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Fusion gene ID: 12793 |
FusionGeneSummary for FAM35A_BMPR1A |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: FAM35A_BMPR1A | Fusion gene ID: 12793 | Hgene | Tgene | Gene symbol | FAM35A | BMPR1A | Gene ID | 657 |
| Gene name | bone morphogenetic protein receptor type 1A | ||
| Synonyms | 10q23del|ACVRLK3|ALK3|CD292|SKR5 | ||
| Cytomap | 10q23.2 | ||
| Type of gene | protein-coding | ||
| Description | bone morphogenetic protein receptor type-1AALK-3BMP type-1A receptorBMPR-1Aactivin A receptor, type II-like kinase 3activin receptor-like kinase 3bone morphogenetic protein receptor, type IAserine/threonine-protein kinase receptor R5 | ||
| Modification date | 20180523 | ||
| UniProtAcc | P36894 | ||
| Ensembl transtripts involved in fusion gene | ENST00000298784, ENST00000298786, | ENST00000372037, ENST00000480152, | |
| Fusion gene scores | * DoF score | 5 X 4 X 4=80 | 2 X 2 X 2=8 |
| # samples | 5 | 2 | |
| ** MAII score | log2(5/80*10)=-0.678071905112638 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(2/8*10)=1.32192809488736 | |
| Context | PubMed: FAM35A [Title/Abstract] AND BMPR1A [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | Oncogene involved fusion gene, in-frame and retained their domain. Tumor suppressor gene involved fusion gene, in-frame but not retained their domain. Tumor suppressor gene involved fusion gene, retained protein feature but frameshift. DDR (DNA damage repair) gene involved fusion gene, in-frame but not retained their domain. Kinase involved fusion gene, inframe and retained kinase domain. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Tgene | BMPR1A | GO:0006468 | protein phosphorylation | 12065756 |
| Tgene | BMPR1A | GO:0010862 | positive regulation of pathway-restricted SMAD protein phosphorylation | 9389648|24904118 |
| Tgene | BMPR1A | GO:0030509 | BMP signaling pathway | 9389648|18436533 |
| Tgene | BMPR1A | GO:0060391 | positive regulation of SMAD protein signal transduction | 9389648 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | BRCA | TCGA-A8-A09N-01A | FAM35A | chr10 | 88912636 | + | BMPR1A | chr10 | 88649819 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000298784 | ENST00000372037 | FAM35A | chr10 | 88912636 | + | BMPR1A | chr10 | 88649819 | + |
| 5CDS-3UTR | ENST00000298784 | ENST00000480152 | FAM35A | chr10 | 88912636 | + | BMPR1A | chr10 | 88649819 | + |
| In-frame | ENST00000298786 | ENST00000372037 | FAM35A | chr10 | 88912636 | + | BMPR1A | chr10 | 88649819 | + |
| 5CDS-3UTR | ENST00000298786 | ENST00000480152 | FAM35A | chr10 | 88912636 | + | BMPR1A | chr10 | 88649819 | + |
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FusionProtFeatures for FAM35A_BMPR1A |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| FAM35A | BMPR1A |
| Lectin that binds to various sugars: galactose > mannose= fucose > N-acetylglucosamine > N-acetylgalactosamine(PubMed:10224141). Acts as a chemoattractant, probably involved inthe regulation of cell migration (PubMed:28301481).{ECO:0000269|PubMed:10224141, ECO:0000269|PubMed:28301481}. | On ligand binding, forms a receptor complex consistingof two type II and two type I transmembrane serine/threoninekinases. Type II receptors phosphorylate and activate type Ireceptors which autophosphorylate, then bind and activate SMADtranscriptional regulators. Receptor for BMP2, BMP4, GDF5 andGDF6. Positively regulates chondrocyte differentiation throughGDF5 interaction. Mediates induction of adipogenesis by GDF6.{ECO:0000250|UniProtKB:P36895}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | >BMPR1A | chr10:88912636 | chr10:88649819 | ENST00000372037 | + | 2 | 13 | 204_233 | 22 | 533 | Domain | GS |
| Tgene | >BMPR1A | chr10:88912636 | chr10:88649819 | ENST00000372037 | + | 2 | 13 | 234_525 | 22 | 533 | Domain | Protein kinase |
| Tgene | >BMPR1A | chr10:88912636 | chr10:88649819 | ENST00000372037 | + | 2 | 13 | 240_248 | 22 | 533 | Nucleotide binding | ATP |
| Tgene | >BMPR1A | chr10:88912636 | chr10:88649819 | ENST00000372037 | + | 2 | 13 | 177_532 | 22 | 533 | Topological domain | Cytoplasmic |
| Tgene | >BMPR1A | chr10:88912636 | chr10:88649819 | ENST00000372037 | + | 2 | 13 | 24_152 | 22 | 533 | Topological domain | Extracellular |
| Tgene | >BMPR1A | chr10:88912636 | chr10:88649819 | ENST00000372037 | + | 2 | 13 | 153_176 | 22 | 533 | Transmembrane | Helical |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
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FusionGeneSequence for FAM35A_BMPR1A |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_FAM35A_ENST00000298784_chr10_88912636_+_BMPR1A_ENST00000372037_chr10_88649819_+_1019aa MSGGSQVHIFWGAPIAPLKITVSEDTASLMSVADPWKKIQLLYSQHSLYLKDEKQHKNLENYKVPESIGSPDLSGHFLANCMNRHVHVKD DFVRSVSETQNIESQKIHSSRLSDITSSNMQICGFKSTVPHFTEEEKYQKLLSENKIRDEQPKHQPDICGKNFNTNLFQLGHKCAAVLDL VCSTEKINIGPEVVQRECVPTEYHEIQNQCLGLFSSNAVDKSRSEAAVRKVSDLKISTDTEFLSIITSSQVAFLAQKKDKRRSPVNKGNV NMETEPKASYGEIRIPEENSIQLDGFTEAYESGQNQAYSLELFSPVCPKTENSRIHINSDKGLEEHTGSQELFSSEDELPPNEIRIELCS SGILCSQLNTFHKSAIKRSCTSEDKVGQSEALSRVLQVAKKMKLISNGGDSAVEMDRRNVSEFKSIKKTSLIKNCDSKSQKYNCLVMVLS PCHVKEINIKFGPNSGSKVPLATVTVIDQSETKKKVFLWRTAAFWAFTVFLGDIILLTGQNLDSMLHGTGMKSDSDQKKSENGVTLAPED TLPFLKCYCSGHCPDDAINNTCITNGHCFAIIEEDDQGETTLASGCMKYEGSDFQCKDSPKAQLRRTIECCRTNLCNQYLQPTLPPVVIG PFFDGSIRWLVLLISMAVCIIAMIIFSSCFCYKHYCKSISSRRRYNRDLEQDEAFIPVGESLKDLIDQSQSSGSGSGLPLLVQRTIAKQI QMVRQVGKGRYGEVWMGKWRGEKVAVKVFFTTEEASWFRETEIYQTVLMRHENILGFIAADIKGTGSWTQLYLITDYHENGSLYDFLKCA TLDTRALLKLAYSAACGLCHLHTEIYGTQGKPAIAHRDLKSKNILIKKNGSCCIADLGLAVKFNSDTNEVDVPLNTRVGTKRYMAPEVLD ESLNKNHFQPYIMADIYSFGLIIWEMARRCITGGIVEEYQLPYYNMVPSDPSYEDMREVVCVKRLRPIVSNRWNSDECLRAVLKLMSECW >In-frame_FAM35A_ENST00000298786_chr10_88912636_+_BMPR1A_ENST00000372037_chr10_88649819_+_1019aa MSGGSQVHIFWGAPIAPLKITVSEDTASLMSVADPWKKIQLLYSQHSLYLKDEKQHKNLENYKVPESIGSPDLSGHFLANCMNRHVHVKD DFVRSVSETQNIESQKIHSSRLSDITSSNMQICGFKSTVPHFTEEEKYQKLLSENKIRDEQPKHQPDICGKNFNTNLFQLGHKCAAVLDL VCSTEKINIGPEVVQRECVPTEYHEIQNQCLGLFSSNAVDKSRSEAAVRKVSDLKISTDTEFLSIITSSQVAFLAQKKDKRRSPVNKGNV NMETEPKASYGEIRIPEENSIQLDGFTEAYESGQNQAYSLELFSPVCPKTENSRIHINSDKGLEEHTGSQELFSSEDELPPNEIRIELCS SGILCSQLNTFHKSAIKRSCTSEDKVGQSEALSRVLQVAKKMKLISNGGDSAVEMDRRNVSEFKSIKKTSLIKNCDSKSQKYNCLVMVLS PCHVKEINIKFGPNSGSKVPLATVTVIDQSETKKKVFLWRTAAFWAFTVFLGDIILLTGQNLDSMLHGTGMKSDSDQKKSENGVTLAPED TLPFLKCYCSGHCPDDAINNTCITNGHCFAIIEEDDQGETTLASGCMKYEGSDFQCKDSPKAQLRRTIECCRTNLCNQYLQPTLPPVVIG PFFDGSIRWLVLLISMAVCIIAMIIFSSCFCYKHYCKSISSRRRYNRDLEQDEAFIPVGESLKDLIDQSQSSGSGSGLPLLVQRTIAKQI QMVRQVGKGRYGEVWMGKWRGEKVAVKVFFTTEEASWFRETEIYQTVLMRHENILGFIAADIKGTGSWTQLYLITDYHENGSLYDFLKCA TLDTRALLKLAYSAACGLCHLHTEIYGTQGKPAIAHRDLKSKNILIKKNGSCCIADLGLAVKFNSDTNEVDVPLNTRVGTKRYMAPEVLD ESLNKNHFQPYIMADIYSFGLIIWEMARRCITGGIVEEYQLPYYNMVPSDPSYEDMREVVCVKRLRPIVSNRWNSDECLRAVLKLMSECW |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_FAM35A_ENST00000298784_chr10_88912636_+_BMPR1A_ENST00000372037_chr10_88649819_+_3057nt ATGAGTGGAGGATCTCAAGTCCACATTTTTTGGGGTGCTCCAATTGCTCCACTGAAAATCACAGTATCAGAAGACACAGCTTCTTTAATG TCTGTTGCTGACCCCTGGAAAAAAATTCAGCTTTTATACAGTCAACATTCTTTATATCTGAAGGATGAAAAACAGCACAAAAATCTTGAA AACTATAAAGTCCCAGAATCTATTGGTTCTCCAGATCTTAGTGGTCATTTCTTAGCAAACTGTATGAATAGACATGTTCATGTGAAAGAT GACTTTGTACGTTCTGTTTCTGAAACACAGAATATAGAATCCCAGAAGATTCACTCCTCTAGACTGAGTGATATAACTAGCTCTAATATG CAAATATGTGGATTTAAAAGCACAGTTCCGCATTTCACCGAAGAAGAAAAGTATCAAAAGCTTCTCAGTGAAAATAAAATTAGAGATGAA CAGCCTAAACATCAGCCAGATATATGTGGTAAGAACTTTAACACAAATTTGTTTCAGTTGGGCCATAAATGTGCAGCTGTGTTGGATTTG GTTTGTAGTACTGAAAAAATTAATATAGGGCCTGAAGTGGTACAAAGAGAGTGTGTGCCAACAGAATATCATGAAATACAAAACCAGTGT TTGGGATTATTTTCCTCGAACGCAGTAGATAAGTCAAGGTCTGAAGCAGCAGTTAGGAAGGTCTCAGACCTTAAAATATCAACTGATACA GAATTTCTCAGTATAATTACCTCCAGCCAGGTTGCTTTTTTAGCTCAAAAGAAAGATAAAAGGCGGAGTCCTGTAAATAAAGGGAATGTA AACATGGAGACTGAACCAAAGGCAAGTTACGGGGAGATAAGAATACCTGAAGAGAATTCGATTCAGCTTGATGGTTTTACAGAAGCATAT GAAAGTGGACAAAACCAAGCATATTCCCTTGAACTTTTTAGTCCTGTTTGTCCTAAAACAGAAAATAGCCGCATTCACATAAACTCTGAT AAAGGTCTTGAAGAACATACAGGATCTCAAGAACTTTTCAGTTCTGAAGATGAACTGCCACCAAATGAGATACGTATTGAGTTGTGTAGC TCAGGAATACTGTGTTCCCAACTAAATACCTTCCACAAAAGTGCTATTAAAAGAAGCTGTACCTCTGAAGATAAAGTGGGCCAGTCTGAA GCTCTATCTAGAGTCCTTCAAGTAGCTAAGAAAATGAAGTTGATTTCTAATGGAGGAGATTCTGCTGTAGAAATGGATCGGAGAAATGTG TCTGAATTTAAGAGTATTAAAAAAACATCATTAATAAAAAACTGTGATTCTAAAAGCCAGAAGTATAATTGTTTAGTCATGGTGCTATCT CCATGCCATGTGAAGGAAATAAACATAAAATTCGGACCAAATTCTGGCTCTAAAGTGCCTTTAGCAACAGTTACAGTAATTGATCAATCA GAAACTAAGAAGAAGGTTTTTCTGTGGAGGACTGCAGCATTTTGGGCATTTACAGTGTTTCTTGGAGATATAATTTTACTCACAGGACAG AATCTGGATAGTATGCTTCATGGCACTGGGATGAAATCAGACTCCGACCAGAAAAAGTCAGAAAATGGAGTAACCTTAGCACCAGAGGAT ACCTTGCCTTTTTTAAAGTGCTATTGCTCAGGGCACTGTCCAGATGATGCTATTAATAACACATGCATAACTAATGGACATTGCTTTGCC ATCATAGAAGAAGATGACCAGGGAGAAACCACATTAGCTTCAGGGTGTATGAAATATGAAGGATCTGATTTTCAGTGCAAAGATTCTCCA AAAGCCCAGCTACGCCGGACAATAGAATGTTGTCGGACCAATTTATGTAACCAGTATTTGCAACCCACACTGCCCCCTGTTGTCATAGGT CCGTTTTTTGATGGCAGCATTCGATGGCTGGTTTTGCTCATTTCTATGGCTGTCTGCATAATTGCTATGATCATCTTCTCCAGCTGCTTT TGTTACAAACATTATTGCAAGAGCATCTCAAGCAGACGTCGTTACAATCGTGATTTGGAACAGGATGAAGCATTTATTCCAGTTGGAGAA TCACTAAAAGACCTTATTGACCAGTCACAAAGTTCTGGTAGTGGGTCTGGACTACCTTTATTGGTTCAGCGAACTATTGCCAAACAGATT CAGATGGTCCGGCAAGTTGGTAAAGGCCGATATGGAGAAGTATGGATGGGCAAATGGCGTGGCGAAAAAGTGGCGGTGAAAGTATTCTTT ACCACTGAAGAAGCCAGCTGGTTTCGAGAAACAGAAATCTACCAAACTGTGCTAATGCGCCATGAAAACATACTTGGTTTCATAGCGGCA GACATTAAAGGTACAGGTTCCTGGACTCAGCTCTATTTGATTACTGATTACCATGAAAATGGATCTCTCTATGACTTCCTGAAATGTGCT ACACTGGACACCAGAGCCCTGCTTAAATTGGCTTATTCAGCTGCCTGTGGTCTGTGCCACCTGCACACAGAAATTTATGGCACCCAAGGA AAGCCCGCAATTGCTCATCGAGACCTAAAGAGCAAAAACATCCTCATCAAGAAAAATGGGAGTTGCTGCATTGCTGACCTGGGCCTTGCT GTTAAATTCAACAGTGACACAAATGAAGTTGATGTGCCCTTGAATACCAGGGTGGGCACCAAACGCTACATGGCTCCCGAAGTGCTGGAC GAAAGCCTGAACAAAAACCACTTCCAGCCCTACATCATGGCTGACATCTACAGCTTCGGCCTAATCATTTGGGAGATGGCTCGTCGTTGT ATCACAGGAGGGATCGTGGAAGAATACCAATTGCCATATTACAACATGGTACCGAGTGATCCGTCATACGAAGATATGCGTGAGGTTGTG TGTGTCAAACGTTTGCGGCCAATTGTGTCTAATCGGTGGAACAGTGATGAATGTCTACGAGCAGTTTTGAAGCTAATGTCAGAATGCTGG >In-frame_FAM35A_ENST00000298786_chr10_88912636_+_BMPR1A_ENST00000372037_chr10_88649819_+_3057nt ATGAGTGGAGGATCTCAAGTCCACATTTTTTGGGGTGCTCCAATTGCTCCACTGAAAATCACAGTATCAGAAGACACAGCTTCTTTAATG TCTGTTGCTGACCCCTGGAAAAAAATTCAGCTTTTATACAGTCAACATTCTTTATATCTGAAGGATGAAAAACAGCACAAAAATCTTGAA AACTATAAAGTCCCAGAATCTATTGGTTCTCCAGATCTTAGTGGTCATTTCTTAGCAAACTGTATGAATAGACATGTTCATGTGAAAGAT GACTTTGTACGTTCTGTTTCTGAAACACAGAATATAGAATCCCAGAAGATTCACTCCTCTAGACTGAGTGATATAACTAGCTCTAATATG CAAATATGTGGATTTAAAAGCACAGTTCCGCATTTCACCGAAGAAGAAAAGTATCAAAAGCTTCTCAGTGAAAATAAAATTAGAGATGAA CAGCCTAAACATCAGCCAGATATATGTGGTAAGAACTTTAACACAAATTTGTTTCAGTTGGGCCATAAATGTGCAGCTGTGTTGGATTTG GTTTGTAGTACTGAAAAAATTAATATAGGGCCTGAAGTGGTACAAAGAGAGTGTGTGCCAACAGAATATCATGAAATACAAAACCAGTGT TTGGGATTATTTTCCTCGAACGCAGTAGATAAGTCAAGGTCTGAAGCAGCAGTTAGGAAGGTCTCAGACCTTAAAATATCAACTGATACA GAATTTCTCAGTATAATTACCTCCAGCCAGGTTGCTTTTTTAGCTCAAAAGAAAGATAAAAGGCGGAGTCCTGTAAATAAAGGGAATGTA AACATGGAGACTGAACCAAAGGCAAGTTACGGGGAGATAAGAATACCTGAAGAGAATTCGATTCAGCTTGATGGTTTTACAGAAGCATAT GAAAGTGGACAAAACCAAGCATATTCCCTTGAACTTTTTAGTCCTGTTTGTCCTAAAACAGAAAATAGCCGCATTCACATAAACTCTGAT AAAGGTCTTGAAGAACATACAGGATCTCAAGAACTTTTCAGTTCTGAAGATGAACTGCCACCAAATGAGATACGTATTGAGTTGTGTAGC TCAGGAATACTGTGTTCCCAACTAAATACCTTCCACAAAAGTGCTATTAAAAGAAGCTGTACCTCTGAAGATAAAGTGGGCCAGTCTGAA GCTCTATCTAGAGTCCTTCAAGTAGCTAAGAAAATGAAGTTGATTTCTAATGGAGGAGATTCTGCTGTAGAAATGGATCGGAGAAATGTG TCTGAATTTAAGAGTATTAAAAAAACATCATTAATAAAAAACTGTGATTCTAAAAGCCAGAAGTATAATTGTTTAGTCATGGTGCTATCT CCATGCCATGTGAAGGAAATAAACATAAAATTCGGACCAAATTCTGGCTCTAAAGTGCCTTTAGCAACAGTTACAGTAATTGATCAATCA GAAACTAAGAAGAAGGTTTTTCTGTGGAGGACTGCAGCATTTTGGGCATTTACAGTGTTTCTTGGAGATATAATTTTACTCACAGGACAG AATCTGGATAGTATGCTTCATGGCACTGGGATGAAATCAGACTCCGACCAGAAAAAGTCAGAAAATGGAGTAACCTTAGCACCAGAGGAT ACCTTGCCTTTTTTAAAGTGCTATTGCTCAGGGCACTGTCCAGATGATGCTATTAATAACACATGCATAACTAATGGACATTGCTTTGCC ATCATAGAAGAAGATGACCAGGGAGAAACCACATTAGCTTCAGGGTGTATGAAATATGAAGGATCTGATTTTCAGTGCAAAGATTCTCCA AAAGCCCAGCTACGCCGGACAATAGAATGTTGTCGGACCAATTTATGTAACCAGTATTTGCAACCCACACTGCCCCCTGTTGTCATAGGT CCGTTTTTTGATGGCAGCATTCGATGGCTGGTTTTGCTCATTTCTATGGCTGTCTGCATAATTGCTATGATCATCTTCTCCAGCTGCTTT TGTTACAAACATTATTGCAAGAGCATCTCAAGCAGACGTCGTTACAATCGTGATTTGGAACAGGATGAAGCATTTATTCCAGTTGGAGAA TCACTAAAAGACCTTATTGACCAGTCACAAAGTTCTGGTAGTGGGTCTGGACTACCTTTATTGGTTCAGCGAACTATTGCCAAACAGATT CAGATGGTCCGGCAAGTTGGTAAAGGCCGATATGGAGAAGTATGGATGGGCAAATGGCGTGGCGAAAAAGTGGCGGTGAAAGTATTCTTT ACCACTGAAGAAGCCAGCTGGTTTCGAGAAACAGAAATCTACCAAACTGTGCTAATGCGCCATGAAAACATACTTGGTTTCATAGCGGCA GACATTAAAGGTACAGGTTCCTGGACTCAGCTCTATTTGATTACTGATTACCATGAAAATGGATCTCTCTATGACTTCCTGAAATGTGCT ACACTGGACACCAGAGCCCTGCTTAAATTGGCTTATTCAGCTGCCTGTGGTCTGTGCCACCTGCACACAGAAATTTATGGCACCCAAGGA AAGCCCGCAATTGCTCATCGAGACCTAAAGAGCAAAAACATCCTCATCAAGAAAAATGGGAGTTGCTGCATTGCTGACCTGGGCCTTGCT GTTAAATTCAACAGTGACACAAATGAAGTTGATGTGCCCTTGAATACCAGGGTGGGCACCAAACGCTACATGGCTCCCGAAGTGCTGGAC GAAAGCCTGAACAAAAACCACTTCCAGCCCTACATCATGGCTGACATCTACAGCTTCGGCCTAATCATTTGGGAGATGGCTCGTCGTTGT ATCACAGGAGGGATCGTGGAAGAATACCAATTGCCATATTACAACATGGTACCGAGTGATCCGTCATACGAAGATATGCGTGAGGTTGTG TGTGTCAAACGTTTGCGGCCAATTGTGTCTAATCGGTGGAACAGTGATGAATGTCTACGAGCAGTTTTGAAGCTAATGTCAGAATGCTGG |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_FAM35A_ENST00000298784_chr10_88912636_+_BMPR1A_ENST00000372037_chr10_88649819_+_12290nt ACGGGCGGCCGGATTTGCCCGGAGGCCGCACCCGCCTCCGGCGGGGCTCTCAGTGAAAAATGTACTCTGACCTGAATCCTGAATTTTCCT TGATGGTCAAAAGATTAAGAAATCATGAGTGGAGGATCTCAAGTCCACATTTTTTGGGGTGCTCCAATTGCTCCACTGAAAATCACAGTA TCAGAAGACACAGCTTCTTTAATGTCTGTTGCTGACCCCTGGAAAAAAATTCAGCTTTTATACAGTCAACATTCTTTATATCTGAAGGAT GAAAAACAGCACAAAAATCTTGAAAACTATAAAGTCCCAGAATCTATTGGTTCTCCAGATCTTAGTGGTCATTTCTTAGCAAACTGTATG AATAGACATGTTCATGTGAAAGATGACTTTGTACGTTCTGTTTCTGAAACACAGAATATAGAATCCCAGAAGATTCACTCCTCTAGACTG AGTGATATAACTAGCTCTAATATGCAAATATGTGGATTTAAAAGCACAGTTCCGCATTTCACCGAAGAAGAAAAGTATCAAAAGCTTCTC AGTGAAAATAAAATTAGAGATGAACAGCCTAAACATCAGCCAGATATATGTGGTAAGAACTTTAACACAAATTTGTTTCAGTTGGGCCAT AAATGTGCAGCTGTGTTGGATTTGGTTTGTAGTACTGAAAAAATTAATATAGGGCCTGAAGTGGTACAAAGAGAGTGTGTGCCAACAGAA TATCATGAAATACAAAACCAGTGTTTGGGATTATTTTCCTCGAACGCAGTAGATAAGTCAAGGTCTGAAGCAGCAGTTAGGAAGGTCTCA GACCTTAAAATATCAACTGATACAGAATTTCTCAGTATAATTACCTCCAGCCAGGTTGCTTTTTTAGCTCAAAAGAAAGATAAAAGGCGG AGTCCTGTAAATAAAGGGAATGTAAACATGGAGACTGAACCAAAGGCAAGTTACGGGGAGATAAGAATACCTGAAGAGAATTCGATTCAG CTTGATGGTTTTACAGAAGCATATGAAAGTGGACAAAACCAAGCATATTCCCTTGAACTTTTTAGTCCTGTTTGTCCTAAAACAGAAAAT AGCCGCATTCACATAAACTCTGATAAAGGTCTTGAAGAACATACAGGATCTCAAGAACTTTTCAGTTCTGAAGATGAACTGCCACCAAAT GAGATACGTATTGAGTTGTGTAGCTCAGGAATACTGTGTTCCCAACTAAATACCTTCCACAAAAGTGCTATTAAAAGAAGCTGTACCTCT GAAGATAAAGTGGGCCAGTCTGAAGCTCTATCTAGAGTCCTTCAAGTAGCTAAGAAAATGAAGTTGATTTCTAATGGAGGAGATTCTGCT GTAGAAATGGATCGGAGAAATGTGTCTGAATTTAAGAGTATTAAAAAAACATCATTAATAAAAAACTGTGATTCTAAAAGCCAGAAGTAT AATTGTTTAGTCATGGTGCTATCTCCATGCCATGTGAAGGAAATAAACATAAAATTCGGACCAAATTCTGGCTCTAAAGTGCCTTTAGCA ACAGTTACAGTAATTGATCAATCAGAAACTAAGAAGAAGGTTTTTCTGTGGAGGACTGCAGCATTTTGGGCATTTACAGTGTTTCTTGGA GATATAATTTTACTCACAGGACAGAATCTGGATAGTATGCTTCATGGCACTGGGATGAAATCAGACTCCGACCAGAAAAAGTCAGAAAAT GGAGTAACCTTAGCACCAGAGGATACCTTGCCTTTTTTAAAGTGCTATTGCTCAGGGCACTGTCCAGATGATGCTATTAATAACACATGC ATAACTAATGGACATTGCTTTGCCATCATAGAAGAAGATGACCAGGGAGAAACCACATTAGCTTCAGGGTGTATGAAATATGAAGGATCT GATTTTCAGTGCAAAGATTCTCCAAAAGCCCAGCTACGCCGGACAATAGAATGTTGTCGGACCAATTTATGTAACCAGTATTTGCAACCC ACACTGCCCCCTGTTGTCATAGGTCCGTTTTTTGATGGCAGCATTCGATGGCTGGTTTTGCTCATTTCTATGGCTGTCTGCATAATTGCT ATGATCATCTTCTCCAGCTGCTTTTGTTACAAACATTATTGCAAGAGCATCTCAAGCAGACGTCGTTACAATCGTGATTTGGAACAGGAT GAAGCATTTATTCCAGTTGGAGAATCACTAAAAGACCTTATTGACCAGTCACAAAGTTCTGGTAGTGGGTCTGGACTACCTTTATTGGTT CAGCGAACTATTGCCAAACAGATTCAGATGGTCCGGCAAGTTGGTAAAGGCCGATATGGAGAAGTATGGATGGGCAAATGGCGTGGCGAA AAAGTGGCGGTGAAAGTATTCTTTACCACTGAAGAAGCCAGCTGGTTTCGAGAAACAGAAATCTACCAAACTGTGCTAATGCGCCATGAA AACATACTTGGTTTCATAGCGGCAGACATTAAAGGTACAGGTTCCTGGACTCAGCTCTATTTGATTACTGATTACCATGAAAATGGATCT CTCTATGACTTCCTGAAATGTGCTACACTGGACACCAGAGCCCTGCTTAAATTGGCTTATTCAGCTGCCTGTGGTCTGTGCCACCTGCAC ACAGAAATTTATGGCACCCAAGGAAAGCCCGCAATTGCTCATCGAGACCTAAAGAGCAAAAACATCCTCATCAAGAAAAATGGGAGTTGC TGCATTGCTGACCTGGGCCTTGCTGTTAAATTCAACAGTGACACAAATGAAGTTGATGTGCCCTTGAATACCAGGGTGGGCACCAAACGC TACATGGCTCCCGAAGTGCTGGACGAAAGCCTGAACAAAAACCACTTCCAGCCCTACATCATGGCTGACATCTACAGCTTCGGCCTAATC ATTTGGGAGATGGCTCGTCGTTGTATCACAGGAGGGATCGTGGAAGAATACCAATTGCCATATTACAACATGGTACCGAGTGATCCGTCA TACGAAGATATGCGTGAGGTTGTGTGTGTCAAACGTTTGCGGCCAATTGTGTCTAATCGGTGGAACAGTGATGAATGTCTACGAGCAGTT TTGAAGCTAATGTCAGAATGCTGGGCCCACAATCCAGCCTCCAGACTCACAGCATTGAGAATTAAGAAGACGCTTGCCAAGATGGTTGAA TCCCAAGATGTAAAAATCTGATGGTTAAACCATCGGAGGAGAAACTCTAGACTGCAAGAACTGTTTTTACCCATGGCATGGGTGGAATTA GAGTGGAATAAGGATGTTAACTTGGTTCTCAGACTCTTTCTTCACTACGTGTTCACAGGCTGCTAATATTAAACCTTTCAGTACTCTTAT TAGGATACAAGCTGGGAACTTCTAAACACTTCATTCTTTATATATGGACAGCTTTATTTTAAATGTGGTTTTTGATGCCTTTTTTTAAGT GGGTTTTTATGAACTGCATCAAGACTTCAATCCTGATTAGTGTCTCCAGTCAAGCTCTGGGTACTGAATTGCCTGTTCATAAAACGGTGC TTTCTGTGAAAGCCTTAAGAAGATAAATGAGCGCAGCAGAGATGGAGAAATAGACTTTGCCTTTTACCTGAGACTTTCAGTTCGTTTGTA TTCTACCTTTGTAAAACAGCCTATAGATGATGATGTGTTTGGGATACTGCTTATTTTATGATAGTTTGTCCTGTGTCCTTAGTGATGTGT GTGTGTCTCCATGCACATGCACGCCGGGATTCCTCTGCTGCCATTTGAATTAGAAGAAAATAATTTATATGCATGCACAGGAAGATATTG GTGGCCGGTGGTTTTGTGCTTTAAAAATGCAATATCTGACCAAGATTCGCCAATCTCATACAAGCCATTTACTTTGCAAGTGAGATAGCT TCCCCACCAGCTTTATTTTTTAACATGAAAGCTGATGCCAAGGCCAAAAGAAGTTTAAAGCATCTGTAAATTTGGACTGTTTTCCTTCAA CCACCATTTTTTTTGTGGTTATTATTTTTGTCACGGAAAGCATCCTCTCCAAAGTTGGAGCTTCTATTGCCATGAACCATGCTTACAAAG AAAGCACTTCTTATTGAAGTGAATTCCTGCATTTGATAGCAATGTAAGTGCCTATAACCATGTTCTATATTCTTTATTCTCAGTAACTTT TAAAAGGGAAGTTATTTATATTTTGTGTATAATGTGCTTTATTTGCAAATCACCCACTCCTTTACAACCATACTTTATATATGTACATAC ATTCATACTGTAGAAACCAGCTCATGTGTACCTCATATCCCATCCTTAAGAGAAGAAATGTTATAAAGTAGAACTAAATATAAATTTTCA GAATTAATGCATTCAAAGTAATATATCAAATCCAGGACTTTGTTAACTTCAGGTAAAAACTTCATTAGGGTAATATCATCTCAATTTTTT CAAATGAAAGGATTCTCTAATTAGAAATTTATATGTCAGAGCTGTTATAAATTTATCAACTGTCAAATATGTTCTGGACAGCTAAATCAT TTGAGATTTTTGGTTTTTTGATTTCTATTCCCTAACTTGTGAAGACAATGAAAAATCAGGCAGAAATATTTAGTATCTAGTCAGTATCTG TAGCTACACTGTATAACTGTTCTTCAATAAAATGGTTCATATTTTATAGATGCCTTGTTATCTCAAGAAATCTGATTTACATAAACTTAT ACTTCTTTAATGCTTTTTAAATATTTATTCTGAGCAAACAATTCATGAGTACATCAAGTGAGATAGTTTTATTTGATTATAACATAAAAT AAATGTGATTATATCACATCATCATCAAAAAGGTTTAAATTAAATGGGAGGAAATCAGCATATGTCCACCCATTACCAAAATTTGACTAT CATTTAAGGTTAAAACTTACAAATTTGTCTGCACATCAAATTTCACAAATTTGAAAATTGCCTTAACCATTTTGATTAATAAGTTTCATC TGCCATAATTAAAGTCTGAAGTGTTCATCAAGATAAGTAAATTTGCATATGGATAATACCCAATAACTTGTTTTTTCAGAATTTTTCACC ATATGTATACTGAGAAATACAAATATTTTAATCTGCGTTGCCGTATGATATGATTGCACTTAGAACACCCAATTTACTTAAATCTTGGTT TACTTTTGACTTGATACCATAATCTTTAAAATCATTTGTCATCTTTTTTTTTTTTTTTTTGAGACGGAGTCTCGCTCTGTCGCCCAGGCT GGACTGCGGACTGCAGTGGCGCAATCTCGGCTCACTGCAAGCTCCGCTTCCCGGGTTCACGCCATTCTCCTGCCTCAGCCTCCCGAGTAG CTGGGACTACAGGCGCCCGCCACCGCGCCCGGCTAATTTTTTGTATTTTTAGTAGAGACGGGGTTTCACCTTGTTAGCCAGGATGGTCTC AATCTCCTGACCTCATGATCCACCTGCCTCGGCCTCCCAAAGTTCATTTGTCATCTTAATAAAAATATAAAGACAGGCAAAGTTTATTGG AAATGTTCAAATGGTGTGTGGAAGCAAAAAATTACAGCCAGTATATGAGACCACTATTATGGTTTTTTAAAATTAACTTGGTCTAGTAAA AGTGATATCAAGAGTTAATCTTAGAAACTTGCTCAGTAAAAACATTTTCTAGTATAACATGTTCTTTAAAAAGCAAATGCTGCCGTCTTT GGAATCTTAATCTAAAAATGTGGCCGGGCGCGGTGGCTCACGCCTGTAATCCCAACACTTTGGGAGGCTGAGGCGGGTGGATCACAAGGT CAGGAGTTCAAGACCAGCCTGGCCAACATGGTGAAACCCCATCTCTACTAAAAATAAAAAACTCAGCCAGGCGTGGTGGCGGGTGCCTGT AATCCCAGCTACTCGGGAGGCTGAAGCAGGAGAATTGCTTAAAATCAGAAGGTGGAGGTTGCAGTGAGCTGAGATCGTGTCACTGCACTC CAGCCTGGGCAAAAGAGCGAAACTCCATCTCAAATAAACAAACAAATAAATAACAAAAAACAAAAATGTTGCATTAAACTTAGTTCTTGT CTCTCCTTTCCACTCTTATTCTTAAATCTGAAGCTCATCGACTAAGTGAAATATTTAAAGAATATGATAGGCCAGCAAGAAGAAGTATTA TGTAGTACCATAGTTAGTAAATTCGTAAAACCTTGGAAGCCATTATTTGGTCCCACTTGCAATTTAGTGTTTTTGAAGTGTGTAGCTTCA TTCAGATAGCTCTTTAAATAATTAAAATATAAAAGCAAACAACCCAAACTACCTGACTATAAACAGGAAAAGTTAACCCTCAAAGAGAGT TCTTGTGAATTCTCTTTATGCTGGCAAATAGCTCTAGGATTAAAGGCACATTAGGGTTTCCTTCAGTTTGTTTATTCTAAGCTTTTACTG TGCTTTTTACTGAACAAGTTTCTGATGTATAAAACTTGCATCTGATTTCTTTGGAAATATTTTCACAAAAGTTATTTTAATCAGTATTTT TACATTGCCTTTCCAGTGTCCAGAAGTGTTTCTAAACTTAGAAAGTGACCTATAGTTTTTTAAAATTATGTTTTCCTAGAACGTGCCAAA TTTTGATTTACTCTAACAATCAGTACTTTTCTTCAGATGCTTTGTTCTGTTTAGAACAAAAATGCACTATAGTTTTTAAAGAATCATGCA TCTTTGGGTTGGCCCAGGATCAAATTTGATATTGAATAATTTATTCCAGGGCAGCTTTCATAAACATACTTCATAGATGTTGTTTTGAAA TGTTTCTAAATATCTAAAATCATTTCAACAGCAGAAATGATTTTTATTTTAACAAAAGATTATGATAGCCCTTGTAGTGTTTAAAAGTGG TCATATTTATTACTGACTTTGAGTCAGGTGTTAAAATAGCAGTGCCACAGCTCGTCTCTTGCCTTAGTGTGCTGCTGTGAGAGTCACAGT GGAAACTGCAGGGAGGAGGTGTGTTCCTAAGAACCAAAATCCAGCACAGCATCCTGTGAAGCCACGTGTAATGATGGTCCCATAAGGAAA GTATGTGAATATGGCTCTTGTAAAGGATTAACTATTGTAATTTTAGCTTATGCTCTGTATTCTGTTTTCTATGGAATTATTTAAGCCCTT TTAGTGACCTTTGTCCTGGCCCATTTAAAAACTAAAATGTAGTATATATTGTATAAAATGGAAATATCATTATTGCTTCATTAGGGGAAA CTGTACATAGGCATTGAAAGAAGGGTAAAAGCAAGCAGTTTTATCAGGCAGTTGTAAAACACCAAAAATATAGATTCGTCTTTGACGTGT AACACACTAAATGTATTTTGTACAGCATCTGGTTTAAAAGGTGCCTTAAGAGTTTACCATTACTTGCTTTGTTCTATATACAGATTATGT CCAATGTATCATTTTGAAGTAAATAACCTTATTTTAGTATACTTTAGTGATGTGTTTTGTGATGCTACACTCAGACGGTATTGTGCATCA GAAGTCATCTGTTGAGATTTTTGTAATGATTAAGTTAGTGTATATACATATGTTCCTGAGATGTACACTTCAACTACCAGAAACCCAGTA TGGAGCACAGGTAGGTACACGCTTGCCCTGTGGAGATAGAGAACTTCTAAACCTATCACGGTGCAGGGGTTTTTCCTTTAAAAAACAAGA CAAAACATTGTTTTCTTTTTCCTTTTTTTTTTTTTTTTTTTGAGACGGAGTTTTGCTCTTGTTGCCCAGGCTGGAGTGCAATGGCACGAT CTCAGCTCACTGCAACCTTTGCCTCCTGGGTTCAAGCAATTCTCCTGCCTCAGCCTCCCGAATAGCTGGAACTACAGGTGTTTGCCACCA TGCCTGGCTAATTTTTTGTATTTTTAATAGAGACAGGGTTTCACCATGTTGGCCAGGCTGGTCTCGAACTCCTGACCTCAGGTGGCCCAC TTGCCTTGGCCTCCCAAAGTGCTGAGCTTACAGGCATGAGCCACCATGCCTGGCCAAAACATTGTTTTCTGATTATGGAAATGTACTCAT GGCAGAAAATTTGGGAAACAACAGCAAATAATAAAGCAAATAAAAATCACTCAAAATTCTATTGCCAGACATTATCACTATATACATTTG AGTGTTTCTTTTCAATCTTTTTTTTTGAGAGAGTCTTGCTCTGTCACTCAGGGTGGAGTGCAGTAGCGCGATCTCGGCTCAGTGCAACCT CTGCCCCCTGGGTTCAAGTGATTCTCCTGCCTCAGCCTCCCAAGTAGCCGGGATTACAGGTGTGCACCACCACGCCCGGCTAATTTTTGT ATTTTAGTAGAGATGCGGTTTCACCATGTTGGCCCAGGCTGGTCTCGAACTCCTGACCTCAAGTGATCTGCCTACCTCAGCCTCCCAAAG TGCTGGGATTACAGGAGTGAGCCACTGCACCCGGCCTTATTCTTTTTTATGTTGCATTTTTTGTAATATTAGGATCCTAGTATGCCATTA AATAGCCATTGAGAACTTTTTTTTTAATGACTGCACAATATTTGACTAAGAAGATGGAGTAATTTCTGTGCTCAATCCCCTATTGAATAT TTGGATTATTTTCATTGTTTTGAAAAATAGATATTAAGCATCCTTATACATAAATCTTTATTTTCTTATATTACATTTCTGAAAATGAGA CTAGTGGATATGAACTTTTAAAAGATCCTTTAAGATGGAAAAACTAAGGTTCTTGGAAAACATTGCCATATTGCTACTCACAAAGCTTTT CATTTTCATTCCTGCTAGCAGTTCATGAGCTTAGAGCGATGGGATGCATTTACCTGGCCTTAAGATGCTCCTGCTGCAATGGGAAGTGAA GCCTTGGATAGCTTTCCTCCTCCTGTGCAATACTTTCTTGTCATTTTCCCACCTGCACTGAGTCCCACCGCCAGTCAGGGCTGTTTTCAG GTGTATGTGAATTCATCCCAGCAGTGTGCCTTCTGCTGCCTTTTCCTAGGGAACTGAACATGTTAAATCACAGACGCGATGTGGCACTGA TTATTGTTCCTCAAAAGAAATGCGTGTCTGAAGATAGCCTCTTACAGATTCCTCACGGGAGTCTCTGTTCAGTGTCATTGTAAGTTTCTC AGAATAATCGCAGGCGCTCTGATGCAGCCTGGTAAAGAAGACTCAGTGATTTCTGGGAACTGCAAATGCTTGCCAGCTTTCCTTCTGTCT GTGGAAACACTGAATAAATGTATTCATTTCTCCTTTCCAGCAATCTGTTAGTCTCACTGCTCCATTCCAAGGTTTCTTTAATATTATTAA CAGAGCAGACATTAAGAAACAGAATTGTCTAATCCTTGTTCTTCCAAAATAGGTTTAATCCTTGTAGATAGTTTCAAGCAGACAGTAAGT CAGTTACTAAGTTTTCACTTGGAGAAACATTTGCTGATAGTAGTAGCATATTGACCATTTCTGACATGTCATCCTTATATCAAGTTAGGT GCACGCTCCTACACAGCCTTGGCTCAGCGCTTGGAGCATACAGTCTTGACTGGGTGGACATAAACCGCTGAAAGTGGCCAGCAGTGAGCA GAGGCCACCTACTATCAGCGGCACTGCTGCAGGCATGGAGACTTAAATGTGTGAGTGCTGGTATAAGCAGAAGTGGGAGAGTCACCTCGA TGCTGGGATCCAGATGGCGGCTTATTTCAAGTGCAGTGGCACATACAAAAAATATTTTTGGAAGGGAGCAAGGACTAGGGCTGAAAGGTT CATTCATAATCTTTTTTTCTTTTTTTTTTTAGGTGGAGTCTCGCTCTGTCACCCAGGCTGGAGCGCAATGGGGTGATCCCAGCTCACTGC AACCTCCACCTCCCGGGTTAAAGCAATTCTCCTGCCTCAGCCACCTGAGAAGTTGGGATTACAGGCGTGCACCACCACACTCAGCTAATT TTGTATTTTTAGTAGAGACGGGGTTTACCATGTGGGCCAGGCTGGTCTCGAACTCCCAACCTCAGGTGATCTGCCCACCTTGGCCTTCCA GAGTGCTGGGATTATAGGCGTGAGCCACTGCGCCCAGCCCATAATCTCCTTTTGACATAGGAATTGTTAATTCACATATTCCATCAACCT ATTGCTCCTCTGAATCTTAGCAGCTTCTTGGTCTTTGTTCAAATGAAATCTAAGTCAATTCCATATCTCTCAATGTCGCTACATCCACCT CAGTGCTTATATCCTAATTTTGTCTTTTTTAGAGACAGTCTTGCACTGTCACCCAGGCTAGTGTGCAGTGGCTGTTCACAGGCATAATCA TAACGCACTGTAGCCTCAAACTCCTGATCTCAAGCCATCCTCCCACCTCAGCCTCCTGAGTAGCTGGGACCATGCCACCATGCCTGGCTC ACATTCTAAACATTATGCAGGAAGCTCAAAGTGAAAATCAATATGGAATGTTTATATTGAAAATATTTTTGGCTGGGTGCAGTGGCTAAT GCCTCTAATCCCAGCACTCTGGGAGGCTGAGGCGGGCAGACCACCTGAGGTCAGGAGCAGCCTGGCCAACATATAGTGAAACCCTGTCTC TAAGGTACAAAAATTAGCTGGGTGTGGTGGTACTCGCCTGTAGTCCCAGCTCCTTGGGAAGCTGAGGCAGGAGAATCACTTGAACCCAGG AGGCGGAGGTTGCAGTGAGCTGAGATCGCACCACTGCATTCCAGGCTGGGCAACAGAGCAAGACTCCGTCTCTCAAAAAAAAAAAAAGAA AAAAAAATATATATATATATATACACACACACACACACACATATATATATATATATTCAAGCAATGTGAAGAAAATATTGGGCCCCCTTG TTTTTCTTTAATGGAAGAGCCATTTTTAAAAGCCAGTTTAGAATCCAGATGATGACATCTGTTGCTCTACTGTATGACTGAAATGCAGGT CAGTGTTGAAAAACATAAAAAATTGGAAGTCTCCACTGAAAGACCTACACTGCTGTGGGAGGGATTTTAATCAAGACATTTCAAAAGCAA TTTTTATTACTTGATCCTGTCCTCATACTTGGCTAGGAGTTCAGCTGGAGATAGAATCTAACTCTGAAGATGATACTCCATGATCTTCTA GCATCCCTTGTCACCAGTGAGAAGTCTGATGTGGATCTAATAAGTGACATGTTATACAGGTTAACTTATTTTCAAGAAATAGAATTTTCT TTTTATTATTGATGTTGGAAGTTGAAACTGGCCATATCTAAATATATTCATTCTGTTTCTTAGTACTAATGGGATCTTTTCTTAGACCTG GGAAATTTTCTCCCATTATTTCTTTTGTTTCTTCCCTTTTTTCTTTCTTTTCCTTTTCTCTTTCTAGAACTTTCTAGAACAAATCTCAGG TCCCCTAGATGTTTCTTCCATAATTGTTACTATGCTTCTCATATGTTTCATCCTACCTTCTACTTTTGTCAGCCCATCTGAGTTTATTTC AACAGCCAAATGTTTTATTTTGAAATGATTCCAGGCTTCCATTAAAGTTTCATCAATAGTATAAGGACTGCCATTTACCCTTCACCCAGA TTCATAAACTGCTAACATTGCACAATTGCTTTGTCATTCTGTGTGTGTGTGTACAGGAATCACAGAGACTCATCTTGTAATGTTTGTAAT GTCCATGTATCGTGTATGCACACATTTTTTTCTGACCTATTAGAAGCAAATTACAGAGCTAATACCCCTTTATCCCTAAATACTTCAGGG ATGTTCTATTACTTAACCAATTATGTACAATTATCAGAACCAGGAAAGTTCACATTGATACAATAGCAATGACCAACAATACCATAATCT ATAGACCTTACTGAAGTTTTGCTAATTGTTATTTTGGTGTGGTTGGGTTTTTTGTTTGTTTGAGATAGGGTCTCACTCTGTCACCCAGGC TGGAGTACAGTGGCACAGTCATAGCTCACTTCAACCTCAAACTTTGGGCCTCAAGCGATCCTCCCGCCTCAGCCTCCCAAAGGGCTATGA TTACAGGCATGAGCCACCATGCTGGCCTCATTTCCCCTTTCCTTCTCAAAAGGATTCTGGCTTTCCCTACTGCATTCATCCACGTCCACT ACCCGCTCCAAGAGAGCTGAGTAATTGTCAAGCCAGGTTTGGGGAGCTTTCTTGATGGAGGGGATGGAAGGAGGGTGGTGCTCAGGCTAC AGCAGGGAGAGCTTTTCTGTTTTTGAGCTAAAGACATAACAGGGTGCAGAGGCTGAGAAAAGGAGAGTTCTAAGCAACATGTCACGAGCT >In-frame_FAM35A_ENST00000298786_chr10_88912636_+_BMPR1A_ENST00000372037_chr10_88649819_+_12290nt ACGGGCGGCCGGATTTGCCCGGAGGCCGCACCCGCCTCCGGCGGGGCTCTCAGTGAAAAATGTACTCTGACCTGAATCCTGAATTTTCCT TGATGGTCAAAAGATTAAGAAATCATGAGTGGAGGATCTCAAGTCCACATTTTTTGGGGTGCTCCAATTGCTCCACTGAAAATCACAGTA TCAGAAGACACAGCTTCTTTAATGTCTGTTGCTGACCCCTGGAAAAAAATTCAGCTTTTATACAGTCAACATTCTTTATATCTGAAGGAT GAAAAACAGCACAAAAATCTTGAAAACTATAAAGTCCCAGAATCTATTGGTTCTCCAGATCTTAGTGGTCATTTCTTAGCAAACTGTATG AATAGACATGTTCATGTGAAAGATGACTTTGTACGTTCTGTTTCTGAAACACAGAATATAGAATCCCAGAAGATTCACTCCTCTAGACTG AGTGATATAACTAGCTCTAATATGCAAATATGTGGATTTAAAAGCACAGTTCCGCATTTCACCGAAGAAGAAAAGTATCAAAAGCTTCTC AGTGAAAATAAAATTAGAGATGAACAGCCTAAACATCAGCCAGATATATGTGGTAAGAACTTTAACACAAATTTGTTTCAGTTGGGCCAT AAATGTGCAGCTGTGTTGGATTTGGTTTGTAGTACTGAAAAAATTAATATAGGGCCTGAAGTGGTACAAAGAGAGTGTGTGCCAACAGAA TATCATGAAATACAAAACCAGTGTTTGGGATTATTTTCCTCGAACGCAGTAGATAAGTCAAGGTCTGAAGCAGCAGTTAGGAAGGTCTCA GACCTTAAAATATCAACTGATACAGAATTTCTCAGTATAATTACCTCCAGCCAGGTTGCTTTTTTAGCTCAAAAGAAAGATAAAAGGCGG AGTCCTGTAAATAAAGGGAATGTAAACATGGAGACTGAACCAAAGGCAAGTTACGGGGAGATAAGAATACCTGAAGAGAATTCGATTCAG CTTGATGGTTTTACAGAAGCATATGAAAGTGGACAAAACCAAGCATATTCCCTTGAACTTTTTAGTCCTGTTTGTCCTAAAACAGAAAAT AGCCGCATTCACATAAACTCTGATAAAGGTCTTGAAGAACATACAGGATCTCAAGAACTTTTCAGTTCTGAAGATGAACTGCCACCAAAT GAGATACGTATTGAGTTGTGTAGCTCAGGAATACTGTGTTCCCAACTAAATACCTTCCACAAAAGTGCTATTAAAAGAAGCTGTACCTCT GAAGATAAAGTGGGCCAGTCTGAAGCTCTATCTAGAGTCCTTCAAGTAGCTAAGAAAATGAAGTTGATTTCTAATGGAGGAGATTCTGCT GTAGAAATGGATCGGAGAAATGTGTCTGAATTTAAGAGTATTAAAAAAACATCATTAATAAAAAACTGTGATTCTAAAAGCCAGAAGTAT AATTGTTTAGTCATGGTGCTATCTCCATGCCATGTGAAGGAAATAAACATAAAATTCGGACCAAATTCTGGCTCTAAAGTGCCTTTAGCA ACAGTTACAGTAATTGATCAATCAGAAACTAAGAAGAAGGTTTTTCTGTGGAGGACTGCAGCATTTTGGGCATTTACAGTGTTTCTTGGA GATATAATTTTACTCACAGGACAGAATCTGGATAGTATGCTTCATGGCACTGGGATGAAATCAGACTCCGACCAGAAAAAGTCAGAAAAT GGAGTAACCTTAGCACCAGAGGATACCTTGCCTTTTTTAAAGTGCTATTGCTCAGGGCACTGTCCAGATGATGCTATTAATAACACATGC ATAACTAATGGACATTGCTTTGCCATCATAGAAGAAGATGACCAGGGAGAAACCACATTAGCTTCAGGGTGTATGAAATATGAAGGATCT GATTTTCAGTGCAAAGATTCTCCAAAAGCCCAGCTACGCCGGACAATAGAATGTTGTCGGACCAATTTATGTAACCAGTATTTGCAACCC ACACTGCCCCCTGTTGTCATAGGTCCGTTTTTTGATGGCAGCATTCGATGGCTGGTTTTGCTCATTTCTATGGCTGTCTGCATAATTGCT ATGATCATCTTCTCCAGCTGCTTTTGTTACAAACATTATTGCAAGAGCATCTCAAGCAGACGTCGTTACAATCGTGATTTGGAACAGGAT GAAGCATTTATTCCAGTTGGAGAATCACTAAAAGACCTTATTGACCAGTCACAAAGTTCTGGTAGTGGGTCTGGACTACCTTTATTGGTT CAGCGAACTATTGCCAAACAGATTCAGATGGTCCGGCAAGTTGGTAAAGGCCGATATGGAGAAGTATGGATGGGCAAATGGCGTGGCGAA AAAGTGGCGGTGAAAGTATTCTTTACCACTGAAGAAGCCAGCTGGTTTCGAGAAACAGAAATCTACCAAACTGTGCTAATGCGCCATGAA AACATACTTGGTTTCATAGCGGCAGACATTAAAGGTACAGGTTCCTGGACTCAGCTCTATTTGATTACTGATTACCATGAAAATGGATCT CTCTATGACTTCCTGAAATGTGCTACACTGGACACCAGAGCCCTGCTTAAATTGGCTTATTCAGCTGCCTGTGGTCTGTGCCACCTGCAC ACAGAAATTTATGGCACCCAAGGAAAGCCCGCAATTGCTCATCGAGACCTAAAGAGCAAAAACATCCTCATCAAGAAAAATGGGAGTTGC TGCATTGCTGACCTGGGCCTTGCTGTTAAATTCAACAGTGACACAAATGAAGTTGATGTGCCCTTGAATACCAGGGTGGGCACCAAACGC TACATGGCTCCCGAAGTGCTGGACGAAAGCCTGAACAAAAACCACTTCCAGCCCTACATCATGGCTGACATCTACAGCTTCGGCCTAATC ATTTGGGAGATGGCTCGTCGTTGTATCACAGGAGGGATCGTGGAAGAATACCAATTGCCATATTACAACATGGTACCGAGTGATCCGTCA TACGAAGATATGCGTGAGGTTGTGTGTGTCAAACGTTTGCGGCCAATTGTGTCTAATCGGTGGAACAGTGATGAATGTCTACGAGCAGTT TTGAAGCTAATGTCAGAATGCTGGGCCCACAATCCAGCCTCCAGACTCACAGCATTGAGAATTAAGAAGACGCTTGCCAAGATGGTTGAA TCCCAAGATGTAAAAATCTGATGGTTAAACCATCGGAGGAGAAACTCTAGACTGCAAGAACTGTTTTTACCCATGGCATGGGTGGAATTA GAGTGGAATAAGGATGTTAACTTGGTTCTCAGACTCTTTCTTCACTACGTGTTCACAGGCTGCTAATATTAAACCTTTCAGTACTCTTAT TAGGATACAAGCTGGGAACTTCTAAACACTTCATTCTTTATATATGGACAGCTTTATTTTAAATGTGGTTTTTGATGCCTTTTTTTAAGT GGGTTTTTATGAACTGCATCAAGACTTCAATCCTGATTAGTGTCTCCAGTCAAGCTCTGGGTACTGAATTGCCTGTTCATAAAACGGTGC TTTCTGTGAAAGCCTTAAGAAGATAAATGAGCGCAGCAGAGATGGAGAAATAGACTTTGCCTTTTACCTGAGACTTTCAGTTCGTTTGTA TTCTACCTTTGTAAAACAGCCTATAGATGATGATGTGTTTGGGATACTGCTTATTTTATGATAGTTTGTCCTGTGTCCTTAGTGATGTGT GTGTGTCTCCATGCACATGCACGCCGGGATTCCTCTGCTGCCATTTGAATTAGAAGAAAATAATTTATATGCATGCACAGGAAGATATTG GTGGCCGGTGGTTTTGTGCTTTAAAAATGCAATATCTGACCAAGATTCGCCAATCTCATACAAGCCATTTACTTTGCAAGTGAGATAGCT TCCCCACCAGCTTTATTTTTTAACATGAAAGCTGATGCCAAGGCCAAAAGAAGTTTAAAGCATCTGTAAATTTGGACTGTTTTCCTTCAA CCACCATTTTTTTTGTGGTTATTATTTTTGTCACGGAAAGCATCCTCTCCAAAGTTGGAGCTTCTATTGCCATGAACCATGCTTACAAAG AAAGCACTTCTTATTGAAGTGAATTCCTGCATTTGATAGCAATGTAAGTGCCTATAACCATGTTCTATATTCTTTATTCTCAGTAACTTT TAAAAGGGAAGTTATTTATATTTTGTGTATAATGTGCTTTATTTGCAAATCACCCACTCCTTTACAACCATACTTTATATATGTACATAC ATTCATACTGTAGAAACCAGCTCATGTGTACCTCATATCCCATCCTTAAGAGAAGAAATGTTATAAAGTAGAACTAAATATAAATTTTCA GAATTAATGCATTCAAAGTAATATATCAAATCCAGGACTTTGTTAACTTCAGGTAAAAACTTCATTAGGGTAATATCATCTCAATTTTTT CAAATGAAAGGATTCTCTAATTAGAAATTTATATGTCAGAGCTGTTATAAATTTATCAACTGTCAAATATGTTCTGGACAGCTAAATCAT TTGAGATTTTTGGTTTTTTGATTTCTATTCCCTAACTTGTGAAGACAATGAAAAATCAGGCAGAAATATTTAGTATCTAGTCAGTATCTG TAGCTACACTGTATAACTGTTCTTCAATAAAATGGTTCATATTTTATAGATGCCTTGTTATCTCAAGAAATCTGATTTACATAAACTTAT ACTTCTTTAATGCTTTTTAAATATTTATTCTGAGCAAACAATTCATGAGTACATCAAGTGAGATAGTTTTATTTGATTATAACATAAAAT AAATGTGATTATATCACATCATCATCAAAAAGGTTTAAATTAAATGGGAGGAAATCAGCATATGTCCACCCATTACCAAAATTTGACTAT CATTTAAGGTTAAAACTTACAAATTTGTCTGCACATCAAATTTCACAAATTTGAAAATTGCCTTAACCATTTTGATTAATAAGTTTCATC TGCCATAATTAAAGTCTGAAGTGTTCATCAAGATAAGTAAATTTGCATATGGATAATACCCAATAACTTGTTTTTTCAGAATTTTTCACC ATATGTATACTGAGAAATACAAATATTTTAATCTGCGTTGCCGTATGATATGATTGCACTTAGAACACCCAATTTACTTAAATCTTGGTT TACTTTTGACTTGATACCATAATCTTTAAAATCATTTGTCATCTTTTTTTTTTTTTTTTTGAGACGGAGTCTCGCTCTGTCGCCCAGGCT GGACTGCGGACTGCAGTGGCGCAATCTCGGCTCACTGCAAGCTCCGCTTCCCGGGTTCACGCCATTCTCCTGCCTCAGCCTCCCGAGTAG CTGGGACTACAGGCGCCCGCCACCGCGCCCGGCTAATTTTTTGTATTTTTAGTAGAGACGGGGTTTCACCTTGTTAGCCAGGATGGTCTC AATCTCCTGACCTCATGATCCACCTGCCTCGGCCTCCCAAAGTTCATTTGTCATCTTAATAAAAATATAAAGACAGGCAAAGTTTATTGG AAATGTTCAAATGGTGTGTGGAAGCAAAAAATTACAGCCAGTATATGAGACCACTATTATGGTTTTTTAAAATTAACTTGGTCTAGTAAA AGTGATATCAAGAGTTAATCTTAGAAACTTGCTCAGTAAAAACATTTTCTAGTATAACATGTTCTTTAAAAAGCAAATGCTGCCGTCTTT GGAATCTTAATCTAAAAATGTGGCCGGGCGCGGTGGCTCACGCCTGTAATCCCAACACTTTGGGAGGCTGAGGCGGGTGGATCACAAGGT CAGGAGTTCAAGACCAGCCTGGCCAACATGGTGAAACCCCATCTCTACTAAAAATAAAAAACTCAGCCAGGCGTGGTGGCGGGTGCCTGT AATCCCAGCTACTCGGGAGGCTGAAGCAGGAGAATTGCTTAAAATCAGAAGGTGGAGGTTGCAGTGAGCTGAGATCGTGTCACTGCACTC CAGCCTGGGCAAAAGAGCGAAACTCCATCTCAAATAAACAAACAAATAAATAACAAAAAACAAAAATGTTGCATTAAACTTAGTTCTTGT CTCTCCTTTCCACTCTTATTCTTAAATCTGAAGCTCATCGACTAAGTGAAATATTTAAAGAATATGATAGGCCAGCAAGAAGAAGTATTA TGTAGTACCATAGTTAGTAAATTCGTAAAACCTTGGAAGCCATTATTTGGTCCCACTTGCAATTTAGTGTTTTTGAAGTGTGTAGCTTCA TTCAGATAGCTCTTTAAATAATTAAAATATAAAAGCAAACAACCCAAACTACCTGACTATAAACAGGAAAAGTTAACCCTCAAAGAGAGT TCTTGTGAATTCTCTTTATGCTGGCAAATAGCTCTAGGATTAAAGGCACATTAGGGTTTCCTTCAGTTTGTTTATTCTAAGCTTTTACTG TGCTTTTTACTGAACAAGTTTCTGATGTATAAAACTTGCATCTGATTTCTTTGGAAATATTTTCACAAAAGTTATTTTAATCAGTATTTT TACATTGCCTTTCCAGTGTCCAGAAGTGTTTCTAAACTTAGAAAGTGACCTATAGTTTTTTAAAATTATGTTTTCCTAGAACGTGCCAAA TTTTGATTTACTCTAACAATCAGTACTTTTCTTCAGATGCTTTGTTCTGTTTAGAACAAAAATGCACTATAGTTTTTAAAGAATCATGCA TCTTTGGGTTGGCCCAGGATCAAATTTGATATTGAATAATTTATTCCAGGGCAGCTTTCATAAACATACTTCATAGATGTTGTTTTGAAA TGTTTCTAAATATCTAAAATCATTTCAACAGCAGAAATGATTTTTATTTTAACAAAAGATTATGATAGCCCTTGTAGTGTTTAAAAGTGG TCATATTTATTACTGACTTTGAGTCAGGTGTTAAAATAGCAGTGCCACAGCTCGTCTCTTGCCTTAGTGTGCTGCTGTGAGAGTCACAGT GGAAACTGCAGGGAGGAGGTGTGTTCCTAAGAACCAAAATCCAGCACAGCATCCTGTGAAGCCACGTGTAATGATGGTCCCATAAGGAAA GTATGTGAATATGGCTCTTGTAAAGGATTAACTATTGTAATTTTAGCTTATGCTCTGTATTCTGTTTTCTATGGAATTATTTAAGCCCTT TTAGTGACCTTTGTCCTGGCCCATTTAAAAACTAAAATGTAGTATATATTGTATAAAATGGAAATATCATTATTGCTTCATTAGGGGAAA CTGTACATAGGCATTGAAAGAAGGGTAAAAGCAAGCAGTTTTATCAGGCAGTTGTAAAACACCAAAAATATAGATTCGTCTTTGACGTGT AACACACTAAATGTATTTTGTACAGCATCTGGTTTAAAAGGTGCCTTAAGAGTTTACCATTACTTGCTTTGTTCTATATACAGATTATGT CCAATGTATCATTTTGAAGTAAATAACCTTATTTTAGTATACTTTAGTGATGTGTTTTGTGATGCTACACTCAGACGGTATTGTGCATCA GAAGTCATCTGTTGAGATTTTTGTAATGATTAAGTTAGTGTATATACATATGTTCCTGAGATGTACACTTCAACTACCAGAAACCCAGTA TGGAGCACAGGTAGGTACACGCTTGCCCTGTGGAGATAGAGAACTTCTAAACCTATCACGGTGCAGGGGTTTTTCCTTTAAAAAACAAGA CAAAACATTGTTTTCTTTTTCCTTTTTTTTTTTTTTTTTTTGAGACGGAGTTTTGCTCTTGTTGCCCAGGCTGGAGTGCAATGGCACGAT CTCAGCTCACTGCAACCTTTGCCTCCTGGGTTCAAGCAATTCTCCTGCCTCAGCCTCCCGAATAGCTGGAACTACAGGTGTTTGCCACCA TGCCTGGCTAATTTTTTGTATTTTTAATAGAGACAGGGTTTCACCATGTTGGCCAGGCTGGTCTCGAACTCCTGACCTCAGGTGGCCCAC TTGCCTTGGCCTCCCAAAGTGCTGAGCTTACAGGCATGAGCCACCATGCCTGGCCAAAACATTGTTTTCTGATTATGGAAATGTACTCAT GGCAGAAAATTTGGGAAACAACAGCAAATAATAAAGCAAATAAAAATCACTCAAAATTCTATTGCCAGACATTATCACTATATACATTTG AGTGTTTCTTTTCAATCTTTTTTTTTGAGAGAGTCTTGCTCTGTCACTCAGGGTGGAGTGCAGTAGCGCGATCTCGGCTCAGTGCAACCT CTGCCCCCTGGGTTCAAGTGATTCTCCTGCCTCAGCCTCCCAAGTAGCCGGGATTACAGGTGTGCACCACCACGCCCGGCTAATTTTTGT ATTTTAGTAGAGATGCGGTTTCACCATGTTGGCCCAGGCTGGTCTCGAACTCCTGACCTCAAGTGATCTGCCTACCTCAGCCTCCCAAAG TGCTGGGATTACAGGAGTGAGCCACTGCACCCGGCCTTATTCTTTTTTATGTTGCATTTTTTGTAATATTAGGATCCTAGTATGCCATTA AATAGCCATTGAGAACTTTTTTTTTAATGACTGCACAATATTTGACTAAGAAGATGGAGTAATTTCTGTGCTCAATCCCCTATTGAATAT TTGGATTATTTTCATTGTTTTGAAAAATAGATATTAAGCATCCTTATACATAAATCTTTATTTTCTTATATTACATTTCTGAAAATGAGA CTAGTGGATATGAACTTTTAAAAGATCCTTTAAGATGGAAAAACTAAGGTTCTTGGAAAACATTGCCATATTGCTACTCACAAAGCTTTT CATTTTCATTCCTGCTAGCAGTTCATGAGCTTAGAGCGATGGGATGCATTTACCTGGCCTTAAGATGCTCCTGCTGCAATGGGAAGTGAA GCCTTGGATAGCTTTCCTCCTCCTGTGCAATACTTTCTTGTCATTTTCCCACCTGCACTGAGTCCCACCGCCAGTCAGGGCTGTTTTCAG GTGTATGTGAATTCATCCCAGCAGTGTGCCTTCTGCTGCCTTTTCCTAGGGAACTGAACATGTTAAATCACAGACGCGATGTGGCACTGA TTATTGTTCCTCAAAAGAAATGCGTGTCTGAAGATAGCCTCTTACAGATTCCTCACGGGAGTCTCTGTTCAGTGTCATTGTAAGTTTCTC AGAATAATCGCAGGCGCTCTGATGCAGCCTGGTAAAGAAGACTCAGTGATTTCTGGGAACTGCAAATGCTTGCCAGCTTTCCTTCTGTCT GTGGAAACACTGAATAAATGTATTCATTTCTCCTTTCCAGCAATCTGTTAGTCTCACTGCTCCATTCCAAGGTTTCTTTAATATTATTAA CAGAGCAGACATTAAGAAACAGAATTGTCTAATCCTTGTTCTTCCAAAATAGGTTTAATCCTTGTAGATAGTTTCAAGCAGACAGTAAGT CAGTTACTAAGTTTTCACTTGGAGAAACATTTGCTGATAGTAGTAGCATATTGACCATTTCTGACATGTCATCCTTATATCAAGTTAGGT GCACGCTCCTACACAGCCTTGGCTCAGCGCTTGGAGCATACAGTCTTGACTGGGTGGACATAAACCGCTGAAAGTGGCCAGCAGTGAGCA GAGGCCACCTACTATCAGCGGCACTGCTGCAGGCATGGAGACTTAAATGTGTGAGTGCTGGTATAAGCAGAAGTGGGAGAGTCACCTCGA TGCTGGGATCCAGATGGCGGCTTATTTCAAGTGCAGTGGCACATACAAAAAATATTTTTGGAAGGGAGCAAGGACTAGGGCTGAAAGGTT CATTCATAATCTTTTTTTCTTTTTTTTTTTAGGTGGAGTCTCGCTCTGTCACCCAGGCTGGAGCGCAATGGGGTGATCCCAGCTCACTGC AACCTCCACCTCCCGGGTTAAAGCAATTCTCCTGCCTCAGCCACCTGAGAAGTTGGGATTACAGGCGTGCACCACCACACTCAGCTAATT TTGTATTTTTAGTAGAGACGGGGTTTACCATGTGGGCCAGGCTGGTCTCGAACTCCCAACCTCAGGTGATCTGCCCACCTTGGCCTTCCA GAGTGCTGGGATTATAGGCGTGAGCCACTGCGCCCAGCCCATAATCTCCTTTTGACATAGGAATTGTTAATTCACATATTCCATCAACCT ATTGCTCCTCTGAATCTTAGCAGCTTCTTGGTCTTTGTTCAAATGAAATCTAAGTCAATTCCATATCTCTCAATGTCGCTACATCCACCT CAGTGCTTATATCCTAATTTTGTCTTTTTTAGAGACAGTCTTGCACTGTCACCCAGGCTAGTGTGCAGTGGCTGTTCACAGGCATAATCA TAACGCACTGTAGCCTCAAACTCCTGATCTCAAGCCATCCTCCCACCTCAGCCTCCTGAGTAGCTGGGACCATGCCACCATGCCTGGCTC ACATTCTAAACATTATGCAGGAAGCTCAAAGTGAAAATCAATATGGAATGTTTATATTGAAAATATTTTTGGCTGGGTGCAGTGGCTAAT GCCTCTAATCCCAGCACTCTGGGAGGCTGAGGCGGGCAGACCACCTGAGGTCAGGAGCAGCCTGGCCAACATATAGTGAAACCCTGTCTC TAAGGTACAAAAATTAGCTGGGTGTGGTGGTACTCGCCTGTAGTCCCAGCTCCTTGGGAAGCTGAGGCAGGAGAATCACTTGAACCCAGG AGGCGGAGGTTGCAGTGAGCTGAGATCGCACCACTGCATTCCAGGCTGGGCAACAGAGCAAGACTCCGTCTCTCAAAAAAAAAAAAAGAA AAAAAAATATATATATATATATACACACACACACACACACATATATATATATATATTCAAGCAATGTGAAGAAAATATTGGGCCCCCTTG TTTTTCTTTAATGGAAGAGCCATTTTTAAAAGCCAGTTTAGAATCCAGATGATGACATCTGTTGCTCTACTGTATGACTGAAATGCAGGT CAGTGTTGAAAAACATAAAAAATTGGAAGTCTCCACTGAAAGACCTACACTGCTGTGGGAGGGATTTTAATCAAGACATTTCAAAAGCAA TTTTTATTACTTGATCCTGTCCTCATACTTGGCTAGGAGTTCAGCTGGAGATAGAATCTAACTCTGAAGATGATACTCCATGATCTTCTA GCATCCCTTGTCACCAGTGAGAAGTCTGATGTGGATCTAATAAGTGACATGTTATACAGGTTAACTTATTTTCAAGAAATAGAATTTTCT TTTTATTATTGATGTTGGAAGTTGAAACTGGCCATATCTAAATATATTCATTCTGTTTCTTAGTACTAATGGGATCTTTTCTTAGACCTG GGAAATTTTCTCCCATTATTTCTTTTGTTTCTTCCCTTTTTTCTTTCTTTTCCTTTTCTCTTTCTAGAACTTTCTAGAACAAATCTCAGG TCCCCTAGATGTTTCTTCCATAATTGTTACTATGCTTCTCATATGTTTCATCCTACCTTCTACTTTTGTCAGCCCATCTGAGTTTATTTC AACAGCCAAATGTTTTATTTTGAAATGATTCCAGGCTTCCATTAAAGTTTCATCAATAGTATAAGGACTGCCATTTACCCTTCACCCAGA TTCATAAACTGCTAACATTGCACAATTGCTTTGTCATTCTGTGTGTGTGTGTACAGGAATCACAGAGACTCATCTTGTAATGTTTGTAAT GTCCATGTATCGTGTATGCACACATTTTTTTCTGACCTATTAGAAGCAAATTACAGAGCTAATACCCCTTTATCCCTAAATACTTCAGGG ATGTTCTATTACTTAACCAATTATGTACAATTATCAGAACCAGGAAAGTTCACATTGATACAATAGCAATGACCAACAATACCATAATCT ATAGACCTTACTGAAGTTTTGCTAATTGTTATTTTGGTGTGGTTGGGTTTTTTGTTTGTTTGAGATAGGGTCTCACTCTGTCACCCAGGC TGGAGTACAGTGGCACAGTCATAGCTCACTTCAACCTCAAACTTTGGGCCTCAAGCGATCCTCCCGCCTCAGCCTCCCAAAGGGCTATGA TTACAGGCATGAGCCACCATGCTGGCCTCATTTCCCCTTTCCTTCTCAAAAGGATTCTGGCTTTCCCTACTGCATTCATCCACGTCCACT ACCCGCTCCAAGAGAGCTGAGTAATTGTCAAGCCAGGTTTGGGGAGCTTTCTTGATGGAGGGGATGGAAGGAGGGTGGTGCTCAGGCTAC AGCAGGGAGAGCTTTTCTGTTTTTGAGCTAAAGACATAACAGGGTGCAGAGGCTGAGAAAAGGAGAGTTCTAAGCAACATGTCACGAGCT |
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FusionGenePPI for FAM35A_BMPR1A |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| FAM35A | HNRNPA1, DEFA5, TRIM25 | BMPR1A | SF3B4, SMAD7, BMP2, BMPR2, FKBP1B, GDF5, GDF6, BMP7, BMP4, BMP6, FKBP1A, ZMYND11, BMPR1B, BMPR1A, RUNX2, TSC22D1, NEDD4L, NEDD4, IGSF1, FST, SMURF1, MYC, BAMBI, SMAD6, SMAD1, HSP90AA1, PEG10, CAV1, ACVR1, USP15, CLDND1, SNX11, TGFBR2, TSPAN17, GINM1, PTGER3, HEPACAM2, OTUB1, GPR114, MRAP2, LRRIQ1, MANSC1, IL17RB, C16orf58, IFNGR1, FAM171B, HAVCR2, SLC20A1, CD83, FSHR, TLR2, LITAF, TMEM52B, TNFRSF10A, ARRDC3, MAS1, C14orf37, TPCN2, IL1R1, PDCD1, IL4R, PDGFRB, TRIM25 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for FAM35A_BMPR1A |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
| Tgene | BMPR1A | P36894 | DB11639 | Dibotermin alfa | Bone morphogenetic protein receptor type-1A | biotech | approved|investigational |
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RelatedDiseases for FAM35A_BMPR1A |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Tgene | BMPR1A | C0345893 | Juvenile polyposis syndrome | 5 | CTD_human;ORPHANET;UNIPROT |
| Tgene | BMPR1A | C0015393 | Eye Abnormalities | 1 | CTD_human |
| Tgene | BMPR1A | C0376634 | Craniofacial Abnormalities | 1 | CTD_human |
| Tgene | BMPR1A | C1720887 | Female Urogenital Diseases | 1 | CTD_human |
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