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Center for Computational Systems Medicine
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FusionGeneSummary

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FusionProtFeature

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FusionGeneSequence

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FusionGenePPI

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RelatedDiseases

Fusion gene ID: 13296

FusionGeneSummary for FDPS_IPO9

check button Fusion gene summary
Fusion gene informationFusion gene name: FDPS_IPO9
Fusion gene ID: 13296
HgeneTgene
Gene symbol

FDPS

IPO9

Gene ID

2224

55705

Gene namefarnesyl diphosphate synthaseimportin 9
SynonymsFPPS|FPS|POROK9Imp9
Cytomap

1q22

1q32.1

Type of geneprotein-codingprotein-coding
Descriptionfarnesyl pyrophosphate synthase(2E,6E)-farnesyl diphosphate synthaseFPP synthaseFPP synthetasefarnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferaseimportin-9ran-binding protein 9ranBP9
Modification date2018052320180523
UniProtAcc

P14324

Q96P70

Ensembl transtripts involved in fusion geneENST00000447866, ENST00000368356, 
ENST00000487002, ENST00000356657, 
ENST00000361565, ENST00000464348, 
Fusion gene scores* DoF score4 X 4 X 2=325 X 5 X 3=75
# samples 45
** MAII scorelog2(4/32*10)=0.321928094887362
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
log2(5/75*10)=-0.584962500721156
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: FDPS [Title/Abstract] AND IPO9 [Title/Abstract] AND fusion [Title/Abstract]

Functional or gene categories assigned by FusionGDB annotation
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check button Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
Data typeSourceCancer typeSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
TCGARVPRADTCGA-J4-A67Q-01AFDPSchr1

155282186

+IPO9chr1

201840289

+
* LD: Li Ding group's fusion gene list
  RV: Roel Verhaak group's fusion gene list
  ChiTaRs fusion database

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000447866ENST00000361565FDPSchr1

155282186

+IPO9chr1

201840289

+
5CDS-intronENST00000447866ENST00000464348FDPSchr1

155282186

+IPO9chr1

201840289

+
In-frameENST00000368356ENST00000361565FDPSchr1

155282186

+IPO9chr1

201840289

+
5CDS-intronENST00000368356ENST00000464348FDPSchr1

155282186

+IPO9chr1

201840289

+
3UTR-3CDSENST00000487002ENST00000361565FDPSchr1

155282186

+IPO9chr1

201840289

+
3UTR-intronENST00000487002ENST00000464348FDPSchr1

155282186

+IPO9chr1

201840289

+
In-frameENST00000356657ENST00000361565FDPSchr1

155282186

+IPO9chr1

201840289

+
5CDS-intronENST00000356657ENST00000464348FDPSchr1

155282186

+IPO9chr1

201840289

+

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FusionProtFeatures for FDPS_IPO9


check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
FDPS

P14324

IPO9

Q96P70

Key enzyme in isoprenoid biosynthesis which catalyzesthe formation of farnesyl diphosphate (FPP), a precursor forseveral classes of essential metabolites including sterols,dolichols, carotenoids, and ubiquinones. FPP also serves assubstrate for protein farnesylation and geranylgeranylation.Catalyzes the sequential condensation of isopentenyl pyrophosphatewith the allylic pyrophosphates, dimethylallyl pyrophosphate, andthen with the resultant geranylpyrophosphate to the ultimateproduct farnesyl pyrophosphate.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

.

* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneIPO9chr1:155282186chr1:201840289ENST00000361565+172443_1198031042DomainImportin N-terminal


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FusionGeneSequence for FDPS_IPO9


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.
>In-frame_FDPS_ENST00000447866_chr1_155282186_+_IPO9_ENST00000361565_chr1_201840289_+_333aa
MNGDQNSDVTAQEKQDFVQHFSQIVRVLTEDEMGHPEIGDAIARLKEVLEYNAIGGKTNRGLTVVVAFRELVEPRKQDADSLQRAWTVGW
CVELSLIMVFAHLVHTQLEPLLEFLCSLPGPTGKPALEFVMAEWTSRQHLFTGQTEGKVSSVALCKLLQHGINADDKRLQDIRVKGEEIY
SMDEGIRTRSKSAKNPERWTNIPLLVKILKLIINELSNVMEANAARQATPAEWSQDDSNDMWEDQEEEEEEEEDGLAGQLLSDILATSKT

>In-frame_FDPS_ENST00000368356_chr1_155282186_+_IPO9_ENST00000361565_chr1_201840289_+_399aa
MPLSRWLRSVGVFLLPAPYWAPRERWLGSLRRPSLVHGYPVLAWHSARCWCQAWTEEPRALCSSLRMNGDQNSDVTAQEKQDFVQHFSQI
VRVLTEDEMGHPEIGDAIARLKEVLEYNAIGGKTNRGLTVVVAFRELVEPRKQDADSLQRAWTVGWCVELSLIMVFAHLVHTQLEPLLEF
LCSLPGPTGKPALEFVMAEWTSRQHLFTGQTEGKVSSVALCKLLQHGINADDKRLQDIRVKGEEIYSMDEGIRTRSKSAKNPERWTNIPL
LVKILKLIINELSNVMEANAARQATPAEWSQDDSNDMWEDQEEEEEEEEDGLAGQLLSDILATSKTEEDYYEDDEEDDPDALKDPLTQID

>In-frame_FDPS_ENST00000356657_chr1_155282186_+_IPO9_ENST00000361565_chr1_201840289_+_399aa
MPLSRWLRSVGVFLLPAPYWAPRERWLGSLRRPSLVHGYPVLAWHSARCWCQAWTEEPRALCSSLRMNGDQNSDVTAQEKQDFVQHFSQI
VRVLTEDEMGHPEIGDAIARLKEVLEYNAIGGKTNRGLTVVVAFRELVEPRKQDADSLQRAWTVGWCVELSLIMVFAHLVHTQLEPLLEF
LCSLPGPTGKPALEFVMAEWTSRQHLFTGQTEGKVSSVALCKLLQHGINADDKRLQDIRVKGEEIYSMDEGIRTRSKSAKNPERWTNIPL
LVKILKLIINELSNVMEANAARQATPAEWSQDDSNDMWEDQEEEEEEEEDGLAGQLLSDILATSKTEEDYYEDDEEDDPDALKDPLTQID


* Fusion transcript sequences (only coding sequence (CDS) region).
>In-frame_FDPS_ENST00000447866_chr1_155282186_+_IPO9_ENST00000361565_chr1_201840289_+_999nt
ATGAACGGAGACCAGAATTCAGATGTTTATGCCCAAGAAAAGCAGGATTTCGTTCAGCACTTCTCCCAGATCGTTAGGGTGCTGACTGAG
GATGAGATGGGGCACCCAGAGATAGGAGATGCTATTGCCCGGCTCAAGGAGGTCCTGGAGTACAATGCCATTGGAGGCAAGTATAACCGG
GGTTTGACGGTGGTAGTAGCATTCCGGGAGCTGGTGGAGCCAAGGAAACAGGATGCTGATAGTCTCCAGCGGGCCTGGACTGTGGGCTGG
TGTGTGGAACTGTCCCTGATCATGGTGTTCGCTCATCTGGTGCACACTCAGCTAGAACCTCTCTTGGAGTTCCTGTGTAGCCTCCCAGGA
CCTACTGGCAAACCTGCTCTAGAGTTTGTGATGGCTGAGTGGACAAGCCGACAGCACCTGTTCTATGGACAGTATGAAGGCAAAGTCAGC
TCTGTGGCACTCTGTAAGCTGCTCCAGCATGGCATCAATGCAGATGACAAACGGCTACAGGATATCCGTGTGAAGGGAGAGGAGATCTAC
AGCATGGATGAGGGCATCCGCACCCGCTCTAAGTCAGCCAAAAACCCAGAACGCTGGACAAACATTCCTTTGCTGGTCAAGATCCTAAAG
CTGATCATCAACGAGCTCTCCAACGTCATGGAGGCTAATGCCGCTCGCCAGGCCACTCCTGCAGAGTGGAGTCAAGATGACTCCAATGAT
ATGTGGGAGGACCAGGAGGAGGAAGAGGAGGAGGAGGAGGATGGTTTAGCTGGCCAACTTTTATCTGACATTCTTGCTACAAGTAAATAT
GAGGAGGATTACTACGAGGATGATGAGGAAGATGACCCTGATGCCCTGAAGGATCCTCTCTATCAGATTGATCTGCAGGCATATCTCACA
GATTTCCTCTGCCAGTTTGCTCAGCAGCCCTGCTACATAATGTTTTCAGGCCACCTTAATGACAATGAGAGGCGAGTTCTACAGACCATC

>In-frame_FDPS_ENST00000368356_chr1_155282186_+_IPO9_ENST00000361565_chr1_201840289_+_1197nt
ATGCCCCTGTCCCGCTGGTTGAGATCTGTGGGGGTCTTCCTGCTGCCAGCCCCCTACTGGGCACCCCGGGAGAGGTGGCTGGGTTCCCTA
CGGCGGCCCTCCCTGGTGCACGGGTACCCAGTCCTGGCCTGGCACAGTGCCCGCTGCTGGTGCCAAGCGTGGACAGAGGAACCTCGAGCC
CTTTGCTCCTCCCTCAGAATGAACGGAGACCAGAATTCAGATGTTTATGCCCAAGAAAAGCAGGATTTCGTTCAGCACTTCTCCCAGATC
GTTAGGGTGCTGACTGAGGATGAGATGGGGCACCCAGAGATAGGAGATGCTATTGCCCGGCTCAAGGAGGTCCTGGAGTACAATGCCATT
GGAGGCAAGTATAACCGGGGTTTGACGGTGGTAGTAGCATTCCGGGAGCTGGTGGAGCCAAGGAAACAGGATGCTGATAGTCTCCAGCGG
GCCTGGACTGTGGGCTGGTGTGTGGAACTGTCCCTGATCATGGTGTTCGCTCATCTGGTGCACACTCAGCTAGAACCTCTCTTGGAGTTC
CTGTGTAGCCTCCCAGGACCTACTGGCAAACCTGCTCTAGAGTTTGTGATGGCTGAGTGGACAAGCCGACAGCACCTGTTCTATGGACAG
TATGAAGGCAAAGTCAGCTCTGTGGCACTCTGTAAGCTGCTCCAGCATGGCATCAATGCAGATGACAAACGGCTACAGGATATCCGTGTG
AAGGGAGAGGAGATCTACAGCATGGATGAGGGCATCCGCACCCGCTCTAAGTCAGCCAAAAACCCAGAACGCTGGACAAACATTCCTTTG
CTGGTCAAGATCCTAAAGCTGATCATCAACGAGCTCTCCAACGTCATGGAGGCTAATGCCGCTCGCCAGGCCACTCCTGCAGAGTGGAGT
CAAGATGACTCCAATGATATGTGGGAGGACCAGGAGGAGGAAGAGGAGGAGGAGGAGGATGGTTTAGCTGGCCAACTTTTATCTGACATT
CTTGCTACAAGTAAATATGAGGAGGATTACTACGAGGATGATGAGGAAGATGACCCTGATGCCCTGAAGGATCCTCTCTATCAGATTGAT
CTGCAGGCATATCTCACAGATTTCCTCTGCCAGTTTGCTCAGCAGCCCTGCTACATAATGTTTTCAGGCCACCTTAATGACAATGAGAGG

>In-frame_FDPS_ENST00000356657_chr1_155282186_+_IPO9_ENST00000361565_chr1_201840289_+_1197nt
ATGCCCCTGTCCCGCTGGTTGAGATCTGTGGGGGTCTTCCTGCTGCCAGCCCCCTACTGGGCACCCCGGGAGAGGTGGCTGGGTTCCCTA
CGGCGGCCCTCCCTGGTGCACGGGTACCCAGTCCTGGCCTGGCACAGTGCCCGCTGCTGGTGCCAAGCGTGGACAGAGGAACCTCGAGCC
CTTTGCTCCTCCCTCAGAATGAACGGAGACCAGAATTCAGATGTTTATGCCCAAGAAAAGCAGGATTTCGTTCAGCACTTCTCCCAGATC
GTTAGGGTGCTGACTGAGGATGAGATGGGGCACCCAGAGATAGGAGATGCTATTGCCCGGCTCAAGGAGGTCCTGGAGTACAATGCCATT
GGAGGCAAGTATAACCGGGGTTTGACGGTGGTAGTAGCATTCCGGGAGCTGGTGGAGCCAAGGAAACAGGATGCTGATAGTCTCCAGCGG
GCCTGGACTGTGGGCTGGTGTGTGGAACTGTCCCTGATCATGGTGTTCGCTCATCTGGTGCACACTCAGCTAGAACCTCTCTTGGAGTTC
CTGTGTAGCCTCCCAGGACCTACTGGCAAACCTGCTCTAGAGTTTGTGATGGCTGAGTGGACAAGCCGACAGCACCTGTTCTATGGACAG
TATGAAGGCAAAGTCAGCTCTGTGGCACTCTGTAAGCTGCTCCAGCATGGCATCAATGCAGATGACAAACGGCTACAGGATATCCGTGTG
AAGGGAGAGGAGATCTACAGCATGGATGAGGGCATCCGCACCCGCTCTAAGTCAGCCAAAAACCCAGAACGCTGGACAAACATTCCTTTG
CTGGTCAAGATCCTAAAGCTGATCATCAACGAGCTCTCCAACGTCATGGAGGCTAATGCCGCTCGCCAGGCCACTCCTGCAGAGTGGAGT
CAAGATGACTCCAATGATATGTGGGAGGACCAGGAGGAGGAAGAGGAGGAGGAGGAGGATGGTTTAGCTGGCCAACTTTTATCTGACATT
CTTGCTACAAGTAAATATGAGGAGGATTACTACGAGGATGATGAGGAAGATGACCCTGATGCCCTGAAGGATCCTCTCTATCAGATTGAT
CTGCAGGCATATCTCACAGATTTCCTCTGCCAGTTTGCTCAGCAGCCCTGCTACATAATGTTTTCAGGCCACCTTAATGACAATGAGAGG


* Fusion transcript sequences (Full-length transcript).
>In-frame_FDPS_ENST00000447866_chr1_155282186_+_IPO9_ENST00000361565_chr1_201840289_+_9458nt
TCAGCGCGGCTCATCTTCGCCCAGCCAGGACACGCAGGATCGCGTTATCTGTCCCTCCCGCGGGCACATTGGGAGTTGTAGTCTAATTAT
ATATTTCCGCCCTTAGTGTGGGGAGAGCGGGAACTACTCGACCCACAGAGCCGATCGCGGAGCGGATTCTGCTTTTAGGAGTACCCGCCA
ACAAGCGGGACCGAGCAGGAATCCGTATCTGGGAACAGAATGAACGGAGACCAGAATTCAGATGTTTATGCCCAAGAAAAGCAGGATTTC
GTTCAGCACTTCTCCCAGATCGTTAGGGTGCTGACTGAGGATGAGATGGGGCACCCAGAGATAGGAGATGCTATTGCCCGGCTCAAGGAG
GTCCTGGAGTACAATGCCATTGGAGGCAAGTATAACCGGGGTTTGACGGTGGTAGTAGCATTCCGGGAGCTGGTGGAGCCAAGGAAACAG
GATGCTGATAGTCTCCAGCGGGCCTGGACTGTGGGCTGGTGTGTGGAACTGTCCCTGATCATGGTGTTCGCTCATCTGGTGCACACTCAG
CTAGAACCTCTCTTGGAGTTCCTGTGTAGCCTCCCAGGACCTACTGGCAAACCTGCTCTAGAGTTTGTGATGGCTGAGTGGACAAGCCGA
CAGCACCTGTTCTATGGACAGTATGAAGGCAAAGTCAGCTCTGTGGCACTCTGTAAGCTGCTCCAGCATGGCATCAATGCAGATGACAAA
CGGCTACAGGATATCCGTGTGAAGGGAGAGGAGATCTACAGCATGGATGAGGGCATCCGCACCCGCTCTAAGTCAGCCAAAAACCCAGAA
CGCTGGACAAACATTCCTTTGCTGGTCAAGATCCTAAAGCTGATCATCAACGAGCTCTCCAACGTCATGGAGGCTAATGCCGCTCGCCAG
GCCACTCCTGCAGAGTGGAGTCAAGATGACTCCAATGATATGTGGGAGGACCAGGAGGAGGAAGAGGAGGAGGAGGAGGATGGTTTAGCT
GGCCAACTTTTATCTGACATTCTTGCTACAAGTAAATATGAGGAGGATTACTACGAGGATGATGAGGAAGATGACCCTGATGCCCTGAAG
GATCCTCTCTATCAGATTGATCTGCAGGCATATCTCACAGATTTCCTCTGCCAGTTTGCTCAGCAGCCCTGCTACATAATGTTTTCAGGC
CACCTTAATGACAATGAGAGGCGAGTTCTACAGACCATCGGCATCTAAAAAGGGGAGCCTTTCTACATTTGCTCCTTCTGGGCCAGCCGC
AAACCATTTTGCAGCCCTCACTGGCCTTGAGATGCACTTTCTTCTCAACCTAAAGTGGCATCTTGACCCTTGGCCCTTGGCCTCGGCAGT
GACACTGATGACAATTCAGACCAGGCTCACCGGTGCCGTCACTTAGGAATGCTGGAACAAAGGACATTTCTCAAAGTTCCCCTGAAGACA
TGCCATCTCTAGAACCTTTTTTCTCCCCGACTCTACCCCCACCTCTGTTCCTAGAGCCCTCTGCTGGCGAGTCCAGAAACATTATTGCCC
AGAAGGATTATGTGTTTATGGATTATTTTGCCCCGCCTCAGGAGCGCAGGAAGTCACTACCATTTATATTCTAAAACAGACCTATCTATG
TTCATAGGACTTCTGATGTGTTCAGATAGGAATCCTCATGAGAGATCATTATGCTTTGTGCCCTGGACCACTGCTGCTCTGGGTTCTCAG
GAGGAACAGGCAAGAGCAGCTTCATTCTAAGCCTTTCCAGTGACCTCAGCCTTGCTTCTCTTCTACAACACTAAGGCTCCTCTGTCAGAG
GAGGTCGTCTTGTTTTTGCTTCATTGCATGACATAACCCTTCCCCTCAAGCTGTTCCTATATATACATGCACACACAAAATAAGCCAGAC
AGATGGCAATTTGATCTTCCTTTTTTAGAAAAAAAAAAAAAAATGGGGAAAAGGGATTTTTTTTAAATCCACCTGACCCAACTATATTTA
ATATGCCTCTCCCACACATTACCACAGAGTCTGATATTCAAAGGTTATCCCCTTTCCCTCAGGAAGCCTCTAAAGTGCTTAAGTTGTAGC
CCTCAAATTTGCAACATGTATTTTTCTAGGACAGTAAAGTAATCTTTACAAATGAATTTAGTTGCATGGTATAAGGTGTCTCAGCACCTG
TTTGCCTTCTATTCCCTTTAGAAGGTAAGTAAAAGTAATGGGGGAAAGGATTAGGTGGAGCCTGTCTAAACATTCTAGTGTGTCTTGGCA
AACATAGCCTGAAATGATTCTTAAAGAACTGGCATTGTTTAATCAAATATTTTTAAGGGAGATTCCTTAATTGGGAAGTTTAGTCTGTTT
GGGGTTCAAAGAGTAAATGAGGATTAGAAAATCATGGAGAGAGGCTGGGCGCGGTGGCTAACGCCTGTAATCCTAGCACTTTGGGAGGCT
GAGATGGGCGGATCACTTGAGATCAGGAGTTTGAGGCTAGCCTGGCCAACACAGTGAAACCTGCATTTCTACTAAAAATACAAAAATTAG
CTGGGCATGGTGGTGCATGCCTGTAATCCCAGTTAACTTGAGATGCTGAGGCAGGAGAATCGCTTGAACTTGGGAAGCAGAGGTTGCAGT
GAACCGATATCACACCGTTGCATTCCAAGGCAAGACTCAATCACACACACACACACACACACACACAAATCATGGGGAGAAAGATGAAAC
CTGTGTTCCCCTTTTTTTGGTAGTGCCCACATCTGGTGCCCCATTTTTAATAACCACAGGATATTTCTTTAGATTGATATTCTCACAAAG
AAGAAATAGAATATAGGCTGGGCGTGGTGTGTCACACCTGTAATCCCAGCACTTACGGAGGCCGAAGCCAGCGGATCACCAGAGGTCAGG
AGTTCGAGACCAGCCTGACCAACATGATGAAACCCTGTCTCTACTAAAAATACAAAAATTAGCCAGGCATGGTGGCATGCACTTGTAATC
CCAGCTACTCGGGAGGCTGAGACAGGAGAATCGCTTGAACCTGGGAGGCAGAGGTTGCAGTAAGCCAAGATCGCACCATTGCACTACAGC
CTGGGCAACAAGAGGAGCGAAACTCTGTCTCAAAAAAAAAAAAGAGAAAGAATATAAAGTGAATCTGAATCTCCACTCAAGGGGATGGCC
CCAAGGATATTGTAGCTGGTAATTTCTTCATGCCACTAGGTGTCCCCAGTGTTCAACCTCCATGACTGAGATTGGAAGAAGTAGAGTTAA
AAGTTTTTACTACCTTTGAGAAGCCTGCGGGCATGTTCACAGTCGTCCCATGCCAGCCAGGTTCTGAGGCTAACTGCTTGTGCCCCTGCT
GCTTCACATGGCATTGTGGGAGTTGCTGATACTGGGGAAATGATGGCAGATCTGACCAAGTGGTGCTGAGAAAACCACCCTCGGCCTTGC
AGACTCCATAGTTTATCTCAAGGCAGTGCCAGTCGGATTTGGTGCTAAAGGCATAAGGCCAAGTCAGCCTCTGATATTGGCACAAAAGAA
TGGTCTCATGCCAGTAGCATTGAACTGCTGAGCTTGGGAAGGCTTAAGGCTCCCACACACAGACTGAGAATGATGGGGGTCCCTCTGCGT
CTGCTAATTAGACAAACATTCTATATCTAGTGCCAAAAGTGGTCCTAAATCCTTTGGCAAGGGTCCTTTCTGCTCTCATGCTGATTTGGG
GGAGGACTGGGCATCCTGCCTCAGGAGAACTTGAGTCCTGAGGAAAGGGCCCTAGTAACACTTAAGGGCTACCCCTGGCTAACAGATACT
CGGCTGTGGGTGAGAGCAGAAGGTCTTGGACCCCTCGATGTGCAGGTACTTAATTGTGTTTCCAGTGCATTTTCATATACATTATCCCAT
TTAACCTTTATAACAGGTTCACAGAGTGGATATTCCCATTCTGTTGATGAGAAAAAGAGTGGAGAGACTGTGTCCAGTGTCAGCAGGAAG
AAAAAAGATCTGTTGGAGGCCAGTACATGTTGACAGAAACTCTAGACCATATTTTGTCTCCTGTCTTTGGCCAAAGAGAACTAGCTTCAG
TCTGAAAAGGGCAGGGCTAAGTGGTTACAAGGAACTAAAAAGTTCAAGGTAAGACAAATGAGGTAAAAATAAAAAAGAGCACTTAGCTGC
TCTGAGACATTTTAGTCTCCTGACTGGTAAACAGCAGCTGGGGCACCAAGGGGCTCCCAGGAGTTTGTCGAGCTTTTATTGGAGTGAACT
GAAAGGAAAATGGAAGGAATGCTATAAGACTGAAAAGAAGTTAAAGCCCTAGGAAGGAAGCTGATAACACAAGTTACAGACGTATATGTG
ACATTGATTTGGGAGAATGAACCTACAACAAATGACCCAAAAGCACCTAAATAAGAGTGACGAGAGTTTAACAGACATTCATTATGGACT
TCAGAGAAAATGATGCTAAACTGGTCTTAGAATCTTCTTTAATTTTGTTAACTAGGTAAATAATCTGGACATTTTAGTCAAAGCATTAGA
CAGACAGAGAAGTTGGTAACTGACCACTAACTAACAAACTATAAATTCACCCATTGTGGGTTGACCTGGTAAGTTCCCCCAGGGCTGTGT
CCTTGGCCCCTCCTTTGATATTAGTGACAGATGACTTTTTTTATGCCTTACCCATTCCACAAAAGAATTTGAAGCCATTTACACAAGAGA
TAGTACTAGTAAATTAGGAGTGCTGATCAAATTTTTAGATAATAAGAAACCCTTAGGAAGGATGACAATTTAGAATCCAAATTTAGGATC
CAAACAAATACCATTACAAACTATAAAAATGAGCAGAATCTAAATGTAACATTTCAATAAATGCAGATTGATAATAACATCTGTGCAGAG
TTGAGGACTATAGAGTACTGTGCTGTCACTAACAGTATTGTGTGCTACTAAGAGTTTAATGGCTGGGTGTGGTGGCTCACACCTGTAATC
CCAACACTTTGGGAGGCCTAGGTGGGTAAATCAGCTGAGATCAGGAGTTCGAGACCAGCCTGGCCAATGTGGTGAAACCCCGCCTCTACT
AAAAATAAAAAAATTAGCTGGGCATGGTGGCACGTGCCTGTAATCCCAGCTACTCGGGAGGCTGAGGCGGGAGAATCACTTGAACCTGGG
AGACAGAGGTTGCAGTGAGTCGAGATCACACCATTGCACTCCAGCCTGGGCAACAGAGCAAGATTCTGTCTCAAAAAATAAAGTTTATTA
TGCCAGGAGGGCCAGGTGTGGTGCCACACCCATGTAATCCCAGCACTTTAGGAGGCTGAGGAGGGCAGATCACTTAAGCCCAAGAGTTTG
AGACCAGTCTGGGCAATGTGGCAATACCTTGTCTCTTAAAATTTAAAATAAAAAAAAAGTTTATTATGCCAGGAACTGTTAATGTGTCCA
AAAAAACTCCAGTGTGGTTCTAGGATGAGATAATAAAAACAGGTTGTCTAGGGTAGTGTGGAAGGTCCTTTCAGTCTTCCTGTGCCTATC
AGTGATCCTCATTGCCATGTTCCCTTCTGGTGCTCAACCGGAGGCTCCCTGACAGATGAGTCCTCTGCCAGAGGAAGGCTAAGATGTAGA
GGACAAATCGTGTCAAGGAAAAGAAGCTTGAAGGAGCTAAGAATGCTTAGCTTAGAGAAGACAAGAGGAAACAGGACATGGCTTTGGGAA
GTTCAAGGATGGTCCAGTGAAATACATACTATACTTTTGCACCCCAGCTAAGCTGACCCATGATCAGTAAGTAGGAAATAAAAGGCCAAT
TTCTGGCTACTCTTGCCCCCAACCCCATTTCAGTGAACTATGAACCTCTATTAGATATGCAAGGCCGGTGCTAAATGCTGGAGGGCTTTG
GCCCTTTCCCTCAAGGAGCTAGTCTAGTAGGGGGTCAGAAATACAGATGGGCCTGAACATAATGATGGTTTGACTTCCAGTTTTTCAACT
TTAGGATTGTGCAAAAGCTATACACATTCGGTAGAAACAGTACTTCAAGTATCCATACAATCAGTACAGTATTCAATAAATTACATGAGA
CATTCAACACTTTATTATAAAATAGGCTTTGTGTTAGATGAGTTTGCCCAACTGTAAGCTAATGTAAGTGATCTGAGTAGGTTTAAGGTA
GCCTAGGTGTATTAAATGCATTTTTCACTTAACGGTATTTTCAACTTTTGTTGGGTTTATTGGGATGTAGCCCCATTATAAGCTGAAAAG
CATCTGTAGTATAATAAATGTGGGGAGTGCTGTGAGAGAAATAAGTGTACTGGGTTTAGTTCCCACTGCCCAAAAAAGGAACTGGCTAAT
GGTAACCTGGGGGAGGAAGTCGGGTAAGTTGCATGGAGAAGGCAACCCTTGAACACTTGCAAGGAGCTAACAATACCTGCTTCTGGAGTA
TTTAAACGCCAGTGGGTATGCTAAATACTTTTACCTCAGACCACCTACTAACCTTACAAAGTAGTCCACTTTGCTCACCCAGTTTTACAG
ATTGATGAAACTGAAGCAGACAGATATTGTTAACCTATCAAAGGTCACCCTGCAAGTGTGTGATTATAGTCCAAGCAGCTTGTACTTGTT
GCCTATTTGTTTTGCCTTTCCTGTGCATTTGCCAGGCAGATGAGAGTGGGGTAAGACATTGCAGAGAAAAAGTAAGAAAAGGCCGTCATG
AAACAATTTCATTTTCAGACCTTATAAGCACGTTACAAGTACTGATATTTATGCTTAAGTTCACGGGAGTCCTGGCCAGAAATAAAGCTG
GAAGGACAAGTGGGGGGCAGATTGTGAAGGATCCTTCAAGACCTGCTTCCTCTAGAGAATGGGAGACTACCCAAGATAACTAAACAGGGA
AGTGATCAGGTTTTGTGTCTTAGAAAAGTGTTGCAGTGTTGATGCAAATGTGACTAGAAGGGTGACTTGGAACCTGGATTGAAGGGGTGG
GAGATGGGAGAAAGGAATGCAGTCTGGCAGCAGCTACAGCAGTCCAGGTGGGAAAACCCAGAGCCTGAACTAAGGTTGTAACTAGAGGGG
ATAGGGTGGAAGAGCTGGATTAGAGATGTTGACAAGATAAAGTCAGTAGGACTTAAAGACTGACAAGTAAGGATTTTCCAAAAGTGAGAG
CTGTGGAATGAATTGTCTTAAAATGTTGCAGTGAGTTCCTCCTCATCAATCCAAGTGCTCGATCAGAGGCTAGACCTTTAGTTAGCAGTC
ACGGGAAAATTCCCCATTCTCACGGGGATTTAGACTAGGTCTTAACCATACTTTACCAAGATTCCAGTAGCAAAGCACCCAAAAGTAATC
GCAATAAAATTCCAATTTTTGTAGGCCGGGCATAGTGGCTCACACCTGTAATCCCAGCACTTTGGGAGGCCGAGGCAGGCGGACCACGAC
ATCAAGAGTTCAAGAGCAGCCTGGCCAGCATGGTGAAACCCCGTCTCTACTAAAAATACAAAAAAATTAGCTGGGCATGGTGGCGCATGC
CTATAATCCTAGCTACTCAGGCAGCTGAAGCAGGAGAATTGCTTGAACCCGGGAGGCAGAGGTTGCAGTGAGCCAAGATCATGCCACTAC
ACTCCAGCCTGGGCGACAGAGCGACACTCTGCCTCAAAAAAAAAAAAAAACAAAAAAAAAAACAAGTTTTGTGAATTTAAGTTTCCCTAA
TGGATGGTACAGGTCAACATTTGCCATCTAATGACACTTACATTCCAGTTTTTTCCTTTTTTGAGTAACTGGGAAAAGGGTGGCATTACT
GCTGGCTTCCTAAAATTGAAAAGTATACTAGGGTTTTTAAACCTGTGTAGAATACATGATATGGTAGCAAATGTGCTGTAGGAAGAAAAG
CAATGAGGAACTACTGGCCTGACTAGGAGGCCTAGAAGTCCCTCCCAGGCTTGAGTTGTTCTGACTTGGCATGATTACATAGCTGCGGCA
AGTGACGTTTCCTTCAAGCCTTGGTTCCCTCATCTGTAAAATAGGGAACTAATACCTACCTCACAGGATTGTAGTTAGAATTAAGGATGA
CTTCATTAAAGCACCTCTAGTGGTGGAAGATGTCCCATCCTATCCCCCACCCATAGCTGGGAGCTATGTTTGGCTCATTCTTCCTGACTC
ACTGGATTACACTGTGACTCAGTTCAATTTCACACATGCTGCTGCTAAATTAGGGTCTTGGTGAGCCTTTGGGAGGACAGCTCTGAGGAA
TGAATTGTAGCACTGCAGCCCTGCCTGAGGAACATGATAGAAACAGGTGGTAGGCCCAGCTCTTGCCTTCCACCTACTAAGCAGTTTTTC
TGTGGTTAGCTGTGTGACATAAACTATCGGTGTATTAATTTGCTTTCACTAGATTCCCCCCCCCCCAACAACTTAGTCCAAGAACATACC
TGAATTCTTTGCATTTCCTTGCCTTAGTTGCTTTTGTAGGGTGGACAGCAGGACTGCATGAGAATAGCTGTGCTTCTGGACCCTATGGTG
AAAGCTCTAGTGAACTGCAATTAGGCCCAGGGTCCCGGAGGAAGAAGGGGAGAGAAAAAGGGGGGTAGTTTTCCAAAAGATAAGTAGGGG
ACAAAAAAGTCCACGGGGCCTATGAGCGGTGAGACTCCTGCCCTGATTGTGGCAAAGCACCTGGAGATGATAGAACTTCCTAGGGAAAAG
GCTGCATGGAGTCCCCAGGGATGCTGGGCCCTGGTCACCAAGGCTCCCTGGGAAGGTCTCTTGTACCTGGGGCACACAGACCAACACTTC
TGAATTTGCAAGCTTAAGAGCATGTATGAGCAGAACCTGTGCAGACCAAGGCTTAGAGGGCTCACCTCAATGTTTTGCACTGTGTGAGAC
CCCAGGACCTTTTCGTGATTCTGGAGAGGGGAACAAACCATAATAACAACAAACCAGGTAGCAGGATAGAGACTCATTCTCATCTATTTT
GGTTAAAAGAAAATAAATGTATTTCTTCCACACCTGATTTTGTGATTGCAAATTCATAACTAATATCCCTCGTCAGCTCCGCTGACTCAT
CCCTGCCACAGGGAGGTTCACAGCAAGAGCACAGAAACTAGGGCCAGTGCCCGGTTGTGTGACCTTGAGTAAGTTCTTTTTCCCTTGAAC
AGGGAGAGAGACACAATGGATCAGAGTGTCTCTGCCAGTTCTAACTTGGGGATTCTAGTGGGTTGAACCGAACGGTAGTCCGTTTCCAAA
AGAGGAAGCCAAGACCAGAGGGGGAGTGGTTCCTTCAAGTTTGCAGAACCAGTAAGTGGCAGAGCAGGACTCATATCTAGTTAGTGGTTC
AGAGCATGGGCTCCGGAGCTAGACTGCCTGGATTTGAACCCTGGCTTTGCCACTTGCCTGTTGGGTGACTTTGGACAAGCTGCTTAAATT
ATGTCTCCATTTCCTAATCCACAGAACAAGTGTAATACTAGTTATCTGTTTCATGGAGTGATTGTGAGGATTAAATAAAGTTAATATAAC

>In-frame_FDPS_ENST00000368356_chr1_155282186_+_IPO9_ENST00000361565_chr1_201840289_+_9552nt
AGTGTGGGGAGAGCGGGAACTACTCGACCCACAGAGCCGATCGCGGAGCGGATTCTGCTTTTAGGAGTACCCGCCAACAAGCGGGACCGA
GCAGGAATCCGTATCTGGGAACAGGATGCCCCTGTCCCGCTGGTTGAGATCTGTGGGGGTCTTCCTGCTGCCAGCCCCCTACTGGGCACC
CCGGGAGAGGTGGCTGGGTTCCCTACGGCGGCCCTCCCTGGTGCACGGGTACCCAGTCCTGGCCTGGCACAGTGCCCGCTGCTGGTGCCA
AGCGTGGACAGAGGAACCTCGAGCCCTTTGCTCCTCCCTCAGAATGAACGGAGACCAGAATTCAGATGTTTATGCCCAAGAAAAGCAGGA
TTTCGTTCAGCACTTCTCCCAGATCGTTAGGGTGCTGACTGAGGATGAGATGGGGCACCCAGAGATAGGAGATGCTATTGCCCGGCTCAA
GGAGGTCCTGGAGTACAATGCCATTGGAGGCAAGTATAACCGGGGTTTGACGGTGGTAGTAGCATTCCGGGAGCTGGTGGAGCCAAGGAA
ACAGGATGCTGATAGTCTCCAGCGGGCCTGGACTGTGGGCTGGTGTGTGGAACTGTCCCTGATCATGGTGTTCGCTCATCTGGTGCACAC
TCAGCTAGAACCTCTCTTGGAGTTCCTGTGTAGCCTCCCAGGACCTACTGGCAAACCTGCTCTAGAGTTTGTGATGGCTGAGTGGACAAG
CCGACAGCACCTGTTCTATGGACAGTATGAAGGCAAAGTCAGCTCTGTGGCACTCTGTAAGCTGCTCCAGCATGGCATCAATGCAGATGA
CAAACGGCTACAGGATATCCGTGTGAAGGGAGAGGAGATCTACAGCATGGATGAGGGCATCCGCACCCGCTCTAAGTCAGCCAAAAACCC
AGAACGCTGGACAAACATTCCTTTGCTGGTCAAGATCCTAAAGCTGATCATCAACGAGCTCTCCAACGTCATGGAGGCTAATGCCGCTCG
CCAGGCCACTCCTGCAGAGTGGAGTCAAGATGACTCCAATGATATGTGGGAGGACCAGGAGGAGGAAGAGGAGGAGGAGGAGGATGGTTT
AGCTGGCCAACTTTTATCTGACATTCTTGCTACAAGTAAATATGAGGAGGATTACTACGAGGATGATGAGGAAGATGACCCTGATGCCCT
GAAGGATCCTCTCTATCAGATTGATCTGCAGGCATATCTCACAGATTTCCTCTGCCAGTTTGCTCAGCAGCCCTGCTACATAATGTTTTC
AGGCCACCTTAATGACAATGAGAGGCGAGTTCTACAGACCATCGGCATCTAAAAAGGGGAGCCTTTCTACATTTGCTCCTTCTGGGCCAG
CCGCAAACCATTTTGCAGCCCTCACTGGCCTTGAGATGCACTTTCTTCTCAACCTAAAGTGGCATCTTGACCCTTGGCCCTTGGCCTCGG
CAGTGACACTGATGACAATTCAGACCAGGCTCACCGGTGCCGTCACTTAGGAATGCTGGAACAAAGGACATTTCTCAAAGTTCCCCTGAA
GACATGCCATCTCTAGAACCTTTTTTCTCCCCGACTCTACCCCCACCTCTGTTCCTAGAGCCCTCTGCTGGCGAGTCCAGAAACATTATT
GCCCAGAAGGATTATGTGTTTATGGATTATTTTGCCCCGCCTCAGGAGCGCAGGAAGTCACTACCATTTATATTCTAAAACAGACCTATC
TATGTTCATAGGACTTCTGATGTGTTCAGATAGGAATCCTCATGAGAGATCATTATGCTTTGTGCCCTGGACCACTGCTGCTCTGGGTTC
TCAGGAGGAACAGGCAAGAGCAGCTTCATTCTAAGCCTTTCCAGTGACCTCAGCCTTGCTTCTCTTCTACAACACTAAGGCTCCTCTGTC
AGAGGAGGTCGTCTTGTTTTTGCTTCATTGCATGACATAACCCTTCCCCTCAAGCTGTTCCTATATATACATGCACACACAAAATAAGCC
AGACAGATGGCAATTTGATCTTCCTTTTTTAGAAAAAAAAAAAAAAATGGGGAAAAGGGATTTTTTTTAAATCCACCTGACCCAACTATA
TTTAATATGCCTCTCCCACACATTACCACAGAGTCTGATATTCAAAGGTTATCCCCTTTCCCTCAGGAAGCCTCTAAAGTGCTTAAGTTG
TAGCCCTCAAATTTGCAACATGTATTTTTCTAGGACAGTAAAGTAATCTTTACAAATGAATTTAGTTGCATGGTATAAGGTGTCTCAGCA
CCTGTTTGCCTTCTATTCCCTTTAGAAGGTAAGTAAAAGTAATGGGGGAAAGGATTAGGTGGAGCCTGTCTAAACATTCTAGTGTGTCTT
GGCAAACATAGCCTGAAATGATTCTTAAAGAACTGGCATTGTTTAATCAAATATTTTTAAGGGAGATTCCTTAATTGGGAAGTTTAGTCT
GTTTGGGGTTCAAAGAGTAAATGAGGATTAGAAAATCATGGAGAGAGGCTGGGCGCGGTGGCTAACGCCTGTAATCCTAGCACTTTGGGA
GGCTGAGATGGGCGGATCACTTGAGATCAGGAGTTTGAGGCTAGCCTGGCCAACACAGTGAAACCTGCATTTCTACTAAAAATACAAAAA
TTAGCTGGGCATGGTGGTGCATGCCTGTAATCCCAGTTAACTTGAGATGCTGAGGCAGGAGAATCGCTTGAACTTGGGAAGCAGAGGTTG
CAGTGAACCGATATCACACCGTTGCATTCCAAGGCAAGACTCAATCACACACACACACACACACACACACAAATCATGGGGAGAAAGATG
AAACCTGTGTTCCCCTTTTTTTGGTAGTGCCCACATCTGGTGCCCCATTTTTAATAACCACAGGATATTTCTTTAGATTGATATTCTCAC
AAAGAAGAAATAGAATATAGGCTGGGCGTGGTGTGTCACACCTGTAATCCCAGCACTTACGGAGGCCGAAGCCAGCGGATCACCAGAGGT
CAGGAGTTCGAGACCAGCCTGACCAACATGATGAAACCCTGTCTCTACTAAAAATACAAAAATTAGCCAGGCATGGTGGCATGCACTTGT
AATCCCAGCTACTCGGGAGGCTGAGACAGGAGAATCGCTTGAACCTGGGAGGCAGAGGTTGCAGTAAGCCAAGATCGCACCATTGCACTA
CAGCCTGGGCAACAAGAGGAGCGAAACTCTGTCTCAAAAAAAAAAAAGAGAAAGAATATAAAGTGAATCTGAATCTCCACTCAAGGGGAT
GGCCCCAAGGATATTGTAGCTGGTAATTTCTTCATGCCACTAGGTGTCCCCAGTGTTCAACCTCCATGACTGAGATTGGAAGAAGTAGAG
TTAAAAGTTTTTACTACCTTTGAGAAGCCTGCGGGCATGTTCACAGTCGTCCCATGCCAGCCAGGTTCTGAGGCTAACTGCTTGTGCCCC
TGCTGCTTCACATGGCATTGTGGGAGTTGCTGATACTGGGGAAATGATGGCAGATCTGACCAAGTGGTGCTGAGAAAACCACCCTCGGCC
TTGCAGACTCCATAGTTTATCTCAAGGCAGTGCCAGTCGGATTTGGTGCTAAAGGCATAAGGCCAAGTCAGCCTCTGATATTGGCACAAA
AGAATGGTCTCATGCCAGTAGCATTGAACTGCTGAGCTTGGGAAGGCTTAAGGCTCCCACACACAGACTGAGAATGATGGGGGTCCCTCT
GCGTCTGCTAATTAGACAAACATTCTATATCTAGTGCCAAAAGTGGTCCTAAATCCTTTGGCAAGGGTCCTTTCTGCTCTCATGCTGATT
TGGGGGAGGACTGGGCATCCTGCCTCAGGAGAACTTGAGTCCTGAGGAAAGGGCCCTAGTAACACTTAAGGGCTACCCCTGGCTAACAGA
TACTCGGCTGTGGGTGAGAGCAGAAGGTCTTGGACCCCTCGATGTGCAGGTACTTAATTGTGTTTCCAGTGCATTTTCATATACATTATC
CCATTTAACCTTTATAACAGGTTCACAGAGTGGATATTCCCATTCTGTTGATGAGAAAAAGAGTGGAGAGACTGTGTCCAGTGTCAGCAG
GAAGAAAAAAGATCTGTTGGAGGCCAGTACATGTTGACAGAAACTCTAGACCATATTTTGTCTCCTGTCTTTGGCCAAAGAGAACTAGCT
TCAGTCTGAAAAGGGCAGGGCTAAGTGGTTACAAGGAACTAAAAAGTTCAAGGTAAGACAAATGAGGTAAAAATAAAAAAGAGCACTTAG
CTGCTCTGAGACATTTTAGTCTCCTGACTGGTAAACAGCAGCTGGGGCACCAAGGGGCTCCCAGGAGTTTGTCGAGCTTTTATTGGAGTG
AACTGAAAGGAAAATGGAAGGAATGCTATAAGACTGAAAAGAAGTTAAAGCCCTAGGAAGGAAGCTGATAACACAAGTTACAGACGTATA
TGTGACATTGATTTGGGAGAATGAACCTACAACAAATGACCCAAAAGCACCTAAATAAGAGTGACGAGAGTTTAACAGACATTCATTATG
GACTTCAGAGAAAATGATGCTAAACTGGTCTTAGAATCTTCTTTAATTTTGTTAACTAGGTAAATAATCTGGACATTTTAGTCAAAGCAT
TAGACAGACAGAGAAGTTGGTAACTGACCACTAACTAACAAACTATAAATTCACCCATTGTGGGTTGACCTGGTAAGTTCCCCCAGGGCT
GTGTCCTTGGCCCCTCCTTTGATATTAGTGACAGATGACTTTTTTTATGCCTTACCCATTCCACAAAAGAATTTGAAGCCATTTACACAA
GAGATAGTACTAGTAAATTAGGAGTGCTGATCAAATTTTTAGATAATAAGAAACCCTTAGGAAGGATGACAATTTAGAATCCAAATTTAG
GATCCAAACAAATACCATTACAAACTATAAAAATGAGCAGAATCTAAATGTAACATTTCAATAAATGCAGATTGATAATAACATCTGTGC
AGAGTTGAGGACTATAGAGTACTGTGCTGTCACTAACAGTATTGTGTGCTACTAAGAGTTTAATGGCTGGGTGTGGTGGCTCACACCTGT
AATCCCAACACTTTGGGAGGCCTAGGTGGGTAAATCAGCTGAGATCAGGAGTTCGAGACCAGCCTGGCCAATGTGGTGAAACCCCGCCTC
TACTAAAAATAAAAAAATTAGCTGGGCATGGTGGCACGTGCCTGTAATCCCAGCTACTCGGGAGGCTGAGGCGGGAGAATCACTTGAACC
TGGGAGACAGAGGTTGCAGTGAGTCGAGATCACACCATTGCACTCCAGCCTGGGCAACAGAGCAAGATTCTGTCTCAAAAAATAAAGTTT
ATTATGCCAGGAGGGCCAGGTGTGGTGCCACACCCATGTAATCCCAGCACTTTAGGAGGCTGAGGAGGGCAGATCACTTAAGCCCAAGAG
TTTGAGACCAGTCTGGGCAATGTGGCAATACCTTGTCTCTTAAAATTTAAAATAAAAAAAAAGTTTATTATGCCAGGAACTGTTAATGTG
TCCAAAAAAACTCCAGTGTGGTTCTAGGATGAGATAATAAAAACAGGTTGTCTAGGGTAGTGTGGAAGGTCCTTTCAGTCTTCCTGTGCC
TATCAGTGATCCTCATTGCCATGTTCCCTTCTGGTGCTCAACCGGAGGCTCCCTGACAGATGAGTCCTCTGCCAGAGGAAGGCTAAGATG
TAGAGGACAAATCGTGTCAAGGAAAAGAAGCTTGAAGGAGCTAAGAATGCTTAGCTTAGAGAAGACAAGAGGAAACAGGACATGGCTTTG
GGAAGTTCAAGGATGGTCCAGTGAAATACATACTATACTTTTGCACCCCAGCTAAGCTGACCCATGATCAGTAAGTAGGAAATAAAAGGC
CAATTTCTGGCTACTCTTGCCCCCAACCCCATTTCAGTGAACTATGAACCTCTATTAGATATGCAAGGCCGGTGCTAAATGCTGGAGGGC
TTTGGCCCTTTCCCTCAAGGAGCTAGTCTAGTAGGGGGTCAGAAATACAGATGGGCCTGAACATAATGATGGTTTGACTTCCAGTTTTTC
AACTTTAGGATTGTGCAAAAGCTATACACATTCGGTAGAAACAGTACTTCAAGTATCCATACAATCAGTACAGTATTCAATAAATTACAT
GAGACATTCAACACTTTATTATAAAATAGGCTTTGTGTTAGATGAGTTTGCCCAACTGTAAGCTAATGTAAGTGATCTGAGTAGGTTTAA
GGTAGCCTAGGTGTATTAAATGCATTTTTCACTTAACGGTATTTTCAACTTTTGTTGGGTTTATTGGGATGTAGCCCCATTATAAGCTGA
AAAGCATCTGTAGTATAATAAATGTGGGGAGTGCTGTGAGAGAAATAAGTGTACTGGGTTTAGTTCCCACTGCCCAAAAAAGGAACTGGC
TAATGGTAACCTGGGGGAGGAAGTCGGGTAAGTTGCATGGAGAAGGCAACCCTTGAACACTTGCAAGGAGCTAACAATACCTGCTTCTGG
AGTATTTAAACGCCAGTGGGTATGCTAAATACTTTTACCTCAGACCACCTACTAACCTTACAAAGTAGTCCACTTTGCTCACCCAGTTTT
ACAGATTGATGAAACTGAAGCAGACAGATATTGTTAACCTATCAAAGGTCACCCTGCAAGTGTGTGATTATAGTCCAAGCAGCTTGTACT
TGTTGCCTATTTGTTTTGCCTTTCCTGTGCATTTGCCAGGCAGATGAGAGTGGGGTAAGACATTGCAGAGAAAAAGTAAGAAAAGGCCGT
CATGAAACAATTTCATTTTCAGACCTTATAAGCACGTTACAAGTACTGATATTTATGCTTAAGTTCACGGGAGTCCTGGCCAGAAATAAA
GCTGGAAGGACAAGTGGGGGGCAGATTGTGAAGGATCCTTCAAGACCTGCTTCCTCTAGAGAATGGGAGACTACCCAAGATAACTAAACA
GGGAAGTGATCAGGTTTTGTGTCTTAGAAAAGTGTTGCAGTGTTGATGCAAATGTGACTAGAAGGGTGACTTGGAACCTGGATTGAAGGG
GTGGGAGATGGGAGAAAGGAATGCAGTCTGGCAGCAGCTACAGCAGTCCAGGTGGGAAAACCCAGAGCCTGAACTAAGGTTGTAACTAGA
GGGGATAGGGTGGAAGAGCTGGATTAGAGATGTTGACAAGATAAAGTCAGTAGGACTTAAAGACTGACAAGTAAGGATTTTCCAAAAGTG
AGAGCTGTGGAATGAATTGTCTTAAAATGTTGCAGTGAGTTCCTCCTCATCAATCCAAGTGCTCGATCAGAGGCTAGACCTTTAGTTAGC
AGTCACGGGAAAATTCCCCATTCTCACGGGGATTTAGACTAGGTCTTAACCATACTTTACCAAGATTCCAGTAGCAAAGCACCCAAAAGT
AATCGCAATAAAATTCCAATTTTTGTAGGCCGGGCATAGTGGCTCACACCTGTAATCCCAGCACTTTGGGAGGCCGAGGCAGGCGGACCA
CGACATCAAGAGTTCAAGAGCAGCCTGGCCAGCATGGTGAAACCCCGTCTCTACTAAAAATACAAAAAAATTAGCTGGGCATGGTGGCGC
ATGCCTATAATCCTAGCTACTCAGGCAGCTGAAGCAGGAGAATTGCTTGAACCCGGGAGGCAGAGGTTGCAGTGAGCCAAGATCATGCCA
CTACACTCCAGCCTGGGCGACAGAGCGACACTCTGCCTCAAAAAAAAAAAAAAACAAAAAAAAAAACAAGTTTTGTGAATTTAAGTTTCC
CTAATGGATGGTACAGGTCAACATTTGCCATCTAATGACACTTACATTCCAGTTTTTTCCTTTTTTGAGTAACTGGGAAAAGGGTGGCAT
TACTGCTGGCTTCCTAAAATTGAAAAGTATACTAGGGTTTTTAAACCTGTGTAGAATACATGATATGGTAGCAAATGTGCTGTAGGAAGA
AAAGCAATGAGGAACTACTGGCCTGACTAGGAGGCCTAGAAGTCCCTCCCAGGCTTGAGTTGTTCTGACTTGGCATGATTACATAGCTGC
GGCAAGTGACGTTTCCTTCAAGCCTTGGTTCCCTCATCTGTAAAATAGGGAACTAATACCTACCTCACAGGATTGTAGTTAGAATTAAGG
ATGACTTCATTAAAGCACCTCTAGTGGTGGAAGATGTCCCATCCTATCCCCCACCCATAGCTGGGAGCTATGTTTGGCTCATTCTTCCTG
ACTCACTGGATTACACTGTGACTCAGTTCAATTTCACACATGCTGCTGCTAAATTAGGGTCTTGGTGAGCCTTTGGGAGGACAGCTCTGA
GGAATGAATTGTAGCACTGCAGCCCTGCCTGAGGAACATGATAGAAACAGGTGGTAGGCCCAGCTCTTGCCTTCCACCTACTAAGCAGTT
TTTCTGTGGTTAGCTGTGTGACATAAACTATCGGTGTATTAATTTGCTTTCACTAGATTCCCCCCCCCCCAACAACTTAGTCCAAGAACA
TACCTGAATTCTTTGCATTTCCTTGCCTTAGTTGCTTTTGTAGGGTGGACAGCAGGACTGCATGAGAATAGCTGTGCTTCTGGACCCTAT
GGTGAAAGCTCTAGTGAACTGCAATTAGGCCCAGGGTCCCGGAGGAAGAAGGGGAGAGAAAAAGGGGGGTAGTTTTCCAAAAGATAAGTA
GGGGACAAAAAAGTCCACGGGGCCTATGAGCGGTGAGACTCCTGCCCTGATTGTGGCAAAGCACCTGGAGATGATAGAACTTCCTAGGGA
AAAGGCTGCATGGAGTCCCCAGGGATGCTGGGCCCTGGTCACCAAGGCTCCCTGGGAAGGTCTCTTGTACCTGGGGCACACAGACCAACA
CTTCTGAATTTGCAAGCTTAAGAGCATGTATGAGCAGAACCTGTGCAGACCAAGGCTTAGAGGGCTCACCTCAATGTTTTGCACTGTGTG
AGACCCCAGGACCTTTTCGTGATTCTGGAGAGGGGAACAAACCATAATAACAACAAACCAGGTAGCAGGATAGAGACTCATTCTCATCTA
TTTTGGTTAAAAGAAAATAAATGTATTTCTTCCACACCTGATTTTGTGATTGCAAATTCATAACTAATATCCCTCGTCAGCTCCGCTGAC
TCATCCCTGCCACAGGGAGGTTCACAGCAAGAGCACAGAAACTAGGGCCAGTGCCCGGTTGTGTGACCTTGAGTAAGTTCTTTTTCCCTT
GAACAGGGAGAGAGACACAATGGATCAGAGTGTCTCTGCCAGTTCTAACTTGGGGATTCTAGTGGGTTGAACCGAACGGTAGTCCGTTTC
CAAAAGAGGAAGCCAAGACCAGAGGGGGAGTGGTTCCTTCAAGTTTGCAGAACCAGTAAGTGGCAGAGCAGGACTCATATCTAGTTAGTG
GTTCAGAGCATGGGCTCCGGAGCTAGACTGCCTGGATTTGAACCCTGGCTTTGCCACTTGCCTGTTGGGTGACTTTGGACAAGCTGCTTA
AATTATGTCTCCATTTCCTAATCCACAGAACAAGTGTAATACTAGTTATCTGTTTCATGGAGTGATTGTGAGGATTAAATAAAGTTAATA

>In-frame_FDPS_ENST00000356657_chr1_155282186_+_IPO9_ENST00000361565_chr1_201840289_+_9599nt
GAGTACCCGCCAACAAGCGGGACCGAGCAGGAATCCGTATCTGGGAACAGGTGAGAGAGGATGTGTGCTGGGCCTTGGAGGAAGGGGGCC
GAGACCGGGCCTTACTTCTGTAACGATACTGTGAGGCATCGGAAGGCCAGCCTGTTGTGTCCGTTTTGAAGGATGCCCCTGTCCCGCTGG
TTGAGATCTGTGGGGGTCTTCCTGCTGCCAGCCCCCTACTGGGCACCCCGGGAGAGGTGGCTGGGTTCCCTACGGCGGCCCTCCCTGGTG
CACGGGTACCCAGTCCTGGCCTGGCACAGTGCCCGCTGCTGGTGCCAAGCGTGGACAGAGGAACCTCGAGCCCTTTGCTCCTCCCTCAGA
ATGAACGGAGACCAGAATTCAGATGTTTATGCCCAAGAAAAGCAGGATTTCGTTCAGCACTTCTCCCAGATCGTTAGGGTGCTGACTGAG
GATGAGATGGGGCACCCAGAGATAGGAGATGCTATTGCCCGGCTCAAGGAGGTCCTGGAGTACAATGCCATTGGAGGCAAGTATAACCGG
GGTTTGACGGTGGTAGTAGCATTCCGGGAGCTGGTGGAGCCAAGGAAACAGGATGCTGATAGTCTCCAGCGGGCCTGGACTGTGGGCTGG
TGTGTGGAACTGTCCCTGATCATGGTGTTCGCTCATCTGGTGCACACTCAGCTAGAACCTCTCTTGGAGTTCCTGTGTAGCCTCCCAGGA
CCTACTGGCAAACCTGCTCTAGAGTTTGTGATGGCTGAGTGGACAAGCCGACAGCACCTGTTCTATGGACAGTATGAAGGCAAAGTCAGC
TCTGTGGCACTCTGTAAGCTGCTCCAGCATGGCATCAATGCAGATGACAAACGGCTACAGGATATCCGTGTGAAGGGAGAGGAGATCTAC
AGCATGGATGAGGGCATCCGCACCCGCTCTAAGTCAGCCAAAAACCCAGAACGCTGGACAAACATTCCTTTGCTGGTCAAGATCCTAAAG
CTGATCATCAACGAGCTCTCCAACGTCATGGAGGCTAATGCCGCTCGCCAGGCCACTCCTGCAGAGTGGAGTCAAGATGACTCCAATGAT
ATGTGGGAGGACCAGGAGGAGGAAGAGGAGGAGGAGGAGGATGGTTTAGCTGGCCAACTTTTATCTGACATTCTTGCTACAAGTAAATAT
GAGGAGGATTACTACGAGGATGATGAGGAAGATGACCCTGATGCCCTGAAGGATCCTCTCTATCAGATTGATCTGCAGGCATATCTCACA
GATTTCCTCTGCCAGTTTGCTCAGCAGCCCTGCTACATAATGTTTTCAGGCCACCTTAATGACAATGAGAGGCGAGTTCTACAGACCATC
GGCATCTAAAAAGGGGAGCCTTTCTACATTTGCTCCTTCTGGGCCAGCCGCAAACCATTTTGCAGCCCTCACTGGCCTTGAGATGCACTT
TCTTCTCAACCTAAAGTGGCATCTTGACCCTTGGCCCTTGGCCTCGGCAGTGACACTGATGACAATTCAGACCAGGCTCACCGGTGCCGT
CACTTAGGAATGCTGGAACAAAGGACATTTCTCAAAGTTCCCCTGAAGACATGCCATCTCTAGAACCTTTTTTCTCCCCGACTCTACCCC
CACCTCTGTTCCTAGAGCCCTCTGCTGGCGAGTCCAGAAACATTATTGCCCAGAAGGATTATGTGTTTATGGATTATTTTGCCCCGCCTC
AGGAGCGCAGGAAGTCACTACCATTTATATTCTAAAACAGACCTATCTATGTTCATAGGACTTCTGATGTGTTCAGATAGGAATCCTCAT
GAGAGATCATTATGCTTTGTGCCCTGGACCACTGCTGCTCTGGGTTCTCAGGAGGAACAGGCAAGAGCAGCTTCATTCTAAGCCTTTCCA
GTGACCTCAGCCTTGCTTCTCTTCTACAACACTAAGGCTCCTCTGTCAGAGGAGGTCGTCTTGTTTTTGCTTCATTGCATGACATAACCC
TTCCCCTCAAGCTGTTCCTATATATACATGCACACACAAAATAAGCCAGACAGATGGCAATTTGATCTTCCTTTTTTAGAAAAAAAAAAA
AAAATGGGGAAAAGGGATTTTTTTTAAATCCACCTGACCCAACTATATTTAATATGCCTCTCCCACACATTACCACAGAGTCTGATATTC
AAAGGTTATCCCCTTTCCCTCAGGAAGCCTCTAAAGTGCTTAAGTTGTAGCCCTCAAATTTGCAACATGTATTTTTCTAGGACAGTAAAG
TAATCTTTACAAATGAATTTAGTTGCATGGTATAAGGTGTCTCAGCACCTGTTTGCCTTCTATTCCCTTTAGAAGGTAAGTAAAAGTAAT
GGGGGAAAGGATTAGGTGGAGCCTGTCTAAACATTCTAGTGTGTCTTGGCAAACATAGCCTGAAATGATTCTTAAAGAACTGGCATTGTT
TAATCAAATATTTTTAAGGGAGATTCCTTAATTGGGAAGTTTAGTCTGTTTGGGGTTCAAAGAGTAAATGAGGATTAGAAAATCATGGAG
AGAGGCTGGGCGCGGTGGCTAACGCCTGTAATCCTAGCACTTTGGGAGGCTGAGATGGGCGGATCACTTGAGATCAGGAGTTTGAGGCTA
GCCTGGCCAACACAGTGAAACCTGCATTTCTACTAAAAATACAAAAATTAGCTGGGCATGGTGGTGCATGCCTGTAATCCCAGTTAACTT
GAGATGCTGAGGCAGGAGAATCGCTTGAACTTGGGAAGCAGAGGTTGCAGTGAACCGATATCACACCGTTGCATTCCAAGGCAAGACTCA
ATCACACACACACACACACACACACACAAATCATGGGGAGAAAGATGAAACCTGTGTTCCCCTTTTTTTGGTAGTGCCCACATCTGGTGC
CCCATTTTTAATAACCACAGGATATTTCTTTAGATTGATATTCTCACAAAGAAGAAATAGAATATAGGCTGGGCGTGGTGTGTCACACCT
GTAATCCCAGCACTTACGGAGGCCGAAGCCAGCGGATCACCAGAGGTCAGGAGTTCGAGACCAGCCTGACCAACATGATGAAACCCTGTC
TCTACTAAAAATACAAAAATTAGCCAGGCATGGTGGCATGCACTTGTAATCCCAGCTACTCGGGAGGCTGAGACAGGAGAATCGCTTGAA
CCTGGGAGGCAGAGGTTGCAGTAAGCCAAGATCGCACCATTGCACTACAGCCTGGGCAACAAGAGGAGCGAAACTCTGTCTCAAAAAAAA
AAAAGAGAAAGAATATAAAGTGAATCTGAATCTCCACTCAAGGGGATGGCCCCAAGGATATTGTAGCTGGTAATTTCTTCATGCCACTAG
GTGTCCCCAGTGTTCAACCTCCATGACTGAGATTGGAAGAAGTAGAGTTAAAAGTTTTTACTACCTTTGAGAAGCCTGCGGGCATGTTCA
CAGTCGTCCCATGCCAGCCAGGTTCTGAGGCTAACTGCTTGTGCCCCTGCTGCTTCACATGGCATTGTGGGAGTTGCTGATACTGGGGAA
ATGATGGCAGATCTGACCAAGTGGTGCTGAGAAAACCACCCTCGGCCTTGCAGACTCCATAGTTTATCTCAAGGCAGTGCCAGTCGGATT
TGGTGCTAAAGGCATAAGGCCAAGTCAGCCTCTGATATTGGCACAAAAGAATGGTCTCATGCCAGTAGCATTGAACTGCTGAGCTTGGGA
AGGCTTAAGGCTCCCACACACAGACTGAGAATGATGGGGGTCCCTCTGCGTCTGCTAATTAGACAAACATTCTATATCTAGTGCCAAAAG
TGGTCCTAAATCCTTTGGCAAGGGTCCTTTCTGCTCTCATGCTGATTTGGGGGAGGACTGGGCATCCTGCCTCAGGAGAACTTGAGTCCT
GAGGAAAGGGCCCTAGTAACACTTAAGGGCTACCCCTGGCTAACAGATACTCGGCTGTGGGTGAGAGCAGAAGGTCTTGGACCCCTCGAT
GTGCAGGTACTTAATTGTGTTTCCAGTGCATTTTCATATACATTATCCCATTTAACCTTTATAACAGGTTCACAGAGTGGATATTCCCAT
TCTGTTGATGAGAAAAAGAGTGGAGAGACTGTGTCCAGTGTCAGCAGGAAGAAAAAAGATCTGTTGGAGGCCAGTACATGTTGACAGAAA
CTCTAGACCATATTTTGTCTCCTGTCTTTGGCCAAAGAGAACTAGCTTCAGTCTGAAAAGGGCAGGGCTAAGTGGTTACAAGGAACTAAA
AAGTTCAAGGTAAGACAAATGAGGTAAAAATAAAAAAGAGCACTTAGCTGCTCTGAGACATTTTAGTCTCCTGACTGGTAAACAGCAGCT
GGGGCACCAAGGGGCTCCCAGGAGTTTGTCGAGCTTTTATTGGAGTGAACTGAAAGGAAAATGGAAGGAATGCTATAAGACTGAAAAGAA
GTTAAAGCCCTAGGAAGGAAGCTGATAACACAAGTTACAGACGTATATGTGACATTGATTTGGGAGAATGAACCTACAACAAATGACCCA
AAAGCACCTAAATAAGAGTGACGAGAGTTTAACAGACATTCATTATGGACTTCAGAGAAAATGATGCTAAACTGGTCTTAGAATCTTCTT
TAATTTTGTTAACTAGGTAAATAATCTGGACATTTTAGTCAAAGCATTAGACAGACAGAGAAGTTGGTAACTGACCACTAACTAACAAAC
TATAAATTCACCCATTGTGGGTTGACCTGGTAAGTTCCCCCAGGGCTGTGTCCTTGGCCCCTCCTTTGATATTAGTGACAGATGACTTTT
TTTATGCCTTACCCATTCCACAAAAGAATTTGAAGCCATTTACACAAGAGATAGTACTAGTAAATTAGGAGTGCTGATCAAATTTTTAGA
TAATAAGAAACCCTTAGGAAGGATGACAATTTAGAATCCAAATTTAGGATCCAAACAAATACCATTACAAACTATAAAAATGAGCAGAAT
CTAAATGTAACATTTCAATAAATGCAGATTGATAATAACATCTGTGCAGAGTTGAGGACTATAGAGTACTGTGCTGTCACTAACAGTATT
GTGTGCTACTAAGAGTTTAATGGCTGGGTGTGGTGGCTCACACCTGTAATCCCAACACTTTGGGAGGCCTAGGTGGGTAAATCAGCTGAG
ATCAGGAGTTCGAGACCAGCCTGGCCAATGTGGTGAAACCCCGCCTCTACTAAAAATAAAAAAATTAGCTGGGCATGGTGGCACGTGCCT
GTAATCCCAGCTACTCGGGAGGCTGAGGCGGGAGAATCACTTGAACCTGGGAGACAGAGGTTGCAGTGAGTCGAGATCACACCATTGCAC
TCCAGCCTGGGCAACAGAGCAAGATTCTGTCTCAAAAAATAAAGTTTATTATGCCAGGAGGGCCAGGTGTGGTGCCACACCCATGTAATC
CCAGCACTTTAGGAGGCTGAGGAGGGCAGATCACTTAAGCCCAAGAGTTTGAGACCAGTCTGGGCAATGTGGCAATACCTTGTCTCTTAA
AATTTAAAATAAAAAAAAAGTTTATTATGCCAGGAACTGTTAATGTGTCCAAAAAAACTCCAGTGTGGTTCTAGGATGAGATAATAAAAA
CAGGTTGTCTAGGGTAGTGTGGAAGGTCCTTTCAGTCTTCCTGTGCCTATCAGTGATCCTCATTGCCATGTTCCCTTCTGGTGCTCAACC
GGAGGCTCCCTGACAGATGAGTCCTCTGCCAGAGGAAGGCTAAGATGTAGAGGACAAATCGTGTCAAGGAAAAGAAGCTTGAAGGAGCTA
AGAATGCTTAGCTTAGAGAAGACAAGAGGAAACAGGACATGGCTTTGGGAAGTTCAAGGATGGTCCAGTGAAATACATACTATACTTTTG
CACCCCAGCTAAGCTGACCCATGATCAGTAAGTAGGAAATAAAAGGCCAATTTCTGGCTACTCTTGCCCCCAACCCCATTTCAGTGAACT
ATGAACCTCTATTAGATATGCAAGGCCGGTGCTAAATGCTGGAGGGCTTTGGCCCTTTCCCTCAAGGAGCTAGTCTAGTAGGGGGTCAGA
AATACAGATGGGCCTGAACATAATGATGGTTTGACTTCCAGTTTTTCAACTTTAGGATTGTGCAAAAGCTATACACATTCGGTAGAAACA
GTACTTCAAGTATCCATACAATCAGTACAGTATTCAATAAATTACATGAGACATTCAACACTTTATTATAAAATAGGCTTTGTGTTAGAT
GAGTTTGCCCAACTGTAAGCTAATGTAAGTGATCTGAGTAGGTTTAAGGTAGCCTAGGTGTATTAAATGCATTTTTCACTTAACGGTATT
TTCAACTTTTGTTGGGTTTATTGGGATGTAGCCCCATTATAAGCTGAAAAGCATCTGTAGTATAATAAATGTGGGGAGTGCTGTGAGAGA
AATAAGTGTACTGGGTTTAGTTCCCACTGCCCAAAAAAGGAACTGGCTAATGGTAACCTGGGGGAGGAAGTCGGGTAAGTTGCATGGAGA
AGGCAACCCTTGAACACTTGCAAGGAGCTAACAATACCTGCTTCTGGAGTATTTAAACGCCAGTGGGTATGCTAAATACTTTTACCTCAG
ACCACCTACTAACCTTACAAAGTAGTCCACTTTGCTCACCCAGTTTTACAGATTGATGAAACTGAAGCAGACAGATATTGTTAACCTATC
AAAGGTCACCCTGCAAGTGTGTGATTATAGTCCAAGCAGCTTGTACTTGTTGCCTATTTGTTTTGCCTTTCCTGTGCATTTGCCAGGCAG
ATGAGAGTGGGGTAAGACATTGCAGAGAAAAAGTAAGAAAAGGCCGTCATGAAACAATTTCATTTTCAGACCTTATAAGCACGTTACAAG
TACTGATATTTATGCTTAAGTTCACGGGAGTCCTGGCCAGAAATAAAGCTGGAAGGACAAGTGGGGGGCAGATTGTGAAGGATCCTTCAA
GACCTGCTTCCTCTAGAGAATGGGAGACTACCCAAGATAACTAAACAGGGAAGTGATCAGGTTTTGTGTCTTAGAAAAGTGTTGCAGTGT
TGATGCAAATGTGACTAGAAGGGTGACTTGGAACCTGGATTGAAGGGGTGGGAGATGGGAGAAAGGAATGCAGTCTGGCAGCAGCTACAG
CAGTCCAGGTGGGAAAACCCAGAGCCTGAACTAAGGTTGTAACTAGAGGGGATAGGGTGGAAGAGCTGGATTAGAGATGTTGACAAGATA
AAGTCAGTAGGACTTAAAGACTGACAAGTAAGGATTTTCCAAAAGTGAGAGCTGTGGAATGAATTGTCTTAAAATGTTGCAGTGAGTTCC
TCCTCATCAATCCAAGTGCTCGATCAGAGGCTAGACCTTTAGTTAGCAGTCACGGGAAAATTCCCCATTCTCACGGGGATTTAGACTAGG
TCTTAACCATACTTTACCAAGATTCCAGTAGCAAAGCACCCAAAAGTAATCGCAATAAAATTCCAATTTTTGTAGGCCGGGCATAGTGGC
TCACACCTGTAATCCCAGCACTTTGGGAGGCCGAGGCAGGCGGACCACGACATCAAGAGTTCAAGAGCAGCCTGGCCAGCATGGTGAAAC
CCCGTCTCTACTAAAAATACAAAAAAATTAGCTGGGCATGGTGGCGCATGCCTATAATCCTAGCTACTCAGGCAGCTGAAGCAGGAGAAT
TGCTTGAACCCGGGAGGCAGAGGTTGCAGTGAGCCAAGATCATGCCACTACACTCCAGCCTGGGCGACAGAGCGACACTCTGCCTCAAAA
AAAAAAAAAAACAAAAAAAAAAACAAGTTTTGTGAATTTAAGTTTCCCTAATGGATGGTACAGGTCAACATTTGCCATCTAATGACACTT
ACATTCCAGTTTTTTCCTTTTTTGAGTAACTGGGAAAAGGGTGGCATTACTGCTGGCTTCCTAAAATTGAAAAGTATACTAGGGTTTTTA
AACCTGTGTAGAATACATGATATGGTAGCAAATGTGCTGTAGGAAGAAAAGCAATGAGGAACTACTGGCCTGACTAGGAGGCCTAGAAGT
CCCTCCCAGGCTTGAGTTGTTCTGACTTGGCATGATTACATAGCTGCGGCAAGTGACGTTTCCTTCAAGCCTTGGTTCCCTCATCTGTAA
AATAGGGAACTAATACCTACCTCACAGGATTGTAGTTAGAATTAAGGATGACTTCATTAAAGCACCTCTAGTGGTGGAAGATGTCCCATC
CTATCCCCCACCCATAGCTGGGAGCTATGTTTGGCTCATTCTTCCTGACTCACTGGATTACACTGTGACTCAGTTCAATTTCACACATGC
TGCTGCTAAATTAGGGTCTTGGTGAGCCTTTGGGAGGACAGCTCTGAGGAATGAATTGTAGCACTGCAGCCCTGCCTGAGGAACATGATA
GAAACAGGTGGTAGGCCCAGCTCTTGCCTTCCACCTACTAAGCAGTTTTTCTGTGGTTAGCTGTGTGACATAAACTATCGGTGTATTAAT
TTGCTTTCACTAGATTCCCCCCCCCCCAACAACTTAGTCCAAGAACATACCTGAATTCTTTGCATTTCCTTGCCTTAGTTGCTTTTGTAG
GGTGGACAGCAGGACTGCATGAGAATAGCTGTGCTTCTGGACCCTATGGTGAAAGCTCTAGTGAACTGCAATTAGGCCCAGGGTCCCGGA
GGAAGAAGGGGAGAGAAAAAGGGGGGTAGTTTTCCAAAAGATAAGTAGGGGACAAAAAAGTCCACGGGGCCTATGAGCGGTGAGACTCCT
GCCCTGATTGTGGCAAAGCACCTGGAGATGATAGAACTTCCTAGGGAAAAGGCTGCATGGAGTCCCCAGGGATGCTGGGCCCTGGTCACC
AAGGCTCCCTGGGAAGGTCTCTTGTACCTGGGGCACACAGACCAACACTTCTGAATTTGCAAGCTTAAGAGCATGTATGAGCAGAACCTG
TGCAGACCAAGGCTTAGAGGGCTCACCTCAATGTTTTGCACTGTGTGAGACCCCAGGACCTTTTCGTGATTCTGGAGAGGGGAACAAACC
ATAATAACAACAAACCAGGTAGCAGGATAGAGACTCATTCTCATCTATTTTGGTTAAAAGAAAATAAATGTATTTCTTCCACACCTGATT
TTGTGATTGCAAATTCATAACTAATATCCCTCGTCAGCTCCGCTGACTCATCCCTGCCACAGGGAGGTTCACAGCAAGAGCACAGAAACT
AGGGCCAGTGCCCGGTTGTGTGACCTTGAGTAAGTTCTTTTTCCCTTGAACAGGGAGAGAGACACAATGGATCAGAGTGTCTCTGCCAGT
TCTAACTTGGGGATTCTAGTGGGTTGAACCGAACGGTAGTCCGTTTCCAAAAGAGGAAGCCAAGACCAGAGGGGGAGTGGTTCCTTCAAG
TTTGCAGAACCAGTAAGTGGCAGAGCAGGACTCATATCTAGTTAGTGGTTCAGAGCATGGGCTCCGGAGCTAGACTGCCTGGATTTGAAC
CCTGGCTTTGCCACTTGCCTGTTGGGTGACTTTGGACAAGCTGCTTAAATTATGTCTCCATTTCCTAATCCACAGAACAAGTGTAATACT


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FusionGenePPI for FDPS_IPO9


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page

.

check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors
FDPSFGFR1, ATXN1, EIF4ENIF1, EGFR, ADSS, SORD, STAMBP, IDH1, NME1, NME1-NME2, PLS3, TALDO1, MOV10, NXF1, ABCE1, BASP1, CLIC4, DPH2, AIFM3, CTH, G6PD, HNRNPA1, HNRNPA1L2, HNRNPA3, HSPA8, IGF1R, PABPC1, PLAA, SEC31A, XPO1, GARS, SEPHS1, TTC38, NTRK1, CREB3, PPME1, PDSS2, PCYOX1, CLPP, ZMPSTE24, CDC27, TTC19, PDSS1, ALAS1, PSME4, MMAB, ATPAF2, NDUFAF5, GLDC, TRIM25IPO9USP49, MEPCE, RPAP1, PMS1, MYC, APP, NAP1L1, KPNB1, ECT2, CA9, CFTR, NPM1, EGFR, GNPDA1, HMGB3, HEXB, MCTS1, PDCD6IP, SRP14, TNPO3, TUFM, TWF1, USP5, NOL3, PLIN3, TNPO1, FAF2, ADORA3, VTI1B, COMTD1, TNFSF13B, PNKD, PTGER3, HIST1H2BA, UNK, IPO7, CAND1, CANX, COPB1, EPRS, HSP90B1, IDH3A, IPO5, IPO8, KPNA3, KPNA4, POLR3A, POLR3B, PRKCSH, PSMD2, RAB1A, RAN, RCN1, RPN2, SMARCA5, SSR4, XPO1, RPN1, NTRK1, HIST1H2BG, RPGRIP1L, DCTN1, CEP19, RPGRIP1, CENPJ, SORT1, XRCC3, USP37, SNW1, CDC5L, ZNF746, PTPMT1, H2AFX, SIGLECL1, H2AFY2, TMEM206, AKIRIN2, CHRM4, CHRM3, FZD10, HTR2C, KLHDC2, BROX, PTPRE, STOM, MTNR1A, MTNR1B


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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RelatedDrugs for FDPS_IPO9


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status
HgeneFDPSP14324DB00282PamidronateFarnesyl pyrophosphate synthasesmall moleculeapproved
HgeneFDPSP14324DB00399Zoledronic acidFarnesyl pyrophosphate synthasesmall moleculeapproved
HgeneFDPSP14324DB00630Alendronic acidFarnesyl pyrophosphate synthasesmall moleculeapproved
HgeneFDPSP14324DB00710IbandronateFarnesyl pyrophosphate synthasesmall moleculeapproved|investigational
HgeneFDPSP14324DB00884RisedronateFarnesyl pyrophosphate synthasesmall moleculeapproved|investigational

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RelatedDiseases for FDPS_IPO9


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneFDPSC4225262POROKERATOSIS 9, MULTIPLE TYPES1UNIPROT