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Center for Computational Systems Medicine
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FusionGeneSummary

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FusionProtFeature

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FusionGeneSequence

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FusionGenePPI

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RelatedDrugs

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RelatedDiseases

Fusion gene ID: 12451

FusionGeneSummary for FAM102A_PTGES2

check button Fusion gene summary
Fusion gene informationFusion gene name: FAM102A_PTGES2
Fusion gene ID: 12451
HgeneTgene
Gene symbol

FAM102A

PTGES2

Gene ID

399665

80142

Gene namefamily with sequence similarity 102 member Aprostaglandin E synthase 2
SynonymsC9orf132|EEIG1|SYM-3A|bA203J24.7C9orf15|GBF-1|GBF1|PGES2|mPGES-2
Cytomap

9q34.11

9q34.11

Type of geneprotein-codingprotein-coding
Descriptionprotein FAM102AC230093N12Rikearly estrogen-induced gene 1 proteinsym-3 homolog Aprostaglandin E synthase 2GATE-binding factor 1gamma-interferon-activated transcriptional element-binding factor 1mPGE synthase-2membrane-associated prostaglandin E synthase 2microsomal prostaglandin E synthase-2prostaglandin-H(2) E-isomerase
Modification date2018051920180519
UniProtAcc

Q5T9C2

Q9H7Z7

Ensembl transtripts involved in fusion geneENST00000373095, ENST00000373084, 
ENST00000300434, 		ENST00000338961, 
ENST00000277462, ENST00000483625, 
Fusion gene scores* DoF score7 X 4 X 7=1963 X 2 X 4=24
# samples 84
** MAII scorelog2(8/196*10)=-1.29278174922785
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(4/24*10)=0.736965594166206
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: FAM102A [Title/Abstract] AND PTGES2 [Title/Abstract] AND fusion [Title/Abstract]

Functional or gene categories assigned by FusionGDB annotation
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check button Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
Data typeSourceCancer typeSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
TCGALDGBMTCGA-28-5204-01AFAM102Achr9

130742271

-PTGES2chr9

130887720

-
TCGARVLUADTCGA-69-A59K-01AFAM102Achr9

130715854

-PTGES2chr9

130887720

-
* LD: Li Ding group's fusion gene list
  RV: Roel Verhaak group's fusion gene list
  ChiTaRs fusion database

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000373095ENST00000338961FAM102Achr9

130742271

-PTGES2chr9

130887720

-
5CDS-5UTRENST00000373095ENST00000277462FAM102Achr9

130742271

-PTGES2chr9

130887720

-
5CDS-5UTRENST00000373095ENST00000483625FAM102Achr9

130742271

-PTGES2chr9

130887720

-
intron-3CDSENST00000373084ENST00000338961FAM102Achr9

130742271

-PTGES2chr9

130887720

-
intron-5UTRENST00000373084ENST00000277462FAM102Achr9

130742271

-PTGES2chr9

130887720

-
intron-5UTRENST00000373084ENST00000483625FAM102Achr9

130742271

-PTGES2chr9

130887720

-
intron-3CDSENST00000300434ENST00000338961FAM102Achr9

130742271

-PTGES2chr9

130887720

-
intron-5UTRENST00000300434ENST00000277462FAM102Achr9

130742271

-PTGES2chr9

130887720

-
intron-5UTRENST00000300434ENST00000483625FAM102Achr9

130742271

-PTGES2chr9

130887720

-
In-frameENST00000373095ENST00000338961FAM102Achr9

130715854

-PTGES2chr9

130887720

-
5CDS-5UTRENST00000373095ENST00000277462FAM102Achr9

130715854

-PTGES2chr9

130887720

-
5CDS-5UTRENST00000373095ENST00000483625FAM102Achr9

130715854

-PTGES2chr9

130887720

-
intron-3CDSENST00000373084ENST00000338961FAM102Achr9

130715854

-PTGES2chr9

130887720

-
intron-5UTRENST00000373084ENST00000277462FAM102Achr9

130715854

-PTGES2chr9

130887720

-
intron-5UTRENST00000373084ENST00000483625FAM102Achr9

130715854

-PTGES2chr9

130887720

-
intron-3CDSENST00000300434ENST00000338961FAM102Achr9

130715854

-PTGES2chr9

130887720

-
intron-5UTRENST00000300434ENST00000277462FAM102Achr9

130715854

-PTGES2chr9

130887720

-
intron-5UTRENST00000300434ENST00000483625FAM102Achr9

130715854

-PTGES2chr9

130887720

-

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FusionProtFeatures for FAM102A_PTGES2


check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
FAM102A

Q5T9C2

PTGES2

Q9H7Z7

May play a role in estrogen action.{ECO:0000269|PubMed:14605097}. Isomerase that catalyzes the conversion of PGH2 into themore stable prostaglandin E2 (PGE2). {ECO:0000269|PubMed:12804604,ECO:0000269|PubMed:18198127}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

.

* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgenePTGES2chr9:130715854chr9:130887720ENST00000338961-07263_37793378DomainNote=GST C-terminal
TgenePTGES2chr9:130715854chr9:130887720ENST00000338961-0790_19393378DomainGlutaredoxin
TgenePTGES2chr9:130742271chr9:130887720ENST00000338961-07263_37793378DomainNote=GST C-terminal
TgenePTGES2chr9:130742271chr9:130887720ENST00000338961-0790_19393378DomainGlutaredoxin
TgenePTGES2chr9:130715854chr9:130887720ENST00000338961-07164_16593378RegionGlutathione binding
TgenePTGES2chr9:130742271chr9:130887720ENST00000338961-07164_16593378RegionGlutathione binding

- In-frame and not-retained protein feature among the 13 regional features.
>>>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneFAM102Achr9:130715854chr9:130887720ENST00000373084-18157_268-104243Compositional biasNote=Ser-rich
HgeneFAM102Achr9:130715854chr9:130887720ENST00000373095-311157_26899385Compositional biasNote=Ser-rich
HgeneFAM102Achr9:130742271chr9:130887720ENST00000373084-18157_268-104243Compositional biasNote=Ser-rich
HgeneFAM102Achr9:130742271chr9:130887720ENST00000373095-111157_26848385Compositional biasNote=Ser-rich
HgeneFAM102Achr9:130715854chr9:130887720ENST00000373084-182_145-104243DomainC2 NT-type
HgeneFAM102Achr9:130715854chr9:130887720ENST00000373095-3112_14599385DomainC2 NT-type
HgeneFAM102Achr9:130742271chr9:130887720ENST00000373084-182_145-104243DomainC2 NT-type
HgeneFAM102Achr9:130742271chr9:130887720ENST00000373095-1112_14548385DomainC2 NT-type
TgenePTGES2chr9:130715854chr9:130887720ENST00000338961-071_5793378Topological domainLumenal
TgenePTGES2chr9:130715854chr9:130887720ENST00000338961-0775_37793378Topological domainCytoplasmic
TgenePTGES2chr9:130742271chr9:130887720ENST00000338961-071_5793378Topological domainLumenal
TgenePTGES2chr9:130742271chr9:130887720ENST00000338961-0775_37793378Topological domainCytoplasmic
TgenePTGES2chr9:130715854chr9:130887720ENST00000338961-0758_7493378TransmembraneHelical
TgenePTGES2chr9:130742271chr9:130887720ENST00000338961-0758_7493378TransmembraneHelical


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FusionGeneSequence for FAM102A_PTGES2


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.
>In-frame_FAM102A_ENST00000373095_chr9_130742271_-_PTGES2_ENST00000338961_chr9_130887720_-_333aa
MAFLMKKKKFKFQTTFTLEELTAVPFVNGVLFCKVRLLDGGDFVSLSSSSPCPAACSXPCTSTRRVPSAARSEPSSTSMPCPTRWWRXTL
CAGLRSSSPPTERCPSWWPRKEKARNNXMTPLSSSAPSRPTWCRGSPWKRSSPTTQPXRLXTSRARRXPSSAISTGSCSTRRRPSKCMVG
RRPGRRRXSGGSGRTTGWCTXSPPMCTARPPRLWRPLTTLSARASSEPWRVPWPSTWVQRPCTSSASDSRAGTASRTTCARTSMRLLTSG

>In-frame_FAM102A_ENST00000373095_chr9_130715854_-_PTGES2_ENST00000338961_chr9_130887720_-_384aa
MAFLMKKKKFKFQTTFTLEELTAVPFVNGVLFCKVRLLDGGDFVSLSSREEVQENCVRWRKRFTFVCKMSANPATGLLDPCVFRVSVRKE
LKGGKAYSKLSLSSRLQLTLYQYKTCPFCSKVRAFLDFHALPYQVVEVNPVRRAEIKFSSYRKVPILVAQEGESSQQLNDSSVIISALKT
YLVSGQPLEEIITYYPAMKAVNEQGKEVTEFGNKYWLMLNEKEAQQVYGGKEARTEEMKWRQWADDWLVHLISPNVYRTPTEALASFDYI
VREGKFGAVEGAVAKYMGAAAMYLISKRLKSRHRLQDNVREDLYEAADKWVAAVGKDRPFMGGQKPNLADLAVYGVLRVMEGLDAFDDLM


* Fusion transcript sequences (only coding sequence (CDS) region).
>In-frame_FAM102A_ENST00000373095_chr9_130742271_-_PTGES2_ENST00000338961_chr9_130887720_-_1001nt
ATGGCTTTCTTGATGAAGAAGAAGAAATTCAAATTCCAAACTACTTTCACCCTGGAGGAGCTGACTGCGGTTCCCTTCGTGAACGGGGTC
CTCTTCTGCAAGGTCCGGCTGCTGGATGGAGGGGATTTTGTCAGCTTGTCGTCAAGCTCTCCCTGTCCAGCCGCCTGCAGCTGACCCTGT
ACCAGTACAAGACGTGTCCCTTCTGCAGCAAGGTCCGAGCCTTCCTCGACTTCCATGCCCTGCCCTACCAGGTGGTGGAGGTGAACCCTG
TGCGCAGGGCTGAGATCAAGTTCTCCTCCTACAGAAAGGTGCCCATCCTGGTGGCCCAGGAAGGAGAAAGCTCGCAACAACTAAATGACT
CCTCTGTCATCATCAGCGCCCTCAAGACCTACCTGGTGTCGGGGCAGCCCCTGGAAGAGATCATCACCTACTACCCAGCCATGAAGGCTG
TGAACGAGCAGGGCAAGGAGGTGACCGAGTTCGGCAATAAGTACTGGCTCATGCTCAACGAGAAGGAGGCCCAGCAAGTGTATGGTGGGA
AGGAGGCCAGGACGGAGGAGATGAAGTGGCGGCAGTGGGCGGACGACTGGCTGGTGCACCTGATCTCCCCCAATGTGTACCGCACGCCCA
CCGAGGCTCTGGCGTCCTTTGACTACATTGTCCGCGAGGGCAAGTTCGGAGCCGTGGAGGGTGCCGTGGCCAAGTACATGGGTGCAGCGG
CCATGTACCTCATCAGCAAGCGACTCAAGAGCAGGCACCGCCTCCAGGACAACGTGCGCGAGGACCTCTATGAGGCTGCTGACAAGTGGG
TGGCTGCTGTGGGCAAGGACCGGCCCTTCATGGGGGGCCAGAAGCCGAATCTCGCTGATTTGGCGGTGTATGGCGTGCTGCGTGTGATGG
AGGGGCTGGATGCGTTCGATGACCTGATGCAGCACACGCACATCCAGCCCTGGTACCTGCGGGTGGAGAGGGCCATCACCGAGGCCTCCC

>In-frame_FAM102A_ENST00000373095_chr9_130715854_-_PTGES2_ENST00000338961_chr9_130887720_-_1152nt
ATGGCTTTCTTGATGAAGAAGAAGAAATTCAAATTCCAAACTACTTTCACCCTGGAGGAGCTGACTGCGGTTCCCTTCGTGAACGGGGTC
CTCTTCTGCAAGGTCCGGCTGCTGGATGGAGGGGATTTTGTCAGCTTGTCGTCAAGGGAGGAGGTACAGGAGAACTGTGTGCGGTGGCGA
AAGAGGTTCACCTTCGTGTGTAAGATGAGTGCTAACCCGGCCACCGGCCTGCTGGACCCCTGTGTCTTCCGTGTGTCTGTGCGCAAGGAG
CTGAAAGGCGGGAAGGCTTATTCCAAGCTCTCCCTGTCCAGCCGCCTGCAGCTGACCCTGTACCAGTACAAGACGTGTCCCTTCTGCAGC
AAGGTCCGAGCCTTCCTCGACTTCCATGCCCTGCCCTACCAGGTGGTGGAGGTGAACCCTGTGCGCAGGGCTGAGATCAAGTTCTCCTCC
TACAGAAAGGTGCCCATCCTGGTGGCCCAGGAAGGAGAAAGCTCGCAACAACTAAATGACTCCTCTGTCATCATCAGCGCCCTCAAGACC
TACCTGGTGTCGGGGCAGCCCCTGGAAGAGATCATCACCTACTACCCAGCCATGAAGGCTGTGAACGAGCAGGGCAAGGAGGTGACCGAG
TTCGGCAATAAGTACTGGCTCATGCTCAACGAGAAGGAGGCCCAGCAAGTGTATGGTGGGAAGGAGGCCAGGACGGAGGAGATGAAGTGG
CGGCAGTGGGCGGACGACTGGCTGGTGCACCTGATCTCCCCCAATGTGTACCGCACGCCCACCGAGGCTCTGGCGTCCTTTGACTACATT
GTCCGCGAGGGCAAGTTCGGAGCCGTGGAGGGTGCCGTGGCCAAGTACATGGGTGCAGCGGCCATGTACCTCATCAGCAAGCGACTCAAG
AGCAGGCACCGCCTCCAGGACAACGTGCGCGAGGACCTCTATGAGGCTGCTGACAAGTGGGTGGCTGCTGTGGGCAAGGACCGGCCCTTC
ATGGGGGGCCAGAAGCCGAATCTCGCTGATTTGGCGGTGTATGGCGTGCTGCGTGTGATGGAGGGGCTGGATGCGTTCGATGACCTGATG


* Fusion transcript sequences (Full-length transcript).
>In-frame_FAM102A_ENST00000373095_chr9_130742271_-_PTGES2_ENST00000338961_chr9_130887720_-_1829nt
CCGCGCGGCGTGAGCTCCCCGGACATCGCGTCTCGGGATGCTGCAAGCCAGCGCGGCCGCTCGCGCGCAGCCCCGCACCTCCGCCCCTGC
CTCTGCCTCCTGGGCCATGCCCTGCTGTTTACATGCCGGTGAGGTCCCCGGCCGCTCCGAACCCCTCCGAGCCCCGGCTCCCCGAGGGTG
AAGCCCGCCGGCCCGCGAACTGGACTGGTGGATCTCTCAGACCTGGGGCCCCGGACTCCGATCTCCGCCGTCTCCGCCACCATCAGGGCG
GGATCCGGCTCTGGTGTTTTGAGGAGGGGGTGTGGTGTAGGGAAAGGAATCCCGTCCCTCTCCACCTTTTTTCGCCTTCGGGGCTTCAGA
CTCAGGGAACTCGCTCATGGCTTTCTTGATGAAGAAGAAGAAATTCAAATTCCAAACTACTTTCACCCTGGAGGAGCTGACTGCGGTTCC
CTTCGTGAACGGGGTCCTCTTCTGCAAGGTCCGGCTGCTGGATGGAGGGGATTTTGTCAGCTTGTCGTCAAGCTCTCCCTGTCCAGCCGC
CTGCAGCTGACCCTGTACCAGTACAAGACGTGTCCCTTCTGCAGCAAGGTCCGAGCCTTCCTCGACTTCCATGCCCTGCCCTACCAGGTG
GTGGAGGTGAACCCTGTGCGCAGGGCTGAGATCAAGTTCTCCTCCTACAGAAAGGTGCCCATCCTGGTGGCCCAGGAAGGAGAAAGCTCG
CAACAACTAAATGACTCCTCTGTCATCATCAGCGCCCTCAAGACCTACCTGGTGTCGGGGCAGCCCCTGGAAGAGATCATCACCTACTAC
CCAGCCATGAAGGCTGTGAACGAGCAGGGCAAGGAGGTGACCGAGTTCGGCAATAAGTACTGGCTCATGCTCAACGAGAAGGAGGCCCAG
CAAGTGTATGGTGGGAAGGAGGCCAGGACGGAGGAGATGAAGTGGCGGCAGTGGGCGGACGACTGGCTGGTGCACCTGATCTCCCCCAAT
GTGTACCGCACGCCCACCGAGGCTCTGGCGTCCTTTGACTACATTGTCCGCGAGGGCAAGTTCGGAGCCGTGGAGGGTGCCGTGGCCAAG
TACATGGGTGCAGCGGCCATGTACCTCATCAGCAAGCGACTCAAGAGCAGGCACCGCCTCCAGGACAACGTGCGCGAGGACCTCTATGAG
GCTGCTGACAAGTGGGTGGCTGCTGTGGGCAAGGACCGGCCCTTCATGGGGGGCCAGAAGCCGAATCTCGCTGATTTGGCGGTGTATGGC
GTGCTGCGTGTGATGGAGGGGCTGGATGCGTTCGATGACCTGATGCAGCACACGCACATCCAGCCCTGGTACCTGCGGGTGGAGAGGGCC
ATCACCGAGGCCTCCCCAGCGCACTGAATGTCCCCGCGCAGAGCAGAGGGAAGGCAGCGGAAGACGCCAGCTGCCAGGGCCTGGGGCCAC
TGGGCCAGCGCCTGGCGATACTGGTTGGGGGCAGGATCATTCTGCCCCTTGTCCACGCACCCCCACCAGCCCTCTCGCTTCTAACACAGG
GCACCTGCTGGGGCTCAGGGATGTTAGGGACGAGTTCCAGCCCTGCCACTGCCCTGGGGCGACCCCTCCCTGTCCCTGCCTCCCTGCTCT
GCCGCCCCTCTTCCTGGACCCTCAGTGGCTGTCCCATGGCTACATCCTGTGGGTGGGGGCCCTCGACAGGACAGCAGGACGGTTTGTTTT
CAGTGGAATCCCATCCCTGGGTTCCCCTGGTTCCCACTCTTCCCAAGCCTCCCGGGACTGGGACATGTTTGCAATAAAGGAAAGGTTTGT

>In-frame_FAM102A_ENST00000373095_chr9_130715854_-_PTGES2_ENST00000338961_chr9_130887720_-_1980nt
CCGCGCGGCGTGAGCTCCCCGGACATCGCGTCTCGGGATGCTGCAAGCCAGCGCGGCCGCTCGCGCGCAGCCCCGCACCTCCGCCCCTGC
CTCTGCCTCCTGGGCCATGCCCTGCTGTTTACATGCCGGTGAGGTCCCCGGCCGCTCCGAACCCCTCCGAGCCCCGGCTCCCCGAGGGTG
AAGCCCGCCGGCCCGCGAACTGGACTGGTGGATCTCTCAGACCTGGGGCCCCGGACTCCGATCTCCGCCGTCTCCGCCACCATCAGGGCG
GGATCCGGCTCTGGTGTTTTGAGGAGGGGGTGTGGTGTAGGGAAAGGAATCCCGTCCCTCTCCACCTTTTTTCGCCTTCGGGGCTTCAGA
CTCAGGGAACTCGCTCATGGCTTTCTTGATGAAGAAGAAGAAATTCAAATTCCAAACTACTTTCACCCTGGAGGAGCTGACTGCGGTTCC
CTTCGTGAACGGGGTCCTCTTCTGCAAGGTCCGGCTGCTGGATGGAGGGGATTTTGTCAGCTTGTCGTCAAGGGAGGAGGTACAGGAGAA
CTGTGTGCGGTGGCGAAAGAGGTTCACCTTCGTGTGTAAGATGAGTGCTAACCCGGCCACCGGCCTGCTGGACCCCTGTGTCTTCCGTGT
GTCTGTGCGCAAGGAGCTGAAAGGCGGGAAGGCTTATTCCAAGCTCTCCCTGTCCAGCCGCCTGCAGCTGACCCTGTACCAGTACAAGAC
GTGTCCCTTCTGCAGCAAGGTCCGAGCCTTCCTCGACTTCCATGCCCTGCCCTACCAGGTGGTGGAGGTGAACCCTGTGCGCAGGGCTGA
GATCAAGTTCTCCTCCTACAGAAAGGTGCCCATCCTGGTGGCCCAGGAAGGAGAAAGCTCGCAACAACTAAATGACTCCTCTGTCATCAT
CAGCGCCCTCAAGACCTACCTGGTGTCGGGGCAGCCCCTGGAAGAGATCATCACCTACTACCCAGCCATGAAGGCTGTGAACGAGCAGGG
CAAGGAGGTGACCGAGTTCGGCAATAAGTACTGGCTCATGCTCAACGAGAAGGAGGCCCAGCAAGTGTATGGTGGGAAGGAGGCCAGGAC
GGAGGAGATGAAGTGGCGGCAGTGGGCGGACGACTGGCTGGTGCACCTGATCTCCCCCAATGTGTACCGCACGCCCACCGAGGCTCTGGC
GTCCTTTGACTACATTGTCCGCGAGGGCAAGTTCGGAGCCGTGGAGGGTGCCGTGGCCAAGTACATGGGTGCAGCGGCCATGTACCTCAT
CAGCAAGCGACTCAAGAGCAGGCACCGCCTCCAGGACAACGTGCGCGAGGACCTCTATGAGGCTGCTGACAAGTGGGTGGCTGCTGTGGG
CAAGGACCGGCCCTTCATGGGGGGCCAGAAGCCGAATCTCGCTGATTTGGCGGTGTATGGCGTGCTGCGTGTGATGGAGGGGCTGGATGC
GTTCGATGACCTGATGCAGCACACGCACATCCAGCCCTGGTACCTGCGGGTGGAGAGGGCCATCACCGAGGCCTCCCCAGCGCACTGAAT
GTCCCCGCGCAGAGCAGAGGGAAGGCAGCGGAAGACGCCAGCTGCCAGGGCCTGGGGCCACTGGGCCAGCGCCTGGCGATACTGGTTGGG
GGCAGGATCATTCTGCCCCTTGTCCACGCACCCCCACCAGCCCTCTCGCTTCTAACACAGGGCACCTGCTGGGGCTCAGGGATGTTAGGG
ACGAGTTCCAGCCCTGCCACTGCCCTGGGGCGACCCCTCCCTGTCCCTGCCTCCCTGCTCTGCCGCCCCTCTTCCTGGACCCTCAGTGGC
TGTCCCATGGCTACATCCTGTGGGTGGGGGCCCTCGACAGGACAGCAGGACGGTTTGTTTTCAGTGGAATCCCATCCCTGGGTTCCCCTG
GTTCCCACTCTTCCCAAGCCTCCCGGGACTGGGACATGTTTGCAATAAAGGAAAGGTTTGTGGCGCCTGTCATGGCAGGCATCTCATGGA


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FusionGenePPI for FAM102A_PTGES2


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page

.

check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors
FAM102ASH3GL1, SKAP1, ENKD1, NUP160, SERPINB8, TRIM25PTGES2H2AFX, MYC, UQCR11, HTT, PTGES2, EXOSC10, C1orf189, SHISA2, EID3, DLK1, COQ9, NDUFA4, C15orf48, ABCF2, ATP6V0D1, SCGB2A2, RANBP6, FUZ, C5orf28, LRP1, UQCRQ


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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RelatedDrugs for FAM102A_PTGES2


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for FAM102A_PTGES2


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
TgenePTGES2C0040136Thyroid Neoplasm1CTD_human