCTACTCAGGCAGCTGAAGCAGGAGAATTGCTTGAACCCGGGAGGCAGAGGTTGCAGTGAGCCAAGATCATGCCA CTACACTCCAGCCTGGGCGACAGAGCGACACTCTGCCTCAAAAAAAAAAAAAAACAAAAAAAAAAACAAGTTTTGTGAATTTAAGTTTCC CTAATGGATGGTACAGGTCAACATTTGCCATCTAATGACACTTACATTCCAGTTTTTTCCTTTTTTGAGTAACTGGGAAAAGGGTGGCAT TACTGCTGGCTTCCTAAAATTGAAAAGTATACTAGGGTTTTTAAACCTGTGTAGAATACATGATATGGTAGCAAATGTGCTGTAGGAAGA AAAGCAATGAGGAACTACTGGCCTGACTAGGAGGCCTAGAAGTCCCTCCCAGGCTTGAGTTGTTCTGACTTGGCATGATTACATAGCTGC GGCAAGTGACGTTTCCTTCAAGCCTTGGTTCCCTCATCTGTAAAATAGGGAACTAATACCTACCTCACAGGATTGTAGTTAGAATTAAGG ATGACTTCATTAAAGCACCTCTAGTGGTGGAAGATGTCCCATCCTATCCCCCACCCATAGCTGGGAGCTATGTTTGGCTCATTCTTCCTG ACTCACTGGATTACACTGTGACTCAGTTCAATTTCACACATGCTGCTGCTAAATTAGGGTCTTGGTGAGCCTTTGGGAGGACAGCTCTGA GGAATGAATTGTAGCACTGCAGCCCTGCCTGAGGAACATGATAGAAACAGGTGGTAGGCCCAGCTCTTGCCTTCCACCTACTAAGCAGTT TTTCTGTGGTTAGCTGTGTGACATAAACTATCGGTGTATTAATTTGCTTTCACTAGATTCCCCCCCCCCCAACAACTTAGTCCAAGAACA TACCTGAATTCTTTGCATTTCCTTGCCTTAGTTGCTTTTGTAGGGTGGACAGCAGGACTGCATGAGAATAGCTGTGCTTCTGGACCCTAT GGTGAAAGCTCTAGTGAACTGCAATTAGGCCCAGGGTCCCGGAGGAAGAAGGGGAGAGAAAAAGGGGGGTAGTTTTCCAAAAGATAAGTA GGGGACAAAAAAGTCCACGGGGCCTATGAGCGGTGAGACTCCTGCCCTGATTGTGGCAAAGCACCTGGAGATGATAGAACTTCCTAGGGA AAAGGCTGCATGGAGTCCCCAGGGATGCTGGGCCCTGGTCACCAAGGCTCCCTGGGAAGGTCTCTTGTACCTGGGGCACACAGACCAACA CTTCTGAATTTGCAAGCTTAAGAGCATGTATGAGCAGAACCTGTGCAGACCAAGGCTTAGAGGGCTCACCTCAATGTTTTGCACTGTGTG AGACCCCAGGACCTTTTCGTGATTCTGGAGAGGGGAACAAACCATAATAACAACAAACCAGGTAGCAGGATAGAGACTCATTCTCATCTA TTTTGGTTAAAAGAAAATAAATGTATTTCTTCCACACCTGATTTTGTGATTGCAAATTCATAACTAATATCCCTCGTCAGCTCCGCTGAC TCATCCCTGCCACAGGGAGGTTCACAGCAAGAGCACAGAAACTAGGGCCAGTGCCCGGTTGTGTGACCTTGAGTAAGTTCTTTTTCCCTT GAACAGGGAGAGAGACACAATGGATCAGAGTGTCTCTGCCAGTTCTAACTTGGGGATTCTAGTGGGTTGAACCGAACGGTAGTCCGTTTC CAAAAGAGGAAGCCAAGACCAGAGGGGGAGTGGTTCCTTCAAGTTTGCAGAACCAGTAAGTGGCAGAGCAGGACTCATATCTAGTTAGTG GTTCAGAGCATGGGCTCCGGAGCTAGACTGCCTGGATTTGAACCCTGGCTTTGCCACTTGCCTGTTGGGTGACTTTGGACAAGCTGCTTA AATTATGTCTCCATTTCCTAATCCACAGAACAAGTGTAATACTAGTTATCTGTTTCATGGAGTGATTGTGAGGATTAAATAAAGTTAATA >In-frame_FDPS_ENST00000356657_chr1_155282186_+_IPO9_ENST00000361565_chr1_201840289_+_9599nt GAGTACCCGCCAACAAGCGGGACCGAGCAGGAATCCGTATCTGGGAACAGGTGAGAGAGGATGTGTGCTGGGCCTTGGAGGAAGGGGGCC GAGACCGGGCCTTACTTCTGTAACGATACTGTGAGGCATCGGAAGGCCAGCCTGTTGTGTCCGTTTTGAAGGATGCCCCTGTCCCGCTGG TTGAGATCTGTGGGGGTCTTCCTGCTGCCAGCCCCCTACTGGGCACCCCGGGAGAGGTGGCTGGGTTCCCTACGGCGGCCCTCCCTGGTG CACGGGTACCCAGTCCTGGCCTGGCACAGTGCCCGCTGCTGGTGCCAAGCGTGGACAGAGGAACCTCGAGCCCTTTGCTCCTCCCTCAGA ATGAACGGAGACCAGAATTCAGATGTTTATGCCCAAGAAAAGCAGGATTTCGTTCAGCACTTCTCCCAGATCGTTAGGGTGCTGACTGAG GATGAGATGGGGCACCCAGAGATAGGAGATGCTATTGCCCGGCTCAAGGAGGTCCTGGAGTACAATGCCATTGGAGGCAAGTATAACCGG GGTTTGACGGTGGTAGTAGCATTCCGGGAGCTGGTGGAGCCAAGGAAACAGGATGCTGATAGTCTCCAGCGGGCCTGGACTGTGGGCTGG TGTGTGGAACTGTCCCTGATCATGGTGTTCGCTCATCTGGTGCACACTCAGCTAGAACCTCTCTTGGAGTTCCTGTGTAGCCTCCCAGGA CCTACTGGCAAACCTGCTCTAGAGTTTGTGATGGCTGAGTGGACAAGCCGACAGCACCTGTTCTATGGACAGTATGAAGGCAAAGTCAGC TCTGTGGCACTCTGTAAGCTGCTCCAGCATGGCATCAATGCAGATGACAAACGGCTACAGGATATCCGTGTGAAGGGAGAGGAGATCTAC AGCATGGATGAGGGCATCCGCACCCGCTCTAAGTCAGCCAAAAACCCAGAACGCTGGACAAACATTCCTTTGCTGGTCAAGATCCTAAAG CTGATCATCAACGAGCTCTCCAACGTCATGGAGGCTAATGCCGCTCGCCAGGCCACTCCTGCAGAGTGGAGTCAAGATGACTCCAATGAT ATGTGGGAGGACCAGGAGGAGGAAGAGGAGGAGGAGGAGGATGGTTTAGCTGGCCAACTTTTATCTGACATTCTTGCTACAAGTAAATAT GAGGAGGATTACTACGAGGATGATGAGGAAGATGACCCTGATGCCCTGAAGGATCCTCTCTATCAGATTGATCTGCAGGCATATCTCACA GATTTCCTCTGCCAGTTTGCTCAGCAGCCCTGCTACATAATGTTTTCAGGCCACCTTAATGACAATGAGAGGCGAGTTCTACAGACCATC GGCATCTAAAAAGGGGAGCCTTTCTACATTTGCTCCTTCTGGGCCAGCCGCAAACCATTTTGCAGCCCTCACTGGCCTTGAGATGCACTT TCTTCTCAACCTAAAGTGGCATCTTGACCCTTGGCCCTTGGCCTCGGCAGTGACACTGATGACAATTCAGACCAGGCTCACCGGTGCCGT CACTTAGGAATGCTGGAACAAAGGACATTTCTCAAAGTTCCCCTGAAGACATGCCATCTCTAGAACCTTTTTTCTCCCCGACTCTACCCC CACCTCTGTTCCTAGAGCCCTCTGCTGGCGAGTCCAGAAACATTATTGCCCAGAAGGATTATGTGTTTATGGATTATTTTGCCCCGCCTC AGGAGCGCAGGAAGTCACTACCATTTATATTCTAAAACAGACCTATCTATGTTCATAGGACTTCTGATGTGTTCAGATAGGAATCCTCAT GAGAGATCATTATGCTTTGTGCCCTGGACCACTGCTGCTCTGGGTTCTCAGGAGGAACAGGCAAGAGCAGCTTCATTCTAAGCCTTTCCA GTGACCTCAGCCTTGCTTCTCTTCTACAACACTAAGGCTCCTCTGTCAGAGGAGGTCGTCTTGTTTTTGCTTCATTGCATGACATAACCC TTCCCCTCAAGCTGTTCCTATATATACATGCACACACAAAATAAGCCAGACAGATGGCAATTTGATCTTCCTTTTTTAGAAAAAAAAAAA AAAATGGGGAAAAGGGATTTTTTTTAAATCCACCTGACCCAACTATATTTAATATGCCTCTCCCACACATTACCACAGAGTCTGATATTC AAAGGTTATCCCCTTTCCCTCAGGAAGCCTCTAAAGTGCTTAAGTTGTAGCCCTCAAATTTGCAACATGTATTTTTCTAGGACAGTAAAG TAATCTTTACAAATGAATTTAGTTGCATGGTATAAGGTGTCTCAGCACCTGTTTGCCTTCTATTCCCTTTAGAAGGTAAGTAAAAGTAAT GGGGGAAAGGATTAGGTGGAGCCTGTCTAAACATTCTAGTGTGTCTTGGCAAACATAGCCTGAAATGATTCTTAAAGAACTGGCATTGTT TAATCAAATATTTTTAAGGGAGATTCCTTAATTGGGAAGTTTAGTCTGTTTGGGGTTCAAAGAGTAAATGAGGATTAGAAAATCATGGAG AGAGGCTGGGCGCGGTGGCTAACGCCTGTAATCCTAGCACTTTGGGAGGCTGAGATGGGCGGATCACTTGAGATCAGGAGTTTGAGGCTA GCCTGGCCAACACAGTGAAACCTGCATTTCTACTAAAAATACAAAAATTAGCTGGGCATGGTGGTGCATGCCTGTAATCCCAGTTAACTT GAGATGCTGAGGCAGGAGAATCGCTTGAACTTGGGAAGCAGAGGTTGCAGTGAACCGATATCACACCGTTGCATTCCAAGGCAAGACTCA ATCACACACACACACACACACACACACAAATCATGGGGAGAAAGATGAAACCTGTGTTCCCCTTTTTTTGGTAGTGCCCACATCTGGTGC CCCATTTTTAATAACCACAGGATATTTCTTTAGATTGATATTCTCACAAAGAAGAAATAGAATATAGGCTGGGCGTGGTGTGTCACACCT GTAATCCCAGCACTTACGGAGGCCGAAGCCAGCGGATCACCAGAGGTCAGGAGTTCGAGACCAGCCTGACCAACATGATGAAACCCTGTC TCTACTAAAAATACAAAAATTAGCCAGGCATGGTGGCATGCACTTGTAATCCCAGCTACTCGGGAGGCTGAGACAGGAGAATCGCTTGAA CCTGGGAGGCAGAGGTTGCAGTAAGCCAAGATCGCACCATTGCACTACAGCCTGGGCAACAAGAGGAGCGAAACTCTGTCTCAAAAAAAA AAAAGAGAAAGAATATAAAGTGAATCTGAATCTCCACTCAAGGGGATGGCCCCAAGGATATTGTAGCTGGTAATTTCTTCATGCCACTAG GTGTCCCCAGTGTTCAACCTCCATGACTGAGATTGGAAGAAGTAGAGTTAAAAGTTTTTACTACCTTTGAGAAGCCTGCGGGCATGTTCA CAGTCGTCCCATGCCAGCCAGGTTCTGAGGCTAACTGCTTGTGCCCCTGCTGCTTCACATGGCATTGTGGGAGTTGCTGATACTGGGGAA ATGATGGCAGATCTGACCAAGTGGTGCTGAGAAAACCACCCTCGGCCTTGCAGACTCCATAGTTTATCTCAAGGCAGTGCCAGTCGGATT TGGTGCTAAAGGCATAAGGCCAAGTCAGCCTCTGATATTGGCACAAAAGAATGGTCTCATGCCAGTAGCATTGAACTGCTGAGCTTGGGA AGGCTTAAGGCTCCCACACACAGACTGAGAATGATGGGGGTCCCTCTGCGTCTGCTAATTAGACAAACATTCTATATCTAGTGCCAAAAG TGGTCCTAAATCCTTTGGCAAGGGTCCTTTCTGCTCTCATGCTGATTTGGGGGAGGACTGGGCATCCTGCCTCAGGAGAACTTGAGTCCT GAGGAAAGGGCCCTAGTAACACTTAAGGGCTACCCCTGGCTAACAGATACTCGGCTGTGGGTGAGAGCAGAAGGTCTTGGACCCCTCGAT GTGCAGGTACTTAATTGTGTTTCCAGTGCATTTTCATATACATTATCCCATTTAACCTTTATAACAGGTTCACAGAGTGGATATTCCCAT TCTGTTGATGAGAAAAAGAGTGGAGAGACTGTGTCCAGTGTCAGCAGGAAGAAAAAAGATCTGTTGGAGGCCAGTACATGTTGACAGAAA CTCTAGACCATATTTTGTCTCCTGTCTTTGGCCAAAGAGAACTAGCTTCAGTCTGAAAAGGGCAGGGCTAAGTGGTTACAAGGAACTAAA AAGTTCAAGGTAAGACAAATGAGGTAAAAATAAAAAAGAGCACTTAGCTGCTCTGAGACATTTTAGTCTCCTGACTGGTAAACAGCAGCT GGGGCACCAAGGGGCTCCCAGGAGTTTGTCGAGCTTTTATTGGAGTGAACTGAAAGGAAAATGGAAGGAATGCTATAAGACTGAAAAGAA GTTAAAGCCCTAGGAAGGAAGCTGATAACACAAGTTACAGACGTATATGTGACATTGATTTGGGAGAATGAACCTACAACAAATGACCCA AAAGCACCTAAATAAGAGTGACGAGAGTTTAACAGACATTCATTATGGACTTCAGAGAAAATGATGCTAAACTGGTCTTAGAATCTTCTT TAATTTTGTTAACTAGGTAAATAATCTGGACATTTTAGTCAAAGCATTAGACAGACAGAGAAGTTGGTAACTGACCACTAACTAACAAAC TATAAATTCACCCATTGTGGGTTGACCTGGTAAGTTCCCCCAGGGCTGTGTCCTTGGCCCCTCCTTTGATATTAGTGACAGATGACTTTT TTTATGCCTTACCCATTCCACAAAAGAATTTGAAGCCATTTACACAAGAGATAGTACTAGTAAATTAGGAGTGCTGATCAAATTTTTAGA TAATAAGAAACCCTTAGGAAGGATGACAATTTAGAATCCAAATTTAGGATCCAAACAAATACCATTACAAACTATAAAAATGAGCAGAAT CTAAATGTAACATTTCAATAAATGCAGATTGATAATAACATCTGTGCAGAGTTGAGGACTATAGAGTACTGTGCTGTCACTAACAGTATT GTGTGCTACTAAGAGTTTAATGGCTGGGTGTGGTGGCTCACACCTGTAATCCCAACACTTTGGGAGGCCTAGGTGGGTAAATCAGCTGAG ATCAGGAGTTCGAGACCAGCCTGGCCAATGTGGTGAAACCCCGCCTCTACTAAAAATAAAAAAATTAGCTGGGCATGGTGGCACGTGCCT GTAATCCCAGCTACTCGGGAGGCTGAGGCGGGAGAATCACTTGAACCTGGGAGACAGAGGTTGCAGTGAGTCGAGATCACACCATTGCAC TCCAGCCTGGGCAACAGAGCAAGATTCTGTCTCAAAAAATAAAGTTTATTATGCCAGGAGGGCCAGGTGTGGTGCCACACCCATGTAATC CCAGCACTTTAGGAGGCTGAGGAGGGCAGATCACTTAAGCCCAAGAGTTTGAGACCAGTCTGGGCAATGTGGCAATACCTTGTCTCTTAA AATTTAAAATAAAAAAAAAGTTTATTATGCCAGGAACTGTTAATGTGTCCAAAAAAACTCCAGTGTGGTTCTAGGATGAGATAATAAAAA CAGGTTGTCTAGGGTAGTGTGGAAGGTCCTTTCAGTCTTCCTGTGCCTATCAGTGATCCTCATTGCCATGTTCCCTTCTGGTGCTCAACC GGAGGCTCCCTGACAGATGAGTCCTCTGCCAGAGGAAGGCTAAGATGTAGAGGACAAATCGTGTCAAGGAAAAGAAGCTTGAAGGAGCTA AGAATGCTTAGCTTAGAGAAGACAAGAGGAAACAGGACATGGCTTTGGGAAGTTCAAGGATGGTCCAGTGAAATACATACTATACTTTTG CACCCCAGCTAAGCTGACCCATGATCAGTAAGTAGGAAATAAAAGGCCAATTTCTGGCTACTCTTGCCCCCAACCCCATTTCAGTGAACT ATGAACCTCTATTAGATATGCAAGGCCGGTGCTAAATGCTGGAGGGCTTTGGCCCTTTCCCTCAAGGAGCTAGTCTAGTAGGGGGTCAGA AATACAGATGGGCCTGAACATAATGATGGTTTGACTTCCAGTTTTTCAACTTTAGGATTGTGCAAAAGCTATACACATTCGGTAGAAACA GTACTTCAAGTATCCATACAATCAGTACAGTATTCAATAAATTACATGAGACATTCAACACTTTATTATAAAATAGGCTTTGTGTTAGAT GAGTTTGCCCAACTGTAAGCTAATGTAAGTGATCTGAGTAGGTTTAAGGTAGCCTAGGTGTATTAAATGCATTTTTCACTTAACGGTATT TTCAACTTTTGTTGGGTTTATTGGGATGTAGCCCCATTATAAGCTGAAAAGCATCTGTAGTATAATAAATGTGGGGAGTGCTGTGAGAGA AATAAGTGTACTGGGTTTAGTTCCCACTGCCCAAAAAAGGAACTGGCTAATGGTAACCTGGGGGAGGAAGTCGGGTAAGTTGCATGGAGA AGGCAACCCTTGAACACTTGCAAGGAGCTAACAATACCTGCTTCTGGAGTATTTAAACGCCAGTGGGTATGCTAAATACTTTTACCTCAG ACCACCTACTAACCTTACAAAGTAGTCCACTTTGCTCACCCAGTTTTACAGATTGATGAAACTGAAGCAGACAGATATTGTTAACCTATC AAAGGTCACCCTGCAAGTGTGTGATTATAGTCCAAGCAGCTTGTACTTGTTGCCTATTTGTTTTGCCTTTCCTGTGCATTTGCCAGGCAG ATGAGAGTGGGGTAAGACATTGCAGAGAAAAAGTAAGAAAAGGCCGTCATGAAACAATTTCATTTTCAGACCTTATAAGCACGTTACAAG TACTGATATTTATGCTTAAGTTCACGGGAGTCCTGGCCAGAAATAAAGCTGGAAGGACAAGTGGGGGGCAGATTGTGAAGGATCCTTCAA GACCTGCTTCCTCTAGAGAATGGGAGACTACCCAAGATAACTAAACAGGGAAGTGATCAGGTTTTGTGTCTTAGAAAAGTGTTGCAGTGT TGATGCAAATGTGACTAGAAGGGTGACTTGGAACCTGGATTGAAGGGGTGGGAGATGGGAGAAAGGAATGCAGTCTGGCAGCAGCTACAG CAGTCCAGGTGGGAAAACCCAGAGCCTGAACTAAGGTTGTAACTAGAGGGGATAGGGTGGAAGAGCTGGATTAGAGATGTTGACAAGATA AAGTCAGTAGGACTTAAAGACTGACAAGTAAGGATTTTCCAAAAGTGAGAGCTGTGGAATGAATTGTCTTAAAATGTTGCAGTGAGTTCC TCCTCATCAATCCAAGTGCTCGATCAGAGGCTAGACCTTTAGTTAGCAGTCACGGGAAAATTCCCCATTCTCACGGGGATTTAGACTAGG TCTTAACCATACTTTACCAAGATTCCAGTAGCAAAGCACCCAAAAGTAATCGCAATAAAATTCCAATTTTTGTAGGCCGGGCATAGTGGC TCACACCTGTAATCCCAGCACTTTGGGAGGCCGAGGCAGGCGGACCACGACATCAAGAGTTCAAGAGCAGCCTGGCCAGCATGGTGAAAC CCCGTCTCTACTAAAAATACAAAAAAATTAGCTGGGCATGGTGGCGCATGCCTATAATCCTAGCTACTCAGGCAGCTGAAGCAGGAGAAT TGCTTGAACCCGGGAGGCAGAGGTTGCAGTGAGCCAAGATCATGCCACTACACTCCAGCCTGGGCGACAGAGCGACACTCTGCCTCAAAA AAAAAAAAAAACAAAAAAAAAAACAAGTTTTGTGAATTTAAGTTTCCCTAATGGATGGTACAGGTCAACATTTGCCATCTAATGACACTT ACATTCCAGTTTTTTCCTTTTTTGAGTAACTGGGAAAAGGGTGGCATTACTGCTGGCTTCCTAAAATTGAAAAGTATACTAGGGTTTTTA AACCTGTGTAGAATACATGATATGGTAGCAAATGTGCTGTAGGAAGAAAAGCAATGAGGAACTACTGGCCTGACTAGGAGGCCTAGAAGT CCCTCCCAGGCTTGAGTTGTTCTGACTTGGCATGATTACATAGCTGCGGCAAGTGACGTTTCCTTCAAGCCTTGGTTCCCTCATCTGTAA AATAGGGAACTAATACCTACCTCACAGGATTGTAGTTAGAATTAAGGATGACTTCATTAAAGCACCTCTAGTGGTGGAAGATGTCCCATC CTATCCCCCACCCATAGCTGGGAGCTATGTTTGGCTCATTCTTCCTGACTCACTGGATTACACTGTGACTCAGTTCAATTTCACACATGC TGCTGCTAAATTAGGGTCTTGGTGAGCCTTTGGGAGGACAGCTCTGAGGAATGAATTGTAGCACTGCAGCCCTGCCTGAGGAACATGATA GAAACAGGTGGTAGGCCCAGCTCTTGCCTTCCACCTACTAAGCAGTTTTTCTGTGGTTAGCTGTGTGACATAAACTATCGGTGTATTAAT TTGCTTTCACTAGATTCCCCCCCCCCCAACAACTTAGTCCAAGAACATACCTGAATTCTTTGCATTTCCTTGCCTTAGTTGCTTTTGTAG GGTGGACAGCAGGACTGCATGAGAATAGCTGTGCTTCTGGACCCTATGGTGAAAGCTCTAGTGAACTGCAATTAGGCCCAGGGTCCCGGA GGAAGAAGGGGAGAGAAAAAGGGGGGTAGTTTTCCAAAAGATAAGTAGGGGACAAAAAAGTCCACGGGGCCTATGAGCGGTGAGACTCCT GCCCTGATTGTGGCAAAGCACCTGGAGATGATAGAACTTCCTAGGGAAAAGGCTGCATGGAGTCCCCAGGGATGCTGGGCCCTGGTCACC AAGGCTCCCTGGGAAGGTCTCTTGTACCTGGGGCACACAGACCAACACTTCTGAATTTGCAAGCTTAAGAGCATGTATGAGCAGAACCTG TGCAGACCAAGGCTTAGAGGGCTCACCTCAATGTTTTGCACTGTGTGAGACCCCAGGACCTTTTCGTGATTCTGGAGAGGGGAACAAACC ATAATAACAACAAACCAGGTAGCAGGATAGAGACTCATTCTCATCTATTTTGGTTAAAAGAAAATAAATGTATTTCTTCCACACCTGATT TTGTGATTGCAAATTCATAACTAATATCCCTCGTCAGCTCCGCTGACTCATCCCTGCCACAGGGAGGTTCACAGCAAGAGCACAGAAACT AGGGCCAGTGCCCGGTTGTGTGACCTTGAGTAAGTTCTTTTTCCCTTGAACAGGGAGAGAGACACAATGGATCAGAGTGTCTCTGCCAGT TCTAACTTGGGGATTCTAGTGGGTTGAACCGAACGGTAGTCCGTTTCCAAAAGAGGAAGCCAAGACCAGAGGGGGAGTGGTTCCTTCAAG TTTGCAGAACCAGTAAGTGGCAGAGCAGGACTCATATCTAGTTAGTGGTTCAGAGCATGGGCTCCGGAGCTAGACTGCCTGGATTTGAAC CCTGGCTTTGCCACTTGCCTGTTGGGTGACTTTGGACAAGCTGCTTAAATTATGTCTCCATTTCCTAATCCACAGAACAAGTGTAATACT |
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FusionGenePPI for FDPS_IPO9 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| FDPS | FGFR1, ATXN1, EIF4ENIF1, EGFR, ADSS, SORD, STAMBP, IDH1, NME1, NME1-NME2, PLS3, TALDO1, MOV10, NXF1, ABCE1, BASP1, CLIC4, DPH2, AIFM3, CTH, G6PD, HNRNPA1, HNRNPA1L2, HNRNPA3, HSPA8, IGF1R, PABPC1, PLAA, SEC31A, XPO1, GARS, SEPHS1, TTC38, NTRK1, CREB3, PPME1, PDSS2, PCYOX1, CLPP, ZMPSTE24, CDC27, TTC19, PDSS1, ALAS1, PSME4, MMAB, ATPAF2, NDUFAF5, GLDC, TRIM25 | IPO9 | USP49, MEPCE, RPAP1, PMS1, MYC, APP, NAP1L1, KPNB1, ECT2, CA9, CFTR, NPM1, EGFR, GNPDA1, HMGB3, HEXB, MCTS1, PDCD6IP, SRP14, TNPO3, TUFM, TWF1, USP5, NOL3, PLIN3, TNPO1, FAF2, ADORA3, VTI1B, COMTD1, TNFSF13B, PNKD, PTGER3, HIST1H2BA, UNK, IPO7, CAND1, CANX, COPB1, EPRS, HSP90B1, IDH3A, IPO5, IPO8, KPNA3, KPNA4, POLR3A, POLR3B, PRKCSH, PSMD2, RAB1A, RAN, RCN1, RPN2, SMARCA5, SSR4, XPO1, RPN1, NTRK1, HIST1H2BG, RPGRIP1L, DCTN1, CEP19, RPGRIP1, CENPJ, SORT1, XRCC3, USP37, SNW1, CDC5L, ZNF746, PTPMT1, H2AFX, SIGLECL1, H2AFY2, TMEM206, AKIRIN2, CHRM4, CHRM3, FZD10, HTR2C, KLHDC2, BROX, PTPRE, STOM, MTNR1A, MTNR1B |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for FDPS_IPO9 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
| Hgene | FDPS | P14324 | DB00282 | Pamidronate | Farnesyl pyrophosphate synthase | small molecule | approved |
| Hgene | FDPS | P14324 | DB00399 | Zoledronic acid | Farnesyl pyrophosphate synthase | small molecule | approved |
| Hgene | FDPS | P14324 | DB00630 | Alendronic acid | Farnesyl pyrophosphate synthase | small molecule | approved |
| Hgene | FDPS | P14324 | DB00710 | Ibandronate | Farnesyl pyrophosphate synthase | small molecule | approved|investigational |
| Hgene | FDPS | P14324 | DB00884 | Risedronate | Farnesyl pyrophosphate synthase | small molecule | approved|investigational |
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RelatedDiseases for FDPS_IPO9 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | FDPS | C4225262 | POROKERATOSIS 9, MULTIPLE TYPES | 1 | UNIPROT |
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